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CSF oligoclonal banding - series: Procedure, part 3
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Both the samples are added to a gel, which is then filtered through a cartridge. The gel separates the proteins in each sample and the lab looks for oligoclonal banding.
Results:
Normal:
One or less bandings found in the CSF is normal.
Abnormal:
Results are considered abnormal if there are 2 or more bandings found in the CSF and not in the blood serum. This may indicate multiple sclerosis (MS). CSF oligoclonal bands are found in 83% to 94% of patients with definite MS. Other causes of oligoclonal banding in CSF include encephalitis, meningitis, Guillain-Barré syndrome, polyneuritis, headache, and other conditions.
Update Date: 4/30/2007 Updated by: Joseph V. Campellone, M.D., Division of Neurology, Cooper University Hospital, Camden, NJ. Review provided by VeriMed Healthcare Network.
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