Fong IW, Laurel M, Burford-Mason A; National Conference on Human Retroviruses and Related Infections.

Program Abstr Second Natl Conf Hum Retrovir Relat Infect Natl Conf Hum Retrovir Relat Infect 2nd 1995 Wash DC. 1995 Jan 29-Feb 2; 77.

St. Michael's Hospital, University of Toronto, Toronto, Canada.

Oral candidiasis is one of the most common infection experienced by HIV+ patients. In healthy subjects oral carriage of yeast is related to blood group O and non- secretion of blood group antigen in the saliva. In a prospective, longitudinal study over 6 months, oral carriage of yeast was determined in 106 HIV+ patients, and 35 healthy controls and correlated with blood type, secretor status (of blood group antigen) in saliva, CD4 counts. No correlation was found in HIV+ patients with blood type and secretor status.Persistent carriage of yeast and clinical thrush was correlated with low CD4 counts. The oral carriage of yeast at any time (intermittently and persistently) was significantly greater for all HIV+ patients versus controls irrespective of CD4 counts. The greater risk of oral colonization with Candida albicans may partly explain the high prevalence of thrush in HIV+ patients.

Publication Types:

• Meeting Abstracts

Keywords:

• Acquired Immunodeficiency Syndrome
• Blood Grouping and Crossmatching
• CD4 Lymphocyte Count
• Candida albicans
• Candidiasis
• Candidiasis, Oral
• HIV Infections
• HIV Seropositivity
• Humans
• Prospective Studies
• Saccharomyces cerevisiae
• Saliva

Other ID:

• 95920157

UI: 102213102

From Meeting Abstracts