Signal transduction proteins encoded in 167 bacterial and archaeal genomesa

A web supplement to the paper "A census of membrane-bound and intracellular signal transduction proteins in bacteria:
Bacterial IQ, extroverts and introverts
" by M. Y. Galperin, published in BMC Microbiology 2005, 5:35. Abstract. Full text (PDF). Previous version of this table, prepared for the review "Bacterial signal transduction network in a genomic perspective"
by M. Y. Galperin, published in Environ. Microbiol. 2004, 6, 552-567. Abstract. Full text (PDF) .

The first variant of this table, prepared for the review by M. Y. Galperin, A. N. Nikolskaya, and E. V. Koonin
"Novel domains of the prokaryotic two-component signal transduction system",
published in FEMS Microbiol. Lett. 2001, 203, 11-21. Abstract. Full text (PDF).

Please send your corrections, questions and comments to Michael Galperin.

No.
Organism name
Phylum
GenBank entry
All proteins
 HisKin 
 MCP 
 STYK 
GGDEF
 EAL 
HD-GYP
AC1
AC2
AC3 
Total
TM
%TM
Actinobacteria                              
1
Streptomyces coelicolor
Actino
AL645882
8154
95*(84)
-
37(18)
7*(2)
5(2)
1(1)
-
-
1(0)
142
105
74%
2
Streptomyces avermitilis
Actino
BA000030
7671
78(67)
-
35(16)
7*(2)
5(2)
1(1)
-
-
1(0)
123
86
70%
3
Nocardia farcinica
Actino
AP006618
5924
36(31)
-
25(14)
8(2)
2(1)
-
-
-
4(2)
73
49
67%
4
Mycobacterium avium
Actino
AE016958
4350
19(16)
-
12(7)
4*(2)
3(1)
1(0)
-
-
12(7)
49
32
65%
5
Mycobacterium tuberculosis
Actino
AL123456
3927
14*(10)
-
13(8)
1(0)
2(0)
-
-
-
16(6)
46
24
52%
6
Mycobacterium bovis
Actino
BX248333
3920
13*(10)
-
13(7)
1(0)
2(0)
-
-
-
16(6)
45
23
51%
7
Symbiobacterium thermophilum
Actino
AP006840
3337
27(21)
13*(13)
1(1)
9(4)
3(2)
4(0)
-
-
-
54
39
72%
8
Corynebacterium glutamicum
Actino
BA000036
2993
13(12)
-
4(2)
1(1)
1(1)
-
-
-
1(1)
19
16
84%
9
Corynebacterium efficiens
Actino
BA000035
2950
13(13)
-
4(3)
-
-
-
-
-
1(1)
18
17
94%
10
Propionibacterium acnes
Actino
AE017283
2297
12(11)
-
4(3)
-
-
-
-
-
-
16
14
88%
11
Corynebacterium diphtheriae
Actino
BX248353
2272
11(11)
-
4(2)
-
-
-
-
-
1(1)
16
14
88%
12
Leifsonia xyli
Actino
AE016822
2030
16(15)
-
6(6)
-
-
-
-
-
-
22
21
95%
13
Bifidobacterium longum
Actino
AE014295
1727
9(8)
-
7(6)
-
-
-
-
-
-
16
14
88%
14
Mycobacterium leprae
Actino
AL450380
1605
5(4)
-
6(3)
3(1)
2(0)
-
-
-
4(1)
19
9
47%
15
Tropheryma whipplei
Actino
BX072543
783
2(1)
-
4(4)
-
-
-
-
-
-
6
5
83%
Cyanobacteria
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
16
Nostoc sp. PCC 7120
Cyano
BA000019
6055
134(40)
3(2)
52(15)
14(4)
7(2)
2(0)
-
-
6(2)
212
63
30%
17
Gloeobacter violaceus
Cyano
BA000045
4430
46(16)
-
20(9)
1(0)
-
1(0)
-
1(0)
1(0)
70
25
36%
18
Synechocystis sp. PCC 6803
Cyano
BA000022
3166
46(16)
4(3)
13(5)
22(5)
13(2)
2(0)
-
-
3(1)
94
30
32%
19
Synechococcus elongatus PCC 6301
Cyano
AP008231
2525
15(4)
2(2)
8(4)
17(8)
9(4)
2(0)
-
-
2(2)
47
21
45%
20
Synechococcus sp. WH 8102
Cyano
BX548020
2517
6(2)
-
3(3)
-
-
-
-
-
-
9
5
56%
21
Thermosynechococcus elongatus
Cyano
BA000039
2475
19(6)
3*(1)
17(7)
9*(0)
5(0)
1(0)
-
-
2(1)
51
15
29%
22
Prochlorococcus marinus CCMP1375
Cyano
AE017126
1882
5(2)
-
3(2)
-
-
-
-
-
-
8
4
50%
Alpha-proteobacteria
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
23
Bradyrhizobium japonicum
Alpha
BA000040
8317
92(59)
35*(31)
4*(2)
35(24)
27(17)
3(0)
-
-
37(12)
210
130
62%
24
Mesorhizobium loti
Alpha
BA000012
7275
62*(36)
1(1)
3(1)
32(17)
18(10)
1(0)
-
-
12*(1)
113
57
50%
25
Sinorhizobium meliloti 
Alpha
AL591688
6205
48(32)
9(7)
2(0)
17*(9)
13*(6)
-
-
-
28(12)
107
61
57%
26
Agrobacterium tumefaciens
Alpha
AE008688
5402
53(32)
20(14)
2(1)
27*(17)
14*(10)
1(0)
-
-
3(2)
109
69
63%
27
Rhodopseudomonas palustris
Alpha
BX571963
4813
66(35)
29(25)
5(3)
36(21)
18(9)
2(0)
-
-
7(4)
149
90
60%
28
Silicibacter pomeroyi 
Alpha
CP000031
4252
23(18)
-
2(1)
5(3)
2(1)
-
-
-
11(3)
42
25
60%
29
Caulobacter crescentus
Alpha
AE005673
3737
62(39)
18*(12)
2(1)
10*(4)
10(5)
-
-
-
3(1)
98
59
60%
30
Brucella suis
Alpha
AE014291
3271
21(17)
-
2(1)
8(6)
5(4)
-
-
-
-
33
26
79%
31
Brucella melitensis
Alpha
AE008917
3198
22(13)
-
2(1)
9(6)
5(4)
-
-
-
-
35
22
63%
32
Zymomonas mobilis
Alpha
AE008692
1998
15(10)
3(2)
1(1)
4(3)
3(1)
-
-
-
-
24
16
67%
33
Bartonella henselae
Alpha
BX897699
1488
11(9)
-
1(1)
1(1)
1(1)
-
-
-
-
13
11
85%
34
Rickettsia conorii 
Alpha
AE006914
1374
5(4)
-
1(0)
1(0)
1(1)
-
-
-
-
8
4
50%
35
Wolbachia endosym-biont of Drosophila
Alpha
AE017196
1195
2(1)
-
1(1)
1(0)
-
-
-
-
-
4
2
50%
36
Bartonella quintana
Alpha
BX897700
1142
11(9)
-
1(1)
1(1)
1(1)
-
-
-
-
13
11
85%
37
Anaplasma marginale
Alpha
CP000030
949
3(3)
-
1(1)
1(0)
-
-
-
-
-
5
4
80%
38
Rickettsia typhi 
Alpha
AE017197
838
4(4)
-
1(0)
1(0)
1(1)
-
-
-
-
7
5
71%
39
Rickettsia prowazekii 
Alpha
AJ235269
835
4(4)
-
1(0)
1(0)
1(1)
-
-
-
-
7
5
71%
Beta-proteobacteria
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
40
Burkholderia pseudomallei
Beta
BX571965
5728
46(36)
21(21)
4(3)
10(8)
11(4)
2(0)
-
1(0)
-
90
68
76%
41
Ralstonia solanacearum
Beta
AL646052
5116
44(37)
22(22)
3(1)
22*(16)
14(6)
2(0)
-
1(0)
-
98
77
79%
42
Bordetella bronchiseptica
Beta
BX470250
4994
25(21)
8(7)
4(3)
15(9)
9(5)
2(1)
-
-
-
58
44
76%
43
Burkholderia mallei
Beta
CP000011
4764
37(27)
17(17)
3(2)
8(7)
8(4)
2(0)
-
-
-
71
53
75%
44
Azoarcus sp. EbN1
Beta
CR555306
4603
42(28)
2(2)
7(3)
26(11)
23(7)
5(1)
-
-
1(0)
87
46
53%
45
Chromobacterium violaceum
Beta
AE016825
4407
50(32)
42(33)
4(3)
43(20)
26(7)
11(0)
-
-
-
160
91
57%
46
Bordetella parapertussis
Beta
BX470249
4185
22(18)
6(6)
4(3)
13(8)
9(5)
2(1)
-
-
-
51
38
75%
47
Bordetella pertussis
Beta
BX470248
3436
18(16)
5(5)
3(2)
7(3)
3(1)
1(0)
-
-
-
35
26
74%
48
Nitrosomonas europaea
Beta
AL954747
2461
15(11)
3(3)
2(1)
6(3)
9(3)
-
-
-
3(1)
34
20
59%
49
Neisseria meningitidis
Beta
AE002098
2079
5(5)
-
1(1)
-
-
-
-
-
-
6
6
100%
Gamma-proteobacteria
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
50
Pseudomonas syringae
Gamma
AE016853
5608
69*(42)
48*(41)
8(2)
35(18)
21(14)
1(0)
1(0)
-
-
164
109
67%
51
Pseudomonas aeruginosa
Gamma
AE004091
5567
63(45)
26(23)
8(2)
33(19)
21(14)
3(0)
1(0)
-
1(1)
140
96
69%
52
Photobacterium profundum
Gamma
CR354531
5480
53(43)
39(37)
8(3)
32*(18)
16(10)
2(0)
1(0)
1(0)
-
142
105
74%
53
Pseudomonas putida
Gamma
AE015451
5350
67(44)
27(22)
5(1)
36(21)
21(11)
2(1)
1(0)
-
-
142
90
63%
54
Escherichia coli O157:H7
Gamma
BA000007
5253
29(27)
5(5)
3(2)
19(12)
14(10)
-
1(0)
-
-
66
51
77%
55
Vibrio vulnificus CMCP6
Gamma
AE016795
5024
51(40)
52(43)
4(1)
66(38)
33(14)
13(4)
1(0)
-
-
200
126
63%
56
Vibrio parahaemolyticus
Gamma
BA000031
4832
50(42)
30(26)
6(2)
44*(27)
29(14)
5(1)
1(0)
1(0)
-
150
102
68%
57
Salmonella enterica serovar Typhi 
Gamma
AL513382
4758
30(28)
6(4)
3(1)
12(11)
16(11)
-
1(0)
-
-
61
50
82%
58
Photorhabdus luminescens
Gamma
BX470251
4683
18(16)
2(2)
1(1)
-
-
-
1(0)
-
-
22
19
86%
59
Salmonella typhimurium LT2
Gamma
AE006468
4527
32(29)
9(7)
1(1)
12(11)
15(11)
-
1(0)
-
-
63
53
84%
60
Erwinia carotovora
Gamma
BX950851
4472
28(23)
36(36)
2(1)
16*(11)
11(5)
-
1(0)
1(0)
-
92
74
80%
61
Shewanella oneidensis
Gamma
AE014299
4467
46(35)
26(24)
7(1)
52*(26)
27*(14)
9(1)
1(0)
1(0)
1(1)
148
90
61%
62
Shigella flexneri
Gamma
AE005674
4441
25(22)
4(4)
2(2)
8(6)
8(6)
-
1(0)
-
-
46
37
80%
63
Xanthomonas axonopodis
Gamma
AE008923
4427
61(38)
21(18)
10(3)
30(14)
14(5)
3(0)
-
-
1(1)
130
75
58%
64
Escherichia coli K12
Gamma
U00096
4242
30(27)
5(5)
2(2)
19(12)
17(11)
-
1(0)
-
-
67
52
78%
65
Xanthomonas campestris
Gamma
AE008922
4181
55(31)
20(16)
6(3)
31(15)
14(5)
3(0)
-
-
1(1)
120
67
56%
66
Salmonella enterica serovar Paratyphi
Gamma
CP000026
4093
26(24)
6(4)
1(1)
13(12)
15(11)
-
1(0)
-
-
55
46
84%
67
Yersinia pestis
Gamma
AL590842
4067
21(19)
6(4)
4(1)
5(5)
6(4)
-
1(0)
-
-
40
31
78%
68
Yersinia pseudotuberculosis
Gamma
BX936398
4038
26(25)
7(6)
4(1)
6(5)
6(4)
1(0)
1(0)
1(0)
-
49
38
78%
69
Vibrio cholerae 
Gamma
AE003852
3835
43(32)
45(37)
1(1)
41(27)
22(8)
9(2)
1(0)
-
-
152
100
66%
70
Acinetobacter sp. ADP1
Gamma
CR543861
3325
18(14)
-
6(1)
10(6)
4(1)
-
-
-
1(1)
36
22
61%
71
Methylococcus capsulatus
Gamma
AE017282
2959
17(14)
2(1)
3(2)
16(8)
12(5)
1(0)
-
-
-
40
26
65%
72
Legionella pneumophila
Gamma
AE017354
2942
12(7)
-
5(3)
19(11)
14(6)
-
-
-
5(4)
44
26
59%
73
Xylella fastidiosa 9a5c
Gamma
AE003849
2832
14(9)
1(1)
2(1)
3(1)
3(1)
1(0)
-
-
-
23
13
57%
74
Idiomarina loihiensis
Gamma
AE017340
2640
26(18)
15(13)
2(2)
33(17)
20(11)
1(0)
-
-
-
80
51
64%
75
Mannheimia succiniciproducens
Gamma
AE016827
2384
5(5)
-
1(0)
-
-
-
1(0)
-
-
7
5
71%
76
Coxiella burnetii
Gamma
AE016828
2046
7(2)
-
4(1)
0*
-
-
-
-
1(0)
12
3
25%
77
Pasteurella multocida 
Gamma
AE004439
2015
9(9)
-
1(1)
-
-
-
1(0)
-
-
11
10
91%
78
Francisella tularensis
Gamma
AJ749949
1804
2(2)
-
1(1)
-
-
-
-
-
-
3
3
100%
79
Haemophilus ducreyi
Gamma
AE017143
1717
1(1)
-
1(1)
-
-
-
1(0)
-
-
3
2
67%
80
Haemophilus influenzae
Gamma
L42023
1711
4(3)
-
1(0)
-
-
-
1(0)
-
-
6
3
50%
81
Wigglesworthia glossinidia
Gamma
BA000021
617
-
-
1(1)
-
-
-
-
-
-
1
1
100%
82
Candidatus Blochmannia floridanus
Gamma
BX248583
583
-
-
1(1)
-
-
-
-
-
-
1
1
100%
83
Buchnera aphidicola str. APS
Gamma
BA000003
574
-
-
-
-
-
-
-
-
-
-
-
nd
Delta-proteobacteria
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
84
Bdellovibrio bacteriovorus
Delta
BX842601
3587
49(30)
20(18)
5(1)
5(1)
1(0)
6(0)
-
-
4(4)
90
54
60%
85
Desulfovibrio vulgaris
Delta
AE017285
3531
64(36)
28(28)
1(0)
26(11)
10(3)
14(2)
-
1(0)
-
135
76
56%
86
Geobacter sulfurreducens
Delta
AE017180
3446
92(55)
33(30)
1(1)
28(13)
9(4)
10(0)
-
-
-
165
99
60%
87
Desulfotalea psychrophila
Delta
CR522870
3236
31(24)
21(20)
4(2)
23(12)
4(2)
10(5)
-
-
1(0)
91
58
64%
Epsilon-proteobacteria
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
88
Wolinella succinogenes
Epsilon
BX571656
2044
39(22)
31(27)
2(1)
21(10)
13*(5)
2(0)
-
-
1(1)
99
63
64%
89
Helicobacter hepaticus
Epsilon
AE017125
1875
5(3)
9(8)
-
1(0)
-
-
-
-
-
15
11
73%
90
Campylobacter jejuni
Epsilon
AL111168
1634
7(4)
10(6)
-
1(0)
-
-
-
-
-
18
10
56%
91
Helicobacter pylori
Epsilon
AE000511
1576
4(1)
4(3)
1(0)
-
-
-
-
-
-
9
4
44%
Firmicutes
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
92
Bacillus anthracis str. Ames
Firmi
AE016879
5311
47(43)
13(11)
5(2)
9*(6)
7(4)
1(1)
-
-
-
76
62
82%
93
Bacillus cereus ATCC 14579
Firmi
AE016877
5255
48(46)
13(11)
5(3)
7*(4)
5(2)
-
-
-
-
74
64
86%
94
Bacillus thuringiensis
Firmi
AE017355
5117
58(50)
12(10)
4(2)
9*(6)
7(4)
1(1)
-
-
-
85
68
80%
95
Bacillus licheniformis
Firmi
AE017333
4196
36(27)
11*(9)
3(1)
4*(3)
2(0)
-
-
-
-
56
40
71%
96
Bacillus subtilis
Firmi
AL009126
4105
36(30)
10(8)
4(3)
4*(3)
3(1)
-
-
-
-
56
44
79%
97
Bacillus halodurans
Firmi
BA000004
4066
44(36)
12(10)
4(3)
4*(1)
2(0)
2(0)
-
-
-
67
50
75%
98
Clostridium acetobutylicum
Firmi
AE001437
3848
37(32)
38*(30)
5(3)
10*(7)
4(1)
9(1)
-
1(0)
-
101
72
71%
99
Geobacillus kaustophilus
Firmi
BA000043
3540
26*(18)
6(5)
5(4)
8*(4)
5(2)
3(1)
-
-
-
50
32
64%
100
Oceanobacillus iheyensis
Firmi
BA000028
3500
19(16)
8(6)
4(3)
3*(1)
2(0)
2(0)
-
-
-
37
26
70%
101
Enterococcus faecalis
Firmi
AE016830
3267
16(15)
-
1(1)
0*
-
-
-
-
-
17
16
94%
102
Lactobacillus plantarum
Firmi
AL935263
3059
14(13)
-
3(3)
3*(3)
5(1)
-
-
-
-
25
20
80%
103
Listeria innocua
Firmi
AL592022
2968
15(13)
2(1)
2(2)
3*(3)
3(0)
-
-
-
-
25
19
76%
104
Listeria monocytogenes
Firmi
AL591824
2846
15(13)
2(1)
2(2)
3*(3)
3(0)
-
-
-
-
25
19
76%
105
Clostridium perfringens
Firmi
BA000016
2723
27(24)
-
3(2)
6*(4)
3(2)
1(1)
-
1(0)
-
40
31
76%
106
Staphylococcus aureus N315
Firmi
BA000018
2624
17(15)
-
2(1)
1*(1)
-
-
-
-
-
20
17
85%
107
Thermoanaerobacter tengcongensis
Firmi
AE008691
2588
17(12)
9(7)
3(3)
6*(1)
1(0)
6(0)
-
-
-
41
23
56%
108
Staphylococcus epidermidis
Firmi
AE015929
2419
15(13)
-
2(1)
1*(1)
-
-
-
-
-
18
15
83%
109
Clostridium tetani
Firmi
AE015927
2373
31(24)
20(16)
1(1)
6*(4)
1(0)
1(0)
-
1(0)
-
61
45
74%
110
Lactococcus lactis
Firmi
AE005176
2321
7(7)
-
1(1)
0*
-
-
-
-
-
8
8
100%
111
Streptococcus agalactiae
Firmi
AE009948
2124
18(18)
-
1(1)
0*
-
-
-
-
-
19
19
100%
112
Streptococcus pneumoniae TIGR4
Firmi
AE005672
2094
13(13)
-
4(1)
0*
-
-
-
-
-
17
14
82%
113
Streptococcus mutans
Firmi
AE014133
1960
14(13)
-
1(0)
0*
-
-
-
-
-
15
13
87%
114
Streptococcus thermophilus
Firmi
CP000024
1915
9*(8)
-
4(2)
0*
-
-
-
-
-
13
10
77%
115
Lactobacillus johnsonii
Firmi
AE017198
1821
9(9)
-
1(1)
0*
-
-
-
-
-
10
10
100%
116
Streptococcus pyogenes M1 GAS
Firmi
AE004092
1697
12(12)
-
1(1)
0*
-
-
-
-
-
13
13
100%
117
Mycoplasma penetrans
Firmi
BA000026
1037
-
-
2(1)
-
-
-
-
-
-
2
1
50%
118
Mycoplasma mycoides
Firmi
BX293980
1016
-
-
1(1)
-
-
-
-
-
-
1
1
100%
119
Mycoplasma pulmonis
Firmi
AL445566
782
-
-
1(1)
0*
-
-
-
-
-
1
1
100%
120
Onion yellows phytoplasma
Firmi
AP006628
754
-
-
-
0*
-
-
-
-
-
-
-
nd
121
Mycoplasma gallisepticum
Firmi
AE015450
726
-
-
1(1)
-
-
-
-
-
-
1
1
100%
122
Mycoplasma hyopneumoniae
Firmi
AE017332
691
-
-
-
0*
-
-
-
-
-
-
-
nd
123
Mycoplasma pneumoniae
Firmi
U00089
689
-
-
1(1)
-
-
-
-
-
-
1
1
100%
124
Mesoplasma florum
Firmi
AE017263
682
-
-
1(1)
-
-
-
-
-
-
1
1
100%
125
Mycoplasma mobile
Firmi
AE017308
633
-
-
2(1)
0*
-
-
-
-
-
2
1
50%
126
Ureaplasma parvum
Firmi
AF222894
614
-
-
1(1)
-
-
-
-
-
-
1
1
100%
127
Mycoplasma genitalium
Firmi
L43967
484
-
-
1(1)
-
-
-
-
-
-
1
1
100%
Other bacterial phyla
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
128
Rhodopirellula baltica 
Other
BX119912
7325
46*(22)
-
60(38)
9*(2)
3(0)
6(0)
-
1(0)
3(2)
126
64
51%
129
Bacteroides thetaiotaomicron
Other
AE015928
4778
85(73)
-
2(2)
-
-
-
-
-
-
87
75
86%
130
Bacteroides fragilis
Other
AP006841
4625
60(47)
-
-
-
-
-
-
-
-
60
47
78%
131
Deinococcus radiodurans
Other
AE000513
3184
21(12)
3(3)
9*(2)
16(7)
5(0)
4(0)
-
-
-
54
24
44%
132
Chlorobium tepidum
Other
AE006470
2252
8(2)
-
-
1(1)
-
-
-
-
1(0)
10
3
30%
133
Thermus thermophilus 
Other
AE017221
2210
11(8)
-
4(1)
6*(5)
2(0)
5(0)
-
-
1(0)
28
14
57%
134
Fusobacterium nucleatum 
Other
AE009951
2066
7(6)
-
-
-
-
-
-
-
1(0)
8
6
75%
135
Parachlamydia sp. UWE25
Other
BX908798
2031
2(1)
-
4(0)
-
-
-
-
-
-
6
1
17%
136
Porphyromonas gingivalis
Other
AE015924
1909
6(6)
-
-
-
-
-
-
-
-
6
6
100%
137
Thermotoga maritima
Other
AE000512
1858
8(4)
7(6)
-
9*(4)
-
10(2)
-
-
-
34
16
47%
138
Aquifex aeolicus
Other
AE000657
1560
4(2)
-
2(0)
11*(4)
6*(1)
1(0)
-
-
-
20
6
30%
139
Chlamydophila pneumoniae CWL029
Other
AE001363
1054
1(0)
-
3(0)
-
-
-
-
-
-
4
-
0%
140
Chlamydophila caviae
Other
AE015925
1005
1(0)
-
3(0)
-
-
-
-
-
-
4
-
0%
141
Chlamydia muridarum
Other
AE002160
904
1(0)
-
3(0)
-
-
-
-
-
-
4
-
0%
142
Chlamydia trachomatis
Other
AE001273
895
1(0)
-
3(0)
-
-
-
-
-
-
4
-
0%
Spirochaetes
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
143
Leptospira interrogans
Spiro
AE010300
4727
47(20)
13(13)
5(2)
16(3)
8(0)
2(0)
-
-
18(12)
107
50
47%
144
Treponema denticola 
Spiro
AE017226
2767
7(3)
20(19)
-
9(4)
2(2)
4(0)
-
-
9(7)
49
33
67%
145
Borrelia burgdorferi
Spiro
AE001115
1639
4(1)
5(4)
-
1(0)
1(0)
1(0)
-
1(0)
-
13
5
39%
146
Treponema pallidum 
Spiro
AE000520
1036
1(0)
4(4)
-
1*(0)
-
3(0)
-
-
1(1)
10
5
50%
147
Borrelia garinii
Spiro
CP000013
932
4(1)
5(4)
-
1(0)
1(0)
1(0)
-
1(0)
-
13
5
39%
Archaea
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM
148
Methanosarcina acetivorans
Archaea
AE010299
4540
53(11)
2(1)
5(2)
-
-
-
-
1(0)
-
61
14
23%
149
Haloarcula marismortui
Archaea
AY596297
4240
59(15)
17(9)
8(3)
-
-
-
-
1(0)
-
85
27
32%
150
Methanosarcina mazei
Archaea
AE008384
3371
33(9)
3(1)
4(1)
-
-
-
-
1(0)
-
41
11
28%
151
Sulfolobus solfataricus
Archaea
AE006641
2977
-
-
8(3)
-
-
-
-
1(0)
-
9
3
38%
152
Sulfolobus tokodaii
Archaea
BA000023
2825
-
-
12(6)
-
-
-
-
1(0)
-
13
6
50%
153
Halobacterium salinarum
Archaea
AE004437
2622
13(4)
17(12)
5(1)
-
-
-
-
1(0)
-
36
17
49%
154
Pyrobaculum aerophilum
Archaea
AE009441
2605
-
-
5(1)
-
-
-
-
1(0)
-
6
1
20%
155
Archaeoglobus fulgidus
Archaea
AE000782
2420
14*(3)
2(0)
3(0)
-
-
-
-
1(0)
-
20
3
16%
156
Pyrococcus furiosus
Archaea
AE009950
2125
-
-
5(0)
-
-
-
-
2(0)
-
7
-
0%
157
Pyrococcus horikoshii
Archaea
BA000001
1955
1(0)
5(3)
4(0)
-
-
-
-
2(0)
-
12
3
30%
158
Pyrococcus abyssi
Archaea
AL096836
1896
1(0)
5(3)
4(0)
-
-
-
-
2(0)
-
12
3
30%
159
Methanothermobacter thermautotrophicus
Archaea
AE000666
1873
16(8)
-
3(1)
-
-
-
-
1(0)
-
20
9
47%
160
Aeropyrum pernix
Archaea
BA000002
1841
-
-
4(1)
0*
-
-
-
1(0)
-
5
1
25%
161
Methanocaldococcus jannaschii
Archaea
L77117
1786
-
-
3(0)
-
-
-
-
1(0)
-
4
-
0%
162
Methanococcus maripaludis
Archaea
BX950229
1722
3(2)
4(4)
4(0)
-
-
-
-
1(0)
-
12
6
55%
163
Methanopyrus kandleri
Archaea
AE009439
1687
-
-
5(0)
0*
-
-
-
1(0)
-
6
-
0%
164
Picrophilus torridus
Archaea
AE017261
1535
-
-
5(2)
-
-
-
-
-
-
5
2
40%
165
Thermoplasma volcanium
Archaea
BA000011
1499
-
-
4(2)
-
-
-
-
-
-
4
2
50%
166
Thermoplasma acidophilum
Archaea
AL139299
1481
-
-
4(2)
-
-
-
-
-
-
4
2
50%
167
Nanoarchaeum equitans
Archaea
AE017199
535
-
-
3(0)
-
-
-
-
-
-
3
-
0%
No.
Organism name
Phylum
GenBank
Proteins
HisKin
MCP
STYK
GGDEF
EAL
HD-GYP
AC1
AC2
AC3
Total
TM
%TM

a Within each group, the organisms are sorted by the total number of encoded proteins. The numbers in bold indicate the total number of proteins of each kind, the numbers in parentheses - the ones with at least one predicted transmembrane segment. The numbers in the table are linked to protein lists, which are further linked to RefSeq and UniProt entries, BLink outputs, and CDD and Pfam domain architectures. Numbers with asterisks indicate the presence of proteins with highly divergent or truncated domains, not included in the total count but listed at the end of the each protein list. The numbers in the 'Total' column may be smaller than the sum of all types of proteins, as GGDEF and EAL domains are often fused on a single polypeptide chain.