BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= AA00544
(402 letters)
Database: nr
5,470,121 sequences; 1,894,087,724 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52424726|ref|YP_087863.1| Gsp protein [Mannheimia succin... 645 0.0
gi|152978480|ref|YP_001344109.1| Glutathionylspermidine ami... 643 0.0
gi|152971933|ref|YP_001337042.1| bifunctional glutathionyls... 550 e-155
gi|157085757|gb|ABV15435.1| hypothetical protein CKO_04379 ... 546 e-154
gi|16130888|ref|NP_417462.1| fused glutathionylspermidine a... 543 e-153
gi|75196952|ref|ZP_00707022.1| COG0754: Glutathionylspermid... 543 e-153
gi|110806891|ref|YP_690411.1| glutathionylspermidine synthe... 543 e-153
gi|15803533|ref|NP_289566.1| glutathionylspermidine synthet... 543 e-153
gi|26249556|ref|NP_755596.1| Glutathionylspermidine amidase... 542 e-152
gi|75240556|ref|ZP_00724484.1| COG0754: Glutathionylspermid... 542 e-152
gi|91212402|ref|YP_542388.1| glutathionylspermidine synthas... 542 e-152
gi|110643227|ref|YP_670957.1| glutathionylspermidine synthe... 541 e-152
gi|146313030|ref|YP_001178104.1| Glutathionylspermidine syn... 539 e-151
gi|16761917|ref|NP_457534.1| glutathionylspermidine synthet... 539 e-151
gi|56415081|ref|YP_152156.1| glutathionylspermidine synthet... 539 e-151
gi|90578770|ref|ZP_01234580.1| glutathionylspermidine synth... 503 e-141
gi|119944984|ref|YP_942664.1| fused glutathionylspermidine ... 395 e-108
gi|88858189|ref|ZP_01132831.1| bifunctional: glutathionylsp... 385 e-105
gi|83595052|ref|YP_428804.1| Glutathionylspermidine amidase... 383 e-104
gi|152994258|ref|YP_001339093.1| Glutathionylspermidine ami... 380 e-104
gi|77361371|ref|YP_340946.1| bifunctional: glutathionylsper... 370 e-100
gi|71417579|ref|XP_810600.1| trypanothione synthetase [Tryp... 172 3e-41
gi|71654931|ref|XP_816076.1| trypanothione synthetase [Tryp... 169 3e-40
gi|16588445|gb|AAL26803.1|AF311782_1 trypanothione syntheta... 168 5e-40
gi|24528130|emb|CAD23679.1| trypanothione synthetase [Leish... 165 4e-39
gi|148283952|gb|ABQ57409.1| trypanothione synthetase [Leish... 159 2e-37
gi|29468074|gb|AAO00721.1| trypanothione synthetase [Trypan... 158 6e-37
gi|84043680|ref|XP_951630.1| trypanothione synthetase [Tryp... 158 6e-37
gi|24474936|emb|CAC87573.1| trypanothione synthetase [Trypa... 155 3e-36
gi|51236703|gb|AAT99012.1| trypanothione synthetase [Crithi... 155 5e-36
gi|26400865|sp|O60993|TRYS_CRIFA Trypanothione synthetase (... 155 6e-36
gi|146091037|ref|XP_001466426.1| trypanothione synthetase [... 154 1e-35
gi|154339996|ref|XP_001565955.1| trypanothione synthetase, ... 154 1e-35
gi|73544497|ref|XP_848143.1| trypanothione synthetase [Leis... 152 3e-35
gi|26394307|sp|P90518|GSP_CRIFA Glutathionylspermidine synt... 110 2e-22
gi|146089219|ref|XP_001466279.1| glutathionylspermidine syn... 101 1e-19
gi|71667801|ref|XP_820846.1| glutathionylspermidine synthas... 100 2e-19
gi|153876761|ref|ZP_02003917.1| D-alanyl-glycyl endopeptida... 97 2e-18
gi|71656485|ref|XP_816789.1| trypanothione synthetase [Tryp... 94 2e-17
gi|71664993|ref|XP_819471.1| trypanothione synthetase [Tryp... 92 4e-17
gi|71665703|ref|XP_819818.1| trypanothione synthetase-like ... 88 1e-15
gi|72392547|ref|XP_847074.1| trypanothione synthetase, puta... 83 3e-14
gi|118361736|ref|XP_001014096.1| Glutathionylspermidine syn... 82 9e-14
gi|145536403|ref|XP_001453929.1| hypothetical protein [Para... 79 7e-13
gi|154344268|ref|XP_001568078.1| D-alanyl-glycyl endopeptid... 78 1e-12
gi|145526691|ref|XP_001449151.1| hypothetical protein [Para... 77 3e-12
gi|145497204|ref|XP_001434591.1| hypothetical protein [Para... 76 4e-12
gi|118361730|ref|XP_001014093.1| Glutathionylspermidine syn... 75 1e-11
gi|145500608|ref|XP_001436287.1| hypothetical protein [Para... 74 1e-11
gi|145494796|ref|XP_001433392.1| hypothetical protein [Para... 74 2e-11
gi|145494794|ref|XP_001433391.1| hypothetical protein [Para... 73 3e-11
gi|145493617|ref|XP_001432804.1| hypothetical protein [Para... 73 3e-11
gi|145542015|ref|XP_001456695.1| hypothetical protein [Para... 73 4e-11
gi|118348648|ref|XP_001007799.1| Glutathionylspermidine syn... 71 2e-10
gi|71424221|ref|XP_812721.1| D-alanyl-glycyl endopeptidase-... 70 2e-10
gi|145509885|ref|XP_001440881.1| hypothetical protein [Para... 70 3e-10
gi|68130089|emb|CAJ09397.1| trypanothione synthetase-like p... 69 8e-10
gi|71399874|ref|XP_802893.1| D-alanyl-glycyl endopeptidase-... 68 1e-09
gi|146105250|ref|XP_001470013.1| trypanothione synthetase-l... 68 1e-09
gi|146098165|ref|XP_001468343.1| D-alanyl-glycyl endopeptid... 67 3e-09
gi|145514600|ref|XP_001443205.1| hypothetical protein [Para... 64 1e-08
gi|68129119|emb|CAJ06795.1| D-alanyl-glycyl endopeptidase-l... 64 1e-08
gi|84043610|ref|XP_951595.1| D-alanyl-glycyl endopeptidase ... 64 2e-08
gi|71413979|ref|XP_809108.1| D-alanyl-glycyl endopeptidase-... 63 4e-08
gi|83649227|ref|YP_437662.1| Glutathionylspermidine synthas... 62 5e-08
gi|71413981|ref|XP_809109.1| D-alanyl-glycyl endopeptidase-... 62 5e-08
gi|71388835|ref|XP_802159.1| D-alanyl-glycyl endopeptidase-... 60 3e-07
gi|87200372|ref|YP_497629.1| glutathionylspermidine synthas... 57 2e-06
gi|153832455|ref|ZP_01985122.1| glutathionylspermidine synt... 57 2e-06
gi|156932414|ref|YP_001436330.1| hypothetical protein ESA_0... 57 3e-06
gi|37528140|ref|NP_931485.1| hypothetical protein plu4309 [... 56 3e-06
gi|120597090|ref|YP_961664.1| CHAP domain containing protei... 56 5e-06
gi|54301720|ref|YP_131713.1| hypothetical protein PBPRB0040... 56 5e-06
gi|84043608|ref|XP_951594.1| D-alanyl-glycyl endopeptidase ... 55 6e-06
gi|150006044|ref|YP_001300788.1| glutathionylspermidine syn... 55 6e-06
gi|146291512|ref|YP_001181936.1| CHAP domain containing pro... 55 8e-06
>gi|52424726|ref|YP_087863.1| Gsp protein [Mannheimia succiniciproducens MBEL55E]
gi|52306778|gb|AAU37278.1| Gsp protein [Mannheimia succiniciproducens MBEL55E]
Length = 629
Score = 645 bits (1665), Expect = 0.0, Method: Composition-based stats.
Identities = 302/379 (79%), Positives = 328/379 (86%)
Query: 1 MPDRSPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQ 60
M + SPNI THD FGSLLGYAPGG+AIYSSDY TAD EYPDDAAFRSYLG EYMGYKWQ
Sbjct: 1 MSEISPNIPTHDAFGSLLGYAPGGIAIYSSDYETADKNEYPDDAAFRSYLGREYMGYKWQ 60
Query: 61 CVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALL 120
CVEFARRYLYLN+GMVFTDVGMAYEIFSLRFLRQVVNDAL+PLQA+ANG K++PE GALL
Sbjct: 61 CVEFARRYLYLNHGMVFTDVGMAYEIFSLRFLRQVVNDALVPLQAYANGSKKSPEPGALL 120
Query: 121 IWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQD 180
IWQEGGEF+ TGHVA+ITEV DK+RIAEQNVIH RLPSGQQWTRELPM+VT Y L D
Sbjct: 121 IWQEGGEFQETGHVAIITEVFNDKIRIAEQNVIHYRLPSGQQWTRELPMSVTEQGYILHD 180
Query: 181 TFDDTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYV 240
TFDDTEILGWMIQTD+ +SLPQP APE L IHAEHIEN+GQF WLNE +P E YV
Sbjct: 181 TFDDTEILGWMIQTDDSTYSLPQPTAAPESLEIHAEHIENKGQFDGKWLNESDPFEKLYV 240
Query: 241 KAMKGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKL 300
AM GH V+ DQYRYF +SE+A+HELIRATNELHLMYLHAT+KVL DD LL+YFNIPKL
Sbjct: 241 TAMNGHQVSRTDQYRYFTISETAKHELIRATNELHLMYLHATNKVLNDDNLLKYFNIPKL 300
Query: 301 LWPRLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLT 360
LWPRLRLSW+NRRYQT++GR+DFCLDERGLKVYEYN DSASCHAEAGAIL WA +AGL
Sbjct: 301 LWPRLRLSWENRRYQTVSGRLDFCLDERGLKVYEYNADSASCHAEAGAILGRWAKVAGLD 360
Query: 361 LRHDPGEGLRNALADTWKH 379
DPG LRNALAD WKH
Sbjct: 361 NGEDPGAHLRNALADCWKH 379
>gi|152978480|ref|YP_001344109.1| Glutathionylspermidine amidase [Actinobacillus succinogenes 130Z]
gi|150840203|gb|ABR74174.1| Glutathionylspermidine amidase [Actinobacillus succinogenes 130Z]
Length = 628
Score = 643 bits (1659), Expect = 0.0, Method: Composition-based stats.
Identities = 299/382 (78%), Positives = 326/382 (85%)
Query: 1 MPDRSPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQ 60
MPD SPNI THDPFGSLLGYAPGG+AIYSSDY TAD QEYPDDAAFRSY+G EYMGYKWQ
Sbjct: 1 MPDISPNIPTHDPFGSLLGYAPGGIAIYSSDYETADKQEYPDDAAFRSYVGREYMGYKWQ 60
Query: 61 CVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALL 120
CVEFARRYLYLN+G VFTDVGMAYEIF+LRFLRQVVNDA+LPLQAFANG ++ PE GALL
Sbjct: 61 CVEFARRYLYLNHGWVFTDVGMAYEIFALRFLRQVVNDAILPLQAFANGSQKKPEAGALL 120
Query: 121 IWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQD 180
IWQ+GGEFKHTGHVA+ITEVL +K+RIAEQNV+HSRLPSGQQWTRELPMTV Y L D
Sbjct: 121 IWQDGGEFKHTGHVAIITEVLDNKIRIAEQNVLHSRLPSGQQWTRELPMTVDENGYLLHD 180
Query: 181 TFDDTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYV 240
TFDDTEILGWMIQTD+ FS+PQPMP + L I A HIEN GQF WLNE+N E A+
Sbjct: 181 TFDDTEILGWMIQTDDTSFSIPQPMPERDLLEIKANHIENHGQFDGKWLNENNDFEKAFA 240
Query: 241 KAMKGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKL 300
AM+GH V+ DQYRYF +SESA ELIRATNELHLMYLHATDKVLKDD LL+ FNIPKL
Sbjct: 241 TAMQGHCVSRTDQYRYFTISESAHQELIRATNELHLMYLHATDKVLKDDNLLKLFNIPKL 300
Query: 301 LWPRLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLT 360
LWPRLRLSWQNRRYQTI+GR+DFC+D+ GLKVYEYN DSASCHAEAG IL WA AGLT
Sbjct: 301 LWPRLRLSWQNRRYQTISGRLDFCMDKNGLKVYEYNADSASCHAEAGDILNRWAVQAGLT 360
Query: 361 LRHDPGEGLRNALADTWKHSHA 382
+PG LR+ LAD WKHS A
Sbjct: 361 AGKNPGADLRDVLADCWKHSQA 382
>gi|152971933|ref|YP_001337042.1| bifunctional glutathionylspermidine amidase/glutathionylspermidine
synthetase [Klebsiella pneumoniae subsp. pneumoniae MGH
78578]
gi|150956782|gb|ABR78812.1| bifunctional glutathionylspermidine amidase/glutathionylspermidine
synthetase [Klebsiella pneumoniae subsp. pneumoniae MGH
78578]
Length = 621
Score = 550 bits (1416), Expect = e-155, Method: Composition-based stats.
Identities = 255/370 (68%), Positives = 295/370 (79%), Gaps = 2/370 (0%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG+LLGYAPGGVAIYSS+Y++ + Q+YPDDA FRSY+G EYMG+KWQCVEFARR+L+L
Sbjct: 11 PFGTLLGYAPGGVAIYSSNYSSLNPQDYPDDATFRSYIGNEYMGHKWQCVEFARRFLFLT 70
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
YG VFTDVGMAYEIFSLRFLR+VVND +LPLQAFANG +R P G+LLIWQ+GGEFKHTG
Sbjct: 71 YGFVFTDVGMAYEIFSLRFLREVVNDNILPLQAFANGSRRPPIAGSLLIWQKGGEFKHTG 130
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEILGWMI 192
HVAVIT+++ +KVRIAEQNVIHS LP GQQWTREL + V GRY ++DTF DTEILGWMI
Sbjct: 131 HVAVITQLVGNKVRIAEQNVIHSPLPQGQQWTRELTLEVNDGRYTIKDTFADTEILGWMI 190
Query: 193 QTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAMKGHIVNHGD 252
QT + E SLPQP+ E + I + N GQF WLNE +PL+ AYV A GH +N D
Sbjct: 191 QTADTEHSLPQPVLPGEAMAIKGARLPNNGQFRGKWLNEKDPLQKAYVAA-NGHFINQ-D 248
Query: 253 QYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSWQNR 312
Y+YF +SESA+ ELI+ATNELHLMYLHATDKV+KDD LL F+IPK+LWPRLRLSWQ R
Sbjct: 249 PYQYFTISESAEQELIKATNELHLMYLHATDKVMKDDNLLALFDIPKILWPRLRLSWQRR 308
Query: 313 RYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRHDPGEGLRNA 372
R+ ITGRMDFC+DERGLKVYEYN DSASCH E G IL W H+P EGL +
Sbjct: 309 RHHMITGRMDFCMDERGLKVYEYNADSASCHTEGGLILEQWLKQGYYGTGHNPAEGLLDE 368
Query: 373 LADTWKHSHA 382
LA WKHS A
Sbjct: 369 LAGAWKHSRA 378
>gi|157085757|gb|ABV15435.1| hypothetical protein CKO_04379 [Citrobacter koseri ATCC BAA-895]
Length = 620
Score = 546 bits (1408), Expect = e-154, Method: Composition-based stats.
Identities = 260/379 (68%), Positives = 302/379 (79%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T D PFG+LLGYAPGGVAIYSSDY++ D +EY DDAAFRSY+G EYMG+KWQCVE
Sbjct: 2 SKGTTRQDAPFGTLLGYAPGGVAIYSSDYSSLDPREYSDDAAFRSYIGNEYMGHKWQCVE 61
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAP GALLIWQ
Sbjct: 62 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWQ 121
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
GGEFK TGHVA+IT++L +K+RIAEQNVIH+ LP GQQWTREL M V G Y L+DTFD
Sbjct: 122 NGGEFKDTGHVAIITQLLDNKIRIAEQNVIHTPLPPGQQWTRELDMVVENGCYTLRDTFD 181
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ ++SLPQP A + L I +E +GQF WL+E +PL+ AYV A
Sbjct: 182 DTTILGWMIQTEDTQYSLPQPDIANDSLKIRGARLEEKGQFDGKWLDERDPLQKAYVLA- 240
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
GH++N D ++YF ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 241 NGHVINQ-DPHQYFTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 299
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA H
Sbjct: 300 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEKGYTGKGH 359
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 360 NPAEGLINELAGAWKHSLA 378
>gi|16130888|ref|NP_417462.1| fused glutathionylspermidine amidase/glutathionylspermidine
synthetase [Escherichia coli K12]
gi|30064343|ref|NP_838514.1| glutathionylspermidine synthetase/amidase [Shigella flexneri 2a
str. 2457T]
gi|56480234|ref|NP_708806.2| glutathionylspermidine synthetase/amidase [Shigella flexneri 2a
str. 301]
gi|74313533|ref|YP_311952.1| glutathionylspermidine synthetase/amidase [Shigella sonnei Ss046]
gi|75178887|ref|ZP_00698923.1| COG0754: Glutathionylspermidine synthase [Shigella boydii BS512]
gi|75187810|ref|ZP_00701077.1| COG0754: Glutathionylspermidine synthase [Escherichia coli E24377A]
gi|75212366|ref|ZP_00712390.1| COG0754: Glutathionylspermidine synthase [Escherichia coli B171]
gi|75229325|ref|ZP_00715884.1| COG0754: Glutathionylspermidine synthase [Escherichia coli B7A]
gi|75239428|ref|ZP_00723399.1| COG0754: Glutathionylspermidine synthase [Escherichia coli E110019]
gi|75259934|ref|ZP_00731212.1| COG0754: Glutathionylspermidine synthase [Escherichia coli E22]
gi|82545274|ref|YP_409221.1| glutathionylspermidine synthetase/amidase [Shigella boydii Sb227]
gi|82778243|ref|YP_404592.1| glutathionylspermidine synthetase/amidase [Shigella dysenteriae
Sd197]
gi|83587565|ref|ZP_00926192.1| COG0754: Glutathionylspermidine synthase [Escherichia coli 101-1]
gi|89109763|ref|AP_003543.1| fused glutathionylspermidine amidase and glutathionylspermidine
synthetase [Escherichia coli W3110]
gi|124526092|ref|ZP_01698097.1| Glutathionylspermidine synthase [Escherichia coli B]
gi|84028738|sp|P0AES0|GSP_ECOLI Bifunctional glutathionylspermidine synthetase/amidase [Includes:
Glutathionylspermidine synthase (Glutathione:spermidine
ligase [ADP-forming]) (GSP synthetase);
Glutathionylspermidine amidase (Glutathionylspermidine
amidohydrolase [spermidine-forming]) (GSP amidase)]
gi|84028739|sp|P0AES1|GSP_SHIFL Bifunctional glutathionylspermidine synthetase/amidase [Includes:
Glutathionylspermidine synthase (Glutathione:spermidine
ligase [ADP-forming]) (GSP synthetase);
Glutathionylspermidine amidase (Glutathionylspermidine
amidohydrolase [spermidine-forming]) (GSP amidase)]
gi|122920694|pdb|2IO7|A Chain A, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE INCOMPLEX WITH MG2+ AND AMPPNP
gi|122920695|pdb|2IO7|B Chain B, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE INCOMPLEX WITH MG2+ AND AMPPNP
gi|122920697|pdb|2IO8|A Chain A, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE INCOMPLEX WITH MG2+ AND ADP
gi|122920698|pdb|2IO8|B Chain B, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE INCOMPLEX WITH MG2+ AND ADP
gi|122920700|pdb|2IO9|A Chain A, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE INCOMPLEX WITH MG2+ ,GSH AND ADP
gi|122920701|pdb|2IO9|B Chain B, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE INCOMPLEX WITH MG2+ ,GSH AND ADP
gi|122920704|pdb|2IOA|A Chain A, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE INCOMPLEX WITH MG2+ AND ADP AND
Phosphinate Inhibitor
gi|122920705|pdb|2IOA|B Chain B, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE INCOMPLEX WITH MG2+ AND ADP AND
Phosphinate Inhibitor
gi|122920707|pdb|2IOB|A Chain A, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE APO PROTEIN
gi|122920708|pdb|2IOB|B Chain B, E. Coli Bifunctional Glutathionylspermidine
SynthetaseAMIDASE APO PROTEIN
gi|861186|gb|AAC43339.1| glutathionylspermidine synthetase/amidase
gi|882517|gb|AAA69155.1| ORF_f619
gi|1789361|gb|AAC76024.1| fused glutathionylspermidine amidase/glutathionylspermidine
synthetase [Escherichia coli K12]
gi|30042600|gb|AAP18324.1| glutathionylspermidine synthetase/amidase [Shigella flexneri 2a
str. 2457T]
gi|56383785|gb|AAN44513.2| glutathionylspermidine synthetase/amidase [Shigella flexneri 2a
str. 301]
gi|73857010|gb|AAZ89717.1| glutathionylspermidine synthetase/amidase [Shigella sonnei Ss046]
gi|81242391|gb|ABB63101.1| glutathionylspermidine synthetase/amidase [Shigella dysenteriae
Sd197]
gi|81246685|gb|ABB67393.1| glutathionylspermidine synthetase/amidase [Shigella boydii Sb227]
gi|85675796|dbj|BAE77049.1| fused glutathionylspermidine amidase and glutathionylspermidine
synthetase [Escherichia coli W3110]
gi|124502196|gb|EAY49656.1| Glutathionylspermidine synthase [Escherichia coli B]
gi|157077878|gb|ABV17586.1| glutathionylspermidine amidase/glutathionylspermidine synthase
[Escherichia coli E24377A]
Length = 619
Score = 543 bits (1400), Expect = e-153, Method: Composition-based stats.
Identities = 260/379 (68%), Positives = 299/379 (78%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDY++ D QEY DDA FRSY+ EYMG+KWQCVE
Sbjct: 2 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVE 61
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAP GALLIW
Sbjct: 62 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWD 121
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEFK TGHVA+IT++ +KVRIAEQNVIHS LP GQQWTREL M V G Y L+DTFD
Sbjct: 122 KGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGCYTLKDTFD 181
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ E+SLPQP A E L I +EN+GQF WL+E +PL+ AYV+A
Sbjct: 182 DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQA- 240
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
G ++N D Y Y+ ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 241 NGQVINQ-DPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 299
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA
Sbjct: 300 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGF 359
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 360 NPAEGLINELAGAWKHSRA 378
>gi|75196952|ref|ZP_00707022.1| COG0754: Glutathionylspermidine synthase [Escherichia coli HS]
gi|75515214|ref|ZP_00737398.1| COG0754: Glutathionylspermidine synthase [Escherichia coli 53638]
gi|157068148|gb|ABV07403.1| glutathionylspermidine amidase/glutathionylspermidine synthase
[Escherichia coli HS]
Length = 619
Score = 543 bits (1400), Expect = e-153, Method: Composition-based stats.
Identities = 260/379 (68%), Positives = 299/379 (78%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDY++ D QEY DDA FRSY+ EYMG+KWQCVE
Sbjct: 2 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVE 61
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAP GALLIW
Sbjct: 62 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWD 121
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEFK TGHVA+IT++ +KVRIAEQNVIHS LP GQQWTREL M V G Y L+DTFD
Sbjct: 122 KGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGCYTLKDTFD 181
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ E+SLPQP A E L I +EN+GQF WL+E +PL+ AYV+A
Sbjct: 182 DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQA- 240
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
G ++N D Y Y+ ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 241 NGQVINQ-DPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 299
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA
Sbjct: 300 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGF 359
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 360 NPAEGLINELAGAWKHSRA 378
>gi|110806891|ref|YP_690411.1| glutathionylspermidine synthetase/amidase [Shigella flexneri 5 str.
8401]
gi|110616439|gb|ABF05106.1| glutathionylspermidine synthetase/amidase [Shigella flexneri 5 str.
8401]
Length = 620
Score = 543 bits (1400), Expect = e-153, Method: Composition-based stats.
Identities = 260/379 (68%), Positives = 299/379 (78%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDY++ D QEY DDA FRSY+ EYMG+KWQCVE
Sbjct: 3 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVE 62
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAP GALLIW
Sbjct: 63 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWD 122
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEFK TGHVA+IT++ +KVRIAEQNVIHS LP GQQWTREL M V G Y L+DTFD
Sbjct: 123 KGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGCYTLKDTFD 182
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ E+SLPQP A E L I +EN+GQF WL+E +PL+ AYV+A
Sbjct: 183 DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQA- 241
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
G ++N D Y Y+ ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 242 NGQVINQ-DPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 300
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA
Sbjct: 301 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGF 360
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 361 NPAEGLINELAGAWKHSRA 379
>gi|15803533|ref|NP_289566.1| glutathionylspermidine synthetase/amidase [Escherichia coli O157:H7
EDL933]
gi|15833127|ref|NP_311900.1| glutathionylspermidine synthetase/amidase [Escherichia coli O157:H7
str. Sakai]
gi|12517552|gb|AAG58125.1|AE005529_3 glutathionylspermidine synthetase/amidase [Escherichia coli O157:H7
EDL933]
gi|13363345|dbj|BAB37296.1| glutathionylspermidine synthetase/amidase [Escherichia coli O157:H7
str. Sakai]
Length = 619
Score = 543 bits (1399), Expect = e-153, Method: Composition-based stats.
Identities = 260/379 (68%), Positives = 299/379 (78%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDY++ D QEY DDA FRSY+ EYMG+KWQCVE
Sbjct: 2 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVE 61
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAP GALLIW
Sbjct: 62 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWD 121
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEFK TGHVA+IT++ +KVRIAEQNVIHS LP GQQWTREL M V G Y L+DTFD
Sbjct: 122 KGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGCYTLKDTFD 181
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ E+SLPQP A E L I +EN+GQF WL+E +PL+ AYV+A
Sbjct: 182 DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQA- 240
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
G ++N D Y Y+ ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 241 NGQVINQ-DPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 299
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA
Sbjct: 300 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGF 359
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 360 NPAEGLINELAGAWKHSRA 378
>gi|26249556|ref|NP_755596.1| Glutathionylspermidine amidase [Escherichia coli CFT073]
gi|26109964|gb|AAN82169.1|AE016766_257 Glutathionylspermidine synthase [Escherichia coli CFT073]
Length = 620
Score = 542 bits (1397), Expect = e-152, Method: Composition-based stats.
Identities = 259/379 (68%), Positives = 299/379 (78%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDY++ D QEY DDA FRSY+ EYMG+KWQCVE
Sbjct: 3 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVE 62
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAP GALLIW
Sbjct: 63 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWD 122
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEFK TGHVA+IT++ +KVRIAEQNVIH+ LP GQQWTREL M V G Y L+DTFD
Sbjct: 123 KGGEFKDTGHVAIITQLHGNKVRIAEQNVIHTPLPQGQQWTRELEMVVENGGYTLKDTFD 182
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ E+SLPQP A E L I +EN+GQF WL+E +PL+ AYV+A
Sbjct: 183 DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQA- 241
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
G ++N D Y Y+ ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 242 NGQVINQ-DPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 300
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA
Sbjct: 301 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGF 360
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 361 NPAEGLINELAGAWKHSRA 379
>gi|75240556|ref|ZP_00724484.1| COG0754: Glutathionylspermidine synthase [Escherichia coli F11]
Length = 619
Score = 542 bits (1396), Expect = e-152, Method: Composition-based stats.
Identities = 259/379 (68%), Positives = 299/379 (78%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDY++ D QEY DDA FRSY+ EYMG+KWQCVE
Sbjct: 2 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVE 61
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAP GALLIW
Sbjct: 62 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWD 121
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEFK TGHVA+IT++ +KVRIAEQNVIH+ LP GQQWTREL M V G Y L+DTFD
Sbjct: 122 KGGEFKDTGHVAIITQLHGNKVRIAEQNVIHTPLPQGQQWTRELEMVVENGGYTLKDTFD 181
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ E+SLPQP A E L I +EN+GQF WL+E +PL+ AYV+A
Sbjct: 182 DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQA- 240
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
G ++N D Y Y+ ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 241 NGQVINQ-DPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 299
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA
Sbjct: 300 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGF 359
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 360 NPAEGLINELAGAWKHSRA 378
>gi|91212402|ref|YP_542388.1| glutathionylspermidine synthase [Escherichia coli UTI89]
gi|117625294|ref|YP_854466.1| glutathionylspermidine synthase [Escherichia coli APEC O1]
gi|91073976|gb|ABE08857.1| glutathionylspermidine synthase [Escherichia coli UTI89]
gi|115514418|gb|ABJ02493.1| glutathionylspermidine synthase [Escherichia coli APEC O1]
Length = 620
Score = 542 bits (1396), Expect = e-152, Method: Composition-based stats.
Identities = 259/379 (68%), Positives = 299/379 (78%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDY++ D QEY DDA FRSY+ EYMG+KWQCVE
Sbjct: 3 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVE 62
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAP GALLIW
Sbjct: 63 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWD 122
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEFK TGHVA+IT++ +KVRIAEQNVIH+ LP GQQWTREL M V G Y L+DTFD
Sbjct: 123 KGGEFKDTGHVAIITQLHGNKVRIAEQNVIHTPLPQGQQWTRELEMVVENGGYTLKDTFD 182
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ E+SLPQP A E L I +EN+GQF WL+E +PL+ AYV+A
Sbjct: 183 DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQA- 241
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
G ++N D Y Y+ ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 242 NGQVINQ-DPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 300
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA
Sbjct: 301 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGF 360
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 361 NPAEGLINELAGAWKHSRA 379
>gi|110643227|ref|YP_670957.1| glutathionylspermidine synthetase/amidase [Escherichia coli 536]
gi|110344819|gb|ABG71056.1| glutathionylspermidine synthetase/amidase [Escherichia coli 536]
Length = 619
Score = 541 bits (1393), Expect = e-152, Method: Composition-based stats.
Identities = 258/379 (68%), Positives = 298/379 (78%), Gaps = 3/379 (0%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDY++ D QEY DDA FRSY+ EYMG+KWQCVE
Sbjct: 2 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVE 61
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+V+ND +LPLQAF NG RAP GALLIW
Sbjct: 62 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVINDNILPLQAFPNGSPRAPVAGALLIWD 121
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEFK TGHVA+IT++ +KVRIAEQNVIHS LP GQQWTREL M V G Y L+DTFD
Sbjct: 122 KGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGGYTLKDTFD 181
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQT++ E+SLPQP A E L I +EN+GQF WL+E +PL+ AY +A
Sbjct: 182 DTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYAQA- 240
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
G ++N D Y Y+ ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 241 NGQVINQ-DPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 299
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA
Sbjct: 300 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGF 359
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 360 NPAEGLINELAGAWKHSRA 378
>gi|146313030|ref|YP_001178104.1| Glutathionylspermidine synthase [Enterobacter sp. 638]
gi|145319906|gb|ABP62053.1| Glutathionylspermidine synthase [Enterobacter sp. 638]
Length = 620
Score = 539 bits (1389), Expect = e-151, Method: Composition-based stats.
Identities = 251/379 (66%), Positives = 299/379 (78%), Gaps = 2/379 (0%)
Query: 4 RSPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
R +++ PFG+LLGYAPGGVAIYSS+Y++ D ++YP+DA FRSY+G EYMG+KWQCVE
Sbjct: 2 RKGKLSSDAPFGTLLGYAPGGVAIYSSNYSSLDPRQYPEDAEFRSYIGNEYMGHKWQCVE 61
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG VFTDVGMA+EIFSLRFLRQVVND +LPLQAFANG KRAP+ GALLIW+
Sbjct: 62 FARRFLFLNYGYVFTDVGMAWEIFSLRFLRQVVNDNILPLQAFANGSKRAPDAGALLIWR 121
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
GEF TGHVA+IT+++ DKVRIAEQNV+HS LP GQQWTREL ++V GRY L DT+
Sbjct: 122 NDGEFSETGHVAIITQLMGDKVRIAEQNVLHSPLPIGQQWTRELRLSVENGRYTLHDTYT 181
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQTD+ E SLPQP PE L + ++N+ QF WLNE++ L+ AYV+A
Sbjct: 182 DTHILGWMIQTDDTEHSLPQPQIEPELLNLTGARLQNKRQFDGKWLNENDSLQQAYVRA- 240
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
GH++N D +YF ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 241 NGHVINK-DPCQYFTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 299
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH E G IL W H
Sbjct: 300 RLRLSWQWRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEGGLILEEWVKNGYRGTGH 359
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL L WKHS+A
Sbjct: 360 NPAEGLLEELTGAWKHSNA 378
>gi|16761917|ref|NP_457534.1| glutathionylspermidine synthetase/amidase [Salmonella enterica
subsp. enterica serovar Typhi str. CT18]
gi|16766439|ref|NP_462054.1| glutathionylspermidine synthetase/glutathionylspermidine amidase
[Salmonella typhimurium LT2]
gi|29143404|ref|NP_806746.1| glutathionylspermidine synthetase/amidase [Salmonella enterica
subsp. enterica serovar Typhi Ty2]
gi|62181650|ref|YP_218067.1| glutathionylspermidine synthetase; glutathionylspermidine amidase
[Salmonella enterica subsp. enterica serovar
Choleraesuis str. SC-B67]
gi|25512118|pir||AC0884 glutathionylspermidine synthetase/amidase [imported] - Salmonella
enterica subsp. enterica serovar Typhi (strain CT18)
gi|16421693|gb|AAL22013.1| glutathionylspermidine synthetase; glutathionylspermidine amidase
[Salmonella typhimurium LT2]
gi|16504219|emb|CAD02971.1| glutathionylspermidine synthetase/amidase [Salmonella enterica
subsp. enterica serovar Typhi]
gi|29139038|gb|AAO70606.1| glutathionylspermidine synthetase/amidase [Salmonella enterica
subsp. enterica serovar Typhi Ty2]
gi|62129283|gb|AAX66986.1| glutathionylspermidine synthetase; glutathionylspermidine amidase
[Salmonella enterica subsp. enterica serovar
Choleraesuis str. SC-B67]
Length = 618
Score = 539 bits (1389), Expect = e-151, Method: Composition-based stats.
Identities = 258/379 (68%), Positives = 300/379 (79%), Gaps = 4/379 (1%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDYN+ D + DDAAFRSY+ EYMG+KWQCVE
Sbjct: 2 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYNSLDPWD-DDDAAFRSYIDDEYMGHKWQCVE 60
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAPE GALLIWQ
Sbjct: 61 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPEAGALLIWQ 120
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEF TGHVA+IT++L +K+RIAEQNVIH+ LP GQQWTREL M V G Y L+DTFD
Sbjct: 121 KGGEFNETGHVAIITQLLDNKIRIAEQNVIHTPLPPGQQWTRELEMVVENGCYTLRDTFD 180
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQTD+ ++SL QP A + L I + +GQF WL+E +PL+ AYV+A
Sbjct: 181 DTTILGWMIQTDDTQYSLSQPDIANQSLAIRGARLPEKGQFDGQWLDERDPLQKAYVQA- 239
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
GH++N D Y+YF ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 240 NGHVINQ-DPYQYFTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 298
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA H
Sbjct: 299 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILEKWAEQGYTGKGH 358
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 359 NPAEGLINELAGAWKHSKA 377
>gi|56415081|ref|YP_152156.1| glutathionylspermidine synthetase/amidase [Salmonella enterica
subsp. enterica serovar Paratyphi A str. ATCC 9150]
gi|56129338|gb|AAV78844.1| glutathionylspermidine synthetase/amidase [Salmonella enterica
subsp. enterica serovar Paratyphi A str. ATCC 9150]
Length = 618
Score = 539 bits (1388), Expect = e-151, Method: Composition-based stats.
Identities = 258/379 (68%), Positives = 300/379 (79%), Gaps = 4/379 (1%)
Query: 5 SPNITTHD-PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVE 63
S T+ D PFG+LLGYAPGGVAIYSSDYN+ D + DDAAFRSY+ EYMG+KWQCVE
Sbjct: 2 SKGTTSQDAPFGTLLGYAPGGVAIYSSDYNSLDPWD-DDDAAFRSYIDDEYMGHKWQCVE 60
Query: 64 FARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQ 123
FARR+L+LNYG+VFTDVGMA+EIFSLRFLR+VVND +LPLQAF NG RAPE GALLIWQ
Sbjct: 61 FARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPEAGALLIWQ 120
Query: 124 EGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD 183
+GGEF TGHVA+IT++L +K+RIAEQNVIH+ LP GQQWTREL M V G Y L+DTFD
Sbjct: 121 KGGEFNETGHVAIITQLLDNKIRIAEQNVIHTPLPPGQQWTRELEMVVENGCYTLRDTFD 180
Query: 184 DTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAM 243
DT ILGWMIQTD+ ++SL QP A + L I + +GQF WL+E +PL+ AYV+A
Sbjct: 181 DTTILGWMIQTDDTQYSLSQPDIANQSLAIRGARLPEKGQFDGPWLDESDPLQKAYVQA- 239
Query: 244 KGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWP 303
GH++N D Y+YF ++ESA+ ELI+ATNELHLMYLHATDKVLKDD LL F+IPK+LWP
Sbjct: 240 NGHVINQ-DPYQYFTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWP 298
Query: 304 RLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
RLRLSWQ RR+ ITGRMDFC+DERGLKVYEYN DSASCH EAG IL WA H
Sbjct: 299 RLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILEKWAEQGYTGKGH 358
Query: 364 DPGEGLRNALADTWKHSHA 382
+P EGL N LA WKHS A
Sbjct: 359 NPAEGLINELAGAWKHSKA 377
>gi|90578770|ref|ZP_01234580.1| glutathionylspermidine synthetase/amidase [Vibrio angustum S14]
gi|90439603|gb|EAS64784.1| glutathionylspermidine synthetase/amidase [Vibrio angustum S14]
Length = 625
Score = 503 bits (1295), Expect = e-141, Method: Composition-based stats.
Identities = 234/369 (63%), Positives = 281/369 (76%), Gaps = 1/369 (0%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG+LLGYAPGG+AIYSSDY+T D EY DD+A RSY+ GEYMG KWQCVEFARR+LY+N
Sbjct: 11 PFGTLLGYAPGGIAIYSSDYSTIDENEYTDDSAMRSYVHGEYMGMKWQCVEFARRFLYIN 70
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
YG+VFTDVGMAYEIFSLRFLRQVVND +LPL AFANG +AP G+LLIWQ+GGEF+ TG
Sbjct: 71 YGLVFTDVGMAYEIFSLRFLRQVVNDKILPLYAFANGSCQAPIAGSLLIWQKGGEFQETG 130
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEILGWMI 192
HVA+IT+++ +KV IAEQNV + LP GQQWT EL + V G Y ++DTF+D+EILGWM
Sbjct: 131 HVAIITQIIDNKVMIAEQNVTFAPLPLGQQWTSELTLHVKDGCYTIEDTFEDSEILGWMA 190
Query: 193 QTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAMKGHIVNHGD 252
LPQP P+PE L I + +NQ QF+ WL+E +PLE Y +A ++N D
Sbjct: 191 YNIEAHDCLPQPSPSPELLNIQCAYRDNQAQFSTPWLDETDPLELTYQQANSKQLLND-D 249
Query: 253 QYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSWQNR 312
YRYF +SESA+HEL +ATNELHLMYLHATDKVL+DD LL+ F+IPK+LWPRLRLSWQ
Sbjct: 250 IYRYFTISESAEHELAKATNELHLMYLHATDKVLQDDSLLELFDIPKILWPRLRLSWQKH 309
Query: 313 RYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRHDPGEGLRNA 372
R+ +TGR+DFC+ E GLKVYEYN DSASCH EA I+ WA G + P E L N
Sbjct: 310 RHSMLTGRLDFCMTEDGLKVYEYNADSASCHTEACLIIQKWAEQGGDITENSPAEDLLNE 369
Query: 373 LADTWKHSH 381
LA WK+S
Sbjct: 370 LASVWKYSQ 378
>gi|119944984|ref|YP_942664.1| fused glutathionylspermidine amidase and glutathionylspermidine
synthetase [Psychromonas ingrahamii 37]
gi|119863588|gb|ABM03065.1| fused glutathionylspermidine amidase and glutathionylspermidine
synthetase [Psychromonas ingrahamii 37]
Length = 629
Score = 395 bits (1015), Expect = e-108, Method: Composition-based stats.
Identities = 198/387 (51%), Positives = 256/387 (66%), Gaps = 8/387 (2%)
Query: 1 MPDRSPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQ 60
M +SP++ FG+LLGYAPGGVA YSSDY+TA +YP +AFRSY G YMGYKWQ
Sbjct: 1 MNYKSPSV-----FGTLLGYAPGGVAAYSSDYDTASDIKYPKRSAFRSYFNGIYMGYKWQ 55
Query: 61 CVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALL 120
CVEFARR++Y+N G +F DV MAYEIF LR +R + ++LLPLQAF NG K P+ G+LL
Sbjct: 56 CVEFARRWMYINKGTLFDDVAMAYEIFDLRTVRNLATNSLLPLQAFCNGSKSLPQPGSLL 115
Query: 121 IWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVT-AGRYRLQ 179
IW +GGEF TGHVA++TEV DK+RI EQN+ H P G ++RELP T T G Y L+
Sbjct: 116 IWDQGGEFAETGHVAIVTEVFPDKLRIVEQNLDHQIWPEGHSFSRELPATTTEEGEYWLK 175
Query: 180 DTFDDTEILGWMIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAY 239
+F+D ILGWM QT+++ + P + + + + Q +WLN N EAAY
Sbjct: 176 CSFNDATILGWMTQTEDDRDAEPTLETNKQLFNLISRRAKEQPNPQKSWLNVANEDEAAY 235
Query: 240 VKAMKGHIVNH--GDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNI 297
VKAM GH ++ DQYRY+ LSE+AQH L RA NELH +++HATD VL++ LL FN+
Sbjct: 236 VKAMHGHKLSAVTADQYRYYVLSETAQHALQRAANELHALFMHATDYVLENQALLNKFNL 295
Query: 298 PKLLWPRLRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALA 357
P + P++R SW NR + IT R DF + +GLKVYEYN DSASC+ E+ I WA
Sbjct: 296 PVAILPKIRQSWDNRLNELITSRFDFAMTPQGLKVYEYNCDSASCYMESAKIQGKWARHY 355
Query: 358 GLTLRHDPGEGLRNALADTWKHSHAVG 384
G+ D G+ L N L + W+ S A G
Sbjct: 356 GVQEGQDSGKDLFNHLVNAWRKSQAKG 382
>gi|88858189|ref|ZP_01132831.1| bifunctional: glutathionylspermidine amidase (N-terminal);
glutathionylspermidine synthetase (C-terminal)
[Pseudoalteromonas tunicata D2]
gi|88819806|gb|EAR29619.1| bifunctional: glutathionylspermidine amidase (N-terminal);
glutathionylspermidine synthetase (C-terminal)
[Pseudoalteromonas tunicata D2]
Length = 636
Score = 385 bits (990), Expect = e-105, Method: Composition-based stats.
Identities = 194/374 (51%), Positives = 244/374 (65%), Gaps = 3/374 (0%)
Query: 14 FGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLNY 73
FG+LLGYAPG VA YSSDY TA +YP +AFRS+ G YMGYKWQCVEFARRY+Y+N+
Sbjct: 15 FGTLLGYAPGCVAAYSSDYETASKLQYPKRSAFRSHYDGIYMGYKWQCVEFARRYMYINH 74
Query: 74 GMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTGH 133
G +F DV MAY+IF LR +R V + LLP AF NG KR PE G LLIW+EGGEF+ TGH
Sbjct: 75 GYIFDDVAMAYDIFDLRTVRDVKENQLLPFNAFVNGNKRHPEVGCLLIWKEGGEFEETGH 134
Query: 134 VAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTA-GRYRLQDTFDDTEILGWMI 192
VA++TEV VRIAEQNV H+ G + R+L VT G Y + ++ D +ILGWMI
Sbjct: 135 VAIVTEVTEQFVRIAEQNVGHALWSEGANYARQLKAKVTKEGEYWITCSYGDAQILGWMI 194
Query: 193 QTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAMKGHIVNH-- 250
QTD+ E++ P +H+ H +WLN N EAA+V AM GH +
Sbjct: 195 QTDDNEYAEPHNEKNTALFQLHSNHANEITDAKKSWLNIANEDEAAFVDAMGGHYLTSVI 254
Query: 251 GDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSWQ 310
G+Q RYF S+SA+ L ATNELH M++HATD VL+ +LL+ FN+P + P++R SW
Sbjct: 255 GEQTRYFIASQSAETALEYATNELHNMFMHATDYVLEHPELLEKFNLPNSVLPKIRQSWD 314
Query: 311 NRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRHDPGEGLR 370
NR Q IT R DF + + GLKVYEYN DSASC+ E+G + WA G+ HD G+ L
Sbjct: 315 NRLNQLITSRFDFAMTKNGLKVYEYNCDSASCYMESGKVQGKWARHYGINEGHDAGKDLF 374
Query: 371 NALADTWKHSHAVG 384
+A WK SHA G
Sbjct: 375 KDVARAWKKSHAKG 388
>gi|83595052|ref|YP_428804.1| Glutathionylspermidine amidase [Rhodospirillum rubrum ATCC 11170]
gi|83577966|gb|ABC24517.1| Glutathionylspermidine amidase [Rhodospirillum rubrum ATCC 11170]
Length = 642
Score = 383 bits (984), Expect = e-104, Method: Composition-based stats.
Identities = 195/376 (51%), Positives = 251/376 (66%), Gaps = 12/376 (3%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG++LGY PGGVA+YSSDY+T D + PD A+FRS + G+YMG+KWQCVE ARR+LYL
Sbjct: 11 PFGTVLGYGPGGVAVYSSDYDTVDRRALPDRASFRSVIDGQYMGHKWQCVELARRFLYLT 70
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
+G VF D+ MAY+IF LR +R V D LPL++F NG +R PE G+LLIW EGGEF+ TG
Sbjct: 71 HGYVFDDIAMAYDIFRLRTVRVVAEDRHLPLRSFRNGARRWPEAGSLLIWDEGGEFEVTG 130
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTV-TAGRYRLQDTFDDTEILGWM 191
HVAV+TEV AD++R EQNV P+GQ ++RELP V G Y + TF DT ILGW+
Sbjct: 131 HVAVVTEVFADRLRCIEQNVDDRVWPTGQSYSRELPARVDDQGGYHVACTFADTAILGWV 190
Query: 192 IQTDNEEFS-----LPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAMKGH 246
+QT + FS + + P++ T+ A+ G A WL+ P EAAY+ M G
Sbjct: 191 MQTADPLFSEETTEADRQLFVPQRRTVAAK----PGGAPALWLDPAKPDEAAYMAMMGGC 246
Query: 247 IVNH--GDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPR 304
+ + D+ YF +S++A+ EL RATNELH M+L+ATD VL++D LL F +P+ LWPR
Sbjct: 247 ALTNRPADRETYFRISQTAERELKRATNELHAMFLYATDHVLQNDALLAQFMLPQALWPR 306
Query: 305 LRLSWQNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRHD 364
+R SW NRR + ITGR DF + ERGLKVYEYN DSASCH E G + WAA G
Sbjct: 307 IRQSWANRRGRMITGRFDFSMSERGLKVYEYNADSASCHMECGKVQQAWAAYYGCQEGRC 366
Query: 365 PGEGLRNALADTWKHS 380
GE + AL W+ S
Sbjct: 367 SGEDVHGALVAAWRES 382
>gi|152994258|ref|YP_001339093.1| Glutathionylspermidine amidase [Marinomonas sp. MWYL1]
gi|150835182|gb|ABR69158.1| Glutathionylspermidine amidase [Marinomonas sp. MWYL1]
Length = 625
Score = 380 bits (977), Expect = e-104, Method: Composition-based stats.
Identities = 188/375 (50%), Positives = 246/375 (65%), Gaps = 3/375 (0%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG+LLG APG V +YSSDY++AD E P+ A+RSY+ G +MGYKWQCVEFARR+LYLN
Sbjct: 11 PFGTLLGIAPGNVPVYSSDYDSADDNELPNRHAYRSYVDGIFMGYKWQCVEFARRWLYLN 70
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
G +F DV MAY+IF L +R + +++ LPL++F NG R PE GALLIW EGGEF+ TG
Sbjct: 71 KGYIFDDVAMAYDIFRLTSVRLIADESRLPLKSFRNGSLRHPEVGALLIWNEGGEFEVTG 130
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTA-GRYRLQDTFDDTEILGWM 191
HVA++T+VL D++ + EQNV H GQ ++R L V+ G Y L+ ++ D ++GW+
Sbjct: 131 HVAIVTKVLPDRLYLVEQNVGHQVWQEGQDYSRVLDARVSEDGGYWLRCSYGDASVMGWV 190
Query: 192 IQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAMKGHIVNH- 250
IQTD+E S P + H+ N+GQ + WLN NP E A+V M GH +
Sbjct: 191 IQTDDETHSEQIEPDDPALFDLQIRHVPNKGQASRAWLNVANPAEEAFVDMMGGHKLASR 250
Query: 251 -GDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSW 309
D Y+Y ++ESA+ EL RATNELH +++HATD VL++D LL FNIP LWP++ SW
Sbjct: 251 PEDDYKYMVMTESAERELKRATNELHALFMHATDYVLQNDDLLSSFNIPPALWPKIHQSW 310
Query: 310 QNRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRHDPGEGL 369
NRR Q ITGR DF L +G+KVYEYN DSASC+ EAG I WA G L
Sbjct: 311 DNRRNQMITGRFDFSLSSQGIKVYEYNCDSASCYMEAGIIQEKWAKHYGANEGEGSATEL 370
Query: 370 RNALADTWKHSHAVG 384
+ L + WK+S G
Sbjct: 371 VDELIEAWKNSKVKG 385
>gi|77361371|ref|YP_340946.1| bifunctional: glutathionylspermidine amidase (N-terminal);
glutathionylspermidine synthetase (C-terminal)
[Pseudoalteromonas haloplanktis TAC125]
gi|76876282|emb|CAI87504.1| bifunctional: glutathionylspermidine amidase (N-terminal);
glutathionylspermidine synthetase (C-terminal)
[Pseudoalteromonas haloplanktis TAC125]
Length = 622
Score = 370 bits (949), Expect = e-100, Method: Composition-based stats.
Identities = 192/374 (51%), Positives = 251/374 (67%), Gaps = 3/374 (0%)
Query: 14 FGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLNY 73
FG LLGYAPG VA+YSSDY++AD YP+ +A+RSYL G YMGYKWQCVEFARR++YLN+
Sbjct: 10 FGELLGYAPGNVAVYSSDYDSADESIYPNRSAYRSYLDGIYMGYKWQCVEFARRWMYLNH 69
Query: 74 GMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTGH 133
G +F D+ MAY+IF LR +R+V + LPLQAF NG K P+ G+LLIW+EGGEF+ TGH
Sbjct: 70 GYIFDDIAMAYDIFELRSVREVNSQNRLPLQAFKNGAKHHPQVGSLLIWEEGGEFEETGH 129
Query: 134 VAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTA-GRYRLQDTFDDTEILGWMI 192
VA++ EV DK+R+AEQNV H P GQ W REL +T G Y ++ +++D ILGWM
Sbjct: 130 VAIVVEVHPDKIRLAEQNVGHQTWPQGQNWCRELKAKITKDGDYWIECSYNDATILGWMT 189
Query: 193 QTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYVKAMKGHIV--NH 250
QTD E + P + TI + +I + GQ A +WLN N EAAYV M+GH + N
Sbjct: 190 QTDQIEHAEPTTEINTDLFTIKSNYIADTGQAAKSWLNIANDDEAAYVDMMQGHKLTSNA 249
Query: 251 GDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSWQ 310
DQ+ YF +S +AQ + ATNELH +++HATD VL+ +LL+ FN+P+++ ++R SW
Sbjct: 250 EDQHSYFTISHTAQQAIEHATNELHGLFMHATDYVLQHPELLKKFNLPEVVLNKIRQSWD 309
Query: 311 NRRYQTITGRMDFCLDERGLKVYEYNTDSASCHAEAGAILPHWAALAGLTLRHDPGEGLR 370
NR Q IT R DF L GLKVYEYN DSASC+ E+G + WA G+ D G+ L
Sbjct: 310 NRLNQLITSRFDFALTPAGLKVYEYNCDSASCYMESGKVQGKWARHFGVKTGIDAGQDLF 369
Query: 371 NALADTWKHSHAVG 384
L W+ S G
Sbjct: 370 KDLVKAWRKSEVKG 383
>gi|71417579|ref|XP_810600.1| trypanothione synthetase [Trypanosoma cruzi strain CL Brener]
gi|10257417|gb|AAG15408.1|AF283000_1 trypanothione synthetase [Trypanosoma cruzi]
gi|29468076|gb|AAO00722.1| trypanothione synthetase [Trypanosoma cruzi]
gi|70875156|gb|EAN88749.1| trypanothione synthetase, putative [Trypanosoma cruzi]
Length = 647
Score = 172 bits (437), Expect = 3e-41, Method: Composition-based stats.
Identities = 124/386 (32%), Positives = 184/386 (47%), Gaps = 25/386 (6%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG + GYAPGG+ YS+ + + + E RS G + G+K+QCVEFARR+L+
Sbjct: 10 PFGCVQGYAPGGIPAYSNKHESYFSGE-------RSIDGNLFCGFKYQCVEFARRWLFER 62
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
+V DV A IF+L+ + + A NG P +LLI+ ++ G
Sbjct: 63 KSLVLPDVDWAVHIFNLKEVSDARTGKPVRCVAIRNGTAAKPVVDSLLIYPSD-DYSPVG 121
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEI--LGW 190
HVA ITEV VRIA+QN H + ELP+ G + + D +D + LGW
Sbjct: 122 HVAAITEVGDKWVRIADQN--HRFHKWDANYAAELPLIHEKGVWTILDPLEDEVLKPLGW 179
Query: 191 MIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFA-------ANWLNEDNPLEAAYVKAM 243
+ D + + +P+ E L + + +WL+ N EA +
Sbjct: 180 VTFPDTPDRNPNEPLVLHESLHFKRGELPTLRRLTFTPTSREKDWLDLTNEAEAYFADVC 239
Query: 244 KGHIVNHG-DQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLW 302
+ N ++ Y+ ++ + + N+LH M+L AT VL D+LL+ F IP+ W
Sbjct: 240 GIDVKNPKLEKASYYQMNRELYLDCAKYGNQLHQMFLEATKFVLGSDELLRLFCIPEEYW 299
Query: 303 PRLRLSWQNRRYQTITGRMDFCLDE--RGLKVYEYNTDSASCHAEAGAILPHWAALAGLT 360
PRLR SW+ + + ITGR DF DE + K +EYN DSAS E G I WA GL
Sbjct: 300 PRLRHSWETQPH-AITGRFDFAFDEDTQQFKCFEYNADSASTLLECGVIQQKWARSVGLD 358
Query: 361 --LRHDPGEGLRNALADTWKHSHAVG 384
+ G + + L W+ + G
Sbjct: 359 DGTTYSSGSLVSSRLQLAWEMAEVTG 384
>gi|71654931|ref|XP_816076.1| trypanothione synthetase [Trypanosoma cruzi strain CL Brener]
gi|10257419|gb|AAG15409.1|AF283001_1 trypanothione synthetase [Trypanosoma cruzi]
gi|70881179|gb|EAN94225.1| trypanothione synthetase, putative [Trypanosoma cruzi]
Length = 647
Score = 169 bits (428), Expect = 3e-40, Method: Composition-based stats.
Identities = 121/386 (31%), Positives = 184/386 (47%), Gaps = 25/386 (6%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG + GYAPGG+ YS+ + + + E RS G + G+K+QCVEFARR+L+
Sbjct: 10 PFGCVQGYAPGGIPAYSNKHESYFSGE-------RSIDGNLFCGFKYQCVEFARRWLFER 62
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
+V DV A IF+L+ + + A NG P +LLI+ ++ G
Sbjct: 63 KSLVLPDVEWAVHIFNLKEVSDARTGQNVRCVAIRNGTAAKPVADSLLIY-PSDDYSPVG 121
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEI--LGW 190
HVA ITEV + VRIA+QN H + ELP+ G + + D +D + LGW
Sbjct: 122 HVAAITEVGDNWVRIADQN--HRFHKWDANYAAELPLIHEKGVWTILDPLEDEVLRPLGW 179
Query: 191 MIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFA-------ANWLNEDNPLEAAYVKAM 243
+ + + + +P+ E L + + +WL+ N EA +
Sbjct: 180 VTFPETPDRNPNEPLVLHESLHFKRGEVPTLRRLTFTPNSREKDWLDLTNEAEAYFASVC 239
Query: 244 KGHIVNHG-DQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLW 302
+ N ++ Y+ ++ + + N+LH M+L AT V+ D+ L+ F IP+ W
Sbjct: 240 GIDVKNPKVEKASYYQMNRELYLDCTKYGNQLHQMFLEATKFVIGSDEQLRVFRIPEEYW 299
Query: 303 PRLRLSWQNRRYQTITGRMDFCLDE--RGLKVYEYNTDSASCHAEAGAILPHWAALAGLT 360
PRLR SW+ + + ITGR DF DE + K +EYN DSAS E G I WA GL
Sbjct: 300 PRLRHSWETQPH-AITGRFDFAFDEDTQQFKCFEYNADSASTLLECGVIQQKWARSVGLD 358
Query: 361 --LRHDPGEGLRNALADTWKHSHAVG 384
+ G + + L W+ + G
Sbjct: 359 DGTTYSCGSLISSRLQLAWEMAEVTG 384
>gi|16588445|gb|AAL26803.1|AF311782_1 trypanothione synthetase [Trypanosoma cruzi]
Length = 647
Score = 168 bits (426), Expect = 5e-40, Method: Composition-based stats.
Identities = 120/386 (31%), Positives = 184/386 (47%), Gaps = 25/386 (6%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG + GYAPGG+ YS+ + + + E RS G + G+K+QCVEFARR+L+
Sbjct: 10 PFGCVQGYAPGGIPAYSNKHESYFSGE-------RSIDGNLFCGFKYQCVEFARRWLFER 62
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
+V DV A IF+L+ + + A NG P +LLI+ ++ G
Sbjct: 63 KSLVLPDVDWAVHIFNLKEVSDARTGQPVRCVAIRNGTAAKPVVDSLLIY-PSDDYSPVG 121
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEI--LGW 190
HVA ITEV VRIA+QN H + ELP+ G + + D +D + LGW
Sbjct: 122 HVAAITEVGDKWVRIADQN--HRFHKWDANYAAELPLIHEKGVWTILDPLEDEVLKPLGW 179
Query: 191 MIQTDNEEFSLPQPMPAPEKLTIHAEHIENQGQFA-------ANWLNEDNPLEAAYVKAM 243
+ + + + +P+ E L + + +WL+ N EA +
Sbjct: 180 VTFPETPDRNPNEPLVLHESLHFKRGEVPTLRRLTFTPNSREKDWLDLTNEAEAYFAGVC 239
Query: 244 KGHIVNHG-DQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLW 302
+ N ++ Y+ ++ + ++ N+LH M+L AT V+ D+ L+ F+IP+ W
Sbjct: 240 GIDVKNPKVEKASYYQMNRELYLDCVKYGNQLHQMFLEATKFVIGSDEQLRLFHIPEEYW 299
Query: 303 PRLRLSWQNRRYQTITGRMDFCLDE--RGLKVYEYNTDSASCHAEAGAILPHWAALAGLT 360
PRLR W+ + + ITGR DF DE + K +EYN DSAS E G I WA GL
Sbjct: 300 PRLRYLWETQPH-AITGRFDFAFDEDTQQFKCFEYNADSASTLLECGVIQQKWARSVGLD 358
Query: 361 --LRHDPGEGLRNALADTWKHSHAVG 384
+ G + + L W+ + G
Sbjct: 359 DGTTYSSGSLISSRLQLAWEMAGVTG 384
>gi|24528130|emb|CAD23679.1| trypanothione synthetase [Leishmania donovani]
Length = 652
Score = 165 bits (418), Expect = 4e-39, Method: Composition-based stats.
Identities = 136/406 (33%), Positives = 194/406 (47%), Gaps = 45/406 (11%)
Query: 5 SPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEF 64
S N H PFG++ GYAPGGV YS+ ++ + E RS G + G+K+QCVEF
Sbjct: 10 SFNRPGHIPFGAVQGYAPGGVPAYSNKHDHYFSGE-------RSIEGNIFFGFKYQCVEF 62
Query: 65 ARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQE 124
ARR+L G+V DV A IF L+ +R + NG PE ALL++
Sbjct: 63 ARRWLLARKGLVLPDVNWACHIFQLKEVRDAATAESFAVLPVRNGTGTKPEADALLVYPS 122
Query: 125 GGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDD 184
GHV ITEV D V +A+QN + S + +L + G + + D D
Sbjct: 123 TAT-NPVGHVGAITEVGDDYVCVADQNYRFHKWES--SYAYKLKLDHRDGIWTIIDDIDA 179
Query: 185 TEI---LGWMI---QTDNEEFSLPQPM---------PAPEKLTIHAEHIENQGQFAANWL 229
EI LGW+ + + E + P + P P L + E++ ANWL
Sbjct: 180 NEIEIPLGWVTFPGRANRPEGAPPVALHPSLHFNKPPKPYLLRRNFLPTESK----ANWL 235
Query: 230 NEDNPLEAAYVKAMKGHIVNHGDQYRYFALSESAQHEL----IRATNELHLMYLHATDKV 285
+ +NP E +V+ + + + + ES HE I +LH +++ AT +V
Sbjct: 236 DMNNPAERLFVEEFGMDVSRTRLEEKAVSYYES-NHEFHLRCIAYGTQLHDIFMEATAQV 294
Query: 286 LKDDKLLQYFNIPKLLWPRLRLSWQNRRYQT--ITGRMDFCL-DERG-LKVYEYNTDSAS 341
++ D+ L+ F IP+ WPR+R SW +YQ I+GR DF +E G +K +EYN DSAS
Sbjct: 295 IESDEKLRLFAIPEEFWPRIRHSW---KYQQTYISGRFDFAFNNETGEVKCFEYNADSAS 351
Query: 342 CHAEAGAILPHWAALAGLTLRHDPGEGL---RNALADTWKHSHAVG 384
E G I WA GL + G G RN L W +S A G
Sbjct: 352 TLLECGRIQQKWAESVGLDKQGTRGSGFAVERN-LKMAWANSGATG 396
>gi|148283952|gb|ABQ57409.1| trypanothione synthetase [Leishmania amazonensis]
Length = 652
Score = 159 bits (403), Expect = 2e-37, Method: Composition-based stats.
Identities = 135/405 (33%), Positives = 196/405 (48%), Gaps = 43/405 (10%)
Query: 5 SPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEF 64
S N H PFG++ GYAPGGV YS+ ++ + E RS + G+K+QCVEF
Sbjct: 10 SFNKPGHIPFGAVQGYAPGGVPAYSNKHDHYFSGE-------RSIEDNIFFGFKYQCVEF 62
Query: 65 ARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQE 124
ARR+L + G+V DV A IF L+ +R + NG K PE ALL++
Sbjct: 63 ARRWLLVRKGLVLPDVNWACHIFQLKEVRDAATTESFAVLPVRNGTKTKPEADALLVY-P 121
Query: 125 GGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDD 184
+ GHV VITEV D V +A+QN + S + +L + G + + D D
Sbjct: 122 STDANPVGHVGVITEVGDDYVCVADQNYRFHKWES--SYAYKLKLDHRDGIWTIIDDIDA 179
Query: 185 TEI---LGWMI---QTDNEEFSLPQPM---------PAPEKLTIHAEHIENQGQFAANWL 229
EI LGW+ + + E + P + P P L + E++ ANWL
Sbjct: 180 DEIEIPLGWLTFPGRANRPEGAPPVALHPSLHFKEPPKPYLLRRNFLPTESK----ANWL 235
Query: 230 NEDNPLEAAYVKAMKGHIVNHGDQYRYFALSESAQHELIRAT---NELHLMYLHATDKVL 286
+ +NP E +V+ + + + + ES +R +LH +++ AT +V+
Sbjct: 236 DMNNPAERLFVEEFGMDVSRTRLEEKVVSYYESNHEFYLRCVAYGTQLHAIFMEATAQVI 295
Query: 287 KDDKLLQYFNIPKLLWPRLRLSWQNRRYQT--ITGRMDFCL-DERG-LKVYEYNTDSASC 342
+ D+ L+ F IP+ WPR+R SW +YQ I+GR DF +E G +K +EYN DSAS
Sbjct: 296 ESDEKLRLFAIPEEFWPRIRHSW---KYQQTYISGRFDFAFNNETGEVKCFEYNADSAST 352
Query: 343 HAEAGAILPHWAALAGLTLRHDPGEGL---RNALADTWKHSHAVG 384
E G I WA GL + G G RN L W +S A G
Sbjct: 353 LLECGLIQQKWAESVGLDKQGTRGSGFAVERN-LKMAWANSGATG 396
>gi|29468074|gb|AAO00721.1| trypanothione synthetase [Trypanosoma brucei brucei]
Length = 627
Score = 158 bits (399), Expect = 6e-37, Method: Composition-based stats.
Identities = 124/384 (32%), Positives = 176/384 (45%), Gaps = 29/384 (7%)
Query: 11 HDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLY 70
H PFG + GY P GV YS+ ++ + E RS G + G+K+QCVEFARR+LY
Sbjct: 14 HVPFGEIQGYTPCGVPAYSNGHDGFFSGE-------RSIDGNLFCGFKYQCVEFARRWLY 66
Query: 71 LNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKH 130
G+V DV A IF L + +P +NG P +LLI+ E
Sbjct: 67 EAKGLVLPDVNWAAHIFDLTEVHDASTATPVPCVKVSNGTAAKPVADSLLIYAV-NEDAP 125
Query: 131 TGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEI--L 188
GHVAVITEV VRIA+QN H ++ EL + G + ++D + L
Sbjct: 126 WGHVAVITEVGDKWVRIADQN--HRFHKWKGTYSAELLLKHEGGVWTVEDHAAEGIFVPL 183
Query: 189 GWMIQTDNEEFSLPQPM--------PAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYV 240
GW+ + +P+ PEK + + + +WL+ N EA +
Sbjct: 184 GWVTFPSRPNRNPKEPLVLHESLYFKQPEKPFLRRVVFTPENR-KTDWLDLTNEAEAEFY 242
Query: 241 KAMKGHIVNHGDQYR--YFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIP 298
K G G Y Y+ ++ +R +LH +L AT +VL+ D L+ F IP
Sbjct: 243 KTF-GKEATRGGVYESCYYLMNRELYLNCVRYGTQLHSFFLEATKQVLESDDKLRRFRIP 301
Query: 299 KLLWPRLRLSWQNRRYQTITGRMDFCLDE--RGLKVYEYNTDSASCHAEAGAILPHWAAL 356
+ WPR+R SW+ + + ITGR DF DE + K +EYN DSAS E I WA
Sbjct: 302 EEYWPRIRHSWKTQPH-AITGRFDFVFDENTQEFKCFEYNADSASTLLECAVIQEKWANS 360
Query: 357 AGL--TLRHDPGEGLRNALADTWK 378
GL G+ + L W+
Sbjct: 361 VGLDDNATRSSGKFMPQTLVRAWE 384
>gi|84043680|ref|XP_951630.1| trypanothione synthetase [Trypanosoma brucei TREU927]
gi|33348569|gb|AAQ15894.1| trypanothione synthetase, putative [Trypanosoma brucei]
gi|62359762|gb|AAX80193.1| trypanothione synthetase, putative [Trypanosoma brucei]
Length = 627
Score = 158 bits (399), Expect = 6e-37, Method: Composition-based stats.
Identities = 124/384 (32%), Positives = 176/384 (45%), Gaps = 29/384 (7%)
Query: 11 HDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLY 70
H PFG + GY P GV YS+ ++ + E RS G + G+K+QCVEFARR+LY
Sbjct: 14 HVPFGEIQGYTPCGVPAYSNGHDGFFSGE-------RSIDGNLFCGFKYQCVEFARRWLY 66
Query: 71 LNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKH 130
G+V DV A IF L + +P +NG P +LLI+ E
Sbjct: 67 EAKGLVLPDVNWAAHIFDLTEVHDASTATPVPCVKVSNGTAAKPVADSLLIYAV-NEDAP 125
Query: 131 TGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEI--L 188
GHVAVITEV VRIA+QN H ++ EL + G + ++D + L
Sbjct: 126 WGHVAVITEVGDKWVRIADQN--HRFHKWKGTYSAELLLKHEGGVWTVEDHAAEGIFVPL 183
Query: 189 GWMIQTDNEEFSLPQPM--------PAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYV 240
GW+ + +P+ PEK + + + +WL+ N EA +
Sbjct: 184 GWVTFPSRPNRNPKEPLVLHESLYFKQPEKPFLRRVVFTPENR-KTDWLDLTNEAEAEFY 242
Query: 241 KAMKGHIVNHGDQYR--YFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIP 298
K G G Y Y+ ++ +R +LH +L AT +VL+ D L+ F IP
Sbjct: 243 KTF-GKEATRGGVYESCYYLMNRELYLNCVRYGTQLHSFFLEATKQVLESDDKLRRFRIP 301
Query: 299 KLLWPRLRLSWQNRRYQTITGRMDFCLDE--RGLKVYEYNTDSASCHAEAGAILPHWAAL 356
+ WPR+R SW+ + + ITGR DF DE + K +EYN DSAS E I WA
Sbjct: 302 EEYWPRIRHSWKTQPH-AITGRFDFVFDENTQEFKCFEYNADSASTLLECAVIQEKWANS 360
Query: 357 AGL--TLRHDPGEGLRNALADTWK 378
GL G+ + L W+
Sbjct: 361 VGLDDNATRSSGKFMPQTLVRAWE 384
>gi|24474936|emb|CAC87573.1| trypanothione synthetase [Trypanosoma brucei]
Length = 627
Score = 155 bits (393), Expect = 3e-36, Method: Composition-based stats.
Identities = 123/384 (32%), Positives = 175/384 (45%), Gaps = 29/384 (7%)
Query: 11 HDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLY 70
H PFG + GY P GV YS+ ++ + E RS G + G+K+QCVEFARR+LY
Sbjct: 14 HVPFGEIQGYTPCGVPAYSNGHDGFFSGE-------RSIDGNLFCGFKYQCVEFARRWLY 66
Query: 71 LNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKH 130
G+V DV A IF L + +P +NG P +LLI+ E
Sbjct: 67 EAKGLVLPDVNWAAHIFDLTEVHDASTATPVPCVKVSNGTAAKPVADSLLIYAV-NEDAP 125
Query: 131 TGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEI--L 188
GHVAVITEV VRIA+QN H ++ EL + + ++D + L
Sbjct: 126 WGHVAVITEVGDKWVRIADQN--HRFHKWKGTYSAELLLKHEGSVWTVEDHAAEGIFVPL 183
Query: 189 GWMIQTDNEEFSLPQPM--------PAPEKLTIHAEHIENQGQFAANWLNEDNPLEAAYV 240
GW+ + +P+ PEK + + + +WL+ N EA +
Sbjct: 184 GWVTFPSRPNRNPKEPLVLHESLYFKQPEKPFLRRVVFTPENR-KTDWLDLTNEAEAEFY 242
Query: 241 KAMKGHIVNHGDQYR--YFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIP 298
K G G Y Y+ ++ +R +LH +L AT +VL+ D L+ F IP
Sbjct: 243 KTF-GKEATRGGVYESCYYLMNRELYLNCVRYGTQLHSFFLEATKQVLESDDKLRRFRIP 301
Query: 299 KLLWPRLRLSWQNRRYQTITGRMDFCLDE--RGLKVYEYNTDSASCHAEAGAILPHWAAL 356
+ WPR+R SW+ + + ITGR DF DE + K +EYN DSAS E I WA
Sbjct: 302 EEYWPRIRHSWKTQPH-AITGRFDFVFDENTQEFKCFEYNADSASTLLECAVIQEKWANS 360
Query: 357 AGL--TLRHDPGEGLRNALADTWK 378
GL G+ + L W+
Sbjct: 361 VGLDDNATRSSGKFMPQTLVRAWE 384
>gi|51236703|gb|AAT99012.1| trypanothione synthetase [Crithidia fasciculata]
Length = 652
Score = 155 bits (392), Expect = 5e-36, Method: Composition-based stats.
Identities = 125/396 (31%), Positives = 181/396 (45%), Gaps = 41/396 (10%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG + GYAPG + YS+ ++ + E RS + G+K+QCVEFARR+L
Sbjct: 18 PFGEVQGYAPGHIPAYSNKHDHFFSGE-------RSIDDNVFCGFKYQCVEFARRWLLER 70
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
G+V DV A IF L+ ++ +P+ A NG + PE L+I+ + G
Sbjct: 71 KGLVLPDVNWACHIFKLKSVKDAATAEEVPVIAVRNGTEAKPEPDTLIIY-PSSDVNTVG 129
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD--DTEI-LG 189
HV ITEV D V IA+QN + + ++ +L + G + + D D D EI LG
Sbjct: 130 HVGAITEVGDDYVCIADQNYRFHKWEA--SYSYKLKLQHKDGVWTIIDDIDPNDVEIPLG 187
Query: 190 WMI---QTDNEEFSLP---------QPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEA 237
W+ + E + P QP P + E E + ANWL+ ++P E
Sbjct: 188 WVTFPGYENRPEGAAPPALHPSLHFQPPEEPYLVRKTYEPTETK----ANWLDLNDPAEK 243
Query: 238 AYVKAMKGHIVN---HGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQY 294
+V+ + Y+ I +LH ++ AT +V+ DD+ L+
Sbjct: 244 LFVEEFGMDVSRSRLEETTVNYYECDHEFHLRCIAYGTQLHDYFMEATAQVINDDERLRI 303
Query: 295 FNIPKLLWPRLRLSWQNRRYQT--ITGRMDFCLDERG--LKVYEYNTDSASCHAEAGAIL 350
F IP+ LWPR+R SW +YQ I+GR DF + +K +EYN DSAS E G I
Sbjct: 304 FKIPEELWPRMRHSW---KYQQTYISGRFDFAYNNETHQMKCFEYNADSASTLLECGRIQ 360
Query: 351 PHWAALAGLTLRHDPGEG--LRNALADTWKHSHAVG 384
WA GL G G + L W A G
Sbjct: 361 QKWAESVGLDKEGTRGSGWAVERNLRTAWATCGATG 396
>gi|26400865|sp|O60993|TRYS_CRIFA Trypanothione synthetase (Cf-TS)
gi|3004644|gb|AAC39132.1| trypanothione synthetase [Crithidia fasciculata]
Length = 652
Score = 155 bits (391), Expect = 6e-36, Method: Composition-based stats.
Identities = 125/396 (31%), Positives = 181/396 (45%), Gaps = 41/396 (10%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
PFG + GYAPG + YS+ ++ + E RS + G+K+QCVEFARR+L
Sbjct: 18 PFGEVQGYAPGHIPAYSNKHDHFFSGE-------RSIDDNVFCGFKYQCVEFARRWLLER 70
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
G+V DV A IF L+ ++ +P+ A NG + PE L+I+ + G
Sbjct: 71 KGLVLPDVNWACHIFKLKNVKDAATAEEVPVIAVRNGTEAKPEPDTLIIY-PSSDVNTVG 129
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFD--DTEI-LG 189
HV ITEV D V IA+QN + + ++ +L + G + + D D D EI LG
Sbjct: 130 HVGAITEVGDDYVCIADQNYRFHKWEA--SYSYKLKLQHKDGVWTIIDDIDPNDVEIPLG 187
Query: 190 WMI---QTDNEEFSLP---------QPMPAPEKLTIHAEHIENQGQFAANWLNEDNPLEA 237
W+ + E + P QP P + E E + ANWL+ ++P E
Sbjct: 188 WVTFPGYENRPEGAAPPALHPSLHFQPPEEPYLVRKTYEPTETK----ANWLDLNDPAEK 243
Query: 238 AYVKAMKGHIVN---HGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQY 294
+V+ + Y+ I +LH ++ AT +V+ DD+ L+
Sbjct: 244 LFVEEFGMDVSRSRLEETTVNYYECDHEFHLRCIAYGTQLHDYFMEATAQVINDDERLRI 303
Query: 295 FNIPKLLWPRLRLSWQNRRYQT--ITGRMDFCLDERG--LKVYEYNTDSASCHAEAGAIL 350
F IP+ LWPR+R SW +YQ I+GR DF + +K +EYN DSAS E G I
Sbjct: 304 FKIPEELWPRMRHSW---KYQQTYISGRFDFAYNNETHQMKCFEYNADSASTLLECGRIQ 360
Query: 351 PHWAALAGLTLRHDPGEG--LRNALADTWKHSHAVG 384
WA GL G G + L W A G
Sbjct: 361 QKWAESVGLDKEGTRGSGWAVERNLRTAWATCGATG 396
>gi|146091037|ref|XP_001466426.1| trypanothione synthetase [Leishmania infantum JPCM5]
gi|134070788|emb|CAM69145.1| trypanothione synthetase, putative [Leishmania infantum]
Length = 652
Score = 154 bits (389), Expect = 1e-35, Method: Composition-based stats.
Identities = 136/406 (33%), Positives = 194/406 (47%), Gaps = 45/406 (11%)
Query: 5 SPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEF 64
S N H PFG++ GYAPGGV YS+ ++ + E RS G + G+K+QCVEF
Sbjct: 10 SFNRPGHIPFGAVQGYAPGGVPAYSNKHDHYFSGE-------RSIEGNIFFGFKYQCVEF 62
Query: 65 ARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQE 124
ARR+L + G+V DV A IF L+ +R + NG PE ALL++
Sbjct: 63 ARRWLLVRKGLVLPDVNWACHIFQLKEVRDAATAESFAVLPVRNGTGTKPEADALLVYPS 122
Query: 125 GGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDD 184
GHV ITEV D V +A+QN + S + +L + G + + D D
Sbjct: 123 TAT-NPVGHVGAITEVGDDYVCVADQNYRFHKWES--SYAYKLKLDHRDGIWTIIDDIDA 179
Query: 185 TEI---LGWMI---QTDNEEFSLPQPM---------PAPEKLTIHAEHIENQGQFAANWL 229
EI LGW+ + + E + P + P P L + E++ ANWL
Sbjct: 180 DEIEIPLGWVTFPGRANRPEGAPPVALHPSLHFNKPPKPYLLRRNFLPTESK----ANWL 235
Query: 230 NEDNPLEAAYVKAMKGHIVNHGDQYRYFALSESAQHEL----IRATNELHLMYLHATDKV 285
+ NP E +V+ + + + + ES HE I +LH +++ AT +V
Sbjct: 236 DMKNPAERLFVEEFGMDVSRTRLEEKAVSYYES-NHEFHLRCIAYGTQLHDIFMEATAQV 294
Query: 286 LKDDKLLQYFNIPKLLWPRLRLSWQNRRYQT--ITGRMDFCL-DERG-LKVYEYNTDSAS 341
++ D+ L+ F IP+ WPR+R SW +YQ I+GR DF +E G +K +EYN DSAS
Sbjct: 295 IESDEKLRLFAIPEEFWPRIRHSW---KYQQTYISGRFDFAFNNETGEVKCFEYNADSAS 351
Query: 342 CHAEAGAILPHWAALAGLTLRHDPGEGL---RNALADTWKHSHAVG 384
E G I WA GL + G G RN L W +S A G
Sbjct: 352 TLLECGRIQQKWAESVGLDKQGTRGSGFAVERN-LKMAWANSGATG 396
>gi|154339996|ref|XP_001565955.1| trypanothione synthetase, putative [Leishmania braziliensis]
gi|134063273|emb|CAM45478.1| trypanothione synthetase, putative [Leishmania braziliensis]
Length = 652
Score = 154 bits (388), Expect = 1e-35, Method: Composition-based stats.
Identities = 125/401 (31%), Positives = 186/401 (46%), Gaps = 35/401 (8%)
Query: 5 SPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEF 64
S N H PFG+L GYAPGG+ YS+ ++ + E RS G + G+K+QCVEF
Sbjct: 10 SFNRLGHVPFGALQGYAPGGIPAYSNKHDHYFSGE-------RSIEGNFFCGFKYQCVEF 62
Query: 65 ARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQE 124
ARR+L + G+V +V A IF L+ +R + NG +R PE LLI+
Sbjct: 63 ARRWLLVRKGLVLPNVNWACHIFQLKEVRDAATAEGFAVLKVCNGTERKPEADTLLIYSS 122
Query: 125 GGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDD 184
GHV+VITEV D V +A+QN + S + L + G + + D +
Sbjct: 123 TDACP-VGHVSVITEVGDDYVCVADQNYRFHKWES--SYAYRLKLEHKDGIWTIIDDINV 179
Query: 185 TEI---LGWMIQTDNEEFSLPQPMPA----------PEKLTIHAEHIENQGQFAANWLNE 231
+I LGW+ E + P A P+ + + + + NWL+
Sbjct: 180 DDIEIPLGWVTFPGRENRAEGAPPVALHQSLYFSEPPKPYLLRRSFVVEEAK--PNWLDL 237
Query: 232 DNPLEAAYVKAMKGHIVNHGDQYRYFALSESAQHEL----IRATNELHLMYLHATDKVLK 287
++P E +V+ G V+ A + HE I +LH +++ AT +V++
Sbjct: 238 NDPAERLFVEEF-GMDVSRSRLEEMVASYYESNHEFHLRCIAYGTQLHAIFMEATAQVIE 296
Query: 288 DDKLLQYFNIPKLLWPRLRLSWQNRRYQTITGRMDFCLDERG--LKVYEYNTDSASCHAE 345
D+ L+ F IP+ WPR+R SW+ ++ I+GR DF + +K +EYN DSAS E
Sbjct: 297 SDEKLRLFCIPEDFWPRIRHSWKIQQ-TYISGRFDFAFNNETCEIKCFEYNADSASTLLE 355
Query: 346 AGAILPHWAALAGLTLR--HDPGEGLRNALADTWKHSHAVG 384
G I WA GL G + L W S A G
Sbjct: 356 CGRIQQKWAESVGLNKEGTRSSGFAVERNLKMAWASSGATG 396
>gi|73544497|ref|XP_848143.1| trypanothione synthetase [Leishmania major strain Friedlin]
gi|40809640|emb|CAC83968.1| trypanothione synthetase [Leishmania major]
gi|70800094|gb|AAZ09935.1| trypanothione synthetase, putative [Leishmania major strain
Friedlin]
Length = 652
Score = 152 bits (385), Expect = 3e-35, Method: Composition-based stats.
Identities = 131/405 (32%), Positives = 194/405 (47%), Gaps = 43/405 (10%)
Query: 5 SPNITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEF 64
S N H PFG++ GYAPGGV YS+ ++ + E R+ + G+K+QCVEF
Sbjct: 10 SFNKPGHIPFGAVQGYAPGGVPAYSNKHDHYFSGE-------RNIEDNIFFGFKYQCVEF 62
Query: 65 ARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQE 124
ARR+L + G++ DV A IF L+ +R + NG PE ALL++
Sbjct: 63 ARRWLLVRKGLLLPDVNWACHIFQLKEVRDAATTESFAVLQVRNGTTTKPEADALLVY-P 121
Query: 125 GGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDD 184
+ GHV ITEV D V +A+QN + S + +L + G + + D D
Sbjct: 122 STDANPVGHVGTITEVGDDYVCVADQNYRFHKWESSCAY--KLKLDHRDGIWTIIDDIDA 179
Query: 185 TEI---LGWMI---QTDNEEFSLPQPM---------PAPEKLTIHAEHIENQGQFAANWL 229
EI LGW+ + + E + P + P P L + E++ ANWL
Sbjct: 180 DEIEIPLGWLTFPGRANRPEGAPPVALHPSLHFKEPPKPYLLRRNFLPTESK----ANWL 235
Query: 230 NEDNPLEAAYVKAMKGHIVNHGDQYRYFALSESAQHELIRAT---NELHLMYLHATDKVL 286
+ +NP E +V+ + + + + ES +R +LH +++ AT +V+
Sbjct: 236 DMNNPAERLFVEEFGMDVSRTRLEEKVVSYYESNHEFHLRCVAYGTQLHAIFMEATAQVI 295
Query: 287 KDDKLLQYFNIPKLLWPRLRLSWQNRRYQT--ITGRMDFCL-DERG-LKVYEYNTDSASC 342
+ D+ L+ F IP+ WPR+R SW +YQ I+GR DF +E G +K +EYN DSAS
Sbjct: 296 ESDEKLRLFAIPEEFWPRIRHSW---KYQQTYISGRFDFAFNNETGEVKCFEYNADSAST 352
Query: 343 HAEAGAILPHWAALAGLTLRHDPGEGL---RNALADTWKHSHAVG 384
E G I WA GL + G G RN L W +S A G
Sbjct: 353 LLECGLIQQKWAESVGLDKQDTRGSGFAVERN-LKMAWANSGATG 396
>gi|26394307|sp|P90518|GSP_CRIFA Glutathionylspermidine synthase
gi|10947099|gb|AAC48361.2| glutathionylspermidine synthetase [Crithidia fasciculata]
Length = 719
Score = 110 bits (274), Expect = 2e-22, Method: Composition-based stats.
Identities = 112/376 (29%), Positives = 160/376 (42%), Gaps = 66/376 (17%)
Query: 9 TTHDPFGSLLGYAPGGVAIYS-------SDYNTADAQEYPDDAAFRSYLGGE---YMGYK 58
T PF L+G P GV + S S+ + A P + R + MG K
Sbjct: 17 TAEVPFDELIGVTPDGVPVISNGNEAHFSNLESITAACLPLSSFERKAPCKQPYRKMGVK 76
Query: 59 WQCVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKR---APE 115
WQCVEF RRYL + T + A E++ L V D P++ K AP
Sbjct: 77 WQCVEFVRRYLASRKAVWMTSLCTAEEVWREENLFVDVRDGR-PVEVVRTPNKSTGPAPA 135
Query: 116 CGALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPM-TVTAG 174
+++W EG E GHVA++TEV A VR+AEQN + P ++RE+ M T +G
Sbjct: 136 VADIVVWGEGPETPF-GHVAIVTEVCASCVRVAEQNQGFEKWPEDVPFSREIAMRTTESG 194
Query: 175 RYRLQDTFDDTEILGWM-IQTDNEEFS-----------------LPQPMPAPEKLTIHAE 216
L D+ +LGW+ +Q F L QP P +
Sbjct: 195 EVEL---LDEDPLLGWVTVQAPFYNFDDGDLADSFRLVVGQGQILRQPFP---------K 242
Query: 217 HIENQGQFAANWLNE----DNPLEAAYV---KAMKGHIVNHGD-QYRYFALSESAQHELI 268
H++ WLN D L+ + V +G GD ++ L L
Sbjct: 243 HVD------VPWLNTGEECDTILKHSLVVDGNMGEGAHAEEGDVPGAFYFLDYDMFCRLG 296
Query: 269 RATNELHLMYLHATDKVLKDDK----LLQYFNIPKLLWPRLRLSWQNRRYQTITGRMDFC 324
RA + LH + + AT KVL+D + L YF +P + P LR SW+ + GR DF
Sbjct: 297 RAASSLHRIAMAATAKVLEDPESTHLLEHYFGVPPEIQPLLRRSWE--MTPPMGGRFDFG 354
Query: 325 LDERGLKVYEYNTDSA 340
D + + + EYN DS+
Sbjct: 355 YDGKNVVMLEYNCDSS 370
>gi|146089219|ref|XP_001466279.1| glutathionylspermidine synthase [Leishmania infantum JPCM5]
gi|134070381|emb|CAM68719.1| glutathionylspermidine synthase, putative [Leishmania infantum]
Length = 719
Score = 101 bits (251), Expect = 1e-19, Method: Composition-based stats.
Identities = 104/373 (27%), Positives = 164/373 (43%), Gaps = 68/373 (18%)
Query: 13 PFGSLLGYAPGGVAIYSS--DYNTADAQEY-PDDAAFRSY-------LGGEYMGYKWQCV 62
PF ++G P GV + S+ +++ + + P A S+ + + +G KWQCV
Sbjct: 21 PFDQVIGITPDGVPVISNGNEFHFTNLESVTPFYQALCSFDRKAPVTVPYKKLGVKWQCV 80
Query: 63 EFARRYLYLNYGMVFTDVGMAYEIFSLR--FLRQVVNDALLPLQAFANGGK-RAPECGAL 119
EFARRYL + + +A +++ F+R V + + AN AP +
Sbjct: 81 EFARRYLASRKAVWTASMPIAADMWRAETPFVR-VQDGTPVEFTRIANRSHGPAPAMSDI 139
Query: 120 LIWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMT-VTAGRYRL 178
++W + E GHVAV+TEVL + VR+AEQN R P G ++RE+P+ +AG
Sbjct: 140 IVWGQSEETPF-GHVAVVTEVLPEAVRVAEQNQGFERWPQGMLYSREIPVQRSSAGTVEF 198
Query: 179 QDTFDDTEILGWM-IQTDNEEFS-----------------LPQPMPAPEKLTIHAEHIEN 220
D+ +LGW+ + +F + QP P +H+E
Sbjct: 199 ---VDEDPVLGWVTLHCPYYDFRDGDLADKFLIVTGPGCIVRQPFP---------KHVE- 245
Query: 221 QGQFAANWLNEDNPLEAAYVKAMKGHIVNHGDQYR---------YFALSESAQHELIRAT 271
WL + + Y+K N GD R ++ L + L RA
Sbjct: 246 -----LPWLQPEERCDF-YLKRSLAIGGNVGDDARAKECDVPSAFYFLDYNIWCRLGRAA 299
Query: 272 NELHLMYLHATDKVLKDDK----LLQYFNIPKLLWPRLRLSWQNRRYQTITGRMDFCLDE 327
+ LH + + AT +VL D L YF +P + P LR SW+ ++GR DF D
Sbjct: 300 HSLHRIAMTATAQVLDDADSAYLLEHYFGLPPEIHPLLRRSWE--MMPPMSGRFDFGYDG 357
Query: 328 RGLKVYEYNTDSA 340
+ + EYN DS+
Sbjct: 358 NKVAMLEYNCDSS 370
>gi|71667801|ref|XP_820846.1| glutathionylspermidine synthase [Trypanosoma cruzi strain CL
Brener]
gi|60684549|gb|AAX34340.1| glutathionylspermidine synthetase [Trypanosoma cruzi]
gi|70886207|gb|EAN98995.1| glutathionylspermidine synthase, putative [Trypanosoma cruzi]
Length = 719
Score = 100 bits (249), Expect = 2e-19, Method: Composition-based stats.
Identities = 108/405 (26%), Positives = 181/405 (44%), Gaps = 55/405 (13%)
Query: 9 TTHDPFGSLLGYAPGGVAIYSS---DYNTADAQEYPD----DAAFRSYLGGEY--MGYKW 59
T H FG ++G GV ++S+ + + PD +AA + + G + +GYKW
Sbjct: 15 TEHVSFGGVIGVTDCGVPVFSNGEKKFFSERISFAPDCKRVEAAAPTTVIGTHDTLGYKW 74
Query: 60 QCVEFARRYLYLNYGMVFTDVGMAYEIFSL-RFLRQVVNDALLPLQAFANGGKRA-PECG 117
C+EFARRYL + G+ V A +I+ + + V +P++ +G + P G
Sbjct: 75 LCLEFARRYLLMTKGVWLASVPTAEDIWEIDEIVTSVPIGTPVPVEREKHGDTTSMPSVG 134
Query: 118 ALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTR-------ELPMT 170
LL+W + + GH+AV+T V + V +AEQN R G+ ++R E +T
Sbjct: 135 DLLVWSRTEDSPY-GHLAVVTHVSDNGVCVAEQNYEFKRWQEGKNYSRRFDCEKREDGVT 193
Query: 171 VTAGRYRLQDTFDDTEILGW-MIQTDNEEFSLPQPMPAPEKLTIHAEHIEN---QGQFAA 226
V G +T +LGW +I+ +FSL +P + I HI +
Sbjct: 194 VFVG---------ETHLLGWVIIKAPPYDFSLGD-LPDKYRHIIGPGHIVRRHLEKDVLL 243
Query: 227 NWLNEDNPLEAAYVKAM------------KGHIVNHGDQYRYFALSESAQHELIRATNEL 274
WLN + +++ + H V G ++ + AT L
Sbjct: 244 PWLNPSQRCDFFLKRSLTVGGYMGEDAVAEAHSVPDG----FYMMDYDMWCRFRFATKNL 299
Query: 275 HLMYLHATDKVL--KDDK--LLQYFNIPKLLWPRLRLSWQNRRYQTITGRMDFCLDERGL 330
H + + AT +L +D + L+QYF +PK L +LR S++ ++ GR DF D + +
Sbjct: 300 HAVAVEATRLILNSRDSEALLVQYFGLPKELHLQLRRSFET--IPSMCGRFDFGYDGKEI 357
Query: 331 KVYEYNTDSASCHAEAGAILPHWAALAGLTLRHDPGEGLRNALAD 375
+ YN DS++ E G +A G+ L G L + +A+
Sbjct: 358 IMLAYNCDSSAAMLECGDTQEKFARHYGVELGTSTGSFLYSRIAN 402
>gi|153876761|ref|ZP_02003917.1| D-alanyl-glycyl endopeptidase-like protein [Beggiatoa sp. PS]
gi|152066775|gb|EDN66083.1| D-alanyl-glycyl endopeptidase-like protein [Beggiatoa sp. PS]
Length = 227
Score = 97.4 bits (241), Expect = 2e-18, Method: Composition-based stats.
Identities = 64/185 (34%), Positives = 99/185 (53%), Gaps = 26/185 (14%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
P+G +LG A V YS+ AQ + ++ G Y G KWQCVEFARR+L +
Sbjct: 53 PYGKILGVASSNVVAYSN----CQAQCVIFEPNHKN---GTYTGIKWQCVEFARRWLLTH 105
Query: 73 YGMVFTDVGMAYEIF-SLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHT 131
G+V+ DV +A +++ + F+ +V + L + NG +AP+ G LLI+ + F T
Sbjct: 106 QGVVYGDVDIAADLWHKIDFVSRVADGKQFKLASHLNGSNQAPQVGDLLIYAKA--FFQT 163
Query: 132 GHVAVIT--EVLADKVRIAEQNVIHSRLPSGQQW----TRELPMTVTAGRYRLQDTFDDT 185
GHVAV+T ++ +++AEQN + Q W RE+P+ G+Y L D +
Sbjct: 164 GHVAVVTGVDLKVGIIQVAEQNF------ANQTWEGDYAREIPLIEQEGQYWLLDGY--- 214
Query: 186 EILGW 190
+LGW
Sbjct: 215 -LLGW 218
>gi|71656485|ref|XP_816789.1| trypanothione synthetase [Trypanosoma cruzi strain CL Brener]
gi|70881940|gb|EAN94938.1| trypanothione synthetase, putative [Trypanosoma cruzi]
Length = 236
Score = 93.6 bits (231), Expect = 2e-17, Method: Composition-based stats.
Identities = 54/180 (30%), Positives = 86/180 (47%), Gaps = 11/180 (6%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
P + G+APG + YS+ ++ E R Y+ +MGYKWQCVEF RR+L+
Sbjct: 15 PLHGICGFAPGRIPAYSNGSDSIFTSE-------RHYVQHYFMGYKWQCVEFVRRWLFYR 67
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
G+ A ++ LR ++ V +P Q G + P +L+++ G G
Sbjct: 68 KGLALPQYDFAAQLIHLREVQDVCTGTAVPCQFIPQGSEEPPVADSLIVY-PGSRKNIVG 126
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEILGWMI 192
HV +IT V + V +A+QN ++ E P+ GRY ++D D E GW++
Sbjct: 127 HVGLITHVTSTNVYVADQNRFFHDWGE-DTFSAEFPLECVDGRYYIRDP--DVECRGWIV 183
>gi|71664993|ref|XP_819471.1| trypanothione synthetase [Trypanosoma cruzi strain CL Brener]
gi|70884774|gb|EAN97620.1| trypanothione synthetase, putative [Trypanosoma cruzi]
Length = 236
Score = 92.4 bits (228), Expect = 4e-17, Method: Composition-based stats.
Identities = 54/180 (30%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
P + G+APG + YS+ ++ E R Y+ +MGYKWQCVEF RR+L+
Sbjct: 15 PLHGICGFAPGRIPAYSNGSDSIFTNE-------RHYVQHYFMGYKWQCVEFVRRWLFYR 67
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
G+ A ++ LR ++ V +P Q G + P +L+++ G G
Sbjct: 68 KGLALPQYDFAAQLIHLREVQDVCTGTAVPCQFIPQGSEEPPVADSLIVY-PGSRKNIVG 126
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEILGWMI 192
HV +IT V V +A+QN ++ E P+ GRY ++D D E GW++
Sbjct: 127 HVGLITHVTPTNVYVADQNRFFHDWGE-DTFSAEFPLECVDGRYYIRDP--DVECRGWIV 183
>gi|71665703|ref|XP_819818.1| trypanothione synthetase-like protein [Trypanosoma cruzi strain CL
Brener]
gi|70885137|gb|EAN97967.1| trypanothione synthetase-like protein, putative [Trypanosoma cruzi]
Length = 666
Score = 88.2 bits (217), Expect = 1e-15, Method: Composition-based stats.
Identities = 71/206 (34%), Positives = 107/206 (51%), Gaps = 22/206 (10%)
Query: 54 YMGYKWQCVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANG-GKR 112
Y GY++QCVE+ARR+L L G VF G A EIF ++ L+ + DA L A NG KR
Sbjct: 48 YTGYRYQCVEYARRFLILTTGCVFGSCGGANEIFEMKTLKHIETDAKLDFIAHPNGKSKR 107
Query: 113 APECGALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPS-------GQQW-T 164
P G ++++ + GHV VI+ V KV IAEQN S S G++ +
Sbjct: 108 RPTPGDIIVYPRHSQLLPWGHVGVISYVHNQKVGIAEQNYSFSLFTSPDPGYLGGERCVS 167
Query: 165 RELPMTVTA-GRYRLQD-TFDDTEILGWM-IQTDNEEFSLPQPMPA-PEKLTIHAEHIEN 220
R L + +TA G ++L++ + + LGWM + S+ +P+ A PE+ + A ++
Sbjct: 168 RYLDLELTADGNWQLRERQRNHPDCLGWMSYPRASRRSSIHEPLQAPPEQRRVRATPLDQ 227
Query: 221 QG-----QFAANWLNEDN-PLEAAYV 240
+ +FA L ED P + YV
Sbjct: 228 EDHPCLWRFA---LPEDKFPFRSLYV 250
>gi|72392547|ref|XP_847074.1| trypanothione synthetase, putative [Trypanosoma brucei TREU927]
gi|62175612|gb|AAX69745.1| trypanothione synthetase, putative [Trypanosoma brucei]
gi|70803104|gb|AAZ13008.1| trypanothione synthetase, putative [Trypanosoma brucei]
Length = 237
Score = 82.8 bits (203), Expect = 3e-14, Method: Composition-based stats.
Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 11/179 (6%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
P + GYAPG + YS+ +T + Y +MGYKWQCVEFARR+L L
Sbjct: 16 PLHGVCGYAPGCIPAYSNGTDTTFTYQ-------GHYADNFFMGYKWQCVEFARRWLLLR 68
Query: 73 YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTG 132
G+ A + +R + ++P + + G P AL+++ G G
Sbjct: 69 KGLALPQYDFAAHLIHMREVCDAETGEVVPCKFVSQGSPEPPVADALIVY-PGTRENIFG 127
Query: 133 HVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQDTFDDTEILGWM 191
HV VIT V V +A+QN G+ + E P+ G+Y ++D E GW+
Sbjct: 128 HVGVITHVTDALVGVADQNRFFHDW-DGRPYAAEFPLECVDGQYFIRDPL--VECRGWV 183
>gi|118361736|ref|XP_001014096.1| Glutathionylspermidine synthase family protein [Tetrahymena
thermophila SB210]
gi|89295863|gb|EAR93851.1| Glutathionylspermidine synthase family protein [Tetrahymena
thermophila SB210]
Length = 1547
Score = 81.6 bits (200), Expect = 9e-14, Method: Composition-based stats.
Identities = 47/100 (47%), Positives = 63/100 (63%), Gaps = 3/100 (3%)
Query: 257 FALSESAQHELIRATNELHLMYLHATDKVLKDDKLL-QYFNIPKLLWPRLRLSWQNRRYQ 315
+ LSE+ LI+ T+ELH M L ATD+VLKDD LL + F+IPK ++P +R SW+NR+
Sbjct: 1074 YQLSENIFTNLIKTTHELHNMCLEATDRVLKDDLLLKEVFDIPKDMFPIIRKSWENRQLD 1133
Query: 316 TITGRMDFCLDERG-LKVYEYNTDSASCHAEAGAILPHWA 354
++ R DF L + G L E N D+ SC EAG WA
Sbjct: 1134 LLS-RYDFILGKNGQLYFLEVNGDTPSCIIEAGQAQKLWA 1172
>gi|145536403|ref|XP_001453929.1| hypothetical protein [Paramecium tetraurelia]
gi|124421662|emb|CAK86532.1| unnamed protein product [Paramecium tetraurelia]
Length = 195
Score = 78.6 bits (192), Expect = 7e-13, Method: Composition-based stats.
Identities = 55/171 (32%), Positives = 87/171 (50%), Gaps = 15/171 (8%)
Query: 28 YSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLNYGMVFTDVGMAYEIF 87
+ S+Y T D ++ F + + +++QCVEFARRYL G+VF DVG AY IF
Sbjct: 28 FRSNYVTFDNRQVYTGVRFYTI----HYYFRFQCVEFARRYLIQTKGVVFGDVGCAYHIF 83
Query: 88 SLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTGHVAVITEVLADKVRI 147
L + +V Q+ G P+ G L+I+Q+ G+ + GHVAV+T V + + +
Sbjct: 84 DLNTVTDLVTQQQRQFQSIPQGSSIPPKKGDLVIYQKSGK-QWWGHVAVVTNVDGNLIDL 142
Query: 148 AEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQD-------TFDDTE-ILGW 190
AEQN + Q + R++ + +Y L + +D E I+GW
Sbjct: 143 AEQN--YDEDWDSQSYARQVLLKKEGDKYFLTNIRQYKPHAWDLNEVIIGW 191
>gi|154344268|ref|XP_001568078.1| D-alanyl-glycyl endopeptidase-like protein; cysteine peptidase,
Clan CA, family C51,putative [Leishmania braziliensis]
gi|134065412|emb|CAM40843.1| D-alanyl-glycyl endopeptidase-like protein; cysteine peptidase,
Clan CA, family C51,putative [Leishmania braziliensis]
Length = 334
Score = 77.8 bits (190), Expect = 1e-12, Method: Composition-based stats.
Identities = 70/213 (32%), Positives = 104/213 (48%), Gaps = 45/213 (21%)
Query: 13 PFGSLLGYAPG--GVAIYSSDY----------------NTADAQEYPDDAAFRSYLGGEY 54
PFG++LG G G + + DY N EY + F
Sbjct: 130 PFGAILGVYDGVFGYSNCNDDYESTKYKYVNLMVPVLNNKTGKVEYTSKSFF-------- 181
Query: 55 MGYKWQCVEFARRYLYLN---YGMVFTDVGMAYEIFSLRFLRQVVN-DALLPLQAFANGG 110
G +WQCVEFARR+ L+ G F V A +I++L F+R V N A LPLQ ++NGG
Sbjct: 182 TGLEWQCVEFARRFWMLSGKPEGAYFDSVVGAADIWNLSFVRLVSNTSATLPLQKYSNGG 241
Query: 111 K-----RAPECGALLIWQ-EGGEFKHTGHVAVITEV---LADKVRIAEQNVIHSR-LPSG 160
+ +AP G ++I+ +GG F + GHVAVIT+V + + +AEQN + +
Sbjct: 242 RLSDGLQAPAPGDIIIYPVQGGGFPY-GHVAVITKVDMAVNGAIYVAEQNWGSAMWVDPH 300
Query: 161 QQWTRELPMT--VTAGRYRLQDTFDDTEILGWM 191
++R +P+ +T L D + I+GWM
Sbjct: 301 HNYSRRIPLMYDMTTSSVTLNDP--NGIIIGWM 331
>gi|145526691|ref|XP_001449151.1| hypothetical protein [Paramecium tetraurelia]
gi|124416728|emb|CAK81754.1| unnamed protein product [Paramecium tetraurelia]
Length = 818
Score = 76.6 bits (187), Expect = 3e-12, Method: Composition-based stats.
Identities = 62/200 (31%), Positives = 98/200 (49%), Gaps = 26/200 (13%)
Query: 11 HDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGE--------YMGYKWQCV 62
+ P+G+++G P GV YS+ D + + ++ Y E Y+G+K+QCV
Sbjct: 616 YPPWGTVMG-QPFGVPAYSNIGFVFDRNKIHE---YQCYWPKEETGLARDVYIGFKYQCV 671
Query: 63 EFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVN-DALLPLQAFANGGKRAPECGALLI 121
E+ARR+L L + F DV A+ I++L + + P F NG K P+ G ++I
Sbjct: 672 EYARRFLTLYFKAAFQDVPHAHHIWALETIEDCTKEEGTFPFVNFPNGSKEPPKIGDIII 731
Query: 122 WQEGGEFKHTGHVAVITEV-LADK-VRIAEQNVIHSRLPSGQQWTRELPMTVTAGRY--- 176
+ E + GHV VI V L +K V IAEQN + ++ R L + + G+Y
Sbjct: 732 YPYSKE-QRFGHVGVIINVNLEEKIVDIAEQNYEEAGWEC-PEYARRLILKIQDGQYFIT 789
Query: 177 --RLQDTFDD----TEILGW 190
R+ +D+ EI GW
Sbjct: 790 NKRIGKPYDNWDAKEEIFGW 809
>gi|145497204|ref|XP_001434591.1| hypothetical protein [Paramecium tetraurelia]
gi|124401718|emb|CAK67194.1| unnamed protein product [Paramecium tetraurelia]
Length = 220
Score = 76.3 bits (186), Expect = 4e-12, Method: Composition-based stats.
Identities = 46/125 (36%), Positives = 67/125 (53%), Gaps = 12/125 (9%)
Query: 6 PNITTHDPFGSLLGYAPGGVAIYSS---DYNTADAQEY-----PDDAAFRSYLGGEYMGY 57
P H P+GS +G A GGV YS+ +Y+ Y +++ R + +MGY
Sbjct: 14 PMNKQHPPWGSQIGVAHGGVIGYSNCEPNYDITKVHLYEVHYKKEESGLRCDI---FMGY 70
Query: 58 KWQCVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDA-LLPLQAFANGGKRAPEC 116
K+QCVEFARR+ LNY +FTD+ A +I+ L + + +A PL F GG P+
Sbjct: 71 KYQCVEFARRFFVLNYKTMFTDIQKAPDIWDLETVEDLTKEAGTFPLVGFKQGGPEPPKF 130
Query: 117 GALLI 121
G LL+
Sbjct: 131 GDLLL 135
>gi|118361730|ref|XP_001014093.1| Glutathionylspermidine synthase family protein [Tetrahymena
thermophila SB210]
gi|89295860|gb|EAR93848.1| Glutathionylspermidine synthase family protein [Tetrahymena
thermophila SB210]
Length = 561
Score = 74.7 bits (182), Expect = 1e-11, Method: Composition-based stats.
Identities = 45/100 (45%), Positives = 59/100 (59%), Gaps = 3/100 (3%)
Query: 257 FALSESAQHELIRATNELHLMYLHATDKVLKDDKLL-QYFNIPKLLWPRLRLSWQNRRYQ 315
+ LSE LI+ T+ELH M L ATD L DD LL + F+IPK ++P +R SW+NR+
Sbjct: 89 YQLSEKLFTNLIKTTHELHNMCLEATDIALNDDLLLKEVFDIPKDMFPIIRKSWENRQLD 148
Query: 316 TITGRMDFCLDERG-LKVYEYNTDSASCHAEAGAILPHWA 354
++ R DF L + G L E N D+ SC EAG WA
Sbjct: 149 LLS-RYDFILGKNGQLYFLEVNGDTPSCIIEAGQAQKLWA 187
>gi|145500608|ref|XP_001436287.1| hypothetical protein [Paramecium tetraurelia]
gi|124403426|emb|CAK68890.1| unnamed protein product [Paramecium tetraurelia]
Length = 205
Score = 74.3 bits (181), Expect = 1e-11, Method: Composition-based stats.
Identities = 51/149 (34%), Positives = 77/149 (51%), Gaps = 14/149 (9%)
Query: 54 YMGYKWQCVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVN-DALLPLQAFANGGKR 112
Y+G+K+QCVE+ARR+L L + FTD+ A+ I++L + + P + NG K
Sbjct: 50 YIGFKYQCVEYARRFLTLKFKAAFTDIPHAHNIWALDIIEDCTKEEGTFPFVNYPNGSKE 109
Query: 113 APECGALLIWQEGGEFKHTGHVAVITEV-LADK-VRIAEQNVIHSRLPSGQQWTRELPMT 170
P+ G L+I+ E + GHV VI V L +K V I EQN + ++ R L M
Sbjct: 110 PPQFGDLIIYPYSKE-QRFGHVGVILNVNLEEKYVDIGEQNYEEAGWEC-PEYARRLIMK 167
Query: 171 VTAGRY-----RLQDTFD----DTEILGW 190
+ G+Y R+ +D + EI GW
Sbjct: 168 IENGQYFITNKRIGKPYDNWDINEEIFGW 196
>gi|145494796|ref|XP_001433392.1| hypothetical protein [Paramecium tetraurelia]
gi|124400509|emb|CAK65995.1| unnamed protein product [Paramecium tetraurelia]
Length = 237
Score = 73.9 bits (180), Expect = 2e-11, Method: Composition-based stats.
Identities = 53/166 (31%), Positives = 79/166 (47%), Gaps = 15/166 (9%)
Query: 14 FGSLLGYAPGGVAIYSSDYNT---ADAQEY--PDDAAFRSYLGGEYMGYKWQCVEFARRY 68
FG ++G + YS +T AD Y P ++ + Y+G ++QCV +AR Y
Sbjct: 36 FGVVIGQG-NKIPAYSCQNDTQHIADLPHYLQPQESGLNQTV---YVGMRYQCVHYARYY 91
Query: 69 LYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEF 128
L Y F D+ A +IF L F +N + F NGGK P G L+IW + +
Sbjct: 92 WILKYASAFPDIDTADQIFDLDFAYDYLNGGKRQILQFKNGGKEKPLPGDLVIWNKSEPY 151
Query: 129 KHTGHVAVITEVLADK----VRIAEQNVIHSRLPSGQQWTRELPMT 170
GHVAV+ +V + V I EQN + + Q + R+L +T
Sbjct: 152 YPFGHVAVVLDVQLSEDHPFVTIGEQN--YDDIWDSQYYARKLQVT 195
>gi|145494794|ref|XP_001433391.1| hypothetical protein [Paramecium tetraurelia]
gi|124400508|emb|CAK65994.1| unnamed protein product [Paramecium tetraurelia]
Length = 264
Score = 73.2 bits (178), Expect = 3e-11, Method: Composition-based stats.
Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 6/103 (5%)
Query: 54 YMGYKWQCVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRA 113
Y+G K+QCV +ARR+ NY F V A +IF L+ + L+ F NGG
Sbjct: 102 YIGQKYQCVHYARRFWITNYNTTFGSVERAEQIFDLQEAYNFDIKQNISLKKFQNGGVEP 161
Query: 114 PECGALLIWQEG-GEFKHTGHVAVITEVLADK----VRIAEQN 151
P+ G LLIWQ+ GEF + GHVAV+ + A+ + IAEQN
Sbjct: 162 PKVGDLLIWQKDEGEFPY-GHVAVVISIEAESAYPHILIAEQN 203
>gi|145493617|ref|XP_001432804.1| hypothetical protein [Paramecium tetraurelia]
gi|124399918|emb|CAK65407.1| unnamed protein product [Paramecium tetraurelia]
Length = 197
Score = 73.2 bits (178), Expect = 3e-11, Method: Composition-based stats.
Identities = 61/197 (30%), Positives = 94/197 (47%), Gaps = 33/197 (16%)
Query: 14 FGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGE--------YMGYKWQCVEFA 65
+GSLLG A V YS N ++ +++S L E ++G K+QCVE+A
Sbjct: 9 WGSLLGEA-HNVKAYS---NVGIHYDHSKWNSYKSILKKEESGLTKDVFLGVKYQCVEYA 64
Query: 66 RRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEG 125
RR+L +N+ F D+ A EI+ L ++ + F N G + P+ G L+I+
Sbjct: 65 RRFLVINFAAAFKDINCADEIYKLNYVEDLTT-------TFPNKGNQPPQVGDLIIYPRT 117
Query: 126 GEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYR-------L 178
+ + GHVAVI EV V +AEQN S + + R+L + G+Y L
Sbjct: 118 QK-QPYGHVAVIVEVGMGYVCVAEQNYEDSGWIK-KNYARKLKVNQVNGQYEITQVRVGL 175
Query: 179 QDTFD-----DTEILGW 190
+ F + +ILGW
Sbjct: 176 EHQFQYWWDRNEQILGW 192
>gi|145542015|ref|XP_001456695.1| hypothetical protein [Paramecium tetraurelia]
gi|124424508|emb|CAK89298.1| unnamed protein product [Paramecium tetraurelia]
Length = 220
Score = 72.8 bits (177), Expect = 4e-11, Method: Composition-based stats.
Identities = 44/120 (36%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Query: 8 ITTHDPFGSLLGYAPGGVAIYSS-DYNTADAQEYPDDAAFRSYLGGE----YMGYKWQCV 62
I H P+GS +G A GGV YS+ + N + Y + ++ G +MGYK+QCV
Sbjct: 16 IKQHPPWGSQIGVAHGGVIGYSNCEPNYDRTRFYLYEIHYKKEESGLRCDIFMGYKYQCV 75
Query: 63 EFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDA-LLPLQAFANGGKRAPECGALLI 121
EFARR+ LNY +FTD+ A +I++L + + ++ P F GG P+ G LL+
Sbjct: 76 EFARRFFVLNYKTMFTDIQKAPDIWNLETVEDLSKESGTFPFVGFKQGGTEPPKFGDLLL 135
>gi|118348648|ref|XP_001007799.1| Glutathionylspermidine synthase family protein [Tetrahymena
thermophila SB210]
gi|89289566|gb|EAR87554.1| Glutathionylspermidine synthase family protein [Tetrahymena
thermophila SB210]
Length = 603
Score = 70.9 bits (172), Expect = 2e-10, Method: Composition-based stats.
Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 3/100 (3%)
Query: 257 FALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQ-YFNIPKLLWPRLRLSWQNRRYQ 315
+ +SE+ ++I+ T+ELH M L ATD+ +KDD++LQ F+IP+ + P +R SWQ+R+
Sbjct: 85 YRISENKFKQIIQTTHELHNMCLQATDEAIKDDEILQNVFDIPQDMIPIIRKSWQDRQLD 144
Query: 316 TITGRMDFCLDERG-LKVYEYNTDSASCHAEAGAILPHWA 354
+ R DF L + G L E N D+ S EAG WA
Sbjct: 145 -LLARYDFLLGKEGELYFLEVNGDTPSSIIEAGPAQKIWA 183
>gi|71424221|ref|XP_812721.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma cruzi
strain CL Brener]
gi|70877537|gb|EAN90870.1| D-alanyl-glycyl endopeptidase-like protein, putative [Trypanosoma
cruzi]
Length = 310
Score = 70.1 bits (170), Expect = 2e-10, Method: Composition-based stats.
Identities = 64/196 (32%), Positives = 95/196 (48%), Gaps = 25/196 (12%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
P+G++LG A G V YS+ D++ + ++ + G KW C+EFARRY L
Sbjct: 125 PYGAILG-AAGDVFAYSNCIRNYDSKSRNNVSS-----QNKESGLKWDCMEFARRYWMLR 178
Query: 73 YGMV---FTDVGMAYEIFSLRFLRQVVNDALLPLQAFANG-----GKRAPECGALLIWQE 124
V F V A +I++L F+R +++ + PL + NG G AP G LLI+
Sbjct: 179 GTPVRATFDSVVGAADIWALNFVR-LLDGSKTPLLKYPNGLPRRDGGSAPRAGDLLIYPR 237
Query: 125 GGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSG-QQWTRELPMTVTAGRYRLQDTFD 183
E GHVAV+ V + V +AEQN + P +RE+ M + + D ++
Sbjct: 238 QREDFPFGHVAVVVGVTKNSVLVAEQNWDNKMWPGPYHNHSREIRMLYSP----IHDAYN 293
Query: 184 DTE-----ILGWMIQT 194
TE I GWM T
Sbjct: 294 ITEEENIIIDGWMRYT 309
>gi|145509885|ref|XP_001440881.1| hypothetical protein [Paramecium tetraurelia]
gi|124408109|emb|CAK73484.1| unnamed protein product [Paramecium tetraurelia]
Length = 265
Score = 70.1 bits (170), Expect = 3e-10, Method: Composition-based stats.
Identities = 50/136 (36%), Positives = 71/136 (52%), Gaps = 11/136 (8%)
Query: 25 VAIYSS--DYNTADAQ--EYPDDAAFRSYLGGE-YMGYKWQCVEFARRYLYLNYGMVFTD 79
V YS+ D N D + E+ +D+ + G E Y+G K+QCV+FARR+ ++Y F
Sbjct: 71 VPAYSNFGDPNVLDTKKDEFLEDS--KRIFGEEVYVGQKYQCVQFARRFWIVHYNSTFGS 128
Query: 80 VGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTGHVAVITE 139
V A +IF L+ L L+ F NG P+ G LLIW++ E GHVA++
Sbjct: 129 VNYAEQIFYLQQAYNFNTKQSLQLKKFQNGDIHPPQQGDLLIWKKDEEEFPYGHVAIVIS 188
Query: 140 VLADK----VRIAEQN 151
V + V IAEQN
Sbjct: 189 VEMESSYPHVLIAEQN 204
>gi|68130089|emb|CAJ09397.1| trypanothione synthetase-like protein [Leishmania major]
Length = 749
Score = 68.6 bits (166), Expect = 8e-10, Method: Composition-based stats.
Identities = 39/100 (39%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
Query: 54 YMGYKWQCVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGG--K 111
Y G+++QCVE+ARR+L L G VF + G A EI+++ + V A L N G
Sbjct: 47 YTGFRYQCVEYARRFLLLTTGCVFANCGRASEIYAMDHITHVETGAQYTLHRHHNDGTAT 106
Query: 112 RAPECGALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQN 151
+ P G ++I+ E GHV VI+ V ++V IAEQN
Sbjct: 107 QKPAPGDIIIYPYHPELTPWGHVGVISFVDDNRVGIAEQN 146
>gi|71399874|ref|XP_802893.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma cruzi
strain CL Brener]
gi|70865220|gb|EAN81447.1| D-alanyl-glycyl endopeptidase-like protein, putative [Trypanosoma
cruzi]
Length = 372
Score = 67.8 bits (164), Expect = 1e-09, Method: Composition-based stats.
Identities = 55/153 (35%), Positives = 76/153 (49%), Gaps = 19/153 (12%)
Query: 56 GYKWQCVEFARRYLYLNYGMV---FTDVGMAYEIFSLRFLRQVVNDALLPLQAFANG--- 109
G +WQCVEFARRY L V F V A +I++L F+R +++ + PL + NG
Sbjct: 224 GLEWQCVEFARRYWMLRGTPVRATFDSVVGAADIWALNFVR-LLDGSKTPLLKYPNGLPR 282
Query: 110 --GKRAPECGALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSG-QQWTRE 166
G AP G LLI+ E GHVAV+ V + V +AEQN + P +RE
Sbjct: 283 RDGGSAPRAGDLLIYPRQREDFPFGHVAVVVGVTKNSVLVAEQNWDNKMWPGPYHNHSRE 342
Query: 167 LPMTVTAGRYRLQDTFDDTE-----ILGWMIQT 194
+ M + + D ++ TE I GWM T
Sbjct: 343 IRMLYSP----IHDAYNITEEENIIIDGWMRYT 371
>gi|146105250|ref|XP_001470013.1| trypanothione synthetase-like protein [Leishmania infantum]
gi|134074383|emb|CAM73134.1| trypanothione synthetase-like protein [Leishmania infantum]
Length = 749
Score = 67.8 bits (164), Expect = 1e-09, Method: Composition-based stats.
Identities = 38/100 (38%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
Query: 54 YMGYKWQCVEFARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGG--K 111
Y G+++QCVE+ARR+L L G VF + G A EI+++ + V A L N G
Sbjct: 47 YTGFRYQCVEYARRFLLLTTGCVFANCGRASEIYAMDHITHVETGAQYTLHRHHNDGTAT 106
Query: 112 RAPECGALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQN 151
+ P G ++++ E GHV VI+ V ++V IAEQN
Sbjct: 107 QKPAPGDIIVYPYHPELTPWGHVGVISFVDDNRVGIAEQN 146
>gi|146098165|ref|XP_001468343.1| D-alanyl-glycyl endopeptidase-like protein; cysteine peptidase,
Clan CA, family C51 [Leishmania infantum]
gi|134072710|emb|CAM71427.1| D-alanyl-glycyl endopeptidase-like protein; cysteine peptidase,
Clan CA, family C51, putative [Leishmania infantum]
Length = 369
Score = 66.6 bits (161), Expect = 3e-09, Method: Composition-based stats.
Identities = 69/217 (31%), Positives = 105/217 (48%), Gaps = 38/217 (17%)
Query: 4 RSPNITTHDPFGSLLGYAPGGVAIYSS----------DYNTADAQEYPDDAAFRSYLGGE 53
R P +T PF ++LG GV YS+ Y E ++ +Y+ +
Sbjct: 159 REPCVT---PFSTILGVF-NGVFGYSNCNDSYVSTELGYINLTVLELNNETGQVTYISKQ 214
Query: 54 -YMGYKWQCVEFARRYLYLNYGM----VFTDVGMAYEIFSLRFLRQVVNDAL-LPLQAFA 107
Y G WQCVE+ARRY ++ G F V A +I++L F+R + N ++ LPL F
Sbjct: 215 FYTGLAWQCVEYARRY-WMQSGTPQPAYFESVPGAADIWNLTFVRLLSNTSMKLPLHRFR 273
Query: 108 NGGK-----RAPECGALLIW--QEGGEFKHTGHVAVITEV---LADKVRIAEQNVIHSRL 157
NG + P G ++I+ Q+GG F + GHVAVI V + +AEQN ++
Sbjct: 274 NGDPVTSNLQVPAVGDIIIYPVQDGG-FPY-GHVAVIASVEISTHGAIYVAEQNWANAVW 331
Query: 158 PSG-QQWTRELPMTVTAGRYRLQDTFDDT--EILGWM 191
PS ++R +P+ + T DD +I+GWM
Sbjct: 332 PSAYHNYSRRIPLYYEMLTSTI--TLDDPKGKIIGWM 366
>gi|145514600|ref|XP_001443205.1| hypothetical protein [Paramecium tetraurelia]
gi|124410583|emb|CAK75808.1| unnamed protein product [Paramecium tetraurelia]
Length = 265
Score = 64.3 bits (155), Expect = 1e-08, Method: Composition-based stats.
Identities = 56/200 (28%), Positives = 88/200 (44%), Gaps = 18/200 (9%)
Query: 14 FGSLLGYAPGGVAIYSSDYNTADAQEY-----PDDAAFRS--YLGGEYMGYK--WQCVEF 64
FG L+G GV YS +T E P++ F ++G +Y +K +QCV F
Sbjct: 56 FGVLIGKG-NGVPAYSCQNDTQHLHELEHFLQPNETGFNQTVFIGMKYRYFKPRYQCVHF 114
Query: 65 ARRYLYLNYGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQE 124
AR Y +G F + A EIF L + N L F NG + G LLIW +
Sbjct: 115 ARYYWIQKFGSAFPGIDTADEIFDLTYAIDYKNGKYRNLTKFYNGMSTSIRAGDLLIWNK 174
Query: 125 GGEFKHTGHVAVITEVLADK----VRIAEQNVIHSRLPSGQQWTRELPMTVTAGRYRLQD 180
+ GHVAV+ +V + I E+N + + Q+ R+L + + + L
Sbjct: 175 SYPYYPYGHVAVVLDVQLGAEEPYITIGEEN--YDDIWDSNQYARKLKASTS--NFGLVY 230
Query: 181 TFDDTEILGWMIQTDNEEFS 200
++ EI G Q ++++
Sbjct: 231 VINEREITGLSPQEKCKDYN 250
>gi|68129119|emb|CAJ06795.1| D-alanyl-glycyl endopeptidase-like protein; cysteine peptidase,
Clan CA, family C51, putative [Leishmania major]
Length = 232
Score = 64.3 bits (155), Expect = 1e-08, Method: Composition-based stats.
Identities = 65/211 (30%), Positives = 105/211 (49%), Gaps = 26/211 (12%)
Query: 2 PDRSPNITTHDPFGSLLGYAPGGVAIYSSD--YNTADAQEYPDDAAFRSYLGGE-YMGYK 58
P +P T F + GY+ + S++ Y E ++ +Y+ + Y G
Sbjct: 24 PCVTPLGTILGVFNGVFGYSNCNDSYVSTELRYINLTVPELNNETGQLTYISKQFYTGLA 83
Query: 59 WQCVEFARRYLYLNYGM----VFTDVGMAYEIFSLRFLRQVVNDAL-LPLQAFANGGK-- 111
WQCVE+ARRY ++ G F V A ++++L F+R + N ++ LPL+ + NG +
Sbjct: 84 WQCVEYARRY-WMQRGTPQPAYFDSVLGAADVWNLTFVRLLSNASITLPLRRYWNGDRVT 142
Query: 112 ---RAPECGALLIW--QEGGEFKHTGHVAVITEV---LADKVRIAEQNVIHSRLPSGQQ- 162
+ P G ++I+ Q+GG F + GHVAVI V + +AEQN ++ S
Sbjct: 143 DNHQIPAIGDIIIYPVQDGG-FPY-GHVAVIANVELSTHGAIYVAEQNWANAVWSSPHHN 200
Query: 163 WTRELPMTVTAGRYRLQDTFDDTE--ILGWM 191
+TR +PM + T DD+E I+GWM
Sbjct: 201 YTRRIPMFYDMLTSTI--TLDDSEHQIIGWM 229
>gi|84043610|ref|XP_951595.1| D-alanyl-glycyl endopeptidase [Trypanosoma brucei TREU927]
gi|33348478|gb|AAQ15803.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma brucei]
gi|62359166|gb|AAX79610.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma brucei]
Length = 280
Score = 63.9 bits (154), Expect = 2e-08, Method: Composition-based stats.
Identities = 63/205 (30%), Positives = 95/205 (46%), Gaps = 23/205 (11%)
Query: 2 PDRSPNITTH--DPFGSLLGYAPGGVAIYSSDYNTADAQEYPD-DAAFRSYLGGEYMGYK 58
P+ S + H +P G++LG A GV YS+ T + Y + A SY G K
Sbjct: 81 PEGSGKVEKHCLNPVGAILG-AHEGVFSYSNCGATENTTTYNNVTVAGTSYQSG----LK 135
Query: 59 WQCVEFARRYLYLN---YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKRA-- 113
WQCVE+ARRY L F V A +I+ L+ ++ + PL + NG +
Sbjct: 136 WQCVEYARRYWMLRGTPQPATFGSVDGAADIWDLKDVQLLNGQKRKPLLKYHNGNATSAN 195
Query: 114 --PECGALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSG-QQWTRELPMT 170
P G LLI+ GHVAV+ V D++ +AEQN ++ P ++R L ++
Sbjct: 196 SKPRVGDLLIYPRQPNGFPCGHVAVVAGVTGDRMFVAEQNWENAAWPGPYHNYSRVLNLS 255
Query: 171 V----TAGRYRLQDTFDDTEILGWM 191
TA R + D+ + GW+
Sbjct: 256 CNPNGTACTVREK---DNVTVQGWV 277
>gi|71413979|ref|XP_809108.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma cruzi
strain CL Brener]
gi|70873439|gb|EAN87257.1| D-alanyl-glycyl endopeptidase-like protein, putative [Trypanosoma
cruzi]
Length = 195
Score = 62.8 bits (151), Expect = 4e-08, Method: Composition-based stats.
Identities = 60/193 (31%), Positives = 92/193 (47%), Gaps = 25/193 (12%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
P+G++LG A G V YS+ D++ + ++ + G +W C+EFARRY L
Sbjct: 10 PYGAILGVA-GDVFAYSNCIRNYDSKSRNNVSS-----QNKESGLEWDCMEFARRYWMLR 63
Query: 73 YGMV---FTDVGMAYEIFSLRFLRQVVNDALLPLQAFANG-----GKRAPECGALLIWQE 124
V F V A +I++L +R +++ + PL + NG G AP G LLI+
Sbjct: 64 GTPVRATFDSVVGAADIWALNSVR-LLDGSKTPLLKYPNGLPRRDGGSAPRAGDLLIYPR 122
Query: 125 GGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSG-QQWTRELPMTVTAGRYRLQDTFD 183
GHVAV+ V + V +AEQN + P +RE+ M + + D ++
Sbjct: 123 QRNDFPFGHVAVVVGVTKNSVLVAEQNWDNKMWPGPYHNHSREIRMLYSP----IHDAYN 178
Query: 184 DTE-----ILGWM 191
TE I GWM
Sbjct: 179 ITEEENIIIDGWM 191
>gi|83649227|ref|YP_437662.1| Glutathionylspermidine synthase [Hahella chejuensis KCTC 2396]
gi|83637270|gb|ABC33237.1| Glutathionylspermidine synthase [Hahella chejuensis KCTC 2396]
Length = 387
Score = 62.4 bits (150), Expect = 5e-08, Method: Composition-based stats.
Identities = 35/106 (33%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
Query: 243 MKGHIVNHGDQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLW 302
M G + Y F+L E ++ L + E+H M L D+V++D++LL+ F+IP++ W
Sbjct: 26 MHGEVYWDESAYYQFSL-EQIENGLEDPSAEIHQMCLEVVDRVVEDERLLRKFSIPEMFW 84
Query: 303 PRLRLSWQNRRYQTITGRMDFCLDERG-LKVYEYNTDSASCHAEAG 347
+R SW++++ ++ R+DF D R K+YE N D+ + E+G
Sbjct: 85 EAVRASWRDQQ-PSLYSRLDFAYDGRNPAKLYENNADTPTSLYESG 129
>gi|71413981|ref|XP_809109.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma cruzi
strain CL Brener]
gi|70873440|gb|EAN87258.1| D-alanyl-glycyl endopeptidase-like protein, putative [Trypanosoma
cruzi]
Length = 280
Score = 62.4 bits (150), Expect = 5e-08, Method: Composition-based stats.
Identities = 52/150 (34%), Positives = 73/150 (48%), Gaps = 19/150 (12%)
Query: 56 GYKWQCVEFARRYLYLNYGMV---FTDVGMAYEIFSLRFLRQVVNDALLPLQAFANG--- 109
G +WQCVEFARRY L V F V A +I++L +R +++ + PL + NG
Sbjct: 132 GLEWQCVEFARRYWMLRGTPVRATFDSVVGAADIWALNSVR-LLDGSKTPLLKYPNGLPR 190
Query: 110 --GKRAPECGALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSG-QQWTRE 166
G AP G LLI+ GHVAV+ V + V +AEQN + P +RE
Sbjct: 191 RDGGSAPRAGDLLIYPRQRNDFPFGHVAVVVGVTKNSVLVAEQNWDNKMWPGPYHNHSRE 250
Query: 167 LPMTVTAGRYRLQDTFDDTE-----ILGWM 191
+ M + + D ++ TE I GWM
Sbjct: 251 IRMLYSP----IHDAYNITEEENIIIDGWM 276
>gi|71388835|ref|XP_802159.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma cruzi
strain CL Brener]
gi|70856649|gb|EAN80713.1| D-alanyl-glycyl endopeptidase-like protein, putative [Trypanosoma
cruzi]
Length = 243
Score = 60.1 bits (144), Expect = 3e-07, Method: Composition-based stats.
Identities = 56/183 (30%), Positives = 88/183 (48%), Gaps = 20/183 (10%)
Query: 13 PFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLN 72
P+G++LG A G V YS+ D++ + ++ + G +W C+EFARRY L
Sbjct: 69 PYGAILGVA-GDVFAYSNCIRNYDSKSRNNVSS-----QNKESGLEWDCMEFARRYWMLR 122
Query: 73 YGMV---FTDVGMAYEIFSLRFLRQVVNDALLPLQAFANG-----GKRAPECGALLIWQE 124
V F V A +I++L +R +++ + PL + NG G AP G LLI+
Sbjct: 123 GTPVRATFDSVVGAADIWALNSVR-LLDGSKTPLLKYPNGLPRRDGGSAPRAGDLLIYPR 181
Query: 125 GGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSG-QQWTRELPMTVTAGRYRLQDTFD 183
GHVAV+ V + V +AEQN + P +RE+ M + + D ++
Sbjct: 182 QRNDFPFGHVAVVVGVTKNSVLVAEQNWDNKMWPGPYHNHSREIRMLYSP----IHDAYN 237
Query: 184 DTE 186
TE
Sbjct: 238 ITE 240
>gi|87200372|ref|YP_497629.1| glutathionylspermidine synthase [Novosphingobium aromaticivorans
DSM 12444]
gi|87136053|gb|ABD26795.1| glutathionylspermidine synthase [Novosphingobium aromaticivorans
DSM 12444]
Length = 381
Score = 57.4 bits (137), Expect = 2e-06, Method: Composition-based stats.
Identities = 36/103 (34%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 252 DQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSWQN 311
D+ +ALS L AT E+H +YL A D +++DD L+ IP +R +WQ
Sbjct: 33 DESAAYALSMEQVETLETATEEVHRLYLEAGDAIVRDDLLMASCGIPGTYHRAVREAWQR 92
Query: 312 RRYQTITGRMDFCLDERGL-KVYEYNTDSASCHAEAGAILPHW 353
R GR DF D G ++ EYN D+ + EA I +W
Sbjct: 93 RGPALDFGRFDFAWDGTGQPRLLEYNCDTPTSLLEASIIQWYW 135
>gi|153832455|ref|ZP_01985122.1| glutathionylspermidine synthase [Vibrio harveyi HY01]
gi|148871250|gb|EDL70122.1| glutathionylspermidine synthase [Vibrio harveyi HY01]
Length = 388
Score = 57.4 bits (137), Expect = 2e-06, Method: Composition-based stats.
Identities = 35/95 (36%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
Query: 254 YRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSWQNRR 313
Y F+LS+ Q ++ T ELH M L D+V++ ++LL IPK +WP++ SWQ RR
Sbjct: 37 YYQFSLSQIEQ-DIEDPTEELHQMCLEIVDEVVRSERLLTQCAIPKAMWPQVASSWQ-RR 94
Query: 314 YQTITGRMDFCLD-ERGLKVYEYNTDSASCHAEAG 347
++ RMDF + K+ E N D+ + E G
Sbjct: 95 EPSLYSRMDFAYNGSSPAKLLENNADTPTSLFETG 129
>gi|156932414|ref|YP_001436330.1| hypothetical protein ESA_00193 [Enterobacter sakazakii ATCC
BAA-894]
gi|156530668|gb|ABU75494.1| hypothetical protein ESA_00193 [Enterobacter sakazakii ATCC
BAA-894]
Length = 395
Score = 56.6 bits (135), Expect = 3e-06, Method: Composition-based stats.
Identities = 36/113 (31%), Positives = 60/113 (53%), Gaps = 6/113 (5%)
Query: 246 HIVN---HGDQYRYFALSESAQHELIRA-TNELHLMYLHATDKVLKDDKLLQYFNIPKLL 301
HI++ + D+ R + + E I + T ELH M L D+ ++D +LL+ IP+L
Sbjct: 24 HIIDDEIYWDESRAYRFTLRQIEEQIESPTAELHEMCLDVVDRAVRDARLLEQLAIPELY 83
Query: 302 WPRLRLSWQNRRYQTITGRMDFCLDERG-LKVYEYNTDSASCHAEAGAILPHW 353
W + SW++R ++ GRMDF +G +K+ EYN D+ + E+ W
Sbjct: 84 WDAIAQSWKDRD-PSLYGRMDFVWTGQGPVKLLEYNADTPTSLYESAYFQWQW 135
>gi|37528140|ref|NP_931485.1| hypothetical protein plu4309 [Photorhabdus luminescens subsp.
laumondii TTO1]
gi|36787577|emb|CAE16681.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii
TTO1]
Length = 388
Score = 56.2 bits (134), Expect = 3e-06, Method: Composition-based stats.
Identities = 32/97 (32%), Positives = 54/97 (55%), Gaps = 3/97 (3%)
Query: 252 DQYRYFALSESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSWQN 311
D+Y F L + +H + T E+H + L A + V+ D+L+ F IP+ +W +R SW+
Sbjct: 35 DRYYQFTLKQIEEH-IEDPTAEIHRLSLQAVEHVVNSDELMARFQIPEAMWSLVRGSWK- 92
Query: 312 RRYQTITGRMDFCLDERG-LKVYEYNTDSASCHAEAG 347
RR ++ R+DF D + K+ E N+D+ + E G
Sbjct: 93 RRDPSLYSRLDFAYDGKNPAKLLEINSDTPTSVYEHG 129
>gi|120597090|ref|YP_961664.1| CHAP domain containing protein [Shewanella sp. W3-18-1]
gi|120557183|gb|ABM23110.1| CHAP domain containing protein [Shewanella sp. W3-18-1]
Length = 215
Score = 55.8 bits (133), Expect = 5e-06, Method: Composition-based stats.
Identities = 59/211 (27%), Positives = 85/211 (40%), Gaps = 30/211 (14%)
Query: 7 NITTHDPFGSLLGYAPGGVAIYSSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFAR 66
N T G ++ G Y+ NT+D + D G +G K+QCVEF +
Sbjct: 30 NFNTKYQVGDVIDSLNGVEIYYNGGVNTSDGRNLSID--------GYNLGIKYQCVEFVK 81
Query: 67 RYLYLNYGMVFTDV-GMAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEG 125
RY Y + D G A + F N+ LQ + NG + P+ LL++
Sbjct: 82 RYFYQRHQHKMPDTYGHARDFFDNSLADGAWNEKRAMLQ-YVNGSQLTPQADDLLVFAP- 139
Query: 126 GEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSGQQWTRE-LPMTVTAGRYRLQDTFDD 184
F GHVA+I EV +V I +QN P +RE P+T G + + D
Sbjct: 140 WLFNPYGHVAIIAEVHDHQVEIVQQN------PGPFGPSREYFPLTQHDGLWYI----DA 189
Query: 185 TEILGWMIQTDNEEFSLPQPMPAPEKLTIHA 215
+ GW+ L P AP + HA
Sbjct: 190 PRLKGWL--------RLQTPTIAPSLFSNHA 212
>gi|54301720|ref|YP_131713.1| hypothetical protein PBPRB0040 [Photobacterium profundum SS9]
gi|90409806|ref|ZP_01217823.1| hypothetical protein P3TCK_03546 [Photobacterium profundum 3TCK]
gi|46915140|emb|CAG21913.1| conserved hypothetical protein [Photobacterium profundum SS9]
gi|90329159|gb|EAS45416.1| hypothetical protein P3TCK_03546 [Photobacterium profundum 3TCK]
Length = 387
Score = 55.8 bits (133), Expect = 5e-06, Method: Composition-based stats.
Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Query: 252 DQYRYFALS-ESAQHELIRATNELHLMYLHATDKVLKDDKLLQYFNIPKLLWPRLRLSWQ 310
D+ Y+ + E + ++ T E+H M L D V++D+ L+ F IP+ +W + SWQ
Sbjct: 33 DETAYYQFTLEQIERDIEDPTEEIHQMCLDVVDTVVRDEYWLRKFQIPEAMWQNVLDSWQ 92
Query: 311 NRRYQTITGRMDFCLDERG-LKVYEYNTDSASCHAEAG 347
R+ ++ R+DF D G K+YE N D+ + E G
Sbjct: 93 -RKEPSLYSRLDFAYDGTGHAKLYENNADTPTSLFETG 129
>gi|84043608|ref|XP_951594.1| D-alanyl-glycyl endopeptidase [Trypanosoma brucei TREU927]
gi|33348476|gb|AAQ15801.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma brucei]
gi|62359165|gb|AAX79609.1| D-alanyl-glycyl endopeptidase-like protein [Trypanosoma brucei]
Length = 273
Score = 55.5 bits (132), Expect = 6e-06, Method: Composition-based stats.
Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 15/148 (10%)
Query: 56 GYKWQCVEFARRYLYLN---YGMVFTDVGMAYEIFSLRFLRQVVNDALLPLQAFANGGKR 112
G +WQCVE+ARRY L F V A +I+ L+ ++ + PL + NG
Sbjct: 126 GMQWQCVEYARRYWMLRGTPQPATFGSVDGAADIWDLKDVQLLNGQKRKPLLKYHNGNAT 185
Query: 113 A----PECGALLIWQEGGEFKHTGHVAVITEVLADKVRIAEQNVIHSRLPSG-QQWTREL 167
+ P G LLI+ GHVAV+ V D++ +AEQN ++ P ++R L
Sbjct: 186 SANSKPRVGDLLIYPRQPNGFPYGHVAVVAGVTGDRMFVAEQNWENTAWPGPYHNYSRVL 245
Query: 168 PMTV----TAGRYRLQDTFDDTEILGWM 191
++ TA R + D+ + GW+
Sbjct: 246 NLSCNPNGTACTVREK---DNVTVQGWV 270
>gi|150006044|ref|YP_001300788.1| glutathionylspermidine synthase [Bacteroides vulgatus ATCC 8482]
gi|149934468|gb|ABR41166.1| glutathionylspermidine synthase [Bacteroides vulgatus ATCC 8482]
Length = 374
Score = 55.5 bits (132), Expect = 6e-06, Method: Composition-based stats.
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 9/135 (6%)
Query: 250 HGDQYR---YFALSESAQHELIRATNELHLMYLHATDKVLKDDK--LLQYFNIPKLLWPR 304
HGD +R Y+ + L ATNE + +Y A +++D+ + + NIPK + R
Sbjct: 24 HGDYWREEAYYRFTAEETACLEEATNEAYRLYCEAAQFIIEDNPEFMERALNIPKEIGER 83
Query: 305 LRLSWQNRRYQTITGRMDFCLDERGL-KVYEYNTDSASCHAEAGAILPHWAALAGLTLRH 363
+R SW ++ GR DF L + G K+ E+N D+ + EA I W +
Sbjct: 84 IRASWDADEL-SLYGRFDFILAKDGTPKILEFNADTPTSLLEASVI--QWQWKEDVFPEC 140
Query: 364 DPGEGLRNALADTWK 378
D G+ L +WK
Sbjct: 141 DQFNGIHEGLVQSWK 155
>gi|146291512|ref|YP_001181936.1| CHAP domain containing protein [Shewanella putrefaciens CN-32]
gi|145563202|gb|ABP74137.1| CHAP domain containing protein [Shewanella putrefaciens CN-32]
Length = 215
Score = 55.1 bits (131), Expect = 8e-06, Method: Composition-based stats.
Identities = 58/195 (29%), Positives = 82/195 (42%), Gaps = 31/195 (15%)
Query: 24 GVAIY-SSDYNTADAQEYPDDAAFRSYLGGEYMGYKWQCVEFARRYLYLNYGMVFTDV-G 81
GV IY + NT+D + D G +G K+QCVEF +RY Y + D G
Sbjct: 46 GVEIYYNGGVNTSDGRNLSID--------GYNLGIKYQCVEFVKRYFYQRHQHKMPDTYG 97
Query: 82 MAYEIFSLRFLRQVVNDALLPLQAFANGGKRAPECGALLIWQEGGEFKHTGHVAVITEVL 141
A + F N+ LQ + NG + P+ LL++ F GHVA+I EV
Sbjct: 98 HARDFFDNSLADGAWNEKRAMLQ-YVNGSQLTPQADDLLVFAP-WLFNPYGHVAIIAEVH 155
Query: 142 ADKVRIAEQNVIHSRLPSGQQWTRE-LPMTVTAGRYRLQDTFDDTEILGWMIQTDNEEFS 200
+V I +QN P +RE P+T G + + D + GW+
Sbjct: 156 DHQVEIVQQN------PGPFGPSREYFPLTQHDGLWYI----DAPRLKGWL--------R 197
Query: 201 LPQPMPAPEKLTIHA 215
L P AP + HA
Sbjct: 198 LQTPTIAPSLFSNHA 212
Database: nr
Posted date: Sep 17, 2007 11:41 AM
Number of letters in database: 999,999,834
Number of sequences in database: 2,976,859
Database: /nucleus1/users/jsaw/ncbi/db/nr.01
Posted date: Sep 17, 2007 11:48 AM
Number of letters in database: 894,087,890
Number of sequences in database: 2,493,262
Lambda K H
0.321 0.136 0.428
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,644,091,875
Number of Sequences: 5470121
Number of extensions: 72813010
Number of successful extensions: 157881
Number of sequences better than 1.0e-05: 79
Number of HSP's better than 0.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 157686
Number of HSP's gapped (non-prelim): 87
length of query: 402
length of database: 1,894,087,724
effective HSP length: 135
effective length of query: 267
effective length of database: 1,155,621,389
effective search space: 308550910863
effective search space used: 308550910863
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 131 (55.1 bits)