Calcium deposition as a cause of spoilation of hydrophilic soft contact lenses.

Br J Ophthalmol. 1975 March; 59(3): 141–148.

PMCID: PMC1017370

M. Ruben, R. C. Tripathi, and A. F. Winder

This article has been cited by other articles in PMC.

Abstract

A series of 75 spoilt soft lenses with opacities (mostly manifesting as discrete spots or as large areas of cloudiness, chalk-white in appearance) were subjected to histochemical, electron microscopical, electron probe x-ray microanalytical, x-ray diffraction, atomic absorption spectro-photometric, and biochemical analyses. The results showed that in many cases calcium was implicated in the deposit formation and that a broad correlation existed between the amount of calcium present and the degree of opacification. The possible mode of calcium deposition and resulting implications in lens intolerance are discussed. It is advocated that a search should be made for a modified or new soft lens material which does not permit calcium deposition, and that the medical practitioner should strive towards improved assessment of the systemic and ocular conditions which may help in identifying patients at risk of early lens failure.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (3.3M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Image
on p.141

Image
on p.142

Image
on p.144

Image
on p.145

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

Abrams, JD. Corneal and other ocular findings in patients on intermittent dialysis for renal failure. Proc R Soc Med. 1966 Jun;59(6):533–534. [PubMed]
Berlyne, GM. Microcrystalline conjunctival calcification in renal failure. A useful clinical sign. Lancet. 1968 Aug 17;2(7564):366–370. [PubMed]
Brown, SI; Bloomfield, S; Pearce, DB; Tragakis, M. Infections with the therapeutic soft lens. Arch Ophthalmol. 1974 Apr;91(4):275–277. [PubMed]
Dohlman, CH; Boruchoff, A; Mobilia, EF. Complications in use of soft contact lenses in corneal disease. Arch Ophthalmol. 1973 Nov;90(5):367–371. [PubMed]
Doughman, DJ; Ingram, MJ; Bourne, WM. Experimental band keratopathy electron microprobe x-ray analysis of aqueous and corneal calcium concentrations. Invest Ophthalmol. 1970 Jun;9(6):471–475. [PubMed]
Filppi, JA; Pfister, RM; Hill, RM. Penetration of hydrophilic contact lenses by Aspergillus fumagatus. Am J Optom Arch Am Acad Optom. 1973 Jul;50(7):553–557. [PubMed]
Fishman, RS; Sunderman, FW. Band keratopathy in gout. Arch Ophthalmol. 1966 Mar;75(3):367–369. [PubMed]
Harris, LS; Cohn, K; Toyofuku, H; Lonergan, E; Galin, MA. Conjunctival and corneal calcific deposits in uremic patients. Am J Ophthalmol. 1971 Jul 30;72(1):130–133. [PubMed]
HILL, JB. AUTOMATED FLUOROMETRIC METHOD FOR DETERMINATION OF SERUM CALCIUM. Clin Chem. 1965 Feb;11:122–130. [PubMed]
Matas, BR; Spencer, WH; Hayes, TL. Scanning electron microscopy of hydrophilic contact lenses. Arch Ophthalmol. 1972 Sep;88(3):287–295. [PubMed]
Sibley, MJ; Yung, G. A technique for the determination of chemical binding to soft contact lenses. Am J Optom Arch Am Acad Optom. 1973 Sep;50(9):710–714. [PubMed]
Tragakis, MP; Brown, SI; Pearce, DB. Bacteriologic studies of contamination associated with soft contact lenses. Am J Ophthalmol. 1973 Mar;75(3):496–499. [PubMed]