Aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1)

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UGID:675419 UniGene Hs.460260 Homo sapiens (human) AKR1C1

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Aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001345.1	aldo-keto reductase family 1, member C2	H. sapiens	100.0	322
NP_085114.1	aldo-keto reductase family 1, member C6	M. musculus	84.5	322
NP_001079568.1	similar to hydroxysteroid (17-beta) dehydrogenase 5	X. laevis	73.6	321
NP_001070715.1	hypothetical protein LOC553452	D. rerio	57.1	314
NP_648484.1	CG6084 CG6084-PA, isoform A	D. melanogaster	55.1	313
NP_181315.2	aldo/keto reductase family protein	A. thaliana	51.4	292
NP_496925.1	hypothetical protein Y39G8B.1	C. elegans	45.4	314

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	liver; mouth; lung; brain; mixed; trachea; ascites; testis; cervix; thyroid; ovary; muscle; skin; stomach; larynx; esophagus; intestine; bladder; pharynx; vascular; adrenal gland; pancreas; kidney; connective tissue; eye; uncharacterized tissue; embryonic tissue; salivary gland; adipose tissue; heart; blood; thymus; nerve; uterus; mammary gland; spinal cord; pituitary gland; bone

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	10
Map position:	10p15-p14
UniSTS entry:	Chr 10	RH11162
UniSTS entry:		SHGC-12403
UniSTS entry:	Chr 10	STS-R98791
UniSTS entry:	Chr 10	SHGC-100143
UniSTS entry:	Chr 10	STS-U05861
UniSTS entry:	Chr 10	RH92273
UniSTS entry:	Chr 10	RH1568

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AB021654.1	Homo sapiens mRNA for DD2/bile acid-binding protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type 3, complete cds	P
BT007197.1	Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) mRNA, complete cds	P
BT006653.1	Homo sapiens aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) mRNA, complete cds	P
NM_001353.5	Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1), mRNA	P
AB031083.1	Homo sapiens mRNA for 20 alpha-hydroxysteroid dehydrogenase, complete cds	P
AB031084.1	Homo sapiens mRNA for bile acid-binding protein, complete cds	P
CR611068.1	full-length cDNA clone CS0DN004YP03 of Adult brain of Homo sapiens (human)	P
U05684.1	Homo sapiens dihydrodiol dehydrogenase mRNA, complete cds	PA
AK226067.1	Homo sapiens mRNA for aldo-keto reductase family 1, member C1 variant, clone: fk04082	A
M86609.1	Homo sapiens dihydrodiol dehydrogenase mRNA, complete cds	P
BC015490.2	Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase), mRNA (cDNA clone MGC:8954 IMAGE:3877178), complete cds	PA
BC014579.1	Homo sapiens cDNA clone IMAGE:3681106, partial cds	A
BC020216.1	Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase), mRNA (cDNA clone MGC:31890 IMAGE:4662654), complete cds	PA
AK310658.1	Homo sapiens cDNA, FLJ17700	P
AK303435.1	Homo sapiens cDNA FLJ60052 complete cds, highly similar to Aldo-keto reductase family 1 member C1 (EC1.1.1.-)	P
S68290.1	chlordecone reductase homolog {clone HAKRc} [human, liver, mRNA, 1158 nt]	P
D26124.1	Homo sapiens mRNA for dihydrodiol dehydrogenase isoform DD1, partial cds	P
BC040210.1	Homo sapiens aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase), mRNA (cDNA clone MGC:42600 IMAGE:4825338), complete cds	PA

EST sequences (10 of 887) [Show all sequences]

AA962456.1	Clone IMAGE:1553575	kidney	3' read	PA
BX106706.1	Clone IMAGp998D20664_;_IMAGE:297187	mixed
AI203621.1	Clone IMAGE:1744844	lung	3' read	PA
CB157186.1	Clone L17N670205n1-7-D05	liver	5' read	P
CB163887.1	Clone L17N670205n1-52-A03	liver	5' read	P
CB158546.1	Clone L18POOL1n1-11-E07	liver	5' read	P
CB159474.1	Clone L18POOL1n1-39-B03	liver	5' read	P
CB158428.1	Clone L19N779227-1-A09	liver	5' read	P
CB106385.1	Clone L3SNU475-3-E12	liver	5' read	P
CB106407.1	Clone L3SNU475-3-H05	liver	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria