Gene name

sigG

Locus tag

Rv0182c

Gene type

protein coding

RefSeq status

Validated

Organism

Mycobacterium tuberculosis H37Rv (strain: H37Rv)

Lineage

Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex

Also known as

sigG

(minus strand) Go to reference sequence detailsTry our new Sequence Viewer

Related Articles in PubMed

GeneRIFs: Gene References Into FunctionWhat's a GeneRIF?

1.

A DeltasigG mutant was found to be more resistant to mitomycin C treatment than the wild-type strain, indicating that it may be involved in the SOS response in M. tuberculosis.

misc_feature

Loc: c213894-213856 PS01063 Sigma-70 factors ECF subfamily signature

Names

RNA polymerase factor sigma-70

NP_214696.1

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

EC 2.7.7.6

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

mRNA and Protein(s)

1. NP_214696.1 RNA polymerase factor sigma-70 [Mycobacterium tuberculosis H37Rv]

   UniProtKB/TrEMBL

   O07426

   Conserved Domains (4) summary

   cd06171
   Location:185–233
   Blast Score:117

   Sigma70_r4; Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial...

   PRK08241
   Location:29–370
   Blast Score:1304

   PRK08241; RNA polymerase factor sigma-70; Validated

   pfam04542
   Location:63–122
   Blast Score:165

   Sigma70_r2; Sigma-70 region 2

   cl09109
   Location:250–303
   Blast Score:95

   NTF2_like; Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...