US 7,445,798 B2
Populations of cells that express FLK-1 receptors
Ihor R. Lemischka, Princeton, N.J. (US)
Assigned to Trustees of Princeton University, Princeton, N.J. (US)
Filed on Aug. 11, 2003, as Appl. No. 10/639,603.
Application 08/601891 is a division of application No. 08/252498, filed on Oct. 31, 1994, abandoned.
Application 08/252498 is a division of application No. 08/055269, filed on Apr. 30, 1993, granted, now 5,367,057.
Application 08/055269 is a division of application No. 07/977451, filed on Nov. 19, 1992, granted, now 5,270,458.
Application 10/639603 is a continuation of application No. 09/208786, filed on Dec. 10, 1998, abandoned.
Application 09/208786 is a continuation of application No. 09/021324, filed on Feb. 10, 1998, granted, now 5,912,133.
Application 09/021324 is a continuation of application No. 08/601891, filed on Feb. 15, 1996, granted, now 5,747,651.
Application 07/977451 is a continuation in part of application No. 07/975049, filed on Nov. 12, 1993, abandoned.
Application 07/975049 is a continuation in part of application No. 07/906397, filed on Jun. 26, 1992, granted, now 5,621,090.
Application 07/906397 is a continuation in part of application No. 07/813593, filed on Dec. 24, 1991, granted, now 5,185,438.
Application 07/813593 is a continuation in part of application No. 07/793065, filed on Nov. 15, 1991, abandoned.
Application 07/793065 is a continuation in part of application No. 07/728913, filed on Jun. 28, 1991, abandoned.
Application 07/728913 is a continuation in part of application No. 07/679666, filed on Apr. 02, 1991, abandoned.
Prior Publication US 2005/0003365 A1, Jan. 06, 2005
Int. Cl. A61K 35/28 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01)
U.S. Cl. 424—577  [424/93.7; 424/143.1; 424/144.1; 424/152.1; 424/153.1; 424/173.1; 435/2; 530/388.2; 530/388.22; 530/388.7] 4 Claims
 
1. An isolated population of cells that express FLK-1 on their surface, wherein the population is isolated by a method comprising binding the cells to a polyclonal or monoclonal antibody specific for the FLK-1, wherein the FLK-1 is encoded by SEQ ID NO:5, and isolating the cells that are bound to the antibody from cells that are unbound to the antibody,
wherein said isolated population of cells is bound to said antibody.