Klug here replied to and extended Crick's evaluation of recent research in several laboratories on the structure, spacing, and folding of DNA and its associated proteins, the histones, on the chromosomes during cell division (mitosis). This research was designed to produce an understanding of how DNA is folded into the tight structure seen in a chromosome, how genes are separated by function, and how their expression is controlled.
Number of Image Pages:
2 (96,529 Bytes)
Date:
1977-10-31 (October 31, 1977)
Creator:
Klug, Aaron
Recipient:
Crick, Francis
Source:
Original Repository: Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers