Testing Information

Testing Status of Agents at NTP

Benzo(f)-quinoline

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http://ntp.niehs.nih.gov/go/TS-11079-K

CASRN: 85-02-9

Formula: C13-H9-N

Synonyms/Common Names:

  • 5,6-BENZOQUINOLINE

Known Uses:

REAGENT FOR CADMIUM, OCCURS IN COAL TARS (H.B. OF P.A.H.)

Special Studies

  • Absorption Disposition Metabolism Elimination (Intravenous; Gavage)  (S0042) Completed 
    • Citation: DISPOSITION OF BENZO(f)QUINOLINE IN MALE RATS. DRUG METABOLISM AND DISPOSITION, VOL. 13, NO. 1. 18-24. 1985. L S BIRNBAUM AND L JOHNSON
    • M Rats: F344/N; M Rats: F344/N
    • Dose: PO:1,10,100 MG/KG

Genetic Toxicology

  • Salmonella  (403492) Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Inconclusive 
  • Salmonella  (934591) Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Positive