BLASTX+BEAUTY Search Results

WU-BLAST 2.0 search of the National Center for Biotechnology Information's NR Protein Database.

BEAUTY post-processing provided by the Human Genome Sequencing Center, Baylor College of Medicine.

BEAUTY Reference:
Worley KC, Culpepper P, Wiese BA, Smith RF. BEAUTY-X: enhanced BLAST searches for DNA queries. Bioinformatics 1998;14(10):890-1. Abstract

Worley KC, Wiese BA, Smith RF. BEAUTY: an enhanced BLAST-based search tool that integrates multiple biological information resources into sequence similarity search results. Genome Res 1995 Sep;5(2):173-84 Abstract



RepeatMasker repeats found in sequence:

No Repeats Found.

Reference:  Gish, Warren (1994-1997).  unpublished.
Gish, Warren and David J. States (1993).  Identification of protein coding
regions by database similarity search.  Nat. Genet. 3:266-72.

Notice: statistical significance is estimated under the assumption that the equivalent of one entire reading frame in the query sequence codes for protein and that significant alignments will involve only coding reading frames.

Query= 'D13E05_I05_09.ab1' (292 letters)

  Translating both strands of query sequence in all 6 reading frames

Database: nr 625,274 sequences; 197,782,623 total letters.



     Observed Numbers of Database Sequences Satisfying
    Various EXPECTation Thresholds (E parameter values)

        Histogram units:      = 10 Sequences     : less than 10 sequences

 EXPECTation Threshold
 (E parameter)
    |
    V   Observed Counts-->
  10000 2416 588 |==========================================================
   6310 1828 523 |====================================================
   3980 1305 488 |================================================
   2510  817 285 |============================
   1580  532 174 |=================
   1000  358 117 |===========
    631  241  68 |======
    398  173  31 |===
    251  142  32 |===
    158  110  36 |===
    100   74  32 |===
   63.1   42  12 |=
   39.8   30   4 |:
   25.1   26   8 |:
   15.8   18   2 |:
 >>>>>>>>>>>>>>>>>>>>>  Expect = 10.0, Observed = 16  <<<<<<<<<<<<<<<<<
   10.0   16   1 |:
   6.31   15   1 |:
   3.98   14   0 |
   2.51   14   0 |
   1.58   14   0 |
   1.00   14   1 |:
   0.63   13   0 |
   0.40   13   0 |
   0.25   13   1 |:
   0.16   12   1 |:
   0.10   11   0 |
  0.063   11   0 |
  0.040   11   0 |
  0.025   11   1 |:


                                                                     Smallest
                                                                       Sum
                                                     Reading  High  Probability
Sequences producing High-scoring Segment Pairs:        Frame Score  P(N)      N
gi|31291|emb|CAA36016.1|(X51728) fumarylacetoacetase ... +1   113  4.6e-05   1
gi|3157928|gb|AAC17611.1|(AC002131) Similar to fumary... +1   114  4.7e-05   1
gi|4557587ref|NP_000128.1| fumarylacetoacetase [Homo ... +1   113  6.3e-05   1
gi|12739036ref|XP_007704.2| fumarylacetoacetase [Homo... +1   113  6.7e-05   1
gi|8569274|pdb|1QCO|AChain A, Crystal Structure Of Fu... +1   110  0.00014   1
gi|6753814ref|NP_034306.1| fumarylacetoacetate hydrol... +1   109  0.00017   1
gi|8393349ref|NP_058877.1| fumarylacetoacetate hydrol... +1   109  0.00017   1
gi|544273|sp|P35505|FAAA_MOUSEFUMARYLACETOACETASE (FU... +1   109  0.00017   1
gi|253320|gb|AAB22822.1|fumarylacetoacetate hydrolase... +1   109  0.00017   1
gi|8569272|pdb|1QCN|AChain A, Crystal Structure Of Fu... +1   109  0.00017   1
gi|7292429|gb|AAF47833.1|(AE003480) CG14993 gene prod... +1    89  0.019     1
gi|7505698|pir||T25813hypothetical protein K10C2.4 - ... +1    83  0.10      1
gi|12313291|emb|CAC24418.1|(AL512978) Hypothetical [S... +3    82  0.17      1
gi|11348567|pir||E83394fumarylacetoacetase PA2008 [im... +1    76  0.48      1
gi|110562|pir||S25462Ig kappa chain V region - mouse ... +3    62  0.98      1
gi|197274|gb|AAA38993.1|(M31268) IgK chain [Mus muscu... +3    64  0.9995    1

Use the and icons to retrieve links to Entrez:

E = Retrieve Entrez links (e.g., Medline abstracts, FASTA-formatted sequence reports).
R = Retrieve links to Related sequences (neighbors).
Use the icon (if present) to retrieve links to the Sequence Retrieval System (SRS).
Use the icon (if present) to retrieve links to the Ligand Enzyme and Chemical Compound Database .
Use the icon (if present) to retrieve links to the Protein Data Bank database.


to_Entrezto_Relatedto_Related >gi|31291|emb|CAA36016.1|  (X51728) fumarylacetoacetase (AA 1-349) [Homo
            sapiens]
            Length = 349

Frame  1 hits (HSPs):                                                _____
                        __________________________________________________
Database sequence:     |                     |                    |       | 349
                       0                   150                  300

  Plus Strand HSPs:

 Score = 113 (39.8 bits), Expect = 4.6e-05, P = 4.6e-05
 Identities = 17/26 (65%), Positives = 24/26 (92%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             VI+TGYC+G+GY +GFG C+GK++PA
Sbjct:   320 VIITGYCQGDGYRIGFGQCAGKVLPA 345


to_Entrezto_Relatedto_Related >gi|3157928|gb|AAC17611.1|  (AC002131) Similar to fumarylacetoacetate hydrolase,
            gb|L41670 from Emericella nidulans. [Arabidopsis thaliana]
            Length = 408

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                  |                 |             | 408
                       0                150               300

  Plus Strand HSPs:

 Score = 114 (40.1 bits), Expect = 4.7e-05, P = 4.7e-05
 Identities = 19/28 (67%), Positives = 24/28 (85%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPAAP 84
             V  +G CKG+GY+VGFGTC+GKIVP+ P
Sbjct:   381 VTFSGVCKGDGYNVGFGTCTGKIVPSPP 408


to_Entrezto_Related >gi|4557587  ref|NP_000128.1| fumarylacetoacetase [Homo sapiens]
            >gi|119778|sp|P16930|FAAA_HUMAN FUMARYLACETOACETASE
            (FUMARYLACETOACETATE HYDROLASE) (BETA-DIKETONASE) (FAA)
            >gi|106043|pir||A37926 fumarylacetoacetase (EC 3.7.1.2) - human
            >gi|182393|gb|AAA52422.1| (M55150) fumarylacetoacetate hydrolase
            [Homo sapiens]
            Length = 419

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                 |                 |              | 419
                       0               150               300

  Plus Strand HSPs:

 Score = 113 (39.8 bits), Expect = 6.3e-05, P = 6.3e-05
 Identities = 17/26 (65%), Positives = 24/26 (92%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             VI+TGYC+G+GY +GFG C+GK++PA
Sbjct:   390 VIITGYCQGDGYRIGFGQCAGKVLPA 415


to_Entrezto_Related >gi|12739036  ref|XP_007704.2| fumarylacetoacetase [Homo sapiens]
            Length = 437

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                 |                |               | 437
                       0               150              300

  Plus Strand HSPs:

 Score = 113 (39.8 bits), Expect = 6.7e-05, P = 6.7e-05
 Identities = 17/26 (65%), Positives = 24/26 (92%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             VI+TGYC+G+GY +GFG C+GK++PA
Sbjct:   408 VIITGYCQGDGYRIGFGQCAGKVLPA 433


to_Entrezto_Related >gi|8569274|pdb|1QCO|A  Chain A, Crystal Structure Of Fumarylacetoacetate
            Hydrolase Complexed With Fumarate And Acetoacetate
            >gi|8569275|pdb|1QCO|B Chain B, Crystal Structure Of
            Fumarylacetoacetate Hydrolase Complexed With Fumarate And
            Acetoacetate
            Length = 423

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                 |                 |              | 423
                       0               150               300

  Plus Strand HSPs:

 Score = 110 (38.7 bits), Expect = 0.00014, P = 0.00014
 Identities = 19/31 (61%), Positives = 27/31 (87%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA-AP*G 90
             VI+TG+C+G+GY VGFG C+GK++PA +P G
Sbjct:   392 VIITGHCQGDGYRVGFGQCAGKVLPALSPAG 422


to_Entrezto_Related >gi|6753814  ref|NP_034306.1| fumarylacetoacetate hydrolase [Mus musculus]
            >gi|1083328|pir||A56825 fumarylacetoacetase (EC 3.7.1.2) - mouse
            >gi|50973|emb|CAA77819.1| (Z11774) fumarylacetoacetase [Mus
            musculus]
            Length = 419

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                 |                 |              | 419
                       0               150               300

  Plus Strand HSPs:

 Score = 109 (38.4 bits), Expect = 0.00017, P = 0.00017
 Identities = 17/26 (65%), Positives = 24/26 (92%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             VI+TG+C+G+GY VGFG C+GK++PA
Sbjct:   390 VIITGHCQGDGYRVGFGQCAGKVLPA 415


to_Entrezto_Related >gi|8393349  ref|NP_058877.1| fumarylacetoacetate hydrolase [Rattus norvegicus]
            >gi|119779|sp|P25093|FAAA_RAT FUMARYLACETOACETASE
            (FUMARYLACETOACETATE HYDROLASE) (BETA-DIKETONASE) (FAA)
            >gi|92242|pir||JH0467 fumarylacetoacetase (EC 3.7.1.2) - rat
            >gi|204090|gb|AAA41142.1| (M77694) fumarylacetoacetate hydrolase
            [Rattus norvegicus]
            Length = 419

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                 |                 |              | 419
                       0               150               300

  Plus Strand HSPs:

 Score = 109 (38.4 bits), Expect = 0.00017, P = 0.00017
 Identities = 17/26 (65%), Positives = 24/26 (92%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             VI+TG+C+G+GY VGFG C+GK++PA
Sbjct:   390 VIITGHCQGDGYRVGFGQCAGKVLPA 415


to_Entrezto_Relatedto_Relatedto_ec >gi|544273|sp|P35505|FAAA_MOUSE  FUMARYLACETOACETASE (FUMARYLACETOACETATE
            HYDROLASE) (BETA-DIKETONASE) (FAA) >gi|284750|pir||A40219
            fumarylacetoacetate hydrolase - mouse >gi|8569283|pdb|1QQJ|A Chain
            A, Crystal Structure Of Mouse Fumarylacetoacetate Hydrolase Refined
            At 1.55 Angstrom Resolution >gi|8569284|pdb|1QQJ|B Chain B, Crystal
            Structure Of Mouse Fumarylacetoacetate Hydrolase Refined At 1.55
            Angstrom Resolution >gi|193222|gb|AAA37591.1| (M84145)
            fumarylacetoacetate hydrolase [Mus musculus]
            Length = 419

Frame  1 hits (HSPs):                                                 ____
Annotated Domains:      __________________________________________________
                        __________________________________________________
Database sequence:     |                 |                 |              | 419
                       0               150               300
__________________

Annotated Domains:
   PFAM                 FAA_hydrolase: Fumarylacetoacetate (FAA) 145..359
   PRODOM               PD009659: FAAA(3) Q94272(1) O65374(1)    1..162
   PRODOM               PD002459: FAAA(3) HPCE(2) Q46978(2)      164..263
   PRODOM               PD009658: FAAA(3) Q94272(1) O65374(1)    266..414
   PROSITE              BZIP_BASIC: bZIP transcription factors b 82..97
__________________


  Plus Strand HSPs:

 Score = 109 (38.4 bits), Expect = 0.00017, P = 0.00017
 Identities = 17/26 (65%), Positives = 24/26 (92%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             VI+TG+C+G+GY VGFG C+GK++PA
Sbjct:   390 VIITGHCQGDGYRVGFGQCAGKVLPA 415


to_Entrezto_Related >gi|253320|gb|AAB22822.1|  fumarylacetoacetate hydrolase, FAH [mice, Peptide,
            419 aa]
            Length = 419

Frame  1 hits (HSPs):                                                 ____
Annotated Domains:               ___                                      
                        __________________________________________________
Database sequence:     |                 |                 |              | 419
                       0               150               300
__________________

Annotated Domains:
   PROSITE              BZIP_BASIC: bZIP transcription factors b 82..97
__________________


  Plus Strand HSPs:

 Score = 109 (38.4 bits), Expect = 0.00017, P = 0.00017
 Identities = 17/26 (65%), Positives = 24/26 (92%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             VI+TG+C+G+GY VGFG C+GK++PA
Sbjct:   390 VIITGHCQGDGYRVGFGQCAGKVLPA 415


to_Entrezto_Related >gi|8569272|pdb|1QCN|A  Chain A, Crystal Structure Of Fumarylacetoacetate
            Hydrolase >gi|8569273|pdb|1QCN|B Chain B, Crystal Structure Of
            Fumarylacetoacetate Hydrolase
            Length = 421

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                 |                 |              | 421
                       0               150               300

  Plus Strand HSPs:

 Score = 109 (38.4 bits), Expect = 0.00017, P = 0.00017
 Identities = 17/26 (65%), Positives = 24/26 (92%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             VI+TG+C+G+GY VGFG C+GK++PA
Sbjct:   392 VIITGHCQGDGYRVGFGQCAGKVLPA 417


to_Entrezto_Relatedto_Related >gi|7292429|gb|AAF47833.1|  (AE003480) CG14993 gene product [Drosophila
            melanogaster]
            Length = 349

Frame  1 hits (HSPs):                                                _____
                        __________________________________________________
Database sequence:     |                     |                    |       | 349
                       0                   150                  300

  Plus Strand HSPs:

 Score = 89 (31.3 bits), Expect = 0.019, P = 0.019
 Identities = 14/28 (50%), Positives = 21/28 (75%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPAAP 84
             VI+ G+C+ NG  +GFG C G+++PA P
Sbjct:   319 VIIRGHCEKNGLRIGFGECVGQVLPAHP 346


to_Entrezto_Relatedto_Related >gi|7505698|pir||T25813  hypothetical protein K10C2.4 - Caenorhabditis elegans
            >gi|1515342|gb|AAB06900.1| (U39852) coded for by C. elegans cDNA
            yk83g11.5; coded for by C. elegans cDNA yk59b11.5; coded for by C.
            elegans cDNA yk101c4.5; coded for by C. elegans cDNA yk108e2.5;
            coded for by C. elegans cDNA cm15b10; coded for by C. elegans cDNA
            yk62c7.5; coded >
            Length = 418

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                 |                 |              | 418
                       0               150               300

  Plus Strand HSPs:

 Score = 83 (29.2 bits), Expect = 0.11, P = 0.10
 Identities = 14/26 (53%), Positives = 19/26 (73%), Frame = +1

Query:     1 VILTGYCKGNGYSVGFGTCSGKIVPA 78
             V L+G C+ NG  +GFG C GK++PA
Sbjct:   391 VNLSGVCEKNGVRIGFGECRGKVLPA 416


to_Entrezto_Relatedto_Related >gi|12313291|emb|CAC24418.1|  (AL512978) Hypothetical [Sulfolobus solfataricus]
            Length = 512

Frame  3 hits (HSPs):                                _______              
                        __________________________________________________
Database sequence:     |              |              |             |      | 512
                       0            150            300           450

  Plus Strand HSPs:

 Score = 82 (28.9 bits), Expect = 0.18, P = 0.17
 Identities = 22/69 (31%), Positives = 33/69 (47%), Frame = +3

Query:    18 LQGKWLLCWVWYLLRQDCTRSSMRLVSFHSLFQLWWEELYNQEPACLIYSAHNMTLIKLV 197
             L G   LC + Y    + T S+    +  S  QLW + L N  P  + YS ++ +     
Sbjct:   307 LSGYVPLCMIVYTY--NLTNSNSGFYTVGSYSQLWIKPLDNNSPVYITYSGYSYS----- 359

Query:   198 FYEYYTFSF 224
             +YEYY F+F
Sbjct:   360 YYEYYNFTF 368


to_Entrezto_Relatedto_Related >gi|11348567|pir||E83394  fumarylacetoacetase PA2008 [imported] - Pseudomonas
            aeruginosa (strain PAO1) >gi|9948011|gb|AAG05396.1|AE004627_4
            (AE004627) fumarylacetoacetase [Pseudomonas aeruginosa]
            Length = 432

Frame  1 hits (HSPs):                                                 ____
                        __________________________________________________
Database sequence:     |                 |                |               | 432
                       0               150              300

  Plus Strand HSPs:

 Score = 76 (26.8 bits), Expect = 0.65, P = 0.48
 Identities = 15/29 (51%), Positives = 19/29 (65%), Frame = +1

Query:     1 VILTGYCKGNGY-SVGFGTCSGKIVPAAP 84
             VIL   CK  G+ S+GFG C GK++ A P
Sbjct:   400 VILRARCKREGHVSIGFGECRGKVLAALP 428


to_Entrezto_Relatedto_Related >gi|110562|pir||S25462  Ig kappa chain V region - mouse
            >gi|938263|emb|CAA47881.1| (X67623) IgG light chain V region [Mus
            musculus]
            Length = 91

Frame  3 hits (HSPs):          _________________________                  
                        __________________________________________________
Database sequence:     |          |          |          |          |      | 91
                       0         20         40         60         80

  Plus Strand HSPs:

 Score = 62 (21.8 bits), Expect = 4.0, P = 0.98
 Identities = 16/44 (36%), Positives = 24/44 (54%), Frame = +3

Query:    57 LRQDCT---RSSMRLVSFHSLFQLWWEELYNQEPACLIYSAHNM 179
             LRQ  T   R+S  + S+ + F  W+++   Q P  LIY A N+
Sbjct:    15 LRQRATISCRASESVDSYGNSFMHWYQQKPGQPPKLLIYHASNL 58


to_Entrezto_Relatedto_Related >gi|197274|gb|AAA38993.1|  (M31268) IgK chain [Mus musculus]
            Length = 110

Frame  3 hits (HSPs):         ____________________                        
                        __________________________________________________
Database sequence:     |        |        |        |        |         |    | 110
                       0       20       40       60       80       100

  Plus Strand HSPs:

 Score = 64 (22.5 bits), Expect = 7.7, P = 1.0
 Identities = 16/44 (36%), Positives = 24/44 (54%), Frame = +3

Query:    57 LRQDCT---RSSMRLVSFHSLFQLWWEELYNQEPACLIYSAHNM 179
             LRQ  T   R+S  + S+ + F  W+++   Q P  LIY A N+
Sbjct:    15 LRQRATISCRASESVDSYGNSFMYWYQQKPGQPPKLLIYRASNL 58


Parameters:
  filter=none
  matrix=BLOSUM62
  V=50
  B=50
  E=10
  gi
  H=1
  sort_by_pvalue
  echofilter

  ctxfactor=5.98

  Query                        -----  As Used  -----    -----  Computed  ----
  Frame  MatID Matrix name     Lambda    K       H      Lambda    K       H
   Std.    0   BLOSUM62                                 0.318   0.135   0.401  
   +3      0   BLOSUM62        0.318   0.135   0.401    0.341   0.148   0.561  
               Q=9,R=2         0.244   0.0300  0.180     n/a     n/a     n/a
   +2      0   BLOSUM62        0.318   0.135   0.401    0.353   0.159   0.536  
               Q=9,R=2         0.244   0.0300  0.180     n/a     n/a     n/a
   +1      0   BLOSUM62        0.318   0.135   0.401    0.366   0.169   0.638  
               Q=9,R=2         0.244   0.0300  0.180     n/a     n/a     n/a
   -1      0   BLOSUM62        0.318   0.135   0.401    0.362   0.158   0.610  
               Q=9,R=2         0.244   0.0300  0.180     n/a     n/a     n/a
   -2      0   BLOSUM62        0.318   0.135   0.401    0.334   0.142   0.474  
               Q=9,R=2         0.244   0.0300  0.180     n/a     n/a     n/a
   -3      0   BLOSUM62        0.318   0.135   0.401    0.357   0.164   0.538  
               Q=9,R=2         0.244   0.0300  0.180     n/a     n/a     n/a

  Query
  Frame  MatID  Length  Eff.Length     E    S W   T  X   E2     S2
   +3      0       96        96       10.  66 3  12 22  0.10    32
                                                    28  0.095   34
   +2      0       97        97       10.  66 3  12 22  0.10    32
                                                    28  0.097   34
   +1      0       97        97       10.  66 3  12 22  0.10    32
                                                    28  0.097   34
   -1      0       97        97       10.  66 3  12 22  0.10    32
                                                    28  0.097   34
   -2      0       97        97       10.  66 3  12 22  0.10    32
                                                    28  0.097   34
   -3      0       96        96       10.  66 3  12 22  0.10    32
                                                    28  0.095   34


Statistics:

  Database:  /usr/local/dot5/sl_home/beauty/seqdb/blast/nr
    Title:  nr
    Release date:  unknown
    Posted date:  4:06 PM CST Feb 28, 2001
    Format:  BLAST
  # of letters in database:  197,782,623
  # of sequences in database:  625,274
  # of database sequences satisfying E:  16
  No. of states in DFA:  590 (58 KB)
  Total size of DFA:  154 KB (192 KB)
  Time to generate neighborhood:  0.01u 0.00s 0.01t  Elapsed: 00:00:00
  No. of threads or processors used:  6
  Search cpu time:  103.43u 1.16s 104.59t  Elapsed: 00:00:18
  Total cpu time:  103.46u 1.18s 104.64t  Elapsed: 00:00:18
  Start:  Thu Jan 17 11:03:15 2002   End:  Thu Jan 17 11:03:33 2002

Annotated Domains Database: March 14, 2000
Release Date: March 14, 2000