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Abnormal cervical cytology and frequency of cervical infections in 35 HIV positive women related to severity of disease.

McCarthy KH, Johnson MA, Norman SG, Studd JW; International Conference on AIDS.

Int Conf AIDS. 1992 Jul 19-24; 8: B96 (abstract no. PoB 3058).

Royal Free Hospital, London, UK.

OBJECTIVE: To analyse cervical pathology in a cohort of HIV positive women attending a London teaching hospital in relation to disease progression. METHOD: The study is on going and controlled. All patients complete a lifestyle questionnaire, colposcopy, cervical smear, and genital infection screen are performed. The patients are reviewed 6 monthly. RESULTS: These are available for 35 consecutive HIV positive women. Nineteen of 34 had abnormal cytology on cervical smear (1 previous total abdominal hysterectomy). Fifteen of 35 had at least one genital infection, over half due to candida albicans. There is no significant difference in CD4 counts between those with abnormal smears and those without, and no correlation between severity of smear and CD4 count. There is no difference in frequency of abnormal smears in the different risk groups. The immigrant African population have a significantly increased frequency of genital infection compared with the drug users and heterosexual risk populations (p less than 0.05). There is no difference in median CD4 counts between the groups. Data on the HIV negative women recruited from our clinic providing HIV antibody results on the day of testing will be presented. CONCLUSIONS: Women with HIV infection have a high rate of cervical pathology in this group which is not dependent on the degree of immunosuppression measured by CD4 count.

Publication Types:
  • Meeting Abstracts
Keywords:
  • CD4 Lymphocyte Count
  • Colposcopy
  • Counseling
  • Female
  • HIV Infections
  • HIV Seropositivity
  • Humans
  • Hysterectomy
  • London
  • Vaginal Smears
  • epidemiology
  • surgery
Other ID:
  • 92401689
UI: 102199402

From Meeting Abstracts




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