BLASTP 2.2.4 [Aug-26-2002]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= SAG0508
(411 letters)
Database: nr
1,487,057 sequences; 479,114,161 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22536687|ref|NP_687538.1| beta-lactam resistance factor [Stre... 787 0.0
gi|25010623|ref|NP_735018.1| Unknown [Streptococcus agalactiae N... 787 0.0
gi|25011461|ref|NP_735856.1| unknown [Streptococcus agalactiae N... 583 e-165
gi|22537496|ref|NP_688347.1| beta-lactam resistance factor [Stre... 583 e-165
gi|24379184|ref|NP_721139.1| putative peptidoglycan branched pep... 470 e-131
gi|12746258|gb|AAK07416.1| MurN [Streptococcus pneumoniae] 457 e-127
gi|15900524|ref|NP_345128.1| beta-lactam resistance factor [Stre... 455 e-127
gi|15902585|ref|NP_358135.1| Alanine adding enzyme [Streptococcu... 452 e-126
gi|7672302|emb|CAB89538.1| MurN protein [Streptococcus pneumoniae] 452 e-126
gi|7672305|emb|CAB89540.1| MurN protein [Streptococcus pneumoniae] 450 e-125
gi|19745721|ref|NP_606857.1| putative peptidoglycan branched pep... 420 e-116
gi|15674693|ref|NP_268867.1| putative peptidoglycan branched pep... 418 e-116
gi|21909970|ref|NP_664238.1| putative peptidoglycan branched pep... 417 e-115
gi|2804352|gb|AAC46073.1| zoocin A immunity factor [Streptococcu... 361 2e-98
gi|29376659|ref|NP_815813.1| FemAB family protein [Enterococcus ... 245 1e-63
gi|23038199|ref|ZP_00070374.1| hypothetical protein [Oenococcus ... 230 3e-59
gi|23024426|ref|ZP_00063638.1| hypothetical protein [Leuconostoc... 223 6e-57
gi|23335849|ref|ZP_00121081.1| hypothetical protein [Bifidobacte... 211 2e-53
gi|23464885|ref|NP_695488.1| FemAB-like protein possibly involve... 206 6e-52
gi|23464883|ref|NP_695486.1| FemAB-like protein possibly involve... 193 5e-48
gi|23335851|ref|ZP_00121083.1| hypothetical protein [Bifidobacte... 190 4e-47
gi|23037890|ref|ZP_00070086.1| hypothetical protein [Oenococcus ... 177 3e-43
gi|23335850|ref|ZP_00121082.1| hypothetical protein [Bifidobacte... 161 2e-38
gi|23464884|ref|NP_695487.1| FemAB-like protein possibly involve... 158 2e-37
gi|4929303|gb|AAD33942.1|AF144663_1 factor essential for methici... 151 2e-35
gi|1762962|gb|AAB52984.1| FemA 150 4e-35
gi|4539616|gb|AAD22133.1|U23712_1 FEMB [Staphylococcus haemolyti... 149 1e-34
gi|27467976|ref|NP_764613.1| FemB protein [Staphylococcus epider... 141 2e-32
gi|7448859|pir||JC5326 methicillin resistance factor FEMB - Stap... 139 6e-32
gi|2462668|emb|CAA73372.1| femA [Staphylococcus hominis] 139 1e-31
gi|15924365|ref|NP_371899.1| FemB protein [Staphylococcus aureus... 137 5e-31
gi|4539614|gb|AAD22132.1|U23711_1 FEMA [Staphylococcus haemolyti... 136 6e-31
gi|3820632|gb|AAC69635.1| factor essential for methicillin resis... 136 8e-31
gi|3820624|gb|AAC69631.1| factor essential for methicillin resis... 135 2e-30
gi|119902|sp|P14304|FEMA_STAAW Factor essential for expression o... 135 2e-30
gi|21282991|ref|NP_646079.1| FemB protein [Staphylococcus aureus... 134 2e-30
gi|3820626|gb|AAC69632.1| factor essential for methicillin resis... 134 3e-30
gi|4929299|gb|AAD33940.1|AF144661_1 factor essential for methici... 134 3e-30
gi|23200368|pdb|1LRZ|A Chain A, X-Ray Crystal Structure Of Staph... 134 3e-30
gi|21282990|ref|NP_646078.1| factor essential for expression of ... 134 3e-30
gi|15924364|ref|NP_371898.1| factor essential for expression of ... 134 4e-30
gi|3820628|gb|AAC69633.1| factor essential for methicillin resis... 134 4e-30
gi|27467975|ref|NP_764612.1| methicillin resistance factor [Stap... 132 8e-30
gi|7448858|pir||JC5325 methicillin resistance factor FEMA - Stap... 132 8e-30
gi|5565907|gb|AAD45258.1|AF145332_1 methicillin resistance prote... 131 2e-29
gi|4929301|gb|AAD33941.1|AF144662_1 factor essential for methici... 130 4e-29
gi|1815618|gb|AAB41947.1| FEMA [Staphylococcus epidermidis] 130 5e-29
gi|3820630|gb|AAC69634.1| factor essential for methicillin resis... 128 2e-28
gi|5565909|gb|AAD45259.1|AF145333_1 methicillin resistance prote... 125 9e-28
gi|3820634|gb|AAC69636.1| factor essential for methicillin resis... 124 2e-27
gi|2462697|emb|CAA73373.1| femA [Staphylococcus saprophyticus] 124 3e-27
gi|15924238|ref|NP_371772.1| FmhC protein [Staphylococcus aureus... 122 1e-26
gi|21282860|ref|NP_645948.1| FmhC protein [Staphylococcus aureus... 121 2e-26
gi|4574238|gb|AAD23963.1|AF106851_2 FmhC [Staphylococcus aureus] 121 2e-26
gi|21284062|ref|NP_647150.1| fmhA protein [Staphylococcus aureus... 120 3e-26
gi|10440955|gb|AAG16879.1| lysostaphin endopeptidase resistance ... 119 8e-26
gi|15925401|ref|NP_372935.1| fmhA protein [Staphylococcus aureus... 119 8e-26
gi|27468907|ref|NP_765544.1| fmhA protein [Staphylococcus epider... 114 2e-24
gi|2257458|dbj|BAA21486.1| epr [Staphylococcus capitis] 100 6e-20
gi|2072412|gb|AAB53784.1| lysostaphin immunity factor [Staphyloc... 100 7e-20
gi|29377142|ref|NP_816296.1| FemAB family protein [Enterococcus ... 87 5e-16
gi|15675170|ref|NP_269344.1| putative antimicrobial resistance f... 87 6e-16
gi|19746137|ref|NP_607273.1| putative antimicrobial resistance f... 85 2e-15
gi|21910382|ref|NP_664650.1| putative antimicrobial resistance f... 83 8e-15
gi|21283909|ref|NP_646997.1| FmhB protein [Staphylococcus aureus... 80 6e-14
gi|15925252|ref|NP_372786.1| FmhB protein [Staphylococcus aureus... 80 6e-14
gi|21431652|gb|AAF14182.2|AF105976_1 FmhB [Staphylococcus aureus] 78 2e-13
gi|22536689|ref|NP_687540.1| murM protein, putative [Streptococc... 77 5e-13
gi|27468753|ref|NP_765390.1| FmhB protein [Staphylococcus epider... 75 2e-12
gi|24379185|ref|NP_721140.1| putative peptidoglycan branched pep... 74 3e-12
gi|12746261|gb|AAK07418.1| MurM [Streptococcus pneumoniae] 74 4e-12
gi|23037888|ref|ZP_00070084.1| hypothetical protein [Oenococcus ... 73 1e-11
gi|11385674|gb|AAG34918.1|AF281137_1 MurM [Streptococcus pneumon... 73 1e-11
gi|11385680|gb|AAG34921.1|AF281140_1 MurM [Streptococcus pneumon... 72 1e-11
gi|11385678|gb|AAG34920.1|AF281139_1 MurM [Streptococcus pneumon... 72 2e-11
gi|22536688|ref|NP_687539.1| beta-lactam resistance factor [Stre... 69 1e-10
gi|15900523|ref|NP_345127.1| beta-lactam resistance factor [Stre... 66 9e-10
gi|15902584|ref|NP_358134.1| Serine/alanine adding enzyme [Strep... 65 2e-09
gi|12746259|gb|AAK07417.1| MurM [Streptococcus pneumoniae] 65 3e-09
gi|13324647|gb|AAK18829.1|AF327739_6 MurM [Streptococcus thermop... 64 4e-09
gi|11385670|gb|AAG34916.1|AF281135_1 MurM [Streptococcus pneumon... 64 4e-09
gi|18311072|ref|NP_563006.1| methicillin resistance factor [Clos... 64 5e-09
gi|11385676|gb|AAG34919.1|AF281138_1 MurM [Streptococcus pneumon... 62 1e-08
gi|7672301|emb|CAB89537.1| MurM protein [Streptococcus pneumonia... 62 2e-08
gi|11385672|gb|AAG34917.1|AF281136_1 MurM [Streptococcus pneumon... 59 2e-07
gi|19745722|ref|NP_606858.1| putative peptidoglycan branched pep... 57 8e-07
gi|15674694|ref|NP_268868.1| putative peptidoglycan branched pep... 55 2e-06
gi|28896332|ref|NP_802682.1| putative peptidoglycan branched pep... 54 4e-06
gi|21909971|ref|NP_664239.1| putative peptidoglycan branched pep... 54 5e-06
gi|23024458|ref|ZP_00063669.1| hypothetical protein [Leuconostoc... 53 8e-06
>gi|22536687|ref|NP_687538.1| beta-lactam resistance factor
[Streptococcus agalactiae 2603V/R]
gi|22533528|gb|AAM99410.1|AE014215_4 beta-lactam resistance factor
[Streptococcus agalactiae 2603V/R]
Length = 411
Score = 787 bits (2033), Expect = 0.0
Identities = 411/411 (100%), Positives = 411/411 (100%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI
Sbjct: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG
Sbjct: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA
Sbjct: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR
Sbjct: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK
Sbjct: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG
Sbjct: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRRT 411
IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRRT
Sbjct: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRRT 411
>gi|25010623|ref|NP_735018.1| Unknown [Streptococcus agalactiae
NEM316]
gi|23094977|emb|CAD46198.1| Unknown [Streptococcus agalactiae
NEM316]
Length = 411
Score = 787 bits (2032), Expect = 0.0
Identities = 410/411 (99%), Positives = 411/411 (99%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI
Sbjct: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG
Sbjct: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA
Sbjct: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR
Sbjct: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK
Sbjct: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEY+MQEALKRQSTFYNFLG
Sbjct: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYIMQEALKRQSTFYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRRT 411
IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRRT
Sbjct: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRRT 411
>gi|25011461|ref|NP_735856.1| unknown [Streptococcus agalactiae
NEM316]
gi|18496272|emb|CAC83745.1| Fem-homologue [Streptococcus
agalactiae]
gi|24412999|emb|CAD47078.1| unknown [Streptococcus agalactiae
NEM316]
Length = 411
Score = 583 bits (1503), Expect = e-165
Identities = 296/410 (72%), Positives = 345/410 (83%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M L+ELT +EF+ +SGNYD QSF+QTPEMAKLL+KRGYD+ Y+GYQ++ K+EIIS+ Y +
Sbjct: 1 MTLRELTIEEFKEHSGNYDSQSFLQTPEMAKLLEKRGYDVRYLGYQVENKLEIISLSYIM 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
P+TGG M+++SGP HSNSKYLK FYK LQ YAKS G LEL+++PYD YQ FT G P
Sbjct: 61 PVTGGFQMKIDSGPVHSNSKYLKQFYKALQGYAKSNGVLELIVEPYDDYQLFTSSGVPSN 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
N LI+D TS GYHHDGL G+ G WHYVKNLEG+T + LL SFSK GR LVKKA
Sbjct: 121 QGNDNLIEDFTSSGYHHDGLTTGFTGKYLSWHYVKNLEGVTSETLLSSFSKTGRALVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
MSFGIK+RVLKR+ELH+FK+IT+STS+RRDYMDKSLDYYQDFYDSF KAEFVIATLNFR
Sbjct: 181 MSFGIKVRVLKRDELHLFKEITTSTSNRRDYMDKSLDYYQDFYDSFEGKAEFVIATLNFR 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EYDHNLQ+ A+ LE ++ +LD R + N DS KYHRQR+E++NQLAS + RR+EV+ FIQK
Sbjct: 241 EYDHNLQIKAEALENKLKLLDERFRENADSPKYHRQRSEIINQLASFETRRQEVQSFIQK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+ NQDVVLAGSLF+YS KETVY FSGSYTEFNKFYAPAVLQEYVMQEALKR STFYN LG
Sbjct: 301 YDNQDVVLAGSLFVYSLKETVYFFSGSYTEFNKFYAPAVLQEYVMQEALKRGSTFYNLLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
IQG FDGSD +LRFKQNFNGYI+RKMGTF YYP+P KYK IQLLKK+L+R
Sbjct: 361 IQGTFDGSDSILRFKQNFNGYIIRKMGTFNYYPSPFKYKGIQLLKKVLKR 410
>gi|22537496|ref|NP_688347.1| beta-lactam resistance factor
[Streptococcus agalactiae 2603V/R]
gi|22534375|gb|AAN00220.1|AE014253_18 beta-lactam resistance factor
[Streptococcus agalactiae 2603V/R]
Length = 411
Score = 583 bits (1502), Expect = e-165
Identities = 295/410 (71%), Positives = 344/410 (82%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M L+ELT +EF+ +SGNYD QSF+QTPEMAKLL+KRGYD+ Y+GYQ++ K+EIIS+ Y +
Sbjct: 1 MTLRELTIEEFKEHSGNYDSQSFLQTPEMAKLLEKRGYDVRYLGYQVENKLEIISLSYIM 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
P+TGG M+++SGP HSNSKYLK FYK LQ YAKS G LEL+++PYD YQ FT G P
Sbjct: 61 PVTGGFQMKIDSGPVHSNSKYLKQFYKALQGYAKSNGVLELIVEPYDDYQLFTSSGVPSN 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
N LI+D TS GYHHDGL G+ G WHYVKNLEG+T + LL SFSK GR LVKKA
Sbjct: 121 QGNDNLIEDFTSSGYHHDGLTTGFTGKYLSWHYVKNLEGVTSETLLSSFSKTGRALVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
MSFGIK+RVLKR+ELH+FK+IT+STS+RRDYMDKSLDYYQDFYDSF KAEFVIATLNFR
Sbjct: 181 MSFGIKVRVLKRDELHLFKEITTSTSNRRDYMDKSLDYYQDFYDSFEGKAEFVIATLNFR 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EYDHNLQ+ A+ LE ++ +LD R + N DS KYHRQR+E++NQLAS + RR+EV+ FIQK
Sbjct: 241 EYDHNLQIKAEALENKLKLLDERFRENADSPKYHRQRSEIINQLASFETRRQEVQSFIQK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+ NQDVVLAGSLF+YS KETVY FSGSYTEFNKFYAPAVLQEYVMQEALKR STFYN LG
Sbjct: 301 YDNQDVVLAGSLFVYSLKETVYFFSGSYTEFNKFYAPAVLQEYVMQEALKRGSTFYNLLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
IQG FDGSD +LRFKQNFNG I+RKMGTF YYP+P KYK IQLLKK+L+R
Sbjct: 361 IQGTFDGSDSILRFKQNFNGCIIRKMGTFNYYPSPFKYKGIQLLKKVLKR 410
>gi|24379184|ref|NP_721139.1| putative peptidoglycan branched
peptide synthesis protein; alanine adding enzyme;
beta-lactam resistance factor MurN [Streptococcus mutans
UA159]
gi|24377093|gb|AAN58445.1|AE014914_7 putative peptidoglycan
branched peptide synthesis protein; alanine adding
enzyme; beta-lactam resistance factor MurN
[Streptococcus mutans UA159]
Length = 410
Score = 470 bits (1210), Expect = e-131
Identities = 243/410 (59%), Positives = 308/410 (74%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MAL+ ++ +F + + +SFMQT EMAKLL KRG+ + Y+ + +G +EI +I+Y++
Sbjct: 1 MALQNISQNDFALHVQKAEQKSFMQTLEMAKLLSKRGFTLNYIAWLENGTIEISAILYSM 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
PMTGG + E+N GP + K+L FY+EL++Y K +GALEL+IKPYDTYQ F G+G+
Sbjct: 61 PMTGGRYFEINCGPVVTRDKHLTDFYRELKDYVKEKGALELVIKPYDTYQTFDGDGQATS 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
A LI LT++GYH DGL YP GEPDWHYVK+L I+ Q LLKSFSKKGRPLVKKA
Sbjct: 121 AEKKELISQLTNLGYHFDGLQRDYPNGEPDWHYVKDLSDISEQTLLKSFSKKGRPLVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FG K+R L R+EL++FK+ITS+TSDRR+Y DKSLDYYQDFYDSFG+ AEF+IA+LNF
Sbjct: 181 KTFGTKLRRLNRDELNLFKEITSATSDRREYSDKSLDYYQDFYDSFGNNAEFMIASLNFE 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
Y +LQ + KL +I L + N S K Q EL +Q + R++E + FI K
Sbjct: 241 NYLSHLQRDQNKLGNKIAKLQADLEKNPHSEKKQNQLRELSSQFDTFTTRQEEAQKFITK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +DV+LAGSLF+Y+P+E VYLFSGSY EFNKFYAPA+LQE+VM EALKR +FYN LG
Sbjct: 301 YGKKDVILAGSLFVYTPQEAVYLFSGSYPEFNKFYAPALLQEHVMLEALKRGISFYNLLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
I G+FD SDGVLRFKQNFNGYIVRKMGTF YYPNPLKY+ + +KKILRR
Sbjct: 361 ITGHFDNSDGVLRFKQNFNGYIVRKMGTFHYYPNPLKYRLLNTIKKILRR 410
>gi|12746258|gb|AAK07416.1| MurN [Streptococcus pneumoniae]
Length = 410
Score = 457 bits (1175), Expect = e-127
Identities = 241/410 (58%), Positives = 302/410 (72%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MAL LT +EF +YS +SFMQ+ +M LL KRG I Y+ + +G++++ ++VY++
Sbjct: 1 MALTTLTKEEFRTYSDQVSSRSFMQSVQMGDLLDKRGARIVYLALKQEGEIQVAALVYSL 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
PM GGLHME+NSGP ++ L FY EL+ YAK G LELL+KPY+TYQ F EG P
Sbjct: 61 PMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSEGNPID 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
A +I LT +GY DGL +GYPGGEPDW Y K+L +T +NLLKSFSKKG+PLVKKA
Sbjct: 121 AEKKSIIQGLTDLGYQFDGLTMGYPGGEPDWLYYKDLTELTEKNLLKSFSKKGKPLVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGI+++ LKREEL IFK+IT TS+RR+Y DKSL+YY+ FYDSFG++AEF+IA+LNF
Sbjct: 181 ETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDSFGEQAEFLIASLNFS 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EY LQ KLEE + L N S K Q E +Q + + R+ E I+K
Sbjct: 241 EYMSKLQGEQSKLEEILDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +D+VLAGSLF+Y P+ET YLFSGSYTEFNKFYAPA+LQ+YVM E++KR YNFLG
Sbjct: 301 YGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
IQG FDGSDGVLRFKQNFNGYIVRK GTFRY+P+PLKYK+IQLLKKI+ R
Sbjct: 361 IQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLKKIVGR 410
>gi|15900524|ref|NP_345128.1| beta-lactam resistance factor
[Streptococcus pneumoniae TIGR4]
gi|25388505|pir||G95071 beta-lactam resistance factor [imported] -
Streptococcus pneumoniae (strain TIGR4)
gi|7649683|emb|CAB89121.1| beta-lactam resistance factor
[Streptococcus pneumoniae]
gi|14972092|gb|AAK74768.1| beta-lactam resistance factor
[Streptococcus pneumoniae TIGR4]
Length = 410
Score = 455 bits (1170), Expect = e-127
Identities = 238/410 (58%), Positives = 304/410 (74%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MAL LT +EF++YS +SFMQ+ +M LL+KRG I Y+ + +G++++ ++VY++
Sbjct: 1 MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSL 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
PM GGLHME+NSGP ++ L FY EL+ YAK G LELL+KPY+TYQ F +G P
Sbjct: 61 PMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPID 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
A +I DLT +GY DGL GYPGGEPDW Y K+L +T ++LLKSFSKKG+PLVKKA
Sbjct: 121 AEKKSIIQDLTDLGYQFDGLTTGYPGGEPDWLYYKDLTELTEKSLLKSFSKKGKPLVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGI+++ LKREEL IFK+IT TS+RR+Y DKSL+YY+ FYD+FG++AEF+IA+LNF
Sbjct: 181 ETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQAEFLIASLNFS 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
+Y LQ KLEE + L N S K Q E +Q + + R+ E I+K
Sbjct: 241 DYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +D+VLAGSLF+Y P+ET YLFSGSYTEFNKFYAPA+LQ+YVM E++KR YNFLG
Sbjct: 301 YGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
IQG FDGSDGVLRFKQNFNGYIVRK GTFRY+P+PLKYK+IQLLKKI+ R
Sbjct: 361 IQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLKKIVGR 410
>gi|15902585|ref|NP_358135.1| Alanine adding enzyme [Streptococcus
pneumoniae R6]
gi|25508351|pir||E97939 alanine adding enzyme [imported] -
Streptococcus pneumoniae (strain R6)
gi|7672299|emb|CAB89536.1| MurN protein [Streptococcus pneumoniae]
gi|15458116|gb|AAK99345.1| Alanine adding enzyme [Streptococcus
pneumoniae R6]
gi|16605464|emb|CAC80803.1| MurN protein [Streptococcus pneumoniae]
Length = 410
Score = 452 bits (1163), Expect = e-126
Identities = 237/410 (57%), Positives = 303/410 (73%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MAL LT +EF++YS +SFMQ+ +M LL+KRG I Y+ + +G++++ ++VY++
Sbjct: 1 MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSL 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
PM GGLHME+NSGP ++ L FY EL+ YAK G LELL+KPY+TYQ F +G P
Sbjct: 61 PMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPID 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
A +I LT +GY DGL GYPGGEPDW Y K+L +T ++LLKSFSKKG+PLVKKA
Sbjct: 121 AEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTELTEKSLLKSFSKKGKPLVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGI+++ LKREEL IFK+IT TS+RR+Y DKSL+YY+ FYD+FG++AEF+IA+LNF
Sbjct: 181 ETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQAEFLIASLNFS 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
+Y LQ KLEE + L N S K Q E +Q + + R+ E I+K
Sbjct: 241 DYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +D+VLAGSLF+Y P+ET YLFSGSYTEFNKFYAPA+LQ+YVM E++KR YNFLG
Sbjct: 301 YGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
IQG FDGSDGVLRFKQNFNGYIVRK GTFRY+P+PLKYK+IQLLKKI+ R
Sbjct: 361 IQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLKKIVGR 410
>gi|7672302|emb|CAB89538.1| MurN protein [Streptococcus pneumoniae]
Length = 410
Score = 452 bits (1162), Expect = e-126
Identities = 236/410 (57%), Positives = 302/410 (73%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M L LT +EF++YS +SFMQ+ +M LL+KRG I Y+ + +G++++ ++VY++
Sbjct: 1 MVLTTLTKEEFQAYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSL 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
PM GGLHME+NSGP ++ L FY EL+ YAK G LELL+KPY+TYQ F +G P
Sbjct: 61 PMLGGLHMEINSGPIYTQQDALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPID 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
A +I LT +GY DGL GYPGGEPDW Y K+L +T ++LLKSFSKKG+PLVKKA
Sbjct: 121 AEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTELTEKSLLKSFSKKGKPLVKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGI+++ LKREEL IFK+IT TS+RR+Y DKSL+YY+ FYD+FG++AEF+IA+LNF
Sbjct: 181 ETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDTFGEQAEFLIASLNFS 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
+Y LQ KLEE + L N S K Q E +Q + + R+ E I+K
Sbjct: 241 DYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +D+VLAGSLF+Y P+ET YLFSGSYTEFNKFYAPA+LQ+YVM E++KR YNFLG
Sbjct: 301 YGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
IQG FDGSDGVLRFKQNFNGYIVRK GTFRY+P+PLKYK+IQLLKKI+ R
Sbjct: 361 IQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLKKIVGR 410
>gi|7672305|emb|CAB89540.1| MurN protein [Streptococcus pneumoniae]
Length = 410
Score = 450 bits (1158), Expect = e-125
Identities = 237/410 (57%), Positives = 301/410 (72%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M L LT +EF++YS +SFMQ+ +M LL+KRG I Y+ + +G++++ ++VY++
Sbjct: 1 MVLTTLTKEEFQAYSDQVSSRSFMQSVQMGDLLEKRGARIVYLALKQEGEIQVAALVYSL 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
PM GGLHME+NSGP ++ L FY EL+ YAK G LELL+KPY+TYQ F +G P
Sbjct: 61 PMLGGLHMEINSGPIYTQQDALPVFYAELKEYAKQNGVLELLVKPYETYQTFDSQGNPID 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
A +I LT +GY DGL GYPGGEPDW Y K+L +T +NLLKSFSKKG+PLVKK+
Sbjct: 121 AEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTELTEKNLLKSFSKKGKPLVKKS 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGI+++ LKREEL IFK+IT TS+RR+Y DKSL+YY+ FYDSFG++AEF+IA+LNF
Sbjct: 181 ETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEYYEHFYDSFGEQAEFLIASLNFS 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EY LQ KLEE + L N S K Q E +Q + + R+ E I+K
Sbjct: 241 EYMSKLQGEQSKLEEILDKLRLDLSKNPHSEKKQNQLREYSSQFETFEVRKAEARDLIEK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +D+VLAGSLF+Y +ET YLFSGSYTEFNKFYAPA+LQ+YVM E++KR YNFLG
Sbjct: 301 YGEEDIVLAGSLFVYMSQETTYLFSGSYTEFNKFYAPALLQKYVMLESIKRGIPKYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
IQG FDGSDGVLRFKQNFNGYIVRK GTFRY+P+PLKYK+IQLLKKI+ R
Sbjct: 361 IQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYHPSPLKYKAIQLLKKIVGR 410
>gi|19745721|ref|NP_606857.1| putative peptidoglycan branched
peptide synthesis protein alanine adding enzyme
[Streptococcus pyogenes MGAS8232]
gi|19747858|gb|AAL97356.1| putative peptidoglycan branched peptide
synthesis protein alanine adding enzyme [Streptococcus
pyogenes MGAS8232]
Length = 411
Score = 420 bits (1080), Expect = e-116
Identities = 217/410 (52%), Positives = 291/410 (70%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MAL E++ ++F+ Y + SF+QT EMA L+ KRG ++G + DG++++ ++V++
Sbjct: 1 MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLGLEKDGELKVAAMVFSQ 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
+ GG ME+N+GP ++ + L+HFY +L++YAK + +EL++KPYD YQ F +G P
Sbjct: 61 KVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELILKPYDNYQSFDTDGIPIS 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
PNT LI LT++GY HDGL GYP GEP WHYVK LEGI L SFSKKG+ L+KKA
Sbjct: 121 HPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGIDSSRLTHSFSKKGKALIKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGIK+R LKR+ELH FK+IT +TSDRRDY+DKSL YYQDFYDSFGD EF++ATLNF
Sbjct: 181 NTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYDSFGDSCEFIVATLNFE 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
+Y +NL+ +L I + N S K + EL +Q + R E F+++
Sbjct: 241 DYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQFETFQVRISEALHFLEE 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +DV LAGSLFIY+ +E VYLFSGSY +FNKFY+PA+LQE+ M +A+ + YNFLG
Sbjct: 301 YGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHAMLKAIHKGIKQYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
I GNFDGSDGVLRFKQNFNG+I++K GTFR YP P+KY I+L KK+L R
Sbjct: 361 ITGNFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFIRLAKKLLNR 410
>gi|15674693|ref|NP_268867.1| putative peptidoglycan branched
peptide synthesis protein, alanine adding enzyme
[Streptococcus pyogenes]
gi|13621812|gb|AAK33588.1| putative peptidoglycan branched peptide
synthesis protein, alanine adding enzyme [Streptococcus
pyogenes M1 GAS]
Length = 411
Score = 418 bits (1075), Expect = e-116
Identities = 216/410 (52%), Positives = 291/410 (70%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MAL E++ ++F+ Y + SF+QT EMA L+ KRG ++G + DG++++ ++V++
Sbjct: 1 MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLGLEKDGELKVAAMVFSQ 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
+ GG ME+N+GP ++ + L+HFY +L++YAK + +EL++KPYD YQ F +G P
Sbjct: 61 KVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELILKPYDNYQSFDTDGIPIS 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
PNT LI LT++GY HDGL GYP GEP WHYVK LEGI L +SFSKKG+ L+KKA
Sbjct: 121 RPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGIDSSRLTRSFSKKGKALIKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGIK+R LKR+ELH FK+IT +TSDRRDY+DKSL YYQDFYDSFGD EF++ATLNF
Sbjct: 181 NTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYDSFGDSCEFMVATLNFE 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
+Y +NL+ +L I + N S K + EL +Q + R E F+++
Sbjct: 241 DYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQFETFQVRISEALHFLEE 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +DV LAGSLFIY+ +E VYLFSGSY +FNKFY+PA+LQE+ M +A+ + YNFLG
Sbjct: 301 YGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKFYSPALLQEHAMLKAIHKGIKQYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
I G FDGSDGVLRFKQNFNG+I++K GTFR YP P+KY I+L KK+L R
Sbjct: 361 ITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFIRLAKKLLNR 410
>gi|21909970|ref|NP_664238.1| putative peptidoglycan branched
peptide synthesis protein, alanine adding enzyme
[Streptococcus pyogenes MGAS315]
gi|28896333|ref|NP_802683.1| putative peptidoglycan branched
peptide synthesis protein, alanine adding enzyme
[Streptococcus pyogenes SSI-1]
gi|21904159|gb|AAM79041.1| putative peptidoglycan branched peptide
synthesis protein, alanine adding enzyme [Streptococcus
pyogenes MGAS315]
gi|28811584|dbj|BAC64516.1| putative peptidoglycan branched peptide
synthesis protein, alanine adding enzyme [Streptococcus
pyogenes SSI-1]
Length = 411
Score = 417 bits (1072), Expect = e-115
Identities = 216/410 (52%), Positives = 290/410 (70%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
MAL E++ ++F+ Y + SF+QT EMA L+ KRG ++G + DG++++ ++V++
Sbjct: 1 MALIEISQEQFDHYCHSLVRHSFIQTSEMASLMAKRGAKPQFLGLEKDGELKVAAMVFSQ 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
+ GG ME+N+GP ++ + L+HFY +L++YAK + +EL++KPYD YQ F +G P
Sbjct: 61 KVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELILKPYDNYQSFDTDGIPIS 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
PNT LI LT++GY HDGL GYP GEP WHYVK LEGI L SFSKKG+ L+KKA
Sbjct: 121 HPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGIDSSRLTHSFSKKGKALIKKA 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGIK+R LKR+ELH FK+IT +TSDRRDY+DKSL YYQDFYDSFGD EF++ATLNF
Sbjct: 181 NTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSYYQDFYDSFGDSCEFMVATLNFE 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
+Y +NL+ +L I + N S K + EL +Q + R E F+++
Sbjct: 241 DYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNRLKELSSQFETFQVRISEALHFLEE 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G +DV LAGSLFIY+ +E VYLFSGSY +FNKFY+PA+LQE+ M +A+ + YNFLG
Sbjct: 301 YGTKDVFLAGSLFIYTKQEAVYLFSGSYPKFNKFYSPALLQEHAMLKAIHKGIKQYNFLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
I G FDGSDGVLRFKQNFNG+I++K GTFR YP P+KY I+L KK+L R
Sbjct: 361 ITGKFDGSDGVLRFKQNFNGFILQKPGTFRCYPFPIKYHFIRLAKKLLNR 410
>gi|2804352|gb|AAC46073.1| zoocin A immunity factor [Streptococcus
equi subsp. zooepidemicus]
Length = 410
Score = 361 bits (926), Expect = 2e-98
Identities = 203/410 (49%), Positives = 267/410 (64%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M +E+ A FE ++ +SF QT EM L K R +D+ Y +++++++ YT
Sbjct: 1 MKFQEIDALTFEKFANTQKRRSFEQTIEMGNLRKSRNFDVKYFALFHLEEIKVVALTYTQ 60
Query: 61 PMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKG 120
+ GGL+M + GP S +YL HF EL+ Y K LEL I PYD YQ + EG+
Sbjct: 61 KIFGGLNMGIYYGPIFSEERYLAHFLIELKKYTKKNNVLELDIFPYDDYQYYDDEGRLIQ 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
N L D G+ + G +G+ + WHYVK+L +T +NLL SFSKKGRPLVKK+
Sbjct: 121 DGNIELRDIFEKAGFTYQGDEVGFNSEQVTWHYVKDLTNLTSENLLNSFSKKGRPLVKKS 180
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+FGIK+R L ++EL IF +IT+ T+ RR Y DK L+YY+ F+D+F DK+EF IATLNFR
Sbjct: 181 NTFGIKVRKLNKDELQIFANITNDTATRRGYNDKGLEYYEKFFDAFKDKSEFTIATLNFR 240
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EY N+ +LE +I++L R N +S K Q EL +Q + R +E + F++K
Sbjct: 241 EYLGNILDGRHRLENKISILGTRLDKNPNSEKIKNQLRELNSQRETFLIREEEAKSFVKK 300
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
+G++DVVLAGSLF+Y+ +E VYL+SGSY EFNKFYAPA+LQEY M ALK+ FYN LG
Sbjct: 301 YGDEDVVLAGSLFVYTQQELVYLYSGSYVEFNKFYAPALLQEYAMLNALKKGIKFYNMLG 360
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
I G FD SDGVL FKQNF GYIVRK F YYPNP K K IQL+K ILRR
Sbjct: 361 ITGKFDNSDGVLCFKQNFKGYIVRKFSNFIYYPNPRKLKVIQLIKSILRR 410
>gi|29376659|ref|NP_815813.1| FemAB family protein [Enterococcus
faecalis V583]
gi|29344123|gb|AAO81883.1| FemAB family protein [Enterococcus
faecalis V583]
Length = 426
Score = 245 bits (625), Expect = 1e-63
Identities = 143/412 (34%), Positives = 235/412 (56%), Gaps = 20/412 (4%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKM--------EIISIV 57
LT +EF +++ + +F++TPEM LL++RG+ Y+G + +G++ + + I
Sbjct: 21 LTEQEFTTFAMTHPAGNFLETPEMKHLLERRGWHCEYVGVKREGQLIAACILSKKKVKIG 80
Query: 58 YTIPMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDT--YQEFTGE 115
Y + GG+ M+ +++ K ++ F+ L+ Y K L L P ++F G
Sbjct: 81 YAFDIDGGILMD------YTDKKCVEAFFTGLKKYVKKNDGLYLTFTPNKQICLRDFNGG 134
Query: 116 GKPKGAPNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLKSFSKKGRP 175
K T+ D TSIG+ H G + G P W +VK++ G+T ++L KS+ K +
Sbjct: 135 EVEKVNQETF--DYFTSIGFEHQGFDVHNFDGAPRWLFVKDMAGLTEEDLWKSYGKDAKY 192
Query: 176 LVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIA 235
+KK +G+ IR L+ EEL +FK +T TS RR++ DK L YYQ Y+ FG++A+F++A
Sbjct: 193 DIKKTWEYGVTIRELRYEELPLFKKLTEETSARRNFEDKDLAYYQAVYEEFGERAKFMVA 252
Query: 236 TLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVE 295
LNF Y NL +KL+E + ++ N S K + Q+ E +++ ++ KR E +
Sbjct: 253 ELNFATYLENLHEKLRKLQETLNEVNEALIANPKSRKKNNQKREFEDEVRTVRKRIDEAK 312
Query: 296 PFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTF 355
K ++ +LAG+LFI P+E VYLFSG+Y ++ ++YAP ++Q ++ ++
Sbjct: 313 EM--KTSDEPEILAGALFIVHPQEVVYLFSGTYEKYKQYYAPYLIQHKMLTYTVENNIPK 370
Query: 356 YNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF G+ G FDGSDGVL+FKQ+F G++ MG F++ P+KY LK I
Sbjct: 371 YNFYGVDGIFDGSDGVLKFKQSFGGHVEELMGNFQWKAKPMKYALYHALKTI 422
>gi|23038199|ref|ZP_00070374.1| hypothetical protein [Oenococcus
oeni MCW]
Length = 422
Score = 230 bits (587), Expect = 3e-59
Identities = 138/415 (33%), Positives = 236/415 (56%), Gaps = 9/415 (2%)
Query: 5 ELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQID-GKMEIISIVYTIPMT 63
EL+ E+ ++ N+ +F+Q+ E LL+KRG + +G + D GK+ ++V +
Sbjct: 7 ELSVLEYANFENNHPQGNFVQSAEQKSLLEKRGENAALVGLKDDTGKVVAGALVTWAKVK 66
Query: 64 GGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGA 121
G + GP +SN + +K F L ++K + L + I+P Y ++T GK G
Sbjct: 67 LGNLFSIERGPLLDYSNEQLIKAFISGLTVFSKKRDGLFIRIRPNIAYAKYTERGKLIGD 126
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYP-GGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
NT ++ L S+ H IG+ EP+W +VK+L + P++++KS++++ + + K
Sbjct: 127 KNTTFVEKLNSLAADHQLPQIGFSTSSEPEWQFVKDLTEVDPEHVVKSYNRQAKYHLNKN 186
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
F IK+R + R+EL FK IT T+DR Y DKSLD+Y+ +D++G KA+F+ A +NF+
Sbjct: 187 KQFCIKLRKIGRDELPAFKRITQQTADRLHYHDKSLDFYETLFDTYGKKAKFIFAEINFK 246
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTD-----SAKYHRQRTELVNQLASLDKRRKEVE 295
EY +++ + +++++T + +N SA R +E + +L KR +E +
Sbjct: 247 EYSESIEKDLNDIQKKLTEIAGADYHNISDLSDFSASAKRHLSEGIKTETALQKRLQEAK 306
Query: 296 PFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTF 355
Q+ + V+++ +LF+ +E VYL+SGS ++ +AP +Q+ ++ EA+K +
Sbjct: 307 KMHQEAKHDIVLVSVALFVIENQEVVYLYSGSDEKYEHLFAPYEIQDTMITEAVKERIPL 366
Query: 356 YNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF G+ G FDGSDGVL FK +FNGY +G+F + KY +L KKIL R
Sbjct: 367 YNFYGVSGKFDGSDGVLGFKTHFNGYTREMVGSFDFPVQKTKYYFYRLFKKILHR 421
>gi|23024426|ref|ZP_00063638.1| hypothetical protein [Leuconostoc
mesenteroides subsp. mesenteroides ATCC 8293]
Length = 417
Score = 223 bits (567), Expect = 6e-57
Identities = 137/410 (33%), Positives = 222/410 (53%), Gaps = 4/410 (0%)
Query: 5 ELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTG 64
ELT +E+ + + +F+Q+ E A+LL+KRGY I +G + D K+ ++V +
Sbjct: 7 ELTKEEYTEFEKQSSVGTFLQSGEQAELLQKRGYKIWLLGIKADDKVVAAALVMREKVHM 66
Query: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGAP 122
G ++ GP N + L F +++ L + ++P T + G G
Sbjct: 67 GYIFSIDRGPLLDFENHELLAFFMSNFVKFSRENKGLYIEVRPNVTLKMTNNHGDLLGEE 126
Query: 123 NTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLK-SFSKKGRPLVKKA 180
NT I+++ +G+ H G+ G P+W Y+K+L +T + ++ S++KK + +KK
Sbjct: 127 NTVFIEEMKKLGFTHLPFVDGFTTAGSPEWEYIKDLSELTDEKSVRASYNKKAQYYLKKN 186
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
FGI++R L R++L FK++T T+DR Y DK+L++YQ YD +GD A FV A LNF
Sbjct: 187 AQFGIRLRQLTRDDLPDFKELTQKTADRLHYKDKNLNFYQTVYDVYGDDATFVFAELNFD 246
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
Y +L+ ++ ++ + + + K+ RQ E +Q KR + E +
Sbjct: 247 NYIKEENEKISELDAKLAKINQKIEKYPTNDKFKRQYAEFDDQKNQHSKRILKAEQQKEA 306
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
G VV+AG+LFI P+E YL+SG+Y E+ +Y P +Q+ ++ +A++ YNF G
Sbjct: 307 AGKSTVVVAGALFIQQPQEMNYLYSGTYEEYMDYYGPYQIQDVMINKAVQAGLKRYNFYG 366
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
I G FDGSDGVL FK F G + +G F NP KY +LLKK++ R
Sbjct: 367 IAGKFDGSDGVLGFKTTFEGQARQLVGNFMMPVNPFKYGVYRLLKKMMGR 416
>gi|23335849|ref|ZP_00121081.1| hypothetical protein
[Bifidobacterium longum DJO10A]
Length = 499
Score = 211 bits (536), Expect = 2e-53
Identities = 140/426 (32%), Positives = 223/426 (51%), Gaps = 27/426 (6%)
Query: 3 LKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPM 62
L +LT +EF+ +S + +F QT M +L +G D+ Y+ + K+ ++ T
Sbjct: 83 LVKLTDEEFDDFSARHPQGNFQQTSAMGRLRAAQGIDVEYLALKEGEKIVAAALFETHRS 142
Query: 63 TGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY--QEFTGEGKP 118
++ GP + +++ L F L+ +AK++GA +L I P Y ++ G P
Sbjct: 143 RFSTFAVIHDGPMCDYHDTEALTFFMDALKRHAKAKGASQLEITPESPYRLRDTNGASLP 202
Query: 119 ---KGAPNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQ-NLLKSFSKKGR 174
GAP+ LI+ L +IG+ H G +GY P W Y+K+L GIT + +LLKS+ K+ +
Sbjct: 203 DDQNGAPDNKLIEQLEAIGFTHGGFTVGYT-AVPRWRYLKDLTGITDEKSLLKSYDKRTQ 261
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
VK+A S G+ +R L +EL +F I T++RR + + Y+ F ++FG KA F++
Sbjct: 262 WSVKRAQSMGVHVRELSDDELGVFARIEQQTAERRSFEYRGEAYFHRFKEAFGSKAHFMV 321
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A ++ EY ++ + L ++ L ++ + + K RQ E LA+++KR E
Sbjct: 322 AEIHIDEYVADMTSKREALSAKVAALTAKNAEHP-TTKTERQLGEETRNLAAVEKRLNEA 380
Query: 295 EPFIQKFGNQDVV-LAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQ-----EYVMQEA 348
F + + DV+ A SLF+ P+E +YLFSGS ++ FYA A++Q + ++
Sbjct: 381 AEFAK---DGDVLPAAASLFVEHPREVIYLFSGSVEQYKPFYASALIQHDAMLHFCVEHG 437
Query: 349 LKRQSTFYNFLGIQGNFDGSD----GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLL 404
L R YNF GI G FD D GVL FKQ FNGY+ G F P+ Y Q
Sbjct: 438 LSR----YNFYGIDGVFDDPDDEGRGVLEFKQGFNGYVEELPGEFVLPVKPVAYAMKQFA 493
Query: 405 KKILRR 410
K+L R
Sbjct: 494 HKLLSR 499
>gi|23464885|ref|NP_695488.1| FemAB-like protein possibly involved
in interpeptide bridge formation in peptidoglycan
[Bifidobacterium longum NCC2705]
gi|23325475|gb|AAN24124.1|AE014647_3 FemAB-like protein possibly
involved in interpeptide bridge formation in
peptidoglycan [Bifidobacterium longum NCC2705]
Length = 422
Score = 206 bits (524), Expect = 6e-52
Identities = 140/426 (32%), Positives = 223/426 (51%), Gaps = 27/426 (6%)
Query: 3 LKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPM 62
L +LT +EF+ +S + +F QT M +L +G D+ Y+ + K+ ++ T
Sbjct: 6 LVKLTDEEFDDFSARHPQGNFQQTSAMGRLRAAQGIDVEYLALKEGEKIVAAALFETHRS 65
Query: 63 TGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY--QEFTGEGKP 118
++ GP + +++ L F L+ +AK++GA +L I P +Y ++ G P
Sbjct: 66 RFSTFAVIHDGPMCDYHDTEALTFFMDALKRHAKAKGASQLEITPESSYRLRDTNGASLP 125
Query: 119 ---KGAPNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQ-NLLKSFSKKGR 174
GAP+ LI+ L +IG+ H G +GY P W Y+K+L GIT + +LLKS+ K+ +
Sbjct: 126 DDQNGAPDNKLIEQLEAIGFTHGGFTVGYT-AVPRWRYLKDLTGITDEKSLLKSYDKRTQ 184
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
VK+A S G+ +R L +EL +F I T++RR + + Y+ F ++FG KA F++
Sbjct: 185 WSVKRAQSMGVHVRELSDDELGVFARIEQQTAERRSFEYRGEAYFHRFKEAFGSKAHFMV 244
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A ++ EY ++ + L ++ L ++ + + K RQ E LA+ +KR E
Sbjct: 245 AEIHIDEYVADMTSKREALSAKVAALTAKNAEHP-TTKTERQLGEETRNLAAAEKRLNEA 303
Query: 295 EPFIQKFGNQDVV-LAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQ-----EYVMQEA 348
F + + DV+ A SLF+ P+E +YLFSGS ++ FYA A++Q + ++
Sbjct: 304 AEFAK---DGDVLPAAASLFVEHPREVIYLFSGSVEQYKPFYASALIQHDAMLHFCVEHG 360
Query: 349 LKRQSTFYNFLGIQGNFDGSD----GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLL 404
L R YNF GI G FD D GVL FKQ FNGY+ G F P+ Y Q
Sbjct: 361 LSR----YNFYGIDGVFDDPDDEGRGVLEFKQGFNGYVEELPGEFVLPVKPVAYAMKQFA 416
Query: 405 KKILRR 410
K+L R
Sbjct: 417 HKLLSR 422
>gi|23464883|ref|NP_695486.1| FemAB-like protein possibly involved
in interpeptide bridge formation in peptidoglycan
[Bifidobacterium longum NCC2705]
gi|23325473|gb|AAN24122.1|AE014647_1 FemAB-like protein possibly
involved in interpeptide bridge formation in
peptidoglycan [Bifidobacterium longum NCC2705]
Length = 426
Score = 193 bits (490), Expect = 5e-48
Identities = 129/416 (31%), Positives = 212/416 (50%), Gaps = 17/416 (4%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTG- 64
+T +EF+ S SF Q +L K RG++ +G D +++ + + G
Sbjct: 17 ITPEEFDRLSEATSQGSFQQWSGQVRLAKIRGHEAECVGV-CDASGNLVAGCVILYLNGR 75
Query: 65 -GLHMEVNSGP--AHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGA 121
G V GP + L+ + ++ A+ A+ + P Y+ ++ +G+P G
Sbjct: 76 FGADGSVYFGPIGISDDPALLRAITEAIRESARRHHAVSVACWPNVAYRLYSSDGQPDGE 135
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITP-QNLLKSFSKKGRPLVKKA 180
PN L+ T G+ H G H GY W YVK+L GIT + LL SF K+ + VK+A
Sbjct: 136 PNDALLTGFTDAGWTHGGFHTGY-DVVCQWMYVKDLTGITNGKELLASFGKRAQWSVKRA 194
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
S G+ +R + +E +F DI T +RR + + DY++ F ++G A F++A ++
Sbjct: 195 QSMGVHVREIGPDEFDVFADIERRTGERRGFATRGADYFRQFKQAYGADAHFMLAEIHIA 254
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EY ++ + L+ ++ L ++ + + + RQ E LA+ DKR EVE + +K
Sbjct: 255 EYVADMTAKREALQTKVAQLQTKY-DERPTTRIERQLGEESRNLAAADKRLAEVEGYAKK 313
Query: 301 FGNQDVV-LAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQ-EYVMQEALKRQSTFYNF 358
DV+ A S+F+ P E VY +SGS E+ FYA A++Q E ++ +++ + YNF
Sbjct: 314 ---GDVLPAAASMFVSHPNEVVYQYSGSLEEYKPFYASALIQYEAMLHLCVEQGVSRYNF 370
Query: 359 LGIQGNFDGSD----GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
GI G FD + GVL FKQ FNGY+ + +G F + ++ L K+LRR
Sbjct: 371 YGISGVFDDPNNEGRGVLEFKQGFNGYVEQMVGKFTLPVDKFRFGVSNLAHKLLRR 426
>gi|23335851|ref|ZP_00121083.1| hypothetical protein
[Bifidobacterium longum DJO10A]
Length = 426
Score = 190 bits (483), Expect = 4e-47
Identities = 128/416 (30%), Positives = 209/416 (49%), Gaps = 17/416 (4%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTG- 64
+T +E + S SF Q +L K RG++ +G D +++ + + G
Sbjct: 17 ITPEELDRLSEATSQGSFQQWSGQVRLAKIRGHEAECVGV-CDASGNLVTGCVILYLNGR 75
Query: 65 -GLHMEVNSGP--AHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGA 121
G V GP + L+ + ++ A+ A+ + P Y+ ++ +G+P G
Sbjct: 76 FGADGSVYFGPIGISDDPALLRAITEAIRESARRHHAVSVACWPNVAYRLYSSDGQPDGE 135
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITP-QNLLKSFSKKGRPLVKKA 180
PN L+ G+ H G H GY W YVK+L GIT + LL SF K+ + VK+A
Sbjct: 136 PNDALLAGFADAGWMHGGFHTGY-DVVCQWMYVKDLTGITNGKELLASFGKRAQWSVKRA 194
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
S G+ +R + +E +F DI T +RR + + DY++ F ++G A F++A ++
Sbjct: 195 QSMGVHVREIGPDEFDVFADIERRTGERRGFATRGADYFRQFKQAYGADAHFMLAEIHIA 254
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
EY ++ + L+ ++ L ++ + + + RQ E LA+ DKR EVE + +K
Sbjct: 255 EYVADMTAKREALQAKVARLQAKY-DERPTTRIERQLGEESRNLAAADKRLAEVEGYARK 313
Query: 301 FGNQDVV-LAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQ-EYVMQEALKRQSTFYNF 358
DV+ A S+F+ P E VY +SGS E+ FYA A++Q E ++ +++ YNF
Sbjct: 314 ---GDVLPAAASMFVSHPNEVVYQYSGSLEEYKPFYASALIQYEAMLHLCVEKGVPRYNF 370
Query: 359 LGIQGNFDGSD----GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
GI G FD D GVL FKQ FNGY+ + +G F + ++ L K+LRR
Sbjct: 371 YGISGVFDDPDDEGRGVLEFKQGFNGYVEQMVGKFTLPVDKFRFGVSNLAHKLLRR 426
>gi|23037890|ref|ZP_00070086.1| hypothetical protein [Oenococcus
oeni MCW]
Length = 359
Score = 177 bits (449), Expect = 3e-43
Identities = 124/362 (34%), Positives = 194/362 (53%), Gaps = 25/362 (6%)
Query: 63 TGGLHMEVNSGPA-----HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGK 117
TG ++ E+ GP +N++ + F KEL Y K Q A L I P + Q GK
Sbjct: 8 TGDVY-EIMGGPLVDFENENNNQIIAFFLKELHKYLKKQHAYYLRIVPNEKTQRVENNGK 66
Query: 118 PKGAPNTYLIDDLTSIGYHHDGL------HIGYPGGEPDWHYVKNLEGITPQNLLKSFSK 171
Y + + +S+ Y +G +GY P + Y K +EG+ + L +S+SK
Sbjct: 67 VV----NYDLKNYSSL-YFAEGFIYRSFEQVGYGFATPHYEYQKRIEGLNKKTLFQSYSK 121
Query: 172 KGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAE 231
K + +KK FGI R + +EL +F + T+ T+ R + DK L YYQ Y +FGD A+
Sbjct: 122 KTQYSIKKTYEFGITTRNISYDELEMFHENTTKTAKRLGFYDKELSYYQSVYRTFGDNAK 181
Query: 232 FVIATLNFREYDHNLQ---LNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLD 288
F+IA +N +Y + Q N K +Q+ ++D++ + T + RQ EL +Q+ +
Sbjct: 182 FMIAEINLSDYIGHFQEIIRNLKDKIDQMILIDSKREKPTKT----RQIKELRSQVEQHE 237
Query: 289 KRRKEVEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEA 348
KR + + I+++G + + LAG+LF P+E Y+FS + EF FY P Q +++ A
Sbjct: 238 KRIVQAKKLIEQYGKK-INLAGALFFIQPQEVSYMFSYTNAEFKNFYGPYRTQADMLEFA 296
Query: 349 LKRQSTFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKIL 408
LK + YNF G+ G+ G DGV FK+ F GY+V MG F N +Y+ +Q +KKI+
Sbjct: 297 LKEKVPVYNFYGVSGDRSGHDGVYEFKKGFQGYMVDNMGAFILPINKFRYQFLQTIKKII 356
Query: 409 RR 410
RR
Sbjct: 357 RR 358
>gi|23335850|ref|ZP_00121082.1| hypothetical protein
[Bifidobacterium longum DJO10A]
Length = 436
Score = 161 bits (407), Expect = 2e-38
Identities = 122/424 (28%), Positives = 200/424 (46%), Gaps = 20/424 (4%)
Query: 5 ELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTG 64
++T E +++S SF QT +MA + G + Y+G + K+ V
Sbjct: 15 KITPAELDAFSAAQVQGSFQQTSQMAAMGAFNG-PVDYVGVKRGDKLIAACYVVYTRSRF 73
Query: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGAP 122
GL V GP + N + ++ + L+ AK+ A+ + P Y+ +GKP P
Sbjct: 74 GLEGSVWCGPLCDYDNPQVVEAMTEALRRSAKAHHAISVSCWPAAVYRLHDLDGKPTSDP 133
Query: 123 NTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGI-TPQNLLKSFSKKGRPLVKKAM 181
+T ++D++ G+ H G +GY W++VK L+GI + LL SFSK R ++ A
Sbjct: 134 DTTMMDNMARFGWKHGGFTVGYESVVNRWNFVKGLDGIHNEKELLASFSKYRRKNIRIAQ 193
Query: 182 SFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFRE 241
G+++R L+R EL F + ++ R+ + + L YY+ +D+FGD EF + +F E
Sbjct: 194 DSGLRVRRLERGELSTFVKLCDMSAARQGFKSRDLAYYERLFDTFGDLIEFKVVETHFDE 253
Query: 242 YDHNLQ--LN-AKKLEEQITVLDNRHQNN---------TDSAKYHRQRTELVNQLASLDK 289
Y LQ LN A K + + L R Q +D A ++ ++A+L+K
Sbjct: 254 YLDTLQSKLNAASKDKRNLERLLQRAQQQPEGTAKKGASDPATLEKRIATADKKIAALEK 313
Query: 290 RRKEVEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEAL 349
EV I G V AG ++ + P E V L SG F +Y +++ M + +
Sbjct: 314 TIGEVNGIIASDGPVIPVEAG-VYFWHPNEVVCLSSGEDDRFMDYYPSSLIHFEAMLDCI 372
Query: 350 KRQSTFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKK 406
R +NF GI G FD +D GV +FK F G++ G F + L++ + K
Sbjct: 373 ARGVERFNFYGISGIFDANDPSYGVWQFKTRFGGFVEELPGKFTLPVDGLRFGVSEAAHK 432
Query: 407 ILRR 410
+L R
Sbjct: 433 LLHR 436
>gi|23464884|ref|NP_695487.1| FemAB-like protein possibly involved
in interpeptide bridge formation in peptidoglycan
[Bifidobacterium longum NCC2705]
gi|23325474|gb|AAN24123.1|AE014647_2 FemAB-like protein possibly
involved in interpeptide bridge formation in
peptidoglycan [Bifidobacterium longum NCC2705]
Length = 436
Score = 158 bits (400), Expect = 2e-37
Identities = 121/424 (28%), Positives = 199/424 (46%), Gaps = 20/424 (4%)
Query: 5 ELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTG 64
++T E +++S SF QT +MA + G + Y+G + K+ V
Sbjct: 15 KITPAELDAFSAAQVQGSFQQTSQMAAMGAFNG-PVDYVGVKRGDKLIAACYVVYTRSRF 73
Query: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGAP 122
GL V GP + N + ++ + L+ AK+ A+ + P Y+ +GKP P
Sbjct: 74 GLEGSVWCGPLCDYDNPQVVEAMTEALRRSAKAHHAISVSCWPAAVYRLHDLDGKPTSDP 133
Query: 123 NTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGI-TPQNLLKSFSKKGRPLVKKAM 181
+T ++D++ G+ H G +GY W++VK L+ I + LL SFSK R ++ A
Sbjct: 134 DTTMMDNMARFGWKHGGFTVGYESVVNRWNFVKGLDCIHNEKELLASFSKYRRKNIRIAQ 193
Query: 182 SFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFRE 241
G+++R L+R EL F + ++ R+ + + L YY+ +D+FGD EF + +F E
Sbjct: 194 DSGLRVRRLERGELSTFVKLCDMSAARQGFKSRDLAYYERLFDTFGDLIEFKVVETHFDE 253
Query: 242 YDHNLQ--LN-AKKLEEQITVLDNRHQNN---------TDSAKYHRQRTELVNQLASLDK 289
Y LQ LN A K + + L R Q +D A ++ ++A+L+K
Sbjct: 254 YLDTLQSKLNAASKDKRNLERLLQRAQQQPEGTAKKGASDPATLEKRIATADKKIAALEK 313
Query: 290 RRKEVEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEAL 349
EV I G V AG ++ + P E V L SG F +Y +++ M + +
Sbjct: 314 TIGEVNGIIASDGPVIPVEAG-VYFWHPNEVVCLSSGEDDRFMDYYPSSLIHFEAMLDCI 372
Query: 350 KRQSTFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKK 406
R +NF GI G FD +D GV +FK F G++ G F + L++ + K
Sbjct: 373 ARGVERFNFYGISGIFDANDPSYGVWQFKTRFGGFVEELPGKFTLPVDGLRFGVSEAAHK 432
Query: 407 ILRR 410
+L R
Sbjct: 433 LLHR 436
>gi|4929303|gb|AAD33942.1|AF144663_1 factor essential for
methicillin resistance [Staphylococcus warneri]
Length = 418
Score = 151 bits (381), Expect = 2e-35
Identities = 121/419 (28%), Positives = 195/419 (45%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF ++ F Q +L G + +G + + I + + T
Sbjct: 1 MKFTNLTAKEFGDFTDQMPYTHFTQMVGNYELKLAEGTESHLVGIKNNDNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L L + PY YQ +G
Sbjct: 61 VPVMKFFKYFYTNRGPVIDYDNKELVHFFFNELSKYVKKHHCLYLRVDPYLPYQYRNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
G A N ++ D L S+G+ H+G H G+ P + H V NL+G T +++L +
Sbjct: 121 DITGNAGNDWIFDKLASLGFKHEGFHNGFDPILQVRHHSVLNLKGKTAKDVLNDMDNLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K++ L +EL IF+ TS+ + ++D+ YY D Y F D+ +
Sbjct: 181 RNTKKVQKNGVKVKFLSEDELPIFRSFMEDTSESKAFLDRDDSYYYDRYKHFKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L + L + + + D+ K H ++ L QLA+ ++ E
Sbjct: 241 AYINFDEYLEELNNEKETLTKDLNKALKDIEKRPDNKKSHNKKANLEQQLAANQQKIDEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ + GN+ + AG FI +P E VY G+ ++ F +Q ++ AL
Sbjct: 301 KQLQAEHGNELPISAGYFFI-NPFEVVYYAGGTSNKYRHFAGSYAVQWTMINYALDHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF GI G+F D D GV++FK+ +N ++ +G F N Y LKK+L++
Sbjct: 360 RYNFYGISGDFSEDAEDAGVIKFKKGYNADVIEYVGDFIKPINKPMYTVYTTLKKLLKK 418
>gi|1762962|gb|AAB52984.1| FemA
Length = 418
Score = 150 bits (379), Expect = 4e-35
Identities = 120/419 (28%), Positives = 198/419 (46%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LT EF ++ F Q +L G + +G + I + + T
Sbjct: 1 MKFTNLTTAEFGDFTDKMPYSHFTQMVGNYELKVAEGTETHLVGVKDKDDNVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + +F++EL+ Y K AL L + PY YQ +G
Sbjct: 61 VPVMKFFKYFYSNRGPVIDYDNKELVHYFFRELKAYVKQYNALYLRVDPYLPYQYRNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A + ++ D + +GY H G G+ P + +H V +L+ TPQ++LK +
Sbjct: 121 EITGNAGHDWIFDKMEQLGYIHQGFTTGFDPIIQIRFHSVLDLKDKTPQDVLKGMDSLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L +E+HIF+ T++ +D+ D+ D+Y + ++ +
Sbjct: 181 RNTKKVKRNGVKVRFLGEDEMHIFRKFMEDTAEAKDFDDREDDFYYHRLKHYKNRVLVPM 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A ++F +Y + L K LE++I + N ++ K R++ L QL + ++ E
Sbjct: 241 AYIDFEDYINELNAEQKNLEKEINKAEKDLNKNPENQKAARKKENLEQQLEAHHQKVAEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
QK GN+ + AG FI +P E VY G+ E+ F +Q ++ A+
Sbjct: 301 RDLQQKHGNELPISAG-FFIINPFEVVYYAGGTANEYRHFAGSYAVQWEMINYAINHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF GI G+F D D GV++FK+ FN ++ +G F N YK LKKI R
Sbjct: 360 RYNFYGISGHFTEDAEDAGVVKFKKGFNADVIEYVGDFIAPINKPMYKLYTTLKKIKDR 418
>gi|4539616|gb|AAD22133.1|U23712_1 FEMB [Staphylococcus
haemolyticus]
Length = 419
Score = 149 bits (375), Expect = 1e-34
Identities = 120/417 (28%), Positives = 195/417 (45%), Gaps = 14/417 (3%)
Query: 1 MALKELTAKEFESYSGNYDLQS-FMQTPEMAKLLKKRGYDITYMGYQIDG-KMEIISIVY 58
M ELT KEFE++ N L+S + Q E + + G+++ +G + + K+ S+
Sbjct: 1 MKFTELTVKEFENFVQNPSLESHYFQMKENIQTRENDGFEVVLLGVKDESNKVLAASLFS 60
Query: 59 TIPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
IP G N GP +S+ + + +EL+ Y L + I PY YQ + +
Sbjct: 61 KIPTMGSYVYYSNRGPVMDYSDLGLVDFYLRELEKYLHQHQCLYVKIDPYWIYQIYDKDI 120
Query: 117 KP--KGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKG 173
P N +++ S GY H G Y + W V L+G TP +L K F +
Sbjct: 121 NPLEDREKNDAIVNLFKSHGYEHHGFTTEYDTSSQARWMGVSYLKGETPASLRKQFDSQR 180
Query: 174 RPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFV 233
+ + KA+++G+K+R L R+E HIF D+ T R ++ K+ +Y+ +F+D++GDK
Sbjct: 181 KRNINKAINYGVKVRFLGRDEFHIFLDLYRETEARTGFVSKTDEYFYNFFDTYGDKVLVP 240
Query: 234 IATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKE 293
+A ++ EY +LQ L ++ D + K R+ EL NQ+ K +
Sbjct: 241 LAYIDLDEYIKSLQ---DALNDKENRRDQMMAKENKNDKQLRKIAELDNQIEHDKKELLQ 297
Query: 294 VEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
Q G Q + LA +F + E Y GS ++N + P ++ ++M +
Sbjct: 298 ASELRQTDG-QILNLASGIFFANSYEVNYFSGGSSEKYNNYMGPYMMHWHMMNYCFEHGY 356
Query: 354 TFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF G+ G+F + GV RFK+ FN YI +G F N +KY L I
Sbjct: 357 DRYNFYGLSGDFTENSEDYGVYRFKRGFNVYIEELIGDFYKPINKVKYWLFNTLNTI 413
>gi|27467976|ref|NP_764613.1| FemB protein [Staphylococcus
epidermidis ATCC 12228]
gi|27315521|gb|AAO04655.1|AE016747_152 FemB protein [Staphylococcus
epidermidis ATCC 12228]
Length = 417
Score = 141 bits (355), Expect = 2e-32
Identities = 113/415 (27%), Positives = 191/415 (45%), Gaps = 12/415 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQS-FMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT 59
M ELT KEFE++ N L+S + Q E + + G+ + +G + D I + +++
Sbjct: 1 MKFTELTVKEFENFVQNPSLESHYFQVKENIAIRESDGFQVVLLGVKDDDNRVIAASLFS 60
Query: 60 -IPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
IP G N GP +S+ + + KEL Y L + + PY YQ + +
Sbjct: 61 KIPTMGSYVYYSNRGPVMDYSDLGLVDFYLKELDKYLHQHQCLYVKLDPYWLYQVYDKDI 120
Query: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGRP 175
P N L++ S GY H G Y + W V +LEG TP +L K F + +
Sbjct: 121 NPLTEKNDALVNLFKSHGYDHHGFTTQYDSSSQVRWMGVLDLEGKTPASLRKEFDSQRKR 180
Query: 176 LVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIA 235
+ KA+++G+K+R L ++E +F D+ T R + K+ DY+ +F + +GDK +A
Sbjct: 181 NINKAINYGVKVRFLSKDEFDLFLDLYRETEARTGFASKTDDYFYNFIEHYGDKVLVPLA 240
Query: 236 TLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVE 295
++ EY +LQ + L ++ D+ + K ++ EL Q+ K +
Sbjct: 241 YIDLNEYIQHLQ---ESLNDKENRRDDMMAKENKTDKQLKKIAELDKQIDHDKKELLQAS 297
Query: 296 PFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTF 355
Q G + + LA ++ + E Y GS ++N++ P + +++
Sbjct: 298 ELRQTDG-EILNLASGVYFANAYEVNYFSGGSSEKYNQYMGPYAMHWHMINYCFDNGYDR 356
Query: 356 YNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF G+ G+F + GV RFK+ FN I +G F N +KY L +I
Sbjct: 357 YNFYGLSGDFTENSEDYGVYRFKRGFNVRIEELIGDFYKPINKVKYWLFNTLDRI 411
>gi|7448859|pir||JC5326 methicillin resistance factor FEMB -
Staphylococcus epidermidis
gi|1815620|gb|AAB41948.1| FEMB [Staphylococcus epidermidis]
Length = 417
Score = 139 bits (351), Expect = 6e-32
Identities = 113/415 (27%), Positives = 190/415 (45%), Gaps = 12/415 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQS-FMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT 59
M ELT KEFE++ N L+S + Q E + G+ + +G + D I + +++
Sbjct: 1 MKFTELTVKEFENFVQNPSLESHYFQVKENIATRESDGFQVVLLGVKDDDNRVIAASLFS 60
Query: 60 -IPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
IP G N GP +S+ + + KEL Y L + + PY YQ + +
Sbjct: 61 KIPTMGSYVYYSNRGPVMDYSDLGLVDFYLKELDKYLHQHQCLYVKLDPYWLYQVYDKDI 120
Query: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGRP 175
P N L++ S GY H G Y + W V +LEG TP +L K F + +
Sbjct: 121 NPLTEKNDALVNLFKSHGYDHHGFTTQYDSSSQVRWMGVLDLEGKTPASLRKEFDSQRKR 180
Query: 176 LVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIA 235
+ KA+++G+K+R L ++E +F D+ T R + K+ DY+ +F + +GDK +A
Sbjct: 181 NINKAINYGVKVRFLSKDEFGLFLDLYRETEARTGFASKTDDYFYNFIEHYGDKVLVPLA 240
Query: 236 TLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVE 295
++ EY +LQ + L ++ D+ + K ++ EL Q+ K +
Sbjct: 241 YIDLNEYIQHLQ---ESLNDKENRRDDMMAKENKTDKQLKKIAELDKQIDHDKKELLQAS 297
Query: 296 PFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTF 355
Q G + + LA ++ + E Y GS ++N++ P + +++
Sbjct: 298 ELRQTDG-EILNLASGVYFANAYEVNYFSGGSSEKYNQYMGPYAMHWHMINYCFDNGYDR 356
Query: 356 YNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF G+ G+F + GV RFK+ FN I +G F N +KY L +I
Sbjct: 357 YNFYGLSGDFTENSEDYGVYRFKRGFNVRIEELIGDFYKPINKVKYWLFNTLDRI 411
>gi|2462668|emb|CAA73372.1| femA [Staphylococcus hominis]
Length = 420
Score = 139 bits (349), Expect = 1e-31
Identities = 115/419 (27%), Positives = 190/419 (44%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQ-IDGKMEIISIVYT 59
M LTA EF ++ F Q E +L + +G + D ++ ++
Sbjct: 1 MKFTNLTATEFGDFTEKMPYSHFTQMTENYELKVAEKTETHLVGIKNKDNEVIAACMLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K Q L + I PY YQ +G
Sbjct: 61 VPVMKIFKYFYSNRGPVIDYENKELVHFFFNELSKYLKQQHCLYVRIDPYLPYQYRNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
G A N + D + +GY H+G G+ P + +H V NL+ T +++L +
Sbjct: 121 DITGNAGNDWFFDKMKQLGYQHEGFTTGFDPILQIRFHSVLNLKDKTAKDVLNGMDSLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L +EEL IF+ TS+ +++ D+ +Y + +D F D+ +
Sbjct: 181 RNTKKVQKNGVKVRFLTKEELPIFRSFMEDTSETKEFSDREDSFYYNRFDHFKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A + F EY L + L + + + D+ K ++ L QL + +++ E
Sbjct: 241 AYIKFDEYLEELHAERQTLNKDLNKALKDIEKRPDNKKAQNKKINLEQQLKANEQKIDEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ GN+ + AG FI +P E VY G+ ++ F +Q ++ A+
Sbjct: 301 TQLQLEHGNELPISAGFFFI-NPFEVVYYAGGTSNKYRHFAGSYAVQWTMINYAIDHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF GI G+F D D GV++FK+ FN ++ +G F N Y LKKI +R
Sbjct: 360 RYNFYGISGHFTDDAEDAGVVKFKKGFNADVIEYVGDFVKPINKPMYSLYTTLKKIKKR 418
>gi|15924365|ref|NP_371899.1| FemB protein [Staphylococcus aureus
subsp. aureus Mu50]
gi|15926955|ref|NP_374488.1| FemB protein [Staphylococcus aureus
subsp. aureus N315]
gi|119903|sp|P14305|FEMB_STAAM Possible protein femB (ORF 419)
gi|79865|pir||S06784 hypothetical protein (femA 3' region) -
Staphylococcus aureus
gi|46582|emb|CAA35680.1| ORF 419 protein [Staphylococcus aureus]
gi|13701172|dbj|BAB42467.1| FemB protein [Staphylococcus aureus
subsp. aureus N315]
gi|14247146|dbj|BAB57537.1| FemB protein [Staphylococcus aureus
subsp. aureus Mu50]
Length = 419
Score = 137 bits (344), Expect = 5e-31
Identities = 113/411 (27%), Positives = 194/411 (46%), Gaps = 20/411 (4%)
Query: 1 MALKELTAKEFESYSGNYDLQS-FMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT 59
M ELT EF+++ N L+S + Q E + G+++ +G + D I + +++
Sbjct: 1 MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFS 60
Query: 60 -IPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTG-- 114
IP G N GP S+ + ++ KEL Y + L + + PY Y +
Sbjct: 61 KIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDI 120
Query: 115 ---EGKPKGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFS 170
EG+ K N L++ S GY H G Y + W V NLEG TP+ L K+F
Sbjct: 121 VPFEGREK---NDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFD 177
Query: 171 KKGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKA 230
+ + + KA+++G+K+R L+R+E ++F D+ T +R ++ K+ DY+ +F D++GDK
Sbjct: 178 SQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKV 237
Query: 231 EFVIATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKR 290
+A ++ EY LQ ++L ++ D S K ++ EL Q+ D+
Sbjct: 238 LVPLAYIDLDEYVLKLQ---QELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDH-DQH 293
Query: 291 RKEVEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALK 350
+ K + LA ++ + E Y GS ++N+F P ++ +++
Sbjct: 294 ELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFD 353
Query: 351 RQSTFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKY 398
YNF G+ G+F + GV RFK+ FN I +G F + +KY
Sbjct: 354 NGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKY 404
>gi|4539614|gb|AAD22132.1|U23711_1 FEMA [Staphylococcus
haemolyticus]
Length = 420
Score = 136 bits (343), Expect = 6e-31
Identities = 111/419 (26%), Positives = 191/419 (45%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQ-IDGKMEIISIVYT 59
M LTA EF +Y+ F Q E ++ + +G + D ++ ++
Sbjct: 1 MKFTNLTATEFGNYTDKMPYSHFTQMTENYEMKGANKTETHLVGIKNKDNEVIAACMLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L + + PY YQ +G
Sbjct: 61 VPVMKFFKYFYSNRGPVIDYDNRELVHFFFNELTKYLKQHNCLYVRVDPYLPYQYLNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A N + D + +G+ H+G G+ P + +H V +L+ T +++L +
Sbjct: 121 EITGNAGNDWFFDKMKHLGFEHEGFTKGFDPIKQIRYHSVLDLKNKTSKDILNGMDSLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K++ L EEL IF+ T++ +++ D+ +Y + Y F D+ +
Sbjct: 181 RNTKKVQKNGVKVKFLSEEELPIFRSFMEDTTETKEFQDRDDSFYYNRYRHFKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A + F EY LQ + L + + + D+ K ++ L QL + ++ E
Sbjct: 241 AYIKFDEYIEELQNERETLNKDVNKALKDIEKRPDNKKAFNKKENLEKQLDANQQKLDEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ + GN+ + AG FI +P E VY G+ ++ F +Q ++ A+
Sbjct: 301 KKLQAEHGNELPISAGFFFI-NPFEVVYYAGGTSNKYRHFAGSYAIQWTMINYAIDHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF GI GNF D D GV++FK+ FN ++ +G F N Y + LKKI +R
Sbjct: 360 RYNFYGISGNFSEDAEDVGVIKFKKGFNADVIEYVGDFVKPINKPLYSVYKTLKKIKKR 418
>gi|3820632|gb|AAC69635.1| factor essential for methicillin
resistance FEMA [Staphylococcus sciuri]
Length = 417
Score = 136 bits (342), Expect = 8e-31
Identities = 114/420 (27%), Positives = 198/420 (47%), Gaps = 13/420 (3%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVY 58
M LT EFE+++ F Q +L G +G + D + E+++ ++
Sbjct: 1 MKFTNLTTLEFEAFTNKMPYAHFTQAVGNYELKTSEGTSTHLVGVK-DNQGEVLAACLLT 59
Query: 59 TIPMTGGL-HMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGE 115
++P+ + N GP + N + + F+KE+ +Y KS L I PY YQ +
Sbjct: 60 SVPVMKKFNYFYSNRGPVMDYDNKELVDFFFKEIVSYLKSYKGLFFRIDPYLPYQLRDHD 119
Query: 116 GKPKGAPN-TYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKG 173
G K + N LI S+GY H G G+ P + WH V +LE + + L+K+
Sbjct: 120 GNIKKSFNRDGLIKQFESLGYEHQGFTTGFHPIHQIRWHSVLDLESMDEKTLIKNMDSLR 179
Query: 174 RPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFV 233
+ KK G+K+R L ++E+ IF+ T++++D+ D+ D+Y + F + +
Sbjct: 180 KRNTKKVQKNGVKVRFLSKDEMPIFRQFMEDTTEKKDFNDRGDDFYYNRLKYF-ENVKIP 238
Query: 234 IATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKE 293
+A ++F Y L+ ++ + I + + D+ K + L Q + + + +E
Sbjct: 239 LAYIDFETYIPQLEKEHEQYNKDIAKAEKDLEKKPDNQKTINKIDNLKQQREANEAKLEE 298
Query: 294 VEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
Q+ G+ + AG FI +P E VY GS E+ F +Q +++ AL
Sbjct: 299 ALQLQQEHGDTLPIAAG-FFIINPFEVVYYAGGSSNEYRHFAGSYAIQWEMIKYALDHNI 357
Query: 354 TFYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF GI G+F D D GV++FK+ +N + +G F N YK+ LKK+L++
Sbjct: 358 DRYNFYGISGDFSEDAPDVGVIKFKKGYNADVYEYIGDFVKPINKPAYKAYTTLKKVLKK 417
>gi|3820624|gb|AAC69631.1| factor essential for methicillin
resistance FEMA [Staphylococcus haemolyticus]
Length = 420
Score = 135 bits (339), Expect = 2e-30
Identities = 111/419 (26%), Positives = 190/419 (44%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQ-IDGKMEIISIVYT 59
M LTA EF +Y+ F Q E ++ + +G + D ++ ++
Sbjct: 1 MKFTNLTATEFGNYTDKMPYSHFTQMTENYEMKVANKTETHLVGIKNKDNEVIAACMLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L + + PY YQ +G
Sbjct: 61 VPVMKFFKYFYSNRGPVIDYDNRELVHFFFNELTKYLKQHNCLYVRVDPYLPYQYLNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A N + D + +G+ H+G G+ P + +H V +L+ T +++L +
Sbjct: 121 EITGNAGNDWFFDKMKHLGFEHEGFTKGFDPIKQIRYHSVLDLKNKTSKDILNGMDSLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K++ L EEL IF+ T++ +++ D+ +Y + Y F D +
Sbjct: 181 RNTKKVQKNGVKVKFLSEEELPIFRSFMEDTTETKEFQDRDDSFYYNRYRHFKDHVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A + F EY LQ + L + + + D+ K ++ L QL + ++ E
Sbjct: 241 AYIKFDEYIEELQNERETLNKDVNKALKDIEKRPDNKKAFNKKENLEKQLDANQQKLDEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ + GN+ + AG FI +P E VY G+ ++ F +Q ++ A+
Sbjct: 301 KKLQAEHGNELPISAGFFFI-NPFEVVYYAGGTSNKYRHFAGSYAIQWTMINYAIDHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF GI GNF D D GV++FK+ FN ++ +G F N Y + LKKI +R
Sbjct: 360 RYNFYGISGNFSEDAEDVGVIKFKKGFNADVIEYVGDFVKPINKPLYSVYKTLKKIKKR 418
>gi|119902|sp|P14304|FEMA_STAAW Factor essential for expression of
methicillin resistance
gi|79862|pir||S06783 femA protein - Staphylococcus aureus
gi|46581|emb|CAA35679.1| FemA protein [Staphylococcus aureus]
Length = 433
Score = 135 bits (339), Expect = 2e-30
Identities = 118/419 (28%), Positives = 196/419 (46%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF +++ + F QT +L GY+ +G + + I + + T
Sbjct: 14 MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKNNNNEVIAACLLTA 73
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L L I PY YQ +G
Sbjct: 74 VPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHIDPYLPYQYLNHDG 133
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A N + D ++++G+ H G H G+ P + +H V +L+ T +++K+ +
Sbjct: 134 EITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKTADDIIKNMDGLRK 193
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L EEL IF+ TS+ + + D+ +Y + + D+ +
Sbjct: 194 RNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSESKAFADRDDKFYYNRLKYYKDRVLVPL 253
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L L + + + ++ K H +R L QL + +++ +E
Sbjct: 254 AYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQQQLDANEQKIEEG 313
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ ++ GN+ + AG FI +P E VY G+ F F +Q ++ AL
Sbjct: 314 KRLQEEHGNELPISAGFFFI-NPFEVVYYAGGTSNAFRHFAGSYAVQWEMINYALNHGID 372
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF G+ G F D D GV++FK+ +N I+ +G F N Y + LKK+ R
Sbjct: 373 RYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYAAYTALKKVKDR 431
>gi|21282991|ref|NP_646079.1| FemB protein [Staphylococcus aureus
subsp. aureus MW2]
gi|21204430|dbj|BAB95127.1| FemB protein [Staphylococcus aureus
subsp. aureus MW2]
Length = 419
Score = 134 bits (338), Expect = 2e-30
Identities = 112/411 (27%), Positives = 193/411 (46%), Gaps = 20/411 (4%)
Query: 1 MALKELTAKEFESYSGNYDLQS-FMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT 59
M ELT EF+++ N L+S + Q E + G+++ +G + D I + +++
Sbjct: 1 MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFS 60
Query: 60 -IPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTG-- 114
IP G N GP S+ + ++ KEL Y + L + + PY Y +
Sbjct: 61 KIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDI 120
Query: 115 ---EGKPKGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFS 170
EG+ K N L++ S GY H G Y + W V NLEG TP+ L K+F
Sbjct: 121 VPFEGREK---NDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFD 177
Query: 171 KKGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKA 230
+ + + KA+++G+K+R L+ +E ++F D+ T +R ++ K+ DY+ +F D++GDK
Sbjct: 178 SQRKRNINKAINYGVKVRFLESDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKV 237
Query: 231 EFVIATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKR 290
+A ++ EY LQ ++L ++ D S K ++ EL Q+ D+
Sbjct: 238 LVPLAYIDLDEYVLKLQ---QELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDH-DQH 293
Query: 291 RKEVEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALK 350
+ K + LA ++ + E Y GS ++N+F P ++ +++
Sbjct: 294 ELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFD 353
Query: 351 RQSTFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKY 398
YNF G+ G+F + GV RFK+ FN I +G F + +KY
Sbjct: 354 NGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKY 404
>gi|3820626|gb|AAC69632.1| factor essential for methicillin
resistance FEMA [Staphylococcus lugdunensis]
Length = 419
Score = 134 bits (337), Expect = 3e-30
Identities = 112/416 (26%), Positives = 189/416 (44%), Gaps = 10/416 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTA EF ++ F Q L + +G + + I + + T
Sbjct: 1 MKFTNLTANEFGDFTDQMPYSHFTQMTGNYNLKVAEKTETHLVGVKNNNNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP ++N + + F+ EL Y K L + I PY YQ +G
Sbjct: 61 VPVMKFFKYFYSNRGPVIDYANQELVHFFFNELTKYLKKYNCLYVRIDPYLPYQYRDHDG 120
Query: 117 K-PKGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
A N + + + +GYHHDG G+ P + +H + NL+ T +++L + +
Sbjct: 121 NITANAGNDWFFNKMEQLGYHHDGFTTGFDPILQIRFHSILNLKDKTAKDVLNNMDSLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK+ G+K++ L EEL IF+ TS+ +++ D+ +Y + + + D+ +
Sbjct: 181 RNTKKSSKNGVKVKFLTEEELPIFRSFMEQTSESKEFSDRDDQFYYNRFKYYKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A L F EY L + LE+ + + D+ K + +R L QL + ++ E
Sbjct: 241 AYLKFDEYIEELTNERQTLEKDLGKALKDIEKRPDNKKAYNKRDNLQQQLDANQQKLNEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ GN+ + AG FI +P E VY G+ ++ F +Q ++ A++
Sbjct: 301 NQLQAEHGNELPISAG-FFIINPFEVVYYAGGTANKYRHFAGSYAVQWTMINYAIEHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI GNF D D GV+RFK+ + ++ +G F N YK +LK+I
Sbjct: 360 RYNFYGISGNFSDDAEDAGVIRFKKGYGAEVIEYVGDFVKPINKPMYKLYSVLKRI 415
>gi|4929299|gb|AAD33940.1|AF144661_1 factor essential for
methicillin resistance [Staphylococcus aureus subsp.
anaerobius]
Length = 420
Score = 134 bits (337), Expect = 3e-30
Identities = 118/419 (28%), Positives = 196/419 (46%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF +++ + F QT +L GY+ +G + + I + + T
Sbjct: 1 MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKNNNNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L L I PY YQ +G
Sbjct: 61 VPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHIDPYLPYQYLNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A N + D ++++G+ H G H G+ P + +H V +L+ T +++K+ +
Sbjct: 121 EITGNAGNGWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKTADDIIKNMDGLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L EEL IF+ TS+ + + D+ +Y + + D+ +
Sbjct: 181 RNTKKVKKNGVKVRYLSEEELPIFRSFMEDTSESKAFADRDDKFYYNRLKYYKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L L + + + ++ K H +R L QL + +++ +E
Sbjct: 241 AYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQQQLDANEQKIEEG 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ ++ GN+ + AG FI +P E VY G+ F F +Q ++ AL
Sbjct: 301 KRLQEEHGNELPISAGFFFI-NPFEVVYYAGGTSNAFRHFAGSYAVQWEMINYALNHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF G+ G F D D GV++FK+ +N I+ +G F N Y + LKK+ R
Sbjct: 360 RYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPSNKPVYTAYTALKKVKDR 418
>gi|23200368|pdb|1LRZ|A Chain A, X-Ray Crystal Structure Of
Staphylococcus Aureus Fema
Length = 426
Score = 134 bits (337), Expect = 3e-30
Identities = 118/419 (28%), Positives = 196/419 (46%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF +++ + F QT +L GY+ +G + + I + + T
Sbjct: 1 MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKNNNNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L L I PY YQ +G
Sbjct: 61 VPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHIDPYLPYQYLNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A N + D ++++G+ H G H G+ P + +H V +L+ T +++K+ +
Sbjct: 121 EITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKTADDIIKNMDGLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L EEL IF+ TS+ + + D+ +Y + + D+ +
Sbjct: 181 RNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSESKAFADRDDKFYYNRLKYYKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L L + + + ++ K H +R L QL + +++ +E
Sbjct: 241 AYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQQQLDANEQKIEEG 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ ++ GN+ + AG FI +P E VY G+ F F +Q ++ AL
Sbjct: 301 KRLQEEHGNELPISAGFFFI-NPFEVVYYAGGTSNAFRHFAGSYAVQWEMINYALNHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF G+ G F D D GV++FK+ +N I+ +G F N Y + LKK+ R
Sbjct: 360 RYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYAAYTALKKVKDR 418
>gi|21282990|ref|NP_646078.1| factor essential for expression of
methicillin resistance [Staphylococcus aureus subsp.
aureus MW2]
gi|21204429|dbj|BAB95126.1| factor essential for expression of
methicillin resistance [Staphylococcus aureus subsp.
aureus MW2]
Length = 420
Score = 134 bits (337), Expect = 3e-30
Identities = 118/419 (28%), Positives = 196/419 (46%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF +++ + F QT +L GY+ +G + + I + + T
Sbjct: 1 MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKNNNNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L L I PY YQ +G
Sbjct: 61 VPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHIDPYLPYQYLNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A N + D ++++G+ H G H G+ P + +H V +L+ T +++K+ +
Sbjct: 121 EITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKTADDIIKNMDGLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L EEL IF+ TS+ + + D+ +Y + + D+ +
Sbjct: 181 RNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSESKAFADRDDKFYYNRLKYYKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L L + + + ++ K H +R L QL + +++ +E
Sbjct: 241 AYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQQQLDANEQKIEEG 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ ++ GN+ + AG FI +P E VY G+ F F +Q ++ AL
Sbjct: 301 KRLQEEHGNELPISAGFFFI-NPFEVVYYAGGTSNAFRHFAGSYAVQWEMINYALNHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF G+ G F D D GV++FK+ +N I+ +G F N Y + LKK+ R
Sbjct: 360 RYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYAAYTALKKVKDR 418
>gi|15924364|ref|NP_371898.1| factor essential for expression of
methicillin resistance [Staphylococcus aureus subsp.
aureus Mu50]
gi|15926954|ref|NP_374487.1| factor essential for expression of
methicillin resistance [Staphylococcus aureus subsp.
aureus N315]
gi|25320224|pir||F89913 hypothetical protein femA [imported] -
Staphylococcus aureus (strain N315)
gi|13701171|dbj|BAB42466.1| factor essential for expression of
methicillin resistance [Staphylococcus aureus subsp.
aureus N315]
gi|14247145|dbj|BAB57536.1| factor essential for expression of
methicillin resistance [Staphylococcus aureus subsp.
aureus Mu50]
Length = 420
Score = 134 bits (336), Expect = 4e-30
Identities = 118/419 (28%), Positives = 196/419 (46%), Gaps = 10/419 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF +++ + F QT +L GY+ +G + + I + + T
Sbjct: 1 MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKNNNNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L L I PY YQ +G
Sbjct: 61 VPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHIDPYLPYQYLNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A N + D ++++G+ H G H G+ P + +H V +L+ T +++K+ +
Sbjct: 121 EITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKTADDIIKNMDGLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L EEL IF+ TS+ + + D+ +Y + + D+ +
Sbjct: 181 RNTKKVKKNGVKVRYLSEEELPIFRSFMEDTSESKAFADRDDKFYYNRLKYYKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L L + + + ++ K H +R L QL + +++ +E
Sbjct: 241 AYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQQQLDANEQKIEEG 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ ++ GN+ + AG FI +P E VY G+ F F +Q ++ AL
Sbjct: 301 KRLQEEHGNELPISAGFFFI-NPFEVVYYAGGTSNAFRHFAGSYAVQWEMINYALNHGID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
YNF G+ G F D D GV++FK+ +N I+ +G F N Y + LKK+ R
Sbjct: 360 RYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYAAYTALKKVKDR 418
>gi|3820628|gb|AAC69633.1| factor essential for methicillin
resistance FEMA [Staphylococcus capitis]
Length = 417
Score = 134 bits (336), Expect = 4e-30
Identities = 110/416 (26%), Positives = 190/416 (45%), Gaps = 10/416 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF ++ F Q +L G D +G + + I + + T
Sbjct: 1 MKFTNLTAKEFSDFTDQMPYSHFTQMEGNYELKVAEGTDSHLVGIKNNDNQVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K L L + PY YQ +G
Sbjct: 61 VPVMKIFKYFYSNRGPVIDYDNKELVHFFFNELSKYVKKHNCLYLRVDPYLPYQYLNHDG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A + + + + +G+ H+G H G+ P + +H V +L+ T +++LK +
Sbjct: 121 EIIGNAGHDWFFNKMEELGFEHEGFHKGFHPILQVRYHSVLDLKDKTAKDVLKGMDSLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L +EL IF+ T++ +++ D+ +Y + F D+ +
Sbjct: 181 RNTKKVQKNGVKVRFLSEDELPIFRSFMEDTTETKEFADRDDSFYYNRLKYFKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A ++F EY L L + + + D+ K + +R L QL + ++ E
Sbjct: 241 AYVDFDEYIEELNNERDVLNKDLNKALKDIEKRPDNKKAYNKRDNLQQQLDANQQKIDEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ Q+ GN+ + AG FI +P E VY G+ + + +Q ++ AL+
Sbjct: 301 KNLQQEHGNELPISAGYFFI-NPFEVVYYAGGTSNRYRHYAGSYAIQWKMINYALEHGIN 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF G+ G+F D D GV++FK+ +N ++ +G F N Y LKK+
Sbjct: 360 RYNFYGVSGDFSEDAEDVGVIKFKKGYNADVIEYVGDFIKPINKPMYAIYNALKKL 415
>gi|27467975|ref|NP_764612.1| methicillin resistance factor
[Staphylococcus epidermidis ATCC 12228]
gi|27315520|gb|AAO04654.1|AE016747_151 methicillin resistance
factor [Staphylococcus epidermidis ATCC 12228]
Length = 417
Score = 132 bits (333), Expect = 8e-30
Identities = 116/416 (27%), Positives = 194/416 (45%), Gaps = 10/416 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF ++ F Q +L G + +G + + I + + T
Sbjct: 1 MKFTNLTAKEFSDFTDRMTYSHFTQMEGNYELKVAEGTESHLVGIKNNDNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP ++N + + F+ EL Y K L L + PY YQ EG
Sbjct: 61 VPVMKIFKYFYSNRGPVIDYNNKELVHFFFNELSKYVKKYNCLYLRVDPYLPYQYLNHEG 120
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A + ++ D+L S+GY H+G H G+ P + +H V NL + ++LK+ +
Sbjct: 121 EITGNAGHDWIFDELESLGYKHEGFHKGFDPVLQIRYHSVLNLANKSANDVLKNMDGLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L EEL IF+ TS+ +D+ D+ +Y + + + D+ +
Sbjct: 181 RNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSETKDFADREDSFYYNRFKHYKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L L + + ++ K H ++ L QL + ++ E
Sbjct: 241 AYINFDEYIEELNNERNVLNKDYNKALKDIEKRPENKKAHNKKENLEQQLDANQQKINEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ Q+ GN+ + AG FI +P E VY G+ + F +Q ++ A++
Sbjct: 301 KNLKQEHGNELPISAG-FFIINPFEVVYYAGGTSNRYRHFAGSYAVQWKMINYAIEHGIN 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI G+F D D GV++FK+ ++ ++ +G F N Y + LKK+
Sbjct: 360 RYNFYGISGDFSEDAEDAGVVKFKKGYDADVIEYVGDFIKPINKPMYNIYRTLKKL 415
>gi|7448858|pir||JC5325 methicillin resistance factor FEMA -
Staphylococcus epidermidis
Length = 422
Score = 132 bits (333), Expect = 8e-30
Identities = 116/416 (27%), Positives = 194/416 (45%), Gaps = 10/416 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF ++ F Q +L G + +G + + I + + T
Sbjct: 6 MKFTNLTAKEFSDFTDRMTYSHFTQMEGNYELKVAEGTESHLVGIKNNDNEVIAACLLTA 65
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP ++N + + F+ EL Y K L L + PY YQ EG
Sbjct: 66 VPVMKIFKYFYSNRGPVIDYNNKELVHFFFNELSKYVKKYNCLYLRVDPYLPYQYLNHEG 125
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A + ++ D+L S+GY H+G H G+ P + +H V NL + ++LK+ +
Sbjct: 126 EITGNAGHDWIFDELESLGYKHEGFHKGFDPVLQIRYHSVLNLANKSANDVLKNMDGLRK 185
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L EEL IF+ TS+ +D+ D+ +Y + + + D+ +
Sbjct: 186 RNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSETKDFADREDSFYYNRFKHYKDRVLVPL 245
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L L + + ++ K H ++ L QL + ++ E
Sbjct: 246 AYINFDEYIEELNNERNVLNKDYNKALKDIEKRPENKKAHNKKENLEQQLDANQQKINEA 305
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ Q+ GN+ + AG FI +P E VY G+ + F +Q ++ A++
Sbjct: 306 KNLKQEHGNELPISAG-FFIINPFEVVYYAGGTSNRYRHFAGSYAVQWKMINYAIEHGIN 364
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI G+F D D GV++FK+ ++ ++ +G F N Y + LKK+
Sbjct: 365 RYNFYGISGDFSEDAEDAGVVKFKKGYDADVIEYVGDFIKPINKPMYNIYRTLKKL 420
>gi|5565907|gb|AAD45258.1|AF145332_1 methicillin resistance protein
FemA [Staphylococcus gallinarum]
Length = 420
Score = 131 bits (329), Expect = 2e-29
Identities = 112/417 (26%), Positives = 195/417 (45%), Gaps = 12/417 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVY 58
M LTAKEF +++ + F Q +L G + +G + + + E+I+ ++
Sbjct: 1 MKFTNLTAKEFGTFTDSMPNSHFTQMVGNYELKIAEGTETHLVGIK-NNENEVIAACLLT 59
Query: 59 TIP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGE 115
+P M + N GP N + + +F+ EL Y K AL L + PY YQ +
Sbjct: 60 AVPVMKYFKYFYTNRGPVIDFENKELVHYFFNELSKYVKKHRALYLRVDPYLPYQYRNHD 119
Query: 116 GKP-KGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKG 173
G + A + ++ D + +GY H G G+ P + +H V L+ T +++LK
Sbjct: 120 GDVLENAGHDWIFDKMKHLGYKHQGFLTGFDPVVQIRFHSVLELKDKTDKDVLKDMDGLR 179
Query: 174 RPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFV 233
+ KK G+K+R L +EL IF+ TS+ + + D+ +Y + + ++
Sbjct: 180 KRNTKKVQKNGVKVRFLGEDELPIFRAFMEDTSETKAFEDRDDSFYYNRLKYYKNRVLVP 239
Query: 234 IATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKE 293
+A ++F EY L + L + I + ++ K + +R L QL + ++ E
Sbjct: 240 LAYMDFDEYIEELTAEREVLSKDINKALKDIEKRPENKKAYNKRDNLEKQLIANQQKIDE 299
Query: 294 VEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
+ ++ GN+ + ++ + FI +P E VY G+ EF F +Q ++ AL
Sbjct: 300 AKALQKQHGNE-LPISAAFFIINPYEVVYYAGGTSNEFRHFAGSYAVQWTMINYALDNNI 358
Query: 354 TFYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI G+F D D GV++FK+ FN ++ +G F N YK LKK+
Sbjct: 359 DRYNFYGISGDFTEDAEDAGVVKFKKGFNADVIEYVGDFIKPINRPAYKIYTALKKL 415
>gi|4929301|gb|AAD33941.1|AF144662_1 factor essential for
methicillin resistance [Staphylococcus intermedius]
Length = 421
Score = 130 bits (327), Expect = 4e-29
Identities = 107/423 (25%), Positives = 199/423 (46%), Gaps = 15/423 (3%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVY 58
M LT EF +++ + F Q +L G + +G + D + ++++ ++
Sbjct: 1 MKFTNLTTAEFGAFTDSMPYSHFTQMVGNYELKVAEGVETHLVGIK-DNQNQVLAACLLT 59
Query: 59 TIP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGE 115
+P M + N GP + N + + F+ EL Y K AL + + PY + +
Sbjct: 60 AVPVMKVFKYFYTNRGPVMDYENQELVHFFFNELTKYVKKYNALYVRVDPYLPMLKRNHD 119
Query: 116 GKP-KGAPNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKG 173
G+ + N + D + +G+ H+G G+ + +H V ++EG T +++L +
Sbjct: 120 GEVIERFQNDWFFDKMAQLGFEHEGFTTGFDTVRQIRFHSVLDVEGKTAKDILNNMDSLR 179
Query: 174 RPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFV 233
+ KK G+K+R L ELHI + TS+ +D++D+ D+Y + D+
Sbjct: 180 KRNTKKVQKNGVKVRFLDENELHILRSFMEDTSETKDFVDREDDFYYHRLKHYKDRVLVP 239
Query: 234 IATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKE 293
+A ++F Y L+ + +QI + + D+ K ++ L+ QL + + +E
Sbjct: 240 LAYIDFTTYIPGLKSEEQDFHKQIAKTEKELEKRPDNQKALNKKKNLMQQLEANQAKIQE 299
Query: 294 VEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
E K G+ + AG FI +P E VY G+ EF F +Q ++ A++
Sbjct: 300 AEQLQAKHGDTLPISAG-FFIINPFEVVYYAGGTANEFRHFAGSYAVQWEMINYAIEHDI 358
Query: 354 TFYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTF-RYYPNPLK--YKSIQLLKKI 407
YNF GI G+F D D GV++FK+ +N ++ +G F + P+ Y +++ LKK
Sbjct: 359 PRYNFYGISGHFTEDAEDAGVVKFKKGYNADVIEYVGDFIKPVQKPVYKIYTTLKQLKKK 418
Query: 408 LRR 410
++R
Sbjct: 419 IKR 421
>gi|1815618|gb|AAB41947.1| FEMA [Staphylococcus epidermidis]
Length = 422
Score = 130 bits (326), Expect = 5e-29
Identities = 115/416 (27%), Positives = 193/416 (45%), Gaps = 10/416 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF ++ F Q +L G + +G + + I + + T
Sbjct: 6 MKFANLTAKEFSDFTDRMTYSHFTQMEGNYELKVAEGTESHLVGIKNNDNEVIAACLLTA 65
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP ++N + + F+ EL Y K L L + PY YQ EG
Sbjct: 66 VPVMKIFKYFYSNRGPVIDYNNKELVHFFFNELSKYVKKYNCLYLRVDPYLPYQYLNHEG 125
Query: 117 KPKG-APNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ G A + ++ D+L S+GY H+G H G+ P + +H V NL + ++LK+ +
Sbjct: 126 EITGNAGHDWIFDELESLGYKHEGFHKGFDPVLQIRYHSVLNLANKSANDVLKNMDGLRK 185
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L EEL IF+ TS+ +D+ D+ +Y + + + + +
Sbjct: 186 RNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSETKDFADREDSFYYNRFKHYKGRVLVPL 245
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +NF EY L L + + ++ K H ++ L QL + ++ E
Sbjct: 246 AYINFDEYIEELNNERNVLNKDYNKALKDIEKRPENKKAHNKKENLEQQLDANQQKINEA 305
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ Q+ GN+ + AG FI +P E VY G+ + F +Q ++ A++
Sbjct: 306 KNLKQEHGNELPISAG-FFIINPFEVVYYAGGTSNRYRHFAGSYAVQWKMINYAIEHGIN 364
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI G+F D D GV++FK+ ++ ++ +G F N Y + LKK+
Sbjct: 365 RYNFYGISGDFSEDAEDAGVVKFKKGYDADVIEYVGDFIKPINKPMYNIYRTLKKL 420
>gi|3820630|gb|AAC69634.1| factor essential for methicillin
resistance FEMA [Staphylococcus xylosus]
Length = 420
Score = 128 bits (321), Expect = 2e-28
Identities = 108/408 (26%), Positives = 186/408 (45%), Gaps = 10/408 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LT K ++S F Q +L + +G + + I + + T
Sbjct: 1 MKFTNLTQKSLGAFSDKMPNSHFTQMVGNYELKIAESTETHLVGIKNNDNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP N + + +F+ EL Y K AL L + PY YQ +G
Sbjct: 61 VPVMKFFKYFYTNRGPVIDFENKELVHYFFNELSKYVKKHNALYLRVDPYLAYQYRNHDG 120
Query: 117 KP-KGAPNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ + A + ++ D + +GY H G G+ + +H V +L G T +++L +
Sbjct: 121 EVLENAGHDWIFDKMKQLGYKHQGFLTGFDSIIQIRFHSVLDLVGKTAKDVLNGMDSLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L+ +EL IF+ TS+ +D+ D+ +Y + + D+ +
Sbjct: 181 RNTKKVQKNGVKVRFLREDELPIFRSFMEDTSETKDFDDRDDGFYYNRLRYYKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A ++F EY LQ + L + I + ++ K + ++ L QL + ++ E
Sbjct: 241 AYMDFNEYIEELQAEREVLSKDINKAVKDIEKRPENKKAYNKKDNLEKQLIANQQKIDEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+ +K GN+ + ++ + FI +P E VY G+ EF F +Q ++ A+
Sbjct: 301 KTLQEKHGNE-LPISAAYFIINPYEVVYYAGGTSNEFRHFAGSYAIQWKMINYAIDHNID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYK 399
YNF GI G+F D D GV++FK+ FN +V +G F N YK
Sbjct: 360 RYNFYGISGHFTEDAEDAGVVKFKKGFNADVVEYVGDFIKPINKPMYK 407
>gi|5565909|gb|AAD45259.1|AF145333_1 methicillin resistance protein
FemA [Staphylococcus cohnii subsp. urealyticus]
Length = 419
Score = 125 bits (315), Expect = 9e-28
Identities = 107/415 (25%), Positives = 193/415 (45%), Gaps = 12/415 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVY 58
M LTAKEF ++ + F Q +L G + +G + + + E+I+ ++
Sbjct: 1 MKFTNLTAKEFGAFVDHMPNSHFTQMVGNYELKIAEGTETHLVGVK-NNENEVIAACLLT 59
Query: 59 TIP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGE 115
+P M + N GP N + + +F+ EL Y K AL L + PY YQ +
Sbjct: 60 AVPVMKIFKYFYTNRGPVIDFENKELVHYFFNELTKYVKKHNALYLRVDPYLAYQYRNHD 119
Query: 116 GKP-KGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKG 173
G + A + ++ D + +GY H G G+ P + +H V +L+ T +++L
Sbjct: 120 GDVLENAGHDWIFDKMKQLGYKHQGFLTGFDPIIQIRFHSVLDLKDKTAKDVLNDMDSLR 179
Query: 174 RPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFV 233
+ KK G+K+R L +EL IF+ TS+ +D+ D+ +Y + + ++
Sbjct: 180 KRNTKKVQKNGVKVRFLGEDELPIFRSFMEDTSESKDFDDREDSFYYNRLKYYKNRVLVP 239
Query: 234 IATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKE 293
+A ++F Y L+ + L + I ++ K + ++ L QL + ++ E
Sbjct: 240 LAYMDFEAYIDELKSEREVLSKDINKALKDIAKRPENKKAYNKKENLEKQLIANQQKIDE 299
Query: 294 VEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
+ ++ GN+ + ++ + FI +P E VY G+ EF F +Q ++ A+
Sbjct: 300 AKSLQEQHGNE-LPISAAFFIVNPYEVVYYAGGTSNEFRHFAGSYAIQWKMINYAIDNNI 358
Query: 354 TFYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLK 405
YNF GI G+F + D GV++FK+ FN +V +G F N YK ++K
Sbjct: 359 DRYNFYGISGDFSEEAEDAGVVKFKKGFNADVVEYVGDFIKPINKPMYKIYTMVK 413
>gi|3820634|gb|AAC69636.1| factor essential for methicillin
resistance FEMA [Staphylococcus schleiferi]
Length = 421
Score = 124 bits (312), Expect = 2e-27
Identities = 106/416 (25%), Positives = 186/416 (44%), Gaps = 10/416 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LT EF +++ F Q +L G + +G + + + + + T
Sbjct: 1 MKFTNLTTAEFGAFTDQMPYSHFTQMVGNYELKVAEGVETHLVGIKDNNNNVLAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP + N + + F+ EL Y K AL L + PY + +G
Sbjct: 61 VPVMKFFKYFYSNRGPVMDYENKELVHFFFNELSKYVKKYHALYLRVDPYLPMLKRNHDG 120
Query: 117 KP-KGAPNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ + + + D + + + H+G G+ + +H V ++E T +++L +
Sbjct: 121 EVIERYGSDWFFDKMAELNFEHEGFTTGFDTIRQIRFHSVLDVENKTSKDILNQMDNLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L +ELHIF+ TS+ +D++D+ D+Y + D+ +
Sbjct: 181 RNTKKVQKNGVKVRYLNEDELHIFRSFMEDTSETKDFVDRDDDFYYHRMKYYKDRVRVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A ++F Y L A+ +++I D ++ K ++ L QL + + KE
Sbjct: 241 AYIDFNAYLAELNTEAQDFKKEIAKADKDIDKRPENQKAINKKKNLEQQLEANQAKIKEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
E K G+ + AG FI +P E VY G+ EF F +Q ++ A+ Q
Sbjct: 301 ETLQLKHGDTLPISAG-FFIINPFEVVYYAGGTANEFRHFAGSYAVQWEMINYAIDYQIP 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI G+F D D GV++FK+ +N ++ +G F N Y LK++
Sbjct: 360 RYNFYGISGDFSEDAEDAGVIKFKKGYNAEVIEYVGDFIKPINKPAYTVYLKLKQL 415
>gi|2462697|emb|CAA73373.1| femA [Staphylococcus saprophyticus]
Length = 420
Score = 124 bits (311), Expect = 3e-27
Identities = 111/408 (27%), Positives = 189/408 (46%), Gaps = 10/408 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYT- 59
M LTAKEF +++ F Q +L + +G + + I + + T
Sbjct: 1 MKFTNLTAKEFGAFTDKMPNSHFTQMVGNYELKIAESTETHLVGIKNNDNEVIAACLLTA 60
Query: 60 IP-MTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P M + N GP N + + +F+ EL Y K AL L + PY YQ +G
Sbjct: 61 VPVMKFFKYFYSNRGPVIDFENKELVHYFFNELAKYVKKHNALYLRVDPYLAYQYRNHDG 120
Query: 117 KP-KGAPNTYLIDDLTSIGYHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ A + ++ D + +GY H+G G+ P + +H V +L G T +++L +
Sbjct: 121 EVLANAGHDWIFDKMKQLGYKHEGFLTGFDPILQIRFHSVLDLAGKTAKDVLNGMDSLRK 180
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
KK G+K+R L +EL IF+ TS+ +D+ D+ D+Y + + D+ +
Sbjct: 181 RNTKKVQKNGVKVRFLGEDELPIFRSFMEDTSETKDFDDRDDDFYYNRLRYYKDRVLVPL 240
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A ++F EY L+ + L + I + ++ K + ++ L QL + ++ E
Sbjct: 241 AYMDFDEYITELKAEREVLSKDINKAVKDIEKRPENKKAYNKKENLEQQLIANQQKIDEA 300
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
+K GN+ + ++ + FI +P E VY G+ EF F +Q ++ A+
Sbjct: 301 TALQEKHGNE-LPISAAYFIINPYEVVYYAGGTSNEFRHFAGSYAIQWKMINYAIDHNID 359
Query: 355 FYNFLGIQGNF--DGSD-GVLRFKQNFNGYIVRKMGTFRYYPNPLKYK 399
YNF GI G+F D D GV++FK+ FN +V +G F N YK
Sbjct: 360 RYNFYGISGHFTEDAEDAGVVKFKKGFNADVVEYVGDFIKPINKPMYK 407
>gi|15924238|ref|NP_371772.1| FmhC protein [Staphylococcus aureus
subsp. aureus Mu50]
gi|15926831|ref|NP_374364.1| FmhC protein [Staphylococcus aureus
subsp. aureus N315]
gi|25320221|pir||C89898 FmhC protein [imported] - Staphylococcus
aureus (strain N315)
gi|13701048|dbj|BAB42343.1| FmhC protein [Staphylococcus aureus
subsp. aureus N315]
gi|14247018|dbj|BAB57410.1| FmhC protein [Staphylococcus aureus
subsp. aureus Mu50]
Length = 414
Score = 122 bits (305), Expect = 1e-26
Identities = 108/416 (25%), Positives = 192/416 (45%), Gaps = 11/416 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M L+ +EF +Y+ + + + Q+ E+ K ++ +G + D I + + T
Sbjct: 1 MKFSTLSEEEFTNYTKKH-FKHYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTE 59
Query: 61 PMTGGLHMEVNS--GPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+ S GP + ++K + +F+KEL + + +L+ PY G
Sbjct: 60 ARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANG 119
Query: 117 K-PKGAPNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ K N+ ++ L IGY H G GY + W V +L+ LLK + R
Sbjct: 120 RIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTR 179
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
+KK + G+K+ L EE + F + ++ + + DY++ + + DKA I
Sbjct: 180 RNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKI 239
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +N EY L++ K+E ++ ++ N +S K + +L QL+S++ R +
Sbjct: 240 ACINLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKT 299
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
E I + G + LA +LFI + E YL SGS ++N++ LQ ++++ A
Sbjct: 300 EELILEDGPV-LDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNIN 358
Query: 355 FYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI G F GV +FK+ FN ++ +G F P+ YK +L+ K+
Sbjct: 359 RYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV 414
>gi|21282860|ref|NP_645948.1| FmhC protein [Staphylococcus aureus
subsp. aureus MW2]
gi|3767594|dbj|BAA33857.1| Eprh [Staphylococcus aureus]
gi|21204299|dbj|BAB94996.1| FmhC protein [Staphylococcus aureus
subsp. aureus MW2]
Length = 414
Score = 121 bits (304), Expect = 2e-26
Identities = 109/417 (26%), Positives = 193/417 (46%), Gaps = 13/417 (3%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M L+ +EF +Y+ + + + Q+ E+ K ++ +G + D I + + T
Sbjct: 1 MKFSTLSEEEFTNYTKKH-FKHYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTE 59
Query: 61 PMTGGLHMEVNS--GPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+ S GP + ++K + +F+KEL + + +L+ PY G
Sbjct: 60 ARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANG 119
Query: 117 K-PKGAPNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ K N+ ++ L IGY H G GY + W V +L+ LLK + R
Sbjct: 120 RIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTR 179
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
+KK + G+K+ L EE + F + ++ + + DY++ + + DKA I
Sbjct: 180 RNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKI 239
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +N EY L++ K+E ++ ++ N +S K + +L QL+S++ R +
Sbjct: 240 ACINLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKT 299
Query: 295 EPFIQKFGNQDVV-LAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
E I F + V+ LA +LFI + E YL SGS ++N++ LQ ++++ A
Sbjct: 300 EELI--FEDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNI 357
Query: 354 TFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI G F GV +FK+ FN ++ +G F P+ YK +L+ K+
Sbjct: 358 NRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV 414
>gi|4574238|gb|AAD23963.1|AF106851_2 FmhC [Staphylococcus aureus]
Length = 414
Score = 121 bits (303), Expect = 2e-26
Identities = 107/416 (25%), Positives = 192/416 (45%), Gaps = 11/416 (2%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M L+ +EF +Y+ + + + Q+ E+ K ++ +G + D I + + T
Sbjct: 1 MKFSTLSEEEFTNYTKKH-FKHYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTE 59
Query: 61 PMTGGLHMEVNS--GPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+ S GP + ++K + +F+KEL + + +L+ PY G
Sbjct: 60 ARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANG 119
Query: 117 K-PKGAPNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ K N+ ++ L IGY H G GY + W V +L+ LLK + R
Sbjct: 120 RIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTR 179
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
+KK + G+K+ L EE + F + ++ + + DY++ + + DKA I
Sbjct: 180 RNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKI 239
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
A +N EY L++ K+E ++ ++ N +S + + +L QL+S++ R +
Sbjct: 240 ACINLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKRNKSKLNQLNMQLSSINNRISKT 299
Query: 295 EPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQST 354
E I + G + LA +LFI + E YL SGS ++N++ LQ ++++ A
Sbjct: 300 EELILEDGPV-LDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNIN 358
Query: 355 FYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKI 407
YNF GI G F GV +FK+ FN ++ +G F P+ YK +L+ K+
Sbjct: 359 RYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV 414
>gi|21284062|ref|NP_647150.1| fmhA protein [Staphylococcus aureus
subsp. aureus MW2]
gi|21205505|dbj|BAB96198.1| fmhA protein [Staphylococcus aureus
subsp. aureus MW2]
Length = 416
Score = 120 bits (302), Expect = 3e-26
Identities = 105/405 (25%), Positives = 184/405 (44%), Gaps = 15/405 (3%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTGG 65
LT+ EF +++ + + +G D+ +G + D I + T T
Sbjct: 6 LTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKG-DVHLVGVKDDNGQVIAGCLLTEARTLK 64
Query: 66 L--HMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGK-PKG 120
+ + GP ++N + F+K L +Y K L +L+ PY +G+ K
Sbjct: 65 FFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGEIVKS 124
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKK 179
N + + +GY H G +GY + W V +L+ T LLK + R +KK
Sbjct: 125 YDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKK 184
Query: 180 AMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNF 239
G+K + L +E F D+ ++ + + L Y+++ + D A +A ++
Sbjct: 185 TYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDL 244
Query: 240 REYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQ 299
EY LQL ++L +++ ++ + + +S K +RT+L QL S +++++ I+
Sbjct: 245 NEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNS---NKRKIDNTIE 301
Query: 300 KFGNQDVV--LAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYN 357
+ V LA +LFIY+ E YL SGS ++N + LQ +++ A YN
Sbjct: 302 QIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYN 361
Query: 358 FLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYK 399
F GI G+F S GV +FK+ FN ++ +G F PL YK
Sbjct: 362 FYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYK 406
>gi|10440955|gb|AAG16879.1| lysostaphin endopeptidase resistance
[Staphylococcus sciuri]
Length = 415
Score = 119 bits (299), Expect = 8e-26
Identities = 87/319 (27%), Positives = 160/319 (49%), Gaps = 6/319 (1%)
Query: 76 HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKP-KGAPNTYLIDDLTSIG 134
++N + + F+K L Y K Q L +L+ PY Q+ T +GK + + L S+G
Sbjct: 79 YNNKELVNFFFKNLTKYLKKQNCLFVLVDPYIVIQKHTADGKTIESYEHQSFKAILESLG 138
Query: 135 YHHDGLHIGY-PGGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKAMSFGIKIRVLKRE 193
Y H G +GY P + W V +L+ + LLK + + R +KK ++I L
Sbjct: 139 YKHQGYSVGYQPMSQIRWLSVLDLKDKSEDELLKEMNYQTRRNIKKTEEMNVQIEDLNIN 198
Query: 194 ELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYDHNLQLNAKKL 253
E F + ++ + + LDY+++ + D + IA +N ++Y +L+L ++L
Sbjct: 199 ETERFFKLFKMAEEKHGFSFRGLDYFKEMQKIYHDNSMLKIAPINLKDYLKSLELQDEQL 258
Query: 254 EEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQKFGNQDVVLAGSLF 313
+ + + +N+ + N +S K L+ +L S +K+ +++ I+ G + + LA +L+
Sbjct: 259 KNDVLLAENKLKENPNSKKQKTAINNLLQRLDSSNKKIDKIKRLIETDG-EIIDLAAALY 317
Query: 314 IYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLGIQGNFDGSD---G 370
IY+ E YL SGS ++N+F LQ +++ + YNF G+ G+F + G
Sbjct: 318 IYNNHEMYYLSSGSNPKYNEFMGAYKLQWEMIKFSKTHNIERYNFYGVTGDFSDTAEDYG 377
Query: 371 VLRFKQNFNGYIVRKMGTF 389
V +FK+ FN + +G F
Sbjct: 378 VQQFKKGFNANVEEYIGDF 396
>gi|15925401|ref|NP_372935.1| fmhA protein [Staphylococcus aureus
subsp. aureus Mu50]
gi|15927989|ref|NP_375522.1| fmhA protein [Staphylococcus aureus
subsp. aureus N315]
gi|25320223|pir||D90042 fmhA protein [imported] - Staphylococcus
aureus (strain N315)
gi|4574233|gb|AAD23960.1|AF106849_1 FmhA [Staphylococcus aureus]
gi|13702360|dbj|BAB43501.1| fmhA protein [Staphylococcus aureus
subsp. aureus N315]
gi|14248185|dbj|BAB58573.1| fmhA protein [Staphylococcus aureus
subsp. aureus Mu50]
Length = 416
Score = 119 bits (299), Expect = 8e-26
Identities = 104/405 (25%), Positives = 184/405 (44%), Gaps = 15/405 (3%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTGG 65
LT+ EF +++ + + +G D+ +G + D I + T T
Sbjct: 6 LTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKG-DVHLVGVKDDNGQVIAGCLLTEARTLK 64
Query: 66 L--HMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGK-PKG 120
+ + GP ++N + F+K L +Y K L +L+ PY +G+ K
Sbjct: 65 FFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGEIVKS 124
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKK 179
N + + +GY H G +GY + W V +L+ T LLK + R +KK
Sbjct: 125 YDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKK 184
Query: 180 AMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNF 239
G+K + L +E F D+ ++ + + L Y+++ + D A +A ++
Sbjct: 185 TYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDL 244
Query: 240 REYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQ 299
EY LQL ++L +++ ++ + + +S K +RT+L QL S +++++ I+
Sbjct: 245 NEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNS---NKRKIDNTIE 301
Query: 300 KFGNQDVV--LAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYN 357
+ V LA +LFIY+ E YL SGS ++N + LQ +++ A YN
Sbjct: 302 QIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYN 361
Query: 358 FLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYK 399
F GI G++ S GV +FK+ FN ++ +G F PL YK
Sbjct: 362 FYGITGDYSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYK 406
>gi|27468907|ref|NP_765544.1| fmhA protein [Staphylococcus
epidermidis ATCC 12228]
gi|27316455|gb|AAO05630.1|AE016750_235 fmhA protein [Staphylococcus
epidermidis ATCC 12228]
Length = 415
Score = 114 bits (286), Expect = 2e-24
Identities = 106/415 (25%), Positives = 192/415 (45%), Gaps = 13/415 (3%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTI 60
M LT++EFE ++ + + Q+ K D+ +G + D + I + + T
Sbjct: 1 MKFVNLTSEEFEQFTSE-NFSHYTQSSIHYNNRSKTKGDVHLVGVKDDQEDVIAACLLTE 59
Query: 61 PMTGGL--HMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPY--DTYQEFTG 114
+ + + GP +N ++ F+K L Y K L +L+ PY + ++ G
Sbjct: 60 ARSLKFFKYFYTHRGPVMNFNNLVLVRFFFKSLTAYLKKHNCLYVLVDPYVLENLRQPNG 119
Query: 115 EGKPKGAPNTYLIDDLTSIGYHHDGLHIGYPG-GEPDWHYVKNLEGITPQNLLKSFSKKG 173
E + N LI + +GY H G +GY + W V NL+ + LLK +
Sbjct: 120 E-IIESFDNRALIKTMEELGYKHQGYTVGYDTMSQIRWLSVLNLKDKSEDQLLKEMDYQT 178
Query: 174 RPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFV 233
R +KK G+K++ L E+ F ++ ++ + + Y+ + ++ D A
Sbjct: 179 RRNIKKTYEMGVKVKTLPIEKTDTFFELFKMAEEKHGFKFREEPYFVEMQKTYEDHAMLK 238
Query: 234 IATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKE 293
+A ++ ++Y LQ + L +Q+ ++ + N +S K + T++ Q S ++ ++
Sbjct: 239 LAYIDLQDYLDTLQTKHQNLNQQLKDVEKTLEENPNSKKNKTKHTQVKQQFDSNARKIRQ 298
Query: 294 VEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
+ I + G Q + LA +L+IY+ E YL SGS ++N + LQ ++Q A +
Sbjct: 299 TKEKIAEEG-QVLHLAAALYIYNDHEVYYLSSGSNPKYNAYMGAYRLQWDMIQFAKEHNI 357
Query: 354 TFYNFLGIQGNFDGS---DGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLK 405
YNF G+ G+F + GV +FK+ FN I +G F PL YK Q L+
Sbjct: 358 DRYNFYGVTGDFSENAEDAGVQKFKEGFNAKIYEYIGDFIKPIKPLFYKVKQELE 412
>gi|2257458|dbj|BAA21486.1| epr [Staphylococcus capitis]
Length = 413
Score = 100 bits (248), Expect = 6e-20
Identities = 89/334 (26%), Positives = 150/334 (44%), Gaps = 6/334 (1%)
Query: 78 NSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKP-KGAPNTYLIDDLTSIGYH 136
N + ++ FYK L Y K L +L PY +G+ N LI L +IGY
Sbjct: 81 NFELVRFFYKNLTRYLKKNRGLFVLTDPYTLENIRNAQGEILTSYDNRPLIKTLKNIGYK 140
Query: 137 HDGLHIGYP-GGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKAMSFGIKIRVLKREEL 195
H G IGY + W V +L LL + R +KK +++R L EE
Sbjct: 141 HQGYSIGYSQTSQIRWLSVLDLNNKNTDMLLSEMDYQTRRNIKKTYEMNVQVRTLSIEET 200
Query: 196 HIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYDHNLQLNAKKLEE 255
F + ++ + ++ DY++ + D + +A +N + +L +
Sbjct: 201 SRFFKLFKMAEEKHGFKFRNQDYFEKMQKIYNDNSMLKLAYINLSDLLEKQNNKITQLNK 260
Query: 256 QITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQKFGNQDVVLAGSLFIY 315
Q + N + N +S K + ++ Q+++ +++ E + I+ G + + LA + +IY
Sbjct: 261 QYEEIINALKANPNSKKNKNKANQINQQISAQNRKINETKELIKTDG-KIIDLAAAFYIY 319
Query: 316 SPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLGIQGNFDGSD---GVL 372
+ E YL SGS ++N + LQ +++ A + YNF GI G+F + GV
Sbjct: 320 NNDEVYYLSSGSNPKYNAYMGAYRLQWEMIKFAKQNNIPRYNFYGITGDFSETAEDYGVQ 379
Query: 373 RFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKK 406
RFK+ FN Y+ +G F P YK LLK+
Sbjct: 380 RFKEGFNAYVEEYIGDFIKPLRPFIYKIYTLLKR 413
>gi|2072412|gb|AAB53784.1| lysostaphin immunity factor
[Staphylococcus simulans]
Length = 413
Score = 99.8 bits (247), Expect = 7e-20
Identities = 89/330 (26%), Positives = 149/330 (44%), Gaps = 6/330 (1%)
Query: 82 LKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKP-KGAPNTYLIDDLTSIGYHHDGL 140
++ FY+ L Y K Q L +L PY + +G+ + N ++ + +GY H G
Sbjct: 85 VRFFYENLTTYLKKQNCLYVLTDPYLLENIRSCDGEILESYDNETFMNVMNLLGYRHQGF 144
Query: 141 HIGYP-GGEPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKAMSFGIKIRVLKREELHIFK 199
GY + W V NLE + LLK + R +KK +K+R L E F
Sbjct: 145 TTGYSQTSQIRWLSVLNLENKDEKQLLKEMDYQTRRNIKKTYEMQVKVRDLSINETDRFF 204
Query: 200 DITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYDHNLQLNAKKLEEQITV 259
+ ++ + + Y++ ++ D + +A ++ E +L I
Sbjct: 205 KLFKMAEEKHGFKFREQSYFERMQKTYADNSMLKLAYIDLEELLETQNAKVAELNTDIEN 264
Query: 260 LDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQKFGNQDVVLAGSLFIYSPKE 319
+ + N +S K + + QLA+ +++ E + I+ G + LA + +IY+P E
Sbjct: 265 IQAALKENPNSKKNKNKYAQYQKQLAAQERKITETKKLIETDGPV-LDLAAAYYIYTPHE 323
Query: 320 TVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLGIQGNF--DGSD-GVLRFKQ 376
YL SGS ++N + LQ ++Q A + YNF GI G+F D D GV +FK+
Sbjct: 324 VYYLSSGSNPKYNAYMGAYRLQWEMIQFAKNKGINRYNFYGITGDFSEDAEDFGVQKFKE 383
Query: 377 NFNGYIVRKMGTFRYYPNPLKYKSIQLLKK 406
FN ++ +G F PL YK QLL +
Sbjct: 384 GFNAHVEEYVGDFIKPIKPLFYKIHQLLNR 413
>gi|29377142|ref|NP_816296.1| FemAB family protein [Enterococcus
faecalis V583]
gi|29344608|gb|AAO82366.1| FemAB family protein [Enterococcus
faecalis V583]
Length = 401
Score = 87.0 bits (214), Expect = 5e-16
Identities = 95/410 (23%), Positives = 187/410 (45%), Gaps = 23/410 (5%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTGG 65
+ A+ +++ N+ L + +Q+ AK+ G +I +G + S+V P+ G
Sbjct: 8 IPAEVHDTFVKNHPLCNLLQSSSWAKVKDNWGSEI--VGVYEKDTLVASSLVLIKPLPAG 65
Query: 66 LHM-EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEF-TGEGKPKGA 121
M GP ++N + + +F EL+ + K + AL + + P YQ+F GE A
Sbjct: 66 FTMLYTPRGPVMDYTNERLVSYFMAELKKFGKKKRALFIKMDPAVHYQDFHLGEEHQPHA 125
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
T +I+ L G + GL + +P + E + + L KS K ++K A
Sbjct: 126 EATSIIETLKEAGAKYQGLTMDMGATIQPRFQANIYREDFSEEQLSKSTKK----MIKTA 181
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
G+ ++ + + F+ + ST +R+ ++ DY++ + + + + ++A +N +
Sbjct: 182 EKKGVVVQQGHVDFVDEFEKVIQSTMERQHISLRNSDYFKKLLNIYPEDSFIMLAQVNLK 241
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQK 300
E L ++ ++ L N +N ++R L ASL + KE+E I +
Sbjct: 242 E---RLDSTRQRYDKNQKDLSNLKENQV------KKRHNLEELDASLTRELKELEENIAE 292
Query: 301 FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLG 360
G + V +AG+L + + L++G + ++ V +QE R N G
Sbjct: 293 AG-EIVTVAGALAVTFGPTSEILYAGLDDRYKRYMPTYVTWRDAIQECFNRGCESCNMGG 351
Query: 361 IQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
++G+ + DG+++FK NFN I +G F N L +K+ + K+ ++
Sbjct: 352 LEGSLN--DGLIKFKANFNPTINEFIGEFDLPVNKLLFKASEYAYKLRKQ 399
>gi|15675170|ref|NP_269344.1| putative antimicrobial resistance
factor [Streptococcus pyogenes]
gi|13622333|gb|AAK34065.1| putative antimicrobial resistance factor
[Streptococcus pyogenes M1 GAS]
Length = 407
Score = 86.7 bits (213), Expect = 6e-16
Identities = 101/397 (25%), Positives = 187/397 (46%), Gaps = 25/397 (6%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
++ +E +S+ + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
Query: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFT-GEGKPKGA 121
+ + GP + + + K L++Y K++ AL + P +++ G+ + +
Sbjct: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
I +L G H GL + +P + N+ T +NL F K R L+K A
Sbjct: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRRLIKDA 185
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
G+K + + ELH F I S T R++ ++ Y+Q ++GDKA +A +N
Sbjct: 186 KQRGVKTYRVSQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI- 244
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKEVEPFIQ 299
+KL++ L +Q+ T + + ++R +L +Q ASL++ E E F
Sbjct: 245 ---------PQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTD 295
Query: 300 KFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFL 359
++ ++VV+AG L I L++G +F KFY +L V Q+A + + N
Sbjct: 296 QY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPNVFQDAYQDGIIWANMG 354
Query: 360 GIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 355 GVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
>gi|19746137|ref|NP_607273.1| putative antimicrobial resistance
factor [Streptococcus pyogenes MGAS8232]
gi|19748313|gb|AAL97772.1| putative antimicrobial resistance factor
[Streptococcus pyogenes MGAS8232]
Length = 407
Score = 84.7 bits (208), Expect = 2e-15
Identities = 100/397 (25%), Positives = 186/397 (46%), Gaps = 25/397 (6%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
++ +E +S+ + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 12 ISEEEHDSFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
Query: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFT-GEGKPKGA 121
+ + GP + + + K L++Y K++ AL + P +++ G+ + +
Sbjct: 70 RSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKTKKALFIKYDPAILLKQYALGQEEEEKP 129
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
I +L G H GL + +P + N+ T +NL F K R L+K A
Sbjct: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRRLIKDA 185
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
G++ + ELH F I S T R++ ++ Y+Q ++GDKA +A +N
Sbjct: 186 KQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI- 244
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKEVEPFIQ 299
+KL++ L +Q+ T + + ++R +L +Q ASL++ E E F
Sbjct: 245 ---------PQKLDQYRQQLILINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTD 295
Query: 300 KFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFL 359
++ ++VV+AG L I L++G +F KFY +L V Q+A + + N
Sbjct: 296 QY-PEEVVVAGILSISYGNVMEMLYAGMNNDFKKFYPQYLLYPNVFQDAYQDGIIWANMG 354
Query: 360 GIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 355 GVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
>gi|21910382|ref|NP_664650.1| putative antimicrobial resistance
factor [Streptococcus pyogenes MGAS315]
gi|28895958|ref|NP_802308.1| putative antimicrobial resistance
factor [Streptococcus pyogenes SSI-1]
gi|21904579|gb|AAM79453.1| putative antimicrobial resistance factor
[Streptococcus pyogenes MGAS315]
gi|28811208|dbj|BAC64141.1| putative antimicrobial resistance
factor [Streptococcus pyogenes SSI-1]
Length = 407
Score = 83.2 bits (204), Expect = 8e-15
Identities = 99/397 (24%), Positives = 186/397 (45%), Gaps = 25/397 (6%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
++ +E + + + S +Q + AK+ K + +G Y+ + ++ +S++ + G
Sbjct: 12 ISEEEHDFFVKEHQQISVLQGSDWAKI--KNQWQNERIGIYKEEKQVASLSLLIKLLPLG 69
Query: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFT-GEGKPKGA 121
+ + GP + + + K L++Y K++ AL + P +++ G+ + +
Sbjct: 70 RSIIYIPRGPVMDYLDRDLVVFTMKTLKDYGKTKKALFIKYDPAILLKQYAPGQEEEEKP 129
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
I +L G H GL + +P + N+ T +NL F K R L+K A
Sbjct: 130 LALAAIKNLQEAGVHWTGLTMEIADSIQP--RFQANI--YTQENLEMQFPKHTRRLIKDA 185
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
G++ + ELH F I S T R++ ++ Y+Q ++GDKA +A +N
Sbjct: 186 KQRGVETYRASQSELHKFSKIVSLTEKRKNISLRNEAYFQKLMTTYGDKAYLHLAKVNI- 244
Query: 241 EYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKEVEPFIQ 299
+KL++ L+ +Q+ T + + ++R +L +Q ASL++ E E F
Sbjct: 245 ---------PQKLDQYRQQLNLINQDITRTQAHQKKRLKKLEDQKASLERYITEFEGFTD 295
Query: 300 KFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFL 359
++ ++VV+AG L I L++G +F KFY +L V Q+A + + N
Sbjct: 296 QY-PEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYLLYPKVFQDAYQDGIIWANMG 354
Query: 360 GIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
G++G+ D DG+ +FK NF I +G F +PL
Sbjct: 355 GVEGSLD--DGLTKFKANFAPTIEEFIGEFNLPVSPL 389
>gi|21283909|ref|NP_646997.1| FmhB protein [Staphylococcus aureus
subsp. aureus MW2]
gi|21205351|dbj|BAB96045.1| FmhB protein [Staphylococcus aureus
subsp. aureus MW2]
Length = 421
Score = 80.5 bits (197), Expect = 6e-14
Identities = 88/426 (20%), Positives = 187/426 (43%), Gaps = 33/426 (7%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVY 58
M +T +E +++ ++ +Q + A+ K G+ + DG+++ ++ +
Sbjct: 1 MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFK 60
Query: 59 TIPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P ++ G +SN + L + AK++ A + I P +
Sbjct: 61 KVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDK----- 115
Query: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVK-NLEGITP-----QNLLKSFS 170
T + +L ++G+ H G G Y++ + ITP LL SF
Sbjct: 116 ------GTDALQNLKALGFKHKGFKEGLSK-----DYIQPRMTMITPIDKNDDELLNSFE 164
Query: 171 KKGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGD-- 228
++ R V+ A+ G + RE L F ++ T +R ++ + + Y+++ YD+ +
Sbjct: 165 RRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDG 224
Query: 229 KAEFVIATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASL 287
AE + L+ +E + +L +I + + + AK + + N++A
Sbjct: 225 DAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKN 284
Query: 288 DKRRKEVEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQE 347
+ ++++E ++K + + L+G+L +++ ++ YL+ S EF F +Q +M+
Sbjct: 285 EDLKRDLEA-LEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKY 343
Query: 348 ALKRQSTFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLL 404
A + +T Y+F G + D G+ FK+ + Y+ K+G F Y N Y+ I+ +
Sbjct: 344 AREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQV 403
Query: 405 KKILRR 410
K L +
Sbjct: 404 KPRLTK 409
>gi|15925252|ref|NP_372786.1| FmhB protein [Staphylococcus aureus
subsp. aureus Mu50]
gi|15927842|ref|NP_375375.1| FmhB protein [Staphylococcus aureus
subsp. aureus N315]
gi|25506053|pir||A99924 FmhB protein [imported] - Staphylococcus
aureus (strain N315)
gi|4574235|gb|AAD23961.1|AF106850_1 FmhB [Staphylococcus aureus]
gi|13702062|dbj|BAB43354.1| FmhB protein [Staphylococcus aureus
subsp. aureus N315]
gi|14248035|dbj|BAB58424.1| FmhB protein [Staphylococcus aureus
subsp. aureus Mu50]
Length = 421
Score = 80.1 bits (196), Expect = 6e-14
Identities = 88/426 (20%), Positives = 187/426 (43%), Gaps = 33/426 (7%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVY 58
M +T +E +++ ++ +Q + A+ K G+ + DG+++ ++ +
Sbjct: 1 MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFK 60
Query: 59 TIPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P ++ G +SN + L + AK++ A + I P +
Sbjct: 61 KVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDK----- 115
Query: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVK-NLEGITP-----QNLLKSFS 170
T + +L ++G+ H G G Y++ + ITP LL SF
Sbjct: 116 ------GTDALQNLKALGFKHKGFKEGLSK-----DYIQPRMTMITPIDKNDDELLNSFE 164
Query: 171 KKGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGD-- 228
++ R V+ A+ G + RE L F ++ T +R ++ + + Y+++ YD+ +
Sbjct: 165 RRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDG 224
Query: 229 KAEFVIATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASL 287
AE + L+ +E + +L +I + + + AK + + N++A
Sbjct: 225 DAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKN 284
Query: 288 DKRRKEVEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQE 347
+ ++++E ++K + + L+G+L +++ ++ YL+ S EF F +Q +M+
Sbjct: 285 EDLKRDLEA-LEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKY 343
Query: 348 ALKRQSTFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLL 404
A + +T Y+F G + D G+ FK+ + Y+ K+G F Y N Y+ I+ +
Sbjct: 344 AREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQLIEQV 403
Query: 405 KKILRR 410
K L +
Sbjct: 404 KPRLTK 409
>gi|21431652|gb|AAF14182.2|AF105976_1 FmhB [Staphylococcus aureus]
Length = 421
Score = 78.2 bits (191), Expect = 2e-13
Identities = 87/426 (20%), Positives = 186/426 (43%), Gaps = 33/426 (7%)
Query: 1 MALKELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVY 58
M +T +E +++ ++ +Q + A+ K G+ + DG+++ ++ +
Sbjct: 1 MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFK 60
Query: 59 TIPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEG 116
+P ++ G +SN + L + AK++ + I P +
Sbjct: 61 KVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKTYAIKIDPDVEVDK----- 115
Query: 117 KPKGAPNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVK-NLEGITP-----QNLLKSFS 170
T + +L ++G+ H G G Y++ + ITP LL SF
Sbjct: 116 ------GTDALQNLKALGFKHKGFKEGLSK-----DYIQPRMTMITPIDKNDDELLNSFE 164
Query: 171 KKGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGD-- 228
++ R V+ A+ G + RE L F ++ T +R ++ + + Y+++ YD+ +
Sbjct: 165 RRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDG 224
Query: 229 KAEFVIATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASL 287
AE + L+ +E + +L +I + + + AK + + N++A
Sbjct: 225 DAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKN 284
Query: 288 DKRRKEVEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQE 347
+ ++++E ++K + + L+G+L +++ ++ YL+ S EF F +Q +M+
Sbjct: 285 EDLKRDLEA-LEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKY 343
Query: 348 ALKRQSTFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLL 404
A + +T Y+F G + D G+ FK+ + Y+ K+G F Y N Y+ I+ +
Sbjct: 344 AREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQV 403
Query: 405 KKILRR 410
K L +
Sbjct: 404 KPRLTK 409
>gi|22536689|ref|NP_687540.1| murM protein, putative [Streptococcus
agalactiae 2603V/R]
gi|25010625|ref|NP_735020.1| Unknown [Streptococcus agalactiae
NEM316]
gi|22533530|gb|AAM99412.1|AE014215_6 murM protein, putative
[Streptococcus agalactiae 2603V/R]
gi|23094979|emb|CAD46200.1| Unknown [Streptococcus agalactiae
NEM316]
Length = 406
Score = 77.4 bits (189), Expect = 5e-13
Identities = 93/417 (22%), Positives = 189/417 (45%), Gaps = 35/417 (8%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVYTIPMT 63
++ KE+++++ + + + + A++ K + +G+ D ++ ++ ++ ++P+
Sbjct: 8 ISEKEYDAFAIASSQTNLLHSSKWAQV--KSNWQNERLGFYKDDQLVAVASILIKSLPL- 64
Query: 64 GGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGAL------ELLIKPYDTYQEFTGE 115
G + + GP +SN + + K L+N+ + + A+ LL++ Y +E E
Sbjct: 65 GFTMLYIPRGPIMDYSNKELVNFVLKTLKNFGRKKRAVFAKFDPALLLRQYHLKEENVAE 124
Query: 116 GKPKGAPNTYLIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGR 174
+ + ID+L S G G +P + N+ T N+ ++F K +
Sbjct: 125 EIDE---SRQAIDNLKSAGAQWIGPTKAISETIQP--RFQANI--YTKANIEENFPKHTK 177
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
L+K A G++I ++L F + + T +R+ ++ +Y+ +G+ A +
Sbjct: 178 RLIKDAKHRGVQIYRANIDDLPKFATVVALTENRKGVALRNENYFHQLMTIYGEDAYLYL 237
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQR-TELVNQLASLDKRRKE 293
A +N K+L + L ++ +++ + + R T L Q AS+ + E
Sbjct: 238 AKVNL----------PKRLAQFKEQLLQIQKDLSETPSHQKSRLTRLNQQEASVKQYILE 287
Query: 294 VEPFIQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
+ F +K+ ++ V+ AG L I L++G F KFY +L V ++A K
Sbjct: 288 FQEFSKKYPDEPVI-AGILSIRFGNVLEMLYAGMDDSFRKFYPQYLLNARVFEDAFKNDI 346
Query: 354 TFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
N G++G+ + DG+ +FK NFN +G F NPL YK L I ++
Sbjct: 347 VSANLGGVEGSLN--DGLTKFKSNFNPMFEEYIGEFNLAINPLLYKLANLAYTIRKK 401
>gi|27468753|ref|NP_765390.1| FmhB protein [Staphylococcus
epidermidis ATCC 12228]
gi|27316301|gb|AAO05476.1|AE016750_81 FmhB protein [Staphylococcus
epidermidis ATCC 12228]
Length = 416
Score = 75.1 bits (183), Expect = 2e-12
Identities = 67/301 (22%), Positives = 138/301 (45%), Gaps = 33/301 (10%)
Query: 127 IDDLTSIGYHHDGLHIGYPGG--EPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKAMSFG 184
+ +L +G+ H G G +P + ++ T L++SF ++ R V+ A+ G
Sbjct: 120 LKNLRELGFKHKGFKEGLSKDYIQPRMTMITPIDK-TDDELVQSFERRNRSKVRLALKRG 178
Query: 185 IKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYDH 244
K+ RE L IF ++ T +R ++ + + Y+++ YD+ + D
Sbjct: 179 TKVERSNREGLKIFANLMKITGERDGFLTRDISYFENIYDALHE--------------DG 224
Query: 245 NLQLNAKKLEEQITVLDNRHQN------NTDSAKYHRQRTELVNQLASLDKRRKEVEPF- 297
+ +L KLE + VLD +Q+ + + +Q + +N+L +D + K+
Sbjct: 225 DAELFLVKLEPK-PVLDTVNQDLEAQLAEKEKLQSKKQDKKTLNKLNDIDNKIKKTNELK 283
Query: 298 -----IQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQ 352
++K + + L+G+L +++ ++ YL+ S ++ F +Q +M+ A +
Sbjct: 284 SDLTELEKSEPEGIYLSGALLMFAGNKSYYLYGASSNDYRDFLPNHHMQFEMMKYAREHG 343
Query: 353 STFYNFLGIQGNFDGSD---GVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQLLKKILR 409
+T Y+F G + D G+ FK+ + Y+ K+G F Y N Y ++ +K L
Sbjct: 344 ATTYDFGGTDNDPDKDSEHYGLWAFKRVWGTYLSEKIGEFDYVLNQPLYHLVEKVKPRLT 403
Query: 410 R 410
+
Sbjct: 404 K 404
>gi|24379185|ref|NP_721140.1| putative peptidoglycan branched
peptide synthesis protein MurM [Streptococcus mutans
UA159]
gi|24377094|gb|AAN58446.1|AE014914_8 putative peptidoglycan
branched peptide synthesis protein MurM [Streptococcus
mutans UA159]
Length = 404
Score = 74.3 bits (181), Expect = 3e-12
Identities = 91/397 (22%), Positives = 168/397 (41%), Gaps = 24/397 (6%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTGG 65
++ +E +++ N + +Q+ AK+ K ++ +G+ D K+ + + P+ G
Sbjct: 8 ISKEEHDNFIKNSSQTNLLQSSSWAKV--KDEWENERIGFYQDSKLVASASILIRPLPLG 65
Query: 66 LHM-EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGAP 122
+ M + GP + + + L+ +AK + AL + P+ + + P
Sbjct: 66 MTMFYIPRGPVMNYQDKDLVNFVLTSLKKFAKRKRALFIKFDPFILLNHHQIDEEAINNP 125
Query: 123 NTY-LIDDLTSIGYHHDGLHIGYPGG-EPDWHYVKNLEGITPQNLLKSFSKKGRPLVKKA 180
+ID L +G G +P + EG + NL SKK R ++ A
Sbjct: 126 QAQTIIDTLKHLGCEWLGQTSDMGETIQPRFQANIYAEGFSEANL----SKKIRQSIRTA 181
Query: 181 MSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFR 240
+ G+ IR E L F D+ T DR+ + +DYY+ D++ + +A+LN +
Sbjct: 182 KNKGVSIRFGGYELLADFSDLMKKTEDRKSIHLRGIDYYRKLLDNYPQHSFITLASLNLK 241
Query: 241 EYDHNLQLNAKKLEEQITVL-DNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQ 299
E L+ KK + + DN + D+ K +R L +++A L + +
Sbjct: 242 ERLTELESQRKKAQNNLAKFGDNVKPSKIDNTKKEIER--LSDEIAFLQEHLSQ------ 293
Query: 300 KFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFL 359
G V L+G+L + K + +++G EF ++ A A +R S + N
Sbjct: 294 --GKDTVPLSGTLSLEFGKTSENVYAGMDDEFRRYQAAIYTWFATANHAFERGSHWQNMG 351
Query: 360 GIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPL 396
GI+ + G G+ FK F I +G F +PL
Sbjct: 352 GIENDLSG--GLYNFKSKFKPEIEEFIGEFNLPVSPL 386
>gi|12746261|gb|AAK07418.1| MurM [Streptococcus pneumoniae]
Length = 406
Score = 73.9 bits (180), Expect = 4e-12
Identities = 94/420 (22%), Positives = 189/420 (44%), Gaps = 40/420 (9%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTGG 65
+ A E++ + +++L + +Q+ K+ K ++ +G +GK+ ++ + + G
Sbjct: 8 IPALEYDQFVKDHELANVLQSSAWEKV--KSDWNHERLGVYEEGKLLAVASILIKSLPLG 65
Query: 66 LHM-EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEFTGEGKPKGA 121
M + GP + +++ LK + +++YA+S+ A+ + P Q + K +
Sbjct: 66 YKMFYIPRGPILDYRDAELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKTEYP 125
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQNLLK-SFSKKGRPLVKK 179
N L++ L +G G E D ++ I +N + SK R ++
Sbjct: 126 ENLALVETLGQLGVKWSG-----QTAEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRT 180
Query: 180 AMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNF 239
A + G++I+ E L F + T R++ ++ YY+ D+F DKA +ATL+
Sbjct: 181 ARNKGVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDV 240
Query: 240 REYDHNLQLNAKKLEEQIT---VLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEP 296
+ +++LEEQ+ L+ +T ++K Q+ E +D
Sbjct: 241 SK-------RSQELEEQLAKNRALEETFTESTRTSKVEAQKKEKERLEEEID-------- 285
Query: 297 FIQKF---GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQS 353
F+Q + G ++ LA +L + +V L++G +F ++ AP + A +R
Sbjct: 286 FLQGYMNMGKSNIPLAATLSLEFGTTSVNLYAGMDDDFKRYNAPILTWYETACYAFERGM 345
Query: 354 TFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKILRR 410
+ N G++ + +G G+ FK+ FN I +G F +PL Y ++L +K LR+
Sbjct: 346 LWQNLGGVENSLNG--GLYHFKEKFNPTIEEYLGEFTMPTHPL-YPLLRLALDFRKTLRK 402
>gi|23037888|ref|ZP_00070084.1| hypothetical protein [Oenococcus
oeni MCW]
Length = 92
Score = 72.8 bits (177), Expect = 1e-11
Identities = 38/89 (42%), Positives = 53/89 (58%)
Query: 322 YLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLGIQGNFDGSDGVLRFKQNFNGY 381
Y+FS + EF FY P Q +++ ALK + YNF G+ G+ G DGV FK+ F GY
Sbjct: 3 YMFSYTNAEFKNFYGPYRTQADMLEFALKEKVPVYNFYGVSGDRSGHDGVYEFKKGFQGY 62
Query: 382 IVRKMGTFRYYPNPLKYKSIQLLKKILRR 410
+V MG F N +Y+ +Q +KKI+RR
Sbjct: 63 MVDNMGAFILPINKFRYQFLQTIKKIIRR 91
>gi|11385674|gb|AAG34918.1|AF281137_1 MurM [Streptococcus
pneumoniae]
Length = 406
Score = 72.8 bits (177), Expect = 1e-11
Identities = 95/417 (22%), Positives = 187/417 (44%), Gaps = 42/417 (10%)
Query: 10 EFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTGGLHM- 68
E++ + ++L + +Q+ K+ K ++ G +GK+ ++ + + G M
Sbjct: 12 EYDQFVKEHELANVLQSSAWEKV--KSDWNHEKFGVYEEGKLLAVASILIKSLPLGYKMF 69
Query: 69 EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEFTGEGKPKGAPNTY 125
+ GP + + + LK + +++YA+S+ A+ + P Q + K + N
Sbjct: 70 YIPRGPILDYRDIELLKFVLQSIKSYARSKRAIFVTFDPSICLSQSLINQEKIEYPENLA 129
Query: 126 LIDDLTSIGYHHDGL--HIGYPGGEPDWHYVKNLEGITPQNLLK-SFSKKGRPLVKKAMS 182
+ID L +G G +G D + I +N + SK R ++ A +
Sbjct: 130 IIDSLQQMGVRWSGKTEEMG------DTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARN 183
Query: 183 FGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREY 242
G++I+ E L F ++ T R++ ++ YY+ D+F DKA +ATL+ +
Sbjct: 184 KGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSK- 242
Query: 243 DHNLQLNAKKLEEQIT---VLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQ 299
+++LEEQ+ L+ +T ++K Q+ E +R E F+Q
Sbjct: 243 ------RSQELEEQLAKNRALEETFTESTRTSKVEAQKKE--------KERLLEELTFLQ 288
Query: 300 KF---GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFY 356
++ G V LA +L + +V +++G +F ++ AP + + A +R +
Sbjct: 289 EYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYETARYAFERGMVWQ 348
Query: 357 NFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKILRR 410
N G++ + +G G+ FK+ FN I +G F +PL Y ++L +K LR+
Sbjct: 349 NLGGVENSLNG--GLYHFKEKFNPTIEEYLGEFTMPTHPL-YPLLRLALDFRKTLRK 402
>gi|11385680|gb|AAG34921.1|AF281140_1 MurM [Streptococcus
pneumoniae]
Length = 406
Score = 72.4 bits (176), Expect = 1e-11
Identities = 96/417 (23%), Positives = 186/417 (44%), Gaps = 42/417 (10%)
Query: 10 EFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTGGLHM 68
E++ + ++L + +Q+ ++ K ++ +G Y+ + + + SI+ G
Sbjct: 12 EYDQFVKEHELANVLQSSAWEEV--KSDWNHERLGVYEGENLLAVASILIKSLPLGYKMF 69
Query: 69 EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEFTGEGKPKGAPNTY 125
+ GP + + + LK + +++YA+S+ A+ + P Q + K + N
Sbjct: 70 YIPRGPILDYRDIELLKFVLQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEFPENLA 129
Query: 126 LIDDLTSIGYHHDGL--HIGYPGGEPDWHYVKNLEGITPQNLLK-SFSKKGRPLVKKAMS 182
+ID L +G G +G D + I +N + SK + ++ A +
Sbjct: 130 IIDSLQQMGVRWSGKTEEMG------DTIQPRIQAKIYKENFEEDKLSKSTKQAIRTARN 183
Query: 183 FGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREY 242
G++I+ E L F + T R++ ++ YY+ D+F DKA +ATL+ +
Sbjct: 184 KGVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLDVSK- 242
Query: 243 DHNLQLNAKKLEEQIT---VLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQ 299
+++LEEQ+ L+ +T ++K Q+ E +R E F+Q
Sbjct: 243 ------RSQELEEQLAKNRALEETFTESTRTSKVEAQKKE--------KERLLEELTFLQ 288
Query: 300 KF---GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFY 356
++ G V LA +L + + +V L++G +F ++ AP + + +R +
Sbjct: 289 EYMDAGQARVPLAATLTLEFGQTSVNLYAGMDEDFKRYKAPILTWYETARYTFERGILWQ 348
Query: 357 NFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKILRR 410
N G++ DG G+ RFK NFN I +G F +PL Y ++L +K LR+
Sbjct: 349 NLGGVENALDG--GLYRFKANFNPTIEEYLGEFTMPTHPL-YPLLRLALDFRKTLRK 402
>gi|11385678|gb|AAG34920.1|AF281139_1 MurM [Streptococcus
pneumoniae]
Length = 406
Score = 71.6 bits (174), Expect = 2e-11
Identities = 96/422 (22%), Positives = 190/422 (44%), Gaps = 44/422 (10%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVYTIPMT 63
+ A E++ + ++L + +Q+ ++ K ++ G + K+ + ++ T+P+
Sbjct: 8 IPALEYDQFVKEHELANVLQSSAWEEV--KSDWEHEKFGVYREEKLLATASILIRTLPL- 64
Query: 64 GGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEFTGEGKPKG 120
G + GP + +++ L + +++YA+S+ A+ + P Q + K +
Sbjct: 65 GYKMFYIPRGPILDYGDTELLSFVIQSIKSYARSKRAVFVTFDPSICLSQSLINQEKTEF 124
Query: 121 APNTYLIDDLTSIGYHHDGL--HIGYPGGEPDWHYVKNLEGITPQNLLK-SFSKKGRPLV 177
N +ID L +G G +G D + I +N + SK + +
Sbjct: 125 PENLAIIDSLQQMGVRWSGKTEEMG------DTIQPRIQAKIYKENFEEDKLSKSTKQAI 178
Query: 178 KKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATL 237
+ A + G++I+ E L F + T R++ ++ YY+ D+F DKA +ATL
Sbjct: 179 RTARNKGVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATL 238
Query: 238 NFREYDHNLQLNAKKLEEQIT---VLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEV 294
+ + +++LEEQ+ L+ +T ++K Q+ E +R E
Sbjct: 239 DVSK-------RSQELEEQLAKNRALEETFTESTRTSKVEAQKKE--------KERLLEE 283
Query: 295 EPFIQKF---GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKR 351
F+Q++ G V LA +L + + +V L++G +F ++ AP + + + +R
Sbjct: 284 LTFLQEYIDAGQARVPLAATLTLEFGQTSVNLYAGMDEDFRRYKAPILTWYETARYSFER 343
Query: 352 QSTFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKIL 408
+ N G++ DG G+ RFK NFN I +G F +PL Y ++L +K L
Sbjct: 344 GILWQNLGGVENALDG--GLYRFKANFNPTIEEYLGEFTIPTHPL-YPLLRLALDFRKTL 400
Query: 409 RR 410
R+
Sbjct: 401 RK 402
>gi|22536688|ref|NP_687539.1| beta-lactam resistance factor
[Streptococcus agalactiae 2603V/R]
gi|25010624|ref|NP_735019.1| Unknown [Streptococcus agalactiae
NEM316]
gi|22533529|gb|AAM99411.1|AE014215_5 beta-lactam resistance factor
[Streptococcus agalactiae 2603V/R]
gi|23094978|emb|CAD46199.1| Unknown [Streptococcus agalactiae
NEM316]
Length = 403
Score = 68.9 bits (167), Expect = 1e-10
Identities = 95/413 (23%), Positives = 173/413 (41%), Gaps = 41/413 (9%)
Query: 4 KELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS---IVYTI 60
+E+TA E + + + + +Q+ K+ K + +G+ DG+ +I S ++ ++
Sbjct: 3 REITAVEHDRFVSESNQTNLLQSSNWPKV--KDNWGSQLLGF-FDGETQIASASILIKSL 59
Query: 61 PMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTG---E 115
P+ G + + GP +SN + K+L+ + K Q AL + P + E
Sbjct: 60 PL-GFSMLYIPRGPIMDYSNLDIVTKVLKDLKAFGKKQRALFIKCDPLIYLKMVNAKDFE 118
Query: 116 GKPKGAPNTYLIDDLTSIGYHHDG-----LHIGYPGGEPDWHYVKNLEGITPQNLLKSFS 170
P ID L G G H P + NL Q L S
Sbjct: 119 NSPDEKEGLIAIDHLQRAGADWTGRTTDLAHTIQP------RFQANL--YANQFGLDKMS 170
Query: 171 KKGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKA 230
KK R ++ + + G+ I+ E L F ++ T DR+ + +DYYQ D++ + +
Sbjct: 171 KKTRQAIRTSKNKGVDIQFGSHELLEDFAELMKKTEDRKGINLRGIDYYQKLLDTYPNNS 230
Query: 231 EFVIATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKR 290
+A+L+ AK+LE+ S + +R++ +Q ++D+
Sbjct: 231 YITMASLDV----------AKRLEKIEKECQIAQSERIKSLELNREKKVKQHQ-GTIDRL 279
Query: 291 RKEVEPF--IQKFGNQDVV-LAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQE 347
KE++ QK ++D++ LA +L + + +++G F + AP Q
Sbjct: 280 NKEIDFLKEAQKAYDRDIIPLAATLTLEFGNTSENIYAGMDDYFKSYSAPIYTWFETAQR 339
Query: 348 ALKRQSTFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKS 400
A +R + + N GI+ + G G+ FK F I +G F N L YK+
Sbjct: 340 AFERGNIWQNMGGIENDLSG--GLYHFKSKFEPIIEEFIGEFNIPVNRLLYKA 390
>gi|15900523|ref|NP_345127.1| beta-lactam resistance factor
[Streptococcus pneumoniae TIGR4]
gi|25388504|pir||F95071 beta-lactam resistance factor [imported] -
Streptococcus pneumoniae (strain TIGR4)
gi|7649681|emb|CAB89120.1| beta-lactam resistance factor
[Streptococcus pneumoniae]
gi|14972091|gb|AAK74767.1| beta-lactam resistance factor
[Streptococcus pneumoniae TIGR4]
Length = 406
Score = 66.2 bits (160), Expect = 9e-10
Identities = 86/370 (23%), Positives = 166/370 (44%), Gaps = 40/370 (10%)
Query: 56 IVYTIPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEF 112
++ T+P+ G + GP + + + L + +++YA+S+ A+ + P Q
Sbjct: 58 LIRTLPL-GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAVFVTFDPSICLSQSL 116
Query: 113 TGEGKPKGAPNTYLIDDLTSIGYHHDGL--HIGYPGGEPDWHYVKNLEGITPQNLLK-SF 169
+ K + N +ID L +G G +G D + I +N +
Sbjct: 117 INQEKTEFPENLAIIDSLQQMGVRWSGKTEEMG------DTIQPRIQAKIYKENFEEDKL 170
Query: 170 SKKGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDK 229
SK + ++ A + G++I+ E L F ++ T R++ ++ YY+ D+F DK
Sbjct: 171 SKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDK 230
Query: 230 AEFVIATLNFREYDHNLQLNAKKLEEQIT---VLDNRHQNNTDSAKYHRQRTELVNQLAS 286
A +ATL+ + +++LEEQ+ L+ +T ++K Q+ E
Sbjct: 231 AYITLATLDVSK-------RSQELEEQLAKNRALEETFTESTRTSKVEAQKKE------- 276
Query: 287 LDKRRKEVEPFIQKF---GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEY 343
+R E F+Q++ G V LA +L + +V +++G +F ++ AP +
Sbjct: 277 -KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYE 335
Query: 344 VMQEALKRQSTFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL 403
+ A +R + N G++ + +G G+ FK+ FN I +G F +PL Y ++L
Sbjct: 336 TARYAFERGMIWQNLGGVENSLNG--GLYHFKEKFNPTIEEYLGEFTMPTHPL-YPLLRL 392
Query: 404 ---LKKILRR 410
+K LR+
Sbjct: 393 ALDFRKTLRK 402
>gi|15902584|ref|NP_358134.1| Serine/alanine adding enzyme
[Streptococcus pneumoniae R6]
gi|25508349|pir||D97939 serine/alanine adding enzyme [imported] -
Streptococcus pneumoniae (strain R6)
gi|7672298|emb|CAB89535.1| MurM protein [Streptococcus pneumoniae]
gi|15458115|gb|AAK99344.1| Serine/alanine adding enzyme
[Streptococcus pneumoniae R6]
gi|16605463|emb|CAC80802.1| MurM protein [Streptococcus pneumoniae]
Length = 406
Score = 65.1 bits (157), Expect = 2e-09
Identities = 85/370 (22%), Positives = 165/370 (43%), Gaps = 40/370 (10%)
Query: 56 IVYTIPMTGGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEF 112
++ T+P+ G + GP + + + L + +++YA+S+ + + P Q
Sbjct: 58 LIRTLPL-GYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRVVFVTFDPSICLSQSL 116
Query: 113 TGEGKPKGAPNTYLIDDLTSIGYHHDGL--HIGYPGGEPDWHYVKNLEGITPQNLLK-SF 169
+ K + N +ID L +G G +G D + I +N +
Sbjct: 117 INQEKTEFPENLAIIDSLQQMGVRWSGKTEEMG------DTIQPRIQAKIYKENFEEDKL 170
Query: 170 SKKGRPLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDK 229
SK + ++ A + G++I+ E L F ++ T R++ ++ YY+ D+F DK
Sbjct: 171 SKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKDK 230
Query: 230 AEFVIATLNFREYDHNLQLNAKKLEEQIT---VLDNRHQNNTDSAKYHRQRTELVNQLAS 286
A +ATL+ + +++LEEQ+ L+ +T ++K Q+ E
Sbjct: 231 AYITLATLDVSK-------RSQELEEQLAKNRALEETFTESTRTSKVEAQKKE------- 276
Query: 287 LDKRRKEVEPFIQKF---GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEY 343
+R E F+Q++ G V LA +L + +V +++G +F ++ AP +
Sbjct: 277 -KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWYE 335
Query: 344 VMQEALKRQSTFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL 403
+ A +R + N G++ + +G G+ FK+ FN I +G F +PL Y ++L
Sbjct: 336 TARYAFERGMVWQNLGGVENSLNG--GLYHFKEKFNPTIEEYLGEFTMPTHPL-YPLLRL 392
Query: 404 ---LKKILRR 410
+K LR+
Sbjct: 393 ALDFRKTLRK 402
>gi|12746259|gb|AAK07417.1| MurM [Streptococcus pneumoniae]
Length = 406
Score = 64.7 bits (156), Expect = 3e-09
Identities = 88/418 (21%), Positives = 188/418 (44%), Gaps = 36/418 (8%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTG 64
+ E++ + + + + +Q+ K+ K ++ +G Y+ + + + SI+ G
Sbjct: 8 IPVSEYDGFVKEHPMVNLLQSSAWEKV--KSDWNHERLGVYEGENLLAVASILIKSLPLG 65
Query: 65 GLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEFTGEGKPKGA 121
+ GP + +++ LK + +++YA+S+ A+ + P Q + K +
Sbjct: 66 YKMFYIPRGPILDYRDTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREYP 125
Query: 122 PNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQNLLK-SFSKKGRPLVKK 179
N +++ L +G G I E D ++ I +N + SK R ++
Sbjct: 126 ENLAIVEILGQLGVKWSGRTI-----EMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRT 180
Query: 180 AMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNF 239
A + G++I+ E L F ++ T R++ ++ YY+ D+F + + + +L+
Sbjct: 181 ARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDV 240
Query: 240 REYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYH-RQRTELVNQLASLDKRRKEVEPFI 298
+ ++LEEQ+ +N + K++ R+ V + +R KE F+
Sbjct: 241 SK-------RLRELEEQL------EKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFL 287
Query: 299 QKF---GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTF 355
Q + G ++ LA +L + +V L++G +F ++ AP + + A +R +
Sbjct: 288 QGYMNMGKSNIPLAATLSLEFGNTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVW 347
Query: 356 YNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKILRR 410
N G++ + +G G+ +FK+ FN I +G F +PL Y ++L +K LR+
Sbjct: 348 QNLGGVENSLNG--GLYQFKEKFNPTIEEYLGEFTMPTHPL-YPLLRLALDFRKTLRK 402
>gi|13324647|gb|AAK18829.1|AF327739_6 MurM [Streptococcus
thermophilus]
Length = 404
Score = 64.3 bits (155), Expect = 4e-09
Identities = 91/406 (22%), Positives = 173/406 (42%), Gaps = 44/406 (10%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTGG 65
L+ E + + + + +Q+ AK+ G D +G+ D K+ ++ V P+ G
Sbjct: 8 LSTSEHDRFVIDSPQTNLLQSSSWAKIKDSWGND--RLGFYQDDKLVAVASVLIQPLPLG 65
Query: 66 LHM-EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKP--YDTYQEFTGEGKPKG 120
M + GP + + + L L+ YAK++ AL + P + T + E
Sbjct: 66 FSMIYIPRGPIMDYQDKELLAFVITSLKKYAKTKRALFVKFDPSLFVTKNLISQE----- 120
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITPQNLLK------SFSKKGR 174
+ +D SI L + + G D +N++ N+ K SK +
Sbjct: 121 ---VNINEDTLSIAKDIQALGVEWTGLTED--MAENIQPRFQANIYKEDFTEEQLSKSTK 175
Query: 175 PLVKKAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVI 234
++ A + GI ++ E L F D+ T R++ + +DYY+ ++ + + +
Sbjct: 176 QAIRTARNKGISVQFGGTELLDQFADLMKKTEARKNIHLRGIDYYEKLLTTYPESSYITL 235
Query: 235 ATLNFREYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKY-HRQRTELVNQLASLDKRRKE 293
+TL +L K L +Q+ +N D+AK+ + + + KR E
Sbjct: 236 STL-------DLPARLKDLNKQL------EKNIADAAKFTEKTKPGKIENNKQEYKRLSE 282
Query: 294 VEPFIQK---FGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEY-VMQEAL 349
F+Q+ GN+ V L+G+L + +++G ++ + Y PA+L + A
Sbjct: 283 EIAFLQEKVDAGNKIVPLSGTLVLEFGNTAENIYAGMDEDYRR-YQPAILTWFETANHAF 341
Query: 350 KRQSTFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNP 395
+R + + N GI+ + DG G+ FK FN I + +G F +P
Sbjct: 342 ERGAEWQNMGGIENSLDG--GLYNFKSKFNPRIEQFIGEFNLPVSP 385
>gi|11385670|gb|AAG34916.1|AF281135_1 MurM [Streptococcus
pneumoniae]
Length = 406
Score = 64.3 bits (155), Expect = 4e-09
Identities = 88/414 (21%), Positives = 187/414 (44%), Gaps = 36/414 (8%)
Query: 10 EFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTGGLHM 68
E++ + + + + +Q+ K+ K ++ +G Y+ + + + SI+ G
Sbjct: 12 EYDGFVKEHPMVNLLQSSAWEKV--KSDWNHERLGVYEGENLLAVASILIKSLPLGYKMF 69
Query: 69 EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEFTGEGKPKGAPNTY 125
+ GP + +++ LK + +++YA+S+ A+ + P Q + K + N
Sbjct: 70 YIPRGPILDYRDTELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREYPENLA 129
Query: 126 LIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQNLLK-SFSKKGRPLVKKAMSF 183
+++ L +G G I E D ++ I +N + SK R ++ A +
Sbjct: 130 IVEILGQLGVKWSGRTI-----EMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 184 GIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYD 243
G++I+ E L F ++ T R++ ++ YY+ D+F + + + +L+ +
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYKKLLDNFKEDSYITLTSLDVSK-- 242
Query: 244 HNLQLNAKKLEEQITVLDNRHQNNTDSAKYH-RQRTELVNQLASLDKRRKEVEPFIQKF- 301
++LEEQ+ +N + K++ R+ V + +R KE F+Q +
Sbjct: 243 -----RLRELEEQL------EKNRVVAEKFNDATRSSKVQENIKEKERLKEEIDFLQGYM 291
Query: 302 --GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFL 359
G ++ LA +L + +V L++G +F ++ AP + + A +R + N
Sbjct: 292 NMGKSNIPLAATLSLEFGNTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVWQNLG 351
Query: 360 GIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKILRR 410
G++ + +G G+ +FK+ FN I +G F +PL Y ++L +K LR+
Sbjct: 352 GVENSLNG--GLYQFKEKFNPTIEEYLGEFTMPTHPL-YPLLRLALDFRKTLRK 402
>gi|18311072|ref|NP_563006.1| methicillin resistance factor
[Clostridium perfringens]
gi|18145754|dbj|BAB81796.1| methicillin resistance factor
[Clostridium perfringens str. 13]
Length = 445
Score = 63.5 bits (153), Expect = 5e-09
Identities = 94/430 (21%), Positives = 169/430 (38%), Gaps = 66/430 (15%)
Query: 5 ELTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIV------Y 58
E+ + E + ++ + QT A+ LKK GY D M I + + Y
Sbjct: 6 EINSSEIDKFNESDRKGHIFQTSYWAE-LKKDWKKKFIAGYDNDNNMVITATILLRKAPY 64
Query: 59 TIPMTGGLHMEVNSGPAHSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKP 118
G + ++N K L F + L+ +AK + I P D + + E
Sbjct: 65 INKYMGYIPRSFTCD--YNNKKLLIEFTEYLREFAKKNNISFITIDP-DIHLKENEEALS 121
Query: 119 KGAPNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEGITP---------------- 162
+G T + + L S+GY + KN E I P
Sbjct: 122 EG---TEIKNFLKSLGYKNTD--------------SKNFEAIQPNFVFRLPLPTEGNKMD 164
Query: 163 --QNLLKSFSKKGRPLVKKAMSFGIKIRVLKREELH-----IFKDITSSTSDRRDYMDKS 215
+ + K FS K R +K A G+ + V +E L+ F +I +T R +++ +
Sbjct: 165 IKKAVFKKFSSKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRH 224
Query: 216 LDYYQDFYDSFGDKAEFVIATLNFREYDHNLQLNAKKLEEQITVLDNRHQN-------NT 268
+Y++D D + ++ + L K EE T N+ + T
Sbjct: 225 REYFKDMIDYLYPHCRLYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDVET 284
Query: 269 DSAKYHRQRTELVNQLASLDKRRKEVEPF------IQKFGNQDVVLAGSLFIYSPKETVY 322
D K R +L +Q L + +++E F I+ F Q++ L+GS+++Y + Y
Sbjct: 285 DEDKKSRIEKKLNDQDKRLKEAERQIEGFKKKISDIEPFKGQEIYLSGSIYLYYGNKAWY 344
Query: 323 LFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLGIQGNFDGSD---GVLRFKQNFN 379
L+ S +Q ++ +++ Y+F G+ G+ + + G+ +FK+ FN
Sbjct: 345 LYGASENILRDTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFN 404
Query: 380 GYIVRKMGTF 389
G V +G F
Sbjct: 405 GNFVEFIGEF 414
>gi|11385676|gb|AAG34919.1|AF281138_1 MurM [Streptococcus
pneumoniae]
Length = 406
Score = 62.4 bits (150), Expect = 1e-08
Identities = 90/421 (21%), Positives = 187/421 (44%), Gaps = 42/421 (9%)
Query: 6 LTAKEFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIIS--IVYTIPMT 63
+ A E++ + +++L + +Q+ ++ K ++ G + K+ + ++ T+P+
Sbjct: 8 IPALEYDQFVKDHELANVLQSSAWEEV--KSDWEHEKFGVYREEKLLATASILIRTLPL- 64
Query: 64 GGLHMEVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEFTGEGKPKG 120
G + GP + +++ L + +++YA+S+ A+ + P Q + K +
Sbjct: 65 GYKMFYIPRGPILDYGDTELLSFVIQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKTEY 124
Query: 121 APNTYLIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQNLLK-SFSKKGRPLVK 178
+++ L +G G E D ++ I +N + SK + ++
Sbjct: 125 PEKLSIVEILGQLGVKWSGRTT-----EMDDTIQPRIQAKIYKENFEEDKLSKSTKQAIR 179
Query: 179 KAMSFGIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLN 238
A + G++I+ E L F + T R++ ++ YY+ D+F DKA +ATL+
Sbjct: 180 TARNKGVEIQFGGTELLESFSFLMKKTEKRKEIHLRNEAYYKKLLDNFKDKAYITLATLD 239
Query: 239 FREYDHNLQLNAKKLEEQIT---VLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVE 295
+ +++LEEQ+ L+ +T ++K Q+ E +R E
Sbjct: 240 VSK-------RSQELEEQLAKNRALEETFTESTRTSKVEAQKKE--------KERLLEEL 284
Query: 296 PFIQKF---GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQ 352
F+Q++ G V LA +L + +V L++G F ++ AP + + +R
Sbjct: 285 TFLQEYIDAGQARVPLAATLSLEFGTTSVNLYAGMDDAFKRYNAPILTWYETARYTFERG 344
Query: 353 STFYNFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKILR 409
+ N G++ + +G G+ FK+ FN I +G F +PL Y ++L +K LR
Sbjct: 345 MVWQNLGGVENSLNG--GLYHFKEKFNPTIEEYLGEFTMPTHPL-YPLLRLALDFRKTLR 401
Query: 410 R 410
+
Sbjct: 402 K 402
>gi|7672301|emb|CAB89537.1| MurM protein [Streptococcus pneumoniae]
gi|7672304|emb|CAB89539.1| MurM protein [Streptococcus pneumoniae]
Length = 406
Score = 61.6 bits (148), Expect = 2e-08
Identities = 90/417 (21%), Positives = 183/417 (43%), Gaps = 42/417 (10%)
Query: 10 EFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMG-YQIDGKMEIISIVYTIPMTGGLHM 68
E++ + ++L + +Q+ K+ K ++ +G Y+ + + + S++ G
Sbjct: 12 EYDQFVKEHELANVLQSSAWEKV--KSDWNHERLGVYEGENLLAVASVLIKSLPLGYKMF 69
Query: 69 EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTY-QEFTGEGKPKGAPNTY 125
+ GP + + + LK + +++YA+S+ A+ + P Q + K + N
Sbjct: 70 YIPRGPILDYMDKELLKFVLQSIKSYARSKRAVFVTFDPSICLSQHLVNQDKREYPENLA 129
Query: 126 LIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQNLLK-SFSKKGRPLVKKAMSF 183
+++ L +G G E D ++ I +N + SK R ++ A +
Sbjct: 130 IVEILGQLGVKWSG-----QTTEMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 184 GIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLN----F 239
G++I+ E L F ++ T R++ ++ YY+ D+F + + + L+
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEAYYRKLLDNFKEDSYITLTNLDVSKRL 244
Query: 240 REYDHNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVEPFIQ 299
RE + L N K LEE T +T ++K Q+ E + +D F+Q
Sbjct: 245 RELEEQLAKN-KALEEAFT-------ESTRTSKVEAQKKEKERLVEEID--------FLQ 288
Query: 300 KFGN---QDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFY 356
+ N ++ LA +L + +V L++G +F ++ AP + + A +R +
Sbjct: 289 GYMNMEKSNIPLAATLSLEFGTTSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMVWQ 348
Query: 357 NFLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKILRR 410
N G++ + +G G+ FK+ FN I +G F +PL Y ++L +K LR+
Sbjct: 349 NLGGVENSLNG--GLYHFKEKFNPTIEEYLGEFTMPTHPL-YPLLRLALDFRKTLRK 402
>gi|11385672|gb|AAG34917.1|AF281136_1 MurM [Streptococcus
pneumoniae]
Length = 406
Score = 58.5 bits (140), Expect = 2e-07
Identities = 87/414 (21%), Positives = 184/414 (44%), Gaps = 36/414 (8%)
Query: 10 EFESYSGNYDLQSFMQTPEMAKLLKKRGYDITYMGYQIDGKMEIISIVYTIPMTGGLHM- 68
E++ + ++L + +Q+ K+ K ++ G +GK+ ++ + + G M
Sbjct: 12 EYDQFVKEHELANVLQSSAWEKV--KSDWNHEKFGVYEEGKLLAVASILIKSLPLGYKMF 69
Query: 69 EVNSGPA--HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEF-TGEGKPKGAPNTY 125
+ GP + + + LK + +++YA+S+ A+ + P ++ + K + N
Sbjct: 70 YIPRGPILDYRDIELLKFVLQSIKSYARSKRAVFVTFDPSICLSQYLVNQDKIEYPENLA 129
Query: 126 LIDDLTSIGYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQNLLK-SFSKKGRPLVKKAMSF 183
+++ L +G G E D ++ I +N + SK R ++ A +
Sbjct: 130 IVEILGQLGVKWSGRTT-----EMDDTIQPRIQAKIYKENFEEDKLSKSTRQAIRTARNK 184
Query: 184 GIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYD 243
G++I+ E L F ++ T R++ ++ YY+ D+F + + + +L+ +
Sbjct: 185 GLEIQYGGLELLDSFSELMKKTEKRKEIHLRNETYYKKLLDNFKEDSYITLTSLDVSK-- 242
Query: 244 HNLQLNAKKLEEQITVLDNRHQNNTDSAKYHRQRTELVNQLASLDKRRKEVE-PFIQKF- 301
++LEEQ+ +N + K++ Q +K R E E F+Q +
Sbjct: 243 -----RLRELEEQL------EKNRVVAEKFNDATKPSKIQENIKEKERLEEEIDFLQGYM 291
Query: 302 --GNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFL 359
G ++ LA +L + +V L++G +F ++ AP + + A +R + N
Sbjct: 292 NMGKSNIPLAATLSLEFGITSVNLYAGMDDDFKRYNAPILTWYETARYAFERGMLWQNLG 351
Query: 360 GIQGNFDGSDGVLRFKQNFNGYIVRKMGTFRYYPNPLKYKSIQL---LKKILRR 410
G++ + +G G+ FK+ FN I +G F +PL Y ++L +K LR+
Sbjct: 352 GVENSLNG--GLYHFKEKFNPTIEEYLGEFTMPIHPL-YPLLRLALDFRKTLRK 402
>gi|19745722|ref|NP_606858.1| putative peptidoglycan branched
peptide synthesis protein, serine/alanine adding enzyme
[Streptococcus pyogenes MGAS8232]
gi|19747859|gb|AAL97357.1| putative peptidoglycan branched peptide
synthesis protein, serine/alanine adding enzyme
[Streptococcus pyogenes MGAS8232]
Length = 408
Score = 56.6 bits (135), Expect = 8e-07
Identities = 79/332 (23%), Positives = 131/332 (38%), Gaps = 49/332 (14%)
Query: 76 HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGAPNTYL--IDDLTSI 133
++N + L K L+ + KS+ AL + I P ++ T EGK + L I L +
Sbjct: 79 YANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQ-TLEGKESKENDVTLSIIAFLKKL 137
Query: 134 GYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQ---NL------LKSFSKKGRPLVKKAMSF 183
G G K LE I P+ N+ S KK + ++ A +
Sbjct: 138 GVEWSG-------------RTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 184 GIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYD 243
G+ + + E L F + T +R+ + + YYQ D + ++ +A+L+ E
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLDIYAGQSYITMASLDLPEQK 244
Query: 244 HNL-QLNAKKLEEQITVLDNRH-----QNNTDSAKYHRQRTELVNQLASLDKRRKEVEPF 297
L Q K L EQ + D +N A+ + T L QLA+
Sbjct: 245 KLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAA----------- 293
Query: 298 IQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYN 357
G + LA +L + + + L++G + + AP + +EA KR ++N
Sbjct: 294 ----GKTRIPLAATLTLIYGETSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHN 349
Query: 358 FLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTF 389
G++ DG G+ FK N I G F
Sbjct: 350 LGGVENQQDG--GLYHFKARLNPTIEEFAGEF 379
>gi|15674694|ref|NP_268868.1| putative peptidoglycan branched
peptide synthesis protein, serine/alanine adding enzyme
[Streptococcus pyogenes]
gi|13621813|gb|AAK33589.1| putative peptidoglycan branched peptide
synthesis protein, serine/alanine adding enzyme
[Streptococcus pyogenes M1 GAS]
Length = 408
Score = 55.1 bits (131), Expect = 2e-06
Identities = 78/332 (23%), Positives = 131/332 (38%), Gaps = 49/332 (14%)
Query: 76 HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGAPNTYL--IDDLTSI 133
++N + L K L+ + KS+ AL + I P ++ T EGK + L I L +
Sbjct: 79 YANFELLDFVIKTLKTFGKSKRALFIKIDPSLVIKQ-TLEGKESKENDVTLSIIAFLKKL 137
Query: 134 GYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQ---NL------LKSFSKKGRPLVKKAMSF 183
G G K LE I P+ N+ S KK + ++ A +
Sbjct: 138 GVEWSG-------------RTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 184 GIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYD 243
G+ + + E L F + T +R+ + + YYQ + ++ +A+L+ E
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDLPEQK 244
Query: 244 HNL-QLNAKKLEEQITVLDNRH-----QNNTDSAKYHRQRTELVNQLASLDKRRKEVEPF 297
L Q K L EQ + D +N A+ + T L QLA+
Sbjct: 245 KLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAT----------- 293
Query: 298 IQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYN 357
G + LA +L + + + L++G ++ + AP + +EA KR ++N
Sbjct: 294 ----GQTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWYETAKEAFKRGCRWHN 349
Query: 358 FLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTF 389
G++ DG G+ FK N I G F
Sbjct: 350 LGGVENQQDG--GLYHFKARLNPTIEEFAGEF 379
>gi|28896332|ref|NP_802682.1| putative peptidoglycan branched
peptide synthesis protein, serine/alanine adding enzyme
[Streptococcus pyogenes SSI-1]
gi|28811583|dbj|BAC64515.1| putative peptidoglycan branched peptide
synthesis protein, serine/alanine adding enzyme
[Streptococcus pyogenes SSI-1]
Length = 408
Score = 53.9 bits (128), Expect = 4e-06
Identities = 78/332 (23%), Positives = 130/332 (38%), Gaps = 49/332 (14%)
Query: 76 HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGAPNTYL--IDDLTSI 133
++N + L K L+ + KS+ AL + I P ++ T EGK + L I L +
Sbjct: 79 YANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQ-TLEGKESKENDVTLSIIAFLKKL 137
Query: 134 GYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQ---NL------LKSFSKKGRPLVKKAMSF 183
G G K LE I P+ N+ S KK + ++ A +
Sbjct: 138 GVEWSG-------------RTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 184 GIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYD 243
G+ + + E L F + T +R+ + + YYQ + ++ +A+L+ E
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDLPEQK 244
Query: 244 HNL-QLNAKKLEEQITVLDNRH-----QNNTDSAKYHRQRTELVNQLASLDKRRKEVEPF 297
L Q K L EQ + D +N A+ + T L QLA+
Sbjct: 245 KLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAA----------- 293
Query: 298 IQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYN 357
G + LA +L + + + L++G + + AP + +EA KR ++N
Sbjct: 294 ----GKTRIPLAATLTLIYGESSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHN 349
Query: 358 FLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTF 389
G++ DG G+ FK N I G F
Sbjct: 350 LGGVENQQDG--GLYHFKARLNPTIEEFAGEF 379
>gi|21909971|ref|NP_664239.1| putative peptidoglycan branched
peptide synthesis protein, serine/alanine adding enzyme
[Streptococcus pyogenes MGAS315]
gi|21904160|gb|AAM79042.1| putative peptidoglycan branched peptide
synthesis protein, serine/alanine adding enzyme
[Streptococcus pyogenes MGAS315]
Length = 408
Score = 53.9 bits (128), Expect = 5e-06
Identities = 78/332 (23%), Positives = 130/332 (38%), Gaps = 49/332 (14%)
Query: 76 HSNSKYLKHFYKELQNYAKSQGALELLIKPYDTYQEFTGEGKPKGAPNTYL--IDDLTSI 133
++N + L K L+ + KS+ AL + I P ++ T EGK + L I L +
Sbjct: 79 YANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQ-TLEGKESKENDVTLSIIAFLKKL 137
Query: 134 GYHHDGLHIGYPGGEPDWHYVKNLEG-ITPQ---NL------LKSFSKKGRPLVKKAMSF 183
G G K LE I P+ N+ S KK + ++ A +
Sbjct: 138 GVEWSG-------------RTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRTATNK 184
Query: 184 GIKIRVLKREELHIFKDITSSTSDRRDYMDKSLDYYQDFYDSFGDKAEFVIATLNFREYD 243
G+ + + E L F + T +R+ + + YYQ + ++ +A+L+ E
Sbjct: 185 GVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDLPEQK 244
Query: 244 HNL-QLNAKKLEEQITVLDNRH-----QNNTDSAKYHRQRTELVNQLASLDKRRKEVEPF 297
L Q K L EQ + D +N A+ + T L QLA+
Sbjct: 245 KLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAA----------- 293
Query: 298 IQKFGNQDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYN 357
G + LA +L + + + L++G + + AP + +EA KR ++N
Sbjct: 294 ----GKTRIPLAATLTLIYGESSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHN 349
Query: 358 FLGIQGNFDGSDGVLRFKQNFNGYIVRKMGTF 389
G++ DG G+ FK N I G F
Sbjct: 350 LGGVENQQDG--GLYHFKARLNPTIEEFTGEF 379
>gi|23024458|ref|ZP_00063669.1| hypothetical protein [Leuconostoc
mesenteroides subsp. mesenteroides ATCC 8293]
Length = 345
Score = 53.1 bits (126), Expect = 8e-06
Identities = 30/75 (40%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Query: 304 QDVVLAGSLFIYSPKETVYLFSGSYTEFNKFYAPAVLQEYVMQEALKRQSTFYNFLGIQG 363
+D V+A L E Y+++GSY EF K APA +Q +++ L+ Y+F GI G
Sbjct: 242 EDQVIASGLGFSYGDEIWYMYAGSYREFGKHNAPAAIQYEMLKWGLELGKVEYDFGGI-G 300
Query: 364 NFDGSDGVLRFKQNF 378
FD SDG+ +FK F
Sbjct: 301 EFDNSDGLYKFKHEF 315
Database: nr
Posted date: Aug 11, 2003 9:58 AM
Number of letters in database: 479,114,161
Number of sequences in database: 1,487,057
Lambda K H
0.318 0.137 0.396
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 402,401,480
Number of Sequences: 1487057
Number of extensions: 18272457
Number of successful extensions: 48329
Number of sequences better than 1.0e-04: 90
Number of HSP's better than 0.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 48029
Number of HSP's gapped (non-prelim): 91
length of query: 411
length of database: 479,114,161
effective HSP length: 126
effective length of query: 285
effective length of database: 291,744,979
effective search space: 83147319015
effective search space used: 83147319015
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 117 (49.7 bits)