Suttmann U, Selberg O, Melzer A, McMillan DC, Deicher H, Muller MJ; International Conference on AIDS.

Int Conf AIDS. 1993 Jun 6-11; 9: 77 (abstract no. WS-B34-4).

Medical School of Hannover, Dep. of Immunology, Germany.

Patients with advanced HIV infection are frequently malnourished and may even succumb to severe wasting. The weight loss in HIV-infected patients is characterised by a predominant loss of body cell mass. Since protein constitutes most of the body cell mass, this study investigates the response of malnourished HIV-infected patients to increasing amounts of protein intake. Six patients (five male, 1 female, age 38 +/- 9 ys [mean +/- SD], ideal body weight 76 +/- 16% [range 61-98%], 5 patients WR 6, 1 patient WR 4) were followed for a period of 10 days of controlled total parenteral nutrition. Resting energy expenditure (REE) was measured on the first day (Deltatrac TM Metabolic Monitor, Datex, Finland) and all patients received 1.5 x REE with increasing amounts of protein (0.6g/kg BW/d during day 2-4, 1.2g/kg BW/d during day 5-7, and 1.8g/kg BW/d during day 8-10) and non-protein calories being given as equal amounts of carbohydrate and fat. Only non-caloric oral fluid intake was allowed during study period. Mean nitrogen balance was calculated for each three-day period from daily urine and stool collections. Nitrogen balance data were analyzed by the extended Kruskal-Wallis-Test and following results were obtained: TABULAR DATA, SEE ABSTRACT VOLUME. High protein, total parenteral nutrition may induce positive nitrogen balance even in malnourished patients with advanced HIV-infection.

Publication Types:

• Meeting Abstracts

Keywords:

• AIDS Vaccines
• Acquired Immunodeficiency Syndrome
• Energy Metabolism
• Fat Emulsions, Intravenous
• Female
• Finland
• HIV Infections
• HIV Seropositivity
• Humans
• Male
• Malnutrition
• Nutritional Status
• Parenteral Nutrition, Total
• Proteins
• Rest
• Weight Loss

Other ID:

• 93336347

UI: 102205725

From Meeting Abstracts