R = Retrieve links to Related sequences (neighbors).
Use the 
icon (if present) to retrieve links to the Sequence Retrieval System (SRS).
Use the 
icon (if present) to retrieve links to the Ligand Enzyme and Chemical Compound Database .
Use the 
icon (if present) to retrieve links to the Protein Data Bank database.
WARNING: Descriptions of 107 database sequences were not reported due to the
limiting value of parameter V = 50.
>gi|12644307|sp|P52423|PUR3_VIGUN PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE,
CHLOROPLAST PRECURSOR (GART) (GAR TRANSFORMYLASE)
(5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE)
Length = 312
Frame 1 hits (HSPs): ________________________
__________________________________________________
Database sequence: | | | | | | | | 312
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 717 (252.4 bits), Expect = 7.8e-70, P = 7.8e-70
Identities = 136/147 (92%), Positives = 144/147 (97%), Frame = +1
Query: 67 NPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVH 246
+P DLVDTLRKFEVDF+LLAGYLKLIPVELIRA++RSIFNIHPSLLPAFGGKG+YGMKVH
Sbjct: 165 SPCDLVDTLRKFEVDFVLLAGYLKLIPVELIRAFERSIFNIHPSLLPAFGGKGYYGMKVH 224
Query: 247 KAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVV 426
KAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDT EELAARVL EEHQLYVEVV
Sbjct: 225 KAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTAEELAARVLNEEHQLYVEVV 284
Query: 427 EALCEERVVWRQDGVPLIQSKENPNEF 507
EALCEER+VWR+DGVPLIQS+ENPNEF
Sbjct: 285 EALCEERIVWRKDGVPLIQSRENPNEF 311
>gi|7433568|pir||T11574 phosphoribosylglycinamide formyltransferase (EC
2.1.2.2) - cowpea >gi|984818|gb|AAA75367.1| (U30875) glycinamide
ribonucleotide transformylase (GART) [Vigna unguiculata]
Length = 312
Frame 1 hits (HSPs): ________________________
__________________________________________________
Database sequence: | | | | | | | | 312
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 705 (248.2 bits), Expect = 1.5e-68, P = 1.5e-68
Identities = 134/146 (91%), Positives = 142/146 (97%), Frame = +1
Query: 67 NPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVH 246
+P DLVDTLRKFEVDF+LLAGYLKLIPVELIRA++RSIFNIHPSLLPAFGGKG+YGMKVH
Sbjct: 165 SPCDLVDTLRKFEVDFVLLAGYLKLIPVELIRAFERSIFNIHPSLLPAFGGKGYYGMKVH 224
Query: 247 KAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVV 426
KAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDT EELAARVL EEHQLYVEVV
Sbjct: 225 KAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTAEELAARVLNEEHQLYVEVV 284
Query: 427 EALCEERVVWRQDGVPLIQSKENPNE 504
EALCEER+VWR+DGVPLIQS+ENP E
Sbjct: 285 EALCEERIVWRKDGVPLIQSRENPTE 310
>gi|12229915|sp|Q42805|PUR3_SOYBN PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE,
CHLOROPLAST PRECURSOR (GART) (GAR TRANSFORMYLASE)
(5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE)
>gi|7433557|pir||T07781 probable phosphoribosylglycinamide
formyltransferase (EC 2.1.2.2) - soybean
>gi|1321822|emb|CAA65608.1| (X96865) phosphoribosylglycinamide
formyltransferase [Glycine max]
Length = 295
Frame 3 hits (HSPs): __ ____
Frame 1 hits (HSPs): __________________________
__________________________________________________
Database sequence: | | | | | | | 295
0 50 100 150 200 250
Plus Strand HSPs:
Score = 587 (206.6 bits), Expect = 3.8e-59, Sum P(2) = 3.8e-59
Identities = 123/152 (80%), Positives = 129/152 (84%), Frame = +1
Query: 55 RXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPA-FGGKGFY 231
+ ESN SDLVDTLRKFEVDFILLAGYL L K I+ H S+ + F +G +
Sbjct: 145 KDESNGSDLVDTLRKFEVDFILLAGYLNLYQWNDPSLQK--IYIQHSSITSSSFWRQGIH 202
Query: 232 GMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQL 411
GMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPV ANDTVEELAARVLKEEHQL
Sbjct: 203 GMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVQANDTVEELAARVLKEEHQL 262
Query: 412 YVEVVEALCEERVVWRQDGVPLIQSKENPNEFR 510
YVEVVEALCEERVVWRQDGVPLIQSKENPNEFR
Sbjct: 263 YVEVVEALCEERVVWRQDGVPLIQSKENPNEFR 295
Score = 125 (44.0 bits), Expect = 1.4e-06, Sum P(2) = 1.4e-06
Identities = 24/24 (100%), Positives = 24/24 (100%), Frame = +3
Query: 156 DPSLQKIYIQHSSITSSSFWRQGI 227
DPSLQKIYIQHSSITSSSFWRQGI
Sbjct: 178 DPSLQKIYIQHSSITSSSFWRQGI 201
Score = 47 (16.5 bits), Expect = 3.8e-59, Sum P(2) = 3.8e-59
Identities = 9/9 (100%), Positives = 9/9 (100%), Frame = +3
Query: 30 PVILYHISK 56
PVILYHISK
Sbjct: 137 PVILYHISK 145
>gi|4512619|gb|AAD21688.1| (AC004793) This gene is a member of the formyl
transferase family PF|00551 and may be a pseudogene of gb|X74767
phosphoribosylglycinamide formyl transferase (PUR3) from
Arabidopsis thaliana since our sequence differs from PUR3 by an
insertion of an A a> >gi|4753662|emb|CAA52779.2| (X74767)
phosphoribosylglycinamide formyltransferase [Arabidopsis thaliana]
Length = 292
Frame 1 hits (HSPs): __________________________
__________________________________________________
Database sequence: | | | | | | | 292
0 50 100 150 200 250
Plus Strand HSPs:
Score = 591 (208.0 bits), Expect = 1.8e-56, P = 1.8e-56
Identities = 109/147 (74%), Positives = 131/147 (89%), Frame = +1
Query: 67 NPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVH 246
+PS+LVD LRK+ VDF+LLAGYLKLIPVEL++A+ + I NIHP+LLPAFGGKG YG+KVH
Sbjct: 145 SPSELVDVLRKYGVDFVLLAGYLKLIPVELVQAFPKRILNIHPALLPAFGGKGLYGIKVH 204
Query: 247 KAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVV 426
KAV+ SGAR+SGPTIHFV+E YDTGRILAQ V V+ANDT EELA RVL EEH+LYVEVV
Sbjct: 205 KAVLESGARYSGPTIHFVNEEYDTGRILAQSAVRVIANDTPEELAKRVLHEEHKLYVEVV 264
Query: 427 EALCEERVVWRQDGVPLIQSKENPNEF 507
A+CEER+ WR+DGVPLIQ+K+NP+E+
Sbjct: 265 GAICEERIKWREDGVPLIQNKQNPDEY 291
>gi|1709922|sp|P52422|PUR3_ARATH PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE,
CHLOROPLAST PRECURSOR (GART) (GAR TRANSFORMYLASE)
(5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE)
>gi|480622|pir||S37105 phosphoribosylglycinamide formyltransferase
(EC 2.1.2.2) - Arabidopsis thaliana
Length = 226
Frame 1 hits (HSPs): _____________________________
Annotated Domains: _________________________________________________
__________________________________________________
Database sequence: | | | | | | 226
0 50 100 150 200
__________________
Annotated Domains:
BLOCKS BL00373A: Phosphoribosylglycinamide form 38..47
BLOCKS BL00373B: Phosphoribosylglycinamide form 77..86
BLOCKS BL00373C: Phosphoribosylglycinamide form 137..149
BLOCKS BL00373D: Phosphoribosylglycinamide form 170..186
DOMO DM00600: PHOSPHORIBOSYLGLYCINAMIDEFORMYL 30..213
Entrez active site: BY SIMILARITY. 181
PFAM formyl_transf: Formyl transferase 32..218
PRODOM PD106248: PUR3_ARATH 1..30
PRODOM PD001209: FMT(15) PURU(6) PUR2(6) 32..222
PROSITE GART: Phosphoribosylglycinamide formyltr 170..193
__________________
Plus Strand HSPs:
Score = 498 (175.3 bits), Expect = 1.3e-46, P = 1.3e-46
Identities = 94/126 (74%), Positives = 111/126 (88%), Frame = +1
Query: 67 NPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVH 246
+PS+LVD LRK+ VDF+LLAGYLKLIPVEL++A+ + I NIHP+LLPAFGGKG YG+KVH
Sbjct: 99 SPSELVDVLRKYGVDFVLLAGYLKLIPVELVQAFPKRILNIHPALLPAFGGKGLYGIKVH 158
Query: 247 KAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVV 426
KAV+ SGAR+SGPTIHFV+E YDTGRILAQ V V+ANDT EELA RVL E+H+LYVEVV
Sbjct: 159 KAVLESGARYSGPTIHFVNEEYDTGRILAQSAVRVIANDTPEELAKRVLHEDHKLYVEVV 218
Query: 427 EALCEE 444
A+CEE
Sbjct: 219 GAICEE 224
>gi|10639228|emb|CAC11230.1| (AL445063) probable phosphoribosylglycinamide
formyltransferase [Thermoplasma acidophilum]
Length = 203
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | || 203
0 50 100 150 200
Plus Strand HSPs:
Score = 290 (102.1 bits), Expect = 1.4e-24, P = 1.4e-24
Identities = 58/130 (44%), Positives = 81/130 (62%), Frame = +1
Query: 46 IYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKG 225
+ +R + SDL+ + DF LLAG+L ++ +I ++ I N HPSLLP FGGKG
Sbjct: 59 VVRRGRNFQSDLMKEMENSCADFFLLAGFLSILDAGIIERFRNRIINTHPSLLPCFGGKG 118
Query: 226 FYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEH 405
FYGM+VH+AVI SGA+FSG T+HFV E D G I+ QRV+ V DT E L ++ EH
Sbjct: 119 FYGMRVHEAVIESGAKFSGCTVHFVTEEIDGGPIILQRVLQVDDVDTPETLENKIHAIEH 178
Query: 406 QLYVEVVEAL 435
++ + +
Sbjct: 179 SAVLQALNII 188
>gi|5566266|gb|AAD45353.1|AF160196_1 (AF160196) glycinamide ribonucleotide
transformylase [Vigna unguiculata]
Length = 57
Frame 1 hits (HSPs): _________________________________________________
__________________________________________________
Database sequence: | | | | 57
0 20 40
Plus Strand HSPs:
Score = 268 (94.3 bits), Expect = 3.0e-22, P = 3.0e-22
Identities = 51/56 (91%), Positives = 54/56 (96%), Frame = +1
Query: 340 VVPVLANDTVEELAARVLKEEHQLYVEVVEALCEERVVWRQDGVPLIQSKENPNEF 507
VVPVLANDT EELAARVL EEHQLYVEVVEALCEER+VWR+DGVPLIQS+ENPNEF
Sbjct: 1 VVPVLANDTAEELAARVLNEEHQLYVEVVEALCEERIVWRKDGVPLIQSRENPNEF 56
>gi|5419985|emb|CAB46526.1| (AJ243305) 5'-phosphoribosylglycinamide
formyltransferase [Rhizobium leguminosarum]
Length = 186
Frame 1 hits (HSPs): ___________________________________
__________________________________________________
Database sequence: | | | | | 186
0 50 100 150
Plus Strand HSPs:
Score = 255 (89.8 bits), Expect = 7.1e-21, P = 7.1e-21
Identities = 52/130 (40%), Positives = 77/130 (59%), Frame = +1
Query: 49 YQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGF 228
Y +++ + + L + + D + LAGY++L+ I+ Y+ + NIHPSLLP F G
Sbjct: 23 YASKDAHEAAIFSALDELKPDILCLAGYMRLLTATFIQRYQGRMLNIHPSLLPLFPG--- 79
Query: 229 YGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQ 408
+ H+ I +G R +G T+HFV E D G ++ Q VPVL DT E LAARVL EHQ
Sbjct: 80 --LHTHQRAIDAGMRIAGCTVHFVTEGMDEGPVIGQAAVPVLLGDTAESLAARVLTIEHQ 137
Query: 409 LYVEVVEALC 438
+Y + + A+C
Sbjct: 138 IYPQRLAAVC 147
>gi|11257013|pir||G82103 phosphoribosylglycinamide formyltransferase VC2227
[imported] - Vibrio cholerae (group O1 strain N16961)
>gi|9656785|gb|AAF95371.1| (AE004294) phosphoribosylglycinamide
formyltransferase [Vibrio cholerae]
Length = 212
Frame 1 hits (HSPs): ________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 255 (89.8 bits), Expect = 7.1e-21, P = 7.1e-21
Identities = 53/140 (37%), Positives = 83/140 (59%), Frame = +1
Query: 49 YQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGF 228
Y+ ++ + L++ + KF D ++LAGY++++ E +R Y + NIHPSLLP + G
Sbjct: 62 YETRDAFDAALMEQMDKFAPDLVVLAGYMRILSSEFVRHYLGRMINIHPSLLPKYPGLNT 121
Query: 229 YGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQ 408
Y +H +G G ++HFV E D G ++ Q VP+ +DTVEEL ARV +EH+
Sbjct: 122 YQRAIH-----AGDEEHGTSVHFVTEQLDGGPVILQAKVPIFEDDTVEELTARVQDQEHR 176
Query: 409 LYVEVVEALCEERVVWRQDG 468
+Y VV+ EER+ + DG
Sbjct: 177 IYPLVVKWFVEERLAMK-DG 195
>gi|131620|sp|P12040|PUR3_BACSU PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE
(GART) (GAR TRANSFORMYLASE) (5'-PHOSPHORIBOSYLGLYCINAMIDE
TRANSFORMYLASE) >gi|66484|pir||XYBSGF phosphoribosylglycinamide
formyltransferase (EC 2.1.2.2) - Bacillus subtilis
>gi|143372|gb|AAA22682.1| (J02732) phosphoribosyl glycinamide
formyltransferase (PUR-N) [Bacillus subtilis]
>gi|2632965|emb|CAB12471.1| (Z99107) phosphoribosylglycinamide
formyltransferase [Bacillus subtilis]
Length = 195
Frame 1 hits (HSPs): _________________________________
Annotated Domains: ________________________________________________
__________________________________________________
Database sequence: | | | | | 195
0 50 100 150
__________________
Annotated Domains:
BLOCKS BL00373A: Phosphoribosylglycinamide form 8..17
BLOCKS BL00373B: Phosphoribosylglycinamide form 47..56
BLOCKS BL00373C: Phosphoribosylglycinamide form 106..118
BLOCKS BL00373D: Phosphoribosylglycinamide form 134..150
DOMO DM00600: PHOSPHORIBOSYLGLYCINAMIDEFORMYL 2..177
Entrez active site: BY SIMILARITY. 145
PFAM formyl_transf: Formyl transferase 2..182
PRODOM PD001209: FMT(15) PURU(6) PUR2(6) 3..185
PROSITE GART: Phosphoribosylglycinamide formyltr 134..157
__________________
Plus Strand HSPs:
Score = 239 (84.1 bits), Expect = 3.5e-19, P = 3.5e-19
Identities = 51/129 (39%), Positives = 77/129 (59%), Frame = +1
Query: 49 YQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGF 228
Y+ + +++ LR EV+ I LAGY++LI L++AY I NIHPSLLPAF G
Sbjct: 62 YENKAAFEQAIIEQLRLHEVELIALAGYMRLIGDTLLQAYGGKIINIHPSLLPAFPGIDA 121
Query: 229 YGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQ 408
G +G + +G T+H+VDE DTG I+AQ+ + + +DT+E + R+ K EH+
Sbjct: 122 VGQ-----AFRAGVKVAGITVHYVDEGMDTGPIIAQKAIEIDEHDTLETIEQRIHKLEHK 176
Query: 409 LYVEVVEAL 435
Y V++ L
Sbjct: 177 WYPSVIKQL 185
>gi|10173246|dbj|BAB04351.1| (AP001509) phosphoribosylglycinamide
formyltransferase [Bacillus halodurans]
Length = 188
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | 188
0 50 100 150
Plus Strand HSPs:
Score = 238 (83.8 bits), Expect = 4.5e-19, P = 4.5e-19
Identities = 50/129 (38%), Positives = 77/129 (59%), Frame = +1
Query: 49 YQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGF 228
Y E+ ++V L++ ++DF++LAGY++L+ L+ AY+ I NIHPSLLPAF G
Sbjct: 62 YPSKEAYEIEVVQQLKEKQIDFVVLAGYMRLVGPTLLGAYEGRIVNIHPSLLPAFPG--- 118
Query: 229 YGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQ 408
+ + I + + +G TIH+VDE DTG I+AQ V + DT+E L ++ EH+
Sbjct: 119 --LHAIEQAIRANVKVTGVTIHYVDEGMDTGPIIAQEAVSIEEEDTLETLTTKIQAVEHR 176
Query: 409 LYVEVVEAL 435
LY + L
Sbjct: 177 LYPATLHKL 185
>gi|11257018|pir||B81068 phosphoribosylglycinamide formyltransferase NMB1566
[imported] - Neisseria meningitidis (group B strain MD58)
>gi|7226814|gb|AAF41920.1| (AE002507) phosphoribosylglycinamide
formyltransferase [Neisseria meningitidis MC58]
Length = 208
Frame 1 hits (HSPs): __________________________________
__________________________________________________
Database sequence: | | | | | | 208
0 50 100 150 200
Plus Strand HSPs:
Score = 237 (83.4 bits), Expect = 5.7e-19, P = 5.7e-19
Identities = 50/147 (34%), Positives = 87/147 (59%), Frame = +1
Query: 79 LVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVI 258
+++ + ++ D ++LAG+++++ E Y+ + NIHPS+LP+F G + H+ +
Sbjct: 69 MMEKIDAYQPDLVVLAGFMRILTPEFCARYEGRLMNIHPSILPSFTG-----LHTHERAL 123
Query: 259 ASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALC 438
+G R +G TIHFV D G I++Q VVP+L DT +++AARVL EH+LY + V
Sbjct: 124 EAGCRVAGCTIHFVTAELDCGPIVSQGVVPILDGDTADDIAARVLAVEHKLYPKAVADFA 183
Query: 439 EERVVWRQDGVPLIQSKENPNEFR*LS 519
R++ + V ++ EN + R L+
Sbjct: 184 AGRLIIEGNRV---RNSENADAARFLT 207
>gi|7433566|pir||D70374 phosphoribosylglycinamide formyltransferase - Aquifex
aeolicus >gi|2983389|gb|AAC06974.1| (AE000710)
phosphoribosylglycinamide formyltransferase [Aquifex aeolicus]
Length = 216
Frame 1 hits (HSPs): ________________________________
__________________________________________________
Database sequence: | | | | | | 216
0 50 100 150 200
Plus Strand HSPs:
Score = 236 (83.1 bits), Expect = 7.3e-19, P = 7.3e-19
Identities = 50/138 (36%), Positives = 81/138 (58%), Frame = +1
Query: 40 CTIYQRXESNPSD------LVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSL 201
C + QR E PS + L+K V+ ++LAG+++++ ++ + + NIHPSL
Sbjct: 54 CKVIQRKEF-PSKKEFEERMALELKKKGVELVVLAGFMRILSHNFLKYFPNKVINIHPSL 112
Query: 202 LPAFGGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELA 381
+PAF G+ K + G +FSG T+H VDE D G ++ Q VVPVL D LA
Sbjct: 113 IPAF-----QGLHAQKQAVEFGVKFSGCTVHIVDESVDAGPVIVQAVVPVLPEDDENTLA 167
Query: 382 ARVLKEEHQLYVEVVEALCEERVV 453
R+LK EH++ + V+ ++R++
Sbjct: 168 DRILKWEHKILPQTVQWFAQDRII 191
>gi|7473341|pir||F75324 phosphoribosylglycinamide formyltransferase -
Deinococcus radiodurans (strain R1)
>gi|6459814|gb|AAF11574.1|AE002039_4 (AE002039)
phosphoribosylglycinamide formyltransferase [Deinococcus
radiodurans]
Length = 196
Frame 1 hits (HSPs): _____________________________
__________________________________________________
Database sequence: | | | | | 196
0 50 100 150
Plus Strand HSPs:
Score = 236 (83.1 bits), Expect = 7.3e-19, P = 7.3e-19
Identities = 48/109 (44%), Positives = 69/109 (63%), Frame = +1
Query: 109 DFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVIASGARFSGPT 288
D ++L+GY+K + + A+ + NIHPSLLP GG+G YG +VH++V+A+G SG T
Sbjct: 83 DTLVLSGYMKALGPRTLGAFAGRVLNIHPSLLPRHGGRGLYGDRVHESVLAAGDPESGAT 142
Query: 289 IHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEAL 435
+H V D G +L Q VPVL DT++ L ARV EE L + V++L
Sbjct: 143 VHLVTAGIDEGPVLEQVRVPVLPGDTLDTLKARVQAEEAALMLRAVQSL 191
>gi|7433563|pir||S74394 phosphoribosylglycinamide formyltransferase purN -
Synechocystis sp. (strain PCC 6803) >gi|1001169|dbj|BAA10312.1|
(D64001) phosphoribosylglycinamide formyltransferase [Synechocystis
sp.]
Length = 217
Frame 1 hits (HSPs): ____________________________
__________________________________________________
Database sequence: | | | | | | 217
0 50 100 150 200
Plus Strand HSPs:
Score = 235 (82.7 bits), Expect = 9.3e-19, P = 9.3e-19
Identities = 45/122 (36%), Positives = 79/122 (64%), Frame = +1
Query: 49 YQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGF 228
Y E D+V+ R+ V+++++AG+++++ L+ A+ R + NIHPSLLP+F G
Sbjct: 89 YDSREDLDQDIVEHFRQAGVEWVIMAGWMRIVTPVLLDAFSRRVLNIHPSLLPSFRG--- 145
Query: 229 YGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQ 408
++ + +A+G + SG T+H+ + D+G I+AQ VVP+LA+DT E L R+ +EH+
Sbjct: 146 --VRAVEQALAAGVKVSGCTVHYAEATVDSGPIVAQAVVPILADDTGETLHQRIQVQEHR 203
Query: 409 LY 414
L+
Sbjct: 204 LF 205
>gi|11257016|pir||C81800 phosphoribosylglycinamide formyltransferase (EC
2.1.2.2) NMA1755 [imported] - Neisseria meningitidis (group A
strain Z2491) >gi|7380397|emb|CAB84983.1| (AL162757)
phosphoribosylglycinamide transformylase [Neisseria meningitidis
Z2491]
Length = 208
Frame 1 hits (HSPs): __________________________________
__________________________________________________
Database sequence: | | | | | | 208
0 50 100 150 200
Plus Strand HSPs:
Score = 233 (82.0 bits), Expect = 1.5e-18, P = 1.5e-18
Identities = 49/147 (33%), Positives = 87/147 (59%), Frame = +1
Query: 79 LVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVI 258
+++ + ++ D ++LAG+++++ E Y+ + NIHPS+LP+F G + H+ +
Sbjct: 69 MMEKIDAYQPDLVVLAGFMRILTPEFCAHYEGRLMNIHPSVLPSFTG-----LHTHERAL 123
Query: 259 ASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALC 438
+G R +G TIHFV D G I++Q +VP+L DT +++AARVL EH+LY + V
Sbjct: 124 EAGCRVAGCTIHFVTAELDCGPIVSQGIVPILDGDTADDVAARVLAVEHKLYPKAVADFA 183
Query: 439 EERVVWRQDGVPLIQSKENPNEFR*LS 519
R++ + V ++ EN + R L+
Sbjct: 184 AGRLIIEGNRV---RNSENADAARFLT 207
>gi|1172753|sp|P43846|PUR3_HAEIN PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE
(GART) (GAR TRANSFORMYLASE) (5'-PHOSPHORIBOSYLGLYCINAMIDE
TRANSFORMYLASE) >gi|1075153|pir||F64122 phosphoribosylglycinamide
formyltransferase (EC 2.1.2.2) - Haemophilus influenzae (strain Rd
KW20) >gi|1574266|gb|AAC23075.1| (U32822) phosphoribosylglycinamide
formyltransferase (purN) [Haemophilus influenzae Rd]
Length = 212
Frame 1 hits (HSPs): ________________________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
__________________
Annotated Domains:
BLOCKS BL00373A: Phosphoribosylglycinamide form 8..17
BLOCKS BL00373B: Phosphoribosylglycinamide form 47..56
BLOCKS BL00373C: Phosphoribosylglycinamide form 106..118
BLOCKS BL00373D: Phosphoribosylglycinamide form 134..150
DOMO DM00600: PHOSPHORIBOSYLGLYCINAMIDEFORMYL 2..177
Entrez active site: BY SIMILARITY. 145
PFAM formyl_transf: Formyl transferase 2..182
PRODOM PD001209: FMT(15) PURU(6) PUR2(6) 1..182
PRODOM PD106246: PUR3_HAEIN 184..211
PROSITE GART: Phosphoribosylglycinamide formyltr 134..157
__________________
Plus Strand HSPs:
Score = 225 (79.2 bits), Expect = 1.1e-17, P = 1.1e-17
Identities = 48/138 (34%), Positives = 78/138 (56%), Frame = +1
Query: 85 DTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVIAS 264
D L+ VD I+LAGY+K++ + + + I NIHPSLLP + G + ++ I +
Sbjct: 74 DYLQSLAVDLIVLAGYMKILTPKFTQRFAGKILNIHPSLLPKYAG-----LNTYQRAIEA 128
Query: 265 GARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALCEE 444
G G T+HFV+E D G I+ Q VP+ D++EE+ AR ++E+Q+Y V++ E
Sbjct: 129 GDNEHGTTVHFVNEEVDGGAIVLQAKVPIFPEDSIEEVEARTREQEYQIYPLVIKWFTEG 188
Query: 445 RVVWRQDGVPLIQSKENP 498
R+ + D + + K P
Sbjct: 189 RLRLK-DNLAYLDGKALP 205
>gi|7433569|pir||B72277 phosphoribosylglycinamide formyltransferase -
Thermotoga maritima (strain MSB8)
>gi|4981803|gb|AAD36323.1|AE001780_7 (AE001780)
phosphoribosylglycinamide formyltransferase [Thermotoga maritima]
Length = 205
Frame 1 hits (HSPs): ____________________________________
__________________________________________________
Database sequence: | | | | | | 205
0 50 100 150 200
Plus Strand HSPs:
Score = 219 (77.1 bits), Expect = 4.6e-17, P = 4.6e-17
Identities = 51/148 (34%), Positives = 86/148 (58%), Frame = +1
Query: 49 YQRXESNPSD-LVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKG 225
++R E ++ L L + D ++LAG+++++P E++ +K I NIHPSLLPAF G
Sbjct: 62 WERLEKPWAESLKKRLEELNPDLVVLAGFMRILPAEIVERWKWKIVNIHPSLLPAFPGTH 121
Query: 226 FYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEH 405
+ KA G + +G TIHFVDE DTG I+ Q+ V + + ++E L + K EH
Sbjct: 122 ----AIEKAY-EYGVKVTGITIHFVDEGVDTGPIIFQKAVEIKKDWSLERLEEEIHKIEH 176
Query: 406 QLYVEVVEALCEERVVWRQDGVPLIQSKE 492
+ Y V++ + E + W+ +G +I ++
Sbjct: 177 RYYPLVIQKVLEGK--WKIEGRRVILEED 203
>gi|11350790|pir||H83528 phosphoribosylaminoimidazole synthetase PA0944
[imported] - Pseudomonas aeruginosa (strain PAO1)
>gi|9946849|gb|AAG04333.1|AE004528_11 (AE004528)
phosphoribosylaminoimidazole synthetase [Pseudomonas aeruginosa]
Length = 222
Frame 1 hits (HSPs): ________________________________
__________________________________________________
Database sequence: | | | | | | 222
0 50 100 150 200
Plus Strand HSPs:
Score = 218 (76.7 bits), Expect = 5.9e-17, P = 5.9e-17
Identities = 49/143 (34%), Positives = 77/143 (53%), Frame = +1
Query: 49 YQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGF 228
Y ES L + E ++LAG+++++ + +R Y+ + NIHPSLLP KG
Sbjct: 65 YADRESFDEALAQRIDAHEPHLVILAGFMRILSADFVRHYQGRLLNIHPSLLPRH--KGL 122
Query: 229 YGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQ 408
+ H+ + +G R G ++HFV E D G ++ Q V+PV + DT E LA RV +EEH+
Sbjct: 123 H---THQRALEAGDREHGCSVHFVTEELDGGPLVVQAVIPVESQDTPERLARRVHEEEHR 179
Query: 409 LYVEVVEALCEERVVWRQDGVPL 477
+Y + E R+ + G L
Sbjct: 180 IYPLAMRWFAEGRLRLGEQGALL 202
>gi|2144568|pir||I67805 purine synthesis multifunctional protein - mouse
>gi|403493|gb|AAA19013.1| (U01024) glycinamide ribonucleotide
sythetase (GARS), aminoimidazole ribonucleotide synthetase (AIRS),
glycinamide ribonucleotide formyltransferase (GART) [Mus musculus]
Length = 1010
Frame 1 hits (HSPs): _______
Annotated Domains: ______________________________________ __________
__________________________________________________
Database sequence: | | | | | | | | 1010
0 150 300 450 600 750 900
__________________
Annotated Domains:
Entrez domain: phosphoribosylamine--glycine lig 4..424
Entrez domain: phosphoribosylformylglycinamidin 437..766
Entrez domain: phosphoribosylglycinamide formyl 810..1001
Entrez active site: His, Asp #link GART 915
Entrez active site: His, Asp #link GART 951
PROSITE GARS: Phosphoribosylglycinamide syntheta 292..299
PROSITE GART: Phosphoribosylglycinamide formyltr 940..963
__________________
Plus Strand HSPs:
Score = 230 (81.0 bits), Expect = 6.6e-17, P = 6.6e-17
Identities = 48/129 (37%), Positives = 74/129 (57%), Frame = +1
Query: 82 VD-TLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVI 258
VD L +F VD + LAG+++++ +R + + NIHPSLLP+F G H+ V+
Sbjct: 878 VDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSN-----AHEQVL 932
Query: 259 ASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALC 438
+G +G T+HFV E D G+I+ Q VPV DTV L+ RV EH+++ ++ +
Sbjct: 933 EAGVTITGCTVHFVAEDVDAGQIILQEAVPVRRGDTVATLSERVKVAEHKIFPAALQLVA 992
Query: 439 EERVVWRQDG 468
V R+DG
Sbjct: 993 SGAVQLREDG 1002
>gi|6857793 ref|NP_034386.1| phosphoribosylglycinamide formyltransferase [Mus
musculus] >gi|2500003|sp|Q64737|PUR2_MOUSE TRIFUNCTIONAL PURINE
BIOSYNTHETIC PROTEIN ADENOSINE-3 [INCLUDES:
PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (GARS) (GLYCINAMIDE
RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE);
PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (AIRS) (PHOSPHORI>
>gi|691792|gb|AAC53251.1| (U20892) glycinamide ribonucleotide
synthetase-aminoimidazole ribonucleotide synthetase-glycinamide
ribonucleotide formyltransferase [Mus musculus]
Length = 1010
Frame 1 hits (HSPs): _______
__________________________________________________
Database sequence: | | | | | | | | 1010
0 150 300 450 600 750 900
Plus Strand HSPs:
Score = 230 (81.0 bits), Expect = 6.6e-17, P = 6.6e-17
Identities = 48/129 (37%), Positives = 74/129 (57%), Frame = +1
Query: 82 VD-TLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVI 258
VD L +F VD + LAG+++++ +R + + NIHPSLLP+F G H+ V+
Sbjct: 878 VDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSN-----AHEQVL 932
Query: 259 ASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALC 438
+G +G T+HFV E D G+I+ Q VPV DTV L+ RV EH+++ ++ +
Sbjct: 933 EAGVTITGCTVHFVAEDVDAGQIILQEAVPVRRGDTVATLSERVKVAEHKIFPAALQLVA 992
Query: 439 EERVVWRQDG 468
V R+DG
Sbjct: 993 SGAVQLREDG 1002
>gi|12082199|dbj|BAB20826.1| (AB045609) phosphoribosyl glycinamide
transformylase-N [Streptococcus suis]
Length = 183
Frame 1 hits (HSPs): ________________________________
__________________________________________________
Database sequence: | | | | | 183
0 50 100 150
Plus Strand HSPs:
Score = 217 (76.4 bits), Expect = 7.6e-17, P = 7.6e-17
Identities = 49/119 (41%), Positives = 74/119 (62%), Frame = +1
Query: 79 LVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVI 258
++ L + ++D ++LAGY+K++ L+ Y+ I NIHP+ LP F G +G + A
Sbjct: 65 IIQLLDQHQIDLVVLAGYMKIVGPTLLAQYEGRIINIHPAYLPEFPGA--HG--IEDAWN 120
Query: 259 ASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEAL 435
A G SG T+H+VD DTG+I+ Q VP LA+DT+E AR+ + E+QLY V+E L
Sbjct: 121 A-GVAESGVTVHWVDSGVDTGQIIKQVRVPRLADDTLETFEARIHEAEYQLYPAVLEEL 178
>gi|131612|sp|P21872|PUR2_CHICK TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN
ADENOSINE-3 [INCLUDES: PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (GARS)
(GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE
SYNTHETASE); PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (AIRS)
(PHOSPHORI> >gi|68648|pir||AJCHPR purine synthesis multifunctional
protein - chicken >gi|62899|emb|CAA38120.1| (X54200) glycinamide
ribonucleotide synthetase-aminoimidazole ribonucleotide
synthetase-glycinamide ribonucleotide transformylase [Gallus
gallus]
Length = 1003
Frame 1 hits (HSPs): _______
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | | | | 1003
0 150 300 450 600 750 900
__________________
Annotated Domains:
BLOCKS BL00184A: Phosphoribosylglycinamide synt 5..40
BLOCKS BL00184B: Phosphoribosylglycinamide synt 70..122
BLOCKS BL00184C: Phosphoribosylglycinamide synt 146..167
BLOCKS BL00184D: Phosphoribosylglycinamide synt 180..202
BLOCKS BL00184E: Phosphoribosylglycinamide synt 203..240
BLOCKS BL00184F: Phosphoribosylglycinamide synt 284..309
BLOCKS BL00184G: Phosphoribosylglycinamide synt 334..354
BLOCKS BL00184H: Phosphoribosylglycinamide synt 375..387
BLOCKS BL00184I: Phosphoribosylglycinamide synt 410..427
BLOCKS BL00373A: Phosphoribosylglycinamide form 810..819
BLOCKS BL00373B: Phosphoribosylglycinamide form 849..858
BLOCKS BL00373C: Phosphoribosylglycinamide form 908..920
BLOCKS BL00373D: Phosphoribosylglycinamide form 936..952
DOMO DM01620: PHOSPHORIBOSYLAMINE--GLYCINELIG 1..428
DOMO DM01173: PHOSPHORIBOSYLFORMYLGLYCINAMIDI 430..772
DOMO DM00600: PHOSPHORIBOSYLGLYCINAMIDEFORMYL 802..979
Entrez Domain: GARS. 1..433
Entrez Domain: AIRS. 434..805
Entrez Domain: GART. 806..1003
Entrez active site: BY SIMILARITY. 947
Entrez Splicing variant: MISSING (IN GARS-ONLY 434..1003
PFAM GARS: Phosphoribosylglycinamide syntheta 3..426
PFAM AIRS: AIR synthase related protein 450..766
PFAM formyl_transf: Formyl transferase 804..984
PRODOM PD002771: PUR2(17) 4..68
PRODOM PD000180: PUR2(17) CARB(16) PYR1(14) 70..291
PRODOM PD002812: PUR2(17) 293..425
PRODOM PD000644: PUR2(12) THIL(9) HYPE(6) 434..570
PRODOM PD186350: PUR2(9) Q9YHV5(1) PUR5(1) 572..601
PRODOM PD002650: PUR2(10) PUR5(6) 603..629
PRODOM PD002449: PUR2(12) PUR5(6) 647..775
PRODOM PD106241: PUR2_CHICK 777..803
PRODOM PD001209: FMT(15) PURU(6) PUR2(6) 805..995
PROSITE GARS: Phosphoribosylglycinamide syntheta 292..299
PROSITE GART: Phosphoribosylglycinamide formyltr 936..959
__________________
Plus Strand HSPs:
Score = 226 (79.6 bits), Expect = 1.8e-16, P = 1.8e-16
Identities = 48/123 (39%), Positives = 72/123 (58%), Frame = +1
Query: 82 VD-TLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVI 258
VD L +F V+ I LAG+++++ ++ ++ I NIHPSLLP+F G HK V+
Sbjct: 874 VDRVLEEFSVELICLAGFMRILSGPFVKKWEGKILNIHPSLLPSFKGAN-----AHKLVL 928
Query: 259 ASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALC 438
+G R +G T+HFV E D G I+ Q VPV DTVE L+ RV + EH+ + ++ +
Sbjct: 929 EAGVRVTGCTVHFVAEEVDAGAIIFQEAVPVKIGDTVETLSERVKEAEHRAFPAALQLVA 988
Query: 439 EERV 450
V
Sbjct: 989 SGAV 992
>gi|11257010|pir||C82789 5'-phosphoribosylglycinamide transformylase XF0585
[imported] - Xylella fastidiosa (strain 9a5c)
>gi|9105449|gb|AAF83395.1|AE003904_16 (AE003904)
5'-phosphoribosylglycinamide transformylase [Xylella fastidiosa]
Length = 222
Frame 1 hits (HSPs): _________________________
__________________________________________________
Database sequence: | | | | | | 222
0 50 100 150 200
Plus Strand HSPs:
Score = 213 (75.0 bits), Expect = 2.0e-16, P = 2.0e-16
Identities = 45/113 (39%), Positives = 63/113 (55%), Frame = +1
Query: 112 FILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVIASGARFSGPTI 291
+++ AGY++++ I + + I NIHPSLLP G + H +A+G G ++
Sbjct: 87 WVVCAGYMRILSAAFIERFPKRILNIHPSLLPKHRG-----LHTHARALAAGDTEHGASV 141
Query: 292 HFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALCEERV 450
H V D G +LAQ VVP+L NDT E LA RVL EH L V +E L R+
Sbjct: 142 HLVIPELDAGTVLAQAVVPILTNDTAETLAKRVLVREHPLLVATLELLANGRL 194
>gi|387019|gb|AAA60077.1| (M32082) phosphoribosylglycinamide formyltransferase
[Homo sapiens]
Length = 302
Frame 1 hits (HSPs): _____________________
__________________________________________________
Database sequence: | | | | | | || 302
0 50 100 150 200 250 300
Plus Strand HSPs:
Score = 211 (74.3 bits), Expect = 3.3e-16, P = 3.3e-16
Identities = 44/131 (33%), Positives = 73/131 (55%), Frame = +1
Query: 76 DLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAV 255
DLV L +F +D + LAG+++++ ++ + + NIHPSLLP+F G H+
Sbjct: 171 DLV--LEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSN-----AHEQA 223
Query: 256 IASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEAL 435
+ +G +G T+HFV E D G+I+ Q VPV DTV L+ RV EH+++ ++ +
Sbjct: 224 LETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLV 283
Query: 436 CEERVVWRQDG 468
V ++G
Sbjct: 284 ASGTVQLGENG 294
>gi|8050811|gb|AAF71749.1| (AF257743) phosphoribosylglycinamide
formyltransferase; Gart [Danio rerio]
Length = 1017
Frame 1 hits (HSPs): _______
__________________________________________________
Database sequence: | | | | | | | | 1017
0 150 300 450 600 750 900
Plus Strand HSPs:
Score = 221 (77.8 bits), Expect = 6.1e-16, P = 6.1e-16
Identities = 44/126 (34%), Positives = 71/126 (56%), Frame = +1
Query: 91 LRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVIASGA 270
L +F V+ + LAG+++++ +R + + NIHPSLLP+F G + K + +G
Sbjct: 887 LEEFSVELVCLAGFMRILTGPFVRKWSGKMLNIHPSLLPSFKG-----VNAQKQALQAGV 941
Query: 271 RFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALCEERV 450
R +G ++HFV E D G I+ Q VPVL D+ E L+ R+ + EH+ + +E + V
Sbjct: 942 RVTGCSVHFVAEDVDAGAIVVQEAVPVLVTDSEESLSERIREAEHRAFPAALELVSSGAV 1001
Query: 451 VWRQDG 468
R DG
Sbjct: 1002 KLRDDG 1007
>gi|10186068|gb|AAG14610.1|AF293180_2 (AF293180) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
>gi|10186071|gb|AAG14612.1|AF293181_2 (AF293181)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _____________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 207 (72.9 bits), Expect = 8.7e-16, P = 8.7e-16
Identities = 42/158 (26%), Positives = 80/158 (50%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERVVWRQDGVPLIQSKENPNEF 507
+EH +Y V+ + R+ ++ L + P +
Sbjct: 171 TQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQSY 208
>gi|12720221|gb|AAK02104.1| (AE006035) PurN [Pasteurella multocida]
Length = 213
Frame 1 hits (HSPs): ____________________________
__________________________________________________
Database sequence: | | | | | | 213
0 50 100 150 200
Plus Strand HSPs:
Score = 207 (72.9 bits), Expect = 8.7e-16, P = 8.7e-16
Identities = 41/120 (34%), Positives = 69/120 (57%), Frame = +1
Query: 91 LRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVIASGA 270
+ + D I+LAGY+K++ + + I NIHPSLLP + G + ++ + +G
Sbjct: 76 IESVQADLIVLAGYMKILSPAFTQRFAGKILNIHPSLLPKYPG-----LNTYQQALDAGE 130
Query: 271 RFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEALCEERV 450
R G ++HFV+E D G ++ Q VP+ A D +E++ RV +E ++Y VV+ EER+
Sbjct: 131 REHGTSVHFVNEEVDAGAVILQAKVPIFAEDRIEDIEQRVKAQELRIYPLVVKWFVEERL 190
>gi|9972131|gb|AAG10597.1|AF293159_2 (AF293159) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
Length = 213
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 213
0 50 100 150 200
Plus Strand HSPs:
Score = 206 (72.5 bits), Expect = 1.1e-15, P = 1.1e-15
Identities = 41/139 (29%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LVASEFDSREAYDRELIHEIDVYSPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +E+ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDEITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186032|gb|AAG14586.1|AF293168_2 (AF293168) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
>gi|10186035|gb|AAG14588.1|AF293169_2 (AF293169)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186038|gb|AAG14590.1|AF293170_2 (AF293170)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186044|gb|AAG14594.1|AF293172_2 (AF293172)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186047|gb|AAG14596.1|AF293173_2 (AF293173)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186050|gb|AAG14598.1|AF293174_2 (AF293174)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186053|gb|AAG14600.1|AF293175_2 (AF293175)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186056|gb|AAG14602.1|AF293176_2 (AF293176)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186059|gb|AAG14604.1|AF293177_2 (AF293177)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186062|gb|AAG14606.1|AF293178_2 (AF293178)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186074|gb|AAG14614.1|AF293182_2 (AF293182)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186077|gb|AAG14616.1|AF293183_2 (AF293183)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186080|gb|AAG14618.1|AF293184_2 (AF293184)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186083|gb|AAG14620.1|AF293185_2 (AF293185)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186086|gb|AAG14622.1|AF293186_2 (AF293186)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186089|gb|AAG14624.1|AF293187_2 (AF293187)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186092|gb|AAG14626.1|AF293188_2 (AF293188)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186098|gb|AAG14630.1|AF293190_2 (AF293190)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186101|gb|AAG14632.1|AF293191_2 (AF293191)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186104|gb|AAG14634.1|AF293192_2 (AF293192)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186164|gb|AAG14674.1|AF293212_2 (AF293212)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 205 (72.2 bits), Expect = 1.4e-15, P = 1.4e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186041|gb|AAG14592.1|AF293171_2 (AF293171) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 205 (72.2 bits), Expect = 1.4e-15, P = 1.4e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186065|gb|AAG14608.1|AF293179_2 (AF293179) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 205 (72.2 bits), Expect = 1.4e-15, P = 1.4e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186095|gb|AAG14628.1|AF293189_2 (AF293189) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 205 (72.2 bits), Expect = 1.4e-15, P = 1.4e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186008|gb|AAG14570.1|AF293160_2 (AF293160) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
>gi|10186026|gb|AAG14582.1|AF293166_2 (AF293166)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186107|gb|AAG14636.1|AF293193_2 (AF293193)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186110|gb|AAG14638.1|AF293194_2 (AF293194)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186113|gb|AAG14640.1|AF293195_2 (AF293195)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186116|gb|AAG14642.1|AF293196_2 (AF293196)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186119|gb|AAG14644.1|AF293197_2 (AF293197)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186122|gb|AAG14646.1|AF293198_2 (AF293198)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186140|gb|AAG14658.1|AF293204_2 (AF293204)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186143|gb|AAG14660.1|AF293205_2 (AF293205)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186146|gb|AAG14662.1|AF293206_2 (AF293206)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186149|gb|AAG14664.1|AF293207_2 (AF293207)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186152|gb|AAG14666.1|AF293208_2 (AF293208)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186155|gb|AAG14668.1|AF293209_2 (AF293209)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186158|gb|AAG14670.1|AF293210_2 (AF293210)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 204 (71.8 bits), Expect = 1.8e-15, P = 1.8e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDVTARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186011|gb|AAG14572.1|AF293161_2 (AF293161) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
>gi|10186014|gb|AAG14574.1|AF293162_2 (AF293162)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186020|gb|AAG14578.1|AF293164_2 (AF293164)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 204 (71.8 bits), Expect = 1.8e-15, P = 1.8e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LITSAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186125|gb|AAG14648.1|AF293199_2 (AF293199) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
>gi|10186128|gb|AAG14650.1|AF293200_2 (AF293200)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186131|gb|AAG14652.1|AF293201_2 (AF293201)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186134|gb|AAG14654.1|AF293202_2 (AF293202)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
>gi|10186137|gb|AAG14656.1|AF293203_2 (AF293203)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 204 (71.8 bits), Expect = 1.8e-15, P = 1.8e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDVTARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186023|gb|AAG14580.1|AF293165_2 (AF293165) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 203 (71.5 bits), Expect = 2.3e-15, P = 2.3e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LITSAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDVTARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|2500002|sp|Q26255|PUR2_CHITE TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN
ADENOSINE-3 [INCLUDES: PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (GARS)
(GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE
SYNTHETASE); PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (AIRS)
(PHOSPHORI> >gi|254730|gb|AAB23115.1| (S43653) glycinamide
ribonucleotide synthetase, aminoimidazole ribonucleotide
synthetase, glycinamide ribonucleotide transformylase {EC 6.3.4.13,
6.3.3.1, 2.1.2.2} [Chironomus tentans, Peptide, 1371 aa]
Length = 1371
Frame 1 hits (HSPs): ______
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 1371
0 500 1000
__________________
Annotated Domains:
BLOCKS BL00184A: Phosphoribosylglycinamide synt 6..41
BLOCKS BL00184B: Phosphoribosylglycinamide synt 74..126
BLOCKS BL00184C: Phosphoribosylglycinamide synt 149..170
BLOCKS BL00184D: Phosphoribosylglycinamide synt 183..205
BLOCKS BL00184E: Phosphoribosylglycinamide synt 206..243
BLOCKS BL00184F: Phosphoribosylglycinamide synt 287..312
BLOCKS BL00184G: Phosphoribosylglycinamide synt 338..358
BLOCKS BL00184H: Phosphoribosylglycinamide synt 381..393
BLOCKS BL00184I: Phosphoribosylglycinamide synt 416..433
BLOCKS BL00373A: Phosphoribosylglycinamide form 1176..1185
BLOCKS BL00373B: Phosphoribosylglycinamide form 1217..1226
BLOCKS BL00373C: Phosphoribosylglycinamide form 1276..1288
BLOCKS BL00373D: Phosphoribosylglycinamide form 1304..1320
Entrez Domain: GARS. 1..433
Entrez Domain: AIRS. 434..1171
Entrez Domain: GART. 1172..1371
Entrez active site: BY SIMILARITY. 1315
PFAM GARS: Phosphoribosylglycinamide syntheta 4..432
PFAM AIRS: AIR synthase related protein 452..777
PFAM AIRS: AIR synthase related protein 823..1141
PFAM formyl_transf: Formyl transferase 1170..1352
PRODOM PD002771: PUR2(17) 5..64
PRODOM PD000180: PUR2(17) CARB(16) PYR1(14) 66..294
PRODOM PD002812: PUR2(17) 296..430
PRODOM PD000644: PUR2(12) THIL(9) HYPE(6) 438..582
PRODOM PD186350: PUR2(9) Q9YHV5(1) PUR5(1) 584..613
PRODOM PD002650: PUR2(10) PUR5(6) 616..642
PRODOM PD002449: PUR2(12) PUR5(6) 661..758
PRODOM PD096279: PUR2_CHITE 760..804
PRODOM PD000644: PUR2(12) THIL(9) HYPE(6) 806..945
PRODOM PD186350: PUR2(9) Q9YHV5(1) PUR5(1) 947..975
PRODOM PD002650: PUR2(10) PUR5(6) 981..1005
PRODOM PD002449: PUR2(12) PUR5(6) 1022..1140
PRODOM PD106242: PUR2_CHITE 1142..1168
PRODOM PD001209: FMT(15) PURU(6) PUR2(6) 1170..1355
__________________
Plus Strand HSPs:
Score = 217 (76.4 bits), Expect = 2.4e-15, P = 2.4e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Frame = +1
Query: 49 YQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGF 228
Y E+ L + L K V+ I LAG+++++ + +K + NIHPSLLP + G
Sbjct: 1232 YATREAFDVALHNELIKHNVEIICLAGFMRILTPCFVNKWKGKLLNIHPSLLPKYKG--- 1288
Query: 229 YGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEH 405
+ K + SG SG T+HFVDE+ DTG I+ Q +VP+ NDTVE L R+ EH
Sbjct: 1289 --ITAQKDALESGDNESGCTVHFVDENVDTGAIIVQEIVPIFENDTVESLTERIHVAEH 1345
>gi|4028156|gb|AAC96120.1| (AF083221) glycinamide ribonucleotide transformylase
[Takifugu rubripes]
Length = 1008
Frame 1 hits (HSPs): _______
__________________________________________________
Database sequence: | | | | | | | | 1008
0 150 300 450 600 750 900
Plus Strand HSPs:
Score = 215 (75.7 bits), Expect = 2.6e-15, P = 2.6e-15
Identities = 44/132 (33%), Positives = 71/132 (53%), Frame = +1
Query: 73 SDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKA 252
S + L +F V+ + LAG+++++ ++ + + NIHPSLLP+F G + K
Sbjct: 870 STINTVLEEFGVELVCLAGFMRILTGTFVKKWTGKLLNIHPSLLPSFKG-----VNAQKQ 924
Query: 253 VIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEA 432
+ +G R +G T+HFV E D G I+ Q VPVL DT + L R+ + EH+ + +E
Sbjct: 925 ALQAGVRVAGCTVHFVAEEVDAGAIIVQEAVPVLVGDTEDSLCDRIREAEHRAFPTALEL 984
Query: 433 LCEERVVWRQDG 468
+ V DG
Sbjct: 985 VASGTVRLGNDG 996
>gi|1562542|gb|AAB08891.1| (U68765) 5'-phosphoribosylglycinamide transformylase
[Salmonella typhimurium]
Length = 212
Frame 1 hits (HSPs): ________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 202 (71.1 bits), Expect = 2.9e-15, P = 2.9e-15
Identities = 41/141 (29%), Positives = 75/141 (53%), Frame = +1
Query: 76 DLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAV 255
+L+ + + D ++LAG+++++ + Y + NIHPSLLP + G + H+
Sbjct: 70 ELIRKIDAYAPDVVVLAGFMRILSPMFVAHYYGRLLNIHPSLLPKYPG-----LHTHRQA 124
Query: 256 IASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEAL 435
+ +G G ++HFV + D G ++ Q VPV AND+ +++ ARV +EH +Y V+
Sbjct: 125 LENGDEEHGTSVHFVTDELDGGPVILQAKVPVFANDSEDDITARVQTQEHAIYPLVISWF 184
Query: 436 CEERVVWRQDGVPLIQSKENP 498
+ R+ R D + + P
Sbjct: 185 AQGRLKMR-DNAAWLDGRRLP 204
>gi|10186017|gb|AAG14576.1|AF293163_2 (AF293163) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 202 (71.1 bits), Expect = 2.9e-15, P = 2.9e-15
Identities = 40/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDVLDGGPVILQAKVPVFAGDTEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|10186161|gb|AAG14672.1|AF293211_2 (AF293211) phosphoribosylglycinamide
formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 202 (71.1 bits), Expect = 2.9e-15, P = 2.9e-15
Identities = 40/139 (28%), Positives = 73/139 (52%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIARAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A DT +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDTEDDVTARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|131613|sp|P00967|PUR2_DROME TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN
ADENOSINE-3 [INCLUDES: PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (GARS)
(GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE
SYNTHETASE); PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (AIRS)
(PHOSPHORI> >gi|68649|pir||AJFFPM purine synthesis multifunctional
protein - fruit fly (Drosophila melanogaster)
>gi|157482|gb|AAA28563.1| (J02527) Gart polypeptide 4.7 kb
transcript [Drosophila melanogaster] >gi|295747|emb|CAA29612.1|
(X06286) GARS-AIRS-GART polypeptide [Drosophila melanogaster]
Length = 1353
Frame 1 hits (HSPs): _____
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 1353
0 500 1000
__________________
Annotated Domains:
BLOCKS BL00184A: Phosphoribosylglycinamide synt 5..40
BLOCKS BL00184B: Phosphoribosylglycinamide synt 73..125
BLOCKS BL00184C: Phosphoribosylglycinamide synt 149..170
BLOCKS BL00184D: Phosphoribosylglycinamide synt 183..205
BLOCKS BL00184E: Phosphoribosylglycinamide synt 206..243
BLOCKS BL00184F: Phosphoribosylglycinamide synt 287..312
BLOCKS BL00184G: Phosphoribosylglycinamide synt 337..357
BLOCKS BL00184H: Phosphoribosylglycinamide synt 379..391
BLOCKS BL00184I: Phosphoribosylglycinamide synt 416..433
BLOCKS BL00373A: Phosphoribosylglycinamide form 1160..1169
BLOCKS BL00373B: Phosphoribosylglycinamide form 1201..1210
BLOCKS BL00373C: Phosphoribosylglycinamide form 1260..1272
BLOCKS BL00373D: Phosphoribosylglycinamide form 1288..1304
DOMO DM01620: PHOSPHORIBOSYLAMINE--GLYCINELIG 1..434
DOMO DM01173: PHOSPHORIBOSYLFORMYLGLYCINAMIDI 436..781
DOMO DM01173: PHOSPHORIBOSYLFORMYLGLYCINAMIDI 783..1130
DOMO DM00600: PHOSPHORIBOSYLGLYCINAMIDEFORMYL 1152..1331
Entrez Domain: GARS. 1..433
Entrez Domain: AIRS. 434..1152
Entrez Domain: GART. 1153..1353
Entrez active site: BY SIMILARITY. 1299
PFAM GARS: Phosphoribosylglycinamide syntheta 3..432
PFAM AIRS: AIR synthase related protein 457..775
PFAM AIRS: AIR synthase related protein 809..1124
PFAM formyl_transf: Formyl transferase 1154..1336
PRODOM PD002771: PUR2(17) 4..47
PRODOM PD000180: PUR2(17) CARB(16) PYR1(14) 49..294
PRODOM PD002812: PUR2(17) 296..430
PRODOM PD111307: PUR2(2) 432..515
PRODOM PD000644: PUR2(12) THIL(9) HYPE(6) 517..577
PRODOM PD186350: PUR2(9) Q9YHV5(1) PUR5(1) 579..607
PRODOM PD096291: PUR2(2) 609..653
PRODOM PD002449: PUR2(12) PUR5(6) 657..751
PRODOM PD096286: PUR2_DROME 753..782
PRODOM PD034761: PUR2(2) 784..844
PRODOM PD000644: PUR2(12) THIL(9) HYPE(6) 846..919
PRODOM PD186350: PUR2(9) Q9YHV5(1) PUR5(1) 929..956
PRODOM PD002650: PUR2(10) PUR5(6) 961..987
PRODOM PD002449: PUR2(12) PUR5(6) 1003..1124
PRODOM PD036495: PUR2(2) 1126..1152
PRODOM PD001209: FMT(15) PURU(6) PUR2(6) 1154..1339
__________________
Plus Strand HSPs:
Score = 216 (76.0 bits), Expect = 3.1e-15, P = 3.1e-15
Identities = 44/121 (36%), Positives = 69/121 (57%), Frame = +1
Query: 73 SDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKA 252
++L L+ VD I LAG+++++ +R ++ + NIHPSLLP + G + V K
Sbjct: 1224 AELTRNLKAARVDLICLAGFMRVLSAPFVREWRGRLVNIHPSLLPKYPG-----LHVQKQ 1278
Query: 253 VIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEA 432
+ +G + SG T+HFVDE DTG I+ Q VP+L +D + L R+ K EH + +
Sbjct: 1279 ALEAGEKESGCTVHFVDEGVDTGAIIVQAAVPILPDDDEDSLTQRIHKAEHWAFPRALAM 1338
Query: 433 L 435
L
Sbjct: 1339 L 1339
>gi|131621|sp|P08179|PUR3_ECOLI PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE
(GART) (GAR TRANSFORMYLASE) (5'-PHOSPHORIBOSYLGLYCINAMIDE
TRANSFORMYLASE) >gi|66483|pir||XYECGF phosphoribosylglycinamide
formyltransferase (EC 2.1.2.2) - Escherichia coli
>gi|6730114|pdb|1C2T|A Chain A, New Insights Into Inhibitor Design
From The Crystal Structure And Nmr Studies Of E. Coli Gar
Transformylase In Complex With Beta-Gar And
10-Formyl-5,8,10-Trideazafolic Acid. >gi|6730115|pdb|1C2T|B Chain
B, New Insights Into Inhibitor Design From The Crystal Structure
And Nmr Studies Of E. Coli Gar Transformylase In Complex With
Beta-Gar And 10-Formyl-5,8,10-Trideazafolic Acid.
>gi|442731|pdb|1CDE| Phosphoribosylglycinamide Formyltransferase
(E.C.2.1.2.2) (5'-Phosphoribosylglycinamide Transformylase) Complex
With Glycinamide Ribonucleotide And The Inhibitor
5-Deaza-5,6,7,8-Tetrahydrofolate >gi|1065335|pdb|1GAR|A Chain A,
Glycinamide Ribonucleotide Transformylase
(10-Formyltetrahydrofolate-5'-Phosphoribosylglycinamide
Formyltransferase) (E.C.2.1.2.2) Complexed With Burroughs-Wellcome
Inhibitor 1476u89 >gi|1065336|pdb|1GAR|B Chain B, Glycinamide
Ribonucleotide Transformylase
(10-Formyltetrahydrofolate-5'-Phosphoribosylglycinamide
Formyltransferase) (E.C.2.1.2.2) Complexed With Burroughs-Wellcome
Inhibitor 1476u89 >gi|442965|pdb|1GRC|A Chain A, Glycinamide
Ribonucleotide Transformylase (E.C.2.1.2.2) >gi|442966|pdb|1GRC|B
Chain B, Glycinamide Ribonucleotide Transformylase (E.C.2.1.2.2)
>gi|147426|gb|AAA83899.1| (M13747) purN gene product [Escherichia
coli] >gi|1788846|gb|AAC75553.1| (AE000336)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli
K12] >gi|1805560|dbj|BAA16388.1| (D90878) phosphoribosylglycinamide
formyltransferase (EC 2.1.2.2) [Escherichia coli]
>gi|10186029|gb|AAG14584.1|AF293167_2 (AF293167)
phosphoribosylglycinamide formyltransferase 1 [Escherichia coli]
Length = 212
Frame 1 hits (HSPs): _________________________________
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
__________________
Annotated Domains:
BLOCKS BL00373A: Phosphoribosylglycinamide form 7..16
BLOCKS BL00373B: Phosphoribosylglycinamide form 88..97
BLOCKS BL00373C: Phosphoribosylglycinamide form 105..117
BLOCKS BL00373D: Phosphoribosylglycinamide form 133..149
DOMO DM00600: PHOSPHORIBOSYLGLYCINAMIDEFORMYL 1..176
Entrez active site 144
Entrez mutagenized site: D->N: INACTIVATES ENZY 144
PFAM formyl_transf: Formyl transferase 1..181
PRODOM PD001209: FMT(15) PURU(6) PUR2(6) 3..180
PRODOM PD036496: P74882(1) PUR3(1) 182..211
PROSITE GART: Phosphoribosylglycinamide formyltr 133..156
PROSITE LEUCINE_ZIPPER: Leucine zipper pattern. 104..125
__________________
Plus Strand HSPs:
Score = 201 (70.8 bits), Expect = 3.7e-15, P = 3.7e-15
Identities = 39/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A D+ +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|809280|pdb|1CDD|A Chain A, Phosphoribosylglycinamide Formyltransferase
(E.C.2.1.2.2) (5'-Phosphoribosylglycinamide Transformylase)
>gi|809281|pdb|1CDD|B Chain B, Phosphoribosylglycinamide
Formyltransferase (E.C.2.1.2.2) (5'-Phosphoribosylglycinamide
Transformylase)
Length = 212
Frame 1 hits (HSPs): _________________________________
__________________________________________________
Database sequence: | | | | | | 212
0 50 100 150 200
Plus Strand HSPs:
Score = 201 (70.8 bits), Expect = 3.7e-15, P = 3.7e-15
Identities = 39/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A D+ +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|6730124|pdb|1C3E|A Chain A, New Insights Into Inhibitor Design From The
Crystal Structure And Nmr Studies Of E. Coli Gar Transformylate In
Complex With Beta-Gar And 10-Formyl-5,8,10-Trideazafolic Acid.
>gi|6730125|pdb|1C3E|B Chain B, New Insights Into Inhibitor Design
From The Crystal Structure And Nmr Studies Of E. Coli Gar
Transformylate In Complex With Beta-Gar And
10-Formyl-5,8,10-Trideazafolic Acid
Length = 209
Frame 1 hits (HSPs): ________________________________
__________________________________________________
Database sequence: | | | | | | 209
0 50 100 150 200
Plus Strand HSPs:
Score = 201 (70.8 bits), Expect = 3.7e-15, P = 3.7e-15
Identities = 39/139 (28%), Positives = 74/139 (53%), Frame = +1
Query: 34 LYCTIYQRXESNPSDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAF 213
L + + E+ +L+ + + D ++LAG+++++ + Y + NIHPSLLP +
Sbjct: 56 LIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKY 115
Query: 214 GGKGFYGMKVHKAVIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVL 393
G + H+ + +G G ++HFV + D G ++ Q VPV A D+ +++ ARV
Sbjct: 116 PG-----LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQ 170
Query: 394 KEEHQLYVEVVEALCEERV 450
+EH +Y V+ + R+
Sbjct: 171 TQEHAIYPLVISWFADGRL 189
>gi|7297208|gb|AAF52474.1| (AE003615) ade3 gene product [Drosophila
melanogaster]
Length = 1747
Frame 1 hits (HSPs): ____
__________________________________________________
Database sequence: | | | | | 1747
0 500 1000 1500
Plus Strand HSPs:
Score = 216 (76.0 bits), Expect = 4.2e-15, P = 4.2e-15
Identities = 44/121 (36%), Positives = 69/121 (57%), Frame = +1
Query: 73 SDLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKA 252
++L L+ VD I LAG+++++ +R ++ + NIHPSLLP + G + V K
Sbjct: 1618 AELTRNLKAARVDLICLAGFMRVLSAPFVREWRGRLVNIHPSLLPKYPG-----LHVQKQ 1672
Query: 253 VIASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEA 432
+ +G + SG T+HFVDE DTG I+ Q VP+L +D + L R+ K EH + +
Sbjct: 1673 ALEAGEKESGCTVHFVDEGVDTGAIIVQAAVPILPDDDEDSLTQRIHKAEHWAFPRALAM 1732
Query: 433 L 435
L
Sbjct: 1733 L 1733
>gi|4503915 ref|NP_000810.1| phosphoribosylglycinamide formyltransferase,
phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole
synthetase; phosphoribosylglycinamide formyltransferase [Homo
sapiens] >gi|11526207 ref|XP_009737.1| phosphoribosylglycinamide
formyltransferase, phosphoribosylglycinamide synthetase,
phosphoribosylaminoimidazole synthetase [Homo sapiens]
>gi|131616|sp|P22102|PUR2_HUMAN TRIFUNCTIONAL PURINE BIOSYNTHETIC
PROTEIN ADENOSINE-3 [INCLUDES: PHOSPHORIBOSYLAMINE--GLYCINE LIGASE
(GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE)
(PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE);
PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (AIRS) (PHOSPHORI>
>gi|68647|pir||AJHUPR purine synthesis multifunctional protein -
human >gi|31642|emb|CAA38119.1| (X54199) glycinamide ribonucleotide
synthetase-aminoimidazole ribonucleotide synthetase-glycinamide
ribonucleotide transformylase [Homo sapiens]
Length = 1010
Frame 1 hits (HSPs): _______
__________________________________________________
Database sequence: | | | | | | | | 1010
0 150 300 450 600 750 900
Plus Strand HSPs:
Score = 211 (74.3 bits), Expect = 7.1e-15, P = 7.1e-15
Identities = 44/131 (33%), Positives = 73/131 (55%), Frame = +1
Query: 76 DLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAV 255
DLV L +F +D + LAG+++++ ++ + + NIHPSLLP+F G H+
Sbjct: 879 DLV--LEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSN-----AHEQA 931
Query: 256 IASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEAL 435
+ +G +G T+HFV E D G+I+ Q VPV DTV L+ RV EH+++ ++ +
Sbjct: 932 LETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQLV 991
Query: 436 CEERVVWRQDG 468
V ++G
Sbjct: 992 ASGTVQLGENG 1002
>gi|12724522|gb|AAK05621.1|AE006383_5 (AE006383) phosphoribosylglycinamide
formyltransferase (EC 2.1.2.2) [Lactococcus lactis subsp. lactis]
Length = 182
Frame 1 hits (HSPs): ________________________________
__________________________________________________
Database sequence: | | | | | 182
0 50 100 150
Plus Strand HSPs:
Score = 198 (69.7 bits), Expect = 7.8e-15, P = 7.8e-15
Identities = 47/119 (39%), Positives = 69/119 (57%), Frame = +1
Query: 79 LVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAVI 258
LV+ L+ E+D ILLAGY+K+I ++ YK I N+HPS LP F G + H+A
Sbjct: 66 LVEILKDQEIDLILLAGYMKIIGATVLSKYKGKIINVHPSYLPDFAGSPHAIEESHEA-- 123
Query: 259 ASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEAL 435
G G +IH+VDE DTG ++AQ + + ++ +E V + EH+LY EVV +
Sbjct: 124 KKGL---GISIHYVDEGVDTGELIAQ--ISLAYHEDLEVYERSVHEAEHKLYPEVVRQI 177
>gi|131614|sp|P16340|PUR2_DROPS TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN
ADENOSINE-3 [INCLUDES: PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (GARS)
(GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE
SYNTHETASE); PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (AIRS)
(PHOSPHORI> >gi|68650|pir||AJFFPP purine synthesis multifunctional
protein - fruit fly (Drosophila pseudoobscura)
>gi|295787|emb|CAA29611.1| (X06285) GARS-AIRS-GART polypeptide
[Drosophila pseudoobscura]
Length = 1364
Frame 1 hits (HSPs): ______
Annotated Domains: __________________________________________________
__________________________________________________
Database sequence: | | | | 1364
0 500 1000
__________________
Annotated Domains:
BLOCKS BL00184A: Phosphoribosylglycinamide synt 5..40
BLOCKS BL00184B: Phosphoribosylglycinamide synt 73..125
BLOCKS BL00184C: Phosphoribosylglycinamide synt 149..170
BLOCKS BL00184D: Phosphoribosylglycinamide synt 183..205
BLOCKS BL00184E: Phosphoribosylglycinamide synt 206..243
BLOCKS BL00184F: Phosphoribosylglycinamide synt 287..312
BLOCKS BL00184G: Phosphoribosylglycinamide synt 337..357
BLOCKS BL00184H: Phosphoribosylglycinamide synt 379..391
BLOCKS BL00184I: Phosphoribosylglycinamide synt 416..433
BLOCKS BL00373A: Phosphoribosylglycinamide form 1162..1171
BLOCKS BL00373B: Phosphoribosylglycinamide form 1203..1212
BLOCKS BL00373C: Phosphoribosylglycinamide form 1262..1274
BLOCKS BL00373D: Phosphoribosylglycinamide form 1290..1306
Entrez Domain: GARS. 1..434
Entrez Domain: AIRS. 435..1154
Entrez Domain: GART. 1155..1364
Entrez active site: BY SIMILARITY. 1301
PFAM GARS: Phosphoribosylglycinamide syntheta 3..432
PFAM AIRS: AIR synthase related protein 457..775
PFAM AIRS: AIR synthase related protein 811..1126
PFAM formyl_transf: Formyl transferase 1156..1338
PRODOM PD002771: PUR2(17) 5..47
PRODOM PD000180: PUR2(17) CARB(16) PYR1(14) 49..294
PRODOM PD002812: PUR2(17) 296..430
PRODOM PD111307: PUR2(2) 432..515
PRODOM PD000644: PUR2(12) THIL(9) HYPE(6) 517..577
PRODOM PD186350: PUR2(9) Q9YHV5(1) PUR5(1) 579..607
PRODOM PD096291: PUR2(2) 609..653
PRODOM PD002449: PUR2(12) PUR5(6) 657..784
PRODOM PD034761: PUR2(2) 786..846
PRODOM PD000644: PUR2(12) THIL(9) HYPE(6) 848..921
PRODOM PD186350: PUR2(9) Q9YHV5(1) PUR5(1) 931..960
PRODOM PD002650: PUR2(10) PUR5(6) 962..989
PRODOM PD002449: PUR2(12) PUR5(6) 1006..1126
PRODOM PD036495: PUR2(2) 1128..1154
PRODOM PD001209: FMT(15) PURU(6) PUR2(6) 1156..1341
__________________
Plus Strand HSPs:
Score = 212 (74.6 bits), Expect = 8.3e-15, P = 8.3e-15
Identities = 45/120 (37%), Positives = 67/120 (55%), Frame = +1
Query: 76 DLVDTLRKFEVDFILLAGYLKLIPVELIRAYKRSIFNIHPSLLPAFGGKGFYGMKVHKAV 255
+L L+ V+FI LAG+++++ V +R ++ + NIHPSLLP F G + V K
Sbjct: 1227 ELTRHLKTARVEFICLAGFMRILSVPFVREWRGRLINIHPSLLPKFPG-----LHVQKQA 1281
Query: 256 IASGARFSGPTIHFVDEHYDTGRILAQRVVPVLANDTVEELAARVLKEEHQLYVEVVEAL 435
+ +G SG T+H+VDE DTG I+ Q VP+L D E L R+ EH + + L
Sbjct: 1282 LEAGETESGCTVHYVDEGVDTGAIIVQAAVPILPGDDEETLTQRIHYAEHWAFPRALALL 1341
WARNING: HSPs involving 107 database sequences were not reported due to the
limiting value of parameter B = 50.
Parameters:
filter=none
matrix=BLOSUM62
V=50
B=50
E=10
gi
H=1
sort_by_pvalue
echofilter
ctxfactor=5.97
Query ----- As Used ----- ----- Computed ----
Frame MatID Matrix name Lambda K H Lambda K H
Std. 0 BLOSUM62 0.318 0.135 0.401
+3 0 BLOSUM62 0.318 0.135 0.401 0.354 0.157 0.620
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+2 0 BLOSUM62 0.318 0.135 0.401 0.356 0.159 0.590
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
+1 0 BLOSUM62 0.318 0.135 0.401 0.332 0.146 0.468
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-1 0 BLOSUM62 0.318 0.135 0.401 0.350 0.157 0.566
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-2 0 BLOSUM62 0.318 0.135 0.401 0.357 0.160 0.607
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
-3 0 BLOSUM62 0.318 0.135 0.401 0.340 0.144 0.490
Q=9,R=2 0.244 0.0300 0.180 n/a n/a n/a
Query
Frame MatID Length Eff.Length E S W T X E2 S2
+3 0 210 207 10. 77 3 12 22 0.098 35
31 0.11 38
+2 0 211 209 10. 77 3 12 22 0.099 35
31 0.11 38
+1 0 211 208 10. 77 3 12 22 0.098 35
31 0.11 38
-1 0 211 208 10. 77 3 12 22 0.098 35
31 0.11 38
-2 0 211 209 10. 77 3 12 22 0.099 35
31 0.11 38
-3 0 210 207 10. 77 3 12 22 0.098 35
31 0.11 38
Statistics:
Database: /usr/local/dot5/sl_home/beauty/seqdb/blast/nr
Title: nr
Release date: unknown
Posted date: 4:06 PM CST Feb 28, 2001
Format: BLAST
# of letters in database: 197,782,623
# of sequences in database: 625,274
# of database sequences satisfying E: 157
No. of states in DFA: 598 (59 KB)
Total size of DFA: 257 KB (320 KB)
Time to generate neighborhood: 0.01u 0.01s 0.02t Elapsed: 00:00:00
No. of threads or processors used: 6
Search cpu time: 220.98u 1.15s 222.13t Elapsed: 00:00:37
Total cpu time: 221.06u 1.19s 222.25t Elapsed: 00:00:37
Start: Wed Jan 23 16:40:50 2002 End: Wed Jan 23 16:41:27 2002
WARNINGS ISSUED: 2
Annotated Domains Database: March 14, 2000
Release Date: March 14, 2000