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| Reference: |
Jenni S, Leibundgut M, Boehringer D, Frick C, Mikolasek B, Ban NStructure of fungal fatty acid synthase and implications for iterative substrate shuttlingScience v316, p.254-261We report crystal structures of the 2.6-megadalton alpha6beta6 heterododecameric fatty acid synthase from Thermomyces lanuginosus at 3.1 angstrom resolution. The alpha and beta polypeptide chains form the six catalytic domains required for fatty acid synthesis and numerous expansion segments responsible for extensive intersubunit connections....
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| Description: |
Crystal Structure Of Fatty Acid Synthase Complexed With Nadp+ From Thermomyces Lanuginosus At 3.1 Angstrom Resolution. This File Contains The Beta Subunits Of The Fatty Acid Synthase. The Entire Crystal Structure Consists Of One Heterododecameric Fatty Acid Synthase And Is Described In Remark 400. |
| Deposition: |
2007/3/9   |
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| Author: |
Jenni S, Leibundgut M, Boehringer D, Frick C, Mikolasek B, Ban N |
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| Taxonomy: |
Thermomyces lanuginosus |
| Related Structure: |
VAST |
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Molecular components in the MMDB structure are listed below and may include macromolecular chains, 3D domains, protein classifications (domain families), and ligands, as available. Mouse over each icon for more information on the component.  | Ligand |
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FAD |
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6 occurrences |
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NADP |
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6 occurrences |
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Citing MMDB:
Wang Y, Addess KJ, Chen J, Geer LY, He J, He S, Lu S, Madej T, Marchler-Bauer A, Thiessen PA, Zhang N, Bryant SH.
"MMDB: annotating protein sequences with Entrez's 3D-structure database.",
Nucleic Acids Res. 2007 Jan; 35(Database issue): D298-300.
Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH.
"MMDB: Entrez's 3D-structure database", Nucleic Acids Res. 2003 Jan; 31(1): 474-7.
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