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Index of Cleared Science Reviews
Index for Bladex (Pc Code 100101)
March 17, 1971. Memorandum. 3 Pages.
G.E. Whitmore. FDA.
Bladex (SD 15418) on corn (sweet corn kernels, corn grain
popcorn, forage and straw) 0.1 ppm
PESTICIDE PETITION NO. OFO-998
Tox review 000811.
December 6, 1977. Review. 12 Pages.
Ronald Ney. Efficacy and Ecological Effects Branch.
EUP for Corn, Alone and in Combination with Bladex, Banvel,
AAtrex, Paraquat and Roundup.
January 31, 1978. Memorandum. 4 Pages.
S-L Chan. Toxicology Branch.
EPA #100-EUP-59, An EUP for Dual 8E and Tank Mixes.
Inert ingredient information on page 1 is not included.
February 9, 1978. Memorandum. 2 Pages.
Larry Anderson. Toxicology Branch.
EPA (HED) Review of IBT Validation Report.
April 4, 1978. Memorandum. 4 Pages.
Carlos Rodriguez. Registration Division (Toxicology).
Request for Experimental Use Permit to Ship and Use a
Pesticide for Experimental Purpose Only. Bladex/Atrazine
(2:1) 4 Herbicide for Preemergence Application for the
Control of Weeds in Field Corn. EPA File Symbol 201-EUP-61.
Caswell #188C and 63.
May 18, 1978. Memorandum. 9 Pages.
Krystyna Locke. Toxicology Branch.
Bladex/Atrazine (2:1) 80W Herbicide. Caswell Nos. 63, 188C.
EPA Reg. No. 201-403 UNG.
February 4, 1980. Memorandum. 1 Page.
Larry Anderson. Toxicology Branch.
Validation Review of IBT Study No. J-238 Teratogenic Study
with Bladex in Albino Rabbits.
July 17, 1981. Memorandum. 7 Pages.
N. Platonow. Government of Canada.
Audit and Validation of the IBT Study: Teratogenic Study
with SD-15418 Bladex Technical in Albino Rabbits.
October 14, 1981. Memorandum. 3 Pages.
William Dykstra. Toxicology Branch.
EPA Reg. No. 201-279; 201-281; Bladex Teratology Study.
PP #9F2232 - Petition Proposing a Tolerance of 0.1 ppm...
Be Established to Cover Negligible Residues in or on
Soybeans. Accession No. 243335.
February 3, 1982. Memorandum. 5 Pages.
William Dykstra. Toxicology Branch.
EPA Reg. No. 201-279; 201-281; Bladex Rat Teratology
Study. PP #9F2232 - Petition Proposing a Tolerance of
0.1 ppm... Be Established to Cover Negligible Residues in
or on Soybeans.
May 23, 1982. Memorandum. 3 Pages.
William Dykstra. Toxicology Branch.
Bladex; PP#9F2232; Bladex in/on Soybeans; 2-Year Mouse
Oncogenicity Study
Accession Nos: 247295-298
Tox review 001884.
August 17, 1982. Memorandum. 2 Pages.
William Dykstra. Toxicology Branch.
Bladex; EPA Reg. No. 201-279, 201-281; PP # 9F2232;
Bladex in/on Soybeans.
January 26, 1983. Memorandum. 8 Pages.
William Dykstra. Toxicology Branch.
EPA Reg. No. 201-279; 201-281; Bladex - Addendum to Rat
Teratology Study. PP #9F2232 Petition Proposing a Tolerance
of 0.1 ppm... Be Established in or on Soybeans. Accession
No. 071285.
April 29, 1983. Memorandum. 14 Pages.
Amal Mahfouz. Toxicology Branch.
Bladex; EPA Reg. No. 201-279 and 201-281. A New Teratology
Study in Rabbits; PP #9F2232; Petition Proposing a
Tolerance of 0.1 ppm in/on Soybeans.
November 4, 1983. Memorandum. 2 Pages.
Amal Mahfouz. Toxicology Branch.
Bladex Teratology Study in F344 Rats.
November 14, 1983. Memorandum. 19 Pages.
Amal Mahfouz. Toxicology Branch.
PP #9F2239; Bladex in/on Soybeans; EPA Reg. No. 201-279
and 201-281. A New Teratology Study in SD CD Rats,
Accession No. 071738; and an Addendum to the Teratology
Study in F344 Rats, Accession No. 071739.
November 21, 1983. Memorandum. 4 Pages.
Amal Mahfouz. Toxicology Branch.
PP # 9F2232; Bladex/Soybeans; EPA Reg. No. 201-279 and
201-281. Historical Data for the Teratology Study in the
New Zealand Strain of Rabbits.
November 4, 1984. Memorandum. 5 Pages.
Quang Bui. Toxicology Branch.
Evaluation of additional data pertaining to the
teratology study with Bladex in SD-CD Rats.
PP#9F2232; Accession # 072838
Tox review 004077.
January 10, 1985. Memorandum. 26 Pages.
Christine Chaisson. Toxicology Branch.
EPA Reg. No. 201-298; Cyanazine (Bladex):
Oncogenicity in Rats.
Acc. No. 251954, 251955, 251956; 251949, 251950, 251951,
251952, 251953.
Tox review 004221.
May 29, 1985. Memorandum. 20 Pages.
Quang Bui. Toxicology Branch.
Review of Pilot Teratology Study with Bladex (Cyanazine) in
Fischer 344 and Sprague Dawley Rats. EPA Reg. No. 201-298.
EPA Accession Nos. 256693 Through 256696. Pages 9-20 are
not included - registrant submission.
June 5, 1985. Memorandum. 1 Page.
Quang Bui. Toxicology Branch.
Review of a Developmental Toxicology Study and a Subchronic
Study with Bladex (Cyanazine). EPA Reg. No. 201-298.
EPA Accession No. 257867 and 257868.
June 5, 1985. Memorandum. 6 Pages.
Quang Bui. Toxicology Branch.
Overview of the Teratogenic Potential of Bladex (Cyanazine).
June 5, 1985. Memorandum. 31 Pages.
Quang Bui. Toxicology Branch.
Review of a Developmental Toxicology Study and a Subchronic
Study with Bladex (Cyanazine). EPA Reg. No. 201-298.
EPA Accession No. 257867 and 257868. Pages 25-31 are not
included - registrant submission.
June 27, 1985. Memorandum. 1 Page.
Robert Zendzian. Toxicology Branch.
Bladex, 21-Day Dermal Study in Rabbits and Teratology Study
in Rats. Action Returned Studies Previously Reviewed by
Dr. Bui.
April 23, 1986. Memorandum. 39 Pages.
Quang Bui. Toxicology Branch.
Review of Toxicology Data of Bladex (Cyanazine). EPA No.
100-101. EPA No. 201-298. Project Nos. 1096 and 1596.
Pages 20-27 and 33-39 are not included - registrant
submissions.
August 6, 1986. Memorandum. 20 Pages.
Quang Bui. Toxicology Branch.
Expedite review of a dermal developement toxicology study
with Bladex 4L in rabbits. EPA No. 201-208 Project No.2116
Caswell No.1660
Pages 11-20 removed, registration data.
Tox. Review 005331.
March 18, 1987. Review. 27 Pages.
Emil Regelman. Exposure Assessment Branch.
Reg. No. 201-298. Bladex.
Partial Response to Groundwater Data Call-In. Hydrolysis,
Aerobic and Anaerobic Soil Metabolism and Leaching Data.
June 19, 1987. Memorandum. 5 Pages.
Theodore Farber. Toxicology Branch.
Peer Review Committee on Cyanazine (Bladex)
Tox review 008049.
June 23, 1987. Review. 7 Pages.
Carolyn Offutt. Exposure Assessment Branch.
Reg. No. 352-475. Bladex. Review of Ground Water
Monitoring Study.
October 7, 1987. Memorandum. 26 Pages.
Stephen Dapson. Toxicology Branch.
Review of a one-year chronic dog study with Cyanazine
and amendment to the final report.
EPA ID # 352-475, EPA Accession #'s 400819-01 and
402290-01; Pages 7-8, 16-26 removed, registration data.
Tox review 006350.
February 16, 1988. Memorandum. 32 Pages.
Sidney Stoltzenberg. Toxicology Branch.
Review of a Two-Generation Reproduction Study of
Technical Bladex (Cyanazine) in Rats (Sprague-Dawley)
325-475
Acc. 403600-01
Tox review 006597.
March 9, 1990. Memorandum. 36 Pages.
Stephen Dapson. Toxicology Branch.
Review additional data submitted in support of a
multigeneration study in rats with Bladex...
MRID 411111-01
Tox review 007804.
April 30, 1990. Memorandum. 58 Pages.
Irvin Mauer. Toxicology Branch.
Cyranazine - Mutagenicity Data Submitted under MRID
Nos. 00165051, 408045-02, -03, -04, and -05.
Pages 10-11, 18-22, 28-37, 43-49 and 56-58 removed,
registration data.
Tox review 007893.
March 6, 1991. Memorandum. 88 Pages.
Roger Gardner. Toxicology Branch I.
Cyanazine - EPA Registration No. 352-475 - 6(a)(2)
Data - 2-Year Chronic Toxicity/Oncogenicity Rat
Study with Cyanazine Technical - Reregistration and
Special Review Branchs' Referral.
Tox review 008280. Pgs 29-35, 52-88 removed, registrant data.
March 7, 1991. Memorandum. 78 Pages.
Ester Rinde. Health Effects Division.
Peer review of Cyanazine.
April 19, 1991. Memorandum. 15 Pages.
Ester Rinde. Science Analysis & Coordination Branch.
Health Effects Division (HED) Peer Review Committee
Draft Document on CYANAZINE.
May 13, 1991. Memorandum. 1 Page.
Bernice Fisher. Science Analysis & Coordination Branch.
Cyanazine (188C), Atrazine (63) and Simazine (740)
Quantitative Risk Assessment Comparisons on Malignant
Mammary Gland Tumors only in Rats.
July 8, 1991. Memorandum. 2 Pages.
Bernice Fisher. Science Analysis & Coordination Branch.
Cyanazine (188C), Atrazine (63) and Simazine (740)
Quantitative Risk Assessment Comparisons on Malignant
Mammary Gland Tumors only in Rats. Revised Comparisons
as of July, 1991.
July 30, 1991. Memorandum. 17 Pages.
William Dykstra. Toxicology Branch.
Peer review of Cyanazine (Bladex).
August 20, 1991. Memorandum. 74 Pages.
William Dykstra. Toxicology Branch I.
Peer Review of Cyanazine (Bladex)
Tox review 008521
Pages 68-74 are not included-registrant data.
March 11, 1992. Memorandum. 2 Pages.
Roger Gardner. Toxicology Branch 1.
Cyanazine; Historical Control Data on 2-Year Rat Study;
ID # 100101; Support of Reregistration
Tox review 009353.
August 3, 1992. Memorandum. 6 Pages.
George Ghali. Toxicology Branch.
Cyanazine: Report of the RfD/Peer Review.
August 7, 1992. Memorandum. 3 Pages.
Michael S. Metzger. Chemistry Branch II.
Atrazine,Simazine, & Cyanazine. Results of the Metabolism
Committee Meeting of 07/09/92.
August 7, 1992. Memorandum. 3 Pages.
Michael S. Metzger. Chemistry Branch II.
Atrazine,Simazine, & Cyanazine. Results of the Metabolism
Committee Meeting of 07/09/92.
November 13, 1992. Memorandum. 15 Pages.
Stephen Schaible. Science Analysis Branch.
Dietary Exposure Analysis and Carcinogenic Risk Assessment
for Cyanazine and Metabolites Using Anticipated Residues.
June 14, 1993. Memorandum. 2 Pages.
Reto Engler. Health Effects Division.
Cyanazine; Quantitative Estimate of Carcinogenic Risk:
Oral Slope Factor.
July 13, 1993. Memorandum. 25 Pages.
William Dykstra. Toxicology Branch.
Cyanazine: Reregistration Case; 0066; ID# 100101; Review of
New Toxicology Studies Submitted in Support of
Reregistration.
MRID 427395-01, -02, -03, -04.
Tox review 010382.
March 7, 1994. Memorandum. 27 Pages.
Michael Beringer. Chemical Coordination Branch.
Revised Occupational and residential Risk Assessment
for the Triazines
(see the atrazine cleared science review file for this doc.).
August 7, 1995. Memorandum. 4 Pages.
George Keit. Biological Analysis Branch.
Response to Ciba-Geigy Regarding Triazine Benefits Analysis.