Dunn AM, Cervia JS, Burgess A, Grassey C, Hinds G, Cunningham-Rundles S, Noel GJ; International Conference on AIDS.
Int Conf AIDS. 1996 Jul 7-12; 11: 319 (abstract no. Tu.B.2312).
Cornell University Medical College-The New York Hospital, New York, New York.
Objective: To examine the immunologic and clinical characteristics of P-HIV children who fail to thrive and compare those characteristics to a cohort of P-HIV children with normal growth. Methods: Analysis of 165 children born to HIV-infected mothers was conducted over a 19 month period assessing the following variables: age, sex, weight, height, serum albumin, CDC immunologic staging, use of anti-retrovirals, presence of a consistent primary caretaker, and development. FTT was defined as weight & height less than 5th% for age and a consistent primary caretaker was defined as an adult figure providing greater than 90% of the patient's care. Results: P-HIV infection was diagnosed in 89 children in this cohort. FTT occurred in 16 (18.0%) of 89 P-HIV children. Among seroreverters FTT occurred in only 4 children (5.3%; P is less than 0.01). Clinical and immunologic characteristics of P-HIV children with FTT and of P-HIV children with normal growth is shown in the table. Only 1 child in each group was hypoalbuminemic (less than 3.0 gm%). (table: see text) Conclusions: FTT is more frequent in P-HIV-infected children than in non-infected children born to HIV-infected mothers. Greater immunologic deficiency may be associated with FTT in P-HIV infants although differences between FTT and infants with normal growth were not statistically significant. The multi-factorial etiology of FTT in P-HIV infants is underscored by the observation that lack of a consistent caretaker and developmental delay are significantly greater in P-HIV children who fail to thrive when compared to P-HIV children with normal growth.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Adult
- Body Height
- Body Weight
- Child
- Child Abuse
- Developmental Disabilities
- Failure to Thrive
- HIV Infections
- HIV Seropositivity
- Health Personnel
- Humans
- Infant
- Mothers
- psychology
Other ID:
UI: 102218413
From Meeting Abstracts