ONLINE DATABASE SEARCH -
DMID-LS-137-MEMO
1.
60020 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Novel human, feline, chicken and other animal interferons and their
antiproliferative and antiviral uses
Pestka, Sidney and Krause, Christopher D
PATENT: WO
2006099451 ISSUE DATE: 20060921
APPLICATION: 2006 PP:
156pp.
ASSIGNEE: (University of
Medicine & Dentistry of New Jersey, USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
2.
60021 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
4-Aminoquinoline compounds for treating virus-related
conditions
Olivo, Paul D, Buscher, Benjamin A, Dyall, Julie, Jocket-Balsarotti,
Jennifer I, O'Guin, Andrew K, Roth, Robert M, Zhou, Yi, Franklin, Gary W, and
Starkey, Gale W
PATENT: WO 2006121767 ISSUE DATE: 20061116
APPLICATION: 2006 PP:
93pp.
ASSIGNEE: (Apath, LLC
USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
3.
60022 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Small molecule inhibitors against West Nile virus
replication
Gu, Baohua, Block, Tim, and Cuconati, Andy
PATENT: WO
2007005541 ISSUE DATE: 20070111
APPLICATION: 2006 PP:
81pp.
ASSIGNEE: (Philadelphia
Health & Education Corporation, d b a Drexel University College of Medicine
USA
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HYPERLINK:
4.
60023 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Preparation of 2,3,4,9-tetrahydro-1H-b-carbolines for treatment of dengue
fever, yellow fever, West Nile virus, and hepatitis C virus
infection
Gudmundsson, Kristjan
PATENT: WO
2007002051 ISSUE DATE: 20070104
APPLICATION: 2006 PP:
53pp.
ASSIGNEE: (Smithkline
Beecham Corporation, USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
5.
60024 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Yellow Fever: A Disease that Has Yet to be Conquered
Barrett Alan D T and Higgs Stephen
Annu Rev Entomol 2007.
52: 209-29.
View Data on the NIAID Therapeutics Website
HYPERLINK:
6.
60025 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Viral and cellular determinants involved in hepadnaviral
entry
Glebe Dieter and Urban Stephan
World J Gastroenterol 2007.
13(1): 22-38.
View Data on the NIAID Therapeutics Website
HYPERLINK:
7.
60026 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Inhibitors of Epstein-Barr virus nuclear antigen 1, screening methods,
and therapeutic use
Kieff, Elliott and Kang, Myung-Soo
PATENT: WO
2007002587 ISSUE DATE: 20070104
APPLICATION: 2006 PP:
66pp.
ASSIGNEE: (The Brigham and
Women's Hospital, Inc. USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
8.
60027 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Reactivation of Herpes Simplex Virus Type 1 and Varicella-Zoster Virus
and Therapeutic Effects of Combination Therapy With Prednisolone and
Valacyclovir in Patients With Bell's Palsy
Kawaguchi, Kazuhiro, Inamura, Hiroo, Abe, Yasuhiro, Koshu, Hidehiro,
Takashita, Emi, Muraki, Yasushi, Matsuzaki, Yoko, Nishimura, Hidekazu, Ishikawa,
Hitoshi, Fukao, Akira, Hongo, Seiji, and Aoyagi, Masaru
Laryngoscope 2007.
117(1): 147-156
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HYPERLINK:
9.
60028 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Lethal infection of K18-hACE2 mice infected with severe acute respiratory
syndrome coronavirus
McCray, Paul B Jr, Pewe, Lecia, Wohlford-Lenane, Christine, Hickey,
Melissa, Manzel, Lori, Shi, Lei, Netland, Jason, Jia, Hong Peng, Halabi, Carmen,
Sigmund, Curt D, Meyerholz, David K, Kirby, Patricia, Look, Dwight C, and
Perlman, Stanley
Journal of Virology 2007.
81(2): 813-821
View Data on the NIAID Therapeutics Website
HYPERLINK:
10.
60029 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Severe acute respiratory syndrome coronavirus infection of mice
transgenic for the human Angiotensin-converting enzyme 2 virus
receptor
Tseng Chien-Te K, Huang Cheng, Newman Patrick, Wang Nan, Narayanan
Krishna, Watts Douglas M, Makino Shinji, Packard Michelle M, Zaki Sherif R, Chan
Teh-Sheng, and Peters Clarence J
J Virol 2007. 81(3):
1162-73.
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HYPERLINK:
11.
60030 DMID-LS-137;
WOS-DMID-1/29/2007
Naturally-occurring hepatitis C virus protease variants: implications for
resistance to new antivirals
Lopez-Labradorl, FX, Moya, A, and Gonzalez-Candelas,
F
JOURNAL OF CLINICAL VIROLOGY: J. Clin. Virol 2006. 36: S35-1
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000240804100140
12.
60031 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Low-toxicity and
long-circulating analogs of human interferon-a modified with PEG for treating
cancer and viral infection
Villarete, Lorelie H and Liu, Chih-Ping
PATENT: WO
2007002233 ISSUE DATE: 20070104
APPLICATION: 2006 PP:
72pp.
ASSIGNEE: (Pepgen
Corporation, USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
13.
60032 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Methods of use of non-ATP competitive tyrosine kinase inhibitors to treat
pathogenic infection
Kalman, Daniel and Bornmann, William Gerard
PATENT: WO
2007002441 ISSUE DATE: 20070104
APPLICATION: 2006 PP:
85pp.
ASSIGNEE: (Emory University,
USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
14.
60033 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: From anti-pestivirus
to anti-hepatitis C virus activity
Puerstinger, Gerhard, Paeshuyse, Jan, De Clercq, Erik, and Neyts,
Johan
Bioorganic & Medicinal
Chemistry Letters 2007.
17(2): 390-393
View Data on the NIAID Therapeutics Website
HYPERLINK:
15.
60034 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Preparation of quinolones as antivirals
Kumar, Dange Vijay and Rai, Roopa
PATENT: WO
2007005779 ISSUE DATE: 20070111
APPLICATION: 2006 PP:
50pp.
ASSIGNEE: (Virobay, Inc.
USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
16.
60035 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Preparation of prolyl peptides as HCV inhibitors
Graupe, Michael, Link, John O, and Venkataramani,
Chandrasekar
PATENT: WO
2007005838 ISSUE DATE: 20070111
APPLICATION: 2006 PP:
87pp.
ASSIGNEE: (Virobay, Inc.
USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
17.
60036 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Preparation of amino acid amides as non-nucleoside anti-hepacivirus
agents
Boyd, Vincent A, Cameron, Dale R, Jia, Qi, Sgarbi, Paulo WM, and
Wacowich-Sgarbi, Shirley A
PATENT: WO
2007002639 ISSUE DATE: 20070104
APPLICATION: 2006 PP:
303pp.
ASSIGNEE: (Migenix Inc.,
Can.
View Data on the NIAID Therapeutics Website
HYPERLINK:
18.
60037 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Preparation of pyrazolopyridinecarboxamides as inhibitors of
beta-adrenergic receptor kinase 1
Steinhagen, Henning, Huber, Jochen, Ritter, Kurt, Pirard, Bernard,
Bjergarde, Kirsten, Patek, Marcel, Smrcina, Martin, and Wei,
Linli
PATENT: WO
2007000241 ISSUE DATE: 20070104
APPLICATION: 2006 PP:
71pp.
ASSIGNEE: (Sanofi-Aventis Deutschland G.m.b.H.,
Germany
View Data on the NIAID Therapeutics Website
HYPERLINK:
19.
60038 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
Manufacture of anti-HCV drugs with Fusarium
Aoki, Masahiro, Nagahashi, Yoshie, Kato, Hideyuki, Ito, Tatsuya,
Masubuchi, Miyako, and Okuda, Toru
PATENT: WO
2007000994 ISSUE DATE: 20070104
APPLICATION: 2006 PP:
81pp.
ASSIGNEE: (Chugai Seiyaku
Kabushiki Kaisha, Japan
View Data on the NIAID Therapeutics Website
HYPERLINK:
20.
60039 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
In vitro infection of immortalized primary hepatocytes by HCV genotype 4a
and inhibition of virus replication by cyclosporin
El-Farrash Mohamed A, Aly Hussein H, Watashi Koichi, Hijikata Makoto,
Egawa Hiroto, and Shimotohno Kunitada
Microbiol Immunol 2007.
51(1): 127-33.
View Data on the NIAID Therapeutics Website
HYPERLINK:
21.
60040 DMID-LS-137;
WOS-DMID-1/29/2007
The role of peginterferon alpha-2a (40kD) plus ribavirin in the
management of chronic hepatitis C mono-infection
Simpson, D
and Curran, MP
DISEASE MANAGEMENT & HEALTH OUTCOMES: Dis. Manag. Health Outcomes
2006. 14(5): 303-320,
18
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000242720100005
22.
60041 DMID-LS-137;
SCIFINDER-DMID-1/29/2007
A cell-based, high-throughput screen for small molecule regulators of
hepatitis C virus replication
Kim Sun Suk, Peng Lee F, Lin Wenyu, Choe Won-Hyeok, Sakamoto Naoya,
Schreiber Stuart L, and Chung Raymond T
Gastroenterology 2007.
132(1): 311-20.
View Data on the NIAID Therapeutics Website
HYPERLINK:
23.
60042 DMID-LS-137;
WOS-DMID-1/29/2007
HBV drug resistance
Locarnini, S
ANTIVIRAL THERAPY: Antivir.
Ther 2006. 11(5):
P4-1
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239984700020
24.
60043 DMID-LS-137;
WOS-DMID-1/29/2007
Tenofovir disoproxil fumarate (TDF) and adefovir dipivoxil (ADV) are
effective in chronic hepatitis B virus (HBV) infection in subjects who are
co-infected with HIV: HBV and HIV drug resistance results of ACTG Protocol
A5127
Johnson, VA, Hazelwood, JD, Andersen, J, Miller, AB, Liu, T,
Alston-Smith, B, Brosgart, CL, Rooney, JF, Polsky, B, and Peters,
MG
ANTIVIRAL THERAPY: Antivir. Ther 2006. 11(5): S11-1
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239984700029
25.
60044 DMID-LS-137;
WOS-DMID-1/29/2007
Ribavirin treatment, but not interferon pharmacokinetics, is associated
with suppression of viral rebounds during high dose interferon-alpha-2a therapy
of hepatitis C infection
Frost, SDW, Ruffini, L, Richman, DD, and Lake-Bakaar,
G
ANTIVIRAL THERAPY: Antivir. Ther 2006. 11(5): S13-1
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239984700031
26.
60045 DMID-LS-137;
WOS-DMID-1/29/2007
Aberrant innate immune response in lethal infection of macaques with the
1918 influenza virus
Kobasa, D, Jones, SM, Shinya, K, Kash, JC, Copps, J, Ebihara, H, Hatta,
Y, Kim, JH, Halfmann, P, Hatta, M, Feldmann, F, Alimonti, JB, Fernando, L, Li,
Y, Katze, MG, Feldmann, H, and Kawaoka, Y
NATURE: Nature
2007. 445(7125):
319-323, 5
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243504700046
27.
60046 DMID-LS-137;
WOS-DMID-1/29/2007
Docking and binding mode analysis of aryl diketoacids (ADK) at the active
site of HCV RNA-dependent RNA polymerase
Kim, J and Chong, Y
MOLECULAR SIMULATION: Mol. Simul 2006. 32(14): 1131-1138,
8
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243257900002
28.
60047 DMID-LS-137;
WOS-DMID-1/29/2007
Cytokine-activated natural killer cells exert direct killing of hepatoma
cells harboring hepatitis C virus replicons
Larkin, J, Bost, A, Glass, JI, and Tan, SL
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH: J. Interferon Cytokine Res
2006. 26(12): 854-865,
12
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243076600002
29.
60048 DMID-LS-137;
WOS-DMID-1/29/2007
Prediction of binding for a kind of non-peptic HCVNS3 serine protease
inhibitors from plants by molecular docking and MM-PBSA method
Li, XD, Zhang, W, Qiao, XB, and Xu, XJ
BIOORGANIC & MEDICINAL CHEMISTRY: Bioorg. Med. Chem 2007. 15(1): 220-226, 7
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243087200019
30.
60049 DMID-LS-137;
WOS-DMID-1/29/2007
Antiviral activity of proteasome inhibitors in herpes simplex virus-1
infection: role of nuclear factor-kappa B
La Frazia, S, Amici, C, and Sontoro, MG
ANTIVIRAL THERAPY: Antivir. Ther 2006. 11(8): 995-1004,
10
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243183100005
31.
60050 DMID-LS-137;
WOS-DMID-1/29/2007
Hepatitis C virus (HCV) NS5B nonnucleoside inhibitors specifically block
single-stranded viral RNA synthesis catalyzed by HCV replication complexes in
vitro
Yang, WG, Sun, YN, Phadke, A, Deshpande, M, and Huang,
MJ
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY: Antimicrob. Agents Chemother
2007. 51( 1): 338-342,
5
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243214200044
32.
60051 DMID-LS-137;
WOS-DMID-1/29/2007
Hydantoin derivatives of L- and D-amino acids: Synthesis and evaluation
of their antiviral and antitumoral activity
Rajic, Z, Zorc, B, Raic-Malic, S, Ester, K, Kralj, M, Pavelic, K,
Balzarini, J, De Clercq, E, and Mintas, M
MOLECULES: Molecules 2006.
11(11): 12
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000242971700002
33.
60052 DMID-LS-137;
WOS-DMID-1/29/2007
N-1-substituted thymine derivatives as mitochondrial thymidine kinase
(TK-2) inhibitors
Hernandez, AI, Familiar, O, Negri, A, Rodriguez-Barrios, F, Gago, F,
Karlsson, A, Camarasa, MJ, Balzarini, J, and Perez-Perez,
MJ
JOURNAL OF MEDICINAL CHEMISTRY: J. Med. Chem 2006. 49(26): 7766-7773,
8
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000242974100022
34.
60053 DMID-LS-137;
WOS-DMID-1/29/2007
Resveratrol inhibition of varicella-zoster virus replication in
vitro
Docherty, JJ, Sweet, TJ, Bailey, E, Faith, SA, and Booth,
T
ANTIVIRAL RESEARCH: Antiviral Res 2006. 72(3): 171-177, 7
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000242735800002
35.
60054 DMID-LS-137;
WOS-DMID-1/29/2007
Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in
rats
Chang, YW, Yeh, TK, Lin, KT, Chen, WC, Yao, HT, Lan, SJ, Wu, YS, Hsieh,
HP, Chen, CM, and Chen, CT
JOURNAL OF FOOD AND DRUG ANALYSIS: J. Food Drug Anal 2006. 14(4): 329-333, 5
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243186700003
36.
60055 DMID-LS-137;
WOS-DMID-1/29/2007
Indomethacin has a potent antiviral activity against SARS
coronavirus
Amici, C, Di Caro, A, Ciucci, A, Chioppa, L, Castilletti, C, Martella, V,
Decaro, N, Buonavoglia, C, Capobianchi, MR, and Santoro,
MG
ANTIVIRAL THERAPY: Antivir. Ther 2006. 11(8): 1021-1030,
10
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243183100008
37.
60056 DMID-LS-137;
WOS-DMID-1/29/2007
Inhibitory effect of gamma interferon on BK virus gene expression and
replication
Abend, JR, Low, JA, and Imperiale, MJ
JOURNAL OF VIROLOGY: J. Virol 2007. 81(1): 272-279, 8
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000242958600025
38.
60057 DMID-LS-137;
PUBMED-DMID-1/29/2007
In vitro activity evaluation of Parkia pendula seed lectin against human
cytomegalovirus and herpes virus 6
Favacho, AR, Cintra, EA, Coelho, LC, and Linhares,
MI
Biologicals 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
39.
60058 DMID-LS-137;
PUBMED-DMID-1/29/2007
Antiviral Resistance and the Control of Pandemic
Influenza
Lipsitch, M, Cohen, T, Murray, M, and Levin, BR
PLoS Med 2007. 4(1):
e15
View Data on the NIAID Therapeutics Website
HYPERLINK:
40.
60059 DMID-LS-137;
PUBMED-DMID-1/29/2007
Bicyclol for chronic hepatitis C
Yang, X, Zhuo, Q, Wu, T, and Liu, G
Cochrane Database Syst Rev 2007.(1):
CD004994
View Data on the NIAID Therapeutics Website
HYPERLINK:
41.
60060 DMID-LS-137;
PUBMED-DMID-1/29/2007
Neuraminidase inhibitors for preventing and treating influenza in
children
Matheson, Nj, Harnden, A, Perera, R, Sheikh, A, and Symmonds-Abrahams,
M
Cochrane Database Syst Rev 2007.(1):
CD002744
View Data on the NIAID Therapeutics Website
HYPERLINK:
42.
60061 DMID-LS-137;
PUBMED-DMID-1/29/2007
Design, synthesis, and preliminary in vitro and in silico antiviral
activity of [4,7]phenantrolines and 1-oxo-1,4-dihydro-[4,7]phenantrolines
against single-stranded positive-sense RNA genome viruses
Carta, A, Loriga, M, Paglietti, G, Ferrone, M, Fermeglia, M, Pricl, S,
Sanna, T, Ibba, C, La, Colla P, and Loddo, R
Bioorg Med Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
43.
60062 DMID-LS-137;
PUBMED-DMID-1/29/2007
Five years of progress on cyclin-dependent kinases and other cellular
proteins as potential targets for antiviral drugs
Schang, LM, St, Vincent MR, and Lacasse, JJ
Antivir Chem Chemother 2006.
17(6): 293-320
View Data on the NIAID Therapeutics Website
HYPERLINK:
44.
60063 DMID-LS-137;
PUBMED-DMID-1/29/2007
Inhibition of hepatitis B virus replication by shRNAs in stably HBV
expressed HEPG2 2.2.15 cell lines
Kayhan, H, Karatayli, E, Turkyilmaz, AR, Sahin, F, Yurdaydin, C, and
Bozdayi, AM
Arch Virol 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
45.
60064 DMID-LS-137;
PUBMED-DMID-1/29/2007
West Nile virus
Kramer, LD, Li, J, and Shi, PY
Lancet Neurol 2007.
6(2): 171-81
View Data on the NIAID Therapeutics Website
HYPERLINK:
46.
60065 DMID-LS-137;
PUBMED-DMID-1/29/2007
Antiviral activity of berberine and related compounds against human
cytomegalovirus
Hayashi, K, Minoda, K, Nagaoka, Y, Hayashi, T, and Uesato,
S
Bioorg Med Chem Lett 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
47.
60066 DMID-LS-137;
PUBMED-DMID-1/29/2007
Pegylation of IFN-alpha and antiviral activity
Boulestin, A, Kamar, N, Sandres-Saune, K, Alric, L, Vinel, JP, Rostaing,
L, and Izopet, J
J Interferon Cytokine Res 2006. 26(12): 849-53
View Data on the NIAID Therapeutics Website
HYPERLINK:
48.
60067 DMID-LS-137;
PUBMED-DMID-1/29/2007
From actually toxic to highly specific--novel drugs against
poxviruses
Sliva, K and Schnierle, B
Virol J 2007. 4:
8
View Data on the NIAID Therapeutics Website
HYPERLINK:
49.
60068 DMID-LS-137;
PUBMED-DMID-1/29/2007
N-Long-chain Monoacylated Derivatives of 2,6-Diaminopyridine with
Antiviral Activity
Mibu, N, Yokomizo, K, Kashige, N, Miake, F, Miyata, T, Uyeda, M, and
Sumoto, K
Chem Pharm Bull (Tokyo) 2007. 55(1): 111-4