Hess EV, Solinger AM, Belhorn LR; International Conference on AIDS.
Int Conf AIDS. 1992 Jul 19-24; 8: 89 (abstract no. PuB 7243).
University of Cincinnati Medical Center, Ohio.
OBJECTIVES: To ascertain the incidence of rheumatic and autoimmune diseases in a prospective study of a large community HIV/AIDS clinic. METHODS: The AIDS Related Diseases (ARD) Clinic was established in 1986 and currently 1700 HIV positive and AIDS patients (Pts) are being followed at the clinic which is the primary care source for HIV positive Pts in a 24-county cachement area. The first 1,100 Pts were evaluated for the presence of recognized rheumatic and autoimmune diseases utilizing 1) a complete Pt questionnaire, chart review and evaluation of patients by a rheumatologist. All Pts had an autoimmune antibody profile. The standard incidence/prevalence data for rheumatic and autoimmune diseases in the United States was utilized to determine the expected number of Pts. RESULTS: Of the study group (93% males: 7% females; 86% Caucasians, 14% Blacks; 17% IV drug users; 5% hemophiliacs; 0.5% blood products exposure), 1 Pt had Reiter's syndrome (RS), 9 psoriasis with refractory skin disease of whom 4 had classic psoriatic arthritis, 3 temporal arteritis/polymyalgia rheumatica (TA/PR); 7 diffuse myalgias (5 AZT-related), 8 arthralgic syndromes. Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjogren's syndrome, DILS and ankylosing spondylitis (AS) were not seen. Evaluation of the more recently entered 600 Pts has contributed 5 more Pts with RS. CONCLUSIONS: This study showed a greater than expected incidence of Reiter's syndrome and an unexpected number with TA/PR (expected number, 0.05). Further studies of the demographics of patient populations, risk and ascertainment factors and differences in infection demographics are urgently required. Such a prospective study is underway at this ARD unit and it is suggested that far more attention should be paid to the possible association of these diseases with HIV and AIDS.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Arthritis, Psoriatic
- Arthritis, Reactive
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Female
- HIV Infections
- HIV Seropositivity
- Humans
- Incidence
- Lupus Erythematosus, Systemic
- Male
- Muscular Diseases
- Prevalence
- Prospective Studies
- Psoriasis
- Rheumatic Diseases
- Spondylitis, Ankylosing
- United States
Other ID:
UI: 102202239
From Meeting Abstracts