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UGID:135078     UniGene Hs.25674     Homo sapiens (human)   MBD2
Methyl-CpG binding domain protein 2 (MBD2)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_003918.1 methyl-CpG binding domain protein 2 isoform 1 H. sapiens 100.0 410
XP_001499825.2 PREDICTED: similar to methyl-CpG binding domain protein 2 E. caballus 100.0 268
XP_512139.2 PREDICTED: similar to methyl-CpG binding protein MBD2 P. troglodytes 99.8 458
XP_001082249.1 PREDICTED: similar to methyl-CpG binding domain protein 2 isoform 1 M. mulatta 99.8 411
NP_034903.2 methyl-CpG binding domain protein 2 M. musculus 98.8 413
NP_001083787.1 methyl-CpG binding protein MBD2 X. laevis 90.9 263
NP_997933.1 methyl-CpG binding domain protein 2 D. rerio 84.6 253

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: connective tissue; uncharacterized tissue; uterus; prostate; lung; placenta; brain; lymph node; eye; liver; esophagus; embryonic tissue; mouth; bladder; vascular; adrenal gland; larynx; bone marrow; ear; pituitary gland; muscle; blood; skin; mixed; pancreas; intestine; ovary; mammary gland; heart; pharynx; testis; stomach; parathyroid; nerve; ganglia; bone; kidney; adipose tissue; thyroid; ascites
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q21
UniSTS entry: Chr 18 SHGC-81536
UniSTS entry: Chr 18 RH98619
UniSTS entry: Chr 18 RH36568
UniSTS entry: Chr Y D10S16
UniSTS entry: Chr Y D11S2921
UniSTS entry: Chr Y GDB:434012
UniSTS entry: Chr Y (n/a)
UniSTS entry: Chr Y (n/a)
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AF039701.1 Homo sapiens antigen NY-CO-41 (NY-CO-41) mRNA, partial cds P
AF072242.1 Homo sapiens methyl-CpG binding protein MBD2 (MBD2) mRNA, complete cds PA
AF072246.1 Homo sapiens testis specific methyl-CpG binding protein MBD2 (MBD2) mRNA, partial cds P
NM_003927.3 Homo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant 1, mRNA P
CR615715.1 full-length cDNA clone CS0DG004YH03 of B cells (Ramos cell line) of Homo sapiens (human) P
CR615628.1 full-length cDNA clone CS0DJ003YE13 of T cells (Jurkat cell line) Cot 10-normalized of Homo sapiens (human) P
CR608921.1 full-length cDNA clone CS0DI058YO22 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR603954.1 full-length cDNA clone CS0DE014YD02 of Placenta of Homo sapiens (human) P
CR592999.1 full-length cDNA clone CS0DI063YN24 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR592850.1 full-length cDNA clone CS0DM013YH10 of Fetal liver of Homo sapiens (human) P
NM_015832.3 Homo sapiens methyl-CpG binding domain protein 2 (MBD2), transcript variant testis-specific, mRNA P
BC032638.1 Homo sapiens methyl-CpG binding domain protein 2, mRNA (cDNA clone MGC:45085 IMAGE:5496721), complete cds PA
AL110266.1 Homo sapiens mRNA; cDNA DKFZp586O0821 (from clone DKFZp586O0821) PA
AF072252.1 Homo sapiens methyl-CpG binding protein MBD2 (MBD2) gene, 3' UTR

EST sequences (286)

AI014977.1 Clone IMAGE:1640768 testis 3' read A
AI049757.1 Clone IMAGE:1699828 kidney 3' read A
AI055997.1 Clone IMAGE:1648532 parathyroid 3' read A
AI074121.1 Clone IMAGE:1679142 skin 3' read A
AI138289.1 Clone IMAGE:1735884 testis 3' read A
AI151139.1 Clone IMAGE:1721208 uterus 3' read A
BX091908.1 Clone IMAGp998I151748_;_IMAGE:713558 ovary P
AI209107.1 Clone IMAGE:1838565 testis 3' read A
AI261965.1 Clone IMAGE:1871724 intestine 3' read A
CB134142.1 Clone L14ChoiCK0-16-B02 liver 5' read
CB147990.1 Clone L9SNU354-15-D04 liver 5' read P
AI300031.1 Clone IMAGE:1909991 lung 3' read A
AI345969.1 Clone IMAGE:1926197 intestine 3' read A
AI358361.1 Clone IMAGE:1991604 uterus 3' read P
AI360013.1 Clone IMAGE:2019141 brain 3' read A
AI422922.1 Clone IMAGE:2096473 brain 3' read A
R50060.1 Clone IMAGE:153042 mammary gland 5' read
R50061.1 Clone IMAGE:153042 mammary gland 3' read
AI354987.1 Clone IMAGE:1961395 esophagus 3' read A
AI493599.1 Clone IMAGE:2120656 pancreas 3' read A
AI538314.1 Clone IMAGE:2191772 uterus 3' read A
AI573027.1 Clone IMAGE:2174423 lymph node 3' read A
AI679787.1 Clone IMAGE:2257012 stomach 3' read A
AI798866.1 Clone IMAGE:2348673 mixed 3' read A
AL047967.1 Clone DKFZp586C1023 uterus A
AI827820.1 Clone IMAGE:2357409 mixed 3' read PA
AI888774.1 Clone IMAGE:2447540 stomach 3' read PA
AI936203.1 Clone IMAGE:2459987 prostate 3' read A
BX324882.2 Clone CS0DI071YH22 placenta 3' read P
BX348759.2 Clone CS0DI003YK18 placenta 5' read
BX358064.2 Clone CS0DI033YD07 placenta 3' read P
BX395638.2 Clone CS0DI003YK18 placenta 5' read
BX331233.2 Clone CS0DB001YM02 uncharacterized tissue 3' read
BX331314.2 Clone CS0DB003YM17 uncharacterized tissue 3' read P
BX352937.2 Clone CS0DB006YP13 uncharacterized tissue 3' read
BX414050.2 Clone CS0DG006YG01 uncharacterized tissue 3' read P
AI961175.1 Clone IMAGE:2475539 uncharacterized tissue 3' read A
BX449102.2 Clone CS0DM013YH10 liver 3' read P
BX449103.2 Clone CS0DM013YH10 liver 5' read P
AW001188.1 Clone IMAGE:2521087 intestine 3' read A
AW028930.1 Clone IMAGE:2542123 stomach 3' read A
CD679334.1 Clone hq08g12 eye 5' read
CD703264.1 pharynx P
AW062622.1 intestine P
AW070689.1 Clone IMAGE:2568219 mammary gland 3' read A
AW084541.1 Clone IMAGE:2559176 intestine 3' read P
AW235259.1 Clone IMAGE:2688095 uncharacterized tissue 3' read A
CF596721.1 Clone IMAGE:30704395 ovary 5' read P
AW244071.1 Clone IMAGE:2570250 connective tissue 3' read A
AW244080.1 Clone IMAGE:2570251 connective tissue 3' read A
AW274866.1 Clone IMAGE:2688727 uncharacterized tissue 3' read A
AW406193.1 Clone IMAGE:3059157 lymph node 5' read P
AW503335.1 Clone IMAGE:3078638 lymph node 5' read P
AW512590.1 Clone IMAGE:2849629 lymph node 3' read A
AW514002.1 Clone IMAGE:2792552 uterus 3' read A
AW571412.1 Clone IMAGE:2850636 lymph node 3' read A
AW575858.1 Clone IMAGE:3058899 lymph node 3' read A
AW797472.1 uterus P
CK825135.1 Clone IMAGE:5594185 pancreas 3' read P
CN263723.1 embryonic tissue 5' read P
CN272401.1 embryonic tissue 5' read
CN276962.1 embryonic tissue 5' read
AW959255.1 uncharacterized tissue P
AW959261.1 uncharacterized tissue P
CN364257.1 embryonic tissue 5' read P
BE153247.1 mouth P
H22139.1 Clone IMAGE:160492 mammary gland 3' read
H22175.1 Clone IMAGE:160492 mammary gland 5' read
CR739354.1 Clone IMAGp998F144380_;_IMAGE:1724173 uncharacterized tissue 5' read
BE379939.1 Clone IMAGE:3511015 bladder 5' read P
BE385660.1 Clone IMAGE:3618742 skin 5' read P
BE540652.1 Clone IMAGE:3447889 placenta 5' read
BP386888.1 Clone hbt06283 pancreas 3' read
R84872.1 Clone IMAGE:275017 mixed 5' read P
R85806.1 Clone IMAGE:275017 mixed 3' read
R86903.1 Clone IMAGE:197293 mixed 5' read P
R86915.1 Clone IMAGE:197317 mixed 5' read P
BE878002.1 Clone IMAGE:3892098 lung 5' read
BE878549.1 Clone IMAGE:3894788 lung 5' read P
D61748.1 Clone GEN-205G02 vascular 5' read
BE858673.1 Clone IMAGE:3305264 brain 3' read PA
BP421292.1 Clone HIE04644r intestine 3' read P
BF029239.1 Clone IMAGE:3997407 bladder 5' read P
AV734938.1 Clone cdABFD01 adrenal gland 5' read P
CR975210.1 Clone RZPDp9016G0739 uncharacterized tissue 5' read P
CR974826.1 Clone RZPDp9016I1030 uncharacterized tissue 5' read P
CR976437.1 Clone RZPDp9017M0616 uncharacterized tissue 5' read P
BF085039.1 placenta
BF089023.1 larynx P
AV752142.1 Clone NPDAYG12 pituitary gland 5' read P
CR988667.1 Clone RZPDp9016E0322 uncharacterized tissue 5' read P
CR993171.1 Clone RZPDp9017J0418 uncharacterized tissue 5' read P
CR994466.1 Clone RZPDp9017F1640 uncharacterized tissue 5' read P
CR994700.1 Clone RZPDp9016P0129 uncharacterized tissue 5' read P
CT004369.1 Clone RZPDp9017P1637 uncharacterized tissue 5' read P
BF215880.1 Clone IMAGE:4093731 brain 5' read
H54447.1 Clone IMAGE:203167 mixed 3' read
H54537.1 Clone IMAGE:203167 mixed 5' read P
BF243440.1 Clone IMAGE:4106723 bone marrow 5' read P
BF355808.1 larynx
DV460114.1 Clone n5683 ear 5' read
BF671291.1 Clone IMAGE:4292340 muscle 5' read P
BF672246.1 Clone IMAGE:4291761 muscle 5' read P
DA496577.1 Clone FCBBF3009465 brain 5' read
BF856562.1 prostate P
BF856474.1 prostate
BF856482.1 prostate P
BF856485.1 prostate P
BF856489.1 prostate
AW605864.1 mouth P
DA523665.1 Clone FEBRA2014542 brain 5' read
AW613131.1 Clone IMAGE:2957733 intestine 3' read A
H71458.1 Clone IMAGE:239218 pharynx 3' read
H71587.1 Clone IMAGE:239218 pharynx 5' read P
AV723795.1 Clone HTBAQC07 brain 5' read PA
DA528001.1 Clone FEBRA2020314 brain 5' read
BF439831.1 Clone IMAGE:3405656 brain 3' read A
BF478208.1 Clone IMAGE:3698411 uncharacterized tissue 3' read
BF593814.1 Clone IMAGE:3276204 brain 3' read
DB314757.1 Clone D9OST2004193 blood 3' read A
DB372082.1 Clone OVARC1001901 ovary 3' read A
DW410063.1 liver
DW432907.1 liver P
DW438773.1 liver
BF831300.1 larynx
BF834183.1 mouth
BF837995.1 larynx P
BF839444.1 larynx P
BF988422.1 placenta P
BF988423.1 placenta
BF902686.1 blood P
BF912795.1 uterus P
BF912801.1 uterus P
BF912804.1 uterus P
AL542662.3 Clone CS0DE014YD02 placenta 5' read P
AL550523.3 Clone CS0DI058YO22 placenta 5' read P
AL557345.3 Clone CS0DH004YD21 blood 5' read P
AL557914.3 Clone CS0DJ003YE13 blood 5' read P
AL560011.3 Clone CS0DG004YH03 uncharacterized tissue 3' read P
AL560012.3 Clone CS0DG004YH03 uncharacterized tissue 5' read P
AL569537.3 Clone CS0DE014YD02 placenta 3' read P
AL574468.3 Clone CS0DI058YO22 placenta 3' read P
AL575111.3 Clone CS0DI063YN24 placenta 3' read P
AL579399.3 Clone CS0DH004YD21 blood 3' read P
AL579855.3 Clone CS0DJ003YE13 blood 3' read P
BG222403.1 Clone IMAGE:4348354 mouth A
BG291944.1 Clone IMAGE:4517593 bladder 5' read P
EC440019.1 prostate
EC452164.1 prostate
EC459964.1 prostate
EC477944.1 prostate
BG435792.1 Clone IMAGE:4605864 placenta 5' read
EC576371.1 prostate
EC577831.1 prostate
EC578237.1 prostate
BG402778.1 Clone IMAGE:4525691 bladder 5' read PA
BF170140.1 blood P
BF171370.1 blood
D79691.1 Clone GEN-307D10 vascular 5' read
BG538171.1 Clone IMAGE:4691548 lung 5' read P
BG572518.1 Clone IMAGE:4720893 placenta 5' read P
BG181926.1 connective tissue
BG182442.1 connective tissue
BG183476.1 connective tissue A
BG186210.1 connective tissue A
BG186643.1 connective tissue A
BG187134.1 connective tissue A
BG187529.1 connective tissue A
BG188185.1 connective tissue A
BG188729.1 connective tissue
BG189234.1 connective tissue A
BG190352.1 connective tissue A
N52360.1 Clone IMAGE:284508 brain 3' read A
BG195442.1 connective tissue P
BG195443.1 connective tissue A
BG195908.1 connective tissue A
BG198995.1 connective tissue A
BG202076.1 connective tissue A
BG207308.1 connective tissue
BG208351.1 connective tissue P
BG208352.1 connective tissue A
BG213084.1 connective tissue A
BG215215.1 connective tissue A
BG215790.1 connective tissue A
BG217885.1 connective tissue A
BG218502.1 connective tissue
BG677183.1 Clone IMAGE:4749110 skin 5' read P
BG678883.1 Clone IMAGE:4749837 skin 5' read P
N64314.1 Clone IMAGE:286078 ear 3' read A
BG928566.1 connective tissue P
BI053381.1 placenta P
BI055451.1 placenta P
BI056072.1 placenta P
BI063467.1 uterus P
BI063831.1 uterus P
BI063841.1 uterus P
N75131.1 Clone IMAGE:284508 brain 5' read
BI010180.1 uncharacterized tissue P
BG961383.1 intestine P
ES312542.1 skin 5' read A
AU185423.1 Clone B01924-008 uncharacterized tissue P
BI856463.1 Clone IMAGE:5394466 mammary gland 5' read A
BI860233.1 Clone IMAGE:5395737 mammary gland 5' read P
CU455962.1 skin P
CU444227.1 skin P
CU449534.1 skin P
CU454215.1 skin P
BM126119.1 Clone IMAGE:5675711 pancreas 3' read A
BM353244.1 pancreas 5' read P
BM353398.1 pancreas 5' read P
BM468087.1 Clone IMAGE:5577958 skin 5' read P
BM473215.1 Clone IMAGE:5519736 uterus 5' read
BM474560.1 Clone IMAGE:5521783 uterus 5' read P
BM682547.1 Clone UI-E-EJ0-aih-a-21-0-UI eye 3' read PA
BM691019.1 Clone UI-E-CI1-aba-f-08-0-UI eye 5' read P
W52304.1 Clone IMAGE:325454 skin 5' read P
BM726114.1 Clone UI-E-EJ0-aih-a-21-0-UI eye 5' read P
W56703.1 Clone IMAGE:340632 heart 5' read
R29730.1 Clone F1-1255D liver 5' read
BM800691.1 Clone IMAGE:5535228 uterus 5' read P
BM826583.1 Clone S22SNU16n1-109-C08 ascites 5' read P
BM842079.1 Clone S12SNU216-56-A12 lymph node 5' read A
BM888491.1 Clone 105626 eye 5' read P
BM921219.1 Clone IMAGE:5752567 mixed 5' read P
BM999270.1 Clone IMAGE:5882197 lung 3' read A
BQ000720.1 Clone IMAGE:5891983 connective tissue 3' read PA
BY999438.1 Clone cp1494 eye 3' read A
BQ018993.1 Clone IMAGE:5824346 connective tissue 3' read PA
BY999760.1 Clone cp2006 eye 3' read
BQ228712.1 Clone IMAGE:6069868 uncharacterized tissue 5' read P
BQ373265.1 prostate
BQ373268.1 prostate
BQ373269.1 prostate P
AA025637.1 Clone IMAGE:366261 heart 5' read
AA025638.1 Clone IMAGE:366261 heart 3' read
BQ431591.1 Clone IMAGE:6156216 uterus 5' read P
BQ440001.1 Clone IMAGE:6158663 skin 5' read PA
AA033583.1 Clone IMAGE:471167 uterus 5' read P
AA033584.1 Clone IMAGE:471167 uterus 3' read A
AA035172.1 Clone IMAGE:471896 uterus 3' read P
AA043426.1 Clone IMAGE:486689 uterus 5' read P
AA043427.1 Clone IMAGE:486689 uterus 3' read P
BQ950039.1 Clone IMAGE:6201879 nerve 5' read
BU184427.1 Clone IMAGE:6171111 eye 5' read P
BU509638.1 Clone IMAGE:6504258 uterus 5' read P
BU149997.1 Clone IMAGE:6185505 ganglia 5' read P
BU533202.1 Clone IMAGE:6559441 mixed 5' read A
BU535791.1 Clone IMAGE:6563528 mixed 5' read A
AA148635.1 Clone IMAGE:503059 uterus 5' read P
AA148636.1 Clone IMAGE:503059 uterus 3' read
AA164764.1 Clone IMAGE:595168 ovary 5' read P
AA164765.1 Clone IMAGE:595168 ovary 3' read A
BU630185.1 Clone UI-H-FE1-bdt-e-10-0-UI bone 3' read PA
BU632058.1 Clone UI-H-FE1-bea-o-05-0-UI bone 3' read PA
AA215808.1 Clone IMAGE:683707 lymph node 5' read P
AA229414.1 Clone IMAGE:1011311 prostate
BU674700.1 Clone UI-CF-DU0-aac-l-02-0-UI lung 3' read A
BU679392.1 Clone UI-CF-DU1-aau-g-02-0-UI lung 3' read PA
BU726340.1 Clone UI-E-CI1-aba-f-08-0-UI eye 3' read A
BU943532.1 Clone IMAGE:6723457 mixed 5' read
AA249061.1 heart 5' read P
CA394204.1 Clone cs48g05 eye 5' read P
CA412624.1 Clone UI-H-EZ0-bam-f-04-0-UI bone 3' read A
AA296816.1 vascular 5' read P
AA297001.1 adipose tissue 5' read P
AA298883.1 pancreas 5' read P
AA298894.1 pancreas 5' read P
AA361957.1 uncharacterized tissue 5' read P
AA383998.1 thyroid 5' read P
AA385594.1 thyroid 5' read P
AA290863.1 Clone IMAGE:713558 ovary 3' read A
AA291045.1 Clone IMAGE:713558 ovary 5' read P
CA942671.1 Clone IMAGE:6607332 pancreas 3' read A
CA942909.1 Clone IMAGE:6607332 pancreas 5' read P
AA428341.1 Clone IMAGE:769673 ovary 3' read A
AA447611.1 Clone IMAGE:782703 testis 3' read A
AA448110.1 Clone IMAGE:782703 testis 5' read
AA599696.1 Clone IMAGE:1069969 kidney 3' read A
AA634453.1 Clone IMAGE:744240 testis 3' read A
AA709149.1 Clone IMAGE:385016 heart 3' read
AA768023.1 Clone IMAGE:1316668 lymph node 3' read
AA769090.1 Clone IMAGE:1318030 lymph node 3' read
AA814881.1 Clone IMAGE:1318106 lymph node 3' read
AA872018.1 Clone IMAGE:1475655 uncharacterized tissue 3' read A
AA878521.1 Clone IMAGE:1492608 kidney 3' read A
AA932620.1 Clone IMAGE:1570711 lung 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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