BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= SGO_0241
(339 letters)
Database: nr
5,470,121 sequences; 1,894,087,724 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157075507|gb|ABV10190.1| phosphomevalonate kinase [Strep... 643 0.0
gi|125717209|ref|YP_001034342.1| Phosphomevalonate kinase, ... 588 e-166
gi|25011436|ref|NP_735831.1| hypothetical protein gbs1394 [... 344 6e-93
gi|76798604|ref|ZP_00780832.1| phosphomevalonate kinase [St... 343 7e-93
gi|22537471|ref|NP_688322.1| phosphomevalonate kinase [Stre... 343 7e-93
gi|24379382|ref|NP_721337.1| putative phosphomevalonate kin... 342 3e-92
gi|55822531|ref|YP_140972.1| phosphomevalonate kinase [Stre... 337 5e-91
gi|55820640|ref|YP_139082.1| phosphomevalonate kinase [Stre... 336 2e-90
gi|15900306|ref|NP_344910.1| phosphomevalonate kinase [Stre... 335 2e-90
gi|15902384|ref|NP_357934.1| Phosphomevalonate kinase [Stre... 334 6e-90
gi|149012127|ref|ZP_01833236.1| 6-phosphogluconate dehydrog... 333 1e-89
gi|148994465|ref|ZP_01823666.1| phosphomevalonate kinase [S... 332 3e-89
gi|149003485|ref|ZP_01828359.1| 6-phosphogluconate dehydrog... 332 3e-89
gi|149018081|ref|ZP_01834540.1| 6-phosphogluconate dehydrog... 332 3e-89
gi|116627445|ref|YP_820064.1| Phosphomevalonate kinase [Str... 331 5e-89
gi|148988142|ref|ZP_01819605.1| 6-phosphogluconate dehydrog... 331 5e-89
gi|148983787|ref|ZP_01817106.1| 6-phosphogluconate dehydrog... 329 1e-88
gi|9937409|gb|AAG02457.1|AF290099_3 phosphomevalonate kinas... 327 5e-88
gi|50914047|ref|YP_060019.1| Phosphomevalonate kinase [Stre... 327 7e-88
gi|15674903|ref|NP_269077.1| phosphomevalonate kinase [Stre... 327 9e-88
gi|94988370|ref|YP_596471.1| phosphomevalonate kinase [Stre... 327 9e-88
gi|139473957|ref|YP_001128673.1| phosphomevalonate kinase [... 326 1e-87
gi|94994172|ref|YP_602270.1| Phosphomevalonate kinase [Stre... 326 1e-87
gi|19745946|ref|NP_607082.1| phosphomevalonate kinase [Stre... 325 2e-87
gi|56808905|ref|ZP_00366614.1| COG1577: Mevalonate kinase [... 325 3e-87
gi|21910133|ref|NP_664401.1| phosphomevalonate kinase [Stre... 324 4e-87
gi|94990251|ref|YP_598351.1| Phosphomevalonate kinase [Stre... 324 4e-87
gi|21465779|pdb|1K47|A Chain A, Crystal Structure Of The St... 322 2e-86
gi|71903329|ref|YP_280132.1| phosphomevalonate kinase [Stre... 320 6e-86
gi|9937388|gb|AAG02442.1|AF290093_3 phosphomevalonate kinas... 166 1e-39
gi|29375486|ref|NP_814640.1| phosphomevalonate kinase [Ente... 166 2e-39
gi|146317947|ref|YP_001197659.1| Mevalonate kinase [Strepto... 164 6e-39
gi|28378414|ref|NP_785306.1| phosphomevalonate kinase [Lact... 163 1e-38
gi|116333506|ref|YP_795033.1| Mevalonate kinase [Lactobacil... 163 2e-38
gi|116494593|ref|YP_806327.1| Phosphomevalonate kinase [Lac... 162 3e-38
gi|90961660|ref|YP_535576.1| Phosphomevalonate kinase [Lact... 160 1e-37
gi|81097383|ref|ZP_00875671.1| Gram positive phosphomevalon... 159 3e-37
gi|81428517|ref|YP_395517.1| Phosphomevalonate kinase [Lact... 154 7e-36
gi|69246579|ref|ZP_00604009.1| Gram positive phosphomevalon... 149 3e-34
gi|116492690|ref|YP_804425.1| Phosphomevalonate kinase [Ped... 148 5e-34
gi|92088323|ref|ZP_01273285.1| Gram positive phosphomevalon... 141 5e-32
gi|73663429|ref|YP_302210.1| phosphomevalonate kinase [Stap... 137 9e-31
gi|70727399|ref|YP_254315.1| phosphomevalonate kinase [Stap... 136 2e-30
gi|9937374|gb|AAG02432.1|AF290089_3 phosphomevalonate kinas... 136 2e-30
gi|9937366|gb|AAG02426.1|AF290087_3 phosphomevalonate kinas... 135 3e-30
gi|21282276|ref|NP_645364.1| phosphomevalonate kinase [Stap... 135 3e-30
gi|15923582|ref|NP_371116.1| phosphomevalonate kinase [Stap... 135 3e-30
gi|87160430|ref|YP_493277.1| phosphomevalonate kinase [Stap... 134 1e-29
gi|27467281|ref|NP_763918.1| phosphomevalonate kinase [Stap... 132 4e-29
gi|42519132|ref|NP_965062.1| mevalonate kinase [Lactobacill... 130 2e-28
gi|116629676|ref|YP_814848.1| Phosphomevalonate kinase [Lac... 128 4e-28
gi|58337454|ref|YP_194039.1| phosphomevalonate kinase [Lact... 127 1e-27
gi|116514013|ref|YP_812919.1| Phosphomevalonate kinase [Lac... 121 7e-26
gi|9695272|dbj|BAB07792.1| phosphomevalonate kinase [Strept... 120 9e-26
gi|104773997|ref|YP_618977.1| Phosphomevalonate kinase [Lac... 120 1e-25
gi|57753872|dbj|BAD86802.1| phosphomevalonate kinase [Strep... 119 3e-25
gi|40882373|dbj|BAD07377.1| phosphomevalonate kinase [Actin... 115 4e-24
gi|16799091|ref|NP_469359.1| hypothetical protein lin0012 [... 114 6e-24
gi|153164835|ref|ZP_01926010.1| phosphomevalonate kinase [L... 114 7e-24
gi|46906237|ref|YP_012626.1| phosphomevalonate kinase [List... 114 7e-24
gi|16802060|ref|NP_463545.1| hypothetical protein lmo0012 [... 113 2e-23
gi|47097295|ref|ZP_00234853.1| phosphomevalonate kinase [Li... 113 2e-23
gi|116871435|ref|YP_848216.1| phosphomevalonate kinase [Lis... 113 2e-23
gi|153197979|ref|ZP_01942149.1| phosphomevalonate kinase [L... 110 1e-22
gi|9711348|dbj|BAB07819.1| phosphomevalonate kinase [Kitasa... 109 3e-22
gi|15212072|emb|CAC51372.1| phosphomevalonate kinase [Lacto... 107 8e-22
gi|54024178|ref|YP_118420.1| putative phosphomevalonate kin... 106 2e-21
gi|23097682|ref|NP_691148.1| phosphomevalonate kinase [Ocea... 105 4e-21
gi|153799375|gb|ABS50446.1| NapT4 [Streptomyces aculeolatus] 102 3e-20
gi|86475802|dbj|BAE78979.1| phosphomevalonate kinase [Strep... 91 1e-16
gi|124520336|ref|ZP_01695503.1| phosphomevalonate kinase [B... 90 2e-16
gi|116618482|ref|YP_818853.1| Phosphomevalonate kinase [Leu... 86 4e-15
gi|118618816|ref|YP_907148.1| phosphomevalonate kinase [Myc... 85 6e-15
gi|116491122|ref|YP_810666.1| Phosphomevalonate kinase [Oen... 75 6e-12
gi|47093022|ref|ZP_00230801.1| phosphomevalonate kinase [Li... 64 2e-08
gi|47093023|ref|ZP_00230802.1| phosphomevalonate kinase [Li... 62 7e-08
gi|108763233|ref|YP_633172.1| putative phosphomevalonate ki... 55 9e-06
>gi|157075507|gb|ABV10190.1| phosphomevalonate kinase [Streptococcus gordonii str. Challis
substr. CH1]
Length = 339
Score = 643 bits (1659), Expect = 0.0, Method: Composition-based stats.
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASL 60
MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASL
Sbjct: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASL 60
Query: 61 EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKA 120
EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKA
Sbjct: 61 EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKA 120
Query: 121 MAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEV 180
MAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEV
Sbjct: 121 MAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEV 180
Query: 181 DLPQLLAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVD 240
DLPQLLAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVD
Sbjct: 181 DLPQLLAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVD 240
Query: 241 ALERALLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGD 300
ALERALLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGD
Sbjct: 241 ALERALLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGD 300
Query: 301 CGIALSFDAASSKQLIQAWQEAGIELLYRERMGRDEPES 339
CGIALSFDAASSKQLIQAWQEAGIELLYRERMGRDEPES
Sbjct: 301 CGIALSFDAASSKQLIQAWQEAGIELLYRERMGRDEPES 339
>gi|125717209|ref|YP_001034342.1| Phosphomevalonate kinase, putative [Streptococcus sanguinis SK36]
gi|125497126|gb|ABN43792.1| Phosphomevalonate kinase, putative [Streptococcus sanguinis SK36]
Length = 339
Score = 588 bits (1516), Expect = e-166, Method: Composition-based stats.
Identities = 307/339 (90%), Positives = 317/339 (93%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASL 60
MK SARVQTCGKLYLAGEYAVLT GQPAIIKAIPIYMT EIQAA YRLTSDMFEHSASL
Sbjct: 1 MKTSARVQTCGKLYLAGEYAVLTTGQPAIIKAIPIYMTAEIQAASAYRLTSDMFEHSASL 60
Query: 61 EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKA 120
EPDPDYALIQET+ MN YL LGYQLQPFSLKISGKMER+GKK GIGSSGSVVILT+KA
Sbjct: 61 EPDPDYALIQETVAVMNDYLQVLGYQLQPFSLKISGKMERDGKKFGIGSSGSVVILTIKA 120
Query: 121 MAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEV 180
MAALYELDL+P+LLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL+ KRM +V
Sbjct: 121 MAALYELDLEPKLLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELVRKRMGKV 180
Query: 181 DLPQLLAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVD 240
L QLLAEDW F+IRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFL GSRTQVD
Sbjct: 181 YLQQLLAEDWGFEIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLTGSRTQVD 240
Query: 241 ALERALLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGD 300
ALE+ALLAG+K AIQSSMEKASQLLE LSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGD
Sbjct: 241 ALEKALLAGDKLAIQSSMEKASQLLETLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGD 300
Query: 301 CGIALSFDAASSKQLIQAWQEAGIELLYRERMGRDEPES 339
CGIALSFD ASS QLIQAWQEAGIELLYRERMG DEPES
Sbjct: 301 CGIALSFDVASSNQLIQAWQEAGIELLYRERMGHDEPES 339
>gi|25011436|ref|NP_735831.1| hypothetical protein gbs1394 [Streptococcus agalactiae NEM316]
gi|76788436|ref|YP_329965.1| phosphomevalonate kinase [Streptococcus agalactiae A909]
gi|77406864|ref|ZP_00783892.1| phosphomevalonate kinase [Streptococcus agalactiae H36B]
gi|77411188|ref|ZP_00787540.1| phosphomevalonate kinase [Streptococcus agalactiae CJB111]
gi|77414065|ref|ZP_00790234.1| phosphomevalonate kinase [Streptococcus agalactiae 515]
gi|24412974|emb|CAD47053.1| Unknown [Streptococcus agalactiae NEM316]
gi|76563493|gb|ABA46077.1| phosphomevalonate kinase [Streptococcus agalactiae A909]
gi|77159863|gb|EAO71005.1| phosphomevalonate kinase [Streptococcus agalactiae 515]
gi|77162806|gb|EAO73765.1| phosphomevalonate kinase [Streptococcus agalactiae CJB111]
gi|77174537|gb|EAO77378.1| phosphomevalonate kinase [Streptococcus agalactiae H36B]
Length = 330
Score = 344 bits (882), Expect = 6e-93, Method: Composition-based stats.
Identities = 183/327 (55%), Positives = 244/327 (74%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPD 65
+VQT GKLY+AGEYA+L GQ AI+K IPIYMT A +Y L SDMF ++ASL+PD
Sbjct: 3 KVQTGGKLYIAGEYAILYPGQVAILKNIPIYMTALATFADNYSLYSDMFNYTASLQPDKQ 62
Query: 66 YALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALY 125
Y+LIQETI M +L+ G ++P L+I+GK+ER G K GIGSSGSVV+LT+KAMAALY
Sbjct: 63 YSLIQETILLMEEWLINFGKNIKPIHLEITGKLERYGLKFGIGSSGSVVVLTIKAMAALY 122
Query: 126 ELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQL 185
E+++ +LLFKL++YVLLKRGDNGSMGD+ACIA+E LI Y +FDR +SK ++ L Q+
Sbjct: 123 EIEMPSDLLFKLSAYVLLKRGDNGSMGDIACIAYEHLISYSAFDRRAVSKMIETKPLEQV 182
Query: 186 LAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERA 245
L +W ++I I+ L MDFLVGWT QP+ISK+++N VKS I++ FL + QV L A
Sbjct: 183 LEAEWGYRITKIQASLEMDFLVGWTMQPSISKEMINIVKSTITQRFLDDTNYQVVQLLSA 242
Query: 246 LLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIAL 305
G+K AI+ +E+ S LL L P+IYTD+L+ LKEA++GL+ V KSSG+GGGDCGIA+
Sbjct: 243 FKEGDKEAIKRCLEEISLLLFNLHPSIYTDKLQKLKEASKGLDIVTKSSGSGGGDCGIAI 302
Query: 306 SFDAASSKQLIQAWQEAGIELLYRERM 332
SF+ ++ LI+ W+ AGIELL +E +
Sbjct: 303 SFNKNDNQTLIKRWESAGIELLSKETL 329
>gi|76798604|ref|ZP_00780832.1| phosphomevalonate kinase [Streptococcus agalactiae 18RS21]
gi|76586038|gb|EAO62568.1| phosphomevalonate kinase [Streptococcus agalactiae 18RS21]
Length = 330
Score = 343 bits (881), Expect = 7e-93, Method: Composition-based stats.
Identities = 182/327 (55%), Positives = 245/327 (74%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPD 65
+VQT GKLY+AGEYA+L GQ AI+K +PIYMT A +Y L SDMF ++ASL+PD
Sbjct: 3 KVQTGGKLYIAGEYAILYPGQVAILKNVPIYMTALATFADNYSLYSDMFNYTASLQPDKQ 62
Query: 66 YALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALY 125
Y+LIQETI M +L+ G ++P L+I+GK+ER G K GIGSSGSVV+LT+KAMAALY
Sbjct: 63 YSLIQETILLMEEWLINFGKNIKPIHLEITGKLERYGLKFGIGSSGSVVVLTIKAMAALY 122
Query: 126 ELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQL 185
E+++ +LLFKL++YVLLKRGDNGSMGD+ACIA+E LI Y +FDR +SK ++ L Q+
Sbjct: 123 EIEMPSDLLFKLSAYVLLKRGDNGSMGDIACIAYEHLISYSAFDRRAVSKMIETKPLEQV 182
Query: 186 LAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERA 245
L +W ++I I+ L MDFLVGWT QP+ISK+++N VKS I++ FL ++ QV L A
Sbjct: 183 LEAEWGYRITKIQASLEMDFLVGWTMQPSISKEMINIVKSTITQRFLDDTKYQVVQLLSA 242
Query: 246 LLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIAL 305
G+K AI+ +E+ S LL L P+IYTD+L+ LKEA++GL+ V KSSG+GGGDCGIA+
Sbjct: 243 FKEGDKEAIKRCLEEISLLLFNLHPSIYTDKLQKLKEASKGLDIVTKSSGSGGGDCGIAI 302
Query: 306 SFDAASSKQLIQAWQEAGIELLYRERM 332
SF+ ++ LI+ W+ AGIELL +E +
Sbjct: 303 SFNKNDNQTLIKRWESAGIELLSKETL 329
>gi|22537471|ref|NP_688322.1| phosphomevalonate kinase [Streptococcus agalactiae 2603V/R]
gi|77409168|ref|ZP_00785880.1| phosphomevalonate kinase [Streptococcus agalactiae COH1]
gi|22534349|gb|AAN00195.1|AE014252_18 phosphomevalonate kinase [Streptococcus agalactiae 2603V/R]
gi|77172214|gb|EAO75371.1| phosphomevalonate kinase [Streptococcus agalactiae COH1]
Length = 330
Score = 343 bits (881), Expect = 7e-93, Method: Composition-based stats.
Identities = 182/327 (55%), Positives = 245/327 (74%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPD 65
+VQT GKLY+AGEYA+L GQ AI+K +PIYMT A +Y L SDMF ++ASL+PD
Sbjct: 3 KVQTGGKLYIAGEYAILYPGQVAILKNVPIYMTALATFADNYSLYSDMFNYTASLQPDKQ 62
Query: 66 YALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALY 125
Y+LIQETI M +L+ G ++P L+I+GK+ER G K GIGSSGSVV+LT+KAMAALY
Sbjct: 63 YSLIQETILLMEEWLINFGKNIKPIHLEITGKLERYGLKFGIGSSGSVVVLTIKAMAALY 122
Query: 126 ELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQL 185
E+++ +LLFKL++YVLLKRGDNGSMGD+ACIA+E LI Y +FDR +SK ++ L Q+
Sbjct: 123 EIEMPSDLLFKLSAYVLLKRGDNGSMGDIACIAYEHLISYSAFDRRAVSKMIETKPLEQV 182
Query: 186 LAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERA 245
L +W ++I I+ L MDFLVGWT QP+ISK+++N VKS I++ FL ++ QV L A
Sbjct: 183 LEAEWGYRITKIQALLEMDFLVGWTMQPSISKEMINIVKSTITQRFLDDTKYQVVQLLSA 242
Query: 246 LLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIAL 305
G+K AI+ +E+ S LL L P+IYTD+L+ LKEA++GL+ V KSSG+GGGDCGIA+
Sbjct: 243 FKEGDKEAIKRCLEEISLLLFNLHPSIYTDKLQKLKEASKGLDIVTKSSGSGGGDCGIAI 302
Query: 306 SFDAASSKQLIQAWQEAGIELLYRERM 332
SF+ ++ LI+ W+ AGIELL +E +
Sbjct: 303 SFNKNDNQTLIKRWESAGIELLSKETL 329
>gi|24379382|ref|NP_721337.1| putative phosphomevalonate kinase [Streptococcus mutans UA159]
gi|24377311|gb|AAN58643.1|AE014934_7 putative phosphomevalonate kinase [Streptococcus mutans UA159]
Length = 332
Score = 342 bits (876), Expect = 3e-92, Method: Composition-based stats.
Identities = 179/327 (54%), Positives = 243/327 (74%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPD 65
+V+T GKLY+AGEYA+LT Q AIIK IPIYMT I++A + + SDMF + + D +
Sbjct: 6 QVKTGGKLYIAGEYAILTPSQSAIIKNIPIYMTATIKSAKEISIWSDMFAYCVGMAADSN 65
Query: 66 YALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALY 125
Y+LIQETI + +L L PFSL+I+G++ R+GKK GIGSSGSV ILTLKA++ Y
Sbjct: 66 YSLIQETITVLANFLGKEIADLSPFSLEINGELGRDGKKFGIGSSGSVTILTLKALSRFY 125
Query: 126 ELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQL 185
+LDL + +FKLA+Y L+KRGDNGSMGDLACIA+++L+Y+ +FDR+L+ + DL +
Sbjct: 126 QLDLSTDTIFKLAAYTLIKRGDNGSMGDLACIAYDNLVYFTAFDRQLVRTWIVSDDLRTV 185
Query: 186 LAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERA 245
L DW ++I + P +A DFLVGWTKQP+IS +VN VKS+I+ SFL S+ V+ L +
Sbjct: 186 LERDWGYRISVLYPKIACDFLVGWTKQPSISNKMVNLVKSSITPSFLKVSQENVEKLSQG 245
Query: 246 LLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIAL 305
LL G+K I+ S+ +SQLLE L+PAIYT+RL+ LK A +GL+ +AKSSG+GGGDCGIAL
Sbjct: 246 LLNGQKDVIKESLATSSQLLENLNPAIYTERLRQLKAAEKGLDVIAKSSGSGGGDCGIAL 305
Query: 306 SFDAASSKQLIQAWQEAGIELLYRERM 332
SF S L++ WQ+AGIELLY+E++
Sbjct: 306 SFKDRDSHLLVERWQKAGIELLYQEKL 332
>gi|55822531|ref|YP_140972.1| phosphomevalonate kinase [Streptococcus thermophilus CNRZ1066]
gi|55738516|gb|AAV62157.1| phosphomevalonate kinase [Streptococcus thermophilus CNRZ1066]
Length = 331
Score = 337 bits (865), Expect = 5e-91, Method: Composition-based stats.
Identities = 181/322 (56%), Positives = 232/322 (72%), Gaps = 3/322 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+T GKLY+AGEY+VLT GQ A+I+ IPI+M+ EI+ A +LTSDMF++S EPD +Y
Sbjct: 11 VKTGGKLYIAGEYSVLTPGQTALIQFIPIFMSAEIKKAQTTQLTSDMFDYSVDREPDVNY 70
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQE ++NT+ G L L I+GK+ER+G K GIGSSGSVV+LTLKA+AA +
Sbjct: 71 ALIQE---ALNTFEAYCGENLPALDLSITGKLERDGVKFGIGSSGSVVVLTLKALAASLQ 127
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
DL ++LFKLASY LLK+GDNGSMGDLACI +EDL+ YRSFDR I++ +D++ L +LL
Sbjct: 128 KDLSKDILFKLASYTLLKQGDNGSMGDLACIVYEDLVSYRSFDRAKIAELIDQMTLSELL 187
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW ++I + L FLVGWTKQ AISKD+V VKS IS +L + V +AL
Sbjct: 188 EIDWGYRISPVVSVLKARFLVGWTKQAAISKDMVKMVKSRISSKYLSETEVTVQDAIKAL 247
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S++ S LE LSP IY D+LK LKEA +GL+ +AKSSGAGGGDCGIA +
Sbjct: 248 ETGNKNLLKRSLQTVSDQLESLSPDIYVDKLKKLKEAEQGLDAIAKSSGAGGGDCGIAFT 307
Query: 307 FDAASSKQLIQAWQEAGIELLY 328
FD AS L++ WQ+AGIELLY
Sbjct: 308 FDQASRDILVERWQQAGIELLY 329
>gi|55820640|ref|YP_139082.1| phosphomevalonate kinase [Streptococcus thermophilus LMG 18311]
gi|55736625|gb|AAV60267.1| phosphomevalonate kinase [Streptococcus thermophilus LMG 18311]
Length = 331
Score = 336 bits (861), Expect = 2e-90, Method: Composition-based stats.
Identities = 180/322 (55%), Positives = 232/322 (72%), Gaps = 3/322 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+T GKLY+AGEY+VLT GQ A+I+ IPI+M+ EI+ A +LTSDMF++S EPD +Y
Sbjct: 11 VKTGGKLYIAGEYSVLTPGQTALIQFIPIFMSAEIKKAQTTQLTSDMFDYSVDREPDVNY 70
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ+ ++NT+ G L L I+GK+ER+G K GIGSSGSVV+LTLKA+AA +
Sbjct: 71 ALIQD---ALNTFEAYCGENLPALDLSITGKLERDGVKFGIGSSGSVVVLTLKALAASLQ 127
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
DL ++LFKLASY LLK+GDNGSMGDLACI +EDL+ YRSFDR I++ +D++ L +LL
Sbjct: 128 KDLSKDILFKLASYTLLKQGDNGSMGDLACIVYEDLVSYRSFDRAKIAELIDQMTLSELL 187
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW ++I + L FLVGWTKQ AISKD+V VKS IS +L + V +AL
Sbjct: 188 EIDWGYRISPVVSVLKARFLVGWTKQAAISKDMVKMVKSRISSKYLSETEVAVQDAIKAL 247
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S++ S LE LSP IY D+LK LKEA +GL+ +AKSSGAGGGDCGIA +
Sbjct: 248 ETGNKNLLKRSLQTVSDQLESLSPDIYVDKLKKLKEAEQGLDAIAKSSGAGGGDCGIAFT 307
Query: 307 FDAASSKQLIQAWQEAGIELLY 328
FD AS L++ WQ+AGIELLY
Sbjct: 308 FDQASRDILVERWQQAGIELLY 329
>gi|15900306|ref|NP_344910.1| phosphomevalonate kinase [Streptococcus pneumoniae TIGR4]
gi|111657159|ref|ZP_01407939.1| hypothetical protein SpneT_02001624 [Streptococcus pneumoniae
TIGR4]
gi|148996794|ref|ZP_01824512.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP11-BS70]
gi|14971853|gb|AAK74550.1| phosphomevalonate kinase [Streptococcus pneumoniae TIGR4]
gi|147757369|gb|EDK64408.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP11-BS70]
Length = 335
Score = 335 bits (860), Expect = 2e-90, Method: Composition-based stats.
Identities = 190/330 (57%), Positives = 239/330 (72%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSL+I GKMEREGKK G+GSSGSVV+L +KA+ ALY+
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKFGLGSSGSVVVLVVKALLALYD 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ + ELLFKL S VLLKRGDNGSMGDLACI EDL+ Y+SFDR+ ++ ++E +L +L
Sbjct: 124 VSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLVLYQSFDRQKVAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLTSSKETVTSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ I +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKSEKIIDQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQTVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S+K L W + GIELLY+ER+G D+
Sbjct: 304 FDAQSTKTLKNRWADLGIELLYQERIGHDD 333
>gi|15902384|ref|NP_357934.1| Phosphomevalonate kinase [Streptococcus pneumoniae R6]
gi|116517118|ref|YP_815861.1| phosphomevalonate kinase [Streptococcus pneumoniae D39]
gi|15457898|gb|AAK99144.1| Phosphomevalonate kinase [Streptococcus pneumoniae R6]
gi|116077694|gb|ABJ55414.1| phosphomevalonate kinase [Streptococcus pneumoniae D39]
Length = 335
Score = 334 bits (856), Expect = 6e-90, Method: Composition-based stats.
Identities = 191/330 (57%), Positives = 237/330 (71%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSL I GKMEREGKK G+GSSGSVV+L +KA+ ALY
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLAIYGKMEREGKKFGLGSSGSVVVLVVKALLALYN 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
L + LLFKL S VLLKRGDNGSMGDLACIA EDL+ Y+SFDR+ ++ ++E +L +L
Sbjct: 124 LSVDQNLLFKLTSAVLLKRGDNGSMGDLACIAAEDLVLYQSFDRQKVAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLTSSKETVVSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ I +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S+K L W + GIELLY+ER+G D+
Sbjct: 304 FDAQSTKTLKNRWADLGIELLYQERIGHDD 333
>gi|149012127|ref|ZP_01833236.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP19-BS75]
gi|147763729|gb|EDK70663.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP19-BS75]
Length = 335
Score = 333 bits (854), Expect = 1e-89, Method: Composition-based stats.
Identities = 189/330 (57%), Positives = 239/330 (72%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSL+I GKMEREGKK G+GSSGSVV+L +KA+ ALY+
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKFGLGSSGSVVVLVVKALLALYD 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ + ELLFKL S VLLKRGDNGSMGDLACI EDL+ Y+SFDR+ ++ ++E +L +L
Sbjct: 124 VSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLVLYQSFDRQKVAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLSSSKETVVSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ + +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S+K L W + GIELLY+ER+G D+
Sbjct: 304 FDAESTKTLKNRWADLGIELLYQERIGHDD 333
>gi|148994465|ref|ZP_01823666.1| phosphomevalonate kinase [Streptococcus pneumoniae SP9-BS68]
gi|149006135|ref|ZP_01829864.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP18-BS74]
gi|147762491|gb|EDK69452.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP18-BS74]
gi|147927214|gb|EDK78249.1| phosphomevalonate kinase [Streptococcus pneumoniae SP9-BS68]
Length = 335
Score = 332 bits (850), Expect = 3e-89, Method: Composition-based stats.
Identities = 189/330 (57%), Positives = 237/330 (71%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSLKI GKMEREGKK G+GSSGSVV+L +KA+ ALY
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKFGLGSSGSVVVLVVKALLALYN 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
L + LLFKL S VLLKRGDNGSMGDLACI EDL+ Y+SFDR+ ++ ++E +L +L
Sbjct: 124 LSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLVLYQSFDRQKVAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLSSSKETVVSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ + +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S++ L W + GIELLY+ER+G D+
Sbjct: 304 FDAQSTETLKNRWADLGIELLYQERIGHDD 333
>gi|149003485|ref|ZP_01828359.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP14-BS69]
gi|147758421|gb|EDK65420.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP14-BS69]
Length = 335
Score = 332 bits (850), Expect = 3e-89, Method: Composition-based stats.
Identities = 190/330 (57%), Positives = 236/330 (71%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSLKI GKMEREGKK G+GSSGSVV+L +KA+ ALY
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKFGLGSSGSVVVLVVKALLALYN 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
L + LLFKL S VLLKRGDNGSMGDLACI EDL+ Y+SFDR+ + ++E +L +L
Sbjct: 124 LSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLVVYQSFDRQKAAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLSSSKETVVSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ + +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S+K L W + GIELLY+ER+G D+
Sbjct: 304 FDAQSTKTLKNRWADLGIELLYQERIGHDD 333
>gi|149018081|ref|ZP_01834540.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP23-BS72]
gi|147931645|gb|EDK82623.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP23-BS72]
Length = 335
Score = 332 bits (850), Expect = 3e-89, Method: Composition-based stats.
Identities = 189/330 (57%), Positives = 237/330 (71%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLTPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSLKI GKMEREGKK G+GSSGSVV+L +KA+ ALY
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKFGLGSSGSVVVLVVKALLALYN 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
L + LLFKL S VLLKRGDNGSMGDLACI EDL+ Y+SFDR+ ++ ++E +L +L
Sbjct: 124 LSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLVLYQSFDRQKVAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLSSSKETVVSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ + +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S++ L W + GIELLY+ER+G D+
Sbjct: 304 FDAQSTETLKNRWADLGIELLYQERIGHDD 333
>gi|116627445|ref|YP_820064.1| Phosphomevalonate kinase [Streptococcus thermophilus LMD-9]
gi|116100722|gb|ABJ65868.1| Phosphomevalonate kinase [Streptococcus thermophilus LMD-9]
Length = 331
Score = 331 bits (848), Expect = 5e-89, Method: Composition-based stats.
Identities = 179/322 (55%), Positives = 230/322 (71%), Gaps = 3/322 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+T GKLY+AGEY+VLT GQ A+I+ IPI+M+ EI+ A +LTSDMF++S EPD +Y
Sbjct: 11 VKTGGKLYIAGEYSVLTPGQTALIQFIPIFMSAEIKKAQTTQLTSDMFDYSVDREPDVNY 70
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQE ++NT+ G L L I+GK+ER+G K GIGSSGSVV+LTLKA+AA +
Sbjct: 71 ALIQE---ALNTFEAYCGENLPALDLSITGKLERDGVKFGIGSSGSVVVLTLKALAASLQ 127
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
DL ++LFKLASY LLK+GDNGSMGDLACI +EDL+ Y SFDR I++ +D++ L +LL
Sbjct: 128 KDLSKDILFKLASYTLLKQGDNGSMGDLACIVYEDLVSYHSFDRAKIAELIDQMTLSELL 187
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW ++I + L FLVGWTKQ AISKD+V VKS IS +L + V +AL
Sbjct: 188 EIDWGYRISPVVSELKARFLVGWTKQAAISKDMVKMVKSRISSKYLSETEVAVQDAIKAL 247
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S++ S LE LSP IY D+LK LKEA + L+ +AKSSGAGGGDCGIA +
Sbjct: 248 ETGNKNLLKRSLQTVSDQLESLSPDIYVDKLKKLKEAEQRLDAIAKSSGAGGGDCGIAFT 307
Query: 307 FDAASSKQLIQAWQEAGIELLY 328
FD AS L++ WQ+AGIELLY
Sbjct: 308 FDQASRDILVERWQQAGIELLY 329
>gi|148988142|ref|ZP_01819605.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP6-BS73]
gi|147926606|gb|EDK77679.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP6-BS73]
Length = 335
Score = 331 bits (848), Expect = 5e-89, Method: Composition-based stats.
Identities = 190/330 (57%), Positives = 236/330 (71%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSLKI GKMEREGKK G+GSSGSVV+L +KA+ ALY
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKFGLGSSGSVVVLVVKALLALYN 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
L + LLFKL S VLLKRGDNGSMGDLACI EDL+ Y+SFDR+ + ++E +L +L
Sbjct: 124 LSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLVLYQSFDRQKAAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLSSSKETVVSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ + +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S+K L W + GIELLY+ER+G D+
Sbjct: 304 FDAQSTKTLKNRWADLGIELLYQERIGHDD 333
>gi|148983787|ref|ZP_01817106.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP3-BS71]
gi|147923934|gb|EDK75046.1| 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae
SP3-BS71]
Length = 335
Score = 329 bits (844), Expect = 1e-88, Method: Composition-based stats.
Identities = 189/330 (57%), Positives = 236/330 (71%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSLKI GKMEREGKK G+GSSGSVV+L +KA+ ALY
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKFGLGSSGSVVVLVVKALLALYN 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
L + LLFKL S VLLKRGDNGSMGDLACI EDL+ Y+SFDR+ + ++E +L +L
Sbjct: 124 LSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLVLYQSFDRQKAAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLSSSKETVVSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ + +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S++ L W + GIELLY+ER+G D+
Sbjct: 304 FDAQSTETLKNRWADLGIELLYQERIGHDD 333
>gi|9937409|gb|AAG02457.1|AF290099_3 phosphomevalonate kinase [Streptococcus pneumoniae]
Length = 336
Score = 327 bits (839), Expect = 5e-88, Method: Composition-based stats.
Identities = 189/331 (57%), Positives = 237/331 (71%), Gaps = 1/331 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIYM EI + YR+ SDMF+ + L P+PDY
Sbjct: 4 VKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSYRIYSDMFDFAVDLRPNPDY 63
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI M +L G L+PFSLKI GKMEREGKK G+GSSGSVV+L +KA+ ALY
Sbjct: 64 SLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKFGLGSSGSVVVLVVKALLALYN 123
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
L + LLFKL S VLLKRGDNGSMGDLACI EDL+ Y+SFDR+ + ++E +L +L
Sbjct: 124 LSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLVLYQSFDRQKAAAWLEEENLATVL 183
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S +V Q+K I+++FL S+ V +L AL
Sbjct: 184 ERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQQIKQNINQNFLSSSKETVVSLVEAL 243
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ + +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 244 EQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 303
Query: 307 FDAASSKQLIQ-AWQEAGIELLYRERMGRDE 336
FDA SS+ ++ W + GIELLY+ER+G D+
Sbjct: 304 FDAQSSRNTLKNRWADLGIELLYQERIGHDD 334
>gi|50914047|ref|YP_060019.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS10394]
gi|50903121|gb|AAT86836.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS10394]
Length = 353
Score = 327 bits (838), Expect = 7e-88, Method: Composition-based stats.
Identities = 180/332 (54%), Positives = 230/332 (69%), Gaps = 1/332 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+LT GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 22 VQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAHIQLASDMFAHKAGMTPDASY 81
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I+GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 82 ALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 141
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK+GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 142 ITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 201
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 202 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 261
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 262 QEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 321
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGR-DEP 337
F+ + LI WQEA I LLY+ER G D+P
Sbjct: 322 FNQNARDTLISKWQEADIALLYQERWGENDQP 353
>gi|15674903|ref|NP_269077.1| phosphomevalonate kinase [Streptococcus pyogenes M1 GAS]
gi|71910497|ref|YP_282047.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS5005]
gi|13622043|gb|AAK33798.1| phosphomevalonate kinase [Streptococcus pyogenes M1 GAS]
gi|71853279|gb|AAZ51302.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS5005]
Length = 335
Score = 327 bits (837), Expect = 9e-88, Method: Composition-based stats.
Identities = 178/330 (53%), Positives = 229/330 (69%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+LT GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 6 VQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAHIQLASDMFSHKAGMTPDASY 65
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I+GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 66 ALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 125
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK+GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 126 ITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 185
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 186 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 245
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 246 QEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 305
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
F+ + LI WQEA I LLY+ER G ++
Sbjct: 306 FNQDARDTLISKWQEADIALLYQERWGEND 335
>gi|94988370|ref|YP_596471.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS9429]
gi|94992252|ref|YP_600351.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS2096]
gi|94541878|gb|ABF31927.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS9429]
gi|94545760|gb|ABF35807.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS2096]
Length = 353
Score = 327 bits (837), Expect = 9e-88, Method: Composition-based stats.
Identities = 180/332 (54%), Positives = 230/332 (69%), Gaps = 1/332 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+LT GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 22 VQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAHIQLASDMFAHKAGMTPDASY 81
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I+GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 82 ALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 141
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK+GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 142 ITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 201
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 202 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 261
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 262 QEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 321
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGR-DEP 337
F+ + LI WQEA I LLY+ER G D+P
Sbjct: 322 FNQDARDTLISKWQEADIALLYQERWGENDQP 353
>gi|139473957|ref|YP_001128673.1| phosphomevalonate kinase [Streptococcus pyogenes str. Manfredo]
gi|134272204|emb|CAM30450.1| phosphomevalonate kinase [Streptococcus pyogenes str. Manfredo]
Length = 337
Score = 326 bits (836), Expect = 1e-87, Method: Composition-based stats.
Identities = 180/332 (54%), Positives = 228/332 (68%), Gaps = 1/332 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+LT GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 6 VQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAHIQLASDMFAHKAGMTPDASY 65
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 66 ALIQATVKTFADYLGQSIDQLEPFSLIIMGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 125
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 126 ITLTPELLFKLAAYTLLKHGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 185
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 186 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 245
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 246 QEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 305
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGR-DEP 337
F+ + LI WQEA I LLY+ER G D+P
Sbjct: 306 FNQNARDTLISKWQEADIALLYQERWGENDQP 337
>gi|94994172|ref|YP_602270.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS10750]
gi|94547680|gb|ABF37726.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS10750]
Length = 351
Score = 326 bits (836), Expect = 1e-87, Method: Composition-based stats.
Identities = 178/330 (53%), Positives = 229/330 (69%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+LT GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 22 VQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAHIQLASDMFAHKAGMTPDASY 81
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I+GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 82 ALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 141
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK+GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 142 ITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 201
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 202 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 261
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 262 QEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 321
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
F+ + LI WQEA I LLY+ER G ++
Sbjct: 322 FNQDARDTLISKWQEADIALLYQERWGEND 351
>gi|19745946|ref|NP_607082.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS8232]
gi|19748104|gb|AAL97581.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS8232]
Length = 337
Score = 325 bits (833), Expect = 2e-87, Method: Composition-based stats.
Identities = 179/332 (53%), Positives = 228/332 (68%), Gaps = 1/332 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+LT GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 6 VQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEITPAAHIQLASDMFAHKAGMTPDASY 65
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 66 ALIQATVKTFADYLGQSIDQLEPFSLIIMGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 125
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 126 ITLTPELLFKLAAYTLLKHGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 185
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
++W + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 186 VKNWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 245
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 246 QEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 305
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGR-DEP 337
F+ + LI WQEA I LLY+ER G D+P
Sbjct: 306 FNQNARDTLISKWQEADIALLYQERWGENDQP 337
>gi|56808905|ref|ZP_00366614.1| COG1577: Mevalonate kinase [Streptococcus pyogenes M49 591]
Length = 337
Score = 325 bits (832), Expect = 3e-87, Method: Composition-based stats.
Identities = 179/332 (53%), Positives = 229/332 (68%), Gaps = 1/332 (0%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+LT GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 6 VQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAHIQLASDMFSHKAGMTPDASY 65
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I+GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 66 ALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 125
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK+GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 126 ITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 185
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 186 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 245
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 246 QESHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 305
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGR-DEP 337
F+ + LI WQEA I LLY+ER G D+P
Sbjct: 306 FNQNARDTLISKWQEADIALLYQERWGENDQP 337
>gi|21910133|ref|NP_664401.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS315]
gi|28896168|ref|NP_802518.1| putative phosphomevalonate kinase [Streptococcus pyogenes SSI-1]
gi|9937402|gb|AAG02452.1|AF290097_3 phosphomevalonate kinase [Streptococcus pyogenes]
gi|21904325|gb|AAM79204.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS315]
gi|28811418|dbj|BAC64351.1| putative phosphomevalonate kinase [Streptococcus pyogenes SSI-1]
Length = 335
Score = 324 bits (831), Expect = 4e-87, Method: Composition-based stats.
Identities = 177/330 (53%), Positives = 228/330 (69%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+L GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 6 VQTGGKLYLTGEYAILIPGQKALIHFIPLMMTAEISPAAHIQLASDMFSHKAGMTPDASY 65
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I+GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 66 ALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 125
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK+GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 126 ITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 185
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 186 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 245
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 246 QEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 305
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
F+ + LI WQEA I LLY+ER G ++
Sbjct: 306 FNQDARDTLISKWQEADIALLYQERWGEND 335
>gi|94990251|ref|YP_598351.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS10270]
gi|94543759|gb|ABF33807.1| Phosphomevalonate kinase [Streptococcus pyogenes MGAS10270]
Length = 351
Score = 324 bits (831), Expect = 4e-87, Method: Composition-based stats.
Identities = 177/330 (53%), Positives = 228/330 (69%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+L GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 22 VQTGGKLYLTGEYAILIPGQKALIHFIPLMMTAEISPAAHIQLASDMFSHKAGMTPDASY 81
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I+GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 82 ALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 141
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK+GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 142 ITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 201
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 202 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 261
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L PAIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 262 QEGHKEELKKSLAGASHLLKELHPAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 321
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
F+ + LI WQEA I LLY+ER G ++
Sbjct: 322 FNQDARDTLISKWQEADIALLYQERWGEND 351
>gi|21465779|pdb|1K47|A Chain A, Crystal Structure Of The Streptococcus Pneumoniae
Phosphomevalonate Kinase (Pmk)
gi|21465780|pdb|1K47|B Chain B, Crystal Structure Of The Streptococcus Pneumoniae
Phosphomevalonate Kinase (Pmk)
gi|21465781|pdb|1K47|C Chain C, Crystal Structure Of The Streptococcus Pneumoniae
Phosphomevalonate Kinase (Pmk)
gi|21465782|pdb|1K47|D Chain D, Crystal Structure Of The Streptococcus Pneumoniae
Phosphomevalonate Kinase (Pmk)
gi|21465783|pdb|1K47|E Chain E, Crystal Structure Of The Streptococcus Pneumoniae
Phosphomevalonate Kinase (Pmk)
gi|21465784|pdb|1K47|F Chain F, Crystal Structure Of The Streptococcus Pneumoniae
Phosphomevalonate Kinase (Pmk)
Length = 337
Score = 322 bits (825), Expect = 2e-86, Method: Composition-based stats.
Identities = 186/330 (56%), Positives = 231/330 (70%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
V+TCGKLY AGEYA+L GQ A+IK IPIY EI + YR+ SD F+ + L P+PDY
Sbjct: 6 VKTCGKLYWAGEYAILEPGQLALIKDIPIYXRAEIAFSDSYRIYSDXFDFAVDLRPNPDY 65
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
+LIQETI +L G L+PFSL I GK EREGKK G+GSSGSVV+L +KA+ ALY
Sbjct: 66 SLIQETIALXGDFLAVRGQNLRPFSLAIYGKXEREGKKFGLGSSGSVVVLVVKALLALYN 125
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
L + LLFKL S VLLKRGDNGS GDLACIA EDL+ Y+SFDR+ ++ ++E +L +L
Sbjct: 126 LSVDQNLLFKLTSAVLLKRGDNGSXGDLACIAAEDLVLYQSFDRQKVAAWLEEENLATVL 185
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
DW F I +KP L DFLVGWTK+ A+S V Q+K I+++FL S+ V +L AL
Sbjct: 186 ERDWGFSISQVKPTLECDFLVGWTKEVAVSSHXVQQIKQNINQNFLTSSKETVVSLVEAL 245
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G+ I +E AS+LLE LS IYT L+ LKEA++ L VAKSSGAGGGDCGIALS
Sbjct: 246 EQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQLKEASQDLQAVAKSSGAGGGDCGIALS 305
Query: 307 FDAASSKQLIQAWQEAGIELLYRERMGRDE 336
FDA S+K L W + GIELLY+ER+G D+
Sbjct: 306 FDAQSTKTLKNRWADLGIELLYQERIGHDD 335
>gi|71903329|ref|YP_280132.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS6180]
gi|71802424|gb|AAX71777.1| phosphomevalonate kinase [Streptococcus pyogenes MGAS6180]
Length = 353
Score = 320 bits (821), Expect = 6e-86, Method: Composition-based stats.
Identities = 176/325 (54%), Positives = 225/325 (69%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDPDY 66
VQT GKLYL GEYA+LT GQ A+I IP+ MT EI A +L SDMF H A + PD Y
Sbjct: 22 VQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAAHIQLASDMFSHKAGMTPDASY 81
Query: 67 ALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYE 126
ALIQ T+ + YL QL+PFSL I+GKMER+GKK GIGSSGSV +LTLKA++A Y+
Sbjct: 82 ALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGKKFGIGSSGSVTLLTLKALSAYYQ 141
Query: 127 LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLL 186
+ L PELLFKLA+Y LLK+GDNGSMGD+ACIA++ L+ Y SFDRE +S + + L +LL
Sbjct: 142 ITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVAYTSFDREQVSNWLQTMPLKKLL 201
Query: 187 AEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISESFLIGSRTQVDALERAL 246
+DW + I+ I+P L DFLVGWTK PAIS+ ++ QV ++I+ +FL S + AL
Sbjct: 202 VKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQVTASITPAFLRTSYQLTQSAMVAL 261
Query: 247 LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALS 306
G K ++ S+ AS LL+ L AIY +L L A + + VAKSSG+GGGDCGIAL+
Sbjct: 262 QEGHKEELKKSLAGASHLLKELHSAIYHPKLVTLVAACQKQDAVAKSSGSGGGDCGIALA 321
Query: 307 FDAASSKQLIQAWQEAGIELLYRER 331
F+ + LI WQEA I LLY+ER
Sbjct: 322 FNQNARDTLISKWQEADIALLYQER 346
>gi|9937388|gb|AAG02442.1|AF290093_3 phosphomevalonate kinase [Enterococcus faecalis]
Length = 368
Score = 166 bits (421), Expect = 1e-39, Method: Composition-based stats.
Identities = 120/346 (34%), Positives = 178/346 (51%), Gaps = 26/346 (7%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMT---------GEIQAAP----DYRLTSDM 53
V T GKL++AGEYAV+ G PAII A+ ++T G IQ+A R T
Sbjct: 4 VTTPGKLFIAGEYAVVEPGHPAIIVAVDQFVTVTVEETTDEGSIQSAQYSSLPIRWTRRN 63
Query: 54 FEHSASLEPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMERE-GKKLGIGSSGS 112
E + +P + + I Y +L + LK++ +++ G+K G+GSSG+
Sbjct: 64 GELVLDIRENP-FHYVLAAIHLTEKYAQEQNKELSFYHLKVTSELDSSNGRKYGLGSSGA 122
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
V + T+KA+ Y+L L+ E +FKL++ L NGS GD+A + I + +FD +
Sbjct: 123 VTVGTVKALNIFYDLGLENEEIFKLSALAHLAVQGNGSCGDIAASCYGGWIAFSTFDHDW 182
Query: 173 ISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV------KS 225
+++++ L LLA DW + I +K + L+GWT PA + DLV++V K
Sbjct: 183 VNQKVTTETLTDLLAMDWPELMIFPLKVPKQLRLLIGWTGSPASTSDLVDRVHQSKEEKQ 242
Query: 226 AISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLK 281
A E FL+ SR V+ + G+ IQ + K QLL LS I T+ LK L
Sbjct: 243 AAYEQFLMKSRLCVETMINGFNTGKISVIQKQITKNRQLLAELSSLTGVVIETEALKNLC 302
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
+ AE AKSSGAGGGDCGI + + L+ AW++ GI L
Sbjct: 303 DLAESYTGAAKSSGAGGGDCGIVIFRQKSGILPLMTAWEKDGITPL 348
>gi|29375486|ref|NP_814640.1| phosphomevalonate kinase [Enterococcus faecalis V583]
gi|29342946|gb|AAO80710.1| phosphomevalonate kinase [Enterococcus faecalis V583]
Length = 368
Score = 166 bits (420), Expect = 2e-39, Method: Composition-based stats.
Identities = 120/346 (34%), Positives = 178/346 (51%), Gaps = 26/346 (7%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMT---------GEIQAAP----DYRLTSDM 53
V T GKL++AGEYAV+ G PAII A+ ++T G IQ+A R T
Sbjct: 4 VTTPGKLFIAGEYAVVEPGHPAIIVAVDQFVTVTVEETTDEGSIQSAQYSSLPIRWTRRN 63
Query: 54 FEHSASLEPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMERE-GKKLGIGSSGS 112
E + +P + + I Y +L + LK++ +++ G+K G+GSSG+
Sbjct: 64 GELVLDIRENP-FHYVLAAIHLTEKYAQEQNKELSFYHLKVTSELDSSNGRKYGLGSSGA 122
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
V + T+KA+ Y+L L+ E +FKL++ L NGS GD+A + I + +FD +
Sbjct: 123 VTVGTVKALNIFYDLGLENEEIFKLSALAHLAVQGNGSCGDIAASCYGGWIAFSTFDHDW 182
Query: 173 ISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV------KS 225
+++++ L LLA DW + I +K + L+GWT PA + DLV++V K
Sbjct: 183 VNQKVATETLTDLLAMDWPELMIFPLKVPKQLRLLIGWTGSPASTSDLVDRVHQSKEEKQ 242
Query: 226 AISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLK 281
A E FL+ SR V+ + G+ IQ + K QLL LS I T+ LK L
Sbjct: 243 AAYEQFLMKSRLCVETMINGFNTGKISVIQKQITKNRQLLAELSSLTGVVIETEALKNLC 302
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
+ AE AKSSGAGGGDCGI + + L+ AW++ GI L
Sbjct: 303 DLAESYTGAAKSSGAGGGDCGIVIFRQKSGILPLMTAWEKDGITPL 348
>gi|146317947|ref|YP_001197659.1| Mevalonate kinase [Streptococcus suis 05ZYH33]
gi|146320134|ref|YP_001199845.1| Mevalonate kinase [Streptococcus suis 98HAH33]
gi|145688753|gb|ABP89259.1| Mevalonate kinase [Streptococcus suis 05ZYH33]
gi|145690940|gb|ABP91445.1| Mevalonate kinase [Streptococcus suis 98HAH33]
Length = 379
Score = 164 bits (416), Expect = 6e-39, Method: Composition-based stats.
Identities = 124/346 (35%), Positives = 180/346 (52%), Gaps = 28/346 (8%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAA----------PDYRLTSDMFE 55
+V+ GKL+LAGEYAV+ AG PA+I A+ Y+T I+ + D LT + E
Sbjct: 24 QVKIPGKLFLAGEYAVVEAGYPAVIAAVGQYLTVTIETSDQGSLHSSQKADLYLTWERKE 83
Query: 56 HSASLEPDPDYALIQETIGSMNTYLLALGYQLQ-PFSLKISGKMERE--GKKLGIGSSGS 112
+ ++ YALI+ + YL A GY +SL + ++ + G K G+GSSG+
Sbjct: 84 GAVRIQGSHPYALIESAMQVTEAYLTAKGYACHGTYSLSVQSDLDDQASGAKYGLGSSGA 143
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
V + T+KA+ Y L +KLA+ K G GS GDLA +F LI Y S DR
Sbjct: 144 VTVATVKALLTYYGHQADALLTYKLAALTQSKLGMTGSFGDLAASSFGGLIAYHSLDRSW 203
Query: 173 ISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ +M E+ L ++ DW I I+ +D LVGWT A + LV+Q++S S++
Sbjct: 204 LLGKMAELSLLDVVESDWQSLSISPIQLPQGLDLLVGWTGSAASTDSLVSQMESQKSQTE 263
Query: 231 -------FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKV 279
FL S+T V+ L A + + + ++ +LL+ + I T +L
Sbjct: 264 KEQIHSQFLADSKTCVEQLIVACQTNDSVSARQALSANRKLLQDFARGMGLVIETPQLSQ 323
Query: 280 LKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQ-AWQEAGI 324
L + A+ VAKSSGAGGGDCGI L D+ K I+ AWQEAGI
Sbjct: 324 LCDLAQTYGAVAKSSGAGGGDCGICL-VDSKEQKAAIETAWQEAGI 368
>gi|28378414|ref|NP_785306.1| phosphomevalonate kinase [Lactobacillus plantarum WCFS1]
gi|28271250|emb|CAD64154.1| phosphomevalonate kinase [Lactobacillus plantarum WCFS1]
Length = 363
Score = 163 bits (413), Expect = 1e-38, Method: Composition-based stats.
Identities = 111/345 (32%), Positives = 174/345 (50%), Gaps = 24/345 (6%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDY-RLTSDMFEHSASL----- 60
V+ GKLY+AGEYAV+ +G PAII A+ ++T I + + S+ ++ ++ +
Sbjct: 4 VKAPGKLYIAGEYAVVESGYPAIIVALNQFVTATISPSETIGSIVSEQYQENSIVWRRQG 63
Query: 61 ------EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSV 113
D + I I +Y LG +L + L I+ +++ +GKK G+GSS +V
Sbjct: 64 DAMVFDNRDNPFHYILAAINLTESYAHELGRELGVYHLGINSELDSADGKKYGLGSSAAV 123
Query: 114 VILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELI 173
+ T+KA+ Y L + LFKLA+ L NGS+GD+A + I Y SFDR+ +
Sbjct: 124 TVATVKALCQFYHLPMDKNKLFKLAAIAHLSVQGNGSLGDIAASVYGGWIAYHSFDRQWL 183
Query: 174 SKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV------KSA 226
+ + L LL W D KI + P A+ ++GWT PA + LV++V + +
Sbjct: 184 HLQQAQSSLSDLLTMPWPDLKIELLTPPAALRLMIGWTGSPASTSHLVDKVALVKAKQRS 243
Query: 227 ISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLKE 282
++FL S+ + + + IQ+ + QLL++L I T L+ + +
Sbjct: 244 EYQTFLKASKACLKRMITGFHHSDLHVIQTELRTNRQLLQKLGGFSHVTIETPLLQRMIQ 303
Query: 283 AAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
AE AK+SGAGGGDCGI L + L+ AW GIE L
Sbjct: 304 LAESAGAAAKTSGAGGGDCGIVLIDQTIDPRPLLTAWAHDGIEQL 348
>gi|116333506|ref|YP_795033.1| Mevalonate kinase [Lactobacillus brevis ATCC 367]
gi|116098853|gb|ABJ64002.1| Mevalonate kinase [Lactobacillus brevis ATCC 367]
Length = 357
Score = 163 bits (412), Expect = 2e-38, Method: Composition-based stats.
Identities = 112/344 (32%), Positives = 174/344 (50%), Gaps = 24/344 (6%)
Query: 8 QTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDY-RLTSDMFEHSASL------ 60
Q GKLY+AGEYAV+ G PAII A+ ++T I+ + DY R+ S ++ ++
Sbjct: 5 QAPGKLYIAGEYAVVEPGYPAIIVALNQFVTVTIETSRDYGRIASKQYQENSLYWQRQGT 64
Query: 61 -----EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSVV 114
D + I I Y LG L + L ++ +++ +GKK G+GSS +V
Sbjct: 65 ELVFDNRDNPFHYILSAIHLTEQYAQTLGKPLSIYHLNVNSELDSADGKKYGLGSSAAVT 124
Query: 115 ILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELIS 174
+ T+KA+ Y++ + + LFKLA+ L NGS+GD+A + I Y++FDR+ ++
Sbjct: 125 VATVKALCQFYDIPMSQDRLFKLAAIAHLDVQGNGSLGDIAASVYGGWIAYQAFDRDWLA 184
Query: 175 KRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV------KSAI 227
E+ L QLL W +I + P + ++GWT PA + LV+++ +
Sbjct: 185 SARRELSLEQLLDTQWPGLQIELLTPPEPLRLMIGWTGTPASTSHLVDKIALFKATRRKD 244
Query: 228 SESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLKEA 283
+FL SR + + + AIQ+ + QLL L+ I T LK + +
Sbjct: 245 YHTFLRESRECLQRMIDGFHHQDLNAIQTEIAVNRQLLNHLAHLSHVTIETTLLKTMCDI 304
Query: 284 AEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
AE + AKSSGAGGGDCGI + A L+ W+ GIE L
Sbjct: 305 AEHVGGAAKSSGAGGGDCGIVIINAAKDLAHLLTEWEARGIEPL 348
>gi|116494593|ref|YP_806327.1| Phosphomevalonate kinase [Lactobacillus casei ATCC 334]
gi|116104743|gb|ABJ69885.1| Phosphomevalonate kinase [Lactobacillus casei ATCC 334]
Length = 357
Score = 162 bits (410), Expect = 3e-38, Method: Composition-based stats.
Identities = 114/344 (33%), Positives = 176/344 (51%), Gaps = 24/344 (6%)
Query: 8 QTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDY-RLTSDMFEHSASL------ 60
Q GKLY+AGEYAV+ G PAII A+ ++T ++A + + S+ ++ ++
Sbjct: 5 QAPGKLYVAGEYAVVETGFPAIIVALDQFVTVTVEATKHFGSIVSEQYQENSLYWQRQGD 64
Query: 61 -----EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGIGSSGSVV 114
D + I I Y L L + L I +++ ++GKK G+GSS +V
Sbjct: 65 EMVFDNRDNPFHYILSAIKLTEQYARELDKPLALYKLYIDSQLDAKDGKKYGLGSSAAVT 124
Query: 115 ILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELIS 174
+ T+KA+A Y+L + + ++KLA+ L NGS+GD+A + I YRSFD+ ++
Sbjct: 125 VATIKALAKFYDLKMSKDQIYKLAAIAHLDVQGNGSLGDIAASVYGGWIAYRSFDKAWLA 184
Query: 175 KRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV------KSAI 227
+++ L L+ DW D I + M LVGWT PA + LV+++ K +
Sbjct: 185 AARNQMSLADLINTDWPDLSIELLTAPADMQLLVGWTGSPASTSQLVDKITLAKAKKPQL 244
Query: 228 SESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLKEA 283
FL SR ++ L +IQ+ + + +LL+ L+ AI T L+ L E
Sbjct: 245 YRDFLTASRETLEKLIDGFRNRSLSSIQAGIRRNRELLDELAHFSGVAIQTPALRQLVEL 304
Query: 284 AEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
AE AKSSGAGGGDCGI L + K L+ AW++ IE L
Sbjct: 305 AEQAGGAAKSSGAGGGDCGIVLIDSHQAIKPLLAAWRDHHIEPL 348
>gi|90961660|ref|YP_535576.1| Phosphomevalonate kinase [Lactobacillus salivarius subsp.
salivarius UCC118]
gi|90820854|gb|ABD99493.1| Phosphomevalonate kinase [Lactobacillus salivarius subsp.
salivarius UCC118]
Length = 355
Score = 160 bits (404), Expect = 1e-37, Method: Composition-based stats.
Identities = 113/342 (33%), Positives = 173/342 (50%), Gaps = 24/342 (7%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPD--------YRLTSDMFEHSA 58
V+ GKLY+AGEYAV+ GQPAI+ A+ ++ ++ + D Y+ S ++
Sbjct: 4 VKAPGKLYIAGEYAVVETGQPAILVALDQFVYVNLEKSNDLGSIISKQYKENSLYWKREG 63
Query: 59 SL----EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSV 113
+ D + I I + Y +LG +++ + LKI +++ +GKK G+GSS +V
Sbjct: 64 NQIIFDNRDNPFHYILSAINLVEEYAQSLGKKMEFYHLKIDSELDSPDGKKYGLGSSAAV 123
Query: 114 VILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELI 173
+ T+KA++ YEL+L E LFKLAS L NGS+GD+A + I Y SFD+E +
Sbjct: 124 TVATIKALSEFYELNLSKEHLFKLASIAHLNVQGNGSLGDIAASVYGGWIAYHSFDKEWL 183
Query: 174 SKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES-- 230
+ +LL +W + K+ + P ++ L+GWT PA + LV+ V + +
Sbjct: 184 KVAQRSYTISELLDLNWPNLKVTQLTPPDNLNLLIGWTGSPASTSHLVDAVALHKANNQN 243
Query: 231 ----FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERL----SPAIYTDRLKVLKE 282
FL S +D + IQ S+ +LL L S I T L L
Sbjct: 244 KYNHFLENSWKCIDTMITGFKENSLSKIQESLIYNRELLRNLASLSSVEIETPLLTKLIT 303
Query: 283 AAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGI 324
+AE AK+SGAGGGDCGI L + + + L W+E GI
Sbjct: 304 SAEKFGGAAKTSGAGGGDCGIVLIDKSMNVEPLFAYWKENGI 345
>gi|81097383|ref|ZP_00875671.1| Gram positive phosphomevalonate kinase [Streptococcus suis 89/1591]
gi|80976567|gb|EAP40162.1| Gram positive phosphomevalonate kinase [Streptococcus suis 89/1591]
Length = 359
Score = 159 bits (401), Expect = 3e-37, Method: Composition-based stats.
Identities = 124/345 (35%), Positives = 179/345 (51%), Gaps = 26/345 (7%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAA----------PDYRLTSDMFE 55
+V+ GKL+LAGEYAV+ AG PA+I A+ Y+T I+ + D LT + E
Sbjct: 4 QVKIPGKLFLAGEYAVVEAGYPAVIAAVDQYLTVTIETSDRGLLHSSQQADLYLTWERKE 63
Query: 56 HSASLEPDPDYALIQETIGSMNTYLLALGYQLQ-PFSLKISGKMERE--GKKLGIGSSGS 112
A ++ D YALI+ + YL A GY +SL + ++ + G K G+GSSG+
Sbjct: 64 GIAHVQGDHPYALIETAMQVTEAYLTAKGYACHGTYSLAVQSDLDDQTSGAKYGLGSSGA 123
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
V + T+KA+ Y L +KLA+ K G GS GDLA +F LI Y S DR
Sbjct: 124 VTVATVKALLTYYGHRPGALLAYKLAALAQTKLGMTGSFGDLAASSFGGLIAYHSLDRSW 183
Query: 173 ISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ +M E+ L L+ DW I I+ +D LVGWT A + LV+Q++S S++
Sbjct: 184 LLGKMAELSLLDLVESDWQSLSISPIQLPQGLDLLVGWTGSAASTDSLVSQMESQKSQAE 243
Query: 231 -------FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKV 279
FL S+T V+ L A + +++ + + +LL+ + I T +L
Sbjct: 244 KEQIHSWFLADSKTCVEQLIVACQTNDSASVRQGLAQNRKLLQDFARGMGLVIETPQLSQ 303
Query: 280 LKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGI 324
L + A+ VAKSSGAGGGDCGI L + +AWQEAGI
Sbjct: 304 LCDLAQTYGAVAKSSGAGGGDCGICLVDSKEQKVAIEKAWQEAGI 348
>gi|81428517|ref|YP_395517.1| Phosphomevalonate kinase [Lactobacillus sakei subsp. sakei 23K]
gi|78610159|emb|CAI55208.1| Phosphomevalonate kinase [Lactobacillus sakei subsp. sakei 23K]
Length = 367
Score = 154 bits (389), Expect = 7e-36, Method: Composition-based stats.
Identities = 108/341 (31%), Positives = 175/341 (51%), Gaps = 24/341 (7%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDY-RLTSDMFEHSASL--------- 60
GKLY+AGEYAV+ G PAII A+ ++T I+ + +Y + S ++ ++
Sbjct: 19 GKLYIAGEYAVVETGFPAIIVALNQFVTVSIEESREYGSIVSKQYQENSLYWQRQGDEMV 78
Query: 61 --EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSVVILT 117
D + I I Y G +L + L+++ ++ +GKK G+GSS +V + T
Sbjct: 79 FDNRDNPFHYILSAIKLTEQYARQAGKKLSIYHLRVNSDLDSADGKKYGLGSSAAVTVAT 138
Query: 118 LKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRM 177
+KA+ A Y+L+L + L+KLA+ L NGS+GD+A + I YRSFD++ +++
Sbjct: 139 VKALCAFYKLELTNDQLYKLAAIAHLDVQGNGSLGDIAASVYGGWIAYRSFDKQWLAETR 198
Query: 178 DEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISE------S 230
+ L +LLA W I + P + L+GWT PA + LV+++ A +E +
Sbjct: 199 PTMTLNELLAIPWPSLSIELLTPPAELSLLIGWTGSPASTSHLVDKIALAKTERQADYQN 258
Query: 231 FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLKEAAEG 286
FL S+ ++ + IQ+ + LL+ L+ AI T L+ + AE
Sbjct: 259 FLKASKACLEDMVAGFRTNNLQQIQAELRHNRALLQELADFSHVAIETPVLQKMGTLAEE 318
Query: 287 LNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
AK+SGAGGGDCGI + A + L + W++ IE L
Sbjct: 319 AGGAAKTSGAGGGDCGIVIIDRAIDTTSLFEKWRDNQIERL 359
>gi|69246579|ref|ZP_00604009.1| Gram positive phosphomevalonate kinase [Enterococcus faecium DO]
gi|9937395|gb|AAG02447.1|AF290095_3 phosphomevalonate kinase [Enterococcus faecium]
gi|68195187|gb|EAN09643.1| Gram positive phosphomevalonate kinase [Enterococcus faecium DO]
Length = 361
Score = 149 bits (375), Expect = 3e-34, Method: Composition-based stats.
Identities = 117/348 (33%), Positives = 169/348 (48%), Gaps = 30/348 (8%)
Query: 7 VQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMT---------GEIQAAP----DYRLTSDM 53
V GKLY+AGEYAV+ G PA+I A+ ++T G IQ+A R T
Sbjct: 4 VSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKVGSIQSAQYSGMPVRWTRRN 63
Query: 54 FEHSASLEPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMERE-GKKLGIGSSGS 112
E + +P + I I Y L + LK++ +++ G+K G+GSSG+
Sbjct: 64 GELVLDIRENP-FHYILAAIRLTEKYAQEKNILLSFYDLKVTSELDSSNGRKYGLGSSGA 122
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
V + T+KA+ Y L+L +FK+A+ L DNGS GD+A + I + +FD
Sbjct: 123 VTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGSCGDIAASCYGGWIAFSTFDHPW 182
Query: 173 ISKRMDEVDLPQLLAEDWDFKIRSIKPCLA---MDFLVGWTKQPAISKDLVNQV------ 223
+ ++ + + +LLA DW SI+P +A + L+GWT PA + DLV+QV
Sbjct: 183 LQEQETQHSISELLALDWPG--LSIEPLIAPEDLRLLIGWTGSPASTSDLVDQVHRSRED 240
Query: 224 KSAISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKV 279
K + FL S V+ + + IQ + K QLL LS I T L
Sbjct: 241 KMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIRKNRQLLHDLSAITGVVIETPALNK 300
Query: 280 LKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
L AE AKSSGAGGGDCGI + + L+ AW++A I L
Sbjct: 301 LCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGILPLMSAWEKAEITPL 348
>gi|116492690|ref|YP_804425.1| Phosphomevalonate kinase [Pediococcus pentosaceus ATCC 25745]
gi|116102840|gb|ABJ67983.1| Phosphomevalonate kinase [Pediococcus pentosaceus ATCC 25745]
Length = 360
Score = 148 bits (373), Expect = 5e-34, Method: Composition-based stats.
Identities = 104/345 (30%), Positives = 171/345 (49%), Gaps = 31/345 (8%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLT-----SDMFEHSASL----- 60
GKLY+AGEYA++ G A++ AI ++T ++ + +LT S ++++
Sbjct: 8 GKLYIAGEYAIVEPGNNAVLVAINQFVTASLEPS---KLTVGNIISKQYQNNVLSWRRRG 64
Query: 61 ------EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSV 113
D Y I I + + L +L+ ++L I+ ++ +GKK G+GSS +V
Sbjct: 65 SELVVDNRDNPYHYILSAISIIEELAVLLNRKLKTYNLYINSDLDSSDGKKYGLGSSAAV 124
Query: 114 VILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELI 173
+ T+K +A Y + L ELLFKLAS L NGS+GD+A + I Y+SF+R+ +
Sbjct: 125 TVATIKVVAKFYNIPLTKELLFKLASIAHLDVQGNGSLGDIAASVYGGWIAYQSFNRDWL 184
Query: 174 SKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISE--- 229
+ DL +L W KI + P + +GWT PA + DLV+QV + +
Sbjct: 185 NSMRRTKDLETILRTPWPQLKIELLTPPSDLRLYIGWTGSPASTSDLVDQVATTSYQETD 244
Query: 230 ---SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLS----PAIYTDRLKVLKE 282
FL + + ++ + + IQ + LL+ LS +I T L +
Sbjct: 245 SYHEFLTKNASCINKMIDGFRDADITVIQREITNNRHLLQELSLFSGVSIETTTLTNFCD 304
Query: 283 AAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
AE + AKSSGAGGGDCGI + ++ + ++ W++ I+ L
Sbjct: 305 IAEKFDGAAKSSGAGGGDCGIVIMPNSTKTAKMFAEWEKHDIKPL 349
>gi|92088323|ref|ZP_01273285.1| Gram positive phosphomevalonate kinase [Lactobacillus reuteri
100-23]
gi|148544142|ref|YP_001271512.1| phosphomevalonate kinase [Lactobacillus reuteri F275]
gi|91804680|gb|EAS89517.1| Gram positive phosphomevalonate kinase [Lactobacillus reuteri
100-23]
gi|148531176|gb|ABQ83175.1| phosphomevalonate kinase [Lactobacillus reuteri F275]
Length = 375
Score = 141 bits (356), Expect = 5e-32, Method: Composition-based stats.
Identities = 102/342 (29%), Positives = 167/342 (48%), Gaps = 25/342 (7%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMT----------GEI---QAAPDYRLTSDMFEHS 57
GKLY+AGEYAV+ G PAI+ A+ ++T G+I Q D + +
Sbjct: 8 GKLYIAGEYAVVENGYPAILVALDQFVTCTIEESVQEVGQIISRQYNNDQLSWRRLGDQM 67
Query: 58 ASLEPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSVVIL 116
+ D ++ I I Y L+ F++ I +++ G+K G+GSS +V +
Sbjct: 68 VVDKRDNPFSYILSAIRVTEEYARTFSRDLRIFNIHIDSQLDSANGRKYGLGSSAAVTVA 127
Query: 117 TLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKR 176
T+KA+ Y L + + +FKLA+ + NGS+GD+A + I Y SFDR+ ++++
Sbjct: 128 TVKALCRFYNLPVNKDQIFKLAAIAHFEVQGNGSLGDVAASVYGGWISYHSFDRQWLAQQ 187
Query: 177 MDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV------KSAISE 229
+DL ++ W D I S+ ++ L+GWT +PA + LV+++ +
Sbjct: 188 RKYLDLKTIIDLPWPDLNIESLTAPKNLELLIGWTGKPASTSQLVDKISLFKARRQTEYH 247
Query: 230 SFLIGSRT----QVDALERALLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAE 285
FL S++ VD R L K I+ + + QL I T+ L L + AE
Sbjct: 248 HFLEKSKSCIQRMVDGFHRQDLEAIKNEIRYNRDLLKQLGTNSGVNIETESLSKLCQIAE 307
Query: 286 GLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
AK+SGAGGGDCGI ++ ++++W + IE L
Sbjct: 308 SFGGAAKTSGAGGGDCGIVAIDSNSNFGNVLKSWAKNHIEQL 349
>gi|73663429|ref|YP_302210.1| phosphomevalonate kinase [Staphylococcus saprophyticus subsp.
saprophyticus ATCC 15305]
gi|72495944|dbj|BAE19265.1| phosphomevalonate kinase [Staphylococcus saprophyticus subsp.
saprophyticus ATCC 15305]
Length = 358
Score = 137 bits (345), Expect = 9e-31, Method: Composition-based stats.
Identities = 101/348 (29%), Positives = 169/348 (48%), Gaps = 26/348 (7%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQ--AAPDYRLTSDMFEHS-ASLEP 62
+V+ GKLY+AGEYAV G +++ A+ ++T I+ AP + S H + +
Sbjct: 3 QVKAPGKLYIAGEYAVTEPGYKSVLIAVDRFVTASIEDSNAPQGTIHSKTLHHDPVTFQR 62
Query: 63 DPDYALIQET------------IGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGIGS 109
D ++ + I Y+ + L+ F+L I ++ G K G+GS
Sbjct: 63 REDQIVVSDVHAAKQLKYVITAIEVFEQYVRSNHISLKHFNLTIDSNLDDANGHKYGLGS 122
Query: 110 SGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFD 169
S +V++ +K + YE L ++KLA +K S GD+A + + Y +FD
Sbjct: 123 SAAVLVSVVKVLNEFYETHLSNLYIYKLAVIANMKLQSLSSCGDIAVSIYTGWLAYSTFD 182
Query: 170 RELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAIS 228
E +S+++++ + ++L ++W I ++P M+ L+GWT PA S LV++VK S
Sbjct: 183 HEWVSQQIEDTSVNEVLNKNWPGLHIEPLQPPENMEVLIGWTGSPASSHHLVSEVKRLKS 242
Query: 229 E-----SFLIGSRTQVDALERAL----LAGEKFAIQSSMEKASQLLERLSPAIYTDRLKV 279
+ FL S V+ L A + G + I+++ E + + + I T LKV
Sbjct: 243 DPTFYGKFLERSHLCVEKLIHAFKTNHIKGVQQMIRTNREIIQSMDKEATIDIETAHLKV 302
Query: 280 LKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
L AE AK+SGAGGGDCGI + + K + Q W E ++ L
Sbjct: 303 LCSVAEKYGGAAKTSGAGGGDCGITIINSDVNKKLIYQEWLENEVKPL 350
>gi|70727399|ref|YP_254315.1| phosphomevalonate kinase [Staphylococcus haemolyticus JCSC1435]
gi|68448125|dbj|BAE05709.1| phosphomevalonate kinase [Staphylococcus haemolyticus JCSC1435]
Length = 358
Score = 136 bits (343), Expect = 2e-30, Method: Composition-based stats.
Identities = 98/350 (28%), Positives = 172/350 (49%), Gaps = 30/350 (8%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEP--- 62
+V+ GKLY+AGEYAV G +++ A+ ++T I+A+ +TS + + EP
Sbjct: 3 QVKAPGKLYVAGEYAVTEPGYKSVLIAVNRFVTASIEASN--AVTSTIHSKTLHYEPVTF 60
Query: 63 ----------DPDYA----LIQETIGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGI 107
D + A + I Y + +L+ F L+I ++ G K G+
Sbjct: 61 NRNEDKIDISDANAASQLKYVVTAIEVFEQYARSCNVKLKHFHLEIDSNLDDASGNKYGL 120
Query: 108 GSSGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRS 167
GSS +V++ +KA+ Y++ L ++KLA ++ S GD+A + + Y +
Sbjct: 121 GSSAAVLVSVVKALNEFYDMQLSNLYIYKLAVISNMRLQSLSSCGDIAVSVYSGWLAYST 180
Query: 168 FDRELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSA 226
FD + + ++M+E + ++L ++W I ++ M+ L+GWT PA S LV++VK
Sbjct: 181 FDHDWVKQQMEETSVNEVLEKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHLVSEVKRL 240
Query: 227 ISE-----SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERL----SPAIYTDRL 277
S+ FL S T V+ L A +Q + + +++++ + I T+ L
Sbjct: 241 KSDPSFYGRFLDQSHTCVENLIYAFKTNNIKGVQKMIRQNRMIIQQMDNEATVDIETENL 300
Query: 278 KVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
K+L + E AK+SGAGGGDCGIA+ + ++ W GI+ L
Sbjct: 301 KMLCDIGERYGAAAKTSGAGGGDCGIAIIDNRIDKNRIYNEWASHGIKPL 350
>gi|9937374|gb|AAG02432.1|AF290089_3 phosphomevalonate kinase [Staphylococcus haemolyticus]
Length = 358
Score = 136 bits (342), Expect = 2e-30, Method: Composition-based stats.
Identities = 98/350 (28%), Positives = 172/350 (49%), Gaps = 30/350 (8%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEP--- 62
+V+ GKLY+AGEYAV G +++ A+ ++T I+A+ +TS + + EP
Sbjct: 3 QVKAPGKLYVAGEYAVTEPGYKSVLIAVDRFVTASIEASN--AVTSTIHSKTLHYEPVTF 60
Query: 63 ----------DPDYA----LIQETIGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGI 107
D + A + I Y + +L+ F L+I ++ G K G+
Sbjct: 61 NRNEDKIDISDANAASQLKYVVTAIEVFEQYARSCNVKLKHFHLEIDSNLDDASGNKYGL 120
Query: 108 GSSGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRS 167
GSS +V++ +KA+ Y++ L ++KLA ++ S GD+A + + Y +
Sbjct: 121 GSSAAVLVSVVKALNEFYDMQLSNLYIYKLAVISNMRLQSLSSCGDIAVSVYSGWLAYST 180
Query: 168 FDRELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSA 226
FD + + ++M+E + ++L ++W I ++ M+ L+GWT PA S LV++VK
Sbjct: 181 FDHDWVKQQMEETSVNEVLEKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHLVSEVKRL 240
Query: 227 ISE-----SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERL----SPAIYTDRL 277
S+ FL S T V+ L A +Q + + +++++ + I T+ L
Sbjct: 241 KSDPSFYGRFLDQSHTCVENLIYAFKTDNIKGVQKMIRQNRMIIQQMDNEATVDIETENL 300
Query: 278 KVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
K+L + E AK+SGAGGGDCGIA+ + ++ W GI+ L
Sbjct: 301 KMLCDIGERYGAAAKTSGAGGGDCGIAIIDNRIDKNRIYNEWASHGIKPL 350
>gi|9937366|gb|AAG02426.1|AF290087_3 phosphomevalonate kinase [Staphylococcus aureus]
Length = 358
Score = 135 bits (341), Expect = 3e-30, Method: Composition-based stats.
Identities = 95/348 (27%), Positives = 167/348 (47%), Gaps = 26/348 (7%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLT--SDMFEHS-ASLEP 62
+V+ GKLY+AGEYAV G +++ A+ ++T I+ A Y+ T S H+ +
Sbjct: 3 QVKAPGKLYIAGEYAVTEPGYKSVLIALDRFVTATIEEATQYKGTIHSKALHHNPVTFSR 62
Query: 63 DPDYALIQE------------TIGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGIGS 109
D D +I + I Y + ++ F L I ++ G K G+GS
Sbjct: 63 DEDSIVISDPHAAKQLNYVVTAIEIFEQYAKSCDIAMKHFHLTIDSNLDDSNGHKYGLGS 122
Query: 110 SGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFD 169
S +V++ +K + Y++ L ++KLA +K S GD+A + + Y +FD
Sbjct: 123 SAAVLVSVIKVLNEFYDMKLSNLYIYKLAVIANMKLQSLSSCGDIAVSVYSGWLAYSTFD 182
Query: 170 RELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAIS 228
E + ++++ + ++L ++W I ++ M+ L+GWT PA S V++VK S
Sbjct: 183 HEWVKHQIEDTTVEEVLIKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHFVSEVKRLKS 242
Query: 229 E-----SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKV 279
+ FL S V+ L A +Q + + +++R+ I T++LK
Sbjct: 243 DPSFYGDFLEDSHRCVEKLIHAFKTNNIKGVQKMVRQNRTIIQRMDKEATVDIETEKLKY 302
Query: 280 LKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
L + AE + +K+SGAGGGDCGI + +++ W + GI+ L
Sbjct: 303 LCDIAEKYHGASKTSGAGGGDCGITIINKDVDKEKIYDEWTKHGIKPL 350
>gi|21282276|ref|NP_645364.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus MW2]
gi|49485458|ref|YP_042679.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus
MSSA476]
gi|21203713|dbj|BAB94412.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus MW2]
gi|49243901|emb|CAG42326.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus
MSSA476]
Length = 358
Score = 135 bits (340), Expect = 3e-30, Method: Composition-based stats.
Identities = 95/348 (27%), Positives = 167/348 (47%), Gaps = 26/348 (7%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLT--SDMFEHS-ASLEP 62
+V+ GKLY+AGEYAV G +++ A+ ++T I+ A Y+ T S H+ +
Sbjct: 3 QVKAPGKLYIAGEYAVTEPGYKSVLIALDRFVTATIEEADQYKGTIHSKALHHNPVTFSR 62
Query: 63 DPDYALIQE------------TIGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGIGS 109
D D +I + I Y + ++ F L I ++ G K G+GS
Sbjct: 63 DEDSIVISDPHAAKQLNYVVTAIEIFEQYAKSCDIAMKHFHLTIDSNLDDSNGHKYGLGS 122
Query: 110 SGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFD 169
S +V++ +K + Y++ L ++KLA +K S GD+A + + Y +FD
Sbjct: 123 SAAVLVSVIKVLNEFYDMKLSNLYIYKLAVIANMKLQSLSSCGDIAVSVYSGWLAYSTFD 182
Query: 170 RELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAIS 228
E + ++++ + ++L ++W I ++ M+ L+GWT PA S V++VK S
Sbjct: 183 HEWVKHQIEDTTVEEVLIKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHFVSEVKRLKS 242
Query: 229 E-----SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKV 279
+ FL S V+ L A +Q + + +++R+ I T++LK
Sbjct: 243 DPSFYGDFLEDSHHCVEKLIHAFKTNNIKGVQKMVRQNRTIIQRMDKEATVDIETEKLKY 302
Query: 280 LKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
L + AE + +K+SGAGGGDCGI + +++ W + GI+ L
Sbjct: 303 LCDIAEKYHGASKTSGAGGGDCGITIINKDVDKEKIYDEWTKHGIKPL 350
>gi|15923582|ref|NP_371116.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus Mu50]
gi|15926270|ref|NP_373803.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus N315]
gi|49482822|ref|YP_040046.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus
MRSA252]
gi|57650049|ref|YP_185523.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus COL]
gi|82750297|ref|YP_416038.1| phosphomevalonate kinase [Staphylococcus aureus RF122]
gi|88194353|ref|YP_499146.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus NCTC
8325]
gi|148267052|ref|YP_001245995.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus JH9]
gi|150393100|ref|YP_001315775.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus JH1]
gi|151220767|ref|YP_001331589.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus str.
Newman]
gi|156978921|ref|YP_001441180.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus Mu3]
gi|13700484|dbj|BAB41781.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus N315]
gi|14246360|dbj|BAB56754.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus Mu50]
gi|49240951|emb|CAG39618.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus
MRSA252]
gi|57284235|gb|AAW36329.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus COL]
gi|82655828|emb|CAI80230.1| phosphomevalonate kinase [Staphylococcus aureus RF122]
gi|87201911|gb|ABD29721.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus NCTC
8325]
gi|147740121|gb|ABQ48419.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus JH9]
gi|149945552|gb|ABR51488.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus JH1]
gi|150373567|dbj|BAF66827.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus str.
Newman]
gi|156721056|dbj|BAF77473.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus Mu3]
Length = 358
Score = 135 bits (340), Expect = 3e-30, Method: Composition-based stats.
Identities = 95/348 (27%), Positives = 167/348 (47%), Gaps = 26/348 (7%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLT--SDMFEHS-ASLEP 62
+V+ GKLY+AGEYAV G +++ A+ ++T I+ A Y+ T S H+ +
Sbjct: 3 QVKAPGKLYIAGEYAVTEPGYKSVLIALDRFVTATIEEADQYKGTIHSKALHHNPVTFSR 62
Query: 63 DPDYALIQE------------TIGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGIGS 109
D D +I + I Y + ++ F L I ++ G K G+GS
Sbjct: 63 DEDSIVISDPHAAKQLNYVVTAIEIFEQYAKSCDIAMKHFHLTIDSNLDDSNGHKYGLGS 122
Query: 110 SGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFD 169
S +V++ +K + Y++ L ++KLA +K S GD+A + + Y +FD
Sbjct: 123 SAAVLVSVIKVLNEFYDMKLSNLYIYKLAVIANMKLQSLSSCGDIAVSVYSGWLAYSTFD 182
Query: 170 RELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAIS 228
E + ++++ + ++L ++W I ++ M+ L+GWT PA S V++VK S
Sbjct: 183 HEWVKHQIEDTTVEEVLIKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHFVSEVKRLKS 242
Query: 229 E-----SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKV 279
+ FL S V+ L A +Q + + +++R+ I T++LK
Sbjct: 243 DPSFYGDFLEDSHRCVEKLIHAFKTNNIKGVQKMVRQNRTIIQRMDKEATVDIETEKLKY 302
Query: 280 LKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
L + AE + +K+SGAGGGDCGI + +++ W + GI+ L
Sbjct: 303 LCDIAEKYHGASKTSGAGGGDCGITIINKDVDKEKIYDEWTKHGIKPL 350
>gi|87160430|ref|YP_493277.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus
USA300]
gi|87126404|gb|ABD20918.1| phosphomevalonate kinase [Staphylococcus aureus subsp. aureus
USA300_FPR3757]
Length = 358
Score = 134 bits (336), Expect = 1e-29, Method: Composition-based stats.
Identities = 94/348 (27%), Positives = 166/348 (47%), Gaps = 26/348 (7%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLT--SDMFEHS-ASLEP 62
+V+ GKLY+AGEYAV G +++ A+ ++T I+ Y+ T S H+ +
Sbjct: 3 QVKAPGKLYIAGEYAVTEPGYKSVLIALDRFVTATIEETDQYKGTIHSKALHHNPVTFSR 62
Query: 63 DPDYALIQE------------TIGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGIGS 109
D D +I + I Y + ++ F L I ++ G K G+GS
Sbjct: 63 DEDSIVISDPHAAKQLNYVVTAIEIFEQYAKSCDIAMKHFHLTIDSNLDDSNGHKYGLGS 122
Query: 110 SGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFD 169
S +V++ +K + Y++ L ++KLA +K S GD+A + + Y +FD
Sbjct: 123 SAAVLVSVIKVLNEFYDMKLSNLYIYKLAVIANMKLQSLSSCGDIAVSVYSGWLAYSTFD 182
Query: 170 RELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAIS 228
E + ++++ + ++L ++W I ++ M+ L+GWT PA S V++VK S
Sbjct: 183 HEWVKHQIEDTTVEEVLIKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHFVSEVKRLKS 242
Query: 229 E-----SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKV 279
+ FL S V+ L A +Q + + +++R+ I T++LK
Sbjct: 243 DPSFYGDFLEDSHRCVEKLIHAFKTNNIKGVQKMVRQNRTIIQRMDKEATVDIETEKLKY 302
Query: 280 LKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
L + AE + +K+SGAGGGDCGI + +++ W + GI+ L
Sbjct: 303 LCDIAEKYHGASKTSGAGGGDCGITIINKDVDKEKIYDEWTKHGIKPL 350
>gi|27467281|ref|NP_763918.1| phosphomevalonate kinase [Staphylococcus epidermidis ATCC 12228]
gi|57866189|ref|YP_187836.1| phosphomevalonate kinase [Staphylococcus epidermidis RP62A]
gi|9937381|gb|AAG02437.1|AF290091_3 phosphomevalonate kinase [Staphylococcus epidermidis]
gi|27314824|gb|AAO03960.1|AE016745_59 phosphomevalonate kinase [Staphylococcus epidermidis ATCC 12228]
gi|57636847|gb|AAW53635.1| phosphomevalonate kinase [Staphylococcus epidermidis RP62A]
Length = 358
Score = 132 bits (331), Expect = 4e-29, Method: Composition-based stats.
Identities = 98/352 (27%), Positives = 165/352 (46%), Gaps = 34/352 (9%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDP- 64
+V+ GKLY+AGEYAV G +I+ A+ ++T I+A+ + HS +L +P
Sbjct: 3 QVKAPGKLYIAGEYAVTEPGYKSILIAVNRFVTATIEASNKVEGSI----HSKTLHYEPV 58
Query: 65 ------------------DYALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKL 105
+ I Y+ + L+ F L I + + G+K
Sbjct: 59 KFDRNEDRIEISDVQAAKQLKYVVTAIEVFEQYVRSCNMNLKHFHLTIDSNLADNSGQKY 118
Query: 106 GIGSSGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYY 165
G+GSS +V++ +KA+ Y L+L ++KLA +K S GD+A + + Y
Sbjct: 119 GLGSSAAVLVSVVKALNEFYGLELSNLYIYKLAVIANMKLQSLSSCGDIAVSVYSGWLAY 178
Query: 166 RSFDRELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVK 224
+FD + + ++M+E + +L ++W I ++ M+ L+GWT PA S LV++VK
Sbjct: 179 STFDHDWVKQQMEETSVNDVLEKNWPGLHIEPLQAPENMEVLIGWTGSPASSPHLVSEVK 238
Query: 225 SAISE-----SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERL----SPAIYTD 275
S+ FL S V++L +A +Q + ++++ + S I TD
Sbjct: 239 RLKSDPSFYGDFLDQSHACVESLIQAFKTNNIKGVQKMIRINRRIIQSMDNEASVEIETD 298
Query: 276 RLKVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
+LK L + E +K+SGAGGGDCGI + + WQ I+ L
Sbjct: 299 KLKKLCDVGEKHGGASKTSGAGGGDCGITIINKVIDKNIIYNEWQMNDIKPL 350
>gi|42519132|ref|NP_965062.1| mevalonate kinase [Lactobacillus johnsonii NCC 533]
gi|41583419|gb|AAS09028.1| mevalonate kinase [Lactobacillus johnsonii NCC 533]
Length = 357
Score = 130 bits (326), Expect = 2e-28, Method: Composition-based stats.
Identities = 98/346 (28%), Positives = 162/346 (46%), Gaps = 33/346 (9%)
Query: 8 QTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDP--- 64
Q GKLY+AGEYAVL PAI+ A+ ++ I + TS + HS D
Sbjct: 5 QAPGKLYIAGEYAVLEQNCPAILVAVNEFVRVSIAKSTG---TSGLI-HSKQYSQDSIHW 60
Query: 65 --------------DYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGS 109
+ I I + L + + L ++ ++ +GKK G+GS
Sbjct: 61 IRKGNQMVIDNRDNPFEYILSAINFTERFCLEQKVSMSLYDLHVNSDLDSADGKKYGLGS 120
Query: 110 SGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFD 169
S +V + T+KA+ Y L +L+FKL++ NGS GD+A + + Y++FD
Sbjct: 121 SAAVTVATVKAILNFYGLHCTKDLIFKLSAISHYSVQGNGSAGDIAASVYGGWLAYQTFD 180
Query: 170 RELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAIS 228
+ + K + L ++L E W KI+ + P ++ ++GW+++PA + LV++ +
Sbjct: 181 KAWLKKELATKSLSEVLNEAWPGLKIQLLTPPEGLNLVIGWSQKPASTSQLVDKTNAKKK 240
Query: 229 ------ESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLK 278
++FL SR V + + IQ + QLL+ + AI RL
Sbjct: 241 FIKTQYDTFLDESRKCVLDMIKGFNEKNISLIQKQIRLNRQLLKDFASLNHIAIEIPRLT 300
Query: 279 VLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGI 324
L AE N AK+SGAG GDCGI ++ + +++ W++ GI
Sbjct: 301 KLINIAEQFNGAAKTSGAGNGDCGIVIADEKTDIEEMKNNWRKNGI 346
>gi|116629676|ref|YP_814848.1| Phosphomevalonate kinase [Lactobacillus gasseri ATCC 33323]
gi|116095258|gb|ABJ60410.1| Phosphomevalonate kinase [Lactobacillus gasseri ATCC 33323]
Length = 380
Score = 128 bits (322), Expect = 4e-28, Method: Composition-based stats.
Identities = 99/346 (28%), Positives = 161/346 (46%), Gaps = 33/346 (9%)
Query: 8 QTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDP--- 64
Q GKLY+AGEYAVL PAI+ A+ ++ I + TS + HS D
Sbjct: 28 QAPGKLYIAGEYAVLEQNCPAILVAVNEFVRVSIAKSTG---TSGLI-HSKQYSQDSIHW 83
Query: 65 --------------DYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGS 109
+ I I + L + + L ++ ++ +GKK G+GS
Sbjct: 84 IRKGNQMVIDNRDNPFEYILSAIKFTERFCLEQKVPMSLYDLHVNSDLDSADGKKYGLGS 143
Query: 110 SGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFD 169
S +V + T+KA+ Y L +L+FKL++ NGS GD+A + + Y++FD
Sbjct: 144 SAAVTVATVKAILNFYGLHCTKDLIFKLSAISHYSVQGNGSAGDIAASVYGGWLAYQTFD 203
Query: 170 RELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAIS 228
+ + K + L ++L E W KI+ + P ++ ++GW+++PA + LV++ +
Sbjct: 204 KVWLKKELATKSLSEVLNEAWPGLKIQLLTPPEGLNLVIGWSQKPASTSQLVDKTNAKKK 263
Query: 229 ------ESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLK 278
++FL SR V + IQ + QLL+ + AI RL
Sbjct: 264 FIKTQYDTFLEQSRQCVLDMITGFNEKNIALIQKQIRLNRQLLKDFATLNHIAIEIPRLT 323
Query: 279 VLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGI 324
L AE N AK+SGAG GDCGI ++ + +++ W+E GI
Sbjct: 324 KLINIAEQFNGAAKTSGAGNGDCGIVIADEQTDIEEMKNIWRENGI 369
>gi|58337454|ref|YP_194039.1| phosphomevalonate kinase [Lactobacillus acidophilus NCFM]
gi|58254771|gb|AAV43008.1| phosphomevalonate kinase [Lactobacillus acidophilus NCFM]
Length = 360
Score = 127 bits (319), Expect = 1e-27, Method: Composition-based stats.
Identities = 94/343 (27%), Positives = 160/343 (46%), Gaps = 33/343 (9%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDP------ 64
GKLY+AGEYAVL PA++ A+ ++ I + TS HS D
Sbjct: 8 GKLYIAGEYAVLEQDCPAVLVAVNQFVRVSITKSN----TSTGLIHSKQYSQDSIHWVRQ 63
Query: 65 -----------DYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGS 112
+ I I Y + +++ + L ++ ++ +GKK G+GSS +
Sbjct: 64 GSKMVIDNRDNPFEYILSAISFTEQYCIEQNIKMKVYDLHVNSDLDSADGKKYGLGSSAA 123
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
V + T+KA+ Y + L EL++KL++ NGS GD+A + + Y++FD+
Sbjct: 124 VTVATVKAILHFYGVPLNNELIYKLSAISHYSVQGNGSAGDIAASVYGGWLAYQTFDKTW 183
Query: 173 ISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV---KSAIS 228
+ + + L ++ E W KI + P M ++GW+++PA + LV++ K+A++
Sbjct: 184 LKQELKSKTLSDVVNEAWPGLKIELLTPPKDMKLMIGWSQKPASTSRLVDETNANKAALN 243
Query: 229 ---ESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLK 281
++FL SR V + + I+ + ++L+ + AI RL L
Sbjct: 244 IEYKNFLAASRACVLKMIAGFESNNISIIKKQIRINRKILQHFAQINQIAIEIPRLTQLI 303
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGI 324
+ AE AK+SGAG GDCGI ++ L W+ GI
Sbjct: 304 KIAENFGGAAKTSGAGNGDCGIVITDSHTDVMALESEWRHNGI 346
>gi|116514013|ref|YP_812919.1| Phosphomevalonate kinase [Lactobacillus delbrueckii subsp.
bulgaricus ATCC BAA-365]
gi|116093328|gb|ABJ58481.1| Phosphomevalonate kinase [Lactobacillus delbrueckii subsp.
bulgaricus ATCC BAA-365]
Length = 360
Score = 121 bits (303), Expect = 7e-26, Method: Composition-based stats.
Identities = 95/334 (28%), Positives = 154/334 (46%), Gaps = 25/334 (7%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQ-AAPDYRLTSDMFEHSASLE-------- 61
GKLY+AGEYAVL PAI+ A+ Y+ I+ ++ D L S+
Sbjct: 8 GKLYIAGEYAVLEQDCPAILVALDQYVRVSIKPSSSDTGLIHSKQYSQDSIHWVRRGSKI 67
Query: 62 ----PDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSVVIL 116
D + I I Y L ++ + L ++ ++ +GKK G+GSS +V +
Sbjct: 68 VIDNRDNPFEYILSAISFTERYCLEQKVKMDVYDLFVNSDLDSADGKKYGLGSSAAVTVA 127
Query: 117 TLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKR 176
T+KA+ Y + +L++KL++ NGS GD+A + I Y++F++ + +
Sbjct: 128 TVKAILRFYGVQASKDLIYKLSTISHYSVQGNGSAGDIAASVYGGWIAYQTFNKLWLKEE 187
Query: 177 MDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISE------ 229
+ L ++ E W KI+ + P M+ L+GW++QPA + LV++ + +
Sbjct: 188 LASKSLSAVVGEAWPGLKIQPLVPPKGMELLIGWSQQPASTSRLVDKTNANKNNLRTEYA 247
Query: 230 SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLKEAAE 285
FL SR V + R IQ + +LL+ + AI RL L E A
Sbjct: 248 KFLADSRKCVLQMIRGFEEANIALIQKQIGINRRLLQHFAAINNIAIEIPRLTELIEIAN 307
Query: 286 GLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAW 319
AK+SGAG GDCGI + +L + W
Sbjct: 308 KFGGAAKTSGAGNGDCGIVIVNKDTDIDRLRKEW 341
>gi|9695272|dbj|BAB07792.1| phosphomevalonate kinase [Streptomyces sp. CL190]
Length = 374
Score = 120 bits (302), Expect = 9e-26, Method: Composition-based stats.
Identities = 105/350 (30%), Positives = 171/350 (48%), Gaps = 37/350 (10%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYR------LTSDMFEHSAS----- 59
GKL++AGEYAV+ G PAI+ A+ +++ + A ++SD+ +
Sbjct: 14 GKLFVAGEYAVVDPGNPAILVAVDRHISVTVSDADADTGAADVVISSDLGPQAVGWRWHD 73
Query: 60 ---LEPDPD--------YALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIG 108
+ DPD A + I ++ L G ++ +L +S ++ +G+K G+G
Sbjct: 74 GRLVVRDPDDGQQARSALAHVVSAIETVGRLLGERGQKVPALTLSVSSRLHEDGRKFGLG 133
Query: 109 SSGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSF 168
SSG+V + T+ A+AA L+L + F+LA + GS GDLA + I Y++
Sbjct: 134 SSGAVTVATVAAVAAFCGLELSTDERFRLAMLATAELDPKGSGGDLAASTWGGWIAYQAP 193
Query: 169 DRELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVK--- 224
DR + V + + L W +R + + VGWT +PA + LV+ +
Sbjct: 194 DRAFVLDLARRVGVDRTLKAPWPGHSVRRLPAPKGLTLEVGWTGEPASTASLVSDLHRRT 253
Query: 225 ---SAISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRL 277
SA + F+ + V + AL +G+ ++ + +A Q L RL I+T +L
Sbjct: 254 WRGSASHQRFVETTTDCVRSAVTALESGDDTSLLHEIRRARQELARLDDEVGLGIFTPKL 313
Query: 278 KVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLI---QAWQEAGI 324
L +AAE + AK SGAGGGDCGIAL DA +S+ + Q W+ AG+
Sbjct: 314 TALCDAAEAVGGAAKPSGAGGGDCGIAL-LDAEASRDITHVRQRWETAGV 362
>gi|104773997|ref|YP_618977.1| Phosphomevalonate kinase [Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842]
gi|103423078|emb|CAI97799.1| Phosphomevalonate kinase [Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842]
Length = 360
Score = 120 bits (301), Expect = 1e-25, Method: Composition-based stats.
Identities = 95/334 (28%), Positives = 154/334 (46%), Gaps = 25/334 (7%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQ-AAPDYRLTSDMFEHSASLE-------- 61
GKLY+AGEYAVL PAI+ A+ Y+ I+ ++ D L S+
Sbjct: 8 GKLYIAGEYAVLEQDCPAILVALDQYVRVSIKPSSSDTGLIHSKQYSQDSIHWVRRGSKI 67
Query: 62 ----PDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSVVIL 116
D + I I Y L ++ + L ++ ++ +GKK G+GSS +V +
Sbjct: 68 VIDNRDNPFEYILSAISFTERYCLEQKVKMDVYDLFVNSDLDSADGKKYGLGSSAAVTVA 127
Query: 117 TLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKR 176
T+KA+ Y + +L++KL++ NGS GD+A + I Y++F++ + +
Sbjct: 128 TVKAILRFYGVQASKDLIYKLSTISHYSVQGNGSAGDIAASVYGGWIAYQTFNKLWLKEE 187
Query: 177 MDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISE------ 229
+ L ++ E W KI+ + P M+ L+GW++QPA + LV++ + +
Sbjct: 188 LASKSLSAVVGEAWPGLKIQQLVPPKDMELLIGWSQQPASTSRLVDKTNANKNNLRTEYA 247
Query: 230 SFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLKEAAE 285
FL SR V + R IQ + +LL+ + AI RL L E A
Sbjct: 248 KFLADSRKCVLQMIRGFEEANIALIQKQIGINRRLLQHFAAINNIAIEIPRLTELIEIAN 307
Query: 286 GLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAW 319
AK+SGAG GDCGI + +L + W
Sbjct: 308 KFGGAAKTSGAGNGDCGIVIVNKDTDIDRLRKEW 341
>gi|57753872|dbj|BAD86802.1| phosphomevalonate kinase [Streptomyces sp. KO-3988]
Length = 375
Score = 119 bits (298), Expect = 3e-25, Method: Composition-based stats.
Identities = 102/350 (29%), Positives = 161/350 (46%), Gaps = 37/350 (10%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAI--PIYMTGEIQAAPDYRLTSDMFEHSASL-------- 60
GKL++AGEYAV+ G PA++ A+ I + + A D ++SD+ + +
Sbjct: 13 GKLFVAGEYAVVEPGTPAVLVAVDREITVMATLSDAADIVISSDLVPRAVTWRWRDGRLH 72
Query: 61 -------EPDPD-----YALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIG 108
+ D D A + + ++ L+ G L + IS ++ G+K G+G
Sbjct: 73 APGTKNGDADGDGARGALAHVVSAVETVRRLLVERGLPLPGLEISISSRLHDNGRKYGLG 132
Query: 109 SSGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSF 168
SSG+V + T+ A+ +L LDL + ++LA GS GDLA + I Y++
Sbjct: 133 SSGAVTVATIDALTSLCGLDLSLDARYRLAVISSAGIDPKGSGGDLAASTWGGWIAYQAP 192
Query: 169 DRELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVK--- 224
DR + + + L W +R + + VGWT PA + LV+ +
Sbjct: 193 DRAFVLDLTRRHGIEEALRTPWPGLAVRRLPAPRGLTLEVGWTGSPASTTSLVSGLHRRT 252
Query: 225 ---SAISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLL----ERLSPAIYTDRL 277
+A +FL S V A AL AG+ ++ + +A Q L + + I+T L
Sbjct: 253 WRGTASHRAFLETSTDFVRASITALEAGDDQSLLRQIRRARQELACLDDEVGLGIFTPEL 312
Query: 278 KVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLI---QAWQEAGI 324
L AE + AK SGAGGGDCGIAL DA ++ + Q W AG+
Sbjct: 313 TALCAVAETVGGAAKPSGAGGGDCGIAL-LDAEATHDISHVRQGWAAAGV 361
>gi|40882373|dbj|BAD07377.1| phosphomevalonate kinase [Actinoplanes sp. A40644]
Length = 371
Score = 115 bits (288), Expect = 4e-24, Method: Composition-based stats.
Identities = 108/350 (30%), Positives = 164/350 (46%), Gaps = 32/350 (9%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAI--PIYMTGEIQAAPDYRLTSDMFEHSASLE-- 61
R GKL++AGEYAV+ G PAI+ A+ + +T D + SD+ LE
Sbjct: 8 RSDAPGKLFVAGEYAVMEPGHPAILIAVDRQVSVTVSTPDGGDVVIDSDLNPAETRLERR 67
Query: 62 ------------PDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIG 108
+PD + IG + L G ++ L I ++ R+G K G+G
Sbjct: 68 GGDLVVAGADAGQEPDGLGHVLSAIGVVGELLAERGSRMPAMHLSIRSRLHRDGTKFGLG 127
Query: 109 SSGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSF 168
SSG+V + + A+A+ ++L PE ++LA + S GDLA + + Y +
Sbjct: 128 SSGAVTVAVVTAVASYCGVELSPEQRYRLAMLATARHDAASSGGDLAASVWGGWLAYHAP 187
Query: 169 DRELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV---- 223
DR ++ + ++L W F +R ++P + VGWT QPA + L ++
Sbjct: 188 DRAVVLDLAGRRGVGEMLCSPWPGFSVRRLEPPRGLALEVGWTGQPASTFSLAQRLGSGR 247
Query: 224 --KSAISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRL 277
SA FL S V A AL G+ + + A ++L L I+T RL
Sbjct: 248 WRGSAAQRGFLARSDECVRAAIGALDRGDDRELLEHIRAARRVLAGLDDEVRLGIFTPRL 307
Query: 278 KVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSK---QLIQAWQEAGI 324
L +AA+ + AK SGAGGGDCGIAL DAA+ + QL + W AG+
Sbjct: 308 TALCDAADAVGGAAKPSGAGGGDCGIAL-LDAAAKRDISQLRKEWVAAGV 356
>gi|16799091|ref|NP_469359.1| hypothetical protein lin0012 [Listeria innocua Clip11262]
gi|16412433|emb|CAC95245.1| lin0012 [Listeria innocua]
Length = 360
Score = 114 bits (286), Expect = 6e-24, Method: Composition-based stats.
Identities = 103/346 (29%), Positives = 176/346 (50%), Gaps = 20/346 (5%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSAS- 59
MK +V+ GKLY+AGEYAV+ +G AI+ A+ Y+T ++ + L +E+ S
Sbjct: 5 MKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWIPHYENPVSW 64
Query: 60 -----LEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSGS 112
L+PD + + E I T+L + G +L P + I ++ ++ G K G+GSS +
Sbjct: 65 PIGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMVIETELIDQSGAKYGLGSSAA 124
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
+ + A+ + ++ FKLA+ L NGS GD+A + I Y +FD+E
Sbjct: 125 ATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEW 184
Query: 173 ISKRMDEVDLPQLLAEDWD-FKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ R+ L + E W +I +++ + F VGWT P + LV+Q+ + E
Sbjct: 185 VKHRLAYKSLEWFMKEPWPMLQIETLEEPVPT-FSVGWTGTPVSTGKLVSQIHAFKQEDS 243
Query: 231 -----FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKVLK 281
FL + + + +A ++ + SS+++ ++L+ L I T LK L
Sbjct: 244 KNYQHFLTRNNEIMKQIIQAFHTKDEELLYSSIKENRRILQELGTKAGVNIETSLLKELA 303
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
++AE + KSSG+GGGDCGIA S +++L+ W++ GI+ L
Sbjct: 304 DSAENMGGAGKSSGSGGGDCGIAFSKTKELAEKLVNEWEKLGIKHL 349
>gi|153164835|ref|ZP_01926010.1| phosphomevalonate kinase [Listeria monocytogenes FSL N1-017]
gi|153200399|ref|ZP_01942561.1| phosphomevalonate kinase [Listeria monocytogenes HPB2262]
gi|133728535|gb|EBA30233.1| phosphomevalonate kinase [Listeria monocytogenes FSL N1-017]
gi|133736677|gb|EBA38375.1| phosphomevalonate kinase [Listeria monocytogenes HPB2262]
Length = 359
Score = 114 bits (286), Expect = 7e-24, Method: Composition-based stats.
Identities = 103/346 (29%), Positives = 176/346 (50%), Gaps = 20/346 (5%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSAS- 59
MK +V+ GKLY+AGEYAV+ +G AI+ A+ Y+T ++ + L +E+ S
Sbjct: 4 MKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWIPHYENPVSW 63
Query: 60 -----LEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSGS 112
L+PD + + E I T+L + G +L P + I ++ ++ G K G+GSS +
Sbjct: 64 PIGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMVIETELIDQSGAKYGLGSSAA 123
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
+ + A+ + ++ FKLA+ L NGS GD+A + I Y +FD+E
Sbjct: 124 ATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEW 183
Query: 173 ISKRMDEVDLPQLLAEDWD-FKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ R+ L + E W +I +++ + F VGWT P + LV+Q+ + E
Sbjct: 184 VKHRLAYKSLEWFMKEPWPMLQIETLEEPVPT-FSVGWTGTPVSTGKLVSQIHAFKQEDS 242
Query: 231 -----FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKVLK 281
FL + + + +A ++ + SS+++ ++L+ L I T LK L
Sbjct: 243 KNYQHFLTRNNEIMKQIIQAFHTKDEELLYSSIKENRRILQELGTKAGVNIETSLLKELA 302
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
++AE + KSSG+GGGDCGIA S +++L+ W++ GI+ L
Sbjct: 303 DSAENMGGAGKSSGSGGGDCGIAFSKTKELAEKLVNEWEKLGIKHL 348
>gi|46906237|ref|YP_012626.1| phosphomevalonate kinase [Listeria monocytogenes str. 4b F2365]
gi|46879501|gb|AAT02803.1| phosphomevalonate kinase [Listeria monocytogenes str. 4b F2365]
Length = 356
Score = 114 bits (286), Expect = 7e-24, Method: Composition-based stats.
Identities = 103/346 (29%), Positives = 176/346 (50%), Gaps = 20/346 (5%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSAS- 59
MK +V+ GKLY+AGEYAV+ +G AI+ A+ Y+T ++ + L +E+ S
Sbjct: 1 MKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWIPHYENPVSW 60
Query: 60 -----LEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSGS 112
L+PD + + E I T+L + G +L P + I ++ ++ G K G+GSS +
Sbjct: 61 PIGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMVIETELIDQSGAKYGLGSSAA 120
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
+ + A+ + ++ FKLA+ L NGS GD+A + I Y +FD+E
Sbjct: 121 ATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEW 180
Query: 173 ISKRMDEVDLPQLLAEDWD-FKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ R+ L + E W +I +++ + F VGWT P + LV+Q+ + E
Sbjct: 181 VKHRLAYKSLEWFMKEPWPMLQIETLEEPVPT-FSVGWTGTPVSTGKLVSQIHAFKQEDS 239
Query: 231 -----FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKVLK 281
FL + + + +A ++ + SS+++ ++L+ L I T LK L
Sbjct: 240 KNYQHFLTRNNEIMKQIIQAFHTKDEELLYSSIKENRRILQELGTKAGVNIETSLLKELA 299
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
++AE + KSSG+GGGDCGIA S +++L+ W++ GI+ L
Sbjct: 300 DSAENMGGAGKSSGSGGGDCGIAFSKTKELAEKLVNEWEKLGIKHL 345
>gi|16802060|ref|NP_463545.1| hypothetical protein lmo0012 [Listeria monocytogenes EGD-e]
gi|153176175|ref|ZP_01931434.1| phosphomevalonate kinase [Listeria monocytogenes FSL N3-165]
gi|153181043|ref|ZP_01934010.1| phosphomevalonate kinase [Listeria monocytogenes F6900]
gi|153184365|ref|ZP_01935124.1| phosphomevalonate kinase [Listeria monocytogenes J0161]
gi|153192653|ref|ZP_01939613.1| phosphomevalonate kinase [Listeria monocytogenes J2818]
gi|16409371|emb|CAC98227.1| lmo0012 [Listeria monocytogenes]
gi|126942868|gb|EBA20602.1| phosphomevalonate kinase [Listeria monocytogenes J0161]
gi|127763690|gb|EBA24524.1| phosphomevalonate kinase [Listeria monocytogenes J2818]
gi|133728888|gb|EBA30586.1| phosphomevalonate kinase [Listeria monocytogenes FSL N3-165]
gi|133731561|gb|EBA33259.1| phosphomevalonate kinase [Listeria monocytogenes F6900]
Length = 359
Score = 113 bits (283), Expect = 2e-23, Method: Composition-based stats.
Identities = 102/346 (29%), Positives = 176/346 (50%), Gaps = 20/346 (5%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSAS- 59
MK +V+ GKLY+AGEYAV+ +G AI+ A+ Y+T ++ + L +E+ S
Sbjct: 4 MKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWIPHYENPVSW 63
Query: 60 -----LEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSGS 112
L+PD + + E I T+L + G +L P + I ++ ++ G K G+GSS +
Sbjct: 64 PVGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMIIETELIDQSGAKYGLGSSAA 123
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
+ + A+ + ++ FKLA+ L NGS GD+A + I Y +FD+E
Sbjct: 124 ATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEW 183
Query: 173 ISKRMDEVDLPQLLAEDWD-FKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ R+ L + E W +I +++ + F VGWT P + LV+Q+ + E
Sbjct: 184 VKHRLAYKSLEWFMKEPWPMLQIETLEEPVPT-FSVGWTGTPVSTGKLVSQIHAFKQEDS 242
Query: 231 -----FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKVLK 281
FL + + + +A ++ + S++++ ++L+ L I T LK L
Sbjct: 243 KNYQHFLTRNNEIMKQIIQAFHTKDEELLYSAIKENRRILQELGTKAGVNIETSLLKELA 302
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
++AE + KSSG+GGGDCGIA S +++L+ W++ GI+ L
Sbjct: 303 DSAENMGGAGKSSGSGGGDCGIAFSKTKELAEKLVNEWEKLGIKHL 348
>gi|47097295|ref|ZP_00234853.1| phosphomevalonate kinase [Listeria monocytogenes str. 1/2a F6854]
gi|47014340|gb|EAL05315.1| phosphomevalonate kinase [Listeria monocytogenes str. 1/2a F6854]
Length = 356
Score = 113 bits (282), Expect = 2e-23, Method: Composition-based stats.
Identities = 102/346 (29%), Positives = 176/346 (50%), Gaps = 20/346 (5%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSAS- 59
MK +V+ GKLY+AGEYAV+ +G AI+ A+ Y+T ++ + L +E+ S
Sbjct: 1 MKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWIPHYENPVSW 60
Query: 60 -----LEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSGS 112
L+PD + + E I T+L + G +L P + I ++ ++ G K G+GSS +
Sbjct: 61 PVGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMIIETELIDQSGAKYGLGSSAA 120
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
+ + A+ + ++ FKLA+ L NGS GD+A + I Y +FD+E
Sbjct: 121 ATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEW 180
Query: 173 ISKRMDEVDLPQLLAEDWD-FKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ R+ L + E W +I +++ + F VGWT P + LV+Q+ + E
Sbjct: 181 VKHRLAYKSLEWFMKEPWPMLQIETLEEPVPT-FSVGWTGTPVSTGKLVSQIHAFKQEDS 239
Query: 231 -----FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKVLK 281
FL + + + +A ++ + S++++ ++L+ L I T LK L
Sbjct: 240 KNYQHFLTRNNEIMKQIIQAFHTKDEELLYSAIKENRRILQELGTKAGVNIETSLLKELA 299
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
++AE + KSSG+GGGDCGIA S +++L+ W++ GI+ L
Sbjct: 300 DSAENMGGAGKSSGSGGGDCGIAFSKTKELAEKLVNEWEKLGIKHL 345
>gi|116871435|ref|YP_848216.1| phosphomevalonate kinase [Listeria welshimeri serovar 6b str.
SLCC5334]
gi|116740313|emb|CAK19431.1| unnamed protein product [Listeria welshimeri serovar 6b str.
SLCC5334]
Length = 360
Score = 113 bits (282), Expect = 2e-23, Method: Composition-based stats.
Identities = 103/346 (29%), Positives = 174/346 (50%), Gaps = 20/346 (5%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSAS- 59
MK +V+ GKLY+AGEYAV+ +G AI+ A+ Y+T ++ + L +E+ S
Sbjct: 5 MKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSDRNELWIPHYENPVSW 64
Query: 60 -----LEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSGS 112
L+PD + + E I T+L + G +L P + I ++ ++ G K G+GSS +
Sbjct: 65 PVGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMVIETELIDQSGAKYGLGSSAA 124
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
+ + A+ + ++ FKLA+ L NGS GD+A + I Y +FD+E
Sbjct: 125 ATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEW 184
Query: 173 ISKRMDEVDLPQLLAEDWD-FKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ R+ L + E W +I +++ + F VGWT P + LV+Q+ + E
Sbjct: 185 VKHRLAYKSLEWFMKEPWPMLQIETLEEPVPT-FSVGWTGTPVSTGKLVSQIHAFKQEDS 243
Query: 231 -----FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKVLK 281
FL + + + +A ++ + SS+++ ++L+ L I T LK L
Sbjct: 244 KNYQHFLTRNNEIMKQIIQAFHTKDEELLYSSIKENRRILQELGTKAGVNIETSLLKELA 303
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
++AE KSSG+GGGDCGIA S +++L+ W+ GI+ L
Sbjct: 304 DSAENFGGAGKSSGSGGGDCGIAFSKTKELAEKLVNEWETLGIKHL 349
>gi|153197979|ref|ZP_01942149.1| phosphomevalonate kinase [Listeria monocytogenes 10403S]
gi|127632315|gb|EBA21997.1| phosphomevalonate kinase [Listeria monocytogenes 10403S]
Length = 359
Score = 110 bits (276), Expect = 1e-22, Method: Composition-based stats.
Identities = 101/346 (29%), Positives = 175/346 (50%), Gaps = 20/346 (5%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSAS- 59
MK +V+ GKLY+AGEYAV+ +G AI+ A+ Y+T ++ + L +E+ S
Sbjct: 4 MKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWIPHYENPVSW 63
Query: 60 -----LEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSGS 112
L+PD + + E I T+L + G +L P + I ++ ++ G K G+GSS +
Sbjct: 64 PVGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMIIETELIDQSGAKYGLGSSAA 123
Query: 113 VVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDREL 172
+ + A+ + ++ FKLA+ L NGS GD+A + I Y +FD+E
Sbjct: 124 ATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEW 183
Query: 173 ISKRMDEVDLPQLLAEDWD-FKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES- 230
+ R+ L + E W +I +++ + F VGWT P + LV+Q+ + E
Sbjct: 184 VKHRLAYKSLEWFMKEPWPMLQIETLEEPVPT-FSVGWTGTPVSTGKLVSQIHAFKQEDS 242
Query: 231 -----FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPA----IYTDRLKVLK 281
FL + + + +A ++ + ++++ ++L+ L I T LK L
Sbjct: 243 KNYQHFLTRNNEIMKQIIQAFHTKDEELLYLAIKENRRILQELGTKAGVNIETSLLKELA 302
Query: 282 EAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
++AE + KSSG+GGGDCGIA S +++L+ W++ GI+ L
Sbjct: 303 DSAENMGGAGKSSGSGGGDCGIAFSKTKELAEKLVNEWEKLGIKHL 348
>gi|9711348|dbj|BAB07819.1| phosphomevalonate kinase [Kitasatospora griseola]
Length = 360
Score = 109 bits (272), Expect = 3e-22, Method: Composition-based stats.
Identities = 100/337 (29%), Positives = 151/337 (44%), Gaps = 26/337 (7%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQ--AAPDYRLTSDMFE-------HSASLE 61
GKL++AGEYAV+ G AI+ A+ Y+T + AAP ++SD+ L
Sbjct: 13 GKLFVAGEYAVVEPGNRAILVAVDRYVTVTVSDGAAPGVVVSSDIGAGPVHHPWQDGRLT 72
Query: 62 PDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKAM 121
+ + ++ L G + P IS + +G+K G+GSSG+V + T+ A+
Sbjct: 73 GGTGTPHVVAAVETVARLLAERGRSVPPLGWSISSTLHEDGRKFGLGSSGAVTVATVSAV 132
Query: 122 AALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVD 181
AA L+L E F+ A + GS GD+A + I YR+ DR+ +
Sbjct: 133 AAHCGLELTAEERFRTALIASARIDPRGSGGDIATSTWGGWIAYRAPDRDAVLDLTRRQG 192
Query: 182 LPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVK------SAISESFLIG 234
+ + L W F +R + P + VGWT P + L+ + S ++
Sbjct: 193 VDEALRAPWPGFSVR-LSPPRNLCLEVGWTGNPVSTTSLLTDLHRRTWRGSPAYRRYVGA 251
Query: 235 SRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLKEAAEGLNCV 290
+ VDA AL G+ + + +A + RL I+T L L AE
Sbjct: 252 TGELVDAAVIALEDGDTEGLLRQVRRARHEMVRLDDEVGLGIFTPELTALCAIAERAG-A 310
Query: 291 AKSSGAGGGDCGIALSFDAAS---SKQLIQAWQEAGI 324
AK SGAGGGDCGIAL DA + L + W AG+
Sbjct: 311 AKPSGAGGGDCGIAL-LDAEARYDRSPLHRQWAAAGV 346
>gi|15212072|emb|CAC51372.1| phosphomevalonate kinase [Lactobacillus helveticus]
Length = 294
Score = 107 bits (268), Expect = 8e-22, Method: Composition-based stats.
Identities = 75/274 (27%), Positives = 132/274 (48%), Gaps = 12/274 (4%)
Query: 63 DPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKMER-EGKKLGIGSSGSVVILTLKAM 121
D + I I Y + +++ + L ++ ++ +GKK G+GSS +V + T+KA+
Sbjct: 7 DNPFEYILSAISYTEQYCIEQNIKMKVYDLHVNSDLDSADGKKYGLGSSAAVTVATVKAI 66
Query: 122 AALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVD 181
Y + + EL++KL++ NGS GD+A + + Y++FD++ + +
Sbjct: 67 LHFYGVKMSNELVYKLSAISHYSVQGNGSAGDIAASVYGGWLAYQTFDKKWLQYELANKT 126
Query: 182 LPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV---KSAIS---ESFLIG 234
L ++ E W KI + P M ++GW+++PA + LV++ K+A++ ++FL
Sbjct: 127 LSDVVNEAWPGLKIELLTPPHDMKLMIGWSQKPASTSRLVDETNANKAALNTEYKNFLAA 186
Query: 235 SRTQVDALERALLAGEKFAIQSSMEKASQLLERLSP----AIYTDRLKVLKEAAEGLNCV 290
S V + A I+ + LL+ + AI RL L + AE
Sbjct: 187 SSECVLKMIVGFKAKNIALIKKQIRVNRHLLQHFAKINQIAIEIPRLTQLIKIAEDFGGA 246
Query: 291 AKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGI 324
AK+SGAG GDCGI ++ L W+ GI
Sbjct: 247 AKTSGAGNGDCGIVITDADTDVDALENEWRRNGI 280
>gi|54024178|ref|YP_118420.1| putative phosphomevalonate kinase [Nocardia farcinica IFM 10152]
gi|54015686|dbj|BAD57056.1| putative phosphomevalonate kinase [Nocardia farcinica IFM 10152]
Length = 368
Score = 106 bits (265), Expect = 2e-21, Method: Composition-based stats.
Identities = 101/361 (27%), Positives = 162/361 (44%), Gaps = 32/361 (8%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPD------------------YRLTSD 52
GKL++AGEYAV+ G+ AI+ A+ Y T ++A+ R +
Sbjct: 8 GKLFVAGEYAVVEPGRHAILTAVDRYATATVRASHTDAAVTVCTDLGQGVQLACRRAGTG 67
Query: 53 MFEHSASLEPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSG 111
+ + P + A + + L+ G+ + P + ++ + +R G+K G+G+S
Sbjct: 68 LVPANGRARPRAELAYVFAAAAVVERLLIERGHPVLPCRVAVTADLADRSGRKFGLGASA 127
Query: 112 SVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRE 171
+V T+ A+ + L L ++LA L S GD+A + + Y S DR
Sbjct: 128 AVTAATVAALGRFHRLGLSRMDRYRLAMLATLSVDPAASGGDVAASTWGGWLVYGSPDRR 187
Query: 172 LISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAIS-- 228
+S+ + + +LL+ W + + P VGWT P + LV V+
Sbjct: 188 WVSETLATRSVTELLSRPWPGLSVHRLPPPARSALRVGWTGTPVATPGLVRSVRRGRDRR 247
Query: 229 ----ESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLS----PAIYTDRLKVL 280
+F+ + V AL RAL A E A+ + + +A +LL L I T RL+ L
Sbjct: 248 AGDYRAFVAATEECVRALARALEADEPGAVHAGILRARELLVHLDSVARAGIMTPRLRAL 307
Query: 281 KEAAEGLNCVAKSSGAGGGDCGIAL--SFDAASSKQLIQAWQEAGIELLYRERMGRDEPE 338
A + + AK SGAGGGDCGIA D A+ +L W+ AGIE L R E +
Sbjct: 308 CAAGDAVGAAAKPSGAGGGDCGIAFLDPADTAALAELADRWRAAGIEPLTVRPHPRQEAD 367
Query: 339 S 339
+
Sbjct: 368 T 368
>gi|23097682|ref|NP_691148.1| phosphomevalonate kinase [Oceanobacillus iheyensis HTE831]
gi|22775905|dbj|BAC12183.1| phosphomevalonate kinase [Oceanobacillus iheyensis HTE831]
Length = 369
Score = 105 bits (263), Expect = 4e-21, Method: Composition-based stats.
Identities = 97/354 (27%), Positives = 164/354 (46%), Gaps = 31/354 (8%)
Query: 2 KASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMF------- 54
K V+ GKL +AGE+AVL Q + A+ Y+ I A +Y L+ + F
Sbjct: 3 KRQLTVKVPGKLMIAGEFAVLEPYQKLAVMAVNRYVYATITDAENYTLSLEDFGLHDIAW 62
Query: 55 ---EHSASLEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKME-REGKKLGIGS 109
+ ++E D + ++ +++ I TYL + F L +++ G K G+GS
Sbjct: 63 SYQTGTVNIESDDERFSFVKDAIYITCTYLEEKSIGIPSFHLSTRSELDDASGVKYGLGS 122
Query: 110 SG----SVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYY 165
S SVV L+ +A Y E++F+LA+ + NGS D+A + Y
Sbjct: 123 SAAIVTSVVSAILRFVAPRYA---TKEIIFRLAALSHVCTQGNGSGADIAASTYGGFRQY 179
Query: 166 RSFDRE-LISKRMDEVDLPQLLAEDWDF-KIRSIKPCLAMDFLVGWTKQPAISKDLVNQV 223
SF + L++ + + +++ +W + + +I+ ++ VGWT A +K+LV Q+
Sbjct: 180 SSFQADWLLNTYKNASTISEVVDMEWKYYQSENIRIPDFLNVCVGWTGTAASTKNLVQQI 239
Query: 224 K------SAISESFLIGSRTQV----DALERALLAGEKFAIQSSMEKASQLLERLSPAIY 273
+ S E FL S+ V D + L+ ++ + + + + ++ I
Sbjct: 240 RLLKVSDSDAYEHFLQSSKEAVGLFLDGMNSENLSMLMDGVRKNRQALAHVGQKAKTPIE 299
Query: 274 TDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
T L L + AE L K SGAGGGDCGIA + ++ L AW E GI+ L
Sbjct: 300 TSMLTKLCDLAEQLGGAGKPSGAGGGDCGIAFMYSKDQAENLFHAWAEVGIKPL 353
>gi|153799375|gb|ABS50446.1| NapT4 [Streptomyces aculeolatus]
Length = 412
Score = 102 bits (254), Expect = 3e-20, Method: Composition-based stats.
Identities = 82/246 (33%), Positives = 116/246 (47%), Gaps = 13/246 (5%)
Query: 92 LKISGKMEREGKKLGIGSSGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSM 151
++I + G+K G+GSSG+V + + A+AA LDL F+LA + GS
Sbjct: 153 VRIESNLHDNGRKYGLGSSGAVTVAAVAAVAAFCGLDLPAGDRFRLAMLATARIDPKGSG 212
Query: 152 GDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWT 210
GDLA + I Y++ DR+ + Q L W F +R + P +DF VGWT
Sbjct: 213 GDLAASTWGGWISYQAPDRDFVVDLARRRGTAQALRTPWPHFAVRPLPPPAGLDFQVGWT 272
Query: 211 KQPAISKDLVNQV------KSAISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQL 264
PA + LV + S +F+ S V A+ AL G+ + + +A
Sbjct: 273 GSPASTASLVASLHRRTWRHSPSHRAFVATSTGIVHAVADALDKGDGPGLLHQIRRARSE 332
Query: 265 LERLSP----AIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIAL--SFDAASSKQLIQA 318
L RL I+T L L +AAE + AK SGAGGGDCGIAL + +L Q
Sbjct: 333 LARLDDEVGLGIFTTELTALCDAAEAVGGAAKPSGAGGGDCGIALLPAHAPHDISRLRQR 392
Query: 319 WQEAGI 324
W AG+
Sbjct: 393 WAAAGV 398
>gi|86475802|dbj|BAE78979.1| phosphomevalonate kinase [Streptomyces sp. KO-3988]
Length = 379
Score = 90.5 bits (223), Expect = 1e-16, Method: Composition-based stats.
Identities = 104/354 (29%), Positives = 159/354 (44%), Gaps = 41/354 (11%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMT----GEIQAA------PDYRLTSDM------- 53
GKL++ GEYAV+ G PA++ A+ Y+T G ++ P ++SD+
Sbjct: 13 GKLFVVGEYAVVEPGNPAVLVAVDRYVTVTVTGPVEPGVAAGVEPGVEISSDLGPRGERR 72
Query: 54 -------FEHSASLEPDPDYAL--IQETIGSMNTYLLALGYQLQPFSLKISGKMEREGKK 104
+ A PD L + I ++ L G FSL + + G K
Sbjct: 73 RWRDGRLVPYDAHDGPDARAGLAHVLSAIETVARLLAERGLPAPEFSLSVVSGLHDGGTK 132
Query: 105 LGIGSSGSVVILTLKAMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIY 164
G+GSS +V + T+ A+AA L E F+LA + GS GDLA + I
Sbjct: 133 YGLGSSAAVTVATVAAVAAFCGLTPTDEERFRLALLATAEIDPKGSGGDLAAGVWGGWIA 192
Query: 165 YRSFDRELISKRMDEVDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV 223
YR+ DR + + L W F +R + P + VGWT PA + L++ +
Sbjct: 193 YRAPDRAAVLALARAHGVEAALRAPWPGFAVRRLPPPAGLALEVGWTGDPASTTALLSDL 252
Query: 224 K------SAISESFLIGSRTQVDALERALLAGEKFAIQSSMEKASQLL----ERLSPAIY 273
+A F+ + A AL G+ + + +A + L E ++ ++
Sbjct: 253 HRRPCRGTAAHRRFVSTTTDCASAAIAALEGGDGRRLLDQIRRARRELALLDEEVALGVF 312
Query: 274 TDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSK---QLIQAWQEAGI 324
T RL L EAAE + AK SGAGGGDCGIAL DA + + +L + W+ AG+
Sbjct: 313 TPRLTALCEAAEAVGGAAKPSGAGGGDCGIAL-LDAGAPQDIARLRERWESAGV 365
>gi|124520336|ref|ZP_01695503.1| phosphomevalonate kinase [Bacillus coagulans 36D1]
gi|124497674|gb|EAY45228.1| phosphomevalonate kinase [Bacillus coagulans 36D1]
Length = 366
Score = 89.7 bits (221), Expect = 2e-16, Method: Composition-based stats.
Identities = 75/291 (25%), Positives = 139/291 (47%), Gaps = 22/291 (7%)
Query: 6 RVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPD--YRLTSDMFEHSASL--- 60
+V+ GKL +AGEYAV+ G PA++ A+ Y+T E++ + + + L H+A
Sbjct: 7 QVKAPGKLMIAGEYAVIEPGCPAVVAAVDRYITIEVKESTENLFSLPQIGIPHAAWRVEN 66
Query: 61 ------EPDPDYALIQETIGSMNTYLLALGYQLQPFSLKISGKME--REGKKLGIGSSGS 112
D IQ + L+ L+P + ++ +++ G+K G+GSS +
Sbjct: 67 GEVRFDHDDSKLRFIQNALAVFYRLLMEKSIPLRPLHITVTSELDDPATGQKYGLGSSAA 126
Query: 113 VVILTLKAMAALYE-LDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRE 171
++ L A+ ++ + E +FKLA+ LK NGS DLA + ++ Y +F +
Sbjct: 127 ILSAVLAALLHAHQGMPDTKEAIFKLAAVAHLKTQGNGSGADLAASVYGGMLKYAAFRPD 186
Query: 172 LISKRMDE-VDLPQLLAEDW-DFKIRSIKPCLAMDFLVGWTKQPAISKDLVNQV---KSA 226
I R++ + +LLAE W I ++ + F GWT + + +V ++ + A
Sbjct: 187 WIFSRLEAGCTISELLAETWPHLAISKLELPPGLIFCTGWTGKAVATGPMVERIGKLREA 246
Query: 227 ISES---FLIGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPAIYT 274
+E+ FL S VD L + + + + S+ + + L++L A +T
Sbjct: 247 ATETYTAFLQESTAAVDKLAESFMQQDAAGVFESIRQNRRALQKLEAAAHT 297
>gi|116618482|ref|YP_818853.1| Phosphomevalonate kinase [Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293]
gi|116097329|gb|ABJ62480.1| Phosphomevalonate kinase [Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293]
Length = 339
Score = 85.9 bits (211), Expect = 4e-15, Method: Composition-based stats.
Identities = 88/332 (26%), Positives = 147/332 (44%), Gaps = 23/332 (6%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYR-LTSDMFEHSASL-------EP 62
GKL+LAGEYA+ G A++ AI + EI A + +TS++ + E
Sbjct: 8 GKLFLAGEYAITNPGNTALVVAITTGLAIEITTAREVSTITSNIITDDLTFNINQETPEQ 67
Query: 63 DPDYALIQETIGSMNTYLLA--LGYQLQPFSLKISGKMEREGKKLGIGSSGSVVILTLKA 120
D+ ++ + M Y+ + LQ ++ I M K+G+GSS +VV+ + A
Sbjct: 68 TDDWRFVRAAVNLMTHYVHTKKIRATLQEVNIDIKSNMNHPTGKIGLGSSAAVVVGIVSA 127
Query: 121 MAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEV 180
++L+L FK+A+ L NGS+GD+A I + I Y+S D
Sbjct: 128 FNNHFKLNLTLLTQFKIAALAHLHVQKNGSLGDVAAITYGGAISYQSPDLSQYQTADKNW 187
Query: 181 DLPQLLAEDWDFKIRSIKPCLAMDF--LVGWTKQPA-ISKDLVNQVKSAISESFLIGSRT 237
P+++ W K+ + D+ L+G T + A SK L ++ + SF S+
Sbjct: 188 LQPEIVDVPWK-KLNIVPLSWPQDWQILLGATHESADTSKALASK---TLPTSFFKESQH 243
Query: 238 QVDALERALLAGEKFAIQSSMEKASQLLER-LSPAIYTDRLKVLKEAAEGLNCVAKSSGA 296
D + ++++ + ++ +L LS T +L +L + + K SGA
Sbjct: 244 VADDVVQSVIKNDYKQFSKGLKLNQTILRHTLSQKYVTPKLAILLQTLG--DTAGKISGA 301
Query: 297 GGGDCGIALSFDAASSKQLIQAWQEAGIELLY 328
G GD G A+ L + W AGIE Y
Sbjct: 302 GFGDNGFAV---VNGPTDLPEMWLAAGIEPHY 330
>gi|118618816|ref|YP_907148.1| phosphomevalonate kinase [Mycobacterium ulcerans Agy99]
gi|118570926|gb|ABL05677.1| phosphomevalonate kinase [Mycobacterium ulcerans Agy99]
Length = 370
Score = 85.1 bits (209), Expect = 6e-15, Method: Composition-based stats.
Identities = 104/347 (29%), Positives = 155/347 (44%), Gaps = 37/347 (10%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAP-----DYRLTSDMFEHSASLEPDPD 65
GKL + GE+AV+ G A++ A+ Y+T +QAA ++S++ + L+ D
Sbjct: 9 GKLVILGEFAVVEPGCGALVAAMDRYVT--VQAADLGIGGGVAVSSELIAGTVDLDSDRS 66
Query: 66 YALIQ-ETIGSMNTYLLALGYQL-----QPFSLKISGKMEREGKKLGIGSSGSVVILTLK 119
A Q I S +A+ Q + L I+ ++ G KLG+GSSG+V + +
Sbjct: 67 VAARQLPHIASA----VAIARQWLDCPDRGVGLTITSQLHERGVKLGLGSSGAVTVAVVD 122
Query: 120 AMAALYELDLKPELLFKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDE 179
A+ A + + LF+LA + +GS D+A F + YRS DR+ I + +
Sbjct: 123 AVTAAWGAPVDRTTLFRLALIATARLTTSGSGVDVAAAVFGGWLSYRSPDRQAIVE-LAA 181
Query: 180 VDLPQLLAEDWDFKIRSIKPCLAMDFLVGWTKQPAISKDLV------NQVKSAISESFLI 233
DL L+ +W + + LVGWT PA + ++ + I F
Sbjct: 182 ADLHSLVHAEWPGHVIAAVAPPPERLLVGWTGGPAAITAQIGRPASGDRTRDEIVRRFRE 241
Query: 234 GSRTQVDAL------ERALLAGEKFAIQSSMEKASQL------LERLSP-AIYTDRLKVL 280
S VDA A G A E Q L+R + I+T+RL L
Sbjct: 242 SSEECVDAAIGLLTPATASCCGSAPAGAGLGEHVRQFRNLLCELDRATAMGIFTERLNAL 301
Query: 281 KEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
AAE AK SGAGGGDCGIAL+ + L ++W AGI L
Sbjct: 302 CAAAETSGAAAKPSGAGGGDCGIALAGSSVDVAGLGRSWLHAGIRPL 348
>gi|116491122|ref|YP_810666.1| Phosphomevalonate kinase [Oenococcus oeni PSU-1]
gi|116091847|gb|ABJ57001.1| Phosphomevalonate kinase [Oenococcus oeni PSU-1]
Length = 249
Score = 75.1 bits (183), Expect = 6e-12, Method: Composition-based stats.
Identities = 78/250 (31%), Positives = 116/250 (46%), Gaps = 41/250 (16%)
Query: 81 LALGYQLQPF-SLKISGKMEREGKKLGIGSSGSVVILTLKAMAALYELDLKPELLFKLAS 139
LAL + + F S S + +G K G+GSSG+ +L M + L + +F+ A
Sbjct: 24 LALVFSIDRFISKNYSQLVNEKGVKYGLGSSGAYAVL----MTKMENSSLSDKDIFRQAL 79
Query: 140 YVLLKRGDNGSMGDLACIAFEDLIYYR--SFDRELISKRMDEVDLPQLLAEDWDFKIRSI 197
+ + S D+A + L+ Y+ SF + E+W+
Sbjct: 80 ILSRQTQPQNSGADIAASTYSGLLLYKNGSFPERI------------FFPENWNL----- 122
Query: 198 KPCLAMDFLVGWTKQPAISKDLV--NQVKSA-ISESFLIGSRTQVDALERALLAGEKFAI 254
+VGWT +PAI+ +LV NQ+ S + ES +I R VD ++ EKF
Sbjct: 123 --------IVGWTGKPAITSELVKKNQLSSFFVKESDMI-VRKMVDFIKAKDF--EKF-- 169
Query: 255 QSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGIALSFDAASSKQ 314
+ A + LE+LS + TD+L E A+ AK SGAGGGD IA + D S+Q
Sbjct: 170 NQEIFLAEKNLEKLS-GVLTDKLAKAIEIAKNFGIEAKISGAGGGDNVIAFTRDPKISQQ 228
Query: 315 LIQAWQEAGI 324
+ WQEAGI
Sbjct: 229 IKNNWQEAGI 238
>gi|47093022|ref|ZP_00230801.1| phosphomevalonate kinase [Listeria monocytogenes str. 4b H7858]
gi|47018590|gb|EAL09344.1| phosphomevalonate kinase [Listeria monocytogenes str. 4b H7858]
Length = 150
Score = 63.5 bits (153), Expect = 2e-08, Method: Composition-based stats.
Identities = 40/129 (31%), Positives = 69/129 (53%), Gaps = 8/129 (6%)
Query: 1 MKASARVQTCGKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSAS- 59
MK +V+ GKLY+AGEYAV+ +G AI+ A+ Y+T ++ + L +E+ S
Sbjct: 1 MKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWIPHYENPVSW 60
Query: 60 -----LEPDPD-YALIQETIGSMNTYLLALGYQLQPFSLKISGKM-EREGKKLGIGSSGS 112
L+PD + + E I T+L + G +L P + I ++ ++ G K G+GSS +
Sbjct: 61 PIGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMVIETELIDQSGAKYGLGSSAA 120
Query: 113 VVILTLKAM 121
+ + A+
Sbjct: 121 ATVAVINAL 129
>gi|47093023|ref|ZP_00230802.1| phosphomevalonate kinase [Listeria monocytogenes str. 4b H7858]
gi|47018591|gb|EAL09345.1| phosphomevalonate kinase [Listeria monocytogenes str. 4b H7858]
Length = 218
Score = 61.6 bits (148), Expect = 7e-08, Method: Composition-based stats.
Identities = 63/204 (30%), Positives = 104/204 (50%), Gaps = 12/204 (5%)
Query: 135 FKLASYVLLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRMDEVDLPQLLAEDWD-FK 193
FKLA+ L NGS GD+A + I Y +FD+E + R+ L + E W +
Sbjct: 5 FKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEWVKHRLAYKSLEWFMKEPWPMLQ 64
Query: 194 IRSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISES------FLIGSRTQVDALERALL 247
I +++ + F VGWT P + LV+Q+ + E FL + + + +A
Sbjct: 65 IETLEEPVPT-FSVGWTGTPVSTGKLVSQIHAFKQEDSKNYQHFLTRNNEIMKQIIQAFH 123
Query: 248 AGEKFAIQSSMEKASQLLERLSPA----IYTDRLKVLKEAAEGLNCVAKSSGAGGGDCGI 303
++ + SS+++ ++L+ L I T LK L ++AE + KSSG+GGGDCGI
Sbjct: 124 TKDEELLYSSIKENRRILQELGTKAGVNIETSLLKELADSAENMGGAGKSSGSGGGDCGI 183
Query: 304 ALSFDAASSKQLIQAWQEAGIELL 327
A S +++L+ W++ GI+ L
Sbjct: 184 AFSKTKELAEKLVNEWEKLGIKHL 207
>gi|108763233|ref|YP_633172.1| putative phosphomevalonate kinase [Myxococcus xanthus DK 1622]
gi|108467113|gb|ABF92298.1| putative phosphomevalonate kinase [Myxococcus xanthus DK 1622]
Length = 359
Score = 54.7 bits (130), Expect = 9e-06, Method: Composition-based stats.
Identities = 90/335 (26%), Positives = 149/335 (44%), Gaps = 28/335 (8%)
Query: 11 GKLYLAGEYAVLTAGQPAIIKAIPIYMTGEIQAAPDYRLTSDMFEHSASLEPDP------ 64
GKL+L+GEYAVL G A + A+ ++ D R+ + E + + P
Sbjct: 9 GKLFLSGEYAVLWGGV-ARLAAVAPRTAAYVRRRADARVHVCLEEGTLAGSTTPLGVRWE 67
Query: 65 -----DYALIQETIGSMNTYLLALGYQLQPFSLKIS-GKMEREGKKLGIGSSGSVVILTL 118
+A + +++ L A G Q F L ++ + G+KLG+G GS L
Sbjct: 68 REVPAGFAFVAR---ALDEALRAHGRASQGFDLAVAPSAVGPNGQKLGMG--GSACATVL 122
Query: 119 KAMAALYELDLKPELLFKLASYV-LLKRGDNGSMGDLACIAFEDLIYYRSFDRELISKRM 177
A A Y L+ + + L KLA +G GS GD+A ++ YR +D + +
Sbjct: 123 AAEGARYVLEERYDAL-KLALLAHTQGQGGKGSGGDVATSFAGGVLRYRRYDVAPLIEAS 181
Query: 178 DEVDLPQLLAEDWDFKI-RSIKPCLAMDFLVGWTKQPAISKDLVNQVKSAISE----SFL 232
+ L LAE + R P ++M + +T + A ++ L+ QV++ + E SF+
Sbjct: 182 NTGRLRAALAESPSVDVWRLPSPRVSMAY--AFTGESASTRVLIGQVEARLEEAGRRSFV 239
Query: 233 IGSRTQVDALERALLAGEKFAIQSSMEKASQLLERLSPAIYTDRLKVLKEAAEGLNCVAK 292
S T A+E L G+ A +++ LL L P + T+ ++ + A K
Sbjct: 240 ERSDTLGHAIEDGLSGGDFRAFSEAVKAQHALLLELGP-LETEGMRRVLALAATYGAAGK 298
Query: 293 SSGAGGGDCGIALSFDAASSKQLIQAWQEAGIELL 327
SGAGGGD I + DA ++ + + G L
Sbjct: 299 LSGAGGGDGCILFAPDAQVRAEMCKGLEARGFHTL 333
Database: nr
Posted date: Sep 17, 2007 11:41 AM
Number of letters in database: 999,999,834
Number of sequences in database: 2,976,859
Database: /nucleus1/users/jsaw/ncbi/db/nr.01
Posted date: Sep 17, 2007 11:48 AM
Number of letters in database: 894,087,890
Number of sequences in database: 2,493,262
Lambda K H
0.318 0.134 0.377
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,159,415,093
Number of Sequences: 5470121
Number of extensions: 46276096
Number of successful extensions: 131319
Number of sequences better than 1.0e-05: 88
Number of HSP's better than 0.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 131106
Number of HSP's gapped (non-prelim): 90
length of query: 339
length of database: 1,894,087,724
effective HSP length: 133
effective length of query: 206
effective length of database: 1,166,561,631
effective search space: 240311695986
effective search space used: 240311695986
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 130 (54.7 bits)