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Seroepidemiology of HIV-infection in Frankfurt/FRG.

Doerr HW, Enzensberger R, Staszewski S; International Conference on AIDS.

Int Conf AIDS. 1989 Jun 4-9; 5: 100 (abstract no. T.A.P.10).

University Clinics Frankfurt, West Germany

Since 1985, about 2500 persons with HIV infection have been detected in the region of Frankfurt/FRG. The prevalence of HIV infection increases by 30-50 persons per month. Among them only 4 cases of HIV-2 infection were found until now (December 1988). Epidemiological analysis is restricted by the general acceptance of HIV tests and by varying medical care. Nevertheless, studies comparing age, sex and risk group distribution in AIDS patients and HIV-carriers detected during the last six months indicate a change in infection kinetics. Today the new HIV-carriers are increasingly found among iv drug users and prostitutes. 20% of all recently detected HIV carriers are females. 4.4% of 1808 prostitutes followed-up between 1985-1988 were found HIV positive. The probability of acquiring HIV infection outside the risk groups is still low. HIV infected persons were investigated for the seroprevalence of antibodies to opportunistic infections. Compared to HIV seronegative healthy persons without risk factors and prostitutes, HIV antibody carriers (asymptomatic, LAS and AIDS patients), presented increasing prevalence and titers of antibodies to HSV 1 and 2, VZV, CMV, EBV (VCA, EBNA), HBV (HBc, HBs), and treponema pallidum. The pattern of antibodies to opportunistic infections may support HIV markers of pathogenicity (e.g.p 24 antigen and antibody).

Publication Types:
  • Meeting Abstracts
Keywords:
  • Acquired Immunodeficiency Syndrome
  • Female
  • HIV
  • HIV Infections
  • HIV Seronegativity
  • HIV Seropositivity
  • Herpesvirus 3, Human
  • Herpesvirus 4, Human
  • Humans
  • Prevalence
  • Prostitution
  • Risk Factors
  • Seroepidemiologic Studies
  • Substance Abuse, Intravenous
  • immunology
Other ID:
  • 00028589
UI: 102176177

From Meeting Abstracts




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