BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= SGO_1241
(277 letters)
Database: nr
5,470,121 sequences; 1,894,087,724 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157074906|gb|ABV09589.1| aminoglycoside adenylyltransfer... 543 e-153
gi|125718048|ref|YP_001035181.1| Aminoglycoside adenylyltra... 497 e-139
gi|32261251|gb|AAO12119.1| aminoglycoside adenylyltransfera... 427 e-118
gi|4959487|gb|AAD34368.1|AF129764_2 ANT-like protein [Strep... 401 e-110
gi|32261249|gb|AAO12122.1| aminoglycoside adenylyltransfera... 399 e-109
gi|32448570|gb|AAO34534.1| aminoglycoside adenylyltransfera... 394 e-108
gi|32261257|gb|AAO63751.1| aminoglycoside adenylyltransfera... 390 e-107
gi|32448607|gb|AAO34537.1| aminoglycoside adenylyltransfera... 345 1e-93
gi|32448612|gb|AAO37750.1| aminoglycoside adenylyltransfera... 338 2e-91
gi|32448609|gb|AAO37749.1| aminoglycoside adenylyltransfera... 329 1e-88
gi|32261253|gb|AAO12120.1| aminoglycoside adenylyltransfera... 329 1e-88
gi|32448554|gb|AAO37748.1| truncated aminoglycoside adenyly... 258 4e-67
gi|29377329|ref|NP_816483.1| aminoglycoside 6-adenylyltrans... 194 5e-48
gi|56965390|ref|YP_177122.1| aminoglycoside 6-adenylyltrans... 181 3e-44
gi|52078682|ref|YP_077473.1| aminoglycoside 6-adenylyltrans... 168 3e-40
gi|16079732|ref|NP_390556.1| aminoglycoside 6-adenylyltrans... 164 4e-39
gi|73663233|ref|YP_302014.1| putative aminoglycoside adenyl... 161 4e-38
gi|89208904|ref|ZP_01187383.1| Streptomycin adenylyltransfe... 160 8e-38
gi|42781114|ref|NP_978361.1| aminoglycoside 6-adenylyltrans... 159 2e-37
gi|56962634|ref|YP_174360.1| aminoglycoside 6-adenylyltrans... 157 5e-37
gi|38049244|gb|AAR10415.1| aminoglycoside 6-adenylyltranser... 157 5e-37
gi|1934642|gb|AAB80893.1| aminoglycoside 6-adenylyltransfer... 156 1e-36
gi|30020098|ref|NP_831729.1| Aminoglycoside 6-adenylyltrans... 155 2e-36
gi|118477417|ref|YP_894568.1| aminoglycoside 6-adenylyltran... 155 3e-36
gi|146387710|pdb|2PBE|A Chain A, Crystal Structure Of An Am... 153 1e-35
gi|75762525|ref|ZP_00742383.1| Aminoglycoside 6-adenylyltra... 150 6e-35
gi|47569996|ref|ZP_00240659.1| aminoglycoside 6-adenylyltra... 148 3e-34
gi|146318611|ref|YP_001198323.1| putative aminoglycoside 6-... 148 4e-34
gi|52143457|ref|YP_083372.1| aminoglycoside 6-adenylyltrans... 147 5e-34
gi|30261991|ref|NP_844368.1| aminoglycoside 6-adenylyltrans... 147 6e-34
gi|49481184|ref|YP_036126.1| aminoglycoside 6-adenylyltrans... 144 4e-33
gi|57118014|gb|AAW34139.1| AadE [Campylobacter jejuni] >gi|... 144 5e-33
gi|32470474|ref|NP_863159.1| streptomycin aminoglycoside 6-... 144 7e-33
gi|153853092|ref|ZP_01994501.1| hypothetical protein DORLON... 143 1e-32
gi|52842365|ref|YP_096164.1| aminoglycoside 6-adenylyltrans... 139 1e-31
gi|110556097|dbj|BAE98116.1| aminoglycoside adenyltransfera... 139 2e-31
gi|50657330|dbj|BAD32731.1| hypothetical protein ORF271 [Le... 138 3e-31
gi|156869363|gb|EDO62735.1| hypothetical protein CLOLEP_005... 137 6e-31
gi|1934640|gb|AAB80892.1| aminoglycoside 6-adenylyltransfer... 137 6e-31
gi|148359681|ref|YP_001250888.1| aminoglycoside 6-adenylylt... 135 2e-30
gi|54294999|ref|YP_127414.1| hypothetical protein lpl2079 [... 135 2e-30
gi|156522760|ref|YP_001429534.1| streptomycin adenylase [La... 135 4e-30
gi|153952904|ref|YP_001393669.1| Predicted adenylyltransfer... 134 5e-30
gi|47524488|gb|AAT34976.1| streptomycin adenyltransferase [... 133 1e-29
gi|57854764|ref|YP_187541.1| aminoglycoside 6-adenylyltrans... 133 1e-29
gi|15612885|ref|NP_241188.1| aminoglycoside 6-adenylyltrans... 132 2e-29
gi|54298033|ref|YP_124402.1| hypothetical protein lpp2090 [... 132 2e-29
gi|51832349|gb|AAU10334.1| streptomycin aminoglycoside 6-ad... 132 3e-29
gi|61104773|gb|AAX38180.1| Str [Enterococcus casseliflavus] 132 3e-29
gi|42761424|ref|NP_976271.1| ORF (str) [Staphylococcus aure... 131 3e-29
gi|106894096|ref|ZP_01361218.1| Streptomycin adenylyltransf... 125 4e-27
gi|89098156|ref|ZP_01171041.1| aminoglycoside 6-adenylyltra... 124 4e-27
gi|150391095|ref|YP_001321144.1| adenylyltransferase [Alkal... 124 8e-27
gi|89894067|ref|YP_517554.1| hypothetical protein DSY1321 [... 123 1e-26
gi|152975576|ref|YP_001375093.1| adenylyltransferase [Bacil... 122 3e-26
gi|225996|prf||1405331A str gene 122 3e-26
gi|106893935|ref|ZP_01361058.1| Streptomycin adenylyltransf... 120 8e-26
gi|32266562|ref|NP_860594.1| hypothetical protein HH1063 [H... 116 2e-24
gi|149181905|ref|ZP_01860393.1| aminoglycoside 6-adenylyltr... 115 4e-24
gi|76787192|ref|YP_330559.1| aminoglycoside 6-adenylyltrans... 107 1e-21
gi|77406703|ref|ZP_00783743.1| streptomycin resistance prot... 105 2e-21
gi|22538164|ref|NP_689015.1| streptomycin resistance protei... 105 2e-21
gi|77408031|ref|ZP_00784780.1| streptomycin resistance prot... 105 4e-21
gi|50880298|emb|CAD35323.1| streptomycin resistance protein... 103 1e-20
gi|77411979|ref|ZP_00788309.1| streptomycin resistance prot... 102 2e-20
gi|121633835|ref|YP_976073.1| truncated streptomycin resist... 101 6e-20
gi|47420254|gb|AAT27400.1| aminoglycoside adenyltransferase... 100 1e-19
gi|285308|pir||S25259 streptomycin resistance protein - Bac... 79 3e-13
gi|57118035|gb|AAW34160.1| adenyltransferase [Campylobacter... 74 1e-11
gi|15072724|emb|CAC47931.1| aminoglycoside 6-adenylyltransf... 69 2e-10
gi|89099969|ref|ZP_01172840.1| aminoglycoside 6-adenylyltra... 65 4e-09
gi|37525410|ref|NP_928754.1| hypothetical protein plu1458 [... 62 3e-08
>gi|157074906|gb|ABV09589.1| aminoglycoside adenylyltransferase [Streptococcus gordonii str.
Challis substr. CH1]
Length = 277
Score = 543 bits (1400), Expect = e-153, Method: Composition-based stats.
Identities = 277/277 (100%), Positives = 277/277 (100%)
Query: 1 MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW
Sbjct: 1 MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
Query: 61 LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL 120
LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL
Sbjct: 61 LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL 120
Query: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL
Sbjct: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
Query: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK 240
KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK
Sbjct: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK 240
Query: 241 EAQAFSLKTGFHYDKETAEKMIEYAKERLETNETFTK 277
EAQAFSLKTGFHYDKETAEKMIEYAKERLETNETFTK
Sbjct: 241 EAQAFSLKTGFHYDKETAEKMIEYAKERLETNETFTK 277
>gi|125718048|ref|YP_001035181.1| Aminoglycoside adenylyltransferase, putative [Streptococcus
sanguinis SK36]
gi|125497965|gb|ABN44631.1| Aminoglycoside adenylyltransferase, putative [Streptococcus
sanguinis SK36]
Length = 272
Score = 497 bits (1279), Expect = e-139, Method: Composition-based stats.
Identities = 247/269 (91%), Positives = 256/269 (95%)
Query: 1 MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
M+TE EMFDVILQTAK LQV AVAMSGSR+NPNA KDEFQDYDVVYIVEDL LVADLAW
Sbjct: 1 MRTEIEMFDVILQTAKVLQVEAVAMSGSRTNPNAPKDEFQDYDVVYIVEDLDGLVADLAW 60
Query: 61 LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL 120
L+RFG+R+IEQHVLLDHRRLYLMLFEDGNRIDLTLCPK HIKEWVDSEADFTVLDDPQ L
Sbjct: 61 LDRFGKRMIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKVHIKEWVDSEADFTVLDDPQVL 120
Query: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHL+YATDHLYGICQQELL
Sbjct: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLIYATDHLYGICQQELL 180
Query: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK 240
KLLAWQVAADKGTVDVGKNYKYLFQYLP EKEKEFTALLDFSDQK +TKSL ATMDFFHK
Sbjct: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPTEKEKEFTALLDFSDQKSLTKSLLATMDFFHK 240
Query: 241 EAQAFSLKTGFHYDKETAEKMIEYAKERL 269
EAQAF+LKTGFHYDK TAEKMIEYA+ RL
Sbjct: 241 EAQAFALKTGFHYDKATAEKMIEYAEARL 269
>gi|32261251|gb|AAO12119.1| aminoglycoside adenylyltransferase [Streptococcus oralis]
Length = 270
Score = 427 bits (1098), Expect = e-118, Method: Composition-based stats.
Identities = 219/269 (81%), Positives = 246/269 (91%), Gaps = 2/269 (0%)
Query: 1 MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
M+TE EM D+ILQTAK L+V AVA+SGSR+N DEFQDYDVVY+V+DL L +DLAW
Sbjct: 1 MRTEPEMLDLILQTAKTLKVEAVALSGSRTNQKVQTDEFQDYDVVYVVDDLDNLTSDLAW 60
Query: 61 LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL 120
L++FG R+IEQH +L +RRLYLMLFEDGNRIDLTLCPKE+IKEWV+SEADFTVL+DP+GL
Sbjct: 61 LDQFGARIIEQHNILGNRRLYLMLFEDGNRIDLTLCPKEYIKEWVESEADFTVLEDPKGL 120
Query: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
F+PY+P P+RYWT PAS TDF+KSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL
Sbjct: 121 FSPYSPNPQRYWTNPASQTDFEKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
Query: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK 240
KLLAWQV ADKGT+DVGKNYKYLFQ+LPAEKEKEFTALL+FSDQKKITKSLFA +FFHK
Sbjct: 181 KLLAWQVTADKGTIDVGKNYKYLFQHLPAEKEKEFTALLNFSDQKKITKSLFA--NFFHK 238
Query: 241 EAQAFSLKTGFHYDKETAEKMIEYAKERL 269
EAQAFS+KTGFHYDK TAEKMIEYA+ RL
Sbjct: 239 EAQAFSIKTGFHYDKATAEKMIEYAEARL 267
>gi|4959487|gb|AAD34368.1|AF129764_2 ANT-like protein [Streptococcus mitis]
gi|32261255|gb|AAO12121.1| aminoglycoside adenylyltransferase [Streptococcus mitis]
Length = 276
Score = 401 bits (1030), Expect = e-110, Method: Composition-based stats.
Identities = 191/269 (71%), Positives = 229/269 (85%)
Query: 1 MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
M+TETEM DV+L+TA+ LQV AVAMSGSR++ A+KDEFQDYDVVY+VE+L L+ DL+W
Sbjct: 5 MRTETEMLDVVLKTAETLQVTAVAMSGSRTDTKASKDEFQDYDVVYVVENLDELITDLSW 64
Query: 61 LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL 120
L++FG+R+IEQ V L RRLYLMLFEDGNRIDLTLCPK+ I+EWVDSEA FTVL+DP+ L
Sbjct: 65 LDQFGKRIIEQEVGLGQRRLYLMLFEDGNRIDLTLCPKQQIQEWVDSEAGFTVLEDPEHL 124
Query: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
F PY+P +RYWT PAS TDF+K+CNEFWWVSAYVVKGI RN L+YATDHLYGICQQELL
Sbjct: 125 FEPYSPNIERYWTNPASQTDFEKACNEFWWVSAYVVKGICRNQLIYATDHLYGICQQELL 184
Query: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK 240
K+LAWQVA+ +G V++GKN KYLF +LP EKEKE + LLDFS KIT+SLF TM FH+
Sbjct: 185 KILAWQVASARGRVEIGKNCKYLFNHLPVEKEKELSNLLDFSSLDKITQSLFDTMQLFHQ 244
Query: 241 EAQAFSLKTGFHYDKETAEKMIEYAKERL 269
EAQ+ + K GF YDKE AE+MI+YA+ERL
Sbjct: 245 EAQSLAQKMGFDYDKEVAEEMIQYAEERL 273
>gi|32261249|gb|AAO12122.1| aminoglycoside adenylyltransferase [Streptococcus mitis]
Length = 276
Score = 399 bits (1024), Expect = e-109, Method: Composition-based stats.
Identities = 190/269 (70%), Positives = 227/269 (84%)
Query: 1 MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
M+TETEM DV+L+TA+ LQV AVAMSGSR++ A+KDEFQDYDVVY+VE+L L+ DL+W
Sbjct: 5 MRTETEMLDVVLKTAETLQVTAVAMSGSRTDTKASKDEFQDYDVVYVVENLDELITDLSW 64
Query: 61 LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL 120
L++FG+R+IEQ V L RRLYLMLFEDGNRIDLTLCPK+ I+EWVDSEA FTVL+DP+ L
Sbjct: 65 LDQFGKRIIEQEVGLGQRRLYLMLFEDGNRIDLTLCPKQQIQEWVDSEAGFTVLEDPEHL 124
Query: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
F PY+P +RYWT PAS TDF+K+CNEFWWVSAYVVKGI RN L+YATDHLYGICQQELL
Sbjct: 125 FEPYSPNIERYWTNPASQTDFEKACNEFWWVSAYVVKGICRNQLIYATDHLYGICQQELL 184
Query: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK 240
K+LAWQVA+ +G V++GKN KYLF +LP EKEKE + LLDFS KIT+SLF TM FH+
Sbjct: 185 KILAWQVASARGRVEIGKNCKYLFNHLPVEKEKELSNLLDFSSLDKITQSLFDTMQLFHR 244
Query: 241 EAQAFSLKTGFHYDKETAEKMIEYAKERL 269
EAQ + K GF YDKE AEKM+ YA+E+L
Sbjct: 245 EAQILAQKMGFAYDKEVAEKMMRYAEEKL 273
>gi|32448570|gb|AAO34534.1| aminoglycoside adenylyltransferase [Streptococcus pneumoniae]
gi|32448572|gb|AAO34535.1| aminoglycoside adenylyltransferase [Streptococcus pneumoniae]
Length = 290
Score = 394 bits (1013), Expect = e-108, Method: Composition-based stats.
Identities = 205/270 (75%), Positives = 233/270 (86%)
Query: 1 MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
M+ ETEM D+ILQTAK LQV AVAMSGSR++ A KDEFQDYDVVY+V+D L +DL W
Sbjct: 5 MRAETEMLDLILQTAKTLQVKAVAMSGSRTDTKAPKDEFQDYDVVYVVDDFDNLTSDLYW 64
Query: 61 LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL 120
L++FG+R+IEQ V LDHRRL LMLFEDGNRI+LTLCPKEHIKEWVDSEA+F VL+D +GL
Sbjct: 65 LDQFGKRIIEQEVALDHRRLNLMLFEDGNRINLTLCPKEHIKEWVDSEAEFIVLEDKKGL 124
Query: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
F Y+P+PKR+W PA+ TDF+K+CNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL
Sbjct: 125 FESYSPSPKRFWIHPATETDFEKTCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 184
Query: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK 240
KLLA QVAADKGTVDVGKNYKYLFQYLP EKEKEF+ LLDFS KIT+SL ATM FH+
Sbjct: 185 KLLALQVAADKGTVDVGKNYKYLFQYLPTEKEKEFSDLLDFSSIDKITQSLLATMQLFHR 244
Query: 241 EAQAFSLKTGFHYDKETAEKMIEYAKERLE 270
EAQ + K GF YDKE AEKMIEYA+ER++
Sbjct: 245 EAQRLAQKLGFDYDKEVAEKMIEYAEERVK 274
>gi|32261257|gb|AAO63751.1| aminoglycoside adenylyltransferase [Streptococcus mitis]
Length = 278
Score = 390 bits (1002), Expect = e-107, Method: Composition-based stats.
Identities = 196/270 (72%), Positives = 234/270 (86%)
Query: 1 MKTETEMFDVILQTAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
M+ ETEM D+ILQTAK LQV AVAMSGSR+NP A KDEFQDYDVVY+V+DL L ++L+W
Sbjct: 6 MRAETEMLDLILQTAKTLQVKAVAMSGSRTNPKAPKDEFQDYDVVYVVDDLANLTSNLSW 65
Query: 61 LERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGL 120
L++FG+R+IEQ V LDHRRLYLMLFEDGNRIDLTLC K HI+EWVDSEA FTVL+DP+ L
Sbjct: 66 LDQFGKRIIEQEVALDHRRLYLMLFEDGNRIDLTLCSKAHIQEWVDSEAGFTVLEDPEHL 125
Query: 121 FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELL 180
F P + +RYWT+PA+ TDF+KSCNEFWWVSAYVVKGI RN L+YATDHLY ICQQELL
Sbjct: 126 FEPCSQNLERYWTSPATETDFEKSCNEFWWVSAYVVKGICRNQLIYATDHLYSICQQELL 185
Query: 181 KLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHK 240
K+L+WQVA++K VD+GKNYKYLF YLPA+KE EF+++LDFS+ KIT+SLFATM FFH+
Sbjct: 186 KVLSWQVASEKVAVDIGKNYKYLFNYLPADKENEFSSILDFSNSNKITQSLFATMKFFHQ 245
Query: 241 EAQAFSLKTGFHYDKETAEKMIEYAKERLE 270
EAQ+ + K GF YD+E AEKMIEYA+ERL+
Sbjct: 246 EAQSLANKMGFDYDREVAEKMIEYAEERLQ 275
>gi|32448607|gb|AAO34537.1| aminoglycoside adenylyltransferase [Streptococcus pneumoniae]
gi|32448614|gb|AAO34536.1| aminoglycoside adenylyltransferase [Streptococcus pneumoniae]
Length = 223
Score = 345 bits (886), Expect = 1e-93, Method: Composition-based stats.
Identities = 164/223 (73%), Positives = 190/223 (85%)
Query: 37 DEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLC 96
DEFQDYDVVYIV+DL L +DL+WL++FG+R+IEQHV LDHRRLYLMLFEDGNRIDLTLC
Sbjct: 1 DEFQDYDVVYIVDDLDNLTSDLSWLDQFGKRLIEQHVQLDHRRLYLMLFEDGNRIDLTLC 60
Query: 97 PKEHIKEWVDSEADFTVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVV 156
PKEHI+EWVDSEA FTVL+D +GLF Y+P+PKR+W PA+ TDF SCNEFWWVS+YVV
Sbjct: 61 PKEHIQEWVDSEAGFTVLEDKKGLFESYSPSPKRFWVHPATETDFKNSCNEFWWVSSYVV 120
Query: 157 KGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFT 216
KGI RN L+YA DHLYGICQQE LK+LAWQVA+D+G VDVGKNYK+LF YLPAE++KEF+
Sbjct: 121 KGICRNQLIYAIDHLYGICQQEFLKILAWQVASDRGKVDVGKNYKHLFNYLPAEQKKEFS 180
Query: 217 ALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHYDKETAE 259
LLDFS KIT+SL TM FH+EAQ + K GF YDKE AE
Sbjct: 181 DLLDFSSIDKITQSLLTTMQLFHREAQRLAQKLGFDYDKEVAE 223
>gi|32448612|gb|AAO37750.1| aminoglycoside adenylyltransferase [Streptococcus pneumoniae]
Length = 223
Score = 338 bits (866), Expect = 2e-91, Method: Composition-based stats.
Identities = 163/223 (73%), Positives = 187/223 (83%)
Query: 37 DEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLC 96
DE QDYDVVYIV+DL L +DL+WL FGER+IEQ V+LDHRRLYLMLFEDGNRIDLTLC
Sbjct: 1 DELQDYDVVYIVDDLDNLTSDLSWLAYFGERIIEQEVVLDHRRLYLMLFEDGNRIDLTLC 60
Query: 97 PKEHIKEWVDSEADFTVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVV 156
PK HI+EWVDSEA FTVL+DP+ LF PY+ +RYWT+PA+ T+F KSCNEFWWVSAYVV
Sbjct: 61 PKNHIQEWVDSEAGFTVLEDPEHLFEPYSQNLERYWTSPATETNFVKSCNEFWWVSAYVV 120
Query: 157 KGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFT 216
KGI R ++YAT HLYGICQQ LLK++AWQV +D+G VD+GKNYKYLF YLPAEKEK+F
Sbjct: 121 KGICRKQVIYATYHLYGICQQALLKVMAWQVVSDRGKVDIGKNYKYLFNYLPAEKEKKFL 180
Query: 217 ALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHYDKETAE 259
LLDFS KIT SLFATM FHKEAQ+ + K GF+YDKE AE
Sbjct: 181 NLLDFSSLDKITHSLFATMQLFHKEAQSLAQKLGFYYDKEVAE 223
>gi|32448609|gb|AAO37749.1| aminoglycoside adenylyltransferase [Streptococcus pneumoniae]
Length = 223
Score = 329 bits (844), Expect = 1e-88, Method: Composition-based stats.
Identities = 158/223 (70%), Positives = 184/223 (82%)
Query: 37 DEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLC 96
DEFQDYDV+Y+V+DL L +DL+WL++FG+ +IEQ V LDHRRLYLMLFEDGNRIDLTLC
Sbjct: 1 DEFQDYDVIYVVDDLDNLTSDLSWLDQFGKCIIEQEVALDHRRLYLMLFEDGNRIDLTLC 60
Query: 97 PKEHIKEWVDSEADFTVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVV 156
PKEHI+EWVDSEA F VL+DP+ LF PY+ +R+W PA+ TDF SCNEFWWVSAYVV
Sbjct: 61 PKEHIQEWVDSEAGFAVLEDPEYLFKPYSQNLERFWIHPATETDFKNSCNEFWWVSAYVV 120
Query: 157 KGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFT 216
KGI R ++YATD+LYGICQQELLK+LAWQ +D+G VD+GKNYKYLF YLPAEKEK+F
Sbjct: 121 KGICRKQVIYATDYLYGICQQELLKVLAWQAVSDRGAVDIGKNYKYLFHYLPAEKEKKFL 180
Query: 217 ALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHYDKETAE 259
LLDFS KIT+SLF TM FHKEAQ + K GF YDKE AE
Sbjct: 181 NLLDFSSLDKITQSLFTTMQLFHKEAQFLAQKIGFDYDKEVAE 223
>gi|32261253|gb|AAO12120.1| aminoglycoside adenylyltransferase [Streptococcus oralis]
Length = 223
Score = 329 bits (844), Expect = 1e-88, Method: Composition-based stats.
Identities = 164/223 (73%), Positives = 196/223 (87%)
Query: 37 DEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLC 96
DEFQDYDVVY+V+DL L +DL+WL++FG+R+IEQH +L +RRLYLMLFEDGNRIDLTLC
Sbjct: 1 DEFQDYDVVYVVDDLDNLTSDLSWLDQFGKRIIEQHNVLGNRRLYLMLFEDGNRIDLTLC 60
Query: 97 PKEHIKEWVDSEADFTVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVV 156
PK+HI+EWVDSEAD+TVL D +GLF Y +P+RYWT PAS TDF+K+CNEFWWVSAYVV
Sbjct: 61 PKDHIQEWVDSEADYTVLKDEKGLFESYTTSPQRYWTNPASQTDFEKACNEFWWVSAYVV 120
Query: 157 KGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKGTVDVGKNYKYLFQYLPAEKEKEFT 216
KGI R +YAT+HLYGICQQELLK+LAW+VAAD+GT+D+GKNYKYLF YLPAEKEKEF+
Sbjct: 121 KGICRKQAIYATNHLYGICQQELLKVLAWRVAADRGTIDIGKNYKYLFNYLPAEKEKEFS 180
Query: 217 ALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHYDKETAE 259
LLDFS KIT+SLFATM+ FH+EAQ+ + K GF+YDKE AE
Sbjct: 181 NLLDFSSSDKITQSLFATMNLFHQEAQSLAQKMGFNYDKEVAE 223
>gi|32448554|gb|AAO37748.1| truncated aminoglycoside adenylyltransferase [Streptococcus
pneumoniae]
Length = 155
Score = 258 bits (658), Expect = 4e-67, Method: Composition-based stats.
Identities = 118/155 (76%), Positives = 135/155 (87%)
Query: 37 DEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVLLDHRRLYLMLFEDGNRIDLTLC 96
DEFQDYDVVYIV+DL L +DL+WL++FG+R+IEQHV LDHRRLYLMLFEDGNRIDLTLC
Sbjct: 1 DEFQDYDVVYIVDDLDNLTSDLSWLDQFGKRLIEQHVQLDHRRLYLMLFEDGNRIDLTLC 60
Query: 97 PKEHIKEWVDSEADFTVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVV 156
PKEHI+EWVDSEA FTVL+D +GLF Y+P+PKR+W PA+ TDF SCNEFWWVSAYVV
Sbjct: 61 PKEHIQEWVDSEAGFTVLEDKKGLFESYSPSPKRFWIHPATETDFKNSCNEFWWVSAYVV 120
Query: 157 KGIHRNHLVYATDHLYGICQQELLKLLAWQVAADK 191
KGI R ++YA DHLYGICQQELL LLAWQVA +
Sbjct: 121 KGICRKQVIYAADHLYGICQQELLNLLAWQVAGSR 155
>gi|29377329|ref|NP_816483.1| aminoglycoside 6-adenylyltransferase [Enterococcus faecalis V583]
gi|29344796|gb|AAO82553.1| aminoglycoside 6-adenylyltransferase [Enterococcus faecalis V583]
Length = 287
Score = 194 bits (493), Expect = 5e-48, Method: Composition-based stats.
Identities = 114/275 (41%), Positives = 149/275 (54%), Gaps = 11/275 (4%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EMF +I+ AK + + AV M GSR+N A KD FQD+D+VYIVE
Sbjct: 1 MRTEEEMFQLIMDVAKQEEHIRAVGMVGSRTNVKAPKDSFQDFDIVYIVEPCAEFFETAT 60
Query: 60 WLERFGERVIEQH--------VLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ +FG+ +I Q R +LMLFEDG RIDLTLCP W + ++
Sbjct: 61 WIAKFGQPLIMQRPKEMTLFPTEPKTRETFLMLFEDGQRIDLTLCPLAEKDNWHEGDSLA 120
Query: 112 TVLDDPQGLFAPY-APTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D P + K Y F+ CNEFWWVS YVVKG+ RN L YA H
Sbjct: 121 IILLDKDENLPPLPVASDKNYTVTVPDQQQFNDCCNEFWWVSTYVVKGLCRNELFYAVTH 180
Query: 171 LYGICQQELLKLLAWQVA-ADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
LY CQQELL+LL+WQ A + + VGK +KYL Y+ + + +LLDFS ++
Sbjct: 181 LYEYCQQELLRLLSWQAAWQEPEPISVGKQFKYLKNYVTPDTMDQLASLLDFSSKEACWN 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEY 264
SL T FF AQ F+ F Y + A+K+ EY
Sbjct: 241 SLIKTQAFFDVVAQDFAKMAQFTYHLQEAKKVTEY 275
>gi|56965390|ref|YP_177122.1| aminoglycoside 6-adenylyltransferase [Bacillus clausii KSM-K16]
gi|56911634|dbj|BAD66161.1| aminoglycoside 6-adenylyltransferase [Bacillus clausii KSM-K16]
Length = 289
Score = 181 bits (460), Expect = 3e-44, Method: Composition-based stats.
Identities = 111/272 (40%), Positives = 150/272 (55%), Gaps = 12/272 (4%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+T EM +++L AK+ + + AV M+GSR+N NA KD FQDYD+VYIV D+ + V+D
Sbjct: 1 MRTYNEMINLLLGVAKSDERIRAVCMNGSRTNRNARKDPFQDYDIVYIVRDVDSFVSDPG 60
Query: 60 WLERFGERVI----EQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W++ FGER+I E+ L+ D YLMLF DGNRIDLTLCP E W +
Sbjct: 61 WIDCFGERIIMQTPEKMTLIPPESDGTFAYLMLFTDGNRIDLTLCPIERRATWNQGDRLS 120
Query: 112 TVLDDPQGLFAPY-APTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
VL D P APT YW + T + CNEFWWVS YV KG+ R YA DH
Sbjct: 121 VVLLDKDEALPPLPAPTDCDYWVQKPNQTLYSDCCNEFWWVSTYVAKGLWRQEFTYAYDH 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L + + LL++L W V D V VGK+ KYL QY+ E+ + F + + + +
Sbjct: 181 L-NVIRAMLLRMLEWTVGIDNEFRVSVGKHGKYLEQYVDEERWQLFLSTFPSPTYEDMWR 239
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKM 261
+L+A F + AQ + F Y AE +
Sbjct: 240 ALWAMAHLFEELAQEVAACFSFDYPHSDAENV 271
>gi|52078682|ref|YP_077473.1| aminoglycoside 6-adenylyltransferase [Bacillus licheniformis ATCC
14580]
gi|52784044|ref|YP_089873.1| AadK [Bacillus licheniformis ATCC 14580]
gi|52001893|gb|AAU21835.1| aminoglycoside 6-adenylyltransferase [Bacillus licheniformis ATCC
14580]
gi|52346546|gb|AAU39180.1| AadK [Bacillus licheniformis DSM 13]
Length = 296
Score = 168 bits (426), Expect = 3e-40, Method: Composition-based stats.
Identities = 107/285 (37%), Positives = 154/285 (54%), Gaps = 21/285 (7%)
Query: 1 MKTETEMFDVILQTAKA-LQVYAVAMSGSRSNPNAT-------KDEFQDYDVVYIVEDLH 52
M+TE E+ D++L+ A+ +V AV M+GSR+NPN KD F+DYD+VY+V D+
Sbjct: 1 MRTEQEIIDLVLKVAREDSRVRAVGMNGSRTNPNVPRTNPNVPKDPFRDYDIVYVVTDMQ 60
Query: 53 ALVADLAWLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCPKEHIKEW 104
+ + + W++ FGER+I Q L +R YLMLF DG+RIDL L P E E+
Sbjct: 61 SFLDEPGWVDVFGERIIMQTPEAMELFPNELGNRFSYLMLFTDGSRIDLILVPLEEKLEY 120
Query: 105 VDSEADFTV--LDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRN 162
E TV LD Q L PT + YW S F CNEFWW S YV KG+ R
Sbjct: 121 -SREDGLTVILLDKDQDLPVIPPPTDREYWVQKPSPQCFADCCNEFWWTSTYVAKGLWRQ 179
Query: 163 HLVYATDHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDF 221
++YA DHL + + LLK+L W+V + G ++ +GKN K+L +Y+ +
Sbjct: 180 EILYALDHL-NLVRAMLLKMLEWKVGFETGFSLSIGKNAKFLDRYVDQNTWERLLETYPP 238
Query: 222 SDQKKITKSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
+D K++ SLF + F + A A + Y AEK+ +Y +
Sbjct: 239 ADYKRVWNSLFKMWELFEETAAAVAEHLNEQYLFAEAEKVRQYLR 283
>gi|16079732|ref|NP_390556.1| aminoglycoside 6-adenylyltransferase [Bacillus subtilis subsp.
subtilis str. 168]
gi|112961|sp|P17585|AADK_BACSU Aminoglycoside 6-adenylyltransferase (AAD(6))
gi|529016|gb|AAA22190.1| aminoglycoside 6-adenylyltransferase
gi|2635124|emb|CAB14620.1| aminoglycoside 6-adenylyltransferase [Bacillus subtilis subsp.
subtilis str. 168]
Length = 284
Score = 164 bits (416), Expect = 4e-39, Method: Composition-based stats.
Identities = 98/266 (36%), Positives = 152/266 (57%), Gaps = 14/266 (5%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM D+ L A ++ V + GSR+N N D FQDYD+ Y V D+ + +
Sbjct: 1 MRSEQEMMDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQ 60
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCP-KEHIKEWVDSEAD 110
WLE FG+R++ Q L + Y++LFEDGN++DLTL P +E + +++
Sbjct: 61 WLEIFGKRIMMQKPEDMELFPPELGNWFSYIILFEDGNKLDLTLIPIREAEDYFANNDGL 120
Query: 111 FTVLDDPQGLFAPYAPTP--KRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYAT 168
VL D F Y TP ++YW +A +FD CNEFW VS YVVKG+ RN +++A
Sbjct: 121 VKVLLDKDS-FINYKVTPNDRQYWIKRPTAREFDDCCNEFWMVSTYVVKGLARNEILFAI 179
Query: 169 DHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKI 227
DHL I + LL+++AW +A+ KG + +GKNYK++ +YL ++ +E + + +++
Sbjct: 180 DHLNEIVRPNLLRMMAWHIASQKGYSFSMGKNYKFMKRYLSNKEWEELMSTYSVNGYQEM 239
Query: 228 TKSLFATMDFFHKEAQAFSLKTGFHY 253
KSLF F K ++A S + Y
Sbjct: 240 WKSLFTCYALFRKYSKAVSEGLAYKY 265
>gi|73663233|ref|YP_302014.1| putative aminoglycoside adenyltransferase [Staphylococcus
saprophyticus subsp. saprophyticus ATCC 15305]
gi|72495748|dbj|BAE19069.1| putative aminoglycoside adenyltransferase [Staphylococcus
saprophyticus subsp. saprophyticus ATCC 15305]
Length = 261
Score = 161 bits (407), Expect = 4e-38, Method: Composition-based stats.
Identities = 103/263 (39%), Positives = 146/263 (55%), Gaps = 20/263 (7%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM ++IL AK + + AV M+GSR N D QD+D+VYIVE+L ++ADL
Sbjct: 1 MRTEKEMLNLILNIAKQDKNIKAVCMNGSRVNVKIQPDIHQDFDIVYIVENLEDIIADLE 60
Query: 60 WLERFGERVIEQH--------VLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ +FG R+I Q L+ R LMLF+D NRIDLTL K + E++ +
Sbjct: 61 WINQFGNRIITQFPEAQDLYPSELEERYPILMLFDDYNRIDLTLLSKNKLSEYLAEDKLI 120
Query: 112 TVLDDPQGLFAP-YAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
VL D L + + YW + FD+ NE++WVS YV+KGI RN L+Y+ DH
Sbjct: 121 KVLLDKDNLLPKNNSVSEASYWISKPYQKLFDECINEYYWVSTYVMKGIWRNELLYSIDH 180
Query: 171 LYGICQQELLKLLAWQVAADKG-----TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQK 225
L IC++ LL +LAW DKG V+ GK++KYL YL + K E T+ +
Sbjct: 181 L-NICRRMLLLMLAW----DKGYKFDFQVNFGKSFKYLPNYLGSNKNSELTSTYPHLNTN 235
Query: 226 KITKSLFATMDFFHKEAQAFSLK 248
+I ++L+ + F A S K
Sbjct: 236 EIKEALYKMTEMFEYAAVMVSKK 258
>gi|89208904|ref|ZP_01187383.1| Streptomycin adenylyltransferase [Bacillus weihenstephanensis
KBAB4]
gi|89153162|gb|EAR73252.1| Streptomycin adenylyltransferase [Bacillus weihenstephanensis
KBAB4]
Length = 292
Score = 160 bits (405), Expect = 8e-38, Method: Composition-based stats.
Identities = 97/277 (35%), Positives = 148/277 (53%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM D+I+ TAK + + AV M+GSR NPN KD FQDYD++Y+V+D+ + + +
Sbjct: 1 MRTEKEMLDLIINTAKEDERIRAVIMNGSRVNPNVKKDCFQDYDIIYVVKDIQSFTCNHS 60
Query: 60 WLERFGERVI----EQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFGE +I E+ LL D + YLM F DGNRIDL L P + I +++ ++
Sbjct: 61 WINRFGEIMIVQMPEEMSLLPADKDGKFPYLMQFMDGNRIDLMLVPVDLINKFIGQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S V KG+ R L YA
Sbjct: 121 KLLLDKDKCIGEFPPASDKDYVIKNPTEKEFLDCCNEFWWCSTNVGKGLWREELSYAKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L G + L+ +L W + TV+ GK K+ QY+ + ++F ++ + I +
Sbjct: 181 LEGPMRDMLIVMLEWHIGMKTNFTVNTGKFGKHFEQYVEKDTWEQFRNTFSNAEYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F D F + A + G+ Y ++ +K+ Y K
Sbjct: 241 SFFVMGDLFREVANEIANTYGYQYPQDDDDKVTSYLK 277
>gi|42781114|ref|NP_978361.1| aminoglycoside 6-adenylyltransferase, putative [Bacillus cereus
ATCC 10987]
gi|42737035|gb|AAS40969.1| aminoglycoside 6-adenylyltransferase, putative [Bacillus cereus
ATCC 10987]
Length = 290
Score = 159 bits (402), Expect = 2e-37, Method: Composition-based stats.
Identities = 96/277 (34%), Positives = 147/277 (53%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM D+I+ TAK + + AV M+GSR NPN +D FQDYD++Y+V+D+ + ++
Sbjct: 1 MRTEKEMLDLIINTAKEDERIRAVIMNGSRVNPNVKRDCFQDYDIIYVVKDIRSFTSNHN 60
Query: 60 WLERFGERVI----EQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFGE +I E+ L+ D + YLM F DGNRIDLTL P + IK++V ++
Sbjct: 61 WIHRFGEIMIVQMPEEMSLVPPDGDGKFPYLMQFMDGNRIDLTLVPVDLIKKFVGQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S V KG+ R L YA
Sbjct: 121 KLLLDKDNCMEEFPPASDKDYLIKKPTEKEFLGCCNEFWWCSTNVAKGLWREELSYAKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L G + + +L W + TV+ GK K+ QY + ++F ++ + I +
Sbjct: 181 LEGPVRDMFIVMLEWHIGMKTDFTVNAGKFGKHFEQYFEGDMWEQFKKTFSNAEYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F D F + A + G+ Y + +++ Y K
Sbjct: 241 SFFVMGDLFREVANEIASAYGYQYPQGDDDRVTSYLK 277
>gi|56962634|ref|YP_174360.1| aminoglycoside 6-adenylyltransferase [Bacillus clausii KSM-K16]
gi|56908872|dbj|BAD63399.1| aminoglycoside 6-adenylyltransferase [Bacillus clausii KSM-K16]
Length = 284
Score = 157 bits (398), Expect = 5e-37, Method: Composition-based stats.
Identities = 98/269 (36%), Positives = 153/269 (56%), Gaps = 20/269 (7%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM + L AK + + V + GSR+N T D+FQDYD+ Y V D+ + +
Sbjct: 1 MRSEQEMMTLFLDFAKNDERIRLVTLEGSRTNKAITPDKFQDYDISYFVTDIDSFKENDQ 60
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
WL+ FG+ ++ Q L + Y++LFEDGN++DLTL P +K++ S++D
Sbjct: 61 WLDPFGKAIMMQKPEDMKLFPPELGNWFSYIILFEDGNKLDLTLIPLNEVKDYF-SQSDG 119
Query: 112 TV---LDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYAT 168
V LD + + + YW + +FD CNEFW VS YVVKG+ R +++A
Sbjct: 120 LVEVLLDKDRLVKNEIVADDRHYWLKKPTEREFDDCCNEFWMVSTYVVKGLARKEILFAI 179
Query: 169 DHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQK-- 225
DHL GI + LL+++AW V +++G T VGKNYK++ +YLP E ++ ALL +K
Sbjct: 180 DHLNGIARPNLLRMMAWYVGSERGYTFSVGKNYKFIDRYLPKE---DWEALLSTYCEKGY 236
Query: 226 -KITKSLFATMDFFHKEAQAFSLKTGFHY 253
+ +SLF + F K ++ S G++Y
Sbjct: 237 AETWQSLFTCYELFRKYSKGLSASLGYNY 265
>gi|38049244|gb|AAR10415.1| aminoglycoside 6-adenylyltranserase [Enterococcus faecium]
Length = 284
Score = 157 bits (398), Expect = 5e-37, Method: Composition-based stats.
Identities = 104/285 (36%), Positives = 147/285 (51%), Gaps = 18/285 (6%)
Query: 1 MKTETEMFDVILQTAKAL-QVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM ++IL AK ++ V + GSR+N N KD FQDYDV + V ++
Sbjct: 1 MRSEQEMMNLILSIAKKDDRIRMVTLEGSRTNKNIPKDLFQDYDVTFFVTEMDTFKTSDE 60
Query: 60 WLERFGERVIEQHVLLDHRRL----------YLMLFEDGNRIDLTLCPK-EHIKEWVDSE 108
WL FG ++ Q + L YLMLFEDGNRIDLTL P E + S+
Sbjct: 61 WLSVFGRQIFIQKP--EDMELFPPEWGNWFSYLMLFEDGNRIDLTLIPLLEKDDYFSKSD 118
Query: 109 ADFTVLDDPQGLFAP-YAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYA 167
VL D + P P+ ++YW S +FD CNEFWWVS YVVKG+ R +++A
Sbjct: 119 GLVKVLLDKDEVTNPNITPSDRKYWVKKPSEREFDDCCNEFWWVSTYVVKGLCRKEILFA 178
Query: 168 TDHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKK 226
DHL I + ELL+++ W+V D + VGKN+K+L +Y+ E K D S +K
Sbjct: 179 IDHLNQIVRYELLRMITWKVGIDTDFKLSVGKNHKFLKRYVSDELWKTLMTTYDLSSYEK 238
Query: 227 ITKSLFATMDFFHKEAQAFSLKTGFHYD--KETAEKMIEYAKERL 269
+ +SL F + ++ + F Y E + IE K L
Sbjct: 239 VWESLSICQKLFREVSKEIAKLLSFEYPAYDENITRYIEECKRNL 283
>gi|1934642|gb|AAB80893.1| aminoglycoside 6-adenylyltransferase [Bacillus subtilis]
Length = 261
Score = 156 bits (395), Expect = 1e-36, Method: Composition-based stats.
Identities = 91/243 (37%), Positives = 140/243 (57%), Gaps = 13/243 (5%)
Query: 23 VAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVL-------- 74
V + GSR+N N D FQDYD+ Y V D+ + + WLE FG+R++ Q
Sbjct: 1 VTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQWLEIFGKRIMMQKPEDMELFPPE 60
Query: 75 LDHRRLYLMLFEDGNRIDLTLCP-KEHIKEWVDSEADFTVLDDPQGLFAPYAPTP--KRY 131
L + Y++LFEDGN++DLTL P +E + +++ VL D F Y TP ++Y
Sbjct: 61 LGNWFSYIILFEDGNKLDLTLIPIREAEDYFANNDGLVKVLLDKDS-FINYKVTPNDRQY 119
Query: 132 WTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADK 191
W +A +FD CNEFW VS YVVKG+ RN +++A DHL I + LL+++AW +A+ K
Sbjct: 120 WIKRPTAREFDDCCNEFWMVSTYVVKGLARNEILFAIDHLNEIVRPNLLRMMAWHIASQK 179
Query: 192 G-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTG 250
G + +GKNYK++ +YL ++ +E + + +++ KSLF F K ++A S
Sbjct: 180 GYSFSMGKNYKFMKRYLSNKEWEELMSTYSVNGYQEMWKSLFTCYALFRKYSKAVSEGLA 239
Query: 251 FHY 253
+ Y
Sbjct: 240 YKY 242
>gi|30020098|ref|NP_831729.1| Aminoglycoside 6-adenylyltransferase [Bacillus cereus ATCC 14579]
gi|29895648|gb|AAP08930.1| Aminoglycoside 6-adenylyltransferase [Bacillus cereus ATCC 14579]
Length = 290
Score = 155 bits (393), Expect = 2e-36, Method: Composition-based stats.
Identities = 96/277 (34%), Positives = 147/277 (53%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM D+I+ TA + ++ AV M+GSR NPN +D FQDYD++Y+V D+ + ++
Sbjct: 1 MRTEKEMLDLIINTAIEDERIRAVIMNGSRVNPNVKRDCFQDYDIMYVVNDIQSFTSNHN 60
Query: 60 WLERFGERVIEQ---HVLL-----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFGE +I Q +LL D + YLM F DGNRIDLTL P E IK++V ++
Sbjct: 61 WIHRFGEIMIVQMPEEMLLVPPDEDGKFPYLMQFMDGNRIDLTLVPVELIKKFVGQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S + KG+ R L YA
Sbjct: 121 KLLLDKDNCLEEFPPASDKDYLIKKPTEKEFLDCCNEFWWCSTNIAKGLWREELSYAKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L G + + +L W + TV+ GK K+ QY+ + ++F ++ + I +
Sbjct: 181 LEGPVRDMFIVMLEWHIGMKTDFTVNTGKFGKHFEQYIEEDMWEQFKRTFSNAEYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F D F + A + + Y ++ +K+ Y K
Sbjct: 241 SFFVMGDLFREVANEIANTYEYQYPQDEDDKVTNYLK 277
>gi|118477417|ref|YP_894568.1| aminoglycoside 6-adenylyltransferase [Bacillus thuringiensis str.
Al Hakam]
gi|118416642|gb|ABK85061.1| aminoglycoside 6-adenylyltransferase [Bacillus thuringiensis str.
Al Hakam]
Length = 290
Score = 155 bits (392), Expect = 3e-36, Method: Composition-based stats.
Identities = 95/277 (34%), Positives = 145/277 (52%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM D+I+ TAK + + AV M+GSR NPN KD FQDYD++Y+VED+ + ++
Sbjct: 1 MRTEKEMLDLIINTAKEDERIRAVIMNGSRVNPNVKKDCFQDYDIIYVVEDIRSFTSNHN 60
Query: 60 WLERFGERVI----EQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFGE +I E+ L+ D + YLM F DGNRIDLTL P E I +V ++
Sbjct: 61 WIRRFGEIMIVQMPEEMSLVPPDGDGKFPYLMQFMDGNRIDLTLIPVELINNFVGQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S V KG+ R L Y
Sbjct: 121 KLLLDKDNCMKEFPPASDKDYLIKKPTEKEFLDCCNEFWWCSTNVAKGLWREELSYVKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L G + L+ +L W + V+ GK K+ +Y+ + ++F ++ + I +
Sbjct: 181 LDGPVRDMLIVMLEWHIGMKTDFIVNAGKFGKHFEKYIEKDMWEQFKRTFSNAEYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F + F + A + G+ Y + +++ Y K
Sbjct: 241 SFFVMGNLFREVANEIANAYGYQYPQGDDDRVTSYLK 277
>gi|146387710|pdb|2PBE|A Chain A, Crystal Structure Of An Aminoglycoside 6-Adenyltransferase
From Bacillus Subtilis
Length = 294
Score = 153 bits (387), Expect = 1e-35, Method: Composition-based stats.
Identities = 96/266 (36%), Positives = 145/266 (54%), Gaps = 14/266 (5%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
+++E E D+ L A ++ V + GSR+N N D FQDYD+ Y V D+ + +
Sbjct: 3 LRSEQEXXDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQ 62
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCP-KEHIKEWVDSEAD 110
WLE FG+R+ Q L + Y++LFEDGN++DLTL P +E + +++
Sbjct: 63 WLEIFGKRIXXQKPEDXELFPPELGNWFSYIILFEDGNKLDLTLIPIREAEDYFANNDGL 122
Query: 111 FTVLDDPQGLFAPYAPTP--KRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYAT 168
VL D F Y TP ++YW +A +FD CNEFW VS YVVKG+ RN +++A
Sbjct: 123 VKVLLDKDS-FINYKVTPNDRQYWIKRPTAREFDDCCNEFWXVSTYVVKGLARNEILFAI 181
Query: 169 DHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKI 227
DHL I + LL+ AW +A+ KG + GKNYK+ +YL ++ +E + + ++
Sbjct: 182 DHLNEIVRPNLLRXXAWHIASQKGYSFSXGKNYKFXKRYLSNKEWEELXSTYSVNGYQEX 241
Query: 228 TKSLFATMDFFHKEAQAFSLKTGFHY 253
KSLF F K ++A S + Y
Sbjct: 242 WKSLFTCYALFRKYSKAVSEGLAYKY 267
>gi|75762525|ref|ZP_00742383.1| Aminoglycoside 6-adenylyltransferase [Bacillus thuringiensis
serovar israelensis ATCC 35646]
gi|74489988|gb|EAO53346.1| Aminoglycoside 6-adenylyltransferase [Bacillus thuringiensis
serovar israelensis ATCC 35646]
Length = 289
Score = 150 bits (380), Expect = 6e-35, Method: Composition-based stats.
Identities = 96/277 (34%), Positives = 147/277 (53%), Gaps = 12/277 (4%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM DVI+ TA + ++ AV M+GSR NPN +D FQDYD++Y+V D+ + ++
Sbjct: 1 MRTEKEMLDVIINTAIEDERIRAVIMNGSRVNPNVKRDCFQDYDIMYVVNDIQSFTSNHN 60
Query: 60 WLERFGERVI----EQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFGE +I E+ L+ D + YLM F DGNRIDLTL P E IK++V ++
Sbjct: 61 WVHRFGEIMIVQMPEEMSLVQPDEDGKFPYLMQFMDGNRIDLTLVPVELIKKFVGQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S + KG+ R L YA
Sbjct: 121 KLLLDKDNCLEEFPPASDKDYLVKKPTEKEFLDCCNEFWWCSTNIAKGLWREELSYAKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L G + + +L W + TV+ GK K+ QY+ + ++F ++ + I +
Sbjct: 181 LEGPVRDMFIVMLEWYIGMKTDFTVNTGKFGKHFEQYIEEDMWEQFKRTFSNAEYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F D F + A + + Y ++ +K+ Y K
Sbjct: 241 SFFVMGDLFREVANEIANTYEYQYPQDD-DKVTNYLK 276
>gi|47569996|ref|ZP_00240659.1| aminoglycoside 6-adenylyltransferase [Bacillus cereus G9241]
gi|47553344|gb|EAL11732.1| aminoglycoside 6-adenylyltransferase [Bacillus cereus G9241]
Length = 290
Score = 148 bits (374), Expect = 3e-34, Method: Composition-based stats.
Identities = 91/277 (32%), Positives = 141/277 (50%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM D+I+ AK + + AV M+GSR NP+ +D FQDYD++Y+V ++ + ++
Sbjct: 1 MRTEKEMLDLIINIAKEDESIRAVIMNGSRVNPHVKRDCFQDYDIMYVVNEIQSFTSNHN 60
Query: 60 WLERFGERVI----EQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFGE +I E+ L+ D + YLM F DGNRIDLTL P + I +V ++
Sbjct: 61 WIHRFGEIMIVQMPEEMSLVPPDGDGKFPYLMQFMDGNRIDLTLVPVDLINNFVGQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S V KG+ R L Y
Sbjct: 121 KLLLDKDNCMEAFPPASDKNYLIKKPTEKEFLDCCNEFWWCSTNVAKGLWREELSYVKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
G + + +L W + TV+ GK K+ QY+ + +F + + I +
Sbjct: 181 FEGPVRDMFIVMLEWHIGMKTDFTVNTGKFGKHFEQYIEKDMWVQFKRTFSNAQYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F D F + A + G+ Y ++ +K+ Y K
Sbjct: 241 SFFVMGDLFREVANEIANTYGYRYPQDDDDKVTNYLK 277
>gi|146318611|ref|YP_001198323.1| putative aminoglycoside 6-adenylyltansferase [Streptococcus suis
05ZYH33]
gi|146320811|ref|YP_001200522.1| putative aminoglycoside 6-adenylyltansferase [Streptococcus suis
98HAH33]
gi|15667879|gb|AAL05549.1|AF408195_5 putative aminoglycoside 6-adenylyltansferase [Enterococcus
faecalis]
gi|145689417|gb|ABP89923.1| putative aminoglycoside 6-adenylyltansferase [Streptococcus suis
05ZYH33]
gi|145691617|gb|ABP92122.1| putative aminoglycoside 6-adenylyltansferase [Streptococcus suis
98HAH33]
Length = 287
Score = 148 bits (373), Expect = 4e-34, Method: Composition-based stats.
Identities = 92/277 (33%), Positives = 149/277 (53%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM D++L A+ + + V + GSR+N N KDEFQDYD+ Y V D+ +++
Sbjct: 1 MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDD 60
Query: 60 WLERFGERVIEQ-----HVLLDHRR--LYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFT 112
WL +FG ++ Q + + YLMLF+D N+IDLTL P E + ++ +
Sbjct: 61 WLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIK 120
Query: 113 VLDDPQ-GLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
VL D + PT Y SA ++D CNEFW V+ YV+KG+ R +++A DHL
Sbjct: 121 VLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPYVIKGLCRKEILFAIDHL 180
Query: 172 YGICQQELLKLLAWQVA-ADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
I + ELL++++W+V + ++ VGKNYKY+ +Y+ + + + I KS
Sbjct: 181 NQILRFELLRMMSWKVGIKTEFSLSVGKNYKYINKYIDEDLWNRLLSTYRMDSYENIWKS 240
Query: 231 LFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAKE 267
LF F + ++ + GF Y E + + Y ++
Sbjct: 241 LFICHQLFREVSKEVAELLGFDY-PEYGKNITRYTED 276
>gi|52143457|ref|YP_083372.1| aminoglycoside 6-adenylyltransferase [Bacillus cereus E33L]
gi|51976926|gb|AAU18476.1| aminoglycoside 6-adenylyltransferase [Bacillus cereus E33L]
Length = 290
Score = 147 bits (372), Expect = 5e-34, Method: Composition-based stats.
Identities = 93/277 (33%), Positives = 144/277 (51%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE E+ D+I+ TAK + + AV M+GSR NPN KD FQDYD++Y+V+D+ + ++
Sbjct: 1 MRTEKEILDLIINTAKEDERIRAVIMNGSRVNPNVKKDCFQDYDIMYVVKDIQSFTSNHN 60
Query: 60 WLERFGERVI----EQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFGE +I E+ L+ D + YLM F DGNRIDLTL P + I+ +V ++
Sbjct: 61 WIRRFGEIMIVQMPEEMSLVPADEDGKFPYLMQFMDGNRIDLTLVPVDLIQTFVGQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S V KG+ R L Y
Sbjct: 121 KLLLDKDNCMDEFPPASDKDYLIKKPTEKEFLDCCNEFWWCSTNVAKGLWREELSYVKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L G + L+ +L W + V+ GK K+ +Y+ + +F + + I +
Sbjct: 181 LDGPVRDMLIVMLEWHIGMKTDFIVNAGKFGKHFEKYIEKDMWVQFKRTFSNEEYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F + F + A S G+ Y + +++ Y K
Sbjct: 241 SFFVMGNLFREVANEISNAYGYPYPQGDDDRVTSYLK 277
>gi|30261991|ref|NP_844368.1| aminoglycoside 6-adenylyltransferase, putative [Bacillus anthracis
str. Ames]
gi|47527257|ref|YP_018606.1| aminoglycoside 6-adenylyltransferase, putative [Bacillus anthracis
str. 'Ames Ancestor']
gi|49184832|ref|YP_028084.1| aminoglycoside 6-adenylyltransferase, putative [Bacillus anthracis
str. Sterne]
gi|65319275|ref|ZP_00392234.1| hypothetical protein Bant_01002574 [Bacillus anthracis str. A2012]
gi|30256617|gb|AAP25854.1| aminoglycoside 6-adenylyltransferase, putative [Bacillus anthracis
str. Ames]
gi|47502405|gb|AAT31081.1| aminoglycoside 6-adenylyltransferase, putative [Bacillus anthracis
str. 'Ames Ancestor']
gi|49178759|gb|AAT54135.1| aminoglycoside 6-adenylyltransferase, putative [Bacillus anthracis
str. Sterne]
Length = 290
Score = 147 bits (372), Expect = 6e-34, Method: Composition-based stats.
Identities = 93/277 (33%), Positives = 143/277 (51%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM D+I+ TAK + + AV M+GSR NPN KD FQD+D++Y V+D+ + ++
Sbjct: 1 MRTEKEMIDLIMNTAKEDERIRAVIMNGSRVNPNVKKDCFQDFDIIYAVKDIRSFTSNHN 60
Query: 60 WLERFGERVI----EQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFGE +I E+ L+ D + YLM F DGNRIDLTL P E I +V ++
Sbjct: 61 WIHRFGEIMIVQMPEEMSLIPADEDGKFPYLMQFMDGNRIDLTLAPVELINNFVRQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S V KG+ R L Y
Sbjct: 121 KLLLDKDNCMEGFPPASDKDYLIKKPTEKEFLDCCNEFWWCSTNVAKGLWREELSYVKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L G + L+ +L W + V+ GK K+ +Y+ + +F ++ + I +
Sbjct: 181 LDGPVRDMLIVMLEWHIGMKTDFIVNAGKFGKHFEKYIEKDMWVQFKRTFSNAEYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F + F + A + G+ Y + +++ Y K
Sbjct: 241 SFFDMGNLFREVANEIANAYGYPYPQGDDDRVTSYLK 277
>gi|49481184|ref|YP_036126.1| aminoglycoside 6-adenylyltransferase [Bacillus thuringiensis
serovar konkukian str. 97-27]
gi|49332740|gb|AAT63386.1| aminoglycoside 6-adenylyltransferase [Bacillus thuringiensis
serovar konkukian str. 97-27]
Length = 290
Score = 144 bits (364), Expect = 4e-33, Method: Composition-based stats.
Identities = 91/277 (32%), Positives = 142/277 (51%), Gaps = 11/277 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM D+I+ TAK + + AV M+GSR NPN KD FQD+D++Y V+D+ + ++
Sbjct: 1 MRTEKEMMDLIINTAKEDERIRAVIMNGSRVNPNVKKDCFQDFDIIYAVKDIRSFTSNHN 60
Query: 60 WLERFGE----RVIEQHVLL----DHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W+ RFG ++ E+ L+ D + YLM F DGNRIDLTL P E I +V ++
Sbjct: 61 WIHRFGAIMMVQMPEEMSLIPADEDGKFPYLMQFMDGNRIDLTLVPVELINNFVRQDSLS 120
Query: 112 TVLDDPQGLFAPYAP-TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
+L D + P + K Y + +F CNEFWW S V KG+ R L Y
Sbjct: 121 KLLLDKDNCMEGFPPASDKDYLIKKPTEKEFLDCCNEFWWCSTNVAKGLWREELSYVKGM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L G + L+ +L W + V+ GK K+ +Y+ + +F ++ + I +
Sbjct: 181 LDGPVRDMLIVMLEWHIGMKTDFIVNAGKFGKHFEKYIEKDMWVQFKRTFSNAEYENIWE 240
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAK 266
S F + F + A + G+ Y + +++ Y K
Sbjct: 241 SFFVMGNLFREVANEIANAYGYPYPQGDDDRVTSYLK 277
>gi|57118014|gb|AAW34139.1| AadE [Campylobacter jejuni]
gi|81176602|gb|ABB59530.1| putative adenyltransferase [Pediococcus acidilactici]
gi|104303745|gb|ABF72141.1| AadE [Arcanobacterium pyogenes]
gi|145308144|gb|ABP57330.1| hypothetical protein bst072 [Bacteroides uniformis]
Length = 288
Score = 144 bits (363), Expect = 5e-33, Method: Composition-based stats.
Identities = 85/263 (32%), Positives = 140/263 (53%), Gaps = 10/263 (3%)
Query: 1 MKTETEMFDVILQTAKA-LQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E E++D++L AK ++ V + GSR+N N D+FQD+D+ + V D+ + +D
Sbjct: 1 MRSEKEVYDIVLNFAKTDKRIRMVTLEGSRTNTNIPPDDFQDFDITFFVTDMDSFTSDDK 60
Query: 60 WLERFGERVIEQHV-------LLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFT 112
WL+ FGER+I Q ++ YLMLF D +IDLTL P E I E+ +
Sbjct: 61 WLDIFGERLILQKPEDMELFPAVEKGFSYLMLFTDDVKIDLTLLPLELIDEYFTWDKLVK 120
Query: 113 VL-DDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
+L D + P PT Y + FD CNEFW + YVVKG+ R +++A DH+
Sbjct: 121 LLLDKDNRIVKPPIPTDIDYHLQKPTQRMFDDCCNEFWNTTTYVVKGLCRKEILFAIDHM 180
Query: 172 YGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
I ++ELL++++W + +G +GKNYK++ QY+P E + + + + +S
Sbjct: 181 NDIVRKELLRMISWLIGIKQGFHFSLGKNYKFMKQYVPEELWERLMSTYNMDSYPHMWES 240
Query: 231 LFATMDFFHKEAQAFSLKTGFHY 253
M F + + + + + Y
Sbjct: 241 FEQCMALFREVSSEVACQLDYQY 263
>gi|32470474|ref|NP_863159.1| streptomycin aminoglycoside 6-adenyltransferase [Enterococcus
faecium]
gi|69244932|ref|ZP_00603122.1| Streptomycin adenylyltransferase [Enterococcus faecium DO]
gi|115534846|ref|YP_783928.1| aminoglycoside 6-adenylyltranserase [Enterococcus faecalis]
gi|11991165|gb|AAG42232.1|AF299292_6 streptomycin adenyltransferase [Staphylococcus intermedius]
gi|14456345|gb|AAK62560.1|AF330699_1 aminoglycoside adenyltransferase [Enterococcus faecium]
gi|21886753|gb|AAM77896.1|AF516335_16 aminoglycoside adenyltransferase [Enterococcus faecium]
gi|12957029|emb|CAC29199.1| aminoglycoside 6-adenylyltranserase [Enterococcus faecalis]
gi|28849335|gb|AAO52842.1| streptomycin aminoglycoside 6-adenyltransferase [Enterococcus
faecium]
gi|68196098|gb|EAN10529.1| Streptomycin adenylyltransferase [Enterococcus faecium DO]
Length = 302
Score = 144 bits (362), Expect = 7e-33, Method: Composition-based stats.
Identities = 84/248 (33%), Positives = 137/248 (55%), Gaps = 10/248 (4%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM D++L A+ + + V + GSR+N N KDEFQDYD+ Y V D+ +++
Sbjct: 1 MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDD 60
Query: 60 WLERFGERVIEQ-----HVLLDHRR--LYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFT 112
WL +FG ++ Q + + YLMLF+D N+IDLTL P E + ++ +
Sbjct: 61 WLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIK 120
Query: 113 VLDDPQ-GLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
VL D + PT Y SA ++D CNEFW V+ YV+KG+ R +++A DH
Sbjct: 121 VLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPYVIKGLCRKEILFAIDHF 180
Query: 172 YGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
I + ELL++++W+V + G + VGKNYK++ +Y+ + ++ + + I ++
Sbjct: 181 NQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLWEKLLSTYRMDSYENIWEA 240
Query: 231 LFATMDFF 238
LF F
Sbjct: 241 LFLCHQLF 248
>gi|153853092|ref|ZP_01994501.1| hypothetical protein DORLON_00486 [Dorea longicatena DSM 13814]
gi|149753878|gb|EDM63809.1| hypothetical protein DORLON_00486 [Dorea longicatena DSM 13814]
Length = 288
Score = 143 bits (360), Expect = 1e-32, Method: Composition-based stats.
Identities = 85/263 (32%), Positives = 139/263 (52%), Gaps = 10/263 (3%)
Query: 1 MKTETEMFDVILQTAKA-LQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E E++D++L AK ++ V + GSR+N N D+FQD+D+ + V D+ + +D
Sbjct: 1 MRSEKEVYDIVLNFAKTDKRIRMVTLEGSRTNTNIPPDDFQDFDITFFVTDMDSFTSDDK 60
Query: 60 WLERFGERVIEQHV-------LLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFT 112
WL+ FGER+I Q ++ YLMLF D +IDLTL P E I E+ +
Sbjct: 61 WLDIFGERLILQKPEDMELFPAVEKGFSYLMLFTDDVKIDLTLLPLELIDEYFTWDKLVK 120
Query: 113 VL-DDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
+L D + P PT Y + FD CNEFW + YVVKG+ R +++A DH+
Sbjct: 121 LLLDKDNRIVKPPIPTDIDYHLQKPTQRMFDDCCNEFWNTTTYVVKGLCRKEILFAIDHM 180
Query: 172 YGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
I ++ELL++++W + +G +GKNYK++ QY P E + + + + +S
Sbjct: 181 NDIVRKELLRMISWLIGIKQGFHFSLGKNYKFMKQYAPEELWERLMSTYNMDSYPHMWES 240
Query: 231 LFATMDFFHKEAQAFSLKTGFHY 253
M F + + + + + Y
Sbjct: 241 FEQCMALFREVSSEVACQLDYQY 263
>gi|52842365|ref|YP_096164.1| aminoglycoside 6-adenylyltransferase [Legionella pneumophila subsp.
pneumophila str. Philadelphia 1]
gi|52629476|gb|AAU28217.1| aminoglycoside 6-adenylyltransferase [Legionella pneumophila subsp.
pneumophila str. Philadelphia 1]
Length = 288
Score = 139 bits (351), Expect = 1e-31, Method: Composition-based stats.
Identities = 91/277 (32%), Positives = 147/277 (53%), Gaps = 12/277 (4%)
Query: 2 KTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
+ E M +I++ A + + V M+GSR++P+A KD FQDYD+VY+V ++ + V D W
Sbjct: 5 RDEQTMLTLIIKIANDDERIKIVIMNGSRASPSAKKDIFQDYDIVYLVTEIESFVHDKNW 64
Query: 61 LERFGERVIEQHV--------LLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFT 112
+ +FGE +I Q + YLM F+D NRIDLTL + + E + ++
Sbjct: 65 INQFGELLIMQTPDEMDGQWPKFKGKYTYLMQFKDWNRIDLTLLHIDQL-ETMPRDSQSL 123
Query: 113 VLDDPQGLFAPYA-PTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
+L D L AP+ PT + Y +P + DF CNEF WVS YV KG+ R L+YA
Sbjct: 124 LLLDKDNLIAPFGEPTDEDYLPSPPTEKDFVNCCNEFLWVSTYVAKGLWRKQLIYAKHVS 183
Query: 172 YGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
I ++EL+K+L W + +G KY+ +L E +EF +D K + S
Sbjct: 184 EQIVKEELIKMLMWYAGIQTNFSQPMGTYGKYIENHLELELRQEFLKTYVDADYKNMWAS 243
Query: 231 LFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAKE 267
LF + F+ A S G+ ++++ + +++Y ++
Sbjct: 244 LFKMCEIFNDLAIKISSYFGYSFNQKEFDNVVDYLQD 280
>gi|110556097|dbj|BAE98116.1| aminoglycoside adenyltransferase [Enterococcus faecalis]
Length = 302
Score = 139 bits (350), Expect = 2e-31, Method: Composition-based stats.
Identities = 83/248 (33%), Positives = 136/248 (54%), Gaps = 10/248 (4%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM D++L A+ + + V + GSR+N N KDEFQDYD+ Y V D+ +++
Sbjct: 1 MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDD 60
Query: 60 WLERFGERVIEQ-----HVLLDHRR--LYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFT 112
WL +FG ++ Q + + YLMLF+D N+IDLTL P E + ++ +
Sbjct: 61 WLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIK 120
Query: 113 VLDDPQ-GLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
VL D + PT Y SA ++D CNEFW V+ YV+KG+ R +++A DH
Sbjct: 121 VLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPYVIKGLCRKEILFAIDHF 180
Query: 172 YGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
I + ELL++++ +V + G + VGKNYK++ +Y+ + ++ + + I ++
Sbjct: 181 NQIVRHELLRMISRKVGIETGFKLSVGKNYKFIERYISEDLWEKLLSTYRMDSYENIWEA 240
Query: 231 LFATMDFF 238
LF F
Sbjct: 241 LFLCHQLF 248
>gi|50657330|dbj|BAD32731.1| hypothetical protein ORF271 [Legionella pneumophila]
Length = 271
Score = 138 bits (348), Expect = 3e-31, Method: Composition-based stats.
Identities = 87/259 (33%), Positives = 139/259 (53%), Gaps = 11/259 (4%)
Query: 19 QVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHV----- 73
++ V M+GSR++P+A KD FQDYD+VY+V ++ + V D W+ +FGE +I Q
Sbjct: 6 RIKIVIMNGSRASPSAKKDIFQDYDIVYLVTEIESFVHDKNWINQFGELLIMQTPDEMDG 65
Query: 74 ---LLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGLFAPYA-PTPK 129
+ YLM F+D NRIDLTL + + E + ++ +L D L AP+ P+ +
Sbjct: 66 QWPKFKGKYTYLMQFKDWNRIDLTLLRMDQL-ETMPRDSQSLLLLDKDNLIAPFGEPSDE 124
Query: 130 RYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAA 189
Y +P + DF CNEF WVS YV KG+ R L+YA I ++EL+K+L W
Sbjct: 125 DYLPSPPTEKDFVNCCNEFLWVSTYVAKGLWRKQLIYAKHISEQIVKEELIKMLMWHAGI 184
Query: 190 DKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFSLK 248
+ +G KY+ +L E +EF +D K + SLF + F+ A S
Sbjct: 185 QTNFSQPMGIYGKYIENHLELELRQEFLKTYVDADYKNMWASLFKMCEIFNDLAIKISSY 244
Query: 249 TGFHYDKETAEKMIEYAKE 267
G+ ++++ + +I+Y ++
Sbjct: 245 FGYSFNQKEFDNVIDYLQD 263
>gi|156869363|gb|EDO62735.1| hypothetical protein CLOLEP_00550 [Clostridium leptum DSM 753]
Length = 281
Score = 137 bits (346), Expect = 6e-31, Method: Composition-based stats.
Identities = 93/271 (34%), Positives = 139/271 (51%), Gaps = 12/271 (4%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+++ EM +IL+ AK + + A + GSR + A D FQDYDVV++V+ + +++
Sbjct: 1 MRSQEEMLAIILKKAKQEEHIRAALLQGSRVSKEAKPDCFQDYDVVFLVDAMEPFLSNPR 60
Query: 60 WLERFGERVIEQ--HVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDP 117
W++ FG R+I Q R YLM F DGNRIDLTL ++ D VL D
Sbjct: 61 WIDCFGRRIIMQIPEPPTRTRMTYLMQFADGNRIDLTLVSRD--ARDTDPRVCGMVLLDK 118
Query: 118 QGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQ 177
LF P + + +FD CNEF WVS YV KG+ R+ ++YA HL +
Sbjct: 119 DELFLTPPPKEDPFLVKKPTRREFDGCCNEFLWVSIYVAKGLWRDQVLYAQAHLNDPVRL 178
Query: 178 ELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLD-FSDQKK--ITKSLFA 233
E++K+L W + + +V GK KYL +YL EK + LL + D K+ I ++LF
Sbjct: 179 EMMKMLDWYIGVNTDFSVTTGKCGKYLREYL---DEKSWVKLLKTYPDGKRENIWEALFT 235
Query: 234 TMDFFHKEAQAFSLKTGFHYDKETAEKMIEY 264
D F +A + Y + ++ EY
Sbjct: 236 MGDIFRTAGRAVGRALKYPYPEGEDRRVKEY 266
>gi|1934640|gb|AAB80892.1| aminoglycoside 6-adenylyltransferase [Bacillus subtilis]
Length = 200
Score = 137 bits (345), Expect = 6e-31, Method: Composition-based stats.
Identities = 79/201 (39%), Positives = 117/201 (58%), Gaps = 13/201 (6%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM D+ L A ++ V + GSR+N N D FQDYD+ Y V D+ + +
Sbjct: 1 MRSEQEMMDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQ 60
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCP-KEHIKEWVDSEAD 110
WLE FG+R++ Q L + Y++LFEDGN++DLTL P +E + +++
Sbjct: 61 WLEIFGKRIMMQKPEDMELFPPELGNWFSYIILFEDGNKLDLTLIPIREAEDYFANNDGL 120
Query: 111 FTVLDDPQGLFAPYAPTP--KRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYAT 168
VL D F Y TP ++YW +A +FD CNEFW VS YVVKG+ RN +++A
Sbjct: 121 VKVLLDKDS-FINYKVTPNDRQYWIKRPTAREFDDCCNEFWMVSTYVVKGLARNEILFAI 179
Query: 169 DHLYGICQQELLKLLAWQVAA 189
DHL I + LL+++AW +A+
Sbjct: 180 DHLNEIVRPNLLRMMAWHIAS 200
>gi|148359681|ref|YP_001250888.1| aminoglycoside 6-adenylyltransferase [Legionella pneumophila str.
Corby]
gi|148281454|gb|ABQ55542.1| aminoglycoside 6-adenylyltransferase [Legionella pneumophila str.
Corby]
Length = 288
Score = 135 bits (341), Expect = 2e-30, Method: Composition-based stats.
Identities = 90/277 (32%), Positives = 147/277 (53%), Gaps = 12/277 (4%)
Query: 2 KTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAW 60
+ E M +I++ A + + V M+GSR++P+A KD FQDYD+VY+V ++ + V D W
Sbjct: 5 RDEKTMLALIIKIANDDERIKIVIMNGSRASPSAKKDIFQDYDIVYLVTEIESFVHDKNW 64
Query: 61 LERFGERVIEQHV--------LLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFT 112
+ +FGE +I Q + YLM F+D NRIDLTL + + E + ++
Sbjct: 65 INQFGELLIMQTPDEVDGQWPKFKDKYTYLMQFKDWNRIDLTLLHIDQL-ETMPRDSQSL 123
Query: 113 VLDDPQGLFAPYA-PTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
+L D L AP+ PT + Y +P + +F CNEF WVS YV KG+ R L+YA
Sbjct: 124 LLLDKDNLIAPFGEPTDEDYLPSPPTEKNFVNCCNEFLWVSTYVAKGLWRKQLIYAKHVS 183
Query: 172 YGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
I ++EL+K+L W + +G KY+ +L E +EF +D K + S
Sbjct: 184 EQIVKEELIKMLMWYAGIQTNFSQPMGTYGKYIENHLELELWQEFLKTYVDADYKHMWAS 243
Query: 231 LFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAKE 267
LF + F+ A S G+ ++++ + +++Y ++
Sbjct: 244 LFKMCEIFNDLAIKISSYFGYSFNQKEFDNVVDYLQD 280
>gi|54294999|ref|YP_127414.1| hypothetical protein lpl2079 [Legionella pneumophila str. Lens]
gi|53754831|emb|CAH16319.1| hypothetical protein [Legionella pneumophila str. Lens]
Length = 260
Score = 135 bits (340), Expect = 2e-30, Method: Composition-based stats.
Identities = 86/253 (33%), Positives = 136/253 (53%), Gaps = 11/253 (4%)
Query: 25 MSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHV--------LLD 76
M+GSR++P+A KD FQDYD+VY+V ++ + V D W+ +FGE +I Q
Sbjct: 1 MNGSRASPSAKKDIFQDYDIVYLVTEIESFVHDKNWINQFGELLIMQTPDEMDGQWPKFK 60
Query: 77 HRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGLFAPYA-PTPKRYWTAP 135
+ YLM F+D NRIDLTL + + E + ++ +L D L AP+ P+ + Y +P
Sbjct: 61 GKYTYLMQFKDWNRIDLTLLRMDQL-ETMPRDSQSLLLLDKDNLIAPFGEPSDEDYLPSP 119
Query: 136 ASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKG-TV 194
+ DF CNEF WVS YV KG+ R L+YA I ++EL+K+L W +
Sbjct: 120 PTEKDFVNCCNEFLWVSTYVAKGLWRKQLIYAKHISEQIVKEELIKMLMWYAGIQTNFSQ 179
Query: 195 DVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHYD 254
+G KY+ +L E +EF +D K + SLF + F+ A S G+ ++
Sbjct: 180 PMGFYGKYIENHLELELRQEFLKTYVDADYKNMWASLFKMCEIFNDLAIKISSYFGYSFN 239
Query: 255 KETAEKMIEYAKE 267
++ + +I+Y ++
Sbjct: 240 QKEFDNVIDYLQD 252
>gi|156522760|ref|YP_001429534.1| streptomycin adenylase [Lactococcus lactis subsp. lactis]
gi|2467230|emb|CAA63519.1| streptomycin adenylase [Lactococcus lactis]
Length = 282
Score = 135 bits (339), Expect = 4e-30, Method: Composition-based stats.
Identities = 85/275 (30%), Positives = 140/275 (50%), Gaps = 14/275 (5%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE E+ +++ + A + V +A+ GSR+N N KD+FQDYD + V D+ + +
Sbjct: 1 MRTEKEILNLVSEFAYQRSNVKIIALEGSRTNENIKKDKFQDYDFAFFVSDIECFTHEES 60
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCPKEHIKEWV-DSEAD 110
WL FGE + Q LD+ Y+M F+DG ++D+TL + + + DS+
Sbjct: 61 WLSLFGELLFIQKPEDMELFPPDLDYGYSYIMYFKDGIKMDITLINLKDLNRYFSDSDGL 120
Query: 111 FTVLDDPQGL-FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATD 169
+L D L P YW + +F CNEFW VS YV KG+ R +++A D
Sbjct: 121 VKILVDKDNLVIQEIVPDDSNYWLKKPTEREFYDCCNEFWSVSTYVAKGVFRREILFALD 180
Query: 170 HLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKIT 228
H I + ELL++++W + ++G +GKNYK++ +YL ++ F A + + +K
Sbjct: 181 HFNNILRPELLRMISWYIGFNRGFDFSLGKNYKFINKYLTDKEFNMFLATFEMNGYRKTY 240
Query: 229 KSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIE 263
+S + F + S ++Y EK IE
Sbjct: 241 QSFKLCCELFKYYSNKVSCLGNYNY--PNYEKNIE 273
>gi|153952904|ref|YP_001393669.1| Predicted adenylyltransferase [Clostridium kluyveri DSM 555]
gi|146345785|gb|EDK32321.1| Predicted adenylyltransferase [Clostridium kluyveri DSM 555]
Length = 287
Score = 134 bits (338), Expect = 5e-30, Method: Composition-based stats.
Identities = 91/281 (32%), Positives = 141/281 (50%), Gaps = 13/281 (4%)
Query: 1 MKTETEMFDVILQTAKA-LQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM D+I+ A +++ A + GSR+NPN KD FQDYD+VY+V + + D A
Sbjct: 1 MRSEKEMMDLIIAVANNDVRIRAAYLEGSRANPNVPKDIFQDYDIVYVVTETRSFREDKA 60
Query: 60 WLERFGERVIEQ------HVLLDHRRLY--LMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W++RFGER+ Q + D Y L+ F DGNR+DL + E++ + E
Sbjct: 61 WIDRFGERLYMQYPEENIYYTSDVENCYGWLIQFTDGNRLDLHVKTLENVLNSL--ELYK 118
Query: 112 TVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
T++D + + + YW F +CNEFWW V KG+ RN + YA D +
Sbjct: 119 TLVDKDNIMPQKQVLSDEEYWVKKPVPNQFYCTCNEFWWCLNNVAKGLWRNEIPYAMDMI 178
Query: 172 YGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
+ L +LL W++ D +V GK+ KY+ +YLP +++ + I +
Sbjct: 179 NFQIRPMLRRLLEWKIGIDNDFSVSAGKSAKYMDKYLPKGIYEQYLESYSKAQINAIWDA 238
Query: 231 LFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAKERLET 271
+F D F K + S K F YD A Y ER+++
Sbjct: 239 VFLMCDLFQKISLEVSEKLNFPYDLTEARNSKSYL-ERVKS 278
>gi|47524488|gb|AAT34976.1| streptomycin adenyltransferase [Staphylococcus intermedius]
Length = 282
Score = 133 bits (334), Expect = 1e-29, Method: Composition-based stats.
Identities = 85/275 (30%), Positives = 139/275 (50%), Gaps = 14/275 (5%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE E+ +++ + A + V +A+ GSR+N N KD+FQDYD + V D+ + +
Sbjct: 1 MRTEKEILNLVSEFAYQRSNVKIIALEGSRTNENIKKDKFQDYDFAFFVSDIECFTHEES 60
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCPKEHIKEWV-DSEAD 110
WL FGE + Q LD+ Y+M F+DG ++D+TL + + + DS+
Sbjct: 61 WLSLFGELLFIQKPEDMELFPPDLDYGYSYIMYFKDGIKMDITLINLKDLNRYFSDSDGL 120
Query: 111 FTVLDDPQGLFA-PYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATD 169
+L D L P YW + +F CNEFW VS YV KG+ R +++A D
Sbjct: 121 VKILVDKDNLVTQEIVPDDSYYWLKKPTEREFYDCCNEFWSVSTYVAKGVFRREILFALD 180
Query: 170 HLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKIT 228
H I + ELL++++W + ++G +GKNYK++ +YL ++ F A + + +K
Sbjct: 181 HFNNILRPELLRMISWYIGFNRGFDFSLGKNYKFINKYLTDKEFNMFLATFEMNGYRKTY 240
Query: 229 KSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIE 263
+S + F + S + Y EK IE
Sbjct: 241 QSFKLCCELFKYYSNKVSCLGNYKY--PNYEKNIE 273
>gi|57854764|ref|YP_187541.1| aminoglycoside 6-adenylyltransferase [Staphylococcus epidermidis
RP62A]
gi|57635997|gb|AAW52786.1| aminoglycoside 6-adenylyltransferase [Staphylococcus epidermidis
RP62A]
Length = 279
Score = 133 bits (334), Expect = 1e-29, Method: Composition-based stats.
Identities = 76/225 (33%), Positives = 123/225 (54%), Gaps = 9/225 (4%)
Query: 23 VAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQ-----HVLLDH 77
+ + GSR+N N KDEFQDYD+ Y V D+ +++ WL +FG ++ Q +
Sbjct: 1 MTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPE 60
Query: 78 RR--LYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQ-GLFAPYAPTPKRYWTA 134
+ YLMLF+D N+IDLTL P E + ++ + VL D + PT Y
Sbjct: 61 EKGFSYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVR 120
Query: 135 PASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKG-T 193
SA ++D CNEFW V+ YV+KG+ R +++A DH I + ELL++++W+V + G
Sbjct: 121 KPSAREYDDCCNEFWNVTPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFK 180
Query: 194 VDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFF 238
+ VGKNYK++ +Y+ + ++ + + I ++LF F
Sbjct: 181 LSVGKNYKFIERYISEDLWEKLLSTYRMDSYENIWEALFLCHQLF 225
>gi|15612885|ref|NP_241188.1| aminoglycoside 6-adenylyltransferase [Bacillus halodurans C-125]
gi|10172935|dbj|BAB04041.1| aminoglycoside 6-adenylyltransferase [Bacillus halodurans C-125]
Length = 292
Score = 132 bits (333), Expect = 2e-29, Method: Composition-based stats.
Identities = 94/278 (33%), Positives = 137/278 (49%), Gaps = 14/278 (5%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM DVIL AK + + AV M+GSR+N N KD FQDYD+VY+V D+ + +
Sbjct: 1 MRTEQEMMDVILTIAKKEERIRAVYMNGSRTNSNVPKDLFQDYDIVYVVTDIAPFIQEQQ 60
Query: 60 WLERFGERVIEQH---------VLLDHRRLY--LMLFEDGNRIDLTLCPKEHIKEWVDSE 108
WL++FGE ++ Q V D R Y LMLF DGNRIDLTL KE ++E +++
Sbjct: 61 WLKKFGEPLMIQEPDQLDAGIGVNRDFSRRYAFLMLFTDGNRIDLTLQTKETMREVYEND 120
Query: 109 A-DFTVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYA 167
+LD L P+ Y + +F N FWW V KGI R+ L YA
Sbjct: 121 TLTVPLLDKDHCLPPIPPPSDSDYHVKEPTEGEFISCTNNFWWCLQNVAKGIWRDELPYA 180
Query: 168 TDHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKK 226
+ L +++ W + + + GK KY ++LP + A SD ++
Sbjct: 181 KQMFELTTRASLDEMVNWWIGLENDFQLSTGKLGKYFKKHLPPPYWAMYEATYANSDYEQ 240
Query: 227 ITKSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEY 264
+ +S+F D F A+ + F Y + M +Y
Sbjct: 241 MWESIFIACDLFRTLAKDVAAACSFTYPETDDRNMTDY 278
>gi|54298033|ref|YP_124402.1| hypothetical protein lpp2090 [Legionella pneumophila str. Paris]
gi|53751818|emb|CAH13242.1| hypothetical protein [Legionella pneumophila str. Paris]
Length = 260
Score = 132 bits (332), Expect = 2e-29, Method: Composition-based stats.
Identities = 84/253 (33%), Positives = 135/253 (53%), Gaps = 11/253 (4%)
Query: 25 MSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHV--------LLD 76
M+GSR++P+A KD FQDYD+VY+V ++ + V D W+ +FGE +I Q
Sbjct: 1 MNGSRASPSAKKDIFQDYDIVYLVTEIESFVHDKNWINQFGELLIMQTPDEMDGQWPKFK 60
Query: 77 HRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQGLFAPYA-PTPKRYWTAP 135
+ YLM F+D NRIDLTL + + E + ++ +L D L AP+ P+ + Y +P
Sbjct: 61 GKYTYLMQFKDWNRIDLTLLHIDQL-ETMPRDSQSLLLLDKDNLIAPFGEPSDEDYLPSP 119
Query: 136 ASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKG-TV 194
+ DF CNEF WVS YV KG+ R L+Y I ++EL+K+L W +
Sbjct: 120 PTEKDFVNCCNEFLWVSTYVAKGLWRKQLIYTKHVSEQIVKEELIKMLMWYAGIQTNFSQ 179
Query: 195 DVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHYD 254
+G KY+ +L E +EF +D K + SLF + F+ A S G+ ++
Sbjct: 180 PMGTYGKYIENHLELELWQEFLKTYVDADYKNMWASLFKMCEIFNDLAIKISSYFGYSFN 239
Query: 255 KETAEKMIEYAKE 267
++ + +++Y ++
Sbjct: 240 QKEFDNVVDYLQD 252
>gi|51832349|gb|AAU10334.1| streptomycin aminoglycoside 6-adenyltransferase [Streptococcus
oralis]
Length = 276
Score = 132 bits (331), Expect = 3e-29, Method: Composition-based stats.
Identities = 76/221 (34%), Positives = 121/221 (54%), Gaps = 9/221 (4%)
Query: 27 GSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQ-----HVLLDHRR-- 79
GSR+N N KDEFQDYD+ Y V D+ +++ WL +FG ++ Q + +
Sbjct: 2 GSRANINIPKDEFQDYDITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGF 61
Query: 80 LYLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQ-GLFAPYAPTPKRYWTAPASA 138
YLMLF+D N+IDLTL P E + ++ + VL D + PT Y SA
Sbjct: 62 SYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSA 121
Query: 139 TDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKG-TVDVG 197
++D CNEFW V+ YV+KG+ R +++A DH I + ELL++++W+V + G + VG
Sbjct: 122 REYDDCCNEFWNVTPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVG 181
Query: 198 KNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFF 238
KNYK++ +Y+ + ++ + + I ++LF F
Sbjct: 182 KNYKFIERYISEDLWEKLLSTYRMDSYENIWEALFLCHQLF 222
>gi|61104773|gb|AAX38180.1| Str [Enterococcus casseliflavus]
Length = 245
Score = 132 bits (331), Expect = 3e-29, Method: Composition-based stats.
Identities = 78/243 (32%), Positives = 129/243 (53%), Gaps = 12/243 (4%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE E+ +++ + A + V +A+ GSR+N N KD+FQDYD + V D+ + +
Sbjct: 1 MRTEKEILNLVSEFAYQRSNVKIIALEGSRTNENIKKDKFQDYDFAFFVSDIECFTHEES 60
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCPKEHIKEWV-DSEAD 110
WL FGE + Q LD+ Y+M F+DG ++D+TL + + + DS+
Sbjct: 61 WLSLFGELLFIQKPEDMELFPPDLDYGYSYIMYFKDGIKMDITLINLKDLNRYFSDSDGL 120
Query: 111 FTVLDDPQGL-FAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATD 169
+L D L P YW + +F CNEFW VS YV KG+ R +++A D
Sbjct: 121 VKILVDKDNLVIQEIVPDDSNYWLKKPTEREFYDCCNEFWSVSTYVAKGVFRREILFALD 180
Query: 170 HLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKIT 228
H I + ELL++++W + ++G +GKNYK++ +YL ++ F A + + +K
Sbjct: 181 HFNNILRPELLRMISWYIGFNRGFDFSLGKNYKFINKYLTDKEFNMFLATFEMNGYRKTY 240
Query: 229 KSL 231
+S
Sbjct: 241 QSF 243
>gi|42761424|ref|NP_976271.1| ORF (str) [Staphylococcus aureus]
gi|135002|sp|P12055|STR_STAAU Streptomycin resistance protein
gi|46644|emb|CAA29839.1| ORF (str) [Staphylococcus aureus]
Length = 282
Score = 131 bits (330), Expect = 3e-29, Method: Composition-based stats.
Identities = 84/275 (30%), Positives = 139/275 (50%), Gaps = 14/275 (5%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE E+ +++ + A + V +A+ GSR+N N KD+FQDYD + V D+ + +
Sbjct: 1 MRTEKEILNLVSEFAYQRSNVKIIALEGSRTNENIKKDKFQDYDFAFFVSDIEYFTHEES 60
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCPKEHIKEWV-DSEAD 110
WL FGE + Q LD+ Y+M F+DG ++D+TL + + + DS+
Sbjct: 61 WLSLFGELLFIQKPEDMELFPPDLDYGYSYIMYFKDGIKMDITLINLKDLNRYFSDSDGL 120
Query: 111 FTVLDDPQGLFA-PYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATD 169
+L D L P YW + +F CNEFW VS YV KG+ R +++A D
Sbjct: 121 VKILVDKDNLVTQEIVPDDSNYWLKKPTEREFYDCCNEFWSVSTYVAKGVFRREILFALD 180
Query: 170 HLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKIT 228
H I + ELL++++W + ++G +GKNYK++ +YL ++ A + + +K
Sbjct: 181 HFNNILRPELLRMISWYIGFNRGFDFSLGKNYKFINKYLTDKEFNMLLATFEMNGYRKTY 240
Query: 229 KSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIE 263
+S + F + S ++Y EK IE
Sbjct: 241 QSFKLCCELFKYYSNKVSCLGNYNY--PNYEKNIE 273
>gi|106894096|ref|ZP_01361218.1| Streptomycin adenylyltransferase [Clostridium sp. OhILAs]
gi|106774581|gb|EAT31143.1| Streptomycin adenylyltransferase [Clostridium sp. OhILAs]
Length = 283
Score = 125 bits (313), Expect = 4e-27, Method: Composition-based stats.
Identities = 83/265 (31%), Positives = 146/265 (55%), Gaps = 10/265 (3%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE E+ +++L AK + + + + GSR+N N KDEFQDYD+ Y V D+ + +++
Sbjct: 1 MRTEQEIMNLMLDIAKQDERIRIMILEGSRTNVNIPKDEFQDYDMTYFVIDIKSFISNDE 60
Query: 60 WLERFGERVI----EQHVLLDHRRL---YLMLFEDGNRIDLTLCPKEHIKEWVDSEADFT 112
WL++FG ++ E L Y+M F+D N+IDLTL P E ++++++ +
Sbjct: 61 WLKKFGNIIMMQKPEDMALFPAEESGYSYIMYFDDYNKIDLTLLPLEELEDYLNGDKLMK 120
Query: 113 VLDDPQGLFAPYA-PTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHL 171
V+ D + PT Y SA ++D CNEFW + YVVKG+ R +++A DHL
Sbjct: 121 VILDKDARIQRHIIPTDIDYHINKPSAREYDDCCNEFWNTTPYVVKGLCRKEILFAIDHL 180
Query: 172 YGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKS 230
I + ELL++++W+V + G + VGKN+K++ +Y+ + F + +K+ ++
Sbjct: 181 NQIVRHELLRMISWKVGIETGFKLSVGKNFKFIDRYICQDLWDRFLSTYQMDSYEKVWEA 240
Query: 231 LFATMDFFHKEAQAFSLKTGFHYDK 255
L F + + + + + Y K
Sbjct: 241 LLLCHQLFREVSGEVAKQLHYTYPK 265
>gi|89098156|ref|ZP_01171041.1| aminoglycoside 6-adenylyltransferase [Bacillus sp. NRRL B-14911]
gi|89087013|gb|EAR66129.1| aminoglycoside 6-adenylyltransferase [Bacillus sp. NRRL B-14911]
Length = 280
Score = 124 bits (312), Expect = 4e-27, Method: Composition-based stats.
Identities = 80/240 (33%), Positives = 120/240 (50%), Gaps = 11/240 (4%)
Query: 25 MSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVL--------LD 76
+ GS +N N KDEFQDYD Y V D+ WL FGER+I Q L
Sbjct: 20 LEGSLTNTNIPKDEFQDYDFSYFVTDMDYFKKSDDWLSSFGERIIMQKPEAMELYPPELG 79
Query: 77 HRRLYLMLFEDGNRIDLTLCPKEHIKEWV-DSEADFTVLDDPQGLFA-PYAPTPKRYWTA 134
+ YLM+FEDG +IDLTL P +++ +S+ VL D L PT Y
Sbjct: 80 NWYSYLMIFEDGTKIDLTLIPLNEYEDYFKNSDGLVEVLLDKDNLIQNSVIPTDSMYHIQ 139
Query: 135 PASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKG-T 193
S FD CNEFW S YVVKG+ R +++A D + + L +L W+V + G +
Sbjct: 140 KPSEQSFDDCCNEFWMTSTYVVKGLARREILFAIDIMNNAFRPSLHTMLRWKVGMETGFS 199
Query: 194 VDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHY 253
+ +GK+ K+L +Y+ + + + D KK+ ++L +++ F + + + GF Y
Sbjct: 200 LSIGKSDKFLKEYISEDMWNKVLSTYDMGSYKKMWEALNTSIELFRETSHFIAETFGFKY 259
>gi|150391095|ref|YP_001321144.1| adenylyltransferase [Alkaliphilus metalliredigens QYMF]
gi|149950957|gb|ABR49485.1| adenylyltransferase [Alkaliphilus metalliredigens QYMF]
Length = 296
Score = 124 bits (310), Expect = 8e-27, Method: Composition-based stats.
Identities = 90/275 (32%), Positives = 136/275 (49%), Gaps = 12/275 (4%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE EM D IL TAK + + AV M+GSR ++KD FQDYD+VY V D + +
Sbjct: 1 MRTEKEMMDRILNTAKEDERIRAVVMNGSRVGNPSSKDCFQDYDIVYFVNDFEYFACNHS 60
Query: 60 WLERFGERVI------EQHVLLDH--RRLYLMLFEDGNRIDLTLCPKEHIKEWVDSEADF 111
W++ FGER++ + + + D+ R Y +LF+DGNRIDLT E+I ++++
Sbjct: 61 WIDIFGERIMLEMPSYKDYEVSDYNGRFNYQILFKDGNRIDLTFASIENIDTVIENDRVG 120
Query: 112 TVLDDPQGLFAPYAPTP-KRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDH 170
L D GL + + Y+ + + F+ SCN FWW+ V KGI R L YA
Sbjct: 121 ITLLDKDGLLQSIVFSGVEVYFVSKPTKRAFENSCNSFWWILQNVAKGIKRRELPYAIKM 180
Query: 171 LYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITK 229
L I + +L + +W + V GK KYL +YL + + + I K
Sbjct: 181 L-NIARNDLDTVASWYIGMKHDFKVLTGKMGKYLERYLDENLWNLYKDTFPTGNYEDIWK 239
Query: 230 SLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEY 264
SLF + A + + + Y + + M EY
Sbjct: 240 SLFCACKLYRLLATEIADQFSYCYPYDDDKLMSEY 274
>gi|89894067|ref|YP_517554.1| hypothetical protein DSY1321 [Desulfitobacterium hafniense Y51]
gi|109646341|ref|ZP_01370245.1| adenylyltransferase [Desulfitobacterium hafniense DCB-2]
gi|89333515|dbj|BAE83110.1| hypothetical protein [Desulfitobacterium hafniense Y51]
gi|109641587|gb|EAT51141.1| adenylyltransferase [Desulfitobacterium hafniense DCB-2]
Length = 289
Score = 123 bits (309), Expect = 1e-26, Method: Composition-based stats.
Identities = 87/289 (30%), Positives = 143/289 (49%), Gaps = 19/289 (6%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EM ++IL TAK + + AV M+GSR+NPN KD +QDYD+V++V + + +AD
Sbjct: 1 MRSEKEMMEIILSTAKKDERIRAVYMNGSRTNPNVPKDIYQDYDIVFVVTETDSFLADKD 60
Query: 60 WLERFGERVI------------EQHVLLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDS 107
W+ FG+ +I EQH R +L+L EDGNR+DL + KE ++
Sbjct: 61 WIGGFGKPLIVQEPDLNDNAWGEQHD-FSRRYAWLILLEDGNRLDLVIEIKEEAQKNFIG 119
Query: 108 EADFTVLDDPQGLFAPYAPTP--KRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLV 165
+ +L D G F P P P + Y + + CN F W V KGI R+ L
Sbjct: 120 DKLTILLLDKDG-FLPEIPRPTDEDYHLKKPNEAQYRACCNNFLWCLNNVAKGIARDELP 178
Query: 166 YATDHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQ 224
YA + + + +L +++W + + G +V VGK K+ ++L E + S
Sbjct: 179 YAMEMYNCVVRNDLKDMISWYIGINTGFSVSVGKMGKHFKKFLTQELYTMYAQTYSDSSY 238
Query: 225 KKITKSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAKERLETNE 273
+ ++F + F A + G+ Y+ + + M Y R++ N+
Sbjct: 239 ENFWAAIFIACELFRSIAPEVADYFGYTYNWQDDKNMATYLN-RVKNND 286
>gi|152975576|ref|YP_001375093.1| adenylyltransferase [Bacillus cereus subsp. cytotoxis NVH 391-98]
gi|152024328|gb|ABS22098.1| adenylyltransferase [Bacillus cereus subsp. cytotoxis NVH 391-98]
Length = 293
Score = 122 bits (305), Expect = 3e-26, Method: Composition-based stats.
Identities = 86/281 (30%), Positives = 130/281 (46%), Gaps = 14/281 (4%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M++E EMFD+I+ A + ++ AV M+GSR+N N KD FQDYD+VY+V D + + D
Sbjct: 1 MRSEKEMFDLIIGFAQRDERIRAVYMNGSRTNSNIPKDIFQDYDIVYVVTDTASFIEDQR 60
Query: 60 WLERFGERVIEQH-----------VLLDHRRLYLMLFEDGNRIDLTLCPKE-HIKEWVDS 107
W+ FGE ++ Q + + YLMLF DGNRIDL + K +K++
Sbjct: 61 WITMFGELLMMQEPDKNDQLKNPTIDFKNSYGYLMLFTDGNRIDLHIETKSAMLKDYGKD 120
Query: 108 EADFTVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYA 167
+ +LD L PT Y A+ + CN+FWW V KGI R+ L YA
Sbjct: 121 KLTVPLLDKDNILPTIPTPTDVDYHVKKATELMYISCCNDFWWCLQNVAKGIWRDELPYA 180
Query: 168 TDHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKK 226
+ + L ++++W + + GK KY +YLP K + +
Sbjct: 181 KQMFECVIRARLDEMVSWWIGMKYDFQISTGKMGKYFKEYLPKSYWKMYEETYSDYRYEN 240
Query: 227 ITKSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAKE 267
S+F + F A + F Y + M Y K+
Sbjct: 241 FWHSIFVACELFRILATNVADVLSFTYPTRDDQNMTTYLKQ 281
>gi|225996|prf||1405331A str gene
Length = 257
Score = 122 bits (305), Expect = 3e-26, Method: Composition-based stats.
Identities = 77/250 (30%), Positives = 123/250 (49%), Gaps = 13/250 (5%)
Query: 25 MSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVL--------LD 76
+ GSR+N N KD+FQDYD + V D+ + +WL FGE + Q LD
Sbjct: 1 LEGSRTNENIKKDKFQDYDFAFFVSDIEYFTHEESWLSLFGELLFIQKPEDMELFPPDLD 60
Query: 77 HRRLYLMLFEDGNRIDLTLCPKEHIKEWV-DSEADFTVLDDPQGLFA-PYAPTPKRYWTA 134
Y+M F+DG ++D+TL + + + DS+ +L D L P YW
Sbjct: 61 TGYSYIMYFKDGIKMDITLINLKDLNRYFSDSDGLVKILVDKDNLVTQEIVPDDSNYWLK 120
Query: 135 PASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKG-T 193
+ +F CNEFW VS YV KG+ R +++A DH I + ELL++++W + ++G
Sbjct: 121 KPTEREFYDCCNEFWSVSTYVAKGVFRREILFALDHFNNILRPELLRMISWYIGFNRGFD 180
Query: 194 VDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHY 253
+GKNYK++ +YL ++ A + + +K +S + F + S ++Y
Sbjct: 181 FSLGKNYKFINKYLTDKEFNMLLATFEMNGYRKTYQSFKLCCELFKYYSNKVSCLGNYNY 240
Query: 254 DKETAEKMIE 263
EK IE
Sbjct: 241 --PNYEKNIE 248
>gi|106893935|ref|ZP_01361058.1| Streptomycin adenylyltransferase [Clostridium sp. OhILAs]
gi|106774736|gb|EAT31297.1| Streptomycin adenylyltransferase [Clostridium sp. OhILAs]
Length = 269
Score = 120 bits (301), Expect = 8e-26, Method: Composition-based stats.
Identities = 81/255 (31%), Positives = 121/255 (47%), Gaps = 13/255 (5%)
Query: 25 MSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQH-----------V 73
M+GSR+NPN KD FQDYD+VY+V + + + D W+ FGE ++ Q V
Sbjct: 1 MNGSRTNPNVPKDIFQDYDIVYVVTETESFIEDRQWINIFGEFIMVQEPDRLDKAIGMKV 60
Query: 74 LLDHRRLYLMLFEDGNRIDLTLCPKEH-IKEWVDSEADFTVLDDPQGLFAPYAPTPKRYW 132
YLMLF DGNRIDL + KE+ +K ++ + +LD L PT + Y+
Sbjct: 61 DFSQSYAYLMLFVDGNRIDLQIETKEYMMKNYLKDKLTVPLLDKDHCLPDIPLPTERGYY 120
Query: 133 TAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVA-ADK 191
+ F N+FWW V KGI R+ L Y+ I + L +++W + A
Sbjct: 121 IKRPTEGHFISCTNDFWWCLQNVAKGIWRDQLPYSKYMFECIVRTNLEYMISWWIGIAYD 180
Query: 192 GTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGF 251
V +G KY +YLP E K + S+ I +++F F + + F
Sbjct: 181 FQVSLGAMNKYFKKYLPKEYWKMYEKTYADSNYDHIWEAIFVACQLFRILGRDVATAFDF 240
Query: 252 HYDKETAEKMIEYAK 266
Y +E KMI+Y +
Sbjct: 241 SYPEEDDLKMIKYLR 255
>gi|32266562|ref|NP_860594.1| hypothetical protein HH1063 [Helicobacter hepaticus ATCC 51449]
gi|32262613|gb|AAP77660.1| conserved hypothetical protein [Helicobacter hepaticus ATCC 51449]
Length = 293
Score = 116 bits (290), Expect = 2e-24, Method: Composition-based stats.
Identities = 83/258 (32%), Positives = 131/258 (50%), Gaps = 16/258 (6%)
Query: 1 MKTETEMFDVILQTAKAL-QVYAVAMSGSRSNPNATKDEFQDYDVVYIV--EDLHALVAD 57
M+T+ E+F +IL AK + AV + GSR+NPN +D+F DYD+ + + ++L + +
Sbjct: 6 MRTQKEIFALILDFAKRTDSIRAVTLEGSRANPNIKQDKFCDYDISFFLNAKNLESFKNN 65
Query: 58 LAWLERFGERVIEQHV---------LLDHRRLYLMLFEDGNRIDLTLCPKEHIKEWVDSE 108
WL+ FG ++ Q L + +L+LF+DG RIDL+L P I+ + D+E
Sbjct: 66 EEWLKIFGNILMLQKPESMELYPPDLREGWFSFLVLFDDGVRIDLSLIPLADIEWYKDNE 125
Query: 109 ADFTVLDDPQGLFAPY-APTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYA 167
VL D F P P+ ++ P + F CNE +W+ K I R L+ A
Sbjct: 126 RLMRVLLDKDNQFMPINEPSDSAFFIKPLTKQSFLDCCNELYWLYVCTHKDILRGELLLA 185
Query: 168 TDHLYGICQQELLKLLAWQVAADKG--TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQK 225
HL + ++ LL LL+W+VA + +GK YK+L +L ++ K D K
Sbjct: 186 NAHL-AMMREGLLILLSWRVALRQNNFAFSLGKEYKFLPHFLEPKERKTLYKCYKLGDLK 244
Query: 226 KITKSLFATMDFFHKEAQ 243
+ K+L FF K A+
Sbjct: 245 QAQKTLKIMEKFFAKNAR 262
>gi|149181905|ref|ZP_01860393.1| aminoglycoside 6-adenylyltransferase [Bacillus sp. SG-1]
gi|148850344|gb|EDL64506.1| aminoglycoside 6-adenylyltransferase [Bacillus sp. SG-1]
Length = 294
Score = 115 bits (287), Expect = 4e-24, Method: Composition-based stats.
Identities = 84/281 (29%), Positives = 134/281 (47%), Gaps = 14/281 (4%)
Query: 1 MKTETEMFDVILQTAKALQ-VYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
++TE EM ++IL TA + + AV M+GSR+NPN KD FQDYD+VY+V++ + +
Sbjct: 2 LRTEQEMMNLILNTANEDERIRAVYMNGSRTNPNVPKDIFQDYDIVYVVKETAPFIEEKE 61
Query: 60 WLERFGERVIEQH------VLLDHRRL-----YLMLFEDGNRIDLTLCPKEHIKE-WVDS 107
W+ FGE ++ Q + +H+ YLMLF DGNRIDL + E + E ++
Sbjct: 62 WIGAFGELLMIQEPDKLDKMAGEHKDFTKSYGYLMLFTDGNRIDLQIQSLECMNERYLSD 121
Query: 108 EADFTVLDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYA 167
+ +LD L T Y + + CN+FWW V KGI R+ L YA
Sbjct: 122 KLTIPLLDKDNYLPPIPEATDVDYHVKKPTNGQYFGCCNDFWWCQQNVAKGIWRDELPYA 181
Query: 168 TDHLYGICQQELLKLLAWQVAADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKK 226
I ++ L ++++W + V GK KY +LP K + + +
Sbjct: 182 KFMFESIIRRNLDEMVSWWIGTKTDFKVSPGKLGKYYKNFLPESYWKMYRDTYADWNYEN 241
Query: 227 ITKSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEYAKE 267
+ +LF + F A+ + F Y + + M Y ++
Sbjct: 242 MWDALFTAGNLFRILAKEVADTLSFTYPYDDDKNMSNYLQQ 282
>gi|76787192|ref|YP_330559.1| aminoglycoside 6-adenylyltransferase, putative [Streptococcus
agalactiae A909]
gi|76562249|gb|ABA44833.1| aminoglycoside 6-adenylyltransferase, putative [Streptococcus
agalactiae A909]
Length = 284
Score = 107 bits (266), Expect = 1e-21, Method: Composition-based stats.
Identities = 67/216 (31%), Positives = 117/216 (54%), Gaps = 9/216 (4%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+ E E+++++L A + ++ AV ++GSR+NPN KD+FQDYD+V++ + +++D
Sbjct: 1 MRDEQEIYNLVLNIANRDKRIEAVLLNGSRANPNVPKDDFQDYDIVFVTNFIEDIISDTY 60
Query: 60 WLERFGERVIEQHVLLDHRRL------YLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTV 113
+ ++FG+ +I Q ++ YLM F+D RIDL L E +++++D +
Sbjct: 61 YHKKFGDILIMQKPNEFRNKMEYNCFAYLMQFQDLTRIDLRLIKPEFLEDYLDDAFSKVL 120
Query: 114 LDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYG 173
LD Y T S + +K NE +WVS YVVKGI RN ++Y+ +
Sbjct: 121 LDKKNKYLDYNFERSALYETKQLSEDEINKILNEIYWVSTYVVKGIARNDIIYSEFMISN 180
Query: 174 ICQQELLKLLAWQVAADK--GTVDVGKNYKYLFQYL 207
+ +KLL ++ +K ++ GK K + QY+
Sbjct: 181 PIKNAFIKLLKQKILIEKELDSLSFGKLDKDILQYI 216
>gi|77406703|ref|ZP_00783743.1| streptomycin resistance protein [Streptococcus agalactiae H36B]
gi|77174698|gb|EAO77527.1| streptomycin resistance protein [Streptococcus agalactiae H36B]
Length = 228
Score = 105 bits (263), Expect = 2e-21, Method: Composition-based stats.
Identities = 67/216 (31%), Positives = 117/216 (54%), Gaps = 9/216 (4%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+ E E+++++L A + ++ AV ++GSR+NPN KD+FQDYD+V++ + +++D
Sbjct: 1 MRDEQEIYNLVLNIANRDKRIEAVLLNGSRANPNVPKDDFQDYDIVFVTNFIEDIISDTY 60
Query: 60 WLERFGERVIEQHVLLDHRRL------YLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTV 113
+ ++FG+ +I Q ++ YLM F+D RIDL L E +++++D +
Sbjct: 61 YHKKFGDILIMQKPNEFRNKMEYNCFAYLMQFQDLTRIDLRLIKPEFLEDYLDDAFSKVL 120
Query: 114 LDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYG 173
LD Y T S + +K NE +WVS YVVKGI RN ++Y+ +
Sbjct: 121 LDKKNKYLDYNFERSALYETKQLSEDEINKILNEIYWVSTYVVKGIARNDIIYSEFMISN 180
Query: 174 ICQQELLKLLAWQVAADK--GTVDVGKNYKYLFQYL 207
+ +KLL ++ +K ++ GK K + QY+
Sbjct: 181 PIKNAFIKLLKQKILIEKELDSLSFGKLDKDILQYI 216
>gi|22538164|ref|NP_689015.1| streptomycin resistance protein [Streptococcus agalactiae 2603V/R]
gi|25012025|ref|NP_736420.1| hypothetical protein gbs1987 [Streptococcus agalactiae NEM316]
gi|76798595|ref|ZP_00780824.1| Aminoglycoside 6-adenylyltransferase [Streptococcus agalactiae
18RS21]
gi|77413862|ref|ZP_00790040.1| streptomycin resistance protein [Streptococcus agalactiae 515]
gi|22535073|gb|AAN00888.1|AE014283_7 streptomycin resistance protein [Streptococcus agalactiae 2603V/R]
gi|24413568|emb|CAD47646.1| Unknown [Streptococcus agalactiae NEM316]
gi|76586060|gb|EAO62589.1| Aminoglycoside 6-adenylyltransferase [Streptococcus agalactiae
18RS21]
gi|77160102|gb|EAO71235.1| streptomycin resistance protein [Streptococcus agalactiae 515]
Length = 284
Score = 105 bits (263), Expect = 2e-21, Method: Composition-based stats.
Identities = 67/216 (31%), Positives = 116/216 (53%), Gaps = 9/216 (4%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+ E E+++++L A + ++ AV ++GSR+NPN KD+FQDYD+V++ + +++D
Sbjct: 1 MRDEQEIYNLVLNIANQDKRIEAVLLNGSRANPNVPKDDFQDYDIVFVTNFIEDIISDTN 60
Query: 60 WLERFGERVIEQHVLLDHRRL------YLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTV 113
+ ++FG+ +I Q + YLM F+D RIDL L E +++++D +
Sbjct: 61 YHKKFGDILIMQKPNEFRNKTEYNCFAYLMQFQDLTRIDLRLIKPEFLEDYLDDAFSKVL 120
Query: 114 LDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYG 173
LD Y T S + +K NE +WVS YVVKGI RN ++Y+ +
Sbjct: 121 LDKKNKYLDYNFERSSLYETKQLSEDEINKILNEIYWVSTYVVKGIARNDIIYSEFMISN 180
Query: 174 ICQQELLKLLAWQVAADK--GTVDVGKNYKYLFQYL 207
+ +KLL ++ +K ++ GK K + QY+
Sbjct: 181 PIKNAFIKLLKQKILIEKELDSLSFGKLDKDILQYI 216
>gi|77408031|ref|ZP_00784780.1| streptomycin resistance protein [Streptococcus agalactiae COH1]
gi|77173393|gb|EAO76513.1| streptomycin resistance protein [Streptococcus agalactiae COH1]
Length = 284
Score = 105 bits (261), Expect = 4e-21, Method: Composition-based stats.
Identities = 67/216 (31%), Positives = 116/216 (53%), Gaps = 9/216 (4%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+ E E+++++L A + ++ AV ++GSR+NPN KD+FQDYD+V++ + +++D
Sbjct: 1 MRDEQEIYNLVLNIANQDKRIEAVLLNGSRANPNVPKDDFQDYDIVFVTNFIEDIISDTN 60
Query: 60 WLERFGERVIEQHVLLDHRRL------YLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTV 113
+ ++FG+ +I Q + YLM F+D RIDL L E +++++D +
Sbjct: 61 YHKKFGDILIMQKPNEFRNKTEYNCFAYLMQFQDLTRIDLRLIKPEFLEDYLDDAFSKVL 120
Query: 114 LDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYG 173
LD Y T S + +K NE +WVS YVVKGI RN ++Y+ +
Sbjct: 121 LDKKNKYLDYNFERSSLYETKQLSEDEINKILNEIYWVSTYVVKGIARNDIMYSEFMISN 180
Query: 174 ICQQELLKLLAWQVAADK--GTVDVGKNYKYLFQYL 207
+ +KLL ++ +K ++ GK K + QY+
Sbjct: 181 PIKNAFIKLLKQKILIEKELDSLSFGKLDKDILQYI 216
>gi|50880298|emb|CAD35323.1| streptomycin resistance protein [Campylobacter jejuni]
Length = 237
Score = 103 bits (257), Expect = 1e-20, Method: Composition-based stats.
Identities = 60/184 (32%), Positives = 101/184 (54%), Gaps = 4/184 (2%)
Query: 81 YLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQG-LFAPYAPTPKRYWTAPASAT 139
Y+M F+D N+IDLTL P E +K++++ + V+ D G + PT Y SA
Sbjct: 24 YIMYFDDYNKIDLTLLPLEELKDYLNGDKLMQVILDKDGRIDRDVVPTDIDYHVRKPSAR 83
Query: 140 DFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKG-TVDVGK 198
++D CNEFW V+ YVVKG+ R +++A DHL I + ELL++++W+V + G + VGK
Sbjct: 84 EYDDCCNEFWNVTPYVVKGLCRKEILFAIDHLNEIVRHELLRMISWKVGIETGFQLSVGK 143
Query: 199 NYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFSLKTGFHYDKETA 258
NYK++ +Y+ + K + + + ++L F + + + + HYD
Sbjct: 144 NYKFIDRYISEDLWKRLLSTYRMDSCENVWEALLLCHQLFREVSGEVAER--LHYDYPEY 201
Query: 259 EKMI 262
+K I
Sbjct: 202 DKNI 205
>gi|77411979|ref|ZP_00788309.1| streptomycin resistance protein [Streptococcus agalactiae CJB111]
gi|77162005|gb|EAO72986.1| streptomycin resistance protein [Streptococcus agalactiae CJB111]
Length = 201
Score = 102 bits (255), Expect = 2e-20, Method: Composition-based stats.
Identities = 62/197 (31%), Positives = 106/197 (53%), Gaps = 7/197 (3%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+ E E+++++L A + ++ AV ++GSR+NPN KD+FQDYD+V++ + +++D
Sbjct: 1 MRDEQEIYNLVLNIANQDKRIEAVLLNGSRANPNVPKDDFQDYDIVFVTNFIEDIISDTN 60
Query: 60 WLERFGERVIEQHVLLDHRRL------YLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTV 113
+ ++FG+ +I Q + YLM F+D RIDL L E +++++D +
Sbjct: 61 YHKKFGDILIMQKPNEFRNKTEYNCFAYLMQFQDLTRIDLRLIKPEFLEDYLDDAFSKVL 120
Query: 114 LDDPQGLFAPYAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYG 173
LD Y T S + +K NE +WVS YVVKGI RN ++Y+ +
Sbjct: 121 LDKKNKYLDYNFERSSLYETKQLSEDEINKILNEIYWVSTYVVKGIARNDIIYSEFMISN 180
Query: 174 ICQQELLKLLAWQVAAD 190
+ +KLL ++ D
Sbjct: 181 PIKNAFIKLLKQKILID 197
>gi|121633835|ref|YP_976073.1| truncated streptomycin resistance protein [Enterococcus faecium]
gi|121490894|emb|CAL36530.1| truncated streptomycin resistance protein [Enterococcus faecium]
Length = 188
Score = 101 bits (251), Expect = 6e-20, Method: Composition-based stats.
Identities = 60/185 (32%), Positives = 94/185 (50%), Gaps = 11/185 (5%)
Query: 1 MKTETEMFDVILQTA-KALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
M+TE E+ ++ + A + + + + GSR+N N KD+FQDYD + V D+ ++ +
Sbjct: 1 MRTENEILSLVSEFAYQQSNIKIITLEGSRTNKNIKKDKFQDYDFTFFVSDVDYFTSEES 60
Query: 60 WLERFGERVIEQHVL--------LDHRRLYLMLFEDGNRIDLTLCPKEHIKEWV-DSEAD 110
WL FGE + Q LD+ Y+M F+DG ++D+TL + + + DS+
Sbjct: 61 WLSLFGELLFIQKPEDMELFPPDLDYGYSYIMYFKDGIKMDITLINLKDLNRYFNDSDGL 120
Query: 111 FTVLDDPQGLFAP-YAPTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATD 169
+L D L P YW + +F CNEFW VS YV KG+ R +++A D
Sbjct: 121 VKILVDKDNLVTKEIVPDDSNYWLKKPTEREFHDCCNEFWSVSTYVAKGVFRREILFALD 180
Query: 170 HLYGI 174
H I
Sbjct: 181 HFNNI 185
>gi|47420254|gb|AAT27400.1| aminoglycoside adenyltransferase [Enterococcus faecium]
gi|47420256|gb|AAT27401.1| aminoglycoside adenyltransferase [Enterococcus faecalis]
gi|48857051|gb|AAT47132.1| aminoglycoside adenyltransferase [Enterococcus faecium]
gi|48857053|gb|AAT47133.1| aminoglycoside adenyltransferase [Enterococcus faecalis]
Length = 186
Score = 99.8 bits (247), Expect = 1e-19, Method: Composition-based stats.
Identities = 55/160 (34%), Positives = 89/160 (55%), Gaps = 2/160 (1%)
Query: 81 YLMLFEDGNRIDLTLCPKEHIKEWVDSEADFTVLDDPQ-GLFAPYAPTPKRYWTAPASAT 139
YLMLF+D N+IDLTL P E + ++ + VL D + PT Y SA
Sbjct: 17 YLMLFDDYNKIDLTLLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAR 76
Query: 140 DFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAADKG-TVDVGK 198
++D CNEFW V+ YV+KG+ R +++A DH I + ELL++++W+V + G + VGK
Sbjct: 77 EYDDCCNEFWNVTPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGK 136
Query: 199 NYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFF 238
NYK++ +Y+ + ++ + + I ++LF F
Sbjct: 137 NYKFIERYISEDLWEKLLSTYRMDSYENIWEALFLCHQLF 176
>gi|285308|pir||S25259 streptomycin resistance protein - Bacteroides sp. transposon Tn4551
gi|154971|gb|AAA27459.1| streptomycin adenyltransferase [Transposon Tn4551]
Length = 287
Score = 78.6 bits (192), Expect = 3e-13, Method: Composition-based stats.
Identities = 74/283 (26%), Positives = 127/283 (44%), Gaps = 23/283 (8%)
Query: 1 MKTETEMFDVILQ-TAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
MK E I++ + K V + ++ S NP A DEF D D+ ++ ED ++D +
Sbjct: 1 MKVREEKLRTIIEWSEKNEDVRVLLLTSSLVNPLALVDEFSDLDIEFVFEDNTNYISDKS 60
Query: 60 WLERFGERVI---EQHVLLDHRR-LYLMLFEDGNRIDLTLCPK-EHIKEWVDSE------ 108
W +FG + E +H+ + ++L+EDG ++D L K + IKE + E
Sbjct: 61 WTLKFGNPIAMIEEDESCFNHKHAMKMLLYEDGVKVDFKLYSKSKFIKETQEKELPEDWD 120
Query: 109 ADFTVLDDPQGLFAPY-APTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYA 167
+ +L D G+ PT + S +F N+FWW + YV K + R+ + YA
Sbjct: 121 IGYKILIDKDGITKQMLKPTYQISIIKKPSEKEFQNLINDFWWDTTYVAKCLVRDEIFYA 180
Query: 168 TDHLYGICQQE-LLKLLAWQVAADKGTVDVGKNY-----KYLFQYLPAEKEKEFTALLDF 221
+ + E L+ L+ W +A++ Y KYL Q + A+ E+ F+
Sbjct: 181 KFMSETVIRTEYLIPLIEWHIASEHNWNITTNKYGRLFKKYLNQEMWAKTEQTFSG---- 236
Query: 222 SDQKKITKSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEY 264
SD K+ +LF+ D + S K + Y + + +Y
Sbjct: 237 SDIKENWTALFSMTDLVSEIGTELSKKLEYKYPDKLENDIRKY 279
>gi|57118035|gb|AAW34160.1| adenyltransferase [Campylobacter jejuni]
Length = 171
Score = 73.9 bits (180), Expect = 1e-11, Method: Composition-based stats.
Identities = 36/109 (33%), Positives = 63/109 (57%), Gaps = 1/109 (0%)
Query: 131 YWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQVAAD 190
Y SA ++D CNEFW V+ YV+KG+ R +++A DH I + ELL++++W+V +
Sbjct: 9 YHVRKPSAREYDDCCNEFWNVTPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIE 68
Query: 191 KG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFF 238
G + VGKNYK++ +Y+ + ++ + + I ++LF F
Sbjct: 69 TGFKLSVGKNYKFIERYISEDLWEKLLSTYRMDSYENIWEALFLCHQLF 117
>gi|15072724|emb|CAC47931.1| aminoglycoside 6-adenylyltransferase [Bacteroides thetaiotaomicron]
Length = 278
Score = 69.3 bits (168), Expect = 2e-10, Method: Composition-based stats.
Identities = 74/281 (26%), Positives = 123/281 (43%), Gaps = 28/281 (9%)
Query: 1 MKTETEMFDVILQ-TAKALQVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLA 59
MK E I++ + K V + ++ S NP A DEF D D+ ++ ED ++D +
Sbjct: 1 MKVREEKLRTIIEWSEKNEDVRVLLLTSSLVNPLALVDEFSDLDIEFVFEDNTNYISDKS 60
Query: 60 WLERFGERV--IEQHVLLDHRRLYLMLFEDGNRIDLTLCPK-EHIKEWVDSE------AD 110
W +FG + IE+ D + EDG ++D L K + IKE + E
Sbjct: 61 WTLKFGNPIAMIEE----DESATF---HEDGVKVDFKLYSKSKFIKETQEKELPEDWDIG 113
Query: 111 FTVLDDPQGLFAPY-APTPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATD 169
+ +L D G+ PT + S +F N+FWW + YV K + R+ + YA
Sbjct: 114 YKILIDKDGITKQMLKPTYQISIIKKPSEKEFQNLINDFWWDTTYVAKCLVRDEIFYAKF 173
Query: 170 HLYGICQQE-LLKLLAWQVAADKGTVDVGKNY-----KYLFQYLPAEKEKEFTALLDFSD 223
+ + E L+ L+ W +A++ Y KYL Q + A+ E+ F+ SD
Sbjct: 174 MSETVIRTEYLIPLIEWHIASEHNWNITTNKYGRLFKKYLNQEMWAKTEQTFSG----SD 229
Query: 224 QKKITKSLFATMDFFHKEAQAFSLKTGFHYDKETAEKMIEY 264
K+ +LF+ D + S K + Y + + +Y
Sbjct: 230 IKENWTALFSMTDLVSEIGTELSKKLEYKYPDKLENDIRKY 270
>gi|89099969|ref|ZP_01172840.1| aminoglycoside 6-adenylyltransferase [Bacillus sp. NRRL B-14911]
gi|89085361|gb|EAR64491.1| aminoglycoside 6-adenylyltransferase [Bacillus sp. NRRL B-14911]
Length = 291
Score = 65.1 bits (157), Expect = 4e-09, Method: Composition-based stats.
Identities = 57/250 (22%), Positives = 105/250 (42%), Gaps = 12/250 (4%)
Query: 19 QVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIE--QHVLLD 76
++ A + GSR+ DE+ D D+V IVE+ A + D WL + G+ + ++ +
Sbjct: 22 KIRAALIVGSRARTEVPADEYSDLDLVAIVENPSAFLNDTDWLGKIGKHYLTFLENTAVG 81
Query: 77 HRRLYLMLFEDGNRIDLTLCPKEHIKEW-VDSE------ADFTVLDDPQGLFAPYAPTPK 129
+ +LFE+G +D P + E D E VL D G
Sbjct: 82 GGKERRVLFEEGLDVDFAFFPVSALPELEQDPEPLGVFAKGVRVLFDKDGTVTALVHQAP 141
Query: 130 RYWTAP--ASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQV 187
+ AP + + + ++FW+ + K I R L+ A + L++L+ Q
Sbjct: 142 KNLPAPQMPGSEEIRNAIHDFWYHAVLAAKKIRRGELLDAKSICDSYMKHLLMQLVRTQT 201
Query: 188 AADKG-TVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAFS 246
+KG D ++ ++ E + L +++ + ++L TM FF + A+
Sbjct: 202 KLNKGLAFDTWHGNRFFEKWADPETVSAYKNLYGVYEEEDVWRALHNTMSFFRETAKDVC 261
Query: 247 LKTGFHYDKE 256
+K HY +E
Sbjct: 262 VKMDLHYPEE 271
>gi|37525410|ref|NP_928754.1| hypothetical protein plu1458 [Photorhabdus luminescens subsp.
laumondii TTO1]
gi|36784838|emb|CAE13751.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii
TTO1]
Length = 283
Score = 62.4 bits (150), Expect = 3e-08, Method: Composition-based stats.
Identities = 59/256 (23%), Positives = 114/256 (44%), Gaps = 15/256 (5%)
Query: 19 QVYAVAMSGSRSNPNATKDEFQDYDVVYIVEDLHALVADLAWLERFGERVIEQHVLLDHR 78
++ V +GSR+ NA D+F D D+ I L+ + W ++ G+ ++ H+ +
Sbjct: 20 RIDTVIQTGSRAR-NARVDKFSDLDIELIGSGTDELIGNDLWFKQLGDVMVALHLANEKE 78
Query: 79 R-----LYLMLFEDGNRIDLTLCPKEHIKEWVDSEAD------FTVLDDPQGLFAPYAP- 126
L++F G ++D TL + +K+ D + VL D GL
Sbjct: 79 DEPDWPTCLVVFNGGRKVDFTLASVKRLKDMKQRGLDELYQRGYKVLLDKTGLTNGLPEI 138
Query: 127 TPKRYWTAPASATDFDKSCNEFWWVSAYVVKGIHRNHLVYATDHLYGICQQELLKLLAWQ 186
T + + S+T+F+++ EFW+ + V I R L +A + + LL ++ W
Sbjct: 139 THQLTKSYIPSSTEFNENLREFWFEATQVPVYITRGDLWHARMRDNEM-KDLLLAMMEWY 197
Query: 187 VA-ADKGTVDVGKNYKYLFQYLPAEKEKEFTALLDFSDQKKITKSLFATMDFFHKEAQAF 245
V+ G DV N +L ++LP + K + +++ ++L T + + + +
Sbjct: 198 VSIKSDGKTDVWYNGHHLHEWLPEKFSKHIQGIFSSYGKEEAIRALLETTELYSEISAEV 257
Query: 246 SLKTGFHYDKETAEKM 261
+ GF +D E K+
Sbjct: 258 AEMKGFEFDSELPSKV 273
Database: nr
Posted date: Sep 17, 2007 11:41 AM
Number of letters in database: 999,999,834
Number of sequences in database: 2,976,859
Database: /nucleus1/users/jsaw/ncbi/db/nr.01
Posted date: Sep 17, 2007 11:48 AM
Number of letters in database: 894,087,890
Number of sequences in database: 2,493,262
Lambda K H
0.320 0.134 0.407
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,054,492,045
Number of Sequences: 5470121
Number of extensions: 46120196
Number of successful extensions: 96654
Number of sequences better than 1.0e-05: 73
Number of HSP's better than 0.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 96414
Number of HSP's gapped (non-prelim): 73
length of query: 277
length of database: 1,894,087,724
effective HSP length: 131
effective length of query: 146
effective length of database: 1,177,501,873
effective search space: 171915273458
effective search space used: 171915273458
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 129 (54.3 bits)