Colombero D, Teicher E, Ludo S; International Conference on AIDS.
Int Conf AIDS. 2000 Jul 9-14; 13: abstract no. TuPeB3153.
D. Colombero, Rodriguez 1215, Rosario 2000, Argentina, Tel.: +54 341 424 8045, Fax: +54 341 424 8045, E-mail: caici@citynet.net.ar
Background: immune recovery vitritis (IRV) has been reported in eyes with cytomegalovirus retinitis (CMVR) in patients with elevated CD4 cell counts on highly active antiretroviral therapy (HAART). However is considered favourable, long term results are not known. The purpose of this study was to determine the visual significance and long term complications related to IRV in patients with CMVR on HAART. Methods: A cohort of eight patients with IRV were followed for at least 12 months. Results: The mean age of the patients was 35.6 years. CD4 count at the time of IRV was 106 cells/m l. Four patients had bilateral vitreous inflammation. None of the patients had recurrence of the CMVR during the follow up examinations. Relate findings were: cystoid macular edema, epiretinal membrane, posterior subcapsular cataract, optic disc edema, vitreo-macular traction, optic disc neovascularization, vitreous hemorrhage and retinal detachment. Visual acuity improved in only 4 eyes, and 4 eyes were treated with subtenon steroids. Conclusions: IRV is a frequent complication in patients with healed CMVR, increased CD4 count and HAART. Although it is not related to severe complications, it may persist for months and produce a variable degree of visual disability.
Publication Types:
Keywords:
- Antiretroviral Therapy, Highly Active
- CD4 Lymphocyte Count
- Cytomegalovirus Retinitis
- Epiretinal Membrane
- Humans
- Inflammation
- Macular Edema
- Papilledema
- Retinal Detachment
- Uveitis, Intermediate
- Visual Acuity
Other ID:
UI: 102239063
From Meeting Abstracts