LOCUS       NP_782513                456 aa            linear   BCT 20-JUL-2008
DEFINITION  tRNA (uracil-5-) -methyltransferase [Clostridium tetani E88].
ACCESSION   NP_782513
VERSION     NP_782513.1  GI:28211569
DBSOURCE    REFSEQ: accession NC_004557.1
KEYWORDS    .
SOURCE      Clostridium tetani E88
  ORGANISM  Clostridium tetani E88
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
REFERENCE   1  (residues 1 to 456)
  AUTHORS   Bruggemann,H., Baumer,S., Fricke,W.F., Wiezer,A., Liesegang,H.,
            Decker,I., Herzberg,C., Martinez-Arias,R., Merkl,R., Henne,A. and
            Gottschalk,G.
  TITLE     The genome sequence of Clostridium tetani, the causative agent of
            tetanus disease
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 100 (3), 1316-1321 (2003)
   PUBMED   12552129
REFERENCE   2  (residues 1 to 456)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2004) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 456)
  AUTHORS   Bruggemann,H., Baumer,S., Fricke,W.F., Wiezer,A., Liesegang,H.,
            Decker,I., Herzberg,C., Martinez-Arias,R., Merkl,R., Henne,A. and
            Gottschalk,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2002) Goettingen Genomics Laboratory, Institute
            of Microbiology and Genetics, Georg-August University,
            Grisebachstr. 8, Goettingen 37077, Germany
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AAO36450.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Clostridium tetani E88"
                     /strain="Massachusetts"
                     /sub_strain="E88"
                     /db_xref="taxon:212717"
     Protein         1..456
                     /product="tRNA (uracil-5-) -methyltransferase"
                     /EC_number="2.1.1.35"
                     /calculated_mol_wt=51418
     Region          6..59
                     /region_name="TRAM"
                     /note="TRAM domain; cl01282"
                     /db_xref="CDD:120537"
     Region          7..446
                     /region_name="TrmA"
                     /note="SAM-dependent methyltransferases related to tRNA
                     (uracil-5-)-methyltransferase [Translation, ribosomal
                     structure and biogenesis]; COG2265"
                     /db_xref="CDD:32446"
     Region          312..>391
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy)...; cd02440"
                     /db_xref="CDD:100107"
     Site            order(316..322,338..339,364..366,383)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site"
                     /db_xref="CDD:100107"
     CDS             1..456
                     /locus_tag="CTC01941"
                     /coded_by="complement(NC_004557.1:2063929..2065299)"
                     /transl_table=11
                     /db_xref="GeneID:1058721"
ORIGIN      
        1 mamrkgkeye lnieeiefps mgiayheglk vyvkhgipgq kvlarittkk kdhakgkiie
       61 vledlpykie akcpafgqcg gcahqdipye kqleikqhei lelfkkanld gfdflpiegs
      121 pkqyeyrnkm eftfgdlkkg gelnlgmhak gmsfgiisad eckivdedyr nilnatlnyf
      181 rekqlphyri maregylrnl virkaentge vlvnlvttsq idfnldeyte iiksinykgn
      241 lvgilhtind slsdvvqcdk lnilygrdyi iedllglkfk itplsffqtn skgaeklysi
      301 vrdfigesks ktvfdlycgt gtigqivape akkvigieli eeavesaren aklnnlnnce
      361 fiagdiaqvi kevkqkpdvi ildpprpgvh pkaleyvikf dsptivyvsc npktlvedlk
      421 vlvengyvie kvkgmdmfps tphvetvvgl rrkdtl
//