Details of Element: Sample 7
Component of Trt

Unique Name: sam7q12
Contained in the Common BLSA Data Set ? No

Data Points (as of 09/06/98) Males Females Total
Number of Data Points 105 0 105
Number of Distinct Participants 105 0 105
Year First Collected 1960 n/a -
Year Last Collected 1977 n/a -

Type of Variable: Absolute Measure
Encoding: Continuous
Units of Measure: microunits/mL
Precision: ###.
Anticipated Range: 000. thru 999.
Masterfile Index: 123-03-19
Related Data Elements: none
Specific to this Data Element:
    Descriptive history:
    The 123 file type contains data from the tolbutamide response test (TRT). A 5 per cent solution of sodium tolbutamide in distilled water in a dose of one gram per 70 kg. body weight was administered intravenously in exactly two minutes. The tests were performed between January 1965 and June 1977 in BLSA men.

    Data collection methodology:
    Blood chemistry.

    Related protocols:
    Other blood chemistries.

    Investigators:
    Dr. Reubin Andres (primary investigator)
    GRC Box-24
    andresr@grc.nia.nih.gov
    (410)-558-8194

    Frequency of data collection:
    Every fourth or fifth visit.

    Inclusion/exclusion rules:
    No subjects previously diagnosed with Diabetes Mellitus.

    Publications using these data:
  • Swerdloff, R.S., Pozefsky, T., Tobin, J.D., Andres, R. Influence of age on the intravenous tolbutamide response test. Diabetes. 16(3): 161-70,1967.
  • Andres, R. Effect of age on the interpretation of glucose and tolbutamide tolerance tests. In: Fajans S, Sussman K, eds. Diabetes Mellitus: Diagnosis and Treatment. New York: American Diabetes Association, Inc.; 1971:115-120.
  • Andres, R. Aging and diabetes. Med Clin North Am. 55(4): 835-46,1971.
Details for this Data Type
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