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UGID:148876     UniGene Hs.130607     Homo sapiens (human)   MVK
Mevalonate kinase (MVK)
SELECTED PROTEIN SIMILARITIES
Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.
Reference ProteinSpeciesId(%)Len(aa)
NP_001107657.1 mevalonate kinase H. sapiens 100.0 395
NP_076045.1 mevalonate kinase M. musculus 85.5 394
NP_001007350.1 hypothetical protein LOC492477 D. rerio 64.2 394

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; mixed; placenta; muscle; connective tissue; heart; thymus; skin; eye; kidney; stomach; esophagus; vascular; cervix; lung; lymph; liver; mammary gland; prostate; embryonic tissue; blood; uterus; intestine; pancreas; ascites; bladder; spleen; ovary; bone; adrenal gland; adipose tissue; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24
UniSTS entry: Chr 12 A001U02
UniSTS entry: Chr 12 STS-N30046
UniSTS entry: Chr 12 RH92084
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

M88468.1 Homo sapiens mevalonate kinase mRNA, complete cds P
NM_000431.2 Homo sapiens mevalonate kinase (MVK), transcript variant 1, mRNA PA
CR622427.1 full-length cDNA clone CS0DK007YJ14 of HeLa cells Cot 25-normalized of Homo sapiens (human) P
CR622040.1 full-length cDNA clone CS0DI010YD19 of Placenta Cot 25-normalized of Homo sapiens (human) P
CR596805.1 full-length cDNA clone CS0DA001YE01 of Neuroblastoma of Homo sapiens (human)
CR593675.1 full-length cDNA clone CS0DI020YA24 of Placenta Cot 25-normalized of Homo sapiens (human) P
AB209722.1 Homo sapiens mRNA for mevalonate kinase variant protein P
BC016140.1 Homo sapiens mevalonate kinase, mRNA (cDNA clone MGC:9001 IMAGE:3921543), complete cds PA
AK315678.1 Homo sapiens cDNA, FLJ96772, Homo sapiens mevalonate kinase (mevalonic aciduria) (MVK), mRNA P
NM_001114185.1 Homo sapiens mevalonate kinase (MVK), transcript variant 2, mRNA PA

EST sequences (295)

AA911229.1 Clone IMAGE:1526798 mixed 3' read A
AI094619.1 Clone IMAGE:1670290 brain 3' read A
AI129350.1 Clone IMAGE:1712855 uterus 3' read A
BX107829.1 Clone IMAGp998K19127_;_IMAGE:126474 mixed P
R25055.1 Clone IMAGE:35200 brain 5' read
CB154792.1 Clone B2N807043-24-G11 brain 5' read P
CB150594.1 Clone C1SNU17-32-A06 cervix 5' read P
CB128440.1 Clone L11SNU354-22-D10 liver 5' read P
CB149270.1 Clone L15CKK1-44-B12 liver 5' read P
AI240786.1 Clone IMAGE:1848472 mixed 3' read A
AI240788.1 Clone IMAGE:1848457 mixed 3' read A
R35287.1 Clone IMAGE:37341 brain 5' read P
AI418441.1 Clone IMAGE:2110914 mixed 3' read A
R48759.1 Clone IMAGE:153953 mammary gland 5' read
R51202.1 Clone IMAGE:37341 brain 3' read A
AI571513.1 Clone IMAGE:2225065 pancreas 3' read A
T08969.1 Clone HIBBN03 brain 5' read P
R45394.1 Clone IMAGE:35200 brain 3' read A
R59901.1 Clone IMAGE:42583 brain 5' read P
R59902.1 Clone IMAGE:42583 brain 3' read A
R61095.1 Clone IMAGE:42643 brain 5' read P
R61818.1 Clone IMAGE:42643 brain 3' read A
CB265859.1 adipose tissue 5' read P
F00605.1 Clone 19C12 muscle P
BX333834.2 Clone CS0DD002YK22 uncharacterized tissue 5' read P
BX355400.2 Clone CS0DD006YH24 uncharacterized tissue 5' read P
BX394163.2 Clone CS0DC011YI13 uncharacterized tissue 3' read
BX394164.2 Clone CS0DC011YI13 uncharacterized tissue 5' read P
BX374865.2 Clone CS0DC004YM19 uncharacterized tissue 3' read
BX374866.2 Clone CS0DC004YM19 uncharacterized tissue 5' read
BX375059.2 Clone CS0DC007YF07 uncharacterized tissue 5' read P
BX335797.2 Clone CS0DI020YA24 placenta 3' read P
BX335798.2 Clone CS0DI020YA24 placenta 5' read P
BX358717.2 Clone CS0DI042YF24 placenta 3' read P
BX358718.2 Clone CS0DI042YF24 placenta 5' read P
BX381906.2 Clone CS0DI071YD03 placenta 3' read
BX381907.2 Clone CS0DI071YD03 placenta 5' read P
BX403362.2 Clone CS0DI020YA24 placenta 5' read P
BX403363.2 Clone CS0DI020YA24 placenta 5' read P
BX362390.1 Clone CS0DJ014YL07 blood 3' read P
BX362391.2 Clone CS0DJ014YL07 blood 5' read P
BX345094.2 Clone CS0DB004YP24 uncharacterized tissue 5' read P
BX387133.2 Clone CS0DB001YP24 uncharacterized tissue 5' read P
BX401097.2 Clone CS0DK007YJ14 cervix 5' read P
BX331017.2 Clone CS0DK007YJ14 cervix 3' read A
BX327572.2 Clone CS0DK007YJ14 cervix 5' read P
BX433900.2 Clone CS0DA001YE01 uncharacterized tissue 3' read
BX437857.2 Clone CS0DA001YE01 uncharacterized tissue 5' read
BX404403.2 Clone CL0BB028ZE10 uncharacterized tissue 5' read P
CB852388.1 Clone UI-CF-FN0-afb-g-03-0-UI lung 3' read A
AI962983.1 Clone IMAGE:2508530 uterus 3' read A
AI963831.1 Clone IMAGE:2492761 uterus 3' read A
CD171624.1 Clone IMAGE:30379015 testis 5' read P
BX457988.2 Clone CS0DA007YL14 uncharacterized tissue 5' read P
AI978817.1 Clone IMAGE:2492045 uterus 3' read A
AI991153.1 Clone IMAGE:2522371 intestine 3' read A
CD517557.1 Clone IMAGE:30407903 brain 5' read P
AW102608.1 Clone IMAGE:2602812 mixed 3' read A
AW135171.1 Clone IMAGE:2713667 mixed 3' read A
AW054841.1 Clone IMAGE:2501608 brain 3' read A
AW195909.1 Clone IMAGE:2701383 mixed 3' read A
R74065.1 Clone IMAGE:156917 mammary gland 3' read A
R74164.1 Clone IMAGE:156917 mammary gland 5' read
T15910.1 brain 3' read A
AW839963.1 uncharacterized tissue P
AW877283.1 uncharacterized tissue P
CN415008.1 embryonic tissue 5' read P
CN415005.1 embryonic tissue 5' read P
CN415006.1 embryonic tissue 5' read P
CN415007.1 embryonic tissue 5' read P
H08205.1 Clone IMAGE:45600 brain 3' read A
H08303.1 Clone IMAGE:45600 brain 5' read P
H09284.1 Clone IMAGE:46420 brain 5' read P
H09285.1 Clone IMAGE:46420 brain 3' read A
BE019046.1 Clone IMAGE:3009712 muscle 5' read
BE049236.1 Clone IMAGE:2836021 pancreas 3' read A
CV023363.1 mixed 5' read P
BP193186.1 Clone ADB01544 brain 5' read P
BP198509.1 Clone ADG09005 adrenal gland 5' read P
BP203310.1 Clone CAE05509 vascular 5' read P
BP351562.1 Clone T3R05032 esophagus 5' read P
BP261036.1 Clone HSI02310 intestine 5' read P
BP273727.1 Clone KAT10420 stomach 5' read P
BP274171.1 Clone KDN00317 kidney 5' read P
BP275253.1 Clone KDN03169 kidney 5' read P
BE294452.1 Clone IMAGE:3531281 muscle 5' read P
H28676.1 Clone IMAGE:181519 mammary gland 3' read
CK326981.1 lung P
CX762321.1 Clone IMAGE:7772585 embryonic tissue 3' read P
CX785623.1 Clone IMAGE:7480557 embryonic tissue 5' read P
CX872771.1 Clone IMAGE:7487505 embryonic tissue 5' read P
BE733171.1 Clone IMAGE:3842538 placenta 5' read P
BE733325.1 Clone IMAGE:3845048 placenta 5' read P
H39678.1 Clone IMAGE:181517 mammary gland 5' read
BE810548.1 uncharacterized tissue P
BE886719.1 Clone IMAGE:3909547 uterus 5' read P
DR002511.1 Clone TC119883 brain 5' read P
BE894789.1 Clone IMAGE:3921543 skin 5' read P
BE908295.1 Clone IMAGE:3902324 pancreas 5' read
AV730362.1 Clone HTFBMD12 brain 5' read
DR159360.1 Clone IMAGE:7968565 embryonic tissue 5' read P
AV743183.1 Clone CBFAAG03 blood 5' read A
CR988012.1 Clone RZPDp9016L1033 uncharacterized tissue 5' read P
AU117373.1 Clone HEMBA1001253 embryonic tissue 5' read P
T28816.1 brain 3' read A
AU128672.1 Clone NT2RP2003932 testis 5' read P
BF311797.1 Clone IMAGE:4126656 brain 5' read P
DA348601.1 Clone BRSSN2010500 brain 5' read P
DA198756.1 Clone BRAWH2002013 brain 5' read P
DA095022.1 Clone BRACE3004655 brain 5' read P
DA089175.1 Clone BRACE2044524 brain 5' read P
DA208309.1 Clone BRAWH2015694 brain 5' read P
DA271349.1 Clone BRCAN2025853 brain 5' read P
DA114953.1 Clone BRACE3033771 brain 5' read P
BF727240.1 Clone by18g03 eye 5' read P
DA077529.1 Clone BRACE2029898 brain 5' read P
DA386143.1 Clone BRTHA2021352 brain 5' read P
DA419088.1 Clone CD34C1000195 blood 5' read P
DA537365.1 Clone FEKID1000141 kidney 5' read P
DA505737.1 Clone FCBBF3021341 brain 5' read P
DA551893.1 Clone HCHON2001323 connective tissue 5' read P
DA696114.1 Clone NT2NE2016969 5' read P
DA357020.1 Clone BRSTN2002278 brain 5' read P
DA625313.1 Clone KIDNE2005322 kidney 5' read P
DA699349.1 Clone NT2RI2001487 5' read P
DA633438.1 Clone KIDNE2015169 kidney 5' read P
DA562081.1 Clone HEART2003439 heart 5' read P
DA369629.1 Clone BRSTN2018535 brain 5' read P
DA690102.1 Clone NT2NE2009430 5' read P
DA684498.1 Clone NT2NE2002130 5' read P
DA678789.1 Clone NHNPC2000823 uncharacterized tissue 5' read P
AU152403.1 Clone NT2RP3000875 testis 3' read A
DA759030.1 Clone NT2RP8007196 testis 5' read P
DB003656.1 Clone TBAES2006185 mammary gland 5' read P
DB010269.1 Clone TCOLN2001242 intestine 5' read P
DB038455.1 Clone TESTI2024728 testis 5' read P
BF435745.1 Clone IMAGE:3268187 mixed 3' read A
BF436195.1 Clone IMAGE:3268527 mixed 3' read A
DB048024.1 Clone TESTI2036972 testis 5' read P
DA753532.1 Clone NT2RP7019766 testis 5' read P
DB030205.1 Clone TESTI2013678 testis 5' read
BF510583.1 Clone IMAGE:3087680 uncharacterized tissue 3' read PA
BF569885.1 Clone IMAGE:4310262 kidney 5' read P
BF570377.1 Clone IMAGE:4310262 kidney 3' read
DA841697.1 Clone PLACE6008914 placenta 5' read P
DB040147.1 Clone TESTI2026858 testis 5' read P
BF793986.1 Clone IMAGE:4346767 adrenal gland 5' read P
DB185342.1 Clone TLIVE2005007 liver 5' read P
DB050183.1 Clone TESTI2039666 testis 5' read P
DB124736.1 Clone THYMU2034113 thymus 5' read P
DB124757.1 Clone THYMU2034137 thymus 5' read P
DB089765.1 Clone TESTI4038458 testis 5' read P
DB174835.1 Clone TKIDN2010871 kidney 5' read P
BF764628.1 intestine
BF913211.1 uterus
BF874341.1 lung P
BF876808.1 lung
BG171117.1 Clone IMAGE:4427107 kidney 5' read P
BG171177.1 Clone IMAGE:4427054 kidney 5' read A
DB483159.1 Clone H023096G17 brain 5' read P
DB444858.1 Clone H013017G02 testis 5' read P
DB522841.1 Clone H013077G08 testis 3' read A
DB552054.1 Clone H023096G17 brain 3' read A
DB509820.1 Clone H013017G02 testis 3' read A
DB457371.1 Clone H013077G08 testis 5' read P
AL547123.3 Clone CS0DI010YD19 placenta 5' read P
N30046.1 Clone IMAGE:258570 placenta 3' read A
AL572197.3 Clone CS0DI010YD19 placenta 3' read P
BG285763.1 Clone IMAGE:4498590 bladder 5' read
BG329440.1 Clone IMAGE:4558246 eye 5' read P
N40752.1 Clone IMAGE:258570 placenta 5' read
BF172453.1 blood
BG474232.1 Clone IMAGE:4648380 eye 5' read P
DT217479.1 brain P
BG674791.1 Clone IMAGE:4746292 skin 5' read P
BG677969.1 Clone IMAGE:4750387 skin 5' read P
BG679595.1 Clone IMAGE:4752443 skin 5' read P
BG741000.1 Clone IMAGE:4779892 skin 5' read P
BG743593.1 Clone IMAGE:4779082 skin 5' read P
BG752067.1 Clone IMAGE:4875732 eye 5' read
BG825730.1 Clone IMAGE:4900091 muscle 5' read P
BG697048.1 Clone IMAGE:4803444 skin 5' read
BG719807.1 Clone IMAGE:4823523 testis 5' read P
BJ994574.1 Clone hmft-0559 liver 5' read P
BJ994613.1 Clone hmft-0647 liver 5' read P
BJ994614.1 Clone hmft-0647 liver 3' read
BG722361.1 Clone IMAGE:4825861 testis 5' read P
BI253920.1 Clone IMAGE:5113708 cervix 5' read P
BI334020.1 Clone IMAGE:5139484 cervix 5' read P
BI335076.1 Clone IMAGE:5141254 cervix 5' read P
DC296781.1 Clone CD34C3000471 blood 5' read P
DC297634.1 Clone 3NB692002462 uncharacterized tissue 5' read P
DC366241.1 Clone NT2NE2011384 5' read P
DC318779.1 Clone BRASW1000089 brain 5' read P
DC399571.1 Clone TESTI2049949 testis 5' read P
DC421549.1 Clone UTERU2028183 uterus 5' read P
DC419275.1 Clone TSTOM2002209 stomach 5' read P
DC397449.1 Clone TESTI2028819 testis 5' read P
DC386246.1 Clone SKNMC2003112 brain 5' read P
DC398052.1 Clone TESTI2034648 testis 5' read P
DC365586.1 Clone NT2NE2001602 5' read P
DC366059.1 Clone NT2NE2008679 5' read P
BI520227.1 Clone IMAGE:5163378 brain 5' read P
DC327920.1 Clone BRCAN2027778 brain 5' read P
DC315929.1 Clone BRAMY2036219 brain 5' read P
DC305854.1 Clone BRACE2042553 brain 5' read P
BI552525.1 Clone IMAGE:5274104 brain 5' read P
BI753669.1 Clone IMAGE:5193905 brain 5' read P
BI763903.1 Clone IMAGE:5189993 mixed 5' read
BI831953.1 Clone IMAGE:5168337 brain 5' read P
BM042389.1 Clone IMAGE:5557081 skin 5' read P
BM042800.1 Clone IMAGE:5557081 skin 3' read
BM043887.1 Clone IMAGE:5446389 prostate 5' read P
BM044080.1 Clone IMAGE:5446621 prostate 5' read P
BM047342.1 Clone IMAGE:5456798 prostate 5' read P
BM048234.1 Clone IMAGE:5455780 prostate 5' read
BM049852.1 Clone IMAGE:5450115 prostate 5' read P
BM050399.1 Clone IMAGE:5423459 eye 5' read P
BM563414.1 Clone IMAGE:5743987 brain 5' read P
BM563996.1 Clone IMAGE:5484608 blood 5' read P
BM671243.1 Clone UI-E-CQ1-agc-b-03-0-UI brain 3' read A
BM699751.1 Clone UI-E-DW1-agz-g-24-0-UI eye 5' read P
BM705653.1 Clone UI-E-DW0-agi-m-24-0-UI eye 5' read P
BM710081.1 Clone UI-E-CQ1-agc-b-03-0-UI brain 5' read
BM803289.1 Clone IMAGE:5573937 intestine 5' read P
BM792810.1 Clone S22SNU16n1-34-E08 ascites 5' read P
BM796096.1 Clone S22SNU16n1-51-H11 ascites 5' read P
BM824000.1 Clone S22SNU16n1-84-F06 ascites 5' read P
BM848139.1 Clone S13KMS5-48-C09 stomach 5' read P
BM848256.1 Clone S13KMS5-49-F12 stomach 5' read P
BM909403.1 Clone IMAGE:5433976 lymph 5' read P
BM914226.1 Clone IMAGE:5479100 brain 5' read P
BM918165.1 Clone IMAGE:5485548 blood 5' read P
BM923433.1 Clone IMAGE:5759050 mixed 5' read P
BM974416.1 Clone UI-CF-EC1-aca-d-07-0-UI lung 3' read A
BQ013685.1 Clone UI-1-BC1p-ala-d-09-0-UI placenta 3' read A
BQ055274.1 Clone IMAGE:5807424 lymph 5' read P
BQ056910.1 Clone IMAGE:5809359 lymph 5' read P
BQ057120.1 Clone IMAGE:5812301 lymph 5' read P
BQ057978.1 Clone IMAGE:5813756 lymph 5' read P
BQ058708.1 Clone IMAGE:5814618 lymph 5' read P
BQ061505.1 Clone IMAGE:5920961 lymph 5' read P
BQ061597.1 Clone IMAGE:5921068 lymph 5' read P
BQ062266.1 Clone IMAGE:5923718 lymph 5' read P
BQ063616.1 Clone IMAGE:5925242 lymph 5' read P
BQ063665.1 Clone IMAGE:5925298 lymph 5' read P
BQ066678.1 Clone IMAGE:5931345 lymph 5' read P
BQ067206.1 Clone IMAGE:5751583 mixed 5' read P
BQ213233.1 Clone IMAGE:6064879 skin 5' read P
BQ218740.1 Clone IMAGE:5769480 brain 5' read P
BQ642652.1 Clone IMAGE:6292607 lymph 5' read P
BQ677563.1 Clone IMAGE:6265331 skin 5' read P
BQ679577.1 Clone IMAGE:6258730 skin 5' read P
BQ683261.1 Clone IMAGE:6261204 skin 5' read P
BQ686176.1 Clone IMAGE:6209230 pancreas 5' read P
BQ709248.1 Clone IMAGE:6214194 spleen 5' read P
BG056052.1 Clone IMAGE:4171176 brain 3' read A
BQ891718.1 Clone IMAGE:6380159 prostate 5' read P
BQ919058.1 Clone IMAGE:6384001 prostate 5' read P
BU517160.1 Clone IMAGE:6514713 uterus 5' read P
BU500954.1 Clone IMAGE:6337599 eye 5' read P
BU148423.1 Clone IMAGE:6380899 prostate 5' read P
BU541281.1 Clone IMAGE:6572937 prostate 5' read P
BU543288.1 Clone IMAGE:6575318 prostate 5' read P
BU168679.1 Clone IMAGE:6266938 skin 5' read P
W28959.1 eye P
T61822.1 Clone IMAGE:78983 liver 3' read A
BU552526.1 Clone IMAGE:6576319 prostate 5' read P
T72164.1 Clone IMAGE:85877 liver 3' read
BU678260.1 Clone UI-CF-EC0-abi-c-09-0-UI lung 3' read A
T72318.1 Clone IMAGE:85877 liver 5' read
BU681971.1 Clone UI-CF-EC1-ach-m-14-0-UI lung 3' read A
BU734936.1 Clone UI-E-DW0-agi-m-24-0-UI eye 3' read A
BU737571.1 Clone UI-E-DW1-agz-g-24-0-UI eye 3' read A
BU849724.1 Clone IMAGE:6598395 ovary 5' read P
BU859119.1 Clone IMAGE:6649937 ovary 5' read P
CA426742.1 Clone UI-H-FE1-bei-i-07-0-UI bone 3' read A
CA433978.1 Clone UI-H-DF0-arp-o-22-0-UI bone 3' read A
CA434158.1 Clone UI-H-DF0-arp-o-22-0-UI bone 3' read A
CA449490.1 Clone UI-H-EI1-ayt-p-23-0-UI connective tissue 3' read A
AA351436.1 brain 5' read P
AA351756.1 brain 5' read P
AA355883.1 blood 5' read P
T81780.1 Clone IMAGE:109742 mixed 3' read
AA401084.1 Clone IMAGE:758620 embryonic tissue 3' read P
AA403187.1 Clone IMAGE:758620 embryonic tissue 5' read P
T86128.1 Clone IMAGE:114914 mixed 3' read A
T86229.1 Clone IMAGE:114914 mixed 5' read P
AA587265.1 Clone IMAGE:1089259 larynx 3' read A
AA609228.1 Clone IMAGE:1031481 testis 3' read
AA609868.1 Clone IMAGE:1031040 testis 3' read A
T96815.1 Clone IMAGE:121244 mixed 5' read P
R06715.1 Clone IMAGE:126474 mixed 5' read P
R06716.1 Clone IMAGE:126474 mixed 3' read A
AA782909.1 Clone 1375380 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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