AHCPR announces new funding opportunities
The Agency for Health Care Policy and Research has announced
three new funding opportunities, which are described below. The
first announcement is for development of computerized decision
support systems for health providers followed by expansion of
quality measures and research on referrals from primary to
specialty care.
Applications may be submitted by domestic and foreign nonprofit
organizations, public and private, including universities,
clinics, units of State and local governments, nonprofit firms
and foundations, or a consortium of organizations. Women,
racial/ethnic minority individuals, and persons with disabilities
are encouraged to apply as principal investigators.
Grant application kits, which include the PHS 398 application and
instructions are available from
the NIH Grants site: http://grants.nih.gov/grants/funding/phs398/phs398.html.
Applications should be sent to the Division of Research Grants,
National Institutes of Health, 6701 Rockledge Drive, Room 1040 -
MSC 7710, Bethesda, MD 20892-7710 (20817 for express mail). See
the individual announcement of interest for the application due
date.
AHCPR welcomes the opportunity to clarify any issues or questions
from potential applicants. For programmatic questions, contact
the individual listed in the announcement of interest. Direct
inquiries regarding fiscal matters to Mable L. Lam, Chief of
Grants Management Staff; telephone (301) 427-1448; E-mail
MLam@ahrq.gov.
Decision Support Systems
AHCPR invites applications to conduct research on computerized
decision support systems (CDSS) as a component of electronic
medical record systems. The goals of this research are to assist
providers' decisionmaking and improve the cost-effectiveness of
health services. Applicants should address one or more of the
following elements for incorporating CDSS in electronic medical
records: (1) use of clinical practice guidelines in decision
support systems while security and confidentiality of patient
care data are maintained in different patient care settings, (2)
the impact of CDSS on the effectiveness of the patient care
process, patient outcomes of care, and/or the cost of care, and
(3) identification and testing of factors that influence
practitioner use of CDSS.
The administrative and funding instrument will be the research
grant (R01) mechanism. The total requested project period may
not exceed 3 years, and the earliest anticipated award date is
September 1, 1996.
Depending on the availability of funds, AHCPR expects to award up
to approximately $1.5 million in FY 1996 to support the first
year of approximately 6 to 10 projects under this RFA. This is a
one-time solicitation, and funding beyond the initial budget
period will depend on annual progress reviews by AHCPR and the
availability of funds.
Applications submitted under this RFA must be received in the
Division of Research Grants, NIH, by June 12, 1996. Written and
telephone inquiries concerning this RFA are encouraged. Direct
inquiries regarding programmatic issues to:
J. Michael Fitzmaurice, Ph.D.,
Center for Information Technology;
telephone: (301) 427-1227;
E-mail: MFitzmau@ahrq.gov
This announcement (RFA HS-96-007; AHCPR Publication No. 96-R061)
appeared in the NIH Guide to Grants and Contracts on March 29,
1996.
Expansion of Quality Measures (Q-SPAN)
AHCPR announces the availability of cooperative agreements to
develop and test quality of care measures. These projects are
expected to expand the conceptual and methodological basis for
developing quality measures and produce relevant, feasible,
reliable, valid, and rigorously tested sets of new quality
measures for comparison across different sites. The long-term
goal of this effort is to strengthen the science base underlying
the evolution of performance measures while expanding the range
of available, ready-to-use measures that address the continuum of
care.
The administrative and funding instrument will be the cooperative
agreement (U18), in which substantial AHCPR scientific and
programmatic involvement with the awardee(s) is anticipated
during the performance of the project. The total project period
for each project may not exceed 5 years. The earliest anticipated
award date is September 1, 1996.
Depending on the availability of funds, AHCPR expects to award up
to $3 million in fiscal year 1996 for several short-term and
long-term projects. Funded projects will reflect a balance
between short-term projects (1 to 3 years), which can rapidly
produce performance measures using existing knowledge and
instruments, and projects that require a longer developmental
period (3 to 5 years). This is a one-time solicitation.
Applications in response to this RFA must be received in the
Division of Research Grants, NIH, by June 12, 1996. Written and
telephone inquiries concerning this RFA are encouraged. Direct
programmatic inquiries to: Elinor Walker,
Center for Quality Measurement and Improvement,
Q-SPAN Project Officer; telephone: (301) 427-1311.
This announcement (RFA HS-96-004; AHCPR Publication No. 96-0036)
appeared in the NIH Guide to Grants and Contracts on March 15,
1996.
Referrals From Primary to Specialty Care
AHCPR invites applications to conduct research related to patient
referrals from primary care to specialty care. AHCPR is
particularly interested in studies that (1) describe how changes
in health care organization affect referral practices, and/or (2)
measure quality of care, examine economic implications, and study
other outcomes resulting from decisions by primary care providers
who refer or do not refer patients to specialty providers.
The goal of this solicitation is to inform the policies related
to referral within health plans and strengthen the science base
underlying the evolution and use of referral protocols in
ambulatory health care settings. Applicants are encouraged to
form partnerships or consortia involving health plans that can
provide the data and technical capabilities to study referral
patterns and facilitate access to delivery settings in which the
outcomes of referrals can be evaluated.
The administrative and funding instrument will be the cooperative
agreement (R01) in which substantial AHCPR scientific and
programmatic involvement with awardees is anticipated during the
performance of the project. The total project period may not
exceed 2 years, and the earliest anticipated award date is
September 1, 1996.
Depending on the availability of funds, AHCPR expects to award up
to $1.5 million for the first year of projects under this RFA.
This is a one-time solicitation.
In September 1995, AHPCR's Center for Primary Care Research
convened a conference, "Research at the Interface of Primary and
Specialty Care." The purposes of the conference were to: (1)
assess the current state of research related to consultation and
referral; and (2) obtain suggestions regarding the most important
referral-related questions to be addressed by future research.
Potential applicants are encouraged to request a copy of the
conference summary (AHCPR Publication No. 96-0034) from AHCPR. A
brief review of the conference appears in the Journal of the
American Medical Association (274, p. 1419, November 8,
1995).
Applications submitted under this RFA must be received in the
Division of Research Grants, NIH, by June 12, 1996. Direct
programmatic inquiries to: David Lanier, M.D.,
Center for Primary Care Research; telephone: (301) 427-1567;
E-mail: DLanier@ahrq.gov
This announcement (RFA HS-96-006; AHCPR Publication No. 96-R056)
appeared in the NIH Guide to Grants and Contracts on March
15, 1996.
AHCPR and Kaiser to cosponsor conference on
communicating with consumers about health care quality
Mark your calendars now for the fall 1996 conference, Value and
Choice: Providing Consumers with Information on the Quality of
Health Care. The Henry J. Kaiser Family Foundation and the Agency
for Health Care Policy and Research will cosponsor the
conference, which will bring together consumer advocates, public
and private purchasers and coalitions, managed care plan
executives, health care providers, researchers, and others
interested in communicating with consumers about health care. The
conference will be held October 29-30, 1996, at the Doubletree
Pentagon City Hotel, which is adjacent to Washington, DC's
National Airport in Arlington, VA. Examples of questions to be
addressed in presentations, workshops, and exhibits include:
- What kinds of information on health care quality do
consumers want and use in making health care choices?
- What do we know about the most effective formats for
providing quality information to consumers?
- What can other disciplines—such as marketing,
education, and communications—tell us about how people use
complex information to make choices?
- Do certain population groups have special information
needs?
- What about differences in language, income and education
levels, or disability?
- To whom do consumers turn for information and help in
understanding health care choices?
- How do emerging technologies such as the Internet affect the
kinds of quality information consumers use?
A call for papers and exhibits is now in development and will be
available by June 3 from AHCPR's Home Page (http://www.ahcpr.gov)
and the Kaiser Family Foundation's Home Page
(http://www.kff.org). Persons without Internet access may request
a copy of the announcement by mail or fax from Health Systems
Research, Inc., 2021 L Street N.W., Suite 400, Washington, DC
20036; fax (202) 728-9469.
AHCPR releases second installment of the hospital inpatient
database and the first three HCUP-3 Pocket Guides
Hospital inpatient database. The Agency for Health Care Policy
and Research recently released the Nationwide Inpatient Sample,
Release 2, which presents 1993 discharge data from a 20 percent
sample of U.S. hospitals in 17 States.
The Nationwide Inpatient Sample (NIS), Release 2, is part of the
Healthcare Cost and Utilization Project (HCUP-3), sponsored by
the Agency for Health Care Policy and Research. It is based on a
stratified probability sample of hospitals, with sampling
probabilities proportional to the number of U.S. community
hospitals in each stratum.
NIS, Release 2 is drawn from 17 geographically dispersed States
and contains information on all inpatient stays from over 900
hospitals, totaling about 6.5 million records in 1993. The States
in NIS, Release 2, are Arizona, California, Colorado,
Connecticut, Florida, Illinois, Iowa, Kansas, Maryland,
Massachusetts, New Jersey, New York, Oregon, Pennsylvania, South
Carolina, Washington, and Wisconsin.
Inpatient stay records include clinical and resource use
information typically available from discharge abstracts.
Hospital and discharge weights are provided for producing
national estimates. The NIS can be linked to hospital-level data
from the American Hospital Association's Annual Survey of
Hospitals and county-level data from the Bureau of Health
Professions' Area Resource File (except for hospitals in Kansas
and South Carolina).
Access to the NIS is open to all researchers who sign data use
agreements. Uses are limited to research and aggregate
statistical reporting.
The NIS, Release 2, is available from the National Technical
Information Service (NTIS accession no. PB96-501325, $160.00 for
a set of six CDs.
The NIS, Release 1, which spans the years 1988 to 1992, also is
available from NTIS. The cost for the complete, 5-year, 26-CD set
is $300, which includes full documentation and tools for SAS and
SPSS users (PB 95-503710).
Pocket guides. The first three HCUP-3 Pocket Guides are now
available from AHCPR. They present summary statistics from the
NIS in an easy-to-use form. The 4-1/2" x 7" guides contain
summary national statistics on the number and percent of
discharges, mean length of stay, and mean total charges for
hospital stays in 1992, organized by principal diagnosis,
principal procedure, and diagnosis-related group. The booklets
are designed for use by researchers, hospital planners, market
analysts, policymakers, and others who need a ready reference to
information about inpatient hospital care in the United
States.
Copies of these and future Pocket Guides in the series are
available from AHCPR. Request the Pocket Guide for
Diagnosis-Related Groups (AHCPR Publication No. 96-0028),
Pocket Guide for Principal Diagnoses (AHCPR Publication
No. 96-0029), and/or Pocket Guide for Principal Procedures (AHCPR
Publication No. 96-0030).
The 1993 NIS data include 6.5 million inpatient stays in 900 hospitals in 17 States, clinical and
resource use variables usually found on discharge abstracts, weights to produce national
estimates, and hospital identifiers to link with the American Hospital Association's Survey of
Hospitals. All in a 6-CD set for $160. To order, contact the National Technical Information Service.
For more information on the NIS or HCUP-3, phone 866-290-HCUP (4287), toll-free, or E-mail
hcup@ahrq.gov.
New publications available from NTIS
The following publications and final reports are now available
from the National Technical Information Service.
Assessment of Strategies for Prostate Cancer Screening. AHCPR
grant HS07230, 6/1/92 to 7/31/94. Gerald W. Chodak, M.D.,
University of Chicago, Chicago, IL.
Although routine screening for prostate cancer has become
widespread in recent years, no studies have demonstrated that
such screening is effective in improving early detection or
lowering mortality. Not only does routine screening increase
health care costs, it also may result in unnecessary treatment
and complications. A randomized screening study is underway, but
results are not expected for 10 to 15 years. In the interim,
these researchers developed a comprehensive decision model and
tracked a cohort of 50-year-old men who were subjected to
alternative prostate cancer screening policies. This is the first
such model to include the impact of tumor grade and stage on
outcome. Preliminary results show that over a range of
assumptions, screening will reduce cancer mortality by
approximately 20 percent, but that costs will be large in terms
of health care dollars, morbidity, and unnecessary treatment.
(Abstract, computer program appendix, executive summary, and
final report; NTIS accession no. PB96-153887, 45 pp; $21.50
paper, $10.00 microfiche)
Bittersweet: The Transformation of Diabetes into a Chronic
Illness in 20th Century America. AHCPR grant HS07476, 9/1/92 to
11/30/93. John C. Feudtner, Ph.D., University of Pennsylvania,
Philadelphia, PA.
The lives of many juvenile diabetes patients in America have been
shaped by the development of new medical interventions that have
transformed diabetes from an acute and lethal disease into a
chronic and often debilitating condition. In this dissertation,
the author draws on a vast array of medical records and letters
exchanged between diabetic patients and/or their family members
and the staff of the Joslin Clinic in Boston, MA, to trace the
experiences of these patients and their caregivers during a time
of rapid development in diabetes therapies. (Abstract and
executive summary of dissertation; NTIS accession no.
PB96-153879, 6 pp; $10.00 paper, $10.00 microfiche)
Breast Cancer Screening Policy and Practice. AHCPR grant
HS06545, 9/1/91 to 9/29/95. Thomas R. Taylor, Ph.D., University
of Washington, Seattle, WA.
This project involved the following four objectives and
conclusions: (1) Test the efficacy of an educational intervention
to improve physicians' decisions about mammography screening in
women ages 40 to 49 and 50 to 80 years; two interventions were
tested and found ineffective in changing the screening behavior
of physicians. (2) Predict mammography screening behavior of
family physicians using survey data; for all women, the
physician's sex and recommended interval between mammograms were
significantly associated with screening rates, as was practice
configuration for women 40 to 49 years of age and, for older
women, the proportion of patients having Medicare; survey data
were not reliable in predicting actual behavior. (3) Assess the
relationship between physicians' risk preference, sex, and
screening; no association was found between female sex, screening
rates, and risk preferences. (4) Assess the effects of continuing
medical education and cognitive feedback on physicians' internal
policies for mammography screening; there was no evidence that
CME or cognitive feedback training had an effect on internal
policies. (Abstract, executive summary, and final report; NTIS
accession no. PB96-156948, 67 pp; $25.00 paper, $10.00
microfiche)
Cognitive Errors Concerning Personal Health. AHCPR grant
HS06660, 2/1/91 to 1/31/95. Robert T. Croyle, Ph.D., M.D.,
University of Utah, Salt Lake City, UT.
Six experiments were conducted to examine the accuracy of
personal health judgment and the recall of health events in
adults in the community. After the participants' cholesterol
levels were measured and communicated to them, the researchers
contacted them by telephone at various intervals and asked them
to recall their cholesterol readings. Results indicate that
participants were overconfident in recalling their cholesterol
levels. They minimized the seriousness of having a cholesterol
level above desirable range. On average, participants recalled
their cholesterol levels as being lower than they actually were.
In addition, distress was most likely among individuals in the
high-risk group who had expected to receive a lower cholesterol
score. (Abstract and executive summary; NTIS accession no.
PB96-138748, 20 pp; $17.50 paper, $9.00 microfiche)
Computer Support for Protocol-Directed Therapy. AHCPR grant
HS06330, 3/1/90 to 8/31/95. Mark A. Musen, M.D., Ph.D., Stanford
University, Stanford, CA.
This project addressed the automation of protocol-based care for
clinical trials. The researchers developed a computer-based
patient record system known as T-HELPER I that allows health care
workers to (1) enter and review clinical data required for the
care of people who have AIDS and HIV infection and (2) browse
through textual protocol documents online. A more advanced
system, T-HELPER II, adds to the functionality available in
T-HELPER I situation-specific clinical advice regarding patients'
potential eligibility for clinical trials and the therapy
patients should receive when they are already participating in
clinical trials. Much of this work involved developing the
computational methods required by T-HELPER II to automate aspects
of protocol-based care (for example, the development of novel
approaches to reasoning about protocol-directed therapy and about
determining eligibility for new protocols). These systems are
currently being evaluated in a controlled trial at a
county-operated AIDS clinic to measure whether the additional
functionality of the T-HELPER II system leads to enhanced accrual
of patients to clinical trials and to changes in the attitudes of
health care workers regarding computer-based decision support
systems. (Abstract, executive summary, and final report; NTIS
accession no. PB96-138730, 33 pp; $17.40 paper, $9.00
microfiche)
Continuity of Care for African and Hispanic Americans. AHCPR
grant HS08104, 9/1/94 to 2/29/96. Llewellyn J. Cornelius, Ph.D.,
University of Maryland School of Social Work, Baltimore,
MD.
This study used data from the 1987 National Medical Expenditure
Survey (NMES) to examine African and Hispanic Americans' reliance
on a regular provider for their medical care. Results showed that
Hispanic Americans had greater continuity of care with a regular
physician than white or African Americans. Furthermore, persons
with low continuity of care had one-third higher health care
expenditures per year, on average, than those with high
continuity of care. Finally, the availability of evening and
weekend care enhanced the degree of continuity for white
patients; continuity was enhanced among Hispanic patients when
evening care was available. When other characteristics of care
were accounted for, the degree of continuity of care varied by
both the race/ethnicity of patients and the race/ethnicity and
sex of regular physicians. (Abstract, executive summary, and
final report; NTIS accession no. PB96-145453, 41 pp; $17.50
paper, $9.00 microfiche)
Determining Usual Blood Pressure of Older Adults in Primary
Care. AHCPR grant HS07662, 2/1/93 to 7/31/96. Kevin A. Pearce,
M.D., M.P.H., Bowman Gray School of Medicine, Wake Forest
University, Winston-Salem, NC.
The objective of this observational, cross-sectional study was to
examine the accuracy of routine office blood pressure (OBP)
readings by nurses and standardized OBP readings, with the aim of
improving the estimation of usual blood pressure (BP) in primary
care settings. For this study, 75 randomly selected primary care
patients made six office visits for OBP measurements and had
24-hr arterial BP (ABP) monitoring done twice. Routine OBP
readings by nurses and standardized readings by a research
assistant had nearly equal accuracy with respect to mean ABP. The
correlation between mean OBP and mean 24-hour ABP rose with the
average number of visits, with most of the gain obtained within
three visits. Defining usual BP as mean awake ABP did not change
the results, and clinical and demographic variables had no effect
on the relationships between OBP and ABP. The researchers
concluded that readings from at least three office visits should
be averaged to estimate usual BP. However, significant error in
this estimation persists after six visits. ABP monitoring
probably provides unique information about usual BP that cannot
be captured by repeated OBP readings. Routine OBP readings can be
substituted for standardized OBP readings in observational
research. (Abstract, executive summary, and final report; NTIS
accession no. PB96-138755, 64 pp; $19.50 paper, $9.00
microfiche)
Directory of Minority Health and Human Services Data
Resources.
This directory was produced for policymakers, researchers, and
the public as a reference document on data resources within the
U.S. Department of Health and Human Services (HHS) that contain
race and ethnicity information. It includes data resources with
widespread applications. Databases from continuing departmental
projects or program administrative and evaluation activities that
have broad utility are included. These projects and systems
include repeated surveys and disease registries either maintained
or sponsored by HHS. Databases from one-time studies or data
collections are also included when they contain data with broad
or multiple applications. This directory contains information on
databases compiled and/or maintained by each of the HHS
agencies, including the Social Security Administration, which at
the time this report was compiled was a component of HHS. (NTIS
accession no. PB96-100185, 288 pp; $49.00 paper, $19.50
microfiche)
Predictors of Back Problems and Back-Related Disability and
the Effects of Comorbidity and Other Factors on Back-Related
Health Care Utilization in the United States. AHCPR grant
HS07968, 9/1/93 to 5/31/95. Eric L. Hurwitz, Ph.D., University of
California, Los Angeles, CA.
The objective of the study was to use a probability sample to
identify predictors of back problems and back disability and to
assess the effects of comorbidity and other factors on the use of
back-related health care in the adult population of the United
States. Cross-sectional analyses were performed using data from
respondents of the 1989 National Health Interview Survey (NHIS).
Adult respondents who were between the ages of 25 and 64, males,
non-high school graduates, unemployed, living in the West, with
disabling non-back morbidities, and with body mass index and
weight in the upper 50th percentile were more likely to have a
disabling back problem than to have no back problem. Those with
back disabilities who reported non-disabling comorbidities were
much more likely to have sought back care compared with those who
did not have any comorbidities. Among all adults with back
problems, those with disabling comorbidities were less likely to
have sought back care. Among the back-care users, those with
disabling comorbidities and back-related restricted-activity days
were less likely to have sought chiropractic care compared with
primary medical care. Those who were male, high-school educated,
single, and employed, and who made more than nine doctor visits
in the past year were more likely to use chiropractic care than
primary medical care. (Abstract and executive summary of
dissertation; NTIS accession no. PB96-145438, 13 pp; $17.50
paper, $9.00 microfiche)
Reducing Error in Mortality Models for ICU Patients. AHCPR
grant HS06026, 9/1/88 to 9/29/93. Stanley Lemeshow, Ph.D.,
University of Massachusetts, Amherst, MA.
Four new mortality probability models were developed for
characteristics at time of admission to the ICU and at 24, 48,
and 72 hours postadmission. The models performed well in the
developmental and validation samples of a study cohort alone and
combined with an international multisite cohort of 19,124
patients. Model performance deteriorated with time from
admission. In computer simulations varying the frequency of
patient-mix variables, the more commonly occurring variables
affected performance negatively more rapidly than less frequently
occurring variables. (Abstract, executive summary, and final
report; NTIS accession no. PB96-157151, 99 pp; $25.00 paper,
$14.00 microfiche)
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