STUDIES ON DESTRUCTION OF RED BLOOD CELLS. II. CHRONIC HEMOLYTIC ANEMIA WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA: CERTAIN IMMUNOLOGICAL ASPECTS OF THE HEMOLYTIC MECHANISM WITH SPECIAL REFERENCE TO SERUM COMPLEMENT

doi:10.1172/JCI101081

J Clin Invest. 1939 November; 18(6): 657–672.

doi: 10.1172/JCI101081.

PMCID: PMC434913

STUDIES ON DESTRUCTION OF RED BLOOD CELLS. II. CHRONIC HEMOLYTIC ANEMIA WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA: CERTAIN IMMUNOLOGICAL ASPECTS OF THE HEMOLYTIC MECHANISM WITH SPECIAL REFERENCE TO SERUM COMPLEMENT ¹

Thomas Hale Ham and John H. Dingle²

Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard) Boston City Hospital, Boston

Department of Medicine, Harvard Medical School, Boston

Department of Bacteriology and Immunology, Harvard Medical School, Boston

² This work was done during the tenure of the James Jackson Cabot and DeLamar Fellowships.

¹ The investigation was aided in part by a grant from the Penrose Fund of the American Philosophical Society.

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