A Spinal fMRI Study of Resting-State, Motor Task and Acupoint Stimulation

This study is currently recruiting participants.

Verified by China Rehabilitation Research Center, February 2008

First Received: February 27, 2008 Last Updated: July 23, 2008 History of Changes

Sponsors and Collaborators:	China Rehabilitation Research Center Ministry of Finance,China Capital Medical University
Information provided by:	China Rehabilitation Research Center
ClinicalTrials.gov Identifier:	NCT00629655

Purpose

The spinal cord is a very important part of the central nervous system. fMRI can be applied to observe functional status of the human spinal cord. Under different conditions, the investigators will see different types of fMRI signals within spinal cord. In resting state, the investigators might see active/deactive signals, too.

Condition	Intervention
Cerebral Infarction Healthy	Other: motor task, sensory stimulation

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cross-Sectional
Official Title:	A Spinal fMRI Study of Resting-State, Motor Task and Acupoint Stimulation

Further study details as provided by China Rehabilitation Research Center:

Primary Outcome Measures:

fMRI [ Time Frame: at once ] [ Designated as safety issue: No ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	20
Study Start Date:	February 2008
Estimated Study Completion Date:	December 2008
Estimated Primary Completion Date:	December 2008 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
1 healthy people, male	Other: motor task, sensory stimulation motor task: finger tapping, simple type and complex type sensory stimulation: electric or tactile stimulation
2 male patients with cerebral infarction, chronic stage	Other: motor task, sensory stimulation motor task: finger tapping, simple type and complex type sensory stimulation: electric or tactile stimulation

Eligibility

Ages Eligible for Study:	18 Years to 45 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

group 1: male residents of Beijing group 2: male stroke patients of Beijing Boai hospital

Criteria

Inclusion Criteria(for healthy people):

Chinese male residents
right handed
no history of psychological/psychotic problems
no history of important diseases

Exclusion Criteria(for healthy people):

with factors which make subjects unsuitable to receive MR examination
history of important diseases

Inclusion Criteria(for patients):

Chinese male patients with ischemic stroke (CT/MRI scan confirmed)
right handed
at least 1.5 months from onset of stroke
ability to follow complex commands

Exclusion Criteria(for patients):

hemodynamic instability
history of dementia
inability to give consent because of impaired cognition or receptive aphasia
diseases in spine/spinal cord
with factors which make subjects unsuitable to receive MR examination

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00629655

Contacts

Contact: Pengxu Wei, Master

86-10-87569308

pengxuwei@gmail.com

Locations

China
Beijing Boai Hospital	Recruiting
Beijing, China, 100068
Principal Investigator: Pengxu Wei, Master

Sponsors and Collaborators

China Rehabilitation Research Center

Ministry of Finance,China

Capital Medical University

Investigators

Principal Investigator:

Pengxu Wei, Master

China Rehabilitation Research Center

More Information

No publications provided

Responsible Party:	China Rehabilitation Research Center ( Pengxu Wei )
Study ID Numbers:	2007CZ-4
Study First Received:	February 27, 2008
Last Updated:	July 23, 2008
ClinicalTrials.gov Identifier:	NCT00629655 History of Changes
Health Authority:	China: Ministry of Health

Keywords provided by China Rehabilitation Research Center:

cerebral infarction
fMRI
health
human
spinal cord

Study placed in the following topic categories:

Necrosis
Cerebral Infarction
Stroke
Vascular Diseases
Central Nervous System Diseases
Brain Ischemia

Healthy
Ischemia
Brain Infarction
Brain Diseases
Infarction
Cerebrovascular Disorders

Additional relevant MeSH terms:

Cerebral Infarction
Stroke
Nervous System Diseases
Vascular Diseases
Central Nervous System Diseases
Ischemia
Brain Diseases

Cerebrovascular Disorders
Necrosis
Pathologic Processes
Brain Ischemia
Cardiovascular Diseases
Brain Infarction
Infarction

ClinicalTrials.gov processed this record on March 16, 2009