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UGID:159220     UniGene Hs.181272     Homo sapiens (human)   PKD2
Polycystic kidney disease 2 (autosomal dominant) (PKD2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_000288.1 polycystin 2 H. sapiens 100.0 967
NP_032887.2 polycystic kidney disease 2 M. musculus 93.0 965
NP_001002310.1 polycystic kidney disease 2 D. rerio 75.9 899
NP_609561.2 Polycystic kidney disease gene-2 CG6504-PA D. melanogaster 48.1 391

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; embryonic tissue; lung; pancreas; vascular; mixed; uncharacterized tissue; eye; muscle; pituitary gland; liver; placenta; kidney; mammary gland; stomach; testis; heart; umbilical cord; prostate; skin; larynx; mouth; thymus; bladder; tonsil; ear; ascites; ovary; bone; lymph node; connective tissue; amniotic fluid; parathyroid; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q21-q23
UniSTS entry: Chr 4 SHGC-67606
UniSTS entry: Chr 4 SHGC-67908
UniSTS entry: Chr 4 STS-R48232
UniSTS entry: SHGC-59817
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_000297.2 Homo sapiens polycystic kidney disease 2 (autosomal dominant) (PKD2), mRNA PA
BC112261.1 Homo sapiens polycystic kidney disease 2 (autosomal dominant), mRNA (cDNA clone MGC:138466 IMAGE:8327729), complete cds P
BC112263.1 Homo sapiens polycystic kidney disease 2 (autosomal dominant), mRNA (cDNA clone MGC:138468 IMAGE:8327731), complete cds P
U50928.1 Human autosomal dominant polycystic kidney disease type II (PKD2) mRNA, complete cds P
U56813.1 Human polycystwin mRNA, partial cds PA
AK294173.1 Homo sapiens cDNA FLJ50473 complete cds, highly similar to Polycystin-2 P
AK293461.1 Homo sapiens cDNA FLJ50446 complete cds, highly similar to Polycystin-2 P
AF113693.1 Homo sapiens clone FLB5135
AF054992.1 Homo sapiens clone 23778 autosomal dominant polycystic kidney disease type II protein mRNA, partial cds A

EST sequences (196)

AA987851.1 Clone IMAGE:1593958 kidney 3' read A
AI040853.1 Clone IMAGE:1647537 parathyroid 3' read P
AI078766.1 Clone IMAGE:1677193 mixed 3' read A
AI079447.1 Clone IMAGE:1680497 skin 3' read A
AI090067.1 Clone IMAGE:1697038 uterus 3' read A
AI091028.1 Clone IMAGE:1689731 mixed 3' read A
AI093570.1 Clone IMAGE:1696361 uterus 3' read A
AI146278.1 Clone IMAGE:1707063 heart 3' read
AI147616.1 Clone IMAGE:1696984 uterus 3' read A
AI148271.1 Clone IMAGE:1680571 skin 3' read A
AI192923.1 Clone IMAGE:1743697 lung 3' read A
AI192927.1 Clone IMAGE:1743705 lung 3' read A
AI214159.1 Clone IMAGE:1956901 brain 3' read P
AI266051.1 Clone IMAGE:1932277 mixed 3' read A
AI085614.1 Clone IMAGE:1678082 mixed 3' read A
AI312015.1 Clone IMAGE:1929114 lung 3' read A
R38199.1 Clone IMAGE:23778 brain 3' read A
AI347615.1 Clone IMAGE:1916665 kidney 3' read
AI349570.1 Clone IMAGE:1928645 lung 3' read A
AI371127.1 Clone IMAGE:2045574 lung 3' read A
AI375153.1 Clone IMAGE:2063406 mixed 3' read A
AI381696.1 Clone IMAGE:2089325 mixed 3' read A
R48231.1 Clone IMAGE:153473 mammary gland 5' read P
R48232.1 Clone IMAGE:153473 mammary gland 3' read
CB215087.1 Clone IMAGE:5936617 uterus 5' read
AI307223.1 Clone IMAGE:2054671 kidney 3' read
AI473603.1 Clone IMAGE:2144107 pancreas 3' read A
AI494003.1 Clone IMAGE:2042535 uterus 3' read A
AI621344.1 Clone IMAGE:2282108 uterus 3' read A
AI652012.1 Clone IMAGE:2309250 uncharacterized tissue 3' read A
AI745253.1 Clone IMAGE:2364732 mixed 3' read A
AI887723.1 Clone IMAGE:2436240 uterus 3' read
AI888840.1 Clone IMAGE:2447630 stomach 3' read A
AI638275.1 Clone IMAGE:2240567 uncharacterized tissue 3' read A
CB996964.1 Clone IMAGE:30332842 placenta 5' read
CD251213.1 Clone IMAGE:30385616 pituitary gland 5' read
CD251805.1 Clone IMAGE:30383294 testis 5' read P
AW001816.1 Clone IMAGE:2496299 kidney 3' read P
CD511594.1 Clone IMAGE:30405582 vascular 5' read
CD518730.1 Clone IMAGE:30396191 brain 5' read
AW027837.1 Clone IMAGE:2533986 stomach 3' read A
BX501309.1 Clone DKFZp779B2462 liver 5' read P
BX509749.1 Clone DKFZp686F1281 muscle 5' read
CD678618.1 Clone hp10g09 eye 5' read
CD679148.1 Clone hq05f09 eye 5' read
AW069616.1 Clone HBMSC_cr47g04 bone marrow 3' read A
AI114740.1 liver
CF552210.1 Clone IMAGE:30530495 muscle 5' read P
AW338910.1 Clone IMAGE:2878862 pancreas 3' read A
CK000264.1 Clone IMAGE:30706949 mixed 5' read
CK299918.1 Clone UI-E-EJ1-ajy-k-23-0-UI eye 3' read A
AW600307.1 Clone zc43 lung 3' read A
CK825790.1 Clone IMAGE:5782307 pancreas 3' read
CN268828.1 embryonic tissue 5' read
CN268829.1 embryonic tissue 5' read A
CN268830.1 embryonic tissue 5' read P
CN268831.1 embryonic tissue 5' read P
CN268832.1 embryonic tissue 5' read A
CN268833.1 embryonic tissue 5' read P
CN268834.1 embryonic tissue 5' read P
CN268835.1 embryonic tissue 5' read P
CN268826.1 embryonic tissue 5' read P
CN268827.1 embryonic tissue 5' read
CN268836.1 embryonic tissue 5' read P
CN268838.1 embryonic tissue 5' read
BE079852.1 mammary gland
BE095173.1 mammary gland P
BP240937.1 Clone HEP13476 liver 5' read
BP313475.1 Clone OFR03344 mammary gland 5' read P
BP345212.1 Clone SYN05191 connective tissue 5' read
BP372674.1 Clone UBA03412 umbilical cord 5' read
BP274661.1 Clone KDN01609 kidney 5' read P
BP292628.1 Clone LNG08207 lung 5' read
BP293369.1 Clone LNG11778 lung 5' read
BP293632.1 Clone LNG13339 lung 5' read
BP335757.1 Clone SMR03444 vascular 5' read P
BP337016.1 Clone SMR07277 vascular 5' read P
BP379405.1 Clone WMD05749 uterus 5' read
AV646886.1 Clone GLCASD03 liver 3' read P
BE645590.1 Clone IMAGE:3288043 prostate 3' read A
BE645879.1 Clone IMAGE:3288521 prostate 3' read A
CX786895.1 Clone IMAGE:7481810 embryonic tissue 5' read
R88111.1 Clone IMAGE:186824 mammary gland 5' read
BE813041.1 amniotic fluid
BE828265.1 lung
BE889865.1 Clone IMAGE:3913252 uterus 5' read P
DR005514.1 Clone TC110976 prostate 5' read P
BE905059.1 Clone IMAGE:3898869 pancreas 5' read P
BE970070.1 Clone IMAGE:3950468 pancreas 5' read P
DR156524.1 Clone IMAGE:7964937 embryonic tissue 5' read A
DR157532.1 Clone IMAGE:7966131 embryonic tissue 5' read P
BF088356.1 larynx
BF109649.1 Clone IMAGE:3526290 mixed 3' read
BF447971.1 Clone IMAGE:3135104 kidney 3' read P
DA274646.1 Clone BRCOC2001080 brain 5' read P
BF674401.1 Clone IMAGE:4273647 prostate 5' read
DA172126.1 Clone BRAMY2034540 brain 5' read P
DA180870.1 Clone BRAMY2045732 brain 5' read P
DA152893.1 Clone BRAMY2011250 brain 5' read
DA153606.1 Clone BRAMY2012135 brain 5' read P
DA155312.1 Clone BRAMY2014230 brain 5' read P
DA619172.1 Clone JCMLC1000170 uncharacterized tissue 5' read P
DA632833.1 Clone KIDNE2014467 kidney 5' read P
DA914626.1 Clone SKNSH2009211 brain 5' read P
DA766776.1 Clone NTONG2008099 mouth 5' read P
DA711991.1 Clone NT2RI2018044 5' read P
DA711992.1 Clone NT2RI2018045 5' read P
DA857855.1 Clone PLACE7009250 placenta 5' read P
BF512267.1 Clone IMAGE:3069259 uncharacterized tissue 3' read
BF512307.1 Clone IMAGE:3069439 uncharacterized tissue 3' read P
DB082772.1 Clone TESTI4029200 testis 5' read P
DB305409.1 Clone BRAWH3024831 brain 3' read
DB155227.1 Clone THYMU3033483 thymus 5' read
DB267346.1 Clone UTERU2027494 uterus 5' read
DB170950.1 Clone TKIDN2005675 kidney 5' read
DB282310.1 Clone UTERU3009511 uterus 5' read P
DB277865.1 Clone UTERU3003681 uterus 5' read P
DB290234.1 Clone UTERU3020185 uterus 5' read P
DB255570.1 Clone UTERU2010981 uterus 5' read
BF990640.1 placenta P
H97660.1 Clone IMAGE:251497 skin 3' read A
BF911403.1 uterus
BF911406.1 uterus
BG402881.1 Clone IMAGE:4525602 bladder 5' read
N45135.1 Clone IMAGE:282957 brain 3' read A
N47704.1 Clone IMAGE:281032 brain 5' read
N47705.1 Clone IMAGE:281032 brain 3' read A
N47958.1 Clone IMAGE:280292 brain 3' read A
N49169.1 Clone IMAGE:280292 brain 5' read P
BG686026.1 Clone IMAGE:4766159 tonsil 5' read
BG750930.1 Clone IMAGE:4873235 eye 5' read
BG897537.1 connective tissue P
N72126.1 Clone IMAGE:291077 skin 3' read
N79468.1 Clone IMAGE:301053 lung 3' read A
BG702830.1 Clone IMAGE:4817313 brain 5' read
DC374322.1 Clone OCBBF2005026 brain 5' read P
DC302330.1 Clone BRACE2001782 brain 5' read P
DC318929.1 Clone BRAWH2001427 brain 5' read P
DC313095.1 Clone BRAMY2002162 brain 5' read P
DC419648.1 Clone UTERU2000429 uterus 5' read P
DC334513.1 Clone BRHIP3023794 brain 5' read P
BI491616.1 Clone IMAGE:2483003 ear 3' read A
BI491617.1 Clone IMAGE:2483003 ear 5' read
BI544984.1 Clone IMAGE:5285028 brain 5' read P
BI915512.1 Clone IMAGE:5241519 brain 5' read P
W24775.1 Clone IMAGE:308159 lung 5' read
BM512421.1 Clone IMAGE:5636316 pancreas 3' read A
BM565023.1 Clone IMAGE:5636316 pancreas 5' read
BM722780.1 Clone UI-E-EO0-ahy-l-03-0-UI eye 5' read
BM756445.1 Clone S2SNU668-24-F03 ascites 5' read
BM760937.1 Clone S2SNU668s1-13-C01 ascites 5' read
BM807861.1 Clone IMAGE:5591317 ovary 5' read P
BM848179.1 Clone S13KMS5-48-G06 stomach 5' read
AL695071.1 Clone DKFZp313L1241 uncharacterized tissue 5' read
AL703161.1 Clone DKFZp686P1518 muscle 5' read P
BQ016215.1 Clone IMAGE:5887333 connective tissue 3' read A
BQ186806.1 Clone UI-E-EJ1-ajy-k-23-0-UI eye 5' read A
BQ269652.1 Clone IMAGE:5782307 pancreas 3' read A
BQ286302.1 Clone IMAGE:5782307 pancreas 5' read
AA029136.1 Clone IMAGE:470030 uterus 5' read
BQ574566.1 Clone UI-H-EZ1-bba-m-02-0-UI bone 3' read A
BQ631377.1 Clone IMAGE:6030399 pancreas 3' read A
BQ631656.1 Clone IMAGE:6030399 pancreas 5' read
BQ631742.1 Clone IMAGE:6030842 pancreas 5' read
BQ632039.1 Clone IMAGE:6030842 pancreas 3' read A
AA037269.1 Clone IMAGE:325901 skin 5' read
BQ776706.1 Clone IMAGE:6031843 pancreas 3' read A
BG120979.1 Clone IMAGE:4445901 liver 5' read P
BQ943953.1 Clone IMAGE:6373754 lung 5' read P
BQ959129.1 Clone IMAGE:6462053 lung 5' read
BU153307.1 Clone IMAGE:6020497 pancreas 5' read
BU169631.1 Clone IMAGE:6020385 pancreas 5' read
GD135670.1 3' read A
BU683371.1 Clone UI-CF-EC1-ace-h-09-0-UI lung 3' read A
AA232888.1 Clone IMAGE:666385 mixed 5' read
AA234332.1 Clone IMAGE:668865 mixed 5' read
AA249473.1 heart 5' read
AA262893.1 Clone IMAGE:668865 mixed 3' read A
CA335716.1 Clone IMAGE:5606742 embryonic tissue 5' read
CA311637.1 Clone UI-CF-FN0-afd-n-17-0-UI lung 3' read A
CA413959.1 Clone UI-H-EZ0-bau-j-07-0-UI bone 3' read A
CA417804.1 Clone UI-H-FE0-bbw-p-22-0-UI bone 3' read A
CA446398.1 Clone UI-H-ED1-axr-c-14-0-UI connective tissue 3' read A
T77325.1 Clone IMAGE:23778 brain 5' read
AA358443.1 lung 5' read
AA382818.1 testis 5' read
AA428412.1 Clone IMAGE:774202 embryonic tissue 3' read A
AA445934.1 Clone IMAGE:774202 embryonic tissue 5' read P
AA463915.1 Clone IMAGE:812697 mixed 3' read A
AA487758.1 Clone IMAGE:840703 lung 5' read
AA648982.1 Clone IMAGE:1186209 lymph node 3' read
AA732434.1 Clone IMAGE:1302931 lymph node 3' read A
AA743357.1 Clone IMAGE:1272102 lymph node 3' read A
AA749414.1 Clone IMAGE:1271171 lymph node 3' read A
AA806835.1 Clone IMAGE:1351104 lymph node 3' read A
AA916802.1 Clone IMAGE:1441502 mammary gland 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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