WANG JR, WU JJ, MULDOON S, ROOD H, SCHACHTER J, JANG D, PINSON J, CHENG YM, CHANG CH, CHANG FM, CHERNESKY M; Interscience Conference on Antimicrobial Agents and Chemotherapy (41st : 2001 : Chicago, Ill.).
Abstr Intersci Conf Antimicrob Agents Chemother Intersci Conf Antimicrob Agents Chemother. 2001 Dec 16-19; 41: abstract no. D-2245.
National Cheng King University, Tainan, Taiwan Republic of China
BACKGROUND: C. trachomatis (Ct) and N. gonorrhoeae (Ng) are sexually transmitted infections, which when undiagnosed in the lower genital tract can ascend into the female reproductive organs with costly morbidity. Nucleic acid amplification tests such as LCR (LCx-Abbott) have enabled a clearer understanding of infection prevalence using non-invasive specimens such as first void urine (FVU). No prevalence studies have been undertaken recently in Taiwan, using these new sensitive tests. METHODS: We enrolled 553 women, 15-40 years of age, attending our University Hospital Clinic for gynecological problems. Endocervical swabs were collected for Ct (McCoy cells) and Ng (Martin-Lewis Agar); and LCx (Ct and Ng). FVU was collected for LCx (Ct and Ng). Consent and a patient information form were completed. RESULTS: Prevalence of infection in these Taiwanese women was 2.53% for Ct and 0.36% for Ng from June 1999 - December 2000. Infection detection occurred throughout the year and 1 person had a dual infection. None of the Ng cultures were positive and Ct culture detected 4 of the 14 infected women (28.5%). Both of the Ng infected women were LCx positive in the swab and urine. Swab testing detected 78.6% of the chlamydia infected women and FVU 71.4%, suggesting infections in different anatomic sites or inhibition in different specimen types. CONCLUSIONS: Both Ct and Ng are in low prevalence in our setting. LCx testing more than doubled the prevalence over culture but both cervical swabs and urines needed to be tested to yield the full prevalence level.
Publication Types:
Keywords:
- Cervix Uteri
- Chlamydia Infections
- Chlamydia trachomatis
- Cross-Sectional Studies
- Female
- Genitalia, Female
- Gonorrhea
- Humans
- Neisseria gonorrhoeae
- Taiwan
- urine
Other ID:
UI: 102268758
From Meeting Abstracts