Zander K, Jager H, Palitzsch M, Poppinger J, von Steinbuchel N, Bullinger M; International Conference on AIDS.
Int Conf AIDS. 1993 Jun 6-11; 9: 79 (abstract no. WS-B36-4).
Univers. Munich/Sciencia Health Res., Germany.
OBJECTIVE: Assessment of HRQL indices is important in trials on non-curative treatments of HIV disease. Factors which influence the patient's HRQL rating could be particularly considered in the development of palliative treatments. METHODS: 100 HIV patients (84 m., 16 f.) participated (30 CDC II/III, 70 CDC IV; 245 +/- 251 CD4 after 5.2 +/- 3 years infected). N = 58 had anti-retroviral medication. Cross-sectional HRQL rating was performed by a new German version of the MOS-HIV, PGWB, HRQL-VAS, and the MLDL (Heinisch et al. 1991). Further ratings included a HIV symptom list, the POMS and a coping scale (FKV). Observers rated Karnofsky score and concomitant pathology. RESULTS: Mean global HRQL self-ratings ranged between 50-61% of max. Lowest scores were obtained for overall health, energy/fatigue and mental health on the MOS-HIV, highest for social functioning. Leading physical and mental symptoms contributing to HRQL were fatigue (30% max. severity), tiredness, weakness, malaise, depression, insomnia, and anxiety (22%). However, "active coping" was the preferred--and "depressive coping" the least preferred coping style. Most help was expected from "cooperation with physician", "firmly fighting disease" and "seeking information". CONCLUSION: General physical and frequently mental symptoms appeared to strongly influence HRQL in this study population. Therapies with related benefits may be investigated by means of HRQL psychometry.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Adaptation, Psychological
- Affect
- Depression
- Evaluation Studies
- Fatigue
- HIV Infections
- HIV Seropositivity
- Health
- Health Status
- Health Status Indicators
- Humans
- Life
- Quality of Life
Other ID:
UI: 102205736
From Meeting Abstracts