BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= STr1701
(755 letters)
Database: nr
5,470,121 sequences; 1,894,087,724 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55821675|ref|YP_140117.1| penicillin binding protein 2X ... 1341 0.0
gi|116628388|ref|YP_821007.1| Cell division protein FtsI/pe... 1329 0.0
gi|24378943|ref|NP_720898.1| putative penicillin-binding pr... 826 0.0
gi|50914759|ref|YP_060731.1| Division specific D,D-transpep... 801 0.0
gi|28895373|ref|NP_801723.1| putative penicillin binding pr... 801 0.0
gi|15675531|ref|NP_269705.1| putative penicillin binding pr... 800 0.0
gi|94988993|ref|YP_597094.1| cell division protein ftsI [St... 797 0.0
gi|21910937|ref|NP_665205.1| putative penicillin binding pr... 766 0.0
gi|77408178|ref|ZP_00784923.1| penicillin-binding protein 2... 756 0.0
gi|22536471|ref|NP_687322.1| penicillin-binding protein 2X ... 754 0.0
gi|25010351|ref|NP_734746.1| hypothetical protein gbs0277 [... 753 0.0
gi|81097077|ref|ZP_00875390.1| Peptidoglycan glycosyltransf... 743 0.0
gi|146319396|ref|YP_001199108.1| Cell division protein FtsI... 743 0.0
gi|38142227|dbj|BAD00916.1| penicillin-binding protein 2X [... 723 0.0
gi|38142269|dbj|BAD00937.1| penicillin-binding protein 2X [... 721 0.0
gi|149018028|ref|ZP_01834487.1| S-adenosyl-methyltransferas... 721 0.0
gi|38142209|dbj|BAD00907.1| penicillin-binding protein 2X [... 720 0.0
gi|38142201|dbj|BAD00903.1| penicillin-binding protein 2X [... 719 0.0
gi|76787444|ref|YP_329011.1| penicillin-binding protein 2X ... 719 0.0
gi|15900267|ref|NP_344871.1| penicillin-binding protein 2X ... 719 0.0
gi|116517037|ref|YP_815823.1| penicillin-binding protein 2X... 719 0.0
gi|38142235|dbj|BAD00920.1| penicillin-binding protein 2X [... 718 0.0
gi|55167243|dbj|BAD67448.1| penicillin-binding protein 2X [... 718 0.0
gi|148996750|ref|ZP_01824468.1| S-adenosyl-methyltransferas... 718 0.0
gi|6563353|gb|AAF17263.1|AF210753_1 penicillin-binding prot... 718 0.0
gi|38142219|dbj|BAD00912.1| penicillin-binding protein 2X [... 718 0.0
gi|148988092|ref|ZP_01819555.1| S-adenosyl-methyltransferas... 718 0.0
gi|6563367|gb|AAF17270.1|AF210760_1 penicillin-binding prot... 718 0.0
gi|6563357|gb|AAF17265.1|AF210755_1 penicillin-binding prot... 717 0.0
gi|38142231|dbj|BAD00918.1| penicillin-binding protein 2X [... 717 0.0
gi|15902348|ref|NP_357898.1| Penicillin-binding protein 2X ... 717 0.0
gi|38142203|dbj|BAD00904.1| penicillin-binding protein 2X [... 717 0.0
gi|6563359|gb|AAF17266.1|AF210756_1 penicillin-binding prot... 717 0.0
gi|148994364|ref|ZP_01823607.1| S-adenosyl-methyltransferas... 717 0.0
gi|38142199|dbj|BAD00902.1| penicillin-binding protein 2X [... 716 0.0
gi|38142205|dbj|BAD00905.1| penicillin-binding protein 2X [... 716 0.0
gi|38142241|dbj|BAD00923.1| penicillin-binding protein 2X [... 716 0.0
gi|38142247|dbj|BAD00926.1| penicillin-binding protein 2X [... 715 0.0
gi|38142259|dbj|BAD00932.1| penicillin-binding protein 2X [... 715 0.0
gi|6563363|gb|AAF17268.1|AF210758_1 penicillin-binding prot... 715 0.0
gi|38142213|dbj|BAD00909.1| penicillin-binding protein 2X [... 714 0.0
gi|6563361|gb|AAF17267.1|AF210757_1 penicillin-binding prot... 714 0.0
gi|38142207|dbj|BAD00906.1| penicillin-binding protein 2X [... 714 0.0
gi|38142215|dbj|BAD00910.1| penicillin-binding protein 2X [... 714 0.0
gi|38142245|dbj|BAD00925.1| penicillin-binding protein 2X [... 714 0.0
gi|38142271|dbj|BAD00938.1| penicillin-binding protein 2X [... 713 0.0
gi|38142221|dbj|BAD00913.1| penicillin-binding protein 2X [... 713 0.0
gi|38142267|dbj|BAD00936.1| penicillin-binding protein 2X [... 713 0.0
gi|38142249|dbj|BAD00927.1| penicillin-binding protein 2X [... 713 0.0
gi|38142265|dbj|BAD00935.1| penicillin-binding protein 2X [... 712 0.0
gi|38142253|dbj|BAD00929.1| penicillin-binding protein 2X [... 712 0.0
gi|38142223|dbj|BAD00914.1| penicillin-binding protein 2X [... 711 0.0
gi|38142229|dbj|BAD00917.1| penicillin-binding protein 2X [... 711 0.0
gi|148714948|gb|ABR03900.1| penicillin-binding protein 2x [... 711 0.0
gi|38142273|dbj|BAD00939.1| penicillin-binding protein 2X [... 710 0.0
gi|18652354|gb|AAL77081.1|AF468152_1 penicillin-binding pro... 710 0.0
gi|148714872|gb|ABR03862.1| penicillin-binding protein 2x [... 710 0.0
gi|148715106|gb|ABR03979.1| penicillin-binding protein 2x [... 709 0.0
gi|148714904|gb|ABR03878.1| penicillin-binding protein 2x [... 709 0.0
gi|38142233|dbj|BAD00919.1| penicillin-binding protein 2X [... 709 0.0
gi|148714866|gb|ABR03859.1| penicillin-binding protein 2x [... 709 0.0
gi|38142239|dbj|BAD00922.1| penicillin-binding protein 2X [... 709 0.0
gi|6563355|gb|AAF17264.1|AF210754_1 penicillin-binding prot... 709 0.0
gi|148715114|gb|ABR03983.1| penicillin-binding protein 2x [... 709 0.0
gi|148714940|gb|ABR03896.1| penicillin-binding protein 2x [... 709 0.0
gi|148714876|gb|ABR03864.1| penicillin-binding protein 2x [... 708 0.0
gi|148715172|gb|ABR04012.1| penicillin-binding protein 2x [... 708 0.0
gi|148714902|gb|ABR03877.1| penicillin-binding protein 2x [... 708 0.0
gi|2315993|gb|AAC45547.1| low-affinity penicillin-binding p... 707 0.0
gi|148714914|gb|ABR03883.1| penicillin-binding protein 2x [... 707 0.0
gi|148714862|gb|ABR03857.1| penicillin-binding protein 2x [... 707 0.0
gi|148715282|gb|ABR04067.1| penicillin-binding protein 2x [... 707 0.0
gi|148715132|gb|ABR03992.1| penicillin-binding protein 2x [... 707 0.0
gi|148715096|gb|ABR03974.1| penicillin-binding protein 2x [... 707 0.0
gi|148714958|gb|ABR03905.1| penicillin-binding protein 2x [... 706 0.0
gi|6563365|gb|AAF17269.1|AF210759_1 penicillin-binding prot... 706 0.0
gi|148715090|gb|ABR03971.1| penicillin-binding protein 2x [... 706 0.0
gi|38142275|dbj|BAD00940.1| penicillin-binding protein 2X [... 706 0.0
gi|148715118|gb|ABR03985.1| penicillin-binding protein 2x [... 706 0.0
gi|148715248|gb|ABR04050.1| penicillin-binding protein 2x [... 706 0.0
gi|148715156|gb|ABR04004.1| penicillin-binding protein 2x [... 706 0.0
gi|148715126|gb|ABR03989.1| penicillin-binding protein 2x [... 706 0.0
gi|148714890|gb|ABR03871.1| penicillin-binding protein 2x [... 706 0.0
gi|148714932|gb|ABR03892.1| penicillin-binding protein 2x [... 706 0.0
gi|148715144|gb|ABR03998.1| penicillin-binding protein 2x [... 706 0.0
gi|148715210|gb|ABR04031.1| penicillin-binding protein 2x [... 706 0.0
gi|148714920|gb|ABR03886.1| penicillin-binding protein 2x [... 706 0.0
gi|125718669|ref|YP_001035802.1| Penicillin-binding protein... 705 0.0
gi|148714868|gb|ABR03860.1| penicillin-binding protein 2x [... 705 0.0
gi|148714930|gb|ABR03891.1| penicillin-binding protein 2x [... 705 0.0
gi|148715238|gb|ABR04045.1| penicillin-binding protein 2x [... 705 0.0
gi|148714954|gb|ABR03903.1| penicillin-binding protein 2x [... 705 0.0
gi|148715288|gb|ABR04070.1| penicillin-binding protein 2x [... 705 0.0
gi|148715116|gb|ABR03984.1| penicillin-binding protein 2x [... 705 0.0
gi|148715244|gb|ABR04048.1| penicillin-binding protein 2x [... 704 0.0
gi|148714864|gb|ABR03858.1| penicillin-binding protein 2x [... 704 0.0
gi|148715142|gb|ABR03997.1| penicillin-binding protein 2x [... 704 0.0
gi|148715064|gb|ABR03958.1| penicillin-binding protein 2x [... 704 0.0
gi|148714966|gb|ABR03909.1| penicillin-binding protein 2x [... 704 0.0
gi|148715264|gb|ABR04058.1| penicillin-binding protein 2x [... 704 0.0
gi|148715280|gb|ABR04066.1| penicillin-binding protein 2x [... 704 0.0
gi|148715102|gb|ABR03977.1| penicillin-binding protein 2x [... 704 0.0
gi|148714908|gb|ABR03880.1| penicillin-binding protein 2x [... 704 0.0
gi|148714884|gb|ABR03868.1| penicillin-binding protein 2x [... 704 0.0
gi|148715124|gb|ABR03988.1| penicillin-binding protein 2x [... 704 0.0
gi|148714924|gb|ABR03888.1| penicillin-binding protein 2x [... 704 0.0
gi|148714910|gb|ABR03881.1| penicillin-binding protein 2x [... 704 0.0
gi|148715086|gb|ABR03969.1| penicillin-binding protein 2x [... 704 0.0
gi|148715018|gb|ABR03935.1| penicillin-binding protein 2x [... 704 0.0
gi|38142225|dbj|BAD00915.1| penicillin-binding protein 2X [... 704 0.0
gi|148714896|gb|ABR03874.1| penicillin-binding protein 2x [... 704 0.0
gi|148715010|gb|ABR03931.1| penicillin-binding protein 2x [... 704 0.0
gi|148714878|gb|ABR03865.1| penicillin-binding protein 2x [... 704 0.0
gi|148715082|gb|ABR03967.1| penicillin-binding protein 2x [... 704 0.0
gi|148715080|gb|ABR03966.1| penicillin-binding protein 2x [... 703 0.0
gi|148715178|gb|ABR04015.1| penicillin-binding protein 2x [... 702 0.0
gi|148715058|gb|ABR03955.1| penicillin-binding protein 2x [... 702 0.0
gi|148715072|gb|ABR03962.1| penicillin-binding protein 2x [... 702 0.0
gi|148715050|gb|ABR03951.1| penicillin-binding protein 2x [... 702 0.0
gi|148715160|gb|ABR04006.1| penicillin-binding protein 2x [... 702 0.0
gi|148715008|gb|ABR03930.1| penicillin-binding protein 2x [... 702 0.0
gi|148714972|gb|ABR03912.1| penicillin-binding protein 2x [... 702 0.0
gi|157075965|gb|ABV10648.1| penicillin-binding protein 2X [... 702 0.0
gi|148715278|gb|ABR04065.1| penicillin-binding protein 2x [... 702 0.0
gi|148715074|gb|ABR03963.1| penicillin-binding protein 2x [... 701 0.0
gi|148715206|gb|ABR04029.1| penicillin-binding protein 2x [... 701 0.0
gi|38142251|dbj|BAD00928.1| penicillin-binding protein 2X [... 701 0.0
gi|148715056|gb|ABR03954.1| penicillin-binding protein 2x [... 701 0.0
gi|148715078|gb|ABR03965.1| penicillin-binding protein 2x [... 701 0.0
gi|148714938|gb|ABR03895.1| penicillin-binding protein 2x [... 701 0.0
gi|148715052|gb|ABR03952.1| penicillin-binding protein 2x [... 701 0.0
gi|148715184|gb|ABR04018.1| penicillin-binding protein 2x [... 701 0.0
gi|148714976|gb|ABR03914.1| penicillin-binding protein 2x [... 701 0.0
gi|148715146|gb|ABR03999.1| penicillin-binding protein 2x [... 701 0.0
gi|148715158|gb|ABR04005.1| penicillin-binding protein 2x [... 701 0.0
gi|148715268|gb|ABR04060.1| penicillin-binding protein 2x [... 701 0.0
gi|148714968|gb|ABR03910.1| penicillin-binding protein 2x [... 701 0.0
gi|148715068|gb|ABR03960.1| penicillin-binding protein 2x [... 700 0.0
gi|148715226|gb|ABR04039.1| penicillin-binding protein 2x [... 700 0.0
gi|148715202|gb|ABR04027.1| penicillin-binding protein 2x [... 699 0.0
gi|148714978|gb|ABR03915.1| penicillin-binding protein 2x [... 699 0.0
gi|148715216|gb|ABR04034.1| penicillin-binding protein 2x [... 699 0.0
gi|148715122|gb|ABR03987.1| penicillin-binding protein 2x [... 699 0.0
gi|148715046|gb|ABR03949.1| penicillin-binding protein 2x [... 699 0.0
gi|148714990|gb|ABR03921.1| penicillin-binding protein 2x [... 698 0.0
gi|148715250|gb|ABR04051.1| penicillin-binding protein 2x [... 698 0.0
gi|148714962|gb|ABR03907.1| penicillin-binding protein 2x [... 698 0.0
gi|148715100|gb|ABR03976.1| penicillin-binding protein 2x [... 697 0.0
gi|148715220|gb|ABR04036.1| penicillin-binding protein 2x [... 697 0.0
gi|148715236|gb|ABR04044.1| penicillin-binding protein 2x [... 697 0.0
gi|148715200|gb|ABR04026.1| penicillin-binding protein 2x [... 697 0.0
gi|148715092|gb|ABR03972.1| penicillin-binding protein 2x [... 697 0.0
gi|148715060|gb|ABR03956.1| penicillin-binding protein 2x [... 697 0.0
gi|148714894|gb|ABR03873.1| penicillin-binding protein 2x [... 696 0.0
gi|148715148|gb|ABR04000.1| penicillin-binding protein 2x [... 695 0.0
gi|148715222|gb|ABR04037.1| penicillin-binding protein 2x [... 694 0.0
gi|148715274|gb|ABR04063.1| penicillin-binding protein 2x [... 694 0.0
gi|148714946|gb|ABR03899.1| penicillin-binding protein 2x [... 694 0.0
gi|148715044|gb|ABR03948.1| penicillin-binding protein 2x [... 693 0.0
gi|148715252|gb|ABR04052.1| penicillin-binding protein 2x [... 693 0.0
gi|148715162|gb|ABR04007.1| penicillin-binding protein 2x [... 692 0.0
gi|148714900|gb|ABR03876.1| penicillin-binding protein 2x [... 691 0.0
gi|38142211|dbj|BAD00908.1| penicillin-binding protein 2X [... 691 0.0
gi|148714898|gb|ABR03875.1| penicillin-binding protein 2x [... 690 0.0
gi|148715134|gb|ABR03993.1| penicillin-binding protein 2x [... 689 0.0
gi|148715130|gb|ABR03991.1| penicillin-binding protein 2x [... 689 0.0
gi|148715000|gb|ABR03926.1| penicillin-binding protein 2x [... 688 0.0
gi|148715076|gb|ABR03964.1| penicillin-binding protein 2x [... 687 0.0
gi|148715270|gb|ABR04061.1| penicillin-binding protein 2x [... 687 0.0
gi|148715188|gb|ABR04020.1| penicillin-binding protein 2x [... 686 0.0
gi|148715262|gb|ABR04057.1| penicillin-binding protein 2x [... 686 0.0
gi|148715176|gb|ABR04014.1| penicillin-binding protein 2x [... 685 0.0
gi|148715230|gb|ABR04041.1| penicillin-binding protein 2x [... 684 0.0
gi|148715272|gb|ABR04062.1| penicillin-binding protein 2x [... 682 0.0
gi|148715290|gb|ABR04071.1| penicillin-binding protein 2x [... 676 0.0
gi|148715208|gb|ABR04030.1| penicillin-binding protein 2x [... 674 0.0
gi|148715260|gb|ABR04056.1| penicillin-binding protein 2x [... 672 0.0
gi|148715198|gb|ABR04025.1| penicillin-binding protein 2x [... 671 0.0
gi|8569396|pdb|1QME|A Chain A, Penicillin-Binding Protein 2... 669 0.0
gi|148715240|gb|ABR04046.1| penicillin-binding protein 2x [... 669 0.0
gi|42543579|pdb|1RP5|A Chain A, Pbp2x From Streptococcus Pn... 669 0.0
gi|148715234|gb|ABR04043.1| penicillin-binding protein 2x [... 669 0.0
gi|30519792|emb|CAD90770.1| penicillin-binding protein 2x [... 667 0.0
gi|148714988|gb|ABR03920.1| penicillin-binding protein 2x [... 667 0.0
gi|37927671|pdb|1PYY|A Chain A, Double Mutant Pbp2x T338aM3... 666 0.0
gi|53748611|emb|CAD90771.2| penicillin-binding protein 2x [... 665 0.0
gi|148714922|gb|ABR03887.1| penicillin-binding protein 2x [... 656 0.0
gi|148714984|gb|ABR03918.1| penicillin-binding protein 2x [... 656 0.0
gi|148714960|gb|ABR03906.1| penicillin-binding protein 2x [... 655 0.0
gi|148715098|gb|ABR03975.1| penicillin-binding protein 2x [... 654 0.0
gi|16974968|pdb|1K25|A Chain A, Pbp2x From A Highly Penicil... 653 0.0
gi|148714912|gb|ABR03882.1| penicillin-binding protein 2x [... 652 0.0
gi|148714956|gb|ABR03904.1| penicillin-binding protein 2x [... 651 0.0
gi|149001554|ref|ZP_01826527.1| Penicillin-binding protein ... 650 0.0
gi|1942406|pdb|1PMD| Chain , Penicillin-Binding Protein 2... 650 0.0
gi|148715062|gb|ABR03957.1| penicillin-binding protein 2x [... 645 0.0
gi|154794062|gb|ABS86079.1| penicillin-binding protein 2x [... 642 0.0
gi|1781320|emb|CAA55062.1| penicilin-binding protein [Strep... 641 0.0
gi|66817098|gb|AAY56848.1| penicillin-binding protein 2X [S... 640 0.0
gi|66817084|gb|AAY56841.1| penicillin-binding protein 2X [S... 638 0.0
gi|66817080|gb|AAY56839.1| penicillin-binding protein 2X [S... 638 0.0
gi|6689319|emb|CAB65444.1| penicillin binding protein 2x [S... 637 0.0
gi|10178942|emb|CAC08465.1| penicillin binding protein 2x [... 637 e-180
gi|66817110|gb|AAY56854.1| penicillin-binding protein 2X [S... 636 e-180
gi|517186|emb|CAA55061.1| penicilin-binding protein [Strept... 635 e-180
gi|66817100|gb|AAY56849.1| penicillin-binding protein 2X [S... 635 e-180
gi|66817106|gb|AAY56852.1| penicillin-binding protein 2X [S... 635 e-180
gi|66817086|gb|AAY56842.1| penicillin-binding protein 2X [S... 634 e-180
gi|66817102|gb|AAY56850.1| penicillin-binding protein 2X [S... 634 e-180
gi|66817094|gb|AAY56846.1| penicillin-binding protein 2X [S... 634 e-180
gi|66817112|gb|AAY56855.1| penicillin-binding protein 2X [S... 633 e-179
gi|66817078|gb|AAY56838.1| penicillin-binding protein 2X [S... 633 e-179
gi|6689325|emb|CAB65447.1| penicillin binding protein 2x [S... 633 e-179
gi|47330|emb|CAA46265.1| penicillin binding protein 2x [Str... 633 e-179
gi|1553053|emb|CAA67013.1| penicillin-binding protein [Stre... 633 e-179
gi|66817114|gb|AAY56856.1| penicillin-binding protein 2X [S... 632 e-179
gi|23451806|gb|AAN32865.1| penicillin-binding protein 2X [S... 632 e-179
gi|66817104|gb|AAY56851.1| penicillin-binding protein 2X [S... 632 e-179
gi|2253201|emb|CAA71561.1| pbp2x [Streptococcus mitis] 632 e-179
gi|66817096|gb|AAY56847.1| penicillin-binding protein 2X [S... 632 e-179
gi|1553055|emb|CAA67010.1| penicillin-binding protein [Stre... 631 e-179
gi|559528|emb|CAA46266.1| penicillin binding protein 2x [St... 631 e-179
gi|1553049|emb|CAA67011.1| penicillin-binding protein [Stre... 630 e-178
gi|6689323|emb|CAB65446.1| penicillin binding protein 2x [S... 630 e-178
gi|47336|emb|CAA46264.1| penicillin binding protein 2x [Str... 630 e-178
gi|2253209|emb|CAA71564.1| pbp2X [Streptococcus oralis] 629 e-178
gi|6689321|emb|CAB65445.1| penicillin binding protein 2x [S... 629 e-178
gi|2253203|emb|CAA71562.1| pbp2x [Streptococcus mitis] 629 e-178
gi|23451791|gb|AAN32859.1| penicillin-binding protein 2X [S... 629 e-178
gi|2253205|emb|CAA71560.1| pbp2X [Streptococcus mitis] 629 e-178
gi|66817088|gb|AAY56843.1| penicillin-binding protein 2X [S... 628 e-178
gi|23451785|gb|AAN32857.1| penicillin-binding protein 2X [S... 628 e-178
gi|66817092|gb|AAY56845.1| penicillin-binding protein 2X [S... 628 e-178
gi|66817082|gb|AAY56840.1| penicillin-binding protein 2X [S... 628 e-178
gi|886957|emb|CAA88920.1| penicillin-binding protein 2x [St... 628 e-178
gi|154794050|gb|ABS86073.1| penicillin-binding protein 2x [... 627 e-178
gi|66817116|gb|AAY56857.1| penicillin-binding protein 2X [S... 627 e-178
gi|2982614|emb|CAA05299.1| penicillin-binding protein 2x [S... 627 e-178
gi|886955|emb|CAA88919.1| penicillin-binding protein 2x [St... 627 e-177
gi|6689313|emb|CAB65441.1| penicillin binding protein 2x [S... 627 e-177
gi|1553051|emb|CAA67012.1| penicillin-binding protein [Stre... 627 e-177
gi|47332|emb|CAA46263.1| penicillin binding protein 2x [Str... 627 e-177
gi|6689379|emb|CAB65448.1| penicillin binding protein 2x [S... 626 e-177
gi|517191|emb|CAA55060.1| penicilin-binding protein [Strept... 626 e-177
gi|23451782|gb|AAN32856.1| penicillin-binding protein 2X [S... 626 e-177
gi|154794056|gb|ABS86076.1| penicillin-binding protein 2x [... 625 e-177
gi|23451798|gb|AAN32862.1| penicillin-binding protein 2X [S... 624 e-177
gi|47308|emb|CAA46261.1| penicillin binding protein 2x [Str... 624 e-177
gi|6689315|emb|CAB65442.1| penicillin binding protein 2x [S... 624 e-177
gi|2253207|emb|CAA71563.1| pbp2x [Streptococcus mitis] 623 e-176
gi|78707406|gb|ABB46504.1| penicillin binding protein 2x [S... 623 e-176
gi|6689317|emb|CAB65443.1| penicillin binding protein 2x [S... 623 e-176
gi|148714916|gb|ABR03884.1| penicillin-binding protein 2x [... 623 e-176
gi|23451773|gb|AAN32852.1| penicillin-binding protein 2X [S... 622 e-176
gi|47338|emb|CAA46262.1| penicillin binding protein 2x [Str... 622 e-176
gi|23451779|gb|AAN32855.1| penicillin-binding protein 2X [S... 622 e-176
gi|23451801|gb|AAN32863.1| penicillin-binding protein 2X [S... 621 e-176
gi|23451803|gb|AAN32864.1| penicillin-binding protein 2X [S... 620 e-175
gi|23451794|gb|AAN32860.1| penicillin-binding protein 2X [S... 619 e-175
gi|78707414|gb|ABB46508.1| penicillin binding protein 2x [S... 619 e-175
gi|154794068|gb|ABS86082.1| penicillin-binding protein 2x [... 619 e-175
gi|66817108|gb|AAY56853.1| penicillin-binding protein 2X [S... 619 e-175
gi|78707416|gb|ABB46509.1| penicillin binding protein 2x [S... 619 e-175
gi|23451796|gb|AAN32861.1| penicillin-binding protein 2X [S... 617 e-175
gi|78707410|gb|ABB46506.1| penicillin binding protein 2x [S... 617 e-175
gi|78707408|gb|ABB46505.1| penicillin binding protein 2x [S... 617 e-175
gi|10178933|emb|CAC08461.1| penicillin binding protein 2x [... 617 e-174
gi|154794066|gb|ABS86081.1| penicillin-binding protein 2x [... 615 e-174
gi|154794054|gb|ABS86075.1| penicillin-binding protein 2x [... 611 e-173
gi|154794060|gb|ABS86078.1| penicillin-binding protein 2x [... 609 e-172
gi|154794072|gb|ABS86084.1| penicillin-binding protein 2x [... 604 e-171
gi|154794070|gb|ABS86083.1| penicillin-binding protein 2x [... 604 e-171
gi|14588965|emb|CAC43044.1| penicillin-binding protein 2x [... 603 e-170
gi|154794064|gb|ABS86080.1| penicillin-binding protein 2x [... 600 e-170
gi|154794052|gb|ABS86074.1| penicillin-binding protein 2x [... 599 e-169
gi|14588967|emb|CAC43045.1| penicillin-binding protein 2x [... 594 e-168
gi|154794058|gb|ABS86077.1| penicillin-binding protein 2x [... 590 e-166
gi|148714874|gb|ABR03863.1| penicillin-binding protein 2x [... 588 e-166
gi|148714888|gb|ABR03870.1| penicillin-binding protein 2x [... 587 e-166
gi|148714870|gb|ABR03861.1| penicillin-binding protein 2x [... 587 e-166
gi|148715186|gb|ABR04019.1| penicillin-binding protein 2x [... 585 e-165
gi|148715042|gb|ABR03947.1| penicillin-binding protein 2x [... 583 e-164
gi|148715276|gb|ABR04064.1| penicillin-binding protein 2x [... 583 e-164
gi|148714982|gb|ABR03917.1| penicillin-binding protein 2x [... 583 e-164
gi|148714950|gb|ABR03901.1| penicillin-binding protein 2x [... 582 e-164
gi|148715242|gb|ABR04047.1| penicillin-binding protein 2x [... 580 e-163
gi|148714880|gb|ABR03866.1| penicillin-binding protein 2x [... 578 e-163
gi|148715224|gb|ABR04038.1| penicillin-binding protein 2x [... 576 e-162
gi|148715054|gb|ABR03953.1| penicillin-binding protein 2x [... 570 e-160
gi|148715284|gb|ABR04068.1| penicillin-binding protein 2x [... 560 e-157
gi|148714926|gb|ABR03889.1| penicillin-binding protein 2x [... 549 e-154
gi|62765948|gb|AAX99190.1| penicillin binding protein [Stre... 548 e-154
gi|62765982|gb|AAX99207.1| penicillin binding protein [Stre... 548 e-154
gi|62765908|gb|AAX99170.1| penicillin binding protein [Stre... 546 e-153
gi|62765924|gb|AAX99178.1| penicillin binding protein [Stre... 546 e-153
gi|62765942|gb|AAX99187.1| penicillin binding protein [Stre... 546 e-153
gi|62765980|gb|AAX99206.1| penicillin binding protein [Stre... 546 e-153
gi|156447813|gb|ABU63684.1| penicillin-binding protein 2X [... 545 e-153
gi|62765978|gb|AAX99205.1| penicillin binding protein [Stre... 545 e-153
gi|62765956|gb|AAX99194.1| penicillin binding protein [Stre... 545 e-153
gi|62765992|gb|AAX99212.1| penicillin binding protein [Stre... 545 e-153
gi|62765960|gb|AAX99196.1| penicillin binding protein [Stre... 545 e-153
gi|62765984|gb|AAX99208.1| penicillin binding protein [Stre... 545 e-153
gi|62765916|gb|AAX99174.1| penicillin binding protein [Stre... 545 e-153
gi|157057035|gb|ABV02556.1| penicillin-binding protein 2X [... 544 e-153
gi|62765988|gb|AAX99210.1| penicillin binding protein [Stre... 544 e-153
gi|62765986|gb|AAX99209.1| penicillin binding protein [Stre... 544 e-153
gi|62765958|gb|AAX99195.1| penicillin binding protein [Stre... 544 e-153
gi|62765936|gb|AAX99184.1| penicillin binding protein [Stre... 544 e-153
gi|62765928|gb|AAX99180.1| penicillin binding protein [Stre... 544 e-152
gi|157057029|gb|ABV02553.1| penicillin-binding protein 2X [... 543 e-152
gi|62765900|gb|AAX99166.1| penicillin binding protein [Stre... 543 e-152
gi|62765990|gb|AAX99211.1| penicillin binding protein [Stre... 543 e-152
gi|62765920|gb|AAX99176.1| penicillin binding protein [Stre... 543 e-152
gi|156447815|gb|ABU63685.1| penicillin-binding protein 2X [... 543 e-152
gi|156447817|gb|ABU63686.1| penicillin-binding protein 2X [... 542 e-152
gi|156447819|gb|ABU63687.1| penicillin-binding protein 2X [... 542 e-152
gi|62765944|gb|AAX99188.1| penicillin binding protein [Stre... 542 e-152
gi|62765898|gb|AAX99165.1| penicillin binding protein [Stre... 542 e-152
gi|62765922|gb|AAX99177.1| penicillin binding protein [Stre... 542 e-152
gi|62765932|gb|AAX99182.1| penicillin binding protein [Stre... 542 e-152
gi|62765940|gb|AAX99186.1| penicillin binding protein [Stre... 541 e-152
gi|62765910|gb|AAX99171.1| penicillin binding protein [Stre... 541 e-152
gi|62765952|gb|AAX99192.1| penicillin binding protein [Stre... 540 e-151
gi|62765946|gb|AAX99189.1| penicillin binding protein [Stre... 540 e-151
gi|62765974|gb|AAX99203.1| penicillin binding protein [Stre... 540 e-151
gi|62765950|gb|AAX99191.1| penicillin binding protein [Stre... 540 e-151
gi|62765976|gb|AAX99204.1| penicillin binding protein [Stre... 539 e-151
gi|62765902|gb|AAX99167.1| penicillin binding protein [Stre... 539 e-151
gi|62765918|gb|AAX99175.1| penicillin binding protein [Stre... 538 e-151
gi|154982280|gb|ABS89133.1| penicillin-binding protein 2X [... 538 e-151
gi|62765904|gb|AAX99168.1| penicillin binding protein [Stre... 538 e-151
gi|62765968|gb|AAX99200.1| penicillin binding protein [Stre... 537 e-151
gi|62765996|gb|AAX99214.1| penicillin binding protein [Stre... 537 e-150
gi|157057033|gb|ABV02555.1| penicillin-binding protein 2X [... 536 e-150
gi|62765930|gb|AAX99181.1| penicillin binding protein [Stre... 536 e-150
gi|62765970|gb|AAX99201.1| penicillin binding protein [Stre... 536 e-150
gi|62765906|gb|AAX99169.1| penicillin binding protein [Stre... 535 e-150
gi|62765926|gb|AAX99179.1| penicillin binding protein [Stre... 535 e-150
gi|62765934|gb|AAX99183.1| penicillin binding protein [Stre... 534 e-150
gi|62765966|gb|AAX99199.1| penicillin binding protein [Stre... 533 e-149
gi|62765938|gb|AAX99185.1| penicillin binding protein [Stre... 533 e-149
gi|62765962|gb|AAX99197.1| penicillin binding protein [Stre... 531 e-149
gi|157057031|gb|ABV02554.1| penicillin-binding protein 2X [... 529 e-148
gi|62765964|gb|AAX99198.1| penicillin binding protein [Stre... 528 e-148
gi|62765972|gb|AAX99202.1| penicillin binding protein [Stre... 524 e-147
gi|15672849|ref|NP_267023.1| penicillin-binding protein [La... 504 e-141
gi|125624477|ref|YP_001032960.1| penicillin-binding protein... 503 e-140
gi|116511691|ref|YP_808907.1| Cell division protein FtsI/pe... 497 e-138
gi|66096430|gb|AAY42867.1| penicillin-binding protein 2x [S... 493 e-137
gi|66096445|gb|AAY42868.1| penicillin-binding protein 2x [S... 490 e-136
gi|66096504|gb|AAY42872.1| penicillin-binding protein 2x [S... 490 e-136
gi|66096473|gb|AAY42870.1| penicillin-binding protein 2x [S... 489 e-136
gi|5566443|gb|AAD45394.1|AF167442_1 penicillin-binding prot... 488 e-136
gi|66096516|gb|AAY42873.1| penicillin-binding protein 2x [S... 487 e-135
gi|66096458|gb|AAY42869.1| penicillin-binding protein 2x [S... 486 e-135
gi|66096530|gb|AAY42874.1| penicillin-binding protein 2x [S... 486 e-135
gi|2149903|gb|AAC45633.1| penicillin-binding protein [Enter... 480 e-133
gi|29375573|ref|NP_814727.1| penicillin-binding protein C [... 479 e-133
gi|2222671|emb|CAA74232.1| pbp3s [Enterococcus hirae] 473 e-131
gi|69244716|ref|ZP_00602980.1| Peptidoglycan glycosyltransf... 469 e-130
gi|71011345|gb|AAZ17414.1| penicillin binding protein 2X [S... 461 e-128
gi|18920715|gb|AAL82400.1| penicillin-binding protein 2X [S... 432 e-119
gi|18920713|gb|AAL82399.1| penicillin-binding protein 2X [S... 431 e-118
gi|18920711|gb|AAL82398.1| penicillin-binding protein 2X [S... 429 e-118
gi|18920709|gb|AAL82397.1| penicillin-binding protein 2X [S... 428 e-118
gi|18920717|gb|AAL82401.1| penicillin-binding protein 2X [S... 425 e-117
gi|18920707|gb|AAL82396.1| penicillin-binding protein 2X [S... 424 e-116
gi|4519232|dbj|BAA75529.1| penicillin binding protein 2X [S... 405 e-111
gi|4519228|dbj|BAA75527.1| penicillin binding protein 2X [S... 397 e-108
gi|4519226|dbj|BAA75526.1| penicillin binding protein 2X [S... 396 e-108
gi|4519238|dbj|BAA75532.1| penicillin binding protein 2X [S... 392 e-107
gi|4519230|dbj|BAA75528.1| penicillin binding protein 2X [S... 391 e-107
gi|4519236|dbj|BAA75531.1| penicillin binding protein 2X [S... 390 e-106
gi|4519240|dbj|BAA75533.1| penicillin binding protein 2X [S... 390 e-106
gi|4519234|dbj|BAA75530.1| penicillin binding protein 2X [S... 389 e-106
gi|4519224|dbj|BAA75525.1| penisillin binding protein 2X [S... 389 e-106
gi|46798935|emb|CAG27314.1| penicillin-binding protein 2x [... 385 e-105
gi|46798941|emb|CAG27315.1| penicillin-binding protein 2x [... 384 e-104
gi|47021203|emb|CAG27776.1| penicillin-binding protein 2x [... 384 e-104
gi|47021199|emb|CAG27774.1| penicillin-binding protein 2x [... 383 e-104
gi|116334054|ref|YP_795581.1| Cell division protein FtsI/pe... 383 e-104
gi|46798924|emb|CAG27312.1| penicillin-binding protein 2x [... 382 e-104
gi|47021205|emb|CAG27777.1| penicillin-binding protein 2x [... 381 e-104
gi|47021197|emb|CAG27773.1| penicillin-binding protein 2x [... 380 e-103
gi|46798919|emb|CAG27311.1| penicillin-binding protein 2x [... 379 e-103
gi|46798912|emb|CAG27310.1| penicillin-binding protein 2x [... 378 e-103
gi|4519254|dbj|BAA75540.1| penicillin-binding protein 2x [S... 376 e-102
gi|90962028|ref|YP_535944.1| Penicillin binding protein 2B ... 376 e-102
gi|4519250|dbj|BAA75538.1| penicillin-binding protein 2x [S... 375 e-102
gi|60549987|gb|AAX24138.1| penicillin-binding protein 2X [S... 374 e-101
gi|4519244|dbj|BAA75535.1| penicillin-binding protein 2x [S... 374 e-101
gi|46798929|emb|CAG27313.1| penicillin-binding protein 2x [... 373 e-101
gi|56807573|ref|ZP_00365488.1| COG0768: Cell division prote... 372 e-101
gi|4519248|dbj|BAA75537.1| penicillin-binding protein 2x [S... 371 e-100
gi|4519242|dbj|BAA75534.1| penicillin-binding protein 2x [S... 369 e-100
gi|154997060|gb|ABS89208.1| Pbp2X [Streptococcus pneumoniae] 367 2e-99
gi|28378803|ref|NP_785695.1| penicillin binding protein 2B ... 367 2e-99
gi|116492950|ref|YP_804685.1| Cell division protein FtsI/pe... 363 2e-98
gi|4519216|dbj|BAA75521.1| penisillin binding protein 2X [S... 359 5e-97
gi|62183569|gb|AAX73225.1| penicillin-binding protein 2x [S... 358 7e-97
gi|62183579|gb|AAX73230.1| penicillin-binding protein 2x [S... 358 9e-97
gi|62183573|gb|AAX73227.1| penicillin-binding protein 2x [S... 358 1e-96
gi|4519220|dbj|BAA75523.1| penicillin binding protein 2X [S... 358 1e-96
gi|116494760|ref|YP_806494.1| Cell division protein FtsI/pe... 358 1e-96
gi|4519218|dbj|BAA75522.1| penisillin binding protein 2X [S... 358 1e-96
gi|4519222|dbj|BAA75524.1| penicillin bindin protein 2X [St... 357 1e-96
gi|154997066|gb|ABS89210.1| Pbp2X [Streptococcus pneumoniae] 357 2e-96
gi|62183571|gb|AAX73226.1| penicillin-binding protein 2x [S... 356 4e-96
gi|58337115|ref|YP_193700.1| penicillin-binding protein [La... 355 6e-96
gi|15277680|gb|AAK93961.1| penicillin-binding protein 2X [S... 354 1e-95
gi|81428359|ref|YP_395359.1| Bifunctional dimerisation/tran... 353 3e-95
gi|34597619|gb|AAQ77366.1| penicillin-binding protein 2X [S... 348 1e-93
gi|42518894|ref|NP_964824.1| penicillin-binding protein 2B ... 345 9e-93
gi|104773822|ref|YP_618802.1| Cell division protein FtsI [L... 344 2e-92
gi|34597615|gb|AAQ77364.1| penicillin-binding protein 2X [S... 343 2e-92
gi|34597613|gb|AAQ77363.1| penicillin-binding protein 2X [S... 343 2e-92
gi|34597611|gb|AAQ77362.1| penicillin-binding protein 2X [S... 343 3e-92
gi|47093591|ref|ZP_00231349.1| penicillin-binding protein [... 343 4e-92
gi|116513829|ref|YP_812735.1| Cell division protein FtsI/pe... 342 4e-92
gi|153203084|ref|ZP_01944466.1| hypothetical protein LMSG_0... 342 4e-92
gi|153167899|ref|ZP_01927969.1| hypothetical protein LMHG_0... 342 5e-92
gi|16804078|ref|NP_465563.1| hypothetical protein lmo2039 [... 342 6e-92
gi|47097271|ref|ZP_00234830.1| penicillin-binding protein [... 342 8e-92
gi|34597609|gb|AAQ77361.1| penicillin-binding protein 2X [S... 341 9e-92
gi|16801211|ref|NP_471479.1| pbpB [Listeria innocua Clip112... 341 1e-91
gi|153191562|ref|ZP_01938752.1| hypothetical protein LMPG_0... 341 1e-91
gi|116629842|ref|YP_815014.1| Cell division protein FtsI/pe... 340 3e-91
gi|116873469|ref|YP_850250.1| penicillin-binding protein [L... 339 4e-91
gi|148543821|ref|YP_001271191.1| Peptidoglycan glycosyltran... 339 4e-91
gi|34597617|gb|AAQ77365.1| penicillin-binding protein 2X [S... 339 4e-91
gi|46908275|ref|YP_014664.1| penicillin-binding protein [Li... 338 6e-91
gi|92089146|ref|ZP_01274098.1| Peptidoglycan glycosyltransf... 337 1e-90
gi|68160888|gb|AAY86890.1| lr1631 [Lactobacillus reuteri] 335 7e-90
gi|89099601|ref|ZP_01172476.1| penicillin-binding protein 2... 334 2e-89
gi|149181749|ref|ZP_01860241.1| pbpB [Bacillus sp. SG-1] >g... 327 2e-87
gi|126649731|ref|ZP_01721967.1| hypothetical protein BB1490... 325 1e-86
gi|154685935|ref|YP_001421096.1| PbpB [Bacillus amyloliquef... 318 6e-85
gi|124522375|ref|ZP_01696993.1| penicillin-binding protein,... 316 3e-84
gi|116618592|ref|YP_818963.1| Cell division protein FtsI/pe... 314 1e-83
gi|73662899|ref|YP_301680.1| penicillin-binding protein 1 [... 309 5e-82
gi|70726735|ref|YP_253649.1| penicillin-binding protein 1 [... 308 1e-81
gi|116491166|ref|YP_810710.1| Cell division protein FtsI/pe... 307 2e-81
gi|52080118|ref|YP_078909.1| penicillin-binding protein 2B ... 305 1e-80
gi|118587347|ref|ZP_01544773.1| penicillin-binding protein ... 304 1e-80
gi|89209139|ref|ZP_01187596.1| Peptidoglycan glycosyltransf... 294 2e-77
gi|57866680|ref|YP_188329.1| penicillin-binding protein 1 [... 292 6e-77
gi|23098919|ref|NP_692385.1| penicillin-binding protein 2B ... 292 7e-77
gi|21282793|ref|NP_645881.1| penicillin-binding protein 1 [... 291 9e-77
gi|57650293|ref|YP_186057.1| penicillin-binding protein 1 [... 291 1e-76
gi|15924171|ref|NP_371705.1| penicillin-binding protein 1 [... 291 1e-76
gi|75762008|ref|ZP_00741923.1| Division specific D,D-transp... 288 1e-75
gi|27467774|ref|NP_764411.1| penicillin-binding protein 1 [... 288 1e-75
gi|56419648|ref|YP_146966.1| penicillin-binding protein 2B ... 287 2e-75
gi|47565788|ref|ZP_00236827.1| penicillin-binding protein 1... 284 2e-74
gi|30022005|ref|NP_833636.1| Division specific D,D-transpep... 284 2e-74
gi|138894648|ref|YP_001125101.1| High molecular weight peni... 283 3e-74
gi|49478447|ref|YP_037978.1| penicillin-binding protein [Ba... 282 6e-74
gi|118479136|ref|YP_896287.1| penicillin-binding protein [B... 281 8e-74
gi|15615136|ref|NP_243439.1| penicillin-binding protein 2B ... 281 9e-74
gi|42783010|ref|NP_980257.1| penicillin-binding protein [Ba... 280 2e-73
gi|65321243|ref|ZP_00394202.1| COG0768: Cell division prote... 280 2e-73
gi|52141572|ref|YP_085257.1| penicillin-binding protein [Ba... 280 3e-73
gi|30263918|ref|NP_846295.1| penicillin-binding protein [Ba... 279 5e-73
gi|66096417|gb|AAY42866.1| penicillin-binding protein 2x [S... 278 7e-73
gi|118478032|ref|YP_895183.1| penicillin-binding protein, t... 278 8e-73
gi|16078580|ref|NP_389399.1| penicillin-binding protein 2B ... 277 2e-72
gi|30262633|ref|NP_845010.1| penicillin-binding protein [Ba... 277 2e-72
gi|42781738|ref|NP_978985.1| penicillin-binding protein [Ba... 276 4e-72
gi|66096488|gb|AAY42871.1| penicillin-binding protein 2x [S... 276 4e-72
gi|66096543|gb|AAY42875.1| penicillin-binding protein 2x [S... 276 4e-72
gi|47569611|ref|ZP_00240288.1| penicillin-binding protein 1... 276 5e-72
gi|47080175|gb|AAT10206.1| penicillin-binding protein 2X [S... 276 6e-72
gi|47080177|gb|AAT02262.2| penicillin-binding protein 2X [S... 275 7e-72
gi|52142849|ref|YP_083981.1| penicillin-binding protein, tr... 275 8e-72
gi|47080179|gb|AAT02264.2| penicillin-binding protein 2X [S... 275 1e-71
gi|47080185|gb|AAT02267.2| penicillin-binding protein 2X [S... 275 1e-71
gi|65319954|ref|ZP_00392913.1| COG0768: Cell division prote... 274 1e-71
gi|49477812|ref|YP_036757.1| penicillin-binding protein, tr... 274 1e-71
gi|47080227|gb|AAT10214.1| penicillin-binding protein 2X [S... 274 2e-71
gi|30020787|ref|NP_832418.1| Division specific D,D-transpep... 273 3e-71
gi|47080187|gb|AAT10207.1| penicillin-binding protein 2X [S... 273 3e-71
gi|47080221|gb|AAT10212.1| penicillin-binding protein 2X [S... 273 3e-71
gi|47080183|gb|AAT02266.2| penicillin-binding protein 2X [S... 273 4e-71
gi|47080199|gb|AAT02272.2| penicillin-binding protein 2X [S... 273 4e-71
gi|89209089|ref|ZP_01187552.1| Peptidoglycan glycosyltransf... 271 1e-70
gi|152976278|ref|YP_001375795.1| Peptidoglycan glycosyltran... 271 1e-70
gi|47080181|gb|AAT02265.2| penicillin-binding protein 2X [S... 271 2e-70
gi|68055472|ref|ZP_00539617.1| Peptidoglycan glycosyltransf... 269 6e-70
gi|56964127|ref|YP_175858.1| penicillin-binding protein 2B ... 266 3e-69
gi|56808160|ref|ZP_00365942.1| COG0768: Cell division prote... 255 8e-66
gi|77410105|ref|ZP_00786630.1| penicillin-binding protein 2... 253 3e-65
gi|12055041|emb|CAC20947.1| penicillin binding protein 2x [... 216 5e-54
gi|12055039|emb|CAC20946.1| penicillin binding protein 2x [... 215 8e-54
gi|12055053|emb|CAC20953.1| penicillin binding protein 2x [... 209 6e-52
gi|12055055|emb|CAC20954.1| penicillin binding protein 2x [... 208 9e-52
gi|12055043|emb|CAC20948.1| penicillin binding protein 2x [... 208 1e-51
gi|12055045|emb|CAC20949.1| penicillin binding protein 2x [... 207 2e-51
gi|12055051|emb|CAC20952.1| penicillin binding protein 2x [... 206 6e-51
gi|12055057|emb|CAC20955.1| penicillin binding protein 2x [... 205 8e-51
>gi|55821675|ref|YP_140117.1| penicillin binding protein 2X [Streptococcus thermophilus LMG
18311]
gi|55823595|ref|YP_142036.1| penicillin binding protein 2X [Streptococcus thermophilus CNRZ1066]
gi|55737660|gb|AAV61302.1| penicillin binding protein 2X [Streptococcus thermophilus LMG
18311]
gi|55739580|gb|AAV63221.1| penicillin binding protein 2X [Streptococcus thermophilus CNRZ1066]
Length = 755
Score = 1341 bits (3470), Expect = 0.0, Method: Composition-based stats.
Identities = 755/755 (100%), Positives = 755/755 (100%)
Query: 1 MNRLKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGV 60
MNRLKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGV
Sbjct: 1 MNRLKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGV 60
Query: 61 DLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQE 120
DLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQE
Sbjct: 61 DLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQE 120
Query: 121 SQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIK 180
SQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIK
Sbjct: 121 SQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIK 180
Query: 181 GMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAI 240
GMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAI
Sbjct: 181 GMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAI 240
Query: 241 YEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVN 300
YEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVN
Sbjct: 241 YEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVN 300
Query: 301 AKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFN 360
AKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFN
Sbjct: 301 AKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFN 360
Query: 361 PNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWS 420
PNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWS
Sbjct: 361 PNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWS 420
Query: 421 NYLSLYKFGIPTRFGMVGESSGIVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIM 480
NYLSLYKFGIPTRFGMVGESSGIVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIM
Sbjct: 421 NYLSLYKFGIPTRFGMVGESSGIVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIM 480
Query: 481 LEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGS 540
LEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGS
Sbjct: 481 LEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGS 540
Query: 541 PIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKT 600
PIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKT
Sbjct: 541 PIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKT 600
Query: 601 WNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQN 660
WNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQN
Sbjct: 601 WNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQN 660
Query: 661 LVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGI 720
LVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGI
Sbjct: 661 LVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGI 720
Query: 721 KITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
KITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD
Sbjct: 721 KITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
>gi|116628388|ref|YP_821007.1| Cell division protein FtsI/penicillin-binding protein 2
[Streptococcus thermophilus LMD-9]
gi|116101665|gb|ABJ66811.1| Cell division protein FtsI/penicillin-binding protein 2
[Streptococcus thermophilus LMD-9]
Length = 755
Score = 1329 bits (3440), Expect = 0.0, Method: Composition-based stats.
Identities = 747/755 (98%), Positives = 750/755 (99%)
Query: 1 MNRLKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGV 60
MNRLKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGV
Sbjct: 1 MNRLKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGV 60
Query: 61 DLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQE 120
DLSTQAAKSY TKT VAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQE
Sbjct: 61 DLSTQAAKSYKTKTTVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQE 120
Query: 121 SQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIK 180
SQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIK
Sbjct: 121 SQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIK 180
Query: 181 GMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAI 240
GMAFEATTSRMYPNG FASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAI
Sbjct: 181 GMAFEATTSRMYPNGIFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAI 240
Query: 241 YEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVN 300
YEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKG+NASATVVN
Sbjct: 241 YEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGVNASATVVN 300
Query: 301 AKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFN 360
AKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFN
Sbjct: 301 AKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFN 360
Query: 361 PNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWS 420
PNATYSNANGIKVGDVEINDWSINEGIS GRTMSFAQGFSYSSNVGMTMLEQAMGDKVWS
Sbjct: 361 PNATYSNANGIKVGDVEINDWSINEGISTGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWS 420
Query: 421 NYLSLYKFGIPTRFGMVGESSGIVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIM 480
NYLSLYKFGIPTRFGMVGESSGIVS+NSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIM
Sbjct: 421 NYLSLYKFGIPTRFGMVGESSGIVSRNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIM 480
Query: 481 LEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGS 540
LEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGS
Sbjct: 481 LEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGS 540
Query: 541 PIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKT 600
PIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKT
Sbjct: 541 PIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKT 600
Query: 601 WNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQN 660
WNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQN
Sbjct: 601 WNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQN 660
Query: 661 LVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGI 720
LVHPIVLGVGNKIEKVSVDAKE+IKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGI
Sbjct: 661 LVHPIVLGVGNKIEKVSVDAKEDIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGI 720
Query: 721 KITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
KITYKGGKSGTVTKQSVAAGEALSK KKITITLGD
Sbjct: 721 KITYKGGKSGTVTKQSVAAGEALSKIKKITITLGD 755
>gi|24378943|ref|NP_720898.1| putative penicillin-binding protein 2X [Streptococcus mutans UA159]
gi|24376829|gb|AAN58204.1|AE014891_8 putative penicillin-binding protein 2X [Streptococcus mutans UA159]
Length = 749
Score = 826 bits (2134), Expect = 0.0, Method: Composition-based stats.
Identities = 451/753 (59%), Positives = 569/753 (75%), Gaps = 5/753 (0%)
Query: 4 LKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLS 63
+K K FL+YVV DRR P +NR+ VGQNLM+LS+FIF VFI+NF++IIGTD KFGV+LS
Sbjct: 1 MKNFKKKFLDYVVGDRRVPRENRERVGQNLMILSVFIFCVFIVNFIIIIGTDRKFGVNLS 60
Query: 64 TQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQF 123
A+ Y T V AKRGTIYDRNGN +AEDST+Y+IYA++ SYVS + EKLYVQ SQ+
Sbjct: 61 KGASSVYQTVQKVQAKRGTIYDRNGNPIAEDSTTYNIYAVIDKSYVSTSGEKLYVQPSQY 120
Query: 124 DKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMA 183
DKVADIL LG++K Y AQL+ K QVSFG KG ITY D+ K KDA IKG+A
Sbjct: 121 DKVADILNQHLGMEKDYVTAQLKQKKLTQVSFGSKGSNITYGTMTDVTKALKDAKIKGVA 180
Query: 184 FEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEK 243
F + RMYPNGTFAS+F+G A+ EN KDGS SL+G TG+E SL+ +L+G DG+ Y+K
Sbjct: 181 FTTSPGRMYPNGTFASQFIGLAQIKEN-KDGSKSLVGATGMEASLDKILSGKDGQVTYQK 239
Query: 244 DKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKT 303
DK+GNTLLG T K+A DGK++YTTLSAP+QT+LETQMD F + KG ASAT+VNAKT
Sbjct: 240 DKNGNTLLGAATTVKKAQDGKDVYTTLSAPIQTYLETQMDAFQSKAKGAQASATLVNAKT 299
Query: 304 GEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNA 363
GEILAT+QRP++NSDT EG K + W N LY+ YEPGSTMKVMLL+AAI+ G FNPN
Sbjct: 300 GEILATSQRPSFNSDTKEGLDSKDFSWQNALYQTNYEPGSTMKVMLLAAAIDEGVFNPNE 359
Query: 364 TYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYL 423
TY+NA+ + + D I DWS+NEGIS+G +SFAQGF+YSSNVGMT+LEQ MG+ W NYL
Sbjct: 360 TYNNAS-LSIADATIKDWSVNEGISQGGYLSFAQGFAYSSNVGMTLLEQKMGNDNWLNYL 418
Query: 424 SLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLE 482
+ Y+FG+PTRFGM E+SG++ S N V IA S+FGQGI VTQ QMLRAFT++SN+G+MLE
Sbjct: 419 NKYRFGLPTRFGMGSEASGLLPSDNMVTIAMSAFGQGIGVTQTQMLRAFTSVSNDGVMLE 478
Query: 483 PQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPI 542
PQFI ++ D G+ RTAKKE G PVS AA +TR YM++VGTDP +GTLY+ S G P+
Sbjct: 479 PQFITKIYDPKTGSSRTAKKEEAGNPVSADAAKQTRQYMVTVGTDPNYGTLYSASLGGPV 538
Query: 543 IQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWN 602
I+VGN VAVKSGTAQ+ Y G+N+ + SVVAMVPS++P+++MYVT+Q+P++++
Sbjct: 539 IKVGNQSVAVKSGTAQIASGDGSGYLSGSNDYIYSVVAMVPSDNPDFLMYVTLQQPESFS 598
Query: 603 NNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLV 662
+F+ VVNPVLEEA M TL + + + ++T Y ++IGK PG TA+ LRQNLV
Sbjct: 599 VSFWQDVVNPVLEEATLMKDTLLAPIE--TPEDQQTKYYLPNVIGKNPGNTADDLRQNLV 656
Query: 663 HPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKI 722
HPIVLG GNKI K SV N+K N+Q+L++T+ F +PDMYGW+KKNV+ F W GIK+
Sbjct: 657 HPIVLGTGNKIIKTSVSVGSNLKENQQVLLLTSHFDTMPDMYGWSKKNVKKFEDWTGIKV 716
Query: 723 TYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
T+KG KSG VT+QSV G L KKI ITLG+
Sbjct: 717 TFKGKKSGKVTEQSVKVGSKLKNLKKIRITLGE 749
>gi|50914759|ref|YP_060731.1| Division specific D,D-transpeptidase [Streptococcus pyogenes
MGAS10394]
gi|50903833|gb|AAT87548.1| Division specific D,D-transpeptidase; FtsI [Streptococcus pyogenes
MGAS10394]
Length = 751
Score = 801 bits (2070), Expect = 0.0, Method: Composition-based stats.
Identities = 449/754 (59%), Positives = 565/754 (74%), Gaps = 5/754 (0%)
Query: 4 LKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLS 63
+KK + L+YVVRDRR P +NR VGQN+M+L+IFIFF+FIINF++IIGTD KFGV LS
Sbjct: 1 MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIINFMIIIGTDQKFGVSLS 60
Query: 64 TQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQF 123
A K Y + AKRGTIYDRNG +A DST+YSIYAI+ S+VS + EKLYVQ SQ+
Sbjct: 61 EGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILDKSFVSASDEKLYVQPSQY 120
Query: 124 DKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMA 183
+ VADILK LG+KK+ + QL+ KG +QVSFG G GI+YS ++K +DA IKG+A
Sbjct: 121 ETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGISYSTMSTIQKAMEDAKIKGIA 180
Query: 184 FEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEK 243
F + RMYPNGTFASEF+G A E+KK G SL+G+TGLE S + +L+G DG Y+K
Sbjct: 181 FTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGKTGLEASFDKILSGQDGVITYQK 240
Query: 244 DKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKT 303
D++G TLLGT K+AIDGK+IYTTLS P+QTFLETQMD F ++ G ASAT+VNAKT
Sbjct: 241 DRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQLASATLVNAKT 300
Query: 304 GEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNA 363
GEILATTQRPTYN+DTL+G Y W + L++ +EPGSTMKVM L+AAI++ FNPN
Sbjct: 301 GEILATTQRPTYNADTLKGLENTNYKWYSALHQGNFEPGSTMKVMTLAAAIDDKVFNPNE 360
Query: 364 TYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYL 423
T+SNANG+ + D I DWSINEGIS G+ M++AQGF++SSNVGMT LEQ MG+ W NYL
Sbjct: 361 TFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFAFSSNVGMTKLEQKMGNAKWMNYL 420
Query: 424 SLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLE 482
+ ++FG PTRFG+ E +GI S N V A S+FGQGISVTQ+QMLRAFTAISNNG MLE
Sbjct: 421 TKFRFGFPTRFGLKDEDAGIFPSDNIVTQAMSAFGQGISVTQIQMLRAFTAISNNGEMLE 480
Query: 483 PQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPI 542
PQFI Q+ D N + RTA KEV+GKPVSK+AASETR YMI VGTDPEFGTLY+K+ G PI
Sbjct: 481 PQFISQIYDPNTASFRTANKEVVGKPVSKKAASETRQYMIGVGTDPEFGTLYSKTFG-PI 539
Query: 543 IQVGNNDVAVKSGTAQVPDEKTGTYK-VGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTW 601
I+VG+ VAVKSGTAQ+ E Y+ G + SVVAMVP++ P+++MYVT+ +P+ +
Sbjct: 540 IKVGDLPVAVKSGTAQIGSEDGSGYQDGGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHF 599
Query: 602 NNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNL 661
F+ VVNPVLEEA M TL V S +T+Y+ + +GK PGET++ LR+NL
Sbjct: 600 GPLFWQDVVNPVLEEAYLMQDTLTKPVV--SDANRQTTYKLPNFVGKNPGETSSELRRNL 657
Query: 662 VHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIK 721
V P+VLG G+KI+KVS + + + N+Q+LI+++ F E+PDMYGWTK NVETFAKW GI
Sbjct: 658 VQPVVLGTGSKIKKVSHQSGQTLTENQQVLILSDRFVEVPDMYGWTKSNVETFAKWTGID 717
Query: 722 ITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
I++KG SG V KQSV G++L K KK+TITLGD
Sbjct: 718 ISFKGTDSGRVMKQSVDVGKSLKKIKKMTITLGD 751
>gi|28895373|ref|NP_801723.1| putative penicillin binding protein 2X [Streptococcus pyogenes
SSI-1]
gi|28810619|dbj|BAC63556.1| putative penicillin binding protein 2X [Streptococcus pyogenes
SSI-1]
Length = 751
Score = 801 bits (2068), Expect = 0.0, Method: Composition-based stats.
Identities = 447/754 (59%), Positives = 564/754 (74%), Gaps = 5/754 (0%)
Query: 4 LKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLS 63
+KK + L+YVVRDRR P +NR VGQN+M+L+IFIFF+FIINF++IIGTD KFGV LS
Sbjct: 1 MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIINFMIIIGTDQKFGVSLS 60
Query: 64 TQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQF 123
A K Y + AKRGTIYDRNG +A DST+YSIYAI+ S+VS + EKLYVQ SQ+
Sbjct: 61 EGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILDKSFVSASDEKLYVQPSQY 120
Query: 124 DKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMA 183
+ VADILK LG+KK+ + QL+ KG +QVSFG G GI+YS ++K +DA IKG+A
Sbjct: 121 ETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGISYSTMSTIQKAMEDAKIKGIA 180
Query: 184 FEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEK 243
F + RMYPNGTFASEF+G A E+KK G SL+G+TGLE S + +L+G DG Y+K
Sbjct: 181 FTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGKTGLEASFDKILSGQDGVITYQK 240
Query: 244 DKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKT 303
D++G TLLGT K+AIDGK+IYTTLS P+QTFLETQMD F ++ G ASAT+VNAKT
Sbjct: 241 DRNGATLLGTGKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQLASATLVNAKT 300
Query: 304 GEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNA 363
GEILATTQRPTYN+DTL+G Y W + L++ +EPGSTMKVM L+AAI++ FNPN
Sbjct: 301 GEILATTQRPTYNADTLKGLENTNYKWYSALHQGNFEPGSTMKVMTLAAAIDDKVFNPNE 360
Query: 364 TYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYL 423
T+SNANG+ + D I DWSINEGIS G+ M++AQGF++SSNVGMT LEQ MG+ W NYL
Sbjct: 361 TFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFAFSSNVGMTKLEQKMGNAKWMNYL 420
Query: 424 SLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLE 482
+ ++FG PTRFG+ E +GI S N V A S+FGQGISVTQ+QMLRAFTAISNNG MLE
Sbjct: 421 TKFRFGFPTRFGLKDEDAGIFPSDNIVTQAMSAFGQGISVTQIQMLRAFTAISNNGEMLE 480
Query: 483 PQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPI 542
PQFI Q+ D N + RTA KE++GKPVSK+AASETR YMI VGTDPEFGTLY+K+ G PI
Sbjct: 481 PQFISQIYDPNTASFRTANKEIVGKPVSKKAASETRQYMIGVGTDPEFGTLYSKTFG-PI 539
Query: 543 IQVGNNDVAVKSGTAQVPDEKTGTYK-VGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTW 601
I+VG+ VAVKSGTAQ+ E Y+ G + SVVAMVP++ P+++MYVT+ +P+ +
Sbjct: 540 IKVGDLPVAVKSGTAQIGSEDGSGYQDGGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHF 599
Query: 602 NNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNL 661
F+ VVNPVLEEA M TL V S +T+Y+ + +GK PGET++ LR+NL
Sbjct: 600 GPLFWQDVVNPVLEEAYLMQDTLTKPVV--SDANRQTTYKLPNFVGKNPGETSSELRRNL 657
Query: 662 VHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIK 721
V P+VLG G+KI+KVS + + N+Q+LI+++ F E+PDMYGWTK NV+TFAKW GI
Sbjct: 658 VQPVVLGTGSKIKKVSHQPGQTLTENQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGID 717
Query: 722 ITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
I++KG SG V KQSV G++L K KK+TITLGD
Sbjct: 718 ISFKGTDSGRVMKQSVDVGKSLKKIKKMTITLGD 751
>gi|15675531|ref|NP_269705.1| putative penicillin binding protein 2X [Streptococcus pyogenes M1
GAS]
gi|19746581|ref|NP_607717.1| putative penicillin binding protein [Streptococcus pyogenes
MGAS8232]
gi|71904070|ref|YP_280873.1| cell division protein ftsI [Streptococcus pyogenes MGAS6180]
gi|71911179|ref|YP_282729.1| division specific D,D-transpeptidase/cell division protein ftsI
[Streptococcus pyogenes MGAS5005]
gi|94990993|ref|YP_599093.1| Division specific D,D-transpeptidase / Cell division protein ftsI
[Streptococcus pyogenes MGAS10270]
gi|94992886|ref|YP_600985.1| Division specific D,D-transpeptidase / Cell division protein ftsI
[Streptococcus pyogenes MGAS2096]
gi|94994872|ref|YP_602970.1| Division specific D,D-transpeptidase / Cell division protein ftsI
[Streptococcus pyogenes MGAS10750]
gi|139473297|ref|YP_001128012.1| putative penicillin binding protein 2x [Streptococcus pyogenes str.
Manfredo]
gi|13622731|gb|AAK34426.1| putative penicillin binding protein 2X [Streptococcus pyogenes M1
GAS]
gi|19748796|gb|AAL98216.1| putative penicillin binding protein [Streptococcus pyogenes
MGAS8232]
gi|71803165|gb|AAX72518.1| division specific D,D-transpeptidase [Streptococcus pyogenes
MGAS6180]
gi|71853961|gb|AAZ51984.1| division specific D,D-transpeptidase/cell division protein ftsI
[Streptococcus pyogenes MGAS5005]
gi|94544501|gb|ABF34549.1| Division specific D,D-transpeptidase / Cell division protein ftsI
[Streptococcus pyogenes MGAS10270]
gi|94546394|gb|ABF36441.1| Division specific D,D-transpeptidase / Cell division protein ftsI
[Streptococcus pyogenes MGAS2096]
gi|94548380|gb|ABF38426.1| Division specific D,D-transpeptidase / Cell division protein ftsI
[Streptococcus pyogenes MGAS10750]
gi|134271543|emb|CAM29767.1| putative penicillin binding protein 2x [Streptococcus pyogenes str.
Manfredo]
Length = 751
Score = 800 bits (2066), Expect = 0.0, Method: Composition-based stats.
Identities = 447/754 (59%), Positives = 564/754 (74%), Gaps = 5/754 (0%)
Query: 4 LKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLS 63
+KK + L+YVVRDRR P +NR VGQN+M+L+IFIFF+FIINF++IIGTD KFGV LS
Sbjct: 1 MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIINFMIIIGTDQKFGVSLS 60
Query: 64 TQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQF 123
A K Y + AKRGTIYDRNG +A DST+YSIYAI+ S+VS + EKLYVQ SQ+
Sbjct: 61 EGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILDKSFVSASDEKLYVQPSQY 120
Query: 124 DKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMA 183
+ VADILK LG+KK+ + QL+ KG +QVSFG G GI+YS ++K +DA IKG+A
Sbjct: 121 ETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGISYSTMSTIQKAMEDAKIKGIA 180
Query: 184 FEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEK 243
F + RMYPNGTFASEF+G A E+KK G SL+G+TGLE S + +L+G DG Y+K
Sbjct: 181 FTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGKTGLEASFDKILSGQDGVITYQK 240
Query: 244 DKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKT 303
D++G TLLGT K+AIDGK+IYTTLS P+QTFLETQMD F ++ G ASAT+VNAKT
Sbjct: 241 DRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQLASATLVNAKT 300
Query: 304 GEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNA 363
GEILATTQRPTYN+DTL+G Y W + L++ +EPGSTMKVM L+AAI++ FNPN
Sbjct: 301 GEILATTQRPTYNADTLKGLENTNYKWYSALHQGNFEPGSTMKVMTLAAAIDDKVFNPNE 360
Query: 364 TYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYL 423
T+SNANG+ + D I DWSINEGIS G+ M++AQGF++SSNVGMT LEQ MG+ W NYL
Sbjct: 361 TFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFAFSSNVGMTKLEQKMGNAKWMNYL 420
Query: 424 SLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLE 482
+ ++FG PTRFG+ E +GI S N V A S+FGQGISVTQ+QMLRAFTAISNNG MLE
Sbjct: 421 TKFRFGFPTRFGLKDEDAGIFPSDNIVTQAMSAFGQGISVTQIQMLRAFTAISNNGEMLE 480
Query: 483 PQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPI 542
PQFI Q+ D N + RTA KE++GKPVSK+AASETR YMI VGTDPEFGTLY+K+ G PI
Sbjct: 481 PQFISQIYDPNTASFRTANKEIVGKPVSKKAASETRQYMIGVGTDPEFGTLYSKTFG-PI 539
Query: 543 IQVGNNDVAVKSGTAQVPDEKTGTYK-VGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTW 601
I+VG+ VAVKSGTAQ+ E Y+ G + SVVAMVP++ P+++MYVT+ +P+ +
Sbjct: 540 IKVGDLPVAVKSGTAQIGSEDGSGYQDGGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHF 599
Query: 602 NNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNL 661
F+ VVNPVLEEA M TL V S +T+Y+ + +GK PGET++ LR+NL
Sbjct: 600 GPLFWQDVVNPVLEEAYLMQDTLTKPVV--SDANRQTTYKLPNFVGKNPGETSSELRRNL 657
Query: 662 VHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIK 721
V P+VLG G+KI+KVS + + N+Q+LI+++ F E+PDMYGWTK NV+TFAKW GI
Sbjct: 658 VQPVVLGTGSKIKKVSHQPGQTLTENQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGID 717
Query: 722 ITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
I++KG SG V KQSV G++L K KK+TITLGD
Sbjct: 718 ISFKGTDSGRVMKQSVDVGKSLKKIKKMTITLGD 751
>gi|94988993|ref|YP_597094.1| cell division protein ftsI [Streptococcus pyogenes MGAS9429]
gi|94542501|gb|ABF32550.1| division specific D,D-transpeptidase [Streptococcus pyogenes
MGAS9429]
Length = 751
Score = 797 bits (2059), Expect = 0.0, Method: Composition-based stats.
Identities = 446/754 (59%), Positives = 563/754 (74%), Gaps = 5/754 (0%)
Query: 4 LKKLKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLS 63
+KK + L+YVVRDRR P +NR VGQN+M+L+IFIFF+FIINF++IIGTD KFGV LS
Sbjct: 1 MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIINFMIIIGTDQKFGVSLS 60
Query: 64 TQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQF 123
A K Y + AKRGTIYDRNG +A DST+YSIYAI+ S+VS + EKLYVQ SQ+
Sbjct: 61 EGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILDKSFVSASDEKLYVQPSQY 120
Query: 124 DKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMA 183
+ VADILK LG+KK+ + QL+ KG +QVSFG G GI+YS ++K +DA IKG+A
Sbjct: 121 ETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGISYSTMSTIQKAMEDAKIKGIA 180
Query: 184 FEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEK 243
F + RMYPNGTFASEF+G A E+KK G SL+G+TGLE S + +L+G DG Y+K
Sbjct: 181 FTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGKTGLEASFDKILSGQDGVITYQK 240
Query: 244 DKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKT 303
D++G TLLGT K+AIDGK+IYTTLS P+QTFLETQMD F ++ G ASAT+VNAKT
Sbjct: 241 DRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQLASATLVNAKT 300
Query: 304 GEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNA 363
GEILATTQRPTYN+DTL+G Y W + L++ +EPGSTMKVM L+AAI++ FNPN
Sbjct: 301 GEILATTQRPTYNADTLKGLENTNYKWYSALHQGNFEPGSTMKVMTLAAAIDDKVFNPNE 360
Query: 364 TYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYL 423
T+SNANG+ + D I DWSINEGIS G+ M++AQGF++SSNV MT LEQ MG+ W NYL
Sbjct: 361 TFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFAFSSNVEMTKLEQKMGNAKWMNYL 420
Query: 424 SLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLE 482
+ ++FG PTRFG+ E +GI S N V A S+FGQGISVTQ+QMLRAFTAISNNG MLE
Sbjct: 421 TKFRFGFPTRFGLKDEDAGIFPSDNIVTQAMSAFGQGISVTQIQMLRAFTAISNNGEMLE 480
Query: 483 PQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPI 542
PQFI Q+ D N + RTA KE++GKPVSK+AASETR YMI VGTDPEFGTLY+K+ G PI
Sbjct: 481 PQFISQIYDPNTASFRTANKEIVGKPVSKKAASETRQYMIGVGTDPEFGTLYSKTFG-PI 539
Query: 543 IQVGNNDVAVKSGTAQVPDEKTGTYK-VGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTW 601
I+VG+ VAVKSGTAQ+ E Y+ G + SVVAMVP++ P+++MYVT+ +P+ +
Sbjct: 540 IKVGDLPVAVKSGTAQIGSEDGSGYQDGGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHF 599
Query: 602 NNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNL 661
F+ VVNPVLEEA M TL V S +T+Y+ + +GK PGET++ LR+NL
Sbjct: 600 GPLFWQDVVNPVLEEAYLMQDTLTKPVV--SDANRQTTYKLPNFVGKNPGETSSELRRNL 657
Query: 662 VHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIK 721
V P+VLG G+KI+KVS + + N+Q+LI+++ F E+PDMYGWTK NV+TFAKW GI
Sbjct: 658 VQPVVLGTGSKIKKVSHQPGQTLTENQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGID 717
Query: 722 ITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
I++KG SG V KQSV G++L K KK+TITLGD
Sbjct: 718 ISFKGTDSGRVMKQSVDVGKSLKKIKKMTITLGD 751
>gi|21910937|ref|NP_665205.1| putative penicillin binding protein 2X [Streptococcus pyogenes
MGAS315]
gi|21905144|gb|AAM80008.1| putative penicillin binding protein 2X [Streptococcus pyogenes
MGAS315]
Length = 722
Score = 766 bits (1979), Expect = 0.0, Method: Composition-based stats.
Identities = 416/705 (59%), Positives = 523/705 (74%), Gaps = 5/705 (0%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GTD KFGV LS A K Y + AKRGTIYDRNG +A DST+YSIYAI+ S+VS +
Sbjct: 21 GTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILDKSFVSAS 80
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
EKLYVQ SQ++ VADILK LG+KK+ + QL+ KG +QVSFG G GI+YS ++K
Sbjct: 81 DEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGISYSTMSTIQK 140
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
+DA IKG+AF + RMYPNGTFASEF+G A E+KK G SL+G+TGLE S + +L
Sbjct: 141 AMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGKTGLEASFDKIL 200
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
+G DG Y+KD++G TLLGT K+AIDGK+IYTTLS P+QTFLETQMD F ++ G
Sbjct: 201 SGQDGVITYQKDRNGATLLGTGKTVKKAIDGKDIYTTLSEPIQTFLETQMDVFQAKSNGQ 260
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
ASAT+VNAKTGEILATTQRPTYN+DTL+G Y W + L++ +EPGSTMKVM L+A
Sbjct: 261 LASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQGNFEPGSTMKVMTLAA 320
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
AI++ FNPN T+SNANG+ + D I DWSINEGIS G+ M++AQGF++SSNVGMT LEQ
Sbjct: 321 AIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNYAQGFAFSSNVGMTKLEQ 380
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAF 471
MG+ W NYL+ ++FG PTRFG+ E +GI S N V A S+FGQGISVTQ+QMLRAF
Sbjct: 381 KMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQAMSAFGQGISVTQIQMLRAF 440
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAISNNG MLEPQFI Q+ D N + RTA KE++GKPVSK+AASETR YMI VGTDPEFG
Sbjct: 441 TAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVSKKAASETRQYMIGVGTDPEFG 500
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYK-VGTNETLNSVVAMVPSEDPEYI 590
TLY+K+ G PII+VG+ VAVKSGTAQ+ E Y+ G + SVVAMVP++ P+++
Sbjct: 501 TLYSKTFG-PIIKVGDLPVAVKSGTAQIGSEDGSGYQDGGLTNYVYSVVAMVPADKPDFL 559
Query: 591 MYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTP 650
MYVT+ +P+ + F+ VVNPVLEEA M TL V S +T+Y+ + +GK P
Sbjct: 560 MYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTKPVV--SDANRQTTYKLPNFVGKNP 617
Query: 651 GETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKN 710
GET++ LR+NLV P+VLG G+KI+KVS + + N+Q+LI+++ F E+PDMYGWTK N
Sbjct: 618 GETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTENQQVLILSDRFVEVPDMYGWTKSN 677
Query: 711 VETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
V+TFAKW GI I++KG SG V KQSV G++L K KK+TITLGD
Sbjct: 678 VKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLKKIKKMTITLGD 722
>gi|77408178|ref|ZP_00784923.1| penicillin-binding protein 2X [Streptococcus agalactiae COH1]
gi|77173193|gb|EAO76317.1| penicillin-binding protein 2X [Streptococcus agalactiae COH1]
Length = 752
Score = 756 bits (1951), Expect = 0.0, Method: Composition-based stats.
Identities = 442/759 (58%), Positives = 567/759 (74%), Gaps = 11/759 (1%)
Query: 1 MNRLKKLKHLFLNYVV--RDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKF 58
M KKLK +FL+YV+ RDRR P +NR+ VGQNLM+L+IF+FF+FIINFV+I+GTDSKF
Sbjct: 1 MTFFKKLKKIFLDYVIHIRDRRSPQKNRERVGQNLMILTIFLFFIFIINFVIIVGTDSKF 60
Query: 59 GVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYV 118
GV+LS +A K Y V AKRGTIYDRNGN +AED+T+YS+YAI+S +Y + T +KLYV
Sbjct: 61 GVNLSKEAKKVYQQSMTVQAKRGTIYDRNGNPIAEDATTYSLYAIISKNYTTATGQKLYV 120
Query: 119 QESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAG 178
Q SQ++KVA IL++KLG+KK+ L QL K +QVSFG G G++Y+ D++KT + +
Sbjct: 121 QPSQYEKVASILENKLGMKKNLVLKQLNQKKLFQVSFGSSGSGLSYTKMADIKKTMEKSD 180
Query: 179 IKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGE 238
IKG+ F + R+YPNG FAS+F+G P ++ DG L+G TGLE +LN +L+GTDG+
Sbjct: 181 IKGIGFSTSPGRIYPNGIFASQFIGFTLP-QDDGDGK-KLVGNTGLEAALNKVLSGTDGK 238
Query: 239 AIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATV 298
YEKD+ GN LLGT T + A++GK+IYTTLS P+QT LETQMD F E+TKG ASATV
Sbjct: 239 VTYEKDRSGNVLLGTATTERRAVNGKDIYTTLSEPIQTVLETQMDVFAEKTKGKFASATV 298
Query: 299 VNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR-LYEAQYEPGSTMKVMLLSAAINNG 357
VNAKTGEILAT+QRPTYN TL+G KK N LY+ +EPGSTMKVM L++AI++
Sbjct: 299 VNAKTGEILATSQRPTYNPSTLKGYDKKNLGTYNTLLYDNFFEPGSTMKVMTLASAIDSK 358
Query: 358 SFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDK 417
FN Y++A K+ D I DW +NEG+S G M+F QGF++SSNVGM LEQ MG
Sbjct: 359 HFNSTEVYNSAQ-YKIADAVIRDWDVNEGLSSGSYMTFPQGFAHSSNVGMVTLEQKMGRD 417
Query: 418 VWSNYLSLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAFTAISN 476
W NYLS +KFG PTRFGM+ ES G+ S N V IA SSFGQGI VTQVQMLRAFT+ISN
Sbjct: 418 KWLNYLSKFKFGYPTRFGMLHESGGLFPSDNEVTIAMSSFGQGIGVTQVQMLRAFTSISN 477
Query: 477 NGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNK 536
+G+ML+PQFI + D N GT RTA+KEV+GKPVSK+AAS+TR+YM++VGTDP +GTLY
Sbjct: 478 DGVMLQPQFISSIYDPNTGTSRTARKEVVGKPVSKEAASKTRDYMVTVGTDPYYGTLY-- 535
Query: 537 SEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQ 596
+ G+P+IQVGN VAVKSGTAQ+ E G Y G N+T+NSVVAMVPSE+P++IMYVT+Q
Sbjct: 536 AAGAPVIQVGNQSVAVKSGTAQIAQEGGGGYLQGKNDTINSVVAMVPSENPDFIMYVTIQ 595
Query: 597 EPKTWNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANT 656
+P+ ++ F+ VVNPVLE+A +M T+ V S +T Y+ I+G+ PG A
Sbjct: 596 QPEKFSITFWKDVVNPVLEQATAMKETILKPVLNDS--EHQTKYKLSKIVGENPGHVAEE 653
Query: 657 LRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAK 716
LR+NLV PI+LG G+K+ KVS N+ NEQ+L++TN+ TELPDMYGW+K NVE FAK
Sbjct: 654 LRRNLVQPIILGNGSKVSKVSKRPGANLAENEQLLVLTNKLTELPDMYGWSKANVEQFAK 713
Query: 717 WKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
W GIK+TYKG SG V KQS+ G++++K KKI IT+GD
Sbjct: 714 WTGIKVTYKGSTSGKVRKQSIDVGKSINKIKKIKITIGD 752
>gi|22536471|ref|NP_687322.1| penicillin-binding protein 2X [Streptococcus agalactiae 2603V/R]
gi|76798780|ref|ZP_00780995.1| penicillin-binding protein 2X [Streptococcus agalactiae 18RS21]
gi|77404977|ref|ZP_00782078.1| penicillin-binding protein 2X [Streptococcus agalactiae H36B]
gi|77410588|ref|ZP_00786948.1| penicillin-binding protein 2X [Streptococcus agalactiae CJB111]
gi|22533301|gb|AAM99194.1|AE014204_12 penicillin-binding protein 2X [Streptococcus agalactiae 2603V/R]
gi|76585864|gb|EAO62407.1| penicillin-binding protein 2X [Streptococcus agalactiae 18RS21]
gi|77163303|gb|EAO74254.1| penicillin-binding protein 2X [Streptococcus agalactiae CJB111]
gi|77176416|gb|EAO79184.1| penicillin-binding protein 2X [Streptococcus agalactiae H36B]
Length = 752
Score = 754 bits (1946), Expect = 0.0, Method: Composition-based stats.
Identities = 442/760 (58%), Positives = 569/760 (74%), Gaps = 13/760 (1%)
Query: 1 MNRLKKLKHLFLNYVV--RDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKF 58
M KKLK +FL+YV+ RDRR P +NR+ VGQNLM+L+IF+FF+FIINFV+I+GTDSKF
Sbjct: 1 MTFFKKLKKIFLDYVIHIRDRRSPQKNRERVGQNLMILTIFLFFIFIINFVIIVGTDSKF 60
Query: 59 GVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYV 118
GV+LS +A K Y V AKRGTIYDRNGN +AED+T+YS+YAI+S +Y + T +KLYV
Sbjct: 61 GVNLSKEAKKVYQQSMTVQAKRGTIYDRNGNPIAEDATTYSLYAIISKNYTTATGQKLYV 120
Query: 119 QESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAG 178
Q SQ++KVA IL++KLG+KK+ L QL K +QVSFG G G++Y+ D++KT + +
Sbjct: 121 QPSQYEKVASILENKLGMKKNLVLKQLNQKKLFQVSFGSSGSGLSYTKMADIKKTMEKSD 180
Query: 179 IKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGE 238
IKG+ F + R+YPNG FAS+F+G P ++ DG L+G TGLE +LN +L+GTDG+
Sbjct: 181 IKGIGFSTSPGRIYPNGIFASQFIGFTLP-QDDGDGK-KLVGNTGLEAALNKVLSGTDGK 238
Query: 239 AIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATV 298
YEKD+ GN LLGT T + A++GK+IYTTLS P+QT LETQMD F E+TKG ASATV
Sbjct: 239 VTYEKDRSGNVLLGTATTERRAVNGKDIYTTLSEPIQTVLETQMDVFAEKTKGKFASATV 298
Query: 299 VNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR-LYEAQYEPGSTMKVMLLSAAINNG 357
VNAKTGEILAT+QRPTYN TL+G KK N LY+ +EPGSTMKVM L++AI++
Sbjct: 299 VNAKTGEILATSQRPTYNPSTLKGYDKKNLGTYNTLLYDNFFEPGSTMKVMTLASAIDSK 358
Query: 358 SFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDK 417
FN Y++A K+ D I DW +NEG+S G M+F QGF++SSNVGM LEQ MG
Sbjct: 359 HFNSTEVYNSAQ-YKIADAIIRDWDVNEGLSSGSYMTFPQGFAHSSNVGMVTLEQKMGRD 417
Query: 418 VWSNYLSLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAFTAISN 476
W NYLS +KFG PTRFGM+ ES G+ S N V IA SSFGQGI VTQVQMLRAFT+ISN
Sbjct: 418 KWLNYLSKFKFGYPTRFGMLHESGGLFPSDNEVTIAMSSFGQGIGVTQVQMLRAFTSISN 477
Query: 477 NGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNK 536
+G+ML+PQFI + D N GT RTA+KEV+GKPVSK+AAS+TR+YM++VGTDP +GTLY
Sbjct: 478 DGVMLQPQFISSIYDPNTGTSRTARKEVVGKPVSKEAASKTRDYMVTVGTDPYYGTLY-- 535
Query: 537 SEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQ 596
+ G+P+IQVGN VAVKSGTAQ+ E G Y G N+T+NSVVAMVPSE+P++IMYVT+Q
Sbjct: 536 AAGAPVIQVGNQSVAVKSGTAQIAQEGGGGYLQGKNDTINSVVAMVPSENPDFIMYVTIQ 595
Query: 597 EPKTWNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTE-ETSYQTGDIIGKTPGETAN 655
+P+ ++ F+ VVNPVLE+A +M T+ + G +E +T Y+ I+G+ PG A
Sbjct: 596 QPEKFSITFWKDVVNPVLEQATAMKETI---LKPGLNDSEHQTKYKLSKIVGENPGHVAE 652
Query: 656 TLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFA 715
LR+NLV PI+LG G+K+ KVS N+ NEQ+L++TN+ TELPDMYGW+K NVE FA
Sbjct: 653 ELRRNLVQPIILGNGSKVSKVSKRPGANLAENEQLLVLTNKLTELPDMYGWSKANVEQFA 712
Query: 716 KWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
KW GIK+TYKG SG V KQS+ G++++K KKI IT+GD
Sbjct: 713 KWTGIKVTYKGSTSGKVRKQSIDVGKSINKIKKIKITIGD 752
>gi|25010351|ref|NP_734746.1| hypothetical protein gbs0277 [Streptococcus agalactiae NEM316]
gi|77414792|ref|ZP_00790914.1| penicillin-binding protein 2X [Streptococcus agalactiae 515]
gi|23094703|emb|CAD45922.1| unknown [Streptococcus agalactiae NEM316]
gi|77159154|gb|EAO70343.1| penicillin-binding protein 2X [Streptococcus agalactiae 515]
Length = 752
Score = 753 bits (1945), Expect = 0.0, Method: Composition-based stats.
Identities = 441/760 (58%), Positives = 569/760 (74%), Gaps = 13/760 (1%)
Query: 1 MNRLKKLKHLFLNYVV--RDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKF 58
M KKLK +FL+YV+ RDRR P +NR+ VGQNLM+L+IF+FF+FIINFV+I+GTDSKF
Sbjct: 1 MTFFKKLKKIFLDYVIHIRDRRSPQKNRERVGQNLMILTIFLFFIFIINFVIIVGTDSKF 60
Query: 59 GVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYV 118
GV+LS +A K Y V AKRGTIYDRNGN +AED+T+YS+YAI+S +Y + T +KLYV
Sbjct: 61 GVNLSKEAKKVYQQSMTVQAKRGTIYDRNGNPIAEDATTYSLYAIISKNYTTATGQKLYV 120
Query: 119 QESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAG 178
Q SQ++KVA IL++KLG+KK+ L QL K +QVSFG G G++Y+ D++KT + +
Sbjct: 121 QPSQYEKVASILENKLGMKKNLVLKQLNQKKLFQVSFGSSGSGLSYTKMADIKKTMEKSD 180
Query: 179 IKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGE 238
IKG+ F + R+YPNG FAS+F+G P ++ DG L+G TGLE +LN +L+GTDG+
Sbjct: 181 IKGIGFSTSPGRIYPNGIFASQFIGFTLP-QDDGDGK-KLVGNTGLEAALNKVLSGTDGK 238
Query: 239 AIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATV 298
YEKD+ GN LLGT T + A++GK+IYTTLS P+QT LETQMD F E+TKG ASATV
Sbjct: 239 VTYEKDRSGNVLLGTATTERRAVNGKDIYTTLSEPIQTVLETQMDVFAEKTKGKFASATV 298
Query: 299 VNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR-LYEAQYEPGSTMKVMLLSAAINNG 357
VNAKTGEILAT+QRPTYN TL+G KK N LY+ +EPGSTMKVM L++AI++
Sbjct: 299 VNAKTGEILATSQRPTYNPSTLKGYDKKNLGTYNTLLYDNFFEPGSTMKVMTLASAIDSK 358
Query: 358 SFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDK 417
FN Y++A K+ D I DW +NEG+S G M+F QGF++SSNVGM LEQ MG
Sbjct: 359 HFNSTEVYNSAQ-YKIADAVIRDWDVNEGLSSGSYMTFPQGFAHSSNVGMVTLEQKMGRD 417
Query: 418 VWSNYLSLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRAFTAISN 476
W NYLS +KFG PTRFGM+ ES G+ S N V IA SSFGQGI VTQVQMLRAFT+ISN
Sbjct: 418 KWLNYLSKFKFGYPTRFGMLHESGGLFPSDNEVTIAMSSFGQGIGVTQVQMLRAFTSISN 477
Query: 477 NGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNK 536
+G+ML+PQFI + D N GT RTA+KEV+GKP+SK+AAS+TR+YM++VGTDP +GTLY
Sbjct: 478 DGVMLQPQFISSIYDPNTGTSRTARKEVVGKPISKEAASKTRDYMVTVGTDPYYGTLY-- 535
Query: 537 SEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQ 596
+ G+P+IQVGN VAVKSGTAQ+ E G Y G N+T+NSVVAMVPSE+P++IMYVT+Q
Sbjct: 536 AAGAPVIQVGNQSVAVKSGTAQIAQEGGGGYLQGKNDTINSVVAMVPSENPDFIMYVTIQ 595
Query: 597 EPKTWNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTE-ETSYQTGDIIGKTPGETAN 655
+P+ ++ F+ VVNPVLE+A +M T+ + G +E +T Y+ I+G+ PG A
Sbjct: 596 QPEKFSITFWKDVVNPVLEQATAMKETI---LKPGLNDSEHQTKYKLSKIVGENPGHVAE 652
Query: 656 TLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFA 715
LR+NLV PI+LG G+K+ KVS N+ NEQ+L++TN+ TELPDMYGW+K NVE FA
Sbjct: 653 ELRRNLVQPIILGNGSKVSKVSKRPGANLAENEQLLVLTNKLTELPDMYGWSKANVEQFA 712
Query: 716 KWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
KW GIK+TYKG SG V KQS+ G++++K KKI IT+GD
Sbjct: 713 KWTGIKVTYKGSTSGKVRKQSIDVGKSINKIKKIKITIGD 752
>gi|81097077|ref|ZP_00875390.1| Peptidoglycan glycosyltransferase [Streptococcus suis 89/1591]
gi|80976883|gb|EAP40453.1| Peptidoglycan glycosyltransferase [Streptococcus suis 89/1591]
Length = 749
Score = 743 bits (1918), Expect = 0.0, Method: Composition-based stats.
Identities = 399/748 (53%), Positives = 537/748 (71%), Gaps = 9/748 (1%)
Query: 11 FLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSY 70
L YV++ R P++NR+ VGQ+L++L++F+FF+F+INF IIGTDSKFGVDLS +A +
Sbjct: 8 LLRYVLKKRYVPSKNRRRVGQSLLLLTVFVFFLFLINFAYIIGTDSKFGVDLSERADAVH 67
Query: 71 NTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADIL 130
+ V AKRGTIYDR G +AEDST+Y++YAI+ T YVS ++ LYVQ SQF KVA+I
Sbjct: 68 QREVTVQAKRGTIYDRTGIPIAEDSTTYTVYAIIDTEYVSELKKVLYVQSSQFSKVAEIF 127
Query: 131 KDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSR 190
K LG++ +Y + QL QV FG GK I+YS +++ K AGI+G+AF A+ R
Sbjct: 128 KKHLGMETAYVMEQLNQPELKQVYFGTLGKNISYSTMSSIQEEMKAAGIEGIAFNASPGR 187
Query: 191 MYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTL 250
MYPNG FAS F+G A P+EN KDGS+SL G +GLE LN +L G DG+ IYEKD G L
Sbjct: 188 MYPNGNFASIFVGLANPVEN-KDGSHSLQGVSGLEYYLNDILAGQDGKVIYEKDSQGRVL 246
Query: 251 LGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATT 310
GTE + E ++G+++YTT+SA LQ LET M+TF + KG A+AT+V+AKTGEILATT
Sbjct: 247 PGTEKVETETVNGQDVYTTISADLQRSLETNMNTFFDNAKGRYANATLVSAKTGEILATT 306
Query: 311 QRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANG 370
QRP+Y+SDT EG ++G + LY+ +EPGSTMKV+ +++AI+NG+F+PNA Y+N N
Sbjct: 307 QRPSYDSDTKEGLGQEGLLERSLLYQEAFEPGSTMKVLTVASAIDNGTFDPNAYYTN-NE 365
Query: 371 IKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGI 430
+ D +INDW++N G S T+++AQGFS SSNVGMT+L+Q MGD+ W NYL+ ++FG
Sbjct: 366 YVIADAKINDWTLNAGYS-AVTLNYAQGFSLSSNVGMTLLQQQMGDEKWLNYLTKFRFGY 424
Query: 431 PTRFGMVGESSGIVSQ-NSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQV 489
PTRFGM E+ G+V + N V+IA SSFGQGIS Q QMLR+FT+I+NNGIMLEP+FI +
Sbjct: 425 PTRFGMGDEAPGMVPEDNIVSIAMSSFGQGISANQAQMLRSFTSIANNGIMLEPKFISAL 484
Query: 490 ADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNND 549
D N T R + KE +G PVS+QAA +T YMI+VGTDP +GTLY+ P IQV D
Sbjct: 485 YDPNTDTARVSSKEEVGNPVSEQAADDTLRYMINVGTDPVYGTLYSHDLQGPAIQVDGYD 544
Query: 550 VAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATV 609
+AVKSGTA++ E Y G +NSVVAM+P+EDPE+IMYVT+++P+ N + +
Sbjct: 545 IAVKSGTAEIASEDGQGYIKGA--YINSVVAMIPAEDPEFIMYVTIRQPEVLNVLSWRDI 602
Query: 610 VNPVLEEAMSM--GATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVL 667
V+P L+EAM + LD+ + ET YQ D+IGK PGE+A LR+ LV P++L
Sbjct: 603 VSPTLKEAMLLKDNLNLDSPAPALARVANETEYQLPDLIGKAPGESAEELRRQLVQPVIL 662
Query: 668 GVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGG 727
G G +I+KVSV+ + AN+Q+L++TN+F E+PD+Y TK+N++ FA+W GI++TYKG
Sbjct: 663 GNGAEIKKVSVEKGSKVIANQQVLLLTNKFEEMPDLYAITKENMDIFAEWTGIEVTYKGT 722
Query: 728 KSGTVTKQSVAAGEALSKTKKITITLGD 755
S V QSV G AL+KTKKITITLGD
Sbjct: 723 GS-KVVDQSVEVGTALNKTKKITITLGD 749
>gi|146319396|ref|YP_001199108.1| Cell division protein FtsI/penicillin-binding protein 2
[Streptococcus suis 05ZYH33]
gi|146321600|ref|YP_001201311.1| Cell division protein FtsI/penicillin-binding protein 2
[Streptococcus suis 98HAH33]
gi|145690202|gb|ABP90708.1| Cell division protein FtsI/penicillin-binding protein 2
[Streptococcus suis 05ZYH33]
gi|145692406|gb|ABP92911.1| Cell division protein FtsI/penicillin-binding protein 2
[Streptococcus suis 98HAH33]
Length = 749
Score = 743 bits (1918), Expect = 0.0, Method: Composition-based stats.
Identities = 400/748 (53%), Positives = 536/748 (71%), Gaps = 9/748 (1%)
Query: 11 FLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSY 70
L YV++ R P++NR+ VGQ+L++L++F+FF+F+INF IIGTDSKFGVDLS +A +
Sbjct: 8 LLRYVLKKRYVPSKNRRRVGQSLLLLTVFVFFLFLINFAYIIGTDSKFGVDLSERADAVH 67
Query: 71 NTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADIL 130
+ IV AKRGTIYDR G +AEDST+Y++YAI+ T YVS ++ LYVQ SQF KVA+I
Sbjct: 68 QREVIVQAKRGTIYDRTGIPIAEDSTTYTVYAIIDTEYVSELKKVLYVQSSQFSKVAEIF 127
Query: 131 KDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSR 190
K LG++ Y + QL QV FG GK I+YS +++ K AGI+G+AF A+ R
Sbjct: 128 KKHLGMETDYVMEQLNQPELKQVYFGTLGKNISYSTMSSIQEEMKAAGIEGIAFNASPGR 187
Query: 191 MYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTL 250
MYPNG FAS F+G A +EN KDGS+SL G +GLE LN +L G DG+ IYEKD G L
Sbjct: 188 MYPNGNFASIFVGLANLVEN-KDGSHSLQGVSGLEYYLNDILAGQDGKVIYEKDSQGRVL 246
Query: 251 LGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATT 310
GTE + E ++G+++YTT+SA LQ LET M+TF + KG A+AT+V+AKTGEILATT
Sbjct: 247 PGTEKVETETVNGQDVYTTISADLQRSLETNMNTFFDNAKGRYANATLVSAKTGEILATT 306
Query: 311 QRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANG 370
QRP+Y+SDT EG ++G + LY+ +EPGSTMKV+ +++AI+NG+F+PNA Y+N N
Sbjct: 307 QRPSYDSDTKEGLGQEGLLERSLLYQEAFEPGSTMKVLTVASAIDNGTFDPNAYYTN-NE 365
Query: 371 IKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGI 430
+ D +INDW++N G S T+++AQGFS SSNVGMT+L+Q MGD+ W NYL+ ++FG
Sbjct: 366 YVIADAKINDWTLNAGYS-AVTLNYAQGFSLSSNVGMTLLQQQMGDEKWLNYLTKFRFGY 424
Query: 431 PTRFGMVGESSGIVSQ-NSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQV 489
PTRFGM E+ G+V + N V+IA SSFGQGIS Q QMLR+FTAI+NNGIMLEP+FI +
Sbjct: 425 PTRFGMGDEAPGMVPEDNIVSIAMSSFGQGISANQAQMLRSFTAIANNGIMLEPKFISAL 484
Query: 490 ADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNND 549
D N T R + KE +G PVS+QAA +T YMI+VGTDP +GTLY+ P IQV D
Sbjct: 485 YDPNTDTARVSSKEEVGNPVSEQAADDTLRYMINVGTDPVYGTLYSHDLQGPAIQVDGYD 544
Query: 550 VAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATV 609
+AVKSGTA++ E Y G +NSVVAM+P+EDPE+IMYVT+++P+ N + +
Sbjct: 545 IAVKSGTAEIASEDGQGYIKGA--YINSVVAMIPAEDPEFIMYVTIRQPEVLNVLSWRDI 602
Query: 610 VNPVLEEAMSM--GATLDTSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVL 667
V+P L+EAM + LD+ + ET YQ D+IGK PGE+A LR+ LV P++L
Sbjct: 603 VSPTLKEAMLLKDNLNLDSPAPALARVANETEYQLPDLIGKAPGESAEELRRQLVQPVIL 662
Query: 668 GVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGG 727
G G +I+KVSV+ + AN+Q+L++TN+F E+PD+Y TK+N++ FA+W GI++TYKG
Sbjct: 663 GNGAEIKKVSVEKGSKVIANQQVLLLTNKFEEMPDLYAITKENMDIFAEWTGIEVTYKGT 722
Query: 728 KSGTVTKQSVAAGEALSKTKKITITLGD 755
S V QSV G AL+KTKKITITLGD
Sbjct: 723 GS-KVVDQSVEVGTALNKTKKITITLGD 749
>gi|38142227|dbj|BAD00916.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 723 bits (1866), Expect = 0.0, Method: Composition-based stats.
Identities = 383/747 (51%), Positives = 537/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGSTMKVM L+++I+N +F P+ Y N++ +
Sbjct: 307 RPTFDADTKEGLTKD-FVWRDILYQSNYEPGSTMKVMTLASSIDNNTF-PSGEYFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV I DW +N+G++ GR M+F QGF+ SSNVGM++LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTIRDWDVNDGLTTGRMMTFLQGFALSSNVGMSLLEQKMGDTTWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++GKPVS+ AAS TR MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGKPVSEDAASLTRTNMILVGTDPIYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ + T E+SY I +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKESLNLQSPAKNLDQVTTESSYAMPSIKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142269|dbj|BAD00937.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 721 bits (1862), Expect = 0.0, Method: Composition-based stats.
Identities = 377/747 (50%), Positives = 533/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 68 ITRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L + ++Y QL QVSFG KG GITY+ ++K KDA ++G+ F + +R
Sbjct: 128 KYLDMDEAYVKEQLAQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +GLE SLN++L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGLESSLNTILAGTDGIITYEKDRVGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ V
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFV 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PG+ A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGDLAEELRRNIVQPIVIG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S++ +N+ N+Q+L+++++ E+PDMYGWTK E F+KW I++ ++G
Sbjct: 665 AGTKIKNASIEEGKNLAPNQQVLLLSDKVEEIPDMYGWTKTTAEAFSKWLNIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|149018028|ref|ZP_01834487.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP23-BS72]
gi|147931592|gb|EDK82570.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP23-BS72]
Length = 750
Score = 721 bits (1860), Expect = 0.0, Method: Composition-based stats.
Identities = 377/747 (50%), Positives = 537/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GRTM+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + SVV+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTDYIFSVVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142209|dbj|BAD00907.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 720 bits (1858), Expect = 0.0, Method: Composition-based stats.
Identities = 379/747 (50%), Positives = 536/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGSTMKVM L+++I+N +F P+ Y N++ +
Sbjct: 307 RPTFDADTKEGLTKD-FVWRDILYQSNYEPGSTMKVMTLASSIDNNTF-PSGEYFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV I DW +N+G++ GR M+F QGF+ SSNVGM++LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTIRDWDVNDGLTTGRMMTFLQGFALSSNVGMSLLEQKMGDTTWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++GKPVS+ AAS TR MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGKPVSEDAASLTRTNMILVGTDPIYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ + T E+SY I +PG+ A LR+N+V PIV+G
Sbjct: 605 NPILERASAMKESLNLQSPAKNLDQVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ +N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGKNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142201|dbj|BAD00903.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 719 bits (1857), Expect = 0.0, Method: Composition-based stats.
Identities = 379/747 (50%), Positives = 537/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +N+G++ G M+F+QGF++SSNVGM++LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNDGLTTGGMMTFSQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIA S+FGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYTGQLPADNIVNIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR +KKE++GKPVS+ AAS TR MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSKKEIVGKPVSEDAASLTRTNMILVGTDPLYGTMYNHHTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A++M +L+ ++ T +++Y I +PG+ A LR+N+V PIV+G
Sbjct: 605 NPILERAVAMKDSLNLQSTAKTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+LI++++ E+PDMYGWTK ETFAKW I + ++G
Sbjct: 665 TGTKIKESSVEEGANLTPNQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIDLEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|76787444|ref|YP_329011.1| penicillin-binding protein 2X [Streptococcus agalactiae A909]
gi|76562501|gb|ABA45085.1| penicillin-binding protein 2X [Streptococcus agalactiae A909]
Length = 717
Score = 719 bits (1856), Expect = 0.0, Method: Composition-based stats.
Identities = 408/706 (57%), Positives = 524/706 (74%), Gaps = 11/706 (1%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GTDSKFGV+LS +A K Y V AKRGTIYDRNGN +AED+T+YS+YAI+S +Y + T
Sbjct: 20 GTDSKFGVNLSKEAKKVYQQSMTVQAKRGTIYDRNGNPIAEDATTYSLYAIISKNYTTAT 79
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+KLYVQ SQ++KVA IL++KLG+KK+ L QL K +QVSFG G G++Y+ D++K
Sbjct: 80 GQKLYVQPSQYEKVASILENKLGMKKNLVLKQLNQKKLFQVSFGSSGSGLSYTKMADIKK 139
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
T + + IKG+ F + R+YPNG FAS+F+G P ++ DG L+G TGLE +LN +L
Sbjct: 140 TMEKSDIKGIGFSTSPGRIYPNGIFASQFIGFTLP-QDDGDGK-KLVGNTGLEAALNKVL 197
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
+GTDG+ YEKD+ GN LLGT T + A++GK+IYTTLS P+QT LETQMD F E+TKG
Sbjct: 198 SGTDGKVTYEKDRSGNVLLGTATTERRAVNGKDIYTTLSEPIQTVLETQMDVFAEKTKGK 257
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR-LYEAQYEPGSTMKVMLLS 351
ASATVVNAKTGEILAT+QRPTYN TL+G KK N LY+ +EPGSTMKVM L+
Sbjct: 258 FASATVVNAKTGEILATSQRPTYNPSTLKGYDKKNLGTYNTLLYDNFFEPGSTMKVMTLA 317
Query: 352 AAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLE 411
+AI++ FN Y++A K+ D I DW +NEG+S G M+F QGF++SSNVGM LE
Sbjct: 318 SAIDSKHFNSTEVYNSAQ-YKIADAIIRDWDVNEGLSSGSYMTFPQGFAHSSNVGMVTLE 376
Query: 412 QAMGDKVWSNYLSLYKFGIPTRFGMVGESSGIV-SQNSVNIAQSSFGQGISVTQVQMLRA 470
Q MG W NYLS +KFG PTRFGM+ ES G+ S N V IA SSFGQGI VTQVQMLRA
Sbjct: 377 QKMGRDKWLNYLSKFKFGYPTRFGMLHESGGLFPSDNEVTIAMSSFGQGIGVTQVQMLRA 436
Query: 471 FTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEF 530
FT+ISN+G+ML+PQFI + D N GT RTA+KEV+GKPVSK+AAS+TR+YM++VGTDP +
Sbjct: 437 FTSISNDGVMLQPQFISSIYDPNTGTSRTARKEVVGKPVSKEAASKTRDYMVTVGTDPYY 496
Query: 531 GTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYI 590
GTLY + G+P+IQVGN VAVKSGTAQ+ E G Y G N+T+NSVVAMVPSE+P++I
Sbjct: 497 GTLY--AAGAPVIQVGNQSVAVKSGTAQIAQEGGGGYLQGKNDTINSVVAMVPSENPDFI 554
Query: 591 MYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGKTE-ETSYQTGDIIGKT 649
MYVT+Q+P+ ++ F+ VVNPVLE+A +M T+ + G +E +T Y+ I+G+
Sbjct: 555 MYVTIQQPEKFSITFWKDVVNPVLEQATAMKETI---LKPGLNDSEHQTKYKLSKIVGEN 611
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PG A LR+NLV PI+LG G+K+ KVS N+ NEQ+L++TN+ TELPDMYGW+K
Sbjct: 612 PGHVAEELRRNLVQPIILGNGSKVSKVSKRPGANLAENEQLLVLTNKLTELPDMYGWSKA 671
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
NVE FAKW GIK+TYKG SG V KQS+ G++++K KKI IT+GD
Sbjct: 672 NVEQFAKWTGIKVTYKGSTSGKVRKQSIDVGKSINKIKKIKITIGD 717
>gi|15900267|ref|NP_344871.1| penicillin-binding protein 2X [Streptococcus pneumoniae TIGR4]
gi|111657192|ref|ZP_01407967.1| hypothetical protein SpneT_02001589 [Streptococcus pneumoniae
TIGR4]
gi|18266817|sp|P14677|PBPX_STRPN Penicillin-binding protein 2x (PBP-2x) (PBP2x)
gi|14971809|gb|AAK74511.1| penicillin-binding protein 2X [Streptococcus pneumoniae TIGR4]
Length = 750
Score = 719 bits (1856), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 536/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GRTM+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|116517037|ref|YP_815823.1| penicillin-binding protein 2X [Streptococcus pneumoniae D39]
gi|116077613|gb|ABJ55333.1| penicillin-binding protein 2X [Streptococcus pneumoniae D39]
Length = 750
Score = 719 bits (1855), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 535/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142235|dbj|BAD00920.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 718 bits (1854), Expect = 0.0, Method: Composition-based stats.
Identities = 381/747 (51%), Positives = 537/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGSTMKVM L+A+I+N +F P Y N++ +
Sbjct: 307 RPTFDADTKEGLTKD-FVWRDILYQSNYEPGSTMKVMTLAASIDNNTF-PGGEYFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV I DW +N+G++ GR M+F QGF+ SSNVGM++LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTIRDWDVNDGLTTGRMMTFLQGFALSSNVGMSLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++GKPVS+ AAS TR MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGKPVSEDAASLTRTNMILVGTDPLYGTMYNHQTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSAAQLGEFS 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK ETFAKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|55167243|dbj|BAD67448.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 718 bits (1854), Expect = 0.0, Method: Composition-based stats.
Identities = 375/747 (50%), Positives = 534/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNHQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|148996750|ref|ZP_01824468.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP11-BS70]
gi|149006087|ref|ZP_01829816.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP18-BS74]
gi|149013060|ref|ZP_01833926.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP19-BS75]
gi|38142197|dbj|BAD00901.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|147757325|gb|EDK64364.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP11-BS70]
gi|147762443|gb|EDK69404.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP18-BS74]
gi|147763095|gb|EDK70037.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP19-BS75]
Length = 750
Score = 718 bits (1854), Expect = 0.0, Method: Composition-based stats.
Identities = 375/747 (50%), Positives = 535/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|6563353|gb|AAF17263.1|AF210753_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 718 bits (1854), Expect = 0.0, Method: Composition-based stats.
Identities = 375/747 (50%), Positives = 535/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQXNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142219|dbj|BAD00912.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 718 bits (1854), Expect = 0.0, Method: Composition-based stats.
Identities = 373/747 (49%), Positives = 537/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLN +L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNRILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGS MKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSPMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS+TR +M+ VGTDP +GT++N S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASQTRTHMVLVGTDPVYGTMHNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y +G+ + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLIGSTNHIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|148988092|ref|ZP_01819555.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP6-BS73]
gi|147926556|gb|EDK77629.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP6-BS73]
Length = 750
Score = 718 bits (1853), Expect = 0.0, Method: Composition-based stats.
Identities = 378/747 (50%), Positives = 535/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE I+++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQISQQTVDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG K + W + LY++ YEPGS MKVM L+A+I+N +F P Y N++ +
Sbjct: 307 RPTFNADTKEG-ITKDFVWRDILYQSNYEPGSAMKVMTLAASIDNNTF-PGGEYFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV I DW +NEG++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTIRDWDVNEGLTGGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTNYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLDTSVSEGSGK--TEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ + S + ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKSLEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK ETFAKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
+ TV KQ V A A+ KKIT+TLGD
Sbjct: 725 T-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|6563367|gb|AAF17270.1|AF210760_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 718 bits (1853), Expect = 0.0, Method: Composition-based stats.
Identities = 378/747 (50%), Positives = 534/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T IV AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRIVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGEVAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|6563357|gb|AAF17265.1|AF210755_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|4009488|gb|AAC95456.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 750
Score = 717 bits (1852), Expect = 0.0, Method: Composition-based stats.
Identities = 373/747 (49%), Positives = 539/747 (72%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIA S+FGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N +VR ++KE++G PVSK+AAS TR++M+ VGTDP +GT+YN S G + V +V
Sbjct: 485 DPNDQSVRKSQKEIVGNPVSKEAASVTRDHMVMVGTDPTYGTMYNHSTGKATVNVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTA++ DEK G Y G+ + SVV+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAEIADEKNGGYLTGSTNNIFSVVSMHPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKESLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142231|dbj|BAD00918.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 717 bits (1852), Expect = 0.0, Method: Composition-based stats.
Identities = 375/747 (50%), Positives = 537/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A++M +L+ ++ T +++Y I +PG+ A LR+N+V PIV+G
Sbjct: 605 NPILERAVAMKDSLNLQSTAKTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGWTK E F+KW I++ ++G
Sbjct: 665 TGTKIKESSVEEGSNLAPNQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|15902348|ref|NP_357898.1| Penicillin-binding protein 2X [Streptococcus pneumoniae R6]
gi|148983742|ref|ZP_01817061.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP3-BS71]
gi|30913153|sp|P59676|PBPX_STRR6 Penicillin-binding protein 2X (PBP-2X) (PBP2X)
gi|47392|emb|CAA34412.1| unnamed protein product [Streptococcus pneumoniae]
gi|15457858|gb|AAK99108.1| Penicillin-binding protein 2X [Streptococcus pneumoniae R6]
gi|147923889|gb|EDK75001.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP3-BS71]
Length = 750
Score = 717 bits (1852), Expect = 0.0, Method: Composition-based stats.
Identities = 375/747 (50%), Positives = 535/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142203|dbj|BAD00904.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 717 bits (1851), Expect = 0.0, Method: Composition-based stats.
Identities = 375/747 (50%), Positives = 535/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLEEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|6563359|gb|AAF17266.1|AF210756_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 717 bits (1850), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 536/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY + QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVIEQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P+ Y N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PSGEYFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIA S+FGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR MI VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTA++ DEK G Y VG+ + SVVAM P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAEIADEKNGGYLVGSTNNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFT 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK ETFAKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|148994364|ref|ZP_01823607.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP9-BS68]
gi|147927295|gb|EDK78328.1| S-adenosyl-methyltransferase MraW [Streptococcus pneumoniae
SP9-BS68]
Length = 750
Score = 717 bits (1850), Expect = 0.0, Method: Composition-based stats.
Identities = 378/747 (50%), Positives = 534/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIIP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGVEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR MI VGTD +GT+YN S G P + V +V
Sbjct: 485 DPNYQTARKSQKEIVGNPVSKDAASLTRTNMILVGTDSVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTA++ DEK G Y VG+ + SVVAM P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAEIADEKNGGYLVGSTNNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLSPNQQVLILSDKAEEVPDMYGWTKATAETLAKWLNIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142199|dbj|BAD00902.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 716 bits (1849), Expect = 0.0, Method: Composition-based stats.
Identities = 374/747 (50%), Positives = 534/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSG AQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGAAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142205|dbj|BAD00905.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|38142237|dbj|BAD00921.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 716 bits (1849), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 535/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGSTMKVM L+AAI+N +F P +++ +
Sbjct: 307 RPTFDADTKEGLTKD-FVWRDILYQSNYEPGSTMKVMTLAAAIDNNTF-PGGEVFDSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV I DW +NEG++ GR M+ +QGF+ SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTIRDWDVNEGLTGGRMMTLSQGFALSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N +VR ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQSVRKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142241|dbj|BAD00923.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|38142243|dbj|BAD00924.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|38142263|dbj|BAD00934.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 716 bits (1848), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 533/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKIT+TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKITLTLGD 750
>gi|38142247|dbj|BAD00926.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 715 bits (1846), Expect = 0.0, Method: Composition-based stats.
Identities = 377/747 (50%), Positives = 532/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142259|dbj|BAD00932.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 715 bits (1845), Expect = 0.0, Method: Composition-based stats.
Identities = 377/747 (50%), Positives = 532/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ +
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHITSVQLGEFS 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 NPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|6563363|gb|AAF17268.1|AF210758_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 715 bits (1845), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 533/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142213|dbj|BAD00909.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 714 bits (1844), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 537/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T IV AKRGTIYDRNG +AED TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRIVPAKRGTIYDRNGVPIAEDETSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGS MKVM L+++I+N +F P Y N++ +
Sbjct: 307 RPTFDADTKEGLTKD-FVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PGGEYFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV DW +NEG++ G M+F+QGF++SSNVGM++LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTTRDWDVNEGLTVGGMMTFSQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N TVR ++KE++G PVSK AAS+TR +M+ VGTDP +GT+YN G PII V +V
Sbjct: 485 DPNDQTVRKSQKEIVGNPVSKDAASQTRTHMVLVGTDPIYGTMYNHQTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A++M +L+ ++ T +++Y I +PG+ A LR+N+V PIV+G
Sbjct: 605 NPILERAVAMKDSLNLQSTAKTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGWTK E F+KW I+I ++G
Sbjct: 665 TGTKIKESSVEEGTNLAPNQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIEIVFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|6563361|gb|AAF17267.1|AF210757_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 714 bits (1844), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 536/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T IV AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRIVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 TPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G
Sbjct: 665 TGTKIKNSSAEEGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142207|dbj|BAD00906.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 714 bits (1843), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 531/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLN +L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNRILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142215|dbj|BAD00910.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 714 bits (1842), Expect = 0.0, Method: Composition-based stats.
Identities = 377/747 (50%), Positives = 532/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGWTK E F+KW I+I ++G
Sbjct: 665 TGTKIKESSVEEGTNLAPNQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIEIVFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142245|dbj|BAD00925.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 714 bits (1842), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 532/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQSGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142271|dbj|BAD00938.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 713 bits (1841), Expect = 0.0, Method: Composition-based stats.
Identities = 375/747 (50%), Positives = 531/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLTQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142221|dbj|BAD00913.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 713 bits (1841), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 531/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142267|dbj|BAD00936.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 713 bits (1840), Expect = 0.0, Method: Composition-based stats.
Identities = 376/747 (50%), Positives = 533/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T IV AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRIVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YLS +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLSRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142249|dbj|BAD00927.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 713 bits (1840), Expect = 0.0, Method: Composition-based stats.
Identities = 374/747 (50%), Positives = 531/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PG+ A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGDLAEELRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 AGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142265|dbj|BAD00935.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 712 bits (1838), Expect = 0.0, Method: Composition-based stats.
Identities = 377/747 (50%), Positives = 532/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A ++G+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKKDLETAKVEGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SLIG +G+E SLNSLL GTDG YEKD+ GN +
Sbjct: 188 YPNGKFASSFIGLAQLHENE-DGSKSLIGTSGVESSLNSLLAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +T++ ++GK++YTTLS+PLQ+F+E+QMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVTRQTVNGKDVYTTLSSPLQSFMESQMDAFQEKLKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142253|dbj|BAD00929.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 712 bits (1837), Expect = 0.0, Method: Composition-based stats.
Identities = 378/747 (50%), Positives = 532/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGSTMKVM L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITKDFVWRDILYQSNYEPGSTMKVMTLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV I DW +N+G++ GR M+F QGF+ SSNVGM++LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTIRDWDVNDGLTTGRMMTFLQGFALSSNVGMSLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN G PII V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHQTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSAVQLGEFS 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ + T E+SY I +PG+ A LR+N+V PIV+G
Sbjct: 605 NPILERASAMKESLNLQSPAKNLDQVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ +N+ N+Q+L+++++ E+PDMYGWTK E F+KW I++ ++G
Sbjct: 665 TGTKIKETSVEEGKNLAPNQQVLLLSDKVEEIPDMYGWTKATAEAFSKWLNIELVFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|38142223|dbj|BAD00914.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|38142255|dbj|BAD00930.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|38142257|dbj|BAD00931.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|38142261|dbj|BAD00933.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 711 bits (1835), Expect = 0.0, Method: Composition-based stats.
Identities = 375/747 (50%), Positives = 528/747 (70%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIG+ SKFG DL +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 68 ITRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L + ++Y QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMDEAYVKEQLSQPNLTQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|38142229|dbj|BAD00917.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 711 bits (1835), Expect = 0.0, Method: Composition-based stats.
Identities = 373/747 (49%), Positives = 532/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFDADTKEGLTKD-FVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PG+ A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ +N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGKNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|148714948|gb|ABR03900.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714952|gb|ABR03902.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 711 bits (1834), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 530/736 (72%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GRTM+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + SVV+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTDYIFSVVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|38142273|dbj|BAD00939.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 710 bits (1833), Expect = 0.0, Method: Composition-based stats.
Identities = 374/747 (50%), Positives = 531/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 ITRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVG ++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|18652354|gb|AAL77081.1|AF468152_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 710 bits (1833), Expect = 0.0, Method: Composition-based stats.
Identities = 376/745 (50%), Positives = 531/745 (71%), Gaps = 7/745 (0%)
Query: 14 YVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTK 73
+ +R+R+ PA+NR+ VG+ + +L++ +F VF++NF VIIG+ SKFG DL +A K +
Sbjct: 10 FAIRNRKSPAENRKIVGKYISLLAVVLFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQIT 69
Query: 74 TIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDK 133
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 70 RTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKY 129
Query: 134 LGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYP 193
L + ++Y QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YP
Sbjct: 130 LDMDEAYVKEQLAQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYP 189
Query: 194 NGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGT 253
NG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GT
Sbjct: 190 NGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGT 248
Query: 254 ETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRP 313
E ++++ +DGK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRP
Sbjct: 249 EQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRP 308
Query: 314 TYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKV 373
T+++DT EG K + W + LY++ YEPGSTMKVM L+AAI+N +F P N++ +K+
Sbjct: 309 TFDADTKEGLTKD-FVWRDILYQSNYEPGSTMKVMTLAAAIDNNTF-PGGEVFNSSELKI 366
Query: 374 GDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTR 433
DV I DW +NEG++ GR M+F+QGF+ SSNVGMT+LEQ MGD W +YL+ +KFG+PTR
Sbjct: 367 ADVTIRDWDVNEGLTGGRMMTFSQGFALSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTR 426
Query: 434 FGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADT 492
FG+ E +G + + N VNIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DT
Sbjct: 427 FGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDT 486
Query: 493 NKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAV 552
N +VR ++KE++GKPVS+ AAS TR MI VGTDP +GT+YN G PII V +VAV
Sbjct: 487 NNQSVRKSQKEIVGKPVSEDAASLTRTNMILVGTDPLYGTMYNHQTGKPIITVPGQNVAV 546
Query: 553 KSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNP 612
KSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ NP
Sbjct: 547 KSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFANP 606
Query: 613 VLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVG 670
+LE A++M +L+ ++ T +++Y I +PG+ A LR+N+V PIV+G G
Sbjct: 607 ILERAVAMKDSLNLQSTAKTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVGTG 666
Query: 671 NKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSG 730
KI++ SV+ N+ N+Q+L+++++ E+PDMYGWTK E F+KW I++ ++G S
Sbjct: 667 TKIKESSVEEGTNLAPNQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSGS- 725
Query: 731 TVTKQSVAAGEALSKTKKITITLGD 755
TV KQ V A A+ KKI +TLGD
Sbjct: 726 TVQKQDVRANTAIKDIKKIKLTLGD 750
>gi|148714872|gb|ABR03862.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 710 bits (1832), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 529/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ETFAKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148715106|gb|ABR03979.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 709 bits (1831), Expect = 0.0, Method: Composition-based stats.
Identities = 375/736 (50%), Positives = 529/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148714904|gb|ABR03878.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 709 bits (1831), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 529/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GRTM+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|38142233|dbj|BAD00919.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 709 bits (1831), Expect = 0.0, Method: Composition-based stats.
Identities = 373/747 (49%), Positives = 533/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE + ++ +DGK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVFQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGSTMKVM L+AAI+N +F P +++ +
Sbjct: 307 RPTFDADTKEGLTKD-FVWRDILYQSNYEPGSTMKVMTLAAAIDNNTF-PGGEVFDSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ DV I DW +NEG++ GR M+F+QGF SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADVTIRDWDVNEGLTGGRMMTFSQGFVLSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISALY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N +VR ++KE++G PVSK+AAS TR+YM+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQSVRKSQKEIVGNPVSKEAASVTRDYMVMVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A++M +L+ ++ + +TSY I +PG+ A LR+N+V PIV+G
Sbjct: 605 NPILERAVAMKDSLNLQSTAKALDQISSQTSYAMPSIKDISPGDLAEELRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|148714866|gb|ABR03859.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 709 bits (1829), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 529/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD+F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI V D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|38142239|dbj|BAD00922.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 709 bits (1829), Expect = 0.0, Method: Composition-based stats.
Identities = 374/747 (50%), Positives = 530/747 (70%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|6563355|gb|AAF17264.1|AF210754_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 709 bits (1829), Expect = 0.0, Method: Composition-based stats.
Identities = 374/747 (50%), Positives = 536/747 (71%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG K + W + LY++ YEPGSTMKVM L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEGLTKD-FVWRDILYQSNYEPGSTMKVMTLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
KV D I DW +NEG++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFGIP
Sbjct: 365 KVADATIRDWDVNEGLTGGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGIP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N +VR ++KE++G PVSK AAS+TR +M+ VGTDP +GT+YN S G + V +V
Sbjct: 485 DPNNQSVRKSQKEIVGNPVSKDAASQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTA++ DEK G Y VG+ + SVVAM P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAEIADEKNGGYLVGSTNHIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A++M +L+ ++ T +++Y I +PG+ A LR+N+V PIV+G
Sbjct: 605 NPILERAVAMKDSLNLQSTAKTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGWTK E F+KW I++ ++G
Sbjct: 665 TGTKIKESSVEEGSNLAPNQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S TV KQ V A A+ KKIT+TLGD
Sbjct: 725 S-TVQKQDVRANTAIKDIKKITLTLGD 750
>gi|148715114|gb|ABR03983.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 709 bits (1829), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 524/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714940|gb|ABR03896.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714944|gb|ABR03898.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 709 bits (1829), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 529/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GRTM+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148714876|gb|ABR03864.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 708 bits (1828), Expect = 0.0, Method: Composition-based stats.
Identities = 372/736 (50%), Positives = 528/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148715172|gb|ABR04012.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715292|gb|ABR04072.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 708 bits (1827), Expect = 0.0, Method: Composition-based stats.
Identities = 375/736 (50%), Positives = 528/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE I+++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQISQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+A+I+N +F P Y N++ +K+ DV I DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAASIDNNTF-PGGEYFNSSELKIADVTIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTNYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLDTSVSEGSGK--TEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + S + ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKSLEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK ETFAKW I++ ++G + TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIELEFEGSGT-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148714902|gb|ABR03877.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714918|gb|ABR03885.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714934|gb|ABR03893.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714936|gb|ABR03894.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714942|gb|ABR03897.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715006|gb|ABR03929.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 708 bits (1827), Expect = 0.0, Method: Composition-based stats.
Identities = 372/736 (50%), Positives = 528/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|2315993|gb|AAC45547.1| low-affinity penicillin-binding protein 2X [Streptococcus
pneumoniae]
Length = 750
Score = 707 bits (1826), Expect = 0.0, Method: Composition-based stats.
Identities = 374/745 (50%), Positives = 527/745 (70%), Gaps = 7/745 (0%)
Query: 14 YVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTK 73
+ +R+R+ PA+NR+ VG+ + +L++ +F VF++NF VIIG+ SKFG DL +A K +
Sbjct: 10 FAIRNRKSPAENRKIVGKYISLLAVVLFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQIT 69
Query: 74 TIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDK 133
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 70 RTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKY 129
Query: 134 LGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYP 193
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R YP
Sbjct: 130 LDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYP 189
Query: 194 NGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGT 253
NG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GT
Sbjct: 190 NGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGT 248
Query: 254 ETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRP 313
E ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRP
Sbjct: 249 ELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRP 308
Query: 314 TYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKV 373
T+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+
Sbjct: 309 TFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKI 366
Query: 374 GDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTR 433
D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTR
Sbjct: 367 ADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTR 426
Query: 434 FGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADT 492
FG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DT
Sbjct: 427 FGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDT 486
Query: 493 NKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAV 552
N +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAV
Sbjct: 487 NNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAV 546
Query: 553 KSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNP 612
KSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P
Sbjct: 547 KSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATP 606
Query: 613 VLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVG 670
+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G G
Sbjct: 607 ILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTG 666
Query: 671 NKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSG 730
KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S
Sbjct: 667 TKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS- 725
Query: 731 TVTKQSVAAGEALSKTKKITITLGD 755
V KQ V A+ KKI +TLGD
Sbjct: 726 VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|148714914|gb|ABR03883.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714986|gb|ABR03919.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715070|gb|ABR03961.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 707 bits (1826), Expect = 0.0, Method: Composition-based stats.
Identities = 371/736 (50%), Positives = 528/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+F+ + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFLSAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148714862|gb|ABR03857.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714906|gb|ABR03879.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715164|gb|ABR04008.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 707 bits (1826), Expect = 0.0, Method: Composition-based stats.
Identities = 372/736 (50%), Positives = 528/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148715282|gb|ABR04067.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 707 bits (1826), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 527/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715132|gb|ABR03992.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 707 bits (1824), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 527/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715096|gb|ABR03974.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 707 bits (1824), Expect = 0.0, Method: Composition-based stats.
Identities = 372/733 (50%), Positives = 527/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GRTM+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + SVV+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGLTDYIFSVVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148714958|gb|ABR03905.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 706 bits (1823), Expect = 0.0, Method: Composition-based stats.
Identities = 371/736 (50%), Positives = 525/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQITRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR +M+ VGTDP +GT+YN S G + V +VA+KSGTA++ D
Sbjct: 478 KEIVGNPVSKDAASLTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAEIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGSTNNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|6563365|gb|AAF17269.1|AF210759_1 penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 706 bits (1823), Expect = 0.0, Method: Composition-based stats.
Identities = 373/747 (49%), Positives = 530/747 (70%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS KVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N G++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNAGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN + R ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSGRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHFSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|148715090|gb|ABR03971.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 706 bits (1823), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|38142275|dbj|BAD00940.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 706 bits (1823), Expect = 0.0, Method: Composition-based stats.
Identities = 372/745 (49%), Positives = 526/745 (70%), Gaps = 7/745 (0%)
Query: 14 YVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTK 73
+ +R+R+ PA+NR+ VG+ + +L++ +F VF++NF VIIG+ SKFG DL +A K +
Sbjct: 10 FAIRNRKSPAENRKIVGKYISLLAVVLFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQIT 69
Query: 74 TIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDK 133
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 70 RTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKY 129
Query: 134 LGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYP 193
L + ++Y QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YP
Sbjct: 130 LDMDEAYVKEQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYP 189
Query: 194 NGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGT 253
NG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GT
Sbjct: 190 NGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGT 248
Query: 254 ETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRP 313
E ++++ +DGK++YTTLS+PLQ+F+E+QMD F E+ KG +AT+V+AKTGEILATTQRP
Sbjct: 249 EQVSQQTVDGKDVYTTLSSPLQSFMESQMDAFQEKLKGKYMTATLVSAKTGEILATTQRP 308
Query: 314 TYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKV 373
T+++DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+
Sbjct: 309 TFDADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKI 366
Query: 374 GDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTR 433
D DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTR
Sbjct: 367 ADATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTR 426
Query: 434 FGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADT 492
FG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DT
Sbjct: 427 FGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDT 486
Query: 493 NKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAV 552
N +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAV
Sbjct: 487 NNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAV 546
Query: 553 KSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNP 612
KSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P
Sbjct: 547 KSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATP 606
Query: 613 VLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVG 670
+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G G
Sbjct: 607 ILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTG 666
Query: 671 NKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSG 730
KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S
Sbjct: 667 TKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS- 725
Query: 731 TVTKQSVAAGEALSKTKKITITLGD 755
V KQ V A+ KKI +TLGD
Sbjct: 726 VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|148715118|gb|ABR03985.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715120|gb|ABR03986.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 706 bits (1823), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 523/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K KDA ++ + F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVERIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715248|gb|ABR04050.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715156|gb|ABR04004.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats.
Identities = 372/736 (50%), Positives = 523/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715126|gb|ABR03989.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714890|gb|ABR03871.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats.
Identities = 371/733 (50%), Positives = 526/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GRTM+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148714932|gb|ABR03892.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats.
Identities = 371/733 (50%), Positives = 526/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ETFAKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148715144|gb|ABR03998.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 706 bits (1821), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715210|gb|ABR04031.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 706 bits (1821), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSGMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714920|gb|ABR03886.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 730
Score = 706 bits (1821), Expect = 0.0, Method: Composition-based stats.
Identities = 371/734 (50%), Positives = 526/734 (71%), Gaps = 7/734 (0%)
Query: 25 NRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIY 84
NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIY
Sbjct: 1 NRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY 60
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY Q
Sbjct: 61 DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQ 120
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 121 LSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGL 180
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK
Sbjct: 181 AQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGK 239
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 DVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-I 298
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +N
Sbjct: 299 TEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVN 357
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
EG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 EGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQL 417
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE
Sbjct: 418 PADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKE 477
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 IVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEK 537
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +
Sbjct: 538 NGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDS 597
Query: 624 LD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 LNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEG 657
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 KNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANT 716
Query: 742 ALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 AIKDIKKITLTLGD 730
>gi|125718669|ref|YP_001035802.1| Penicillin-binding protein 2X, putative [Streptococcus sanguinis
SK36]
gi|125498586|gb|ABN45252.1| Penicillin-binding protein 2X, putative [Streptococcus sanguinis
SK36]
Length = 762
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 395/758 (52%), Positives = 535/758 (70%), Gaps = 23/758 (3%)
Query: 14 YVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTK 73
Y +++R+ P NR+ VG+++ +L+IF+FFVF+INF +IIGTD KFGV+LS A +
Sbjct: 12 YALKNRQTPEYNRRQVGKSMSILAIFLFFVFLINFAIIIGTDQKFGVNLSKGAEVVHQKT 71
Query: 74 TIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDK 133
VAA+RGTIYDRNG +AED+T+Y++YAI+ SY S T + LYV+ESQ+DKVA+I
Sbjct: 72 VTVAARRGTIYDRNGVPIAEDATTYNVYAIIDKSYKSATGKILYVEESQYDKVAEIFNQY 131
Query: 134 LGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYP 193
L + K Y QL K QVSFG +G GITYS + + F+ AGI+G+ F + +R Y
Sbjct: 132 LELDKDYVKTQLSQKNLKQVSFGAQGNGITYSNMNAMREAFEAAGIEGIDFTTSPNRSYS 191
Query: 194 NGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGT 253
NG FAS+F+G A+ ++ K+G+ +L G +G+E++L+ +L G +G YEKD++GN + G+
Sbjct: 192 NGVFASQFIGLAQ-LQEDKEGNKTLKGTSGMEQALDRILAGQNGIVTYEKDRNGNVVPGS 250
Query: 254 ETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRP 313
E ++ +A DGK++YTTLSA LQT+LET+M+ F E+ KG +AT+V+AKTGEILAT+QRP
Sbjct: 251 EKVSVQAEDGKDVYTTLSADLQTYLETRMNAFQEKVKGKFVNATLVSAKTGEILATSQRP 310
Query: 314 TYNSDTLEGQAKKGY-DWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIK 372
TYN+DT EG +K +W LY+ QYEPGSTMKVM L++AI+NGSFNPN TY ++ K
Sbjct: 311 TYNADTKEGLNEKNLGNWNTMLYQGQYEPGSTMKVMTLASAIDNGSFNPNDTY-DSREYK 369
Query: 373 VGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPT 432
V D I DW++N GIS+G T++FAQGF+YSSNVGMT+LEQ MG+ W +YLS +KFG+PT
Sbjct: 370 VMDATIRDWNVNMGISEGETLTFAQGFTYSSNVGMTILEQKMGNDKWLDYLSKFKFGLPT 429
Query: 433 RFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVAD 491
RFGM E+ G + N V IA SSFGQGI VTQVQMLRAF++++N+G+M+EP+FI + D
Sbjct: 430 RFGMGNETYGSLPGDNYVTIAMSSFGQGIGVTQVQMLRAFSSVANDGVMVEPKFINAIHD 489
Query: 492 TNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVA 551
T R E+IG PVS++AA TR+YM+ VGTDP GTL G P+IQV +VA
Sbjct: 490 PKNNTARKTATEIIGNPVSEKAAQTTRDYMVQVGTDPYHGTL--NVGGEPVIQVAGQNVA 547
Query: 552 VKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEP-KTWNNNFFATVV 610
VKSGTAQ+ E Y G N+ + SVVAM P+E+PE+IMYVTVQ+P + + F+ VV
Sbjct: 548 VKSGTAQIASEN--GYLEGENDYIYSVVAMTPAENPEFIMYVTVQQPEEKFQPIFWQEVV 605
Query: 611 NPVLEEAMSMGATLDTSVSEG---SGKTEETSYQTGDIIGKT----------PGETANTL 657
NPVLEEA+++ +L+ + TEETSY+ + T PG A+ L
Sbjct: 606 NPVLEEAVALKDSLNLTTEATPVLETVTEETSYKMPSLEDLTKQLGLKHQISPGGLADEL 665
Query: 658 RQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKW 717
R+NLV PIVLG G KI+KVSV +N+KAN+Q+LI++++ LPDMYGWTK NVE FAKW
Sbjct: 666 RRNLVQPIVLGTGGKIKKVSVKEGKNLKANQQVLILSDDLDSLPDMYGWTKANVERFAKW 725
Query: 718 KGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
+ I++T+KG S V KQS +L KKITIT+GD
Sbjct: 726 QDIEVTFKGEGS-KVVKQSEKTNTSLKNLKKITITMGD 762
>gi|148714868|gb|ABR03860.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 371/736 (50%), Positives = 527/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF +IIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAIIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148714930|gb|ABR03891.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 371/733 (50%), Positives = 525/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A IKG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEIKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148715238|gb|ABR04045.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 375/736 (50%), Positives = 524/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714954|gb|ABR03903.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714964|gb|ABR03908.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714974|gb|ABR03913.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714980|gb|ABR03916.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715004|gb|ABR03928.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715014|gb|ABR03933.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715016|gb|ABR03934.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715020|gb|ABR03936.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715022|gb|ABR03937.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715024|gb|ABR03938.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715026|gb|ABR03939.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715028|gb|ABR03940.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715030|gb|ABR03941.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715032|gb|ABR03942.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715066|gb|ABR03959.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715084|gb|ABR03968.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715088|gb|ABR03970.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715094|gb|ABR03973.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715104|gb|ABR03978.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715108|gb|ABR03980.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715110|gb|ABR03981.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715112|gb|ABR03982.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715128|gb|ABR03990.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715136|gb|ABR03994.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715138|gb|ABR03995.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715166|gb|ABR04009.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715168|gb|ABR04010.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715170|gb|ABR04011.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715180|gb|ABR04016.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715190|gb|ABR04021.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715218|gb|ABR04035.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715254|gb|ABR04053.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715258|gb|ABR04055.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715286|gb|ABR04069.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715288|gb|ABR04070.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 705 bits (1819), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFTHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715116|gb|ABR03984.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 705 bits (1819), Expect = 0.0, Method: Composition-based stats.
Identities = 372/733 (50%), Positives = 521/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVKEQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715244|gb|ABR04048.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 525/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+ AS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEVASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714864|gb|ABR03858.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714928|gb|ABR03890.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 370/733 (50%), Positives = 525/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148715142|gb|ABR03997.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715256|gb|ABR04054.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715266|gb|ABR04059.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 529/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148715064|gb|ABR03958.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714966|gb|ABR03909.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714992|gb|ABR03922.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714994|gb|ABR03923.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714996|gb|ABR03924.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715002|gb|ABR03927.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715034|gb|ABR03943.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715036|gb|ABR03944.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715040|gb|ABR03946.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 523/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715264|gb|ABR04058.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 523/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLAQPNLTQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715280|gb|ABR04066.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSGMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715102|gb|ABR03977.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 374/733 (51%), Positives = 521/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAREAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGLESSLNTILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148714908|gb|ABR03880.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 371/733 (50%), Positives = 525/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A IKG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEIKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148714884|gb|ABR03868.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 371/733 (50%), Positives = 525/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A IKG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEIKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NFQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148715124|gb|ABR03988.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 375/736 (50%), Positives = 525/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSGMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714924|gb|ABR03888.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 370/733 (50%), Positives = 525/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148714910|gb|ABR03881.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 370/733 (50%), Positives = 526/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD+F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLTPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148715086|gb|ABR03969.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 375/736 (50%), Positives = 524/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRA TAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRALTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715018|gb|ABR03935.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 526/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQSGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|38142225|dbj|BAD00915.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 704 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 371/745 (49%), Positives = 526/745 (70%), Gaps = 7/745 (0%)
Query: 14 YVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTK 73
+ +R+R+ PA+NR+ VG+ + +L++ +F VF++NF VIIG+ SKFG DL +A K +
Sbjct: 10 FAIRNRKSPAENRKIVGKYISLLAVVLFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQIT 69
Query: 74 TIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDK 133
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 70 RTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKY 129
Query: 134 LGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYP 193
L + ++Y QL QVSFG KG GITY+ ++K + A +KG+ F + +R YP
Sbjct: 130 LDMDEAYVKEQLSQPNLTQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYP 189
Query: 194 NGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGT 253
NG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GT
Sbjct: 190 NGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGT 248
Query: 254 ETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRP 313
E ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRP
Sbjct: 249 EQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRP 308
Query: 314 TYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKV 373
T+N+DT EG + + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+
Sbjct: 309 TFNADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKI 366
Query: 374 GDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTR 433
D DW +NEG++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTR
Sbjct: 367 ADATTRDWDVNEGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTR 426
Query: 434 FGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADT 492
FG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DT
Sbjct: 427 FGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDT 486
Query: 493 NKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAV 552
N +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAV
Sbjct: 487 NNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAV 546
Query: 553 KSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNP 612
KSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P
Sbjct: 547 KSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATP 606
Query: 613 VLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVG 670
+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G G
Sbjct: 607 ILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTG 666
Query: 671 NKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSG 730
KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S
Sbjct: 667 TKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS- 725
Query: 731 TVTKQSVAAGEALSKTKKITITLGD 755
V KQ V A+ KKI +TLGD
Sbjct: 726 VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|148714896|gb|ABR03874.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 704 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 370/733 (50%), Positives = 525/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148715010|gb|ABR03931.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715196|gb|ABR04024.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 524/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPVENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714878|gb|ABR03865.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714882|gb|ABR03867.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714886|gb|ABR03869.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714892|gb|ABR03872.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 704 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 370/733 (50%), Positives = 525/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148715082|gb|ABR03967.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 704 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 527/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ DV DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSGMKVMTLASSIDNNTF-PSGEYFNSSEFKMADVTTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A ++
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAIK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDQVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715080|gb|ABR03966.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 703 bits (1815), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 525/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715178|gb|ABR04015.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715182|gb|ABR04017.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715246|gb|ABR04049.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 375/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTIGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715058|gb|ABR03955.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 375/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSGMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715072|gb|ABR03962.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 374/733 (51%), Positives = 522/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTIGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715050|gb|ABR03951.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 375/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAREAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSGMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715160|gb|ABR04006.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 730
Score = 702 bits (1812), Expect = 0.0, Method: Composition-based stats.
Identities = 373/734 (50%), Positives = 521/734 (70%), Gaps = 7/734 (0%)
Query: 25 NRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIY 84
NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIY
Sbjct: 1 NRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY 60
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y Q
Sbjct: 61 DRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQ 120
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 121 LAQPNLTQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGL 180
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK
Sbjct: 181 AQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGK 239
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 DVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-I 298
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 TEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVN 357
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
EG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 EGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQL 417
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE
Sbjct: 418 PADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKE 477
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 IVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEK 537
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +
Sbjct: 538 NGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKES 597
Query: 624 LD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 LNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEG 657
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 TNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNT 716
Query: 742 ALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 AIKNIKKIKLTLGD 730
>gi|148715008|gb|ABR03930.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 702 bits (1812), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 523/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG+ + +L++ +F VF++NF VIIG+ SKFG DL +A K + T V AKRGT
Sbjct: 1 AENRKIVGKYISLLAVVLFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMDETYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148714972|gb|ABR03912.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 702 bits (1811), Expect = 0.0, Method: Composition-based stats.
Identities = 372/736 (50%), Positives = 525/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+ AS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKETASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQSGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|157075965|gb|ABV10648.1| penicillin-binding protein 2X [Streptococcus gordonii str. Challis
substr. CH1]
Length = 751
Score = 702 bits (1811), Expect = 0.0, Method: Composition-based stats.
Identities = 385/760 (50%), Positives = 532/760 (70%), Gaps = 20/760 (2%)
Query: 7 LKHLFLNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQA 66
+K+ L Y +++R+ NR+ VG+NL +L++F+FFVF+INF ++IG+ KFGVDL +A
Sbjct: 1 MKNKILRYALKNRKTANMNRKQVGKNLSILTVFLFFVFLINFAILIGSGRKFGVDLMAEA 60
Query: 67 AKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKV 126
K Y K V AKRGTIYDRNGN +AEDST+Y++YAI+ Y S T E LYV+ SQ++ V
Sbjct: 61 KKVYQIKKTVQAKRGTIYDRNGNAIAEDSTTYNLYAIIDKKYKSATGEILYVEPSQYETV 120
Query: 127 ADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEA 186
A IL DKL I+ Y +QL + QV FG KG I Y+ D++K+ +DAG+KG++F+
Sbjct: 121 AQILHDKLDIETDYAKSQLSQEKLTQVYFGAKGNNIPYATMTDIKKSMEDAGVKGISFDT 180
Query: 187 TTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKD 246
+ SR YPN TFAS+F+G A+ +E +DGS SL G TGLE SL+ +L G DG YE+DK+
Sbjct: 181 SPSRSYPNETFASQFVGIAQ-LEENEDGSKSLRGSTGLEYSLDKILAGRDGLVTYERDKN 239
Query: 247 GNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEI 306
GN + G++ ++ +GK++YTT+S+ LQ++LET+MD F E+ KG SAT+V+AKTGE+
Sbjct: 240 GNIVPGSDQVSVATENGKDVYTTISSHLQSYLETRMDIFQEKVKGKFVSATLVSAKTGEV 299
Query: 307 LATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYS 366
LATTQRP++N+DT EG +K ++W LY++ YEPGSTMKV L++AI+N +F N TY
Sbjct: 300 LATTQRPSFNADTKEGLSKD-FNWSTLLYQSPYEPGSTMKVFTLASAIDNHTFPANETYF 358
Query: 367 NANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLY 426
N + ++ D I DW +N G+S G+T+++AQGF+YSSN+GM LE+ MGD W +YL +
Sbjct: 359 N-DEFQIEDTIIKDWGVNMGLSTGQTLTYAQGFAYSSNIGMARLEKKMGDDKWRDYLDKF 417
Query: 427 KFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQF 485
KFG+ TRFGM+GE G + +N V A SSFGQGI+VTQVQMLR FTAI+N+G+MLEP+F
Sbjct: 418 KFGVRTRFGMMGEDVGNLPDKNVVTTAMSSFGQGINVTQVQMLRGFTAIANDGVMLEPKF 477
Query: 486 IKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQV 545
I + D+ + R E+IG PVSK AA ETR YMI+VGTDP FGTL ++ G P+IQV
Sbjct: 478 ISAIYDSATNSARKGTNEIIGNPVSKTAAQETRKYMITVGTDPNFGTL--QTNGVPVIQV 535
Query: 546 GNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEP-KTWNNN 604
DVAVKSGTAQ+ E E + SVVAM P+EDP++IMYVTV++P + + +
Sbjct: 536 PGQDVAVKSGTAQIAAEAKDGGGYLEGEYIYSVVAMTPAEDPDFIMYVTVKQPEEKFYPD 595
Query: 605 FFATVVNPVLEEAMSMGAT---------LDTSVSEGSGKTEETSYQTGDIIGKTPGETAN 655
+ VVNP+LEEA++M T LD ++E +T + D K+PG A
Sbjct: 596 LWKEVVNPLLEEAVAMKDTLGLTTPTHVLDNVITETKYTMPKTKEKGKD---KSPGSYAE 652
Query: 656 TLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFA 715
LR+NLV PI+LG G+ I K+SV+A +N+ +N+Q+L++T+E ++PDMYGWTK+N TFA
Sbjct: 653 ELRRNLVQPIILGTGSSITKLSVEAGKNVASNQQVLLLTDELDDMPDMYGWTKENASTFA 712
Query: 716 KWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
KW IK+TYKG S V QSV A ++ K+ITITLG+
Sbjct: 713 KWLDIKVTYKGEGS-KVVGQSVKANTSIKNLKEITITLGE 751
>gi|148715278|gb|ABR04065.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 702 bits (1811), Expect = 0.0, Method: Composition-based stats.
Identities = 371/733 (50%), Positives = 524/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+++DT EG K
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK 299
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ DV DW +N
Sbjct: 300 D-FVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKMADVTTRDWDVNG 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ SV+
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715074|gb|ABR03963.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715192|gb|ABR04022.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715194|gb|ABR04023.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 701 bits (1810), Expect = 0.0, Method: Composition-based stats.
Identities = 376/736 (51%), Positives = 525/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKESSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+LI++++ E+PDMYGWTK ETFAKW I + ++G S TV KQ V A
Sbjct: 658 EGANLTPNQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIDLEFEGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148715206|gb|ABR04029.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 701 bits (1810), Expect = 0.0, Method: Composition-based stats.
Identities = 371/736 (50%), Positives = 525/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|38142251|dbj|BAD00928.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 701 bits (1810), Expect = 0.0, Method: Composition-based stats.
Identities = 372/747 (49%), Positives = 524/747 (70%), Gaps = 7/747 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F VF++NF VIIG+ SKFG DL +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++
Sbjct: 68 ITRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L + ++Y QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMDEAYVKEQLSQPNLTQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+N+DT EG + + W + LY++ YEPGS KVM L+++I+N +F P+ Y N++
Sbjct: 307 RPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMTLASSIDNNTF-PSGEYFNSSEF 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D DW +N G++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+P
Sbjct: 365 KIADATTRDWDVNAGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
DTN +VR ++KE++GKPVS+ AAS TR MI VGTDP +GT+YN G PII V +V
Sbjct: 485 DTNNQSVRKSQKEIVGKPVSEDAASLTRTNMILVGTDPLYGTMYNHYTGKPIITVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
AVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 AVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHFSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
P+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G
Sbjct: 605 TPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVG 664
Query: 669 VGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGK 728
G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G
Sbjct: 665 TGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSG 724
Query: 729 SGTVTKQSVAAGEALSKTKKITITLGD 755
S V KQ V A+ KKI +TLGD
Sbjct: 725 S-VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|148715056|gb|ABR03954.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 523/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSGVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715078|gb|ABR03965.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715140|gb|ABR03996.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 521/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRA TAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRALTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714938|gb|ABR03895.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 728
Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats.
Identities = 368/732 (50%), Positives = 525/732 (71%), Gaps = 7/732 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+PLQ+F+ETQMD+F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSPLQSFMETQMDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITI 751
A+ KKIT+
Sbjct: 717 NTAIKDIKKITL 728
>gi|148715052|gb|ABR03952.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 701 bits (1808), Expect = 0.0, Method: Composition-based stats.
Identities = 372/733 (50%), Positives = 519/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PV K+ AS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVPKEVASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715184|gb|ABR04018.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 730
Score = 701 bits (1808), Expect = 0.0, Method: Composition-based stats.
Identities = 374/734 (50%), Positives = 520/734 (70%), Gaps = 7/734 (0%)
Query: 25 NRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIY 84
NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIY
Sbjct: 1 NRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY 60
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y Q
Sbjct: 61 DRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQ 120
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 121 LSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGL 180
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK
Sbjct: 181 AQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGK 239
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 DVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-I 298
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 TKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVN 357
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 AGLTIGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQL 417
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE
Sbjct: 418 PADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKE 477
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 IVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEK 537
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +
Sbjct: 538 NGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKES 597
Query: 624 LD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 LNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEG 657
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 TNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNT 716
Query: 742 ALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 AIKNIKKIKLTLGD 730
>gi|148714976|gb|ABR03914.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 701 bits (1808), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715146|gb|ABR03999.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715152|gb|ABR04002.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 701 bits (1808), Expect = 0.0, Method: Composition-based stats.
Identities = 374/736 (50%), Positives = 521/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSGVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715158|gb|ABR04005.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 701 bits (1808), Expect = 0.0, Method: Composition-based stats.
Identities = 372/733 (50%), Positives = 519/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGLESSLNTILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ E FAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAEAFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715268|gb|ABR04060.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 701 bits (1808), Expect = 0.0, Method: Composition-based stats.
Identities = 372/736 (50%), Positives = 524/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714968|gb|ABR03910.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714970|gb|ABR03911.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148714998|gb|ABR03925.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715038|gb|ABR03945.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 701 bits (1808), Expect = 0.0, Method: Composition-based stats.
Identities = 371/733 (50%), Positives = 520/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715068|gb|ABR03960.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 700 bits (1807), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 524/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK E F+KW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148715226|gb|ABR04039.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715228|gb|ABR04040.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 700 bits (1806), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAREAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRA TAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRALTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715202|gb|ABR04027.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 730
Score = 699 bits (1805), Expect = 0.0, Method: Composition-based stats.
Identities = 370/734 (50%), Positives = 523/734 (71%), Gaps = 7/734 (0%)
Query: 25 NRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIY 84
NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIY
Sbjct: 1 NRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIY 60
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY Q
Sbjct: 61 DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQ 120
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 121 LSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGL 180
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK
Sbjct: 181 AQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGK 239
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTTLS+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 DVYTTLSSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-I 298
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 TEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVN 357
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
G++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 AGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQL 417
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE
Sbjct: 418 PADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKE 477
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 IVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEK 537
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +
Sbjct: 538 NGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKES 597
Query: 624 LD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 LNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEG 657
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 TNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNT 716
Query: 742 ALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 AIKNIKKIKLTLGD 730
>gi|148714978|gb|ABR03915.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 699 bits (1804), Expect = 0.0, Method: Composition-based stats.
Identities = 371/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715216|gb|ABR04034.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 699 bits (1804), Expect = 0.0, Method: Composition-based stats.
Identities = 371/733 (50%), Positives = 522/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715122|gb|ABR03987.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715204|gb|ABR04028.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 699 bits (1803), Expect = 0.0, Method: Composition-based stats.
Identities = 373/733 (50%), Positives = 519/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTIGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715046|gb|ABR03949.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715048|gb|ABR03950.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 699 bits (1803), Expect = 0.0, Method: Composition-based stats.
Identities = 373/733 (50%), Positives = 519/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAREAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSGMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148714990|gb|ABR03921.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715012|gb|ABR03932.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 698 bits (1802), Expect = 0.0, Method: Composition-based stats.
Identities = 370/733 (50%), Positives = 521/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715250|gb|ABR04051.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 698 bits (1802), Expect = 0.0, Method: Composition-based stats.
Identities = 371/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTELVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++GKPVS+ AS TR MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGKPVSEDTASLTRTNMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148714962|gb|ABR03907.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 698 bits (1801), Expect = 0.0, Method: Composition-based stats.
Identities = 370/736 (50%), Positives = 519/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG+ + +L++ +F VF++NF VIIG+ SKFG DL +A K + V AKRGT
Sbjct: 1 AENRKIVGKYISLLAVVLFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQITRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 LTKD-FVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715100|gb|ABR03976.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 697 bits (1800), Expect = 0.0, Method: Composition-based stats.
Identities = 370/733 (50%), Positives = 521/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMTIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSGVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715220|gb|ABR04036.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 697 bits (1800), Expect = 0.0, Method: Composition-based stats.
Identities = 369/733 (50%), Positives = 522/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQTPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715236|gb|ABR04044.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats.
Identities = 371/736 (50%), Positives = 523/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 598 DSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 658 EGKNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRA 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148715200|gb|ABR04026.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats.
Identities = 369/733 (50%), Positives = 522/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715092|gb|ABR03972.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 697 bits (1798), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG+ + +L++ +F VF++NF VIIG+ SKFG DL+ +A K + T V AKRGT
Sbjct: 1 AENRKIVGKYISLLAVVLFAVFLVNFAVIIGSGSKFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSGMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715060|gb|ABR03956.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 697 bits (1798), Expect = 0.0, Method: Composition-based stats.
Identities = 372/733 (50%), Positives = 520/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSGVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148714894|gb|ABR03873.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715150|gb|ABR04001.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715154|gb|ABR04003.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 696 bits (1797), Expect = 0.0, Method: Composition-based stats.
Identities = 372/733 (50%), Positives = 518/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSGVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715148|gb|ABR04000.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 371/736 (50%), Positives = 518/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG+ + +L++ +F VF++NF VIIG+ SKFG DL +A K + V AKRGT
Sbjct: 1 AENRKIVGKYISLLAVVLFAVFLVNFAVIIGSGSKFGTDLVKEAKKVHQITRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITKDFVWRDILYQSNYEPGSGMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715222|gb|ABR04037.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 694 bits (1792), Expect = 0.0, Method: Composition-based stats.
Identities = 369/733 (50%), Positives = 521/733 (71%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE I+++ ++GK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQISQKTVNGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS KVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAFKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715274|gb|ABR04063.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 694 bits (1791), Expect = 0.0, Method: Composition-based stats.
Identities = 369/733 (50%), Positives = 519/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+GKPVS+ AS TR MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGKPVSEDTASLTRTNMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148714946|gb|ABR03899.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 694 bits (1790), Expect = 0.0, Method: Composition-based stats.
Identities = 369/736 (50%), Positives = 519/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMNVFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P N++ +KV D DW
Sbjct: 300 LTKD-FVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PGGEVFNSSELKVADTTTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTVGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR +M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTHMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 538 EKNGGYLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715044|gb|ABR03948.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats.
Identities = 367/733 (50%), Positives = 520/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715252|gb|ABR04052.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 693 bits (1788), Expect = 0.0, Method: Composition-based stats.
Identities = 369/733 (50%), Positives = 520/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 717 IKDIKKITLTLGD 729
>gi|148715162|gb|ABR04007.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 692 bits (1786), Expect = 0.0, Method: Composition-based stats.
Identities = 365/736 (49%), Positives = 523/736 (71%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLN +L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNGILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P Y N++ +K+ DV DW
Sbjct: 300 LTKD-FVWRDILYQSNYEPGSPMKVMTLAAAIDNNTF-PGGEYFNSSELKIADVTTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F+QGF++SSNVGMT+LE+ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGGMMTFSQGFAHSSNVGMTLLEKKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N VNI QSSFGQGIS TQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++
Sbjct: 418 QLPADNIVNIGQSSFGQGISATQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KEV+G PVSK AAS TR +M+ VGTDP +GT+YN G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEVVGNPVSKDAASLTRTHMVLVGTDPVYGTMYNHKTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VGT + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A++M
Sbjct: 538 EKNGGYLVGTTNYIFSAVSMNPAENPDFILYVTVQQPEHFSGIQLGEFANPILERAVAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ ++ T +++Y I +PG+ A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 DSLNLQSTAKTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S TV KQ V
Sbjct: 658 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-TVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 717 NTAIKDIKKITLTLGD 732
>gi|148714900|gb|ABR03876.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 721
Score = 691 bits (1783), Expect = 0.0, Method: Composition-based stats.
Identities = 363/725 (50%), Positives = 517/725 (71%), Gaps = 7/725 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 LSKTK 747
+ K
Sbjct: 717 IKDIK 721
>gi|38142211|dbj|BAD00908.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|38142217|dbj|BAD00911.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 750
Score = 691 bits (1782), Expect = 0.0, Method: Composition-based stats.
Identities = 365/745 (48%), Positives = 517/745 (69%), Gaps = 7/745 (0%)
Query: 14 YVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTK 73
+ +++R+ PA+NR+ VG+ L +++ +F +F+ NF II + FG DL +A K + T
Sbjct: 10 FAIKNRKSPAKNRRIVGKYLSFVAVALFALFLANFAYIIAKGNIFGTDLVKEAKKVHQTT 69
Query: 74 TIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDK 133
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++
Sbjct: 70 RTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKY 129
Query: 134 LGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYP 193
L + ++Y QL QVSFG KG GITY+ ++ K AG++G+ F + +R YP
Sbjct: 130 LDMDEAYVKEQLAQPNLTQVSFGAKGNGITYANMMAIKNDLKTAGVEGIDFTTSPNRSYP 189
Query: 194 NGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGT 253
NG FAS F+G A+ EN+ DG+ LIG +GLE SLNS+L GTDG YEKD+ GN + GT
Sbjct: 190 NGQFASSFIGLAQLHENE-DGTKRLIGSSGLESSLNSILAGTDGIITYEKDRLGNIVPGT 248
Query: 254 ETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRP 313
E ++ +DGK++YTTLS+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRP
Sbjct: 249 EQASQHTVDGKDVYTTLSSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRP 308
Query: 314 TYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKV 373
T+N+DT +G K + W + LY++ YEPGS MKVM L++AI+N +F P Y N++ +K+
Sbjct: 309 TFNADTKDG-ITKDFVWRDILYQSNYEPGSAMKVMTLASAIDNNTF-PGGEYFNSSELKI 366
Query: 374 GDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTR 433
D I DW +N+G++ G M+F+QGF++SSNVGM++LEQ MGD W +YL+ +KFG+PTR
Sbjct: 367 ADATIRDWDVNDGLTTGGMMTFSQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTR 426
Query: 434 FGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADT 492
FG+ E +G + + N VNIA S+FGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + D
Sbjct: 427 FGLTDEYTGQLPADNIVNIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALYDP 486
Query: 493 NKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAV 552
N +VR ++KE++G PVSK AAS TR +M+ VGTDP +GT+YN S G P + V +VA+
Sbjct: 487 NDQSVRKSQKEIVGNPVSKAAASSTREHMVMVGTDPVYGTMYNHSTGKPNVNVPGQNVAL 546
Query: 553 KSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNP 612
KSGTAQ+ DEK G Y G + SVV+M P+E+P++I+YVTVQ+P+ ++ NP
Sbjct: 547 KSGTAQIADEKNGGYLTGETNYIFSVVSMHPAENPDFILYVTVQQPEHYSGVQLGEFANP 606
Query: 613 VLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVG 670
+LE A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G G
Sbjct: 607 ILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTG 666
Query: 671 NKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSG 730
KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S
Sbjct: 667 TKIKESSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS- 725
Query: 731 TVTKQSVAAGEALSKTKKITITLGD 755
V KQ V A+ KKI +TLGD
Sbjct: 726 VVQKQDVRTNTAIKNIKKIKLTLGD 750
>gi|148714898|gb|ABR03875.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 720
Score = 690 bits (1780), Expect = 0.0, Method: Composition-based stats.
Identities = 362/721 (50%), Positives = 516/721 (71%), Gaps = 7/721 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 299 EDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 418 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 538 GGYLVGVTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 L 743
+
Sbjct: 717 I 717
>gi|148715134|gb|ABR03993.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715174|gb|ABR04013.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715212|gb|ABR04032.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715214|gb|ABR04033.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 689 bits (1779), Expect = 0.0, Method: Composition-based stats.
Identities = 368/736 (50%), Positives = 522/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY++ YEPGS MKVM L+AAI+N +F P N++ +KV DV DW
Sbjct: 300 LTKD-FVWRDILYQSNYEPGSPMKVMTLAAAIDNNTF-PGGEVFNSSELKVADVTTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTGGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+I QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N +VR ++
Sbjct: 418 QLPADNIVSIGQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ D
Sbjct: 478 KEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VGT + + S V+M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGTTDYIFSAVSMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDQVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGKNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715130|gb|ABR03991.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 712
Score = 689 bits (1778), Expect = 0.0, Method: Composition-based stats.
Identities = 363/715 (50%), Positives = 513/715 (71%), Gaps = 7/715 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVND 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDV 711
>gi|148715000|gb|ABR03926.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 712
Score = 688 bits (1776), Expect = 0.0, Method: Composition-based stats.
Identities = 363/715 (50%), Positives = 510/715 (71%), Gaps = 7/715 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PV K+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVPKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDV 711
>gi|148715076|gb|ABR03964.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 712
Score = 687 bits (1774), Expect = 0.0, Method: Composition-based stats.
Identities = 364/715 (50%), Positives = 513/715 (71%), Gaps = 7/715 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T IV AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRIVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
K + W + LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 KDFVWRDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTIGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 598 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V
Sbjct: 658 NLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDV 711
>gi|148715270|gb|ABR04061.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 687 bits (1774), Expect = 0.0, Method: Composition-based stats.
Identities = 365/733 (49%), Positives = 517/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG F S F+G A
Sbjct: 121 SQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFTSSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE I+++ ++GK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQISQKTVNGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMDAFQEKLKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS KVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAFKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VGT + + S V+M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGTTDYIFSAVSMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ +
Sbjct: 598 NLQSPAKNLDQVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715188|gb|ABR04020.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 715
Score = 686 bits (1771), Expect = 0.0, Method: Composition-based stats.
Identities = 366/718 (50%), Positives = 513/718 (71%), Gaps = 7/718 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGT
Sbjct: 1 AENRRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKESSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
N+ N+Q+LI++++ E+PDMYGWTK ETFAKW I + ++G S TV KQ V
Sbjct: 658 EGANLTPNQQVLILSDKAEEVPDMYGWTKATAETFAKWLNIDLEFEGSGS-TVQKQDV 714
>gi|148715262|gb|ABR04057.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 732
Score = 686 bits (1770), Expect = 0.0, Method: Composition-based stats.
Identities = 366/736 (49%), Positives = 517/736 (70%), Gaps = 7/736 (0%)
Query: 23 AQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGT 82
A+NR+ VG+ + + ++ +F +F++NF VIIG+ SKFG DL +A K + T V AKRGT
Sbjct: 1 AENRRIVGKYISLSAVVLFAIFLVNFAVIIGSGSKFGADLVKEAKKVHQTTRTVPAKRGT 60
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y
Sbjct: 61 IYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVK 120
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+
Sbjct: 121 EQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFI 180
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +D
Sbjct: 181 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVD 239
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 240 GKDVYTTISSTLQSFMETQMNAFQEKIKGKYMTATLVSAKTGEILATTQRPTFDADTKEG 299
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
K + W + LY+ YEPGS KVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 300 LTKD-FVWRDILYQGNYEPGSAFKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 357
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+NEG++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 358 VNEGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 417
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 418 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 477
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 478 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 537
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 538 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMK 597
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 ESLNLQSPAKNLDQVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 657
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
+N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 EGKNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRT 716
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 717 NTAIKNIKKIKLTLGD 732
>gi|148715176|gb|ABR04014.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
gi|148715232|gb|ABR04042.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 685 bits (1768), Expect = 0.0, Method: Composition-based stats.
Identities = 366/733 (49%), Positives = 519/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K
Sbjct: 240 VYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK 299
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ W + LY++ YEPGS MKVM L+AAI+N +F P N++ +KV DV DW +NE
Sbjct: 300 D-FVWRDILYQSNYEPGSPMKVMTLAAAIDNNTF-PGGEVFNSSELKVADVTTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+I QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N +VR ++KE+
Sbjct: 418 ADNIVSIGQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VGT + + S V+M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGTTDYIFSAVSMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ +
Sbjct: 598 NLQSPAKNLDQVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715230|gb|ABR04041.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 684 bits (1766), Expect = 0.0, Method: Composition-based stats.
Identities = 364/733 (49%), Positives = 519/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K
Sbjct: 240 VYTTISSTLQSFMETQMNAFQEKIKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK 299
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ W + LY++ YEPGS MKVM L+AAI+N +F P N++ +KV DV DW +NE
Sbjct: 300 D-FVWRDILYQSNYEPGSPMKVMTLAAAIDNNTF-PGGEVFNSSELKVADVTTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVGMT+LE+ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTVGGMMTFSQGFAHSSNVGMTLLEKKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+I QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N +VR ++KE+
Sbjct: 418 ADNIVSIGQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VGT + + S V+M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGTTDYIFSAVSMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ +
Sbjct: 598 NLQSPAKNLDQVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715272|gb|ABR04062.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 729
Score = 682 bits (1761), Expect = 0.0, Method: Composition-based stats.
Identities = 364/733 (49%), Positives = 518/733 (70%), Gaps = 7/733 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+ SY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDAISYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K
Sbjct: 240 VYTTISSTLQSFMETQMNAFQEKIKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK 299
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ W + LY++ YEPGS MKVM L+AAI+N +F P N++ +KV DV DW +NE
Sbjct: 300 D-FVWRDILYQSNYEPGSPMKVMTLAAAIDNNTF-PGGEVFNSSELKVADVTTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVGMT+LE+ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTVGGMMTFSQGFAHSSNVGMTLLEKKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+I QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N +VR ++KE+
Sbjct: 418 ADNIVSIGQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VGT + + S V+M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGTTDYIFSAVSMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ +
Sbjct: 598 NLQSPAKNLDQVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRTNTA 716
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 717 IKNIKKIKLTLGD 729
>gi|148715290|gb|ABR04071.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 718
Score = 676 bits (1744), Expect = 0.0, Method: Composition-based stats.
Identities = 362/721 (50%), Positives = 511/721 (70%), Gaps = 7/721 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 240 VYTTISSTLQSFMETQMNVFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 298
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 299 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 358 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 418 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 478 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGSTNYIFSSVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI+ S + +
Sbjct: 598 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKNSSAEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 NLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 716
Query: 743 L 743
+
Sbjct: 717 I 717
>gi|148715208|gb|ABR04030.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 712
Score = 674 bits (1740), Expect = 0.0, Method: Composition-based stats.
Identities = 354/715 (49%), Positives = 509/715 (71%), Gaps = 7/715 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLN +L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNGILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K
Sbjct: 240 VYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK 299
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ W + LY++ YEPGS MKVM L+AAI+N +F P Y N++ +K+ DV DW +NE
Sbjct: 300 D-FVWRDILYQSNYEPGSPMKVMTLAAAIDNNTF-PGGEYFNSSELKIADVTTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVGMT+LE+ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTGGGMMTFSQGFAHSSNVGMTLLEKKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNI QSSFGQGIS TQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KEV
Sbjct: 418 ADNIVNIGQSSFGQGISATQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEV 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR +M+ VGTDP +GT+YN G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTHMVLVGTDPVYGTMYNHKTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VGT + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A++M +L
Sbjct: 538 GGYLVGTTNYIFSAVSMNPAENPDFILYVTVQQPEHFSGIQLGEFANPILERAVAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ ++ T +++Y I +PG+ A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSTAKTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S TV KQ V
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-TVQKQDV 711
>gi|148715260|gb|ABR04056.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 712
Score = 672 bits (1733), Expect = 0.0, Method: Composition-based stats.
Identities = 357/715 (49%), Positives = 509/715 (71%), Gaps = 7/715 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F VF++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAVFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K
Sbjct: 240 VYTTISSTLQSFMETQMNAFQEKIKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK 299
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ W + LY++ YEPGS MKVM L+AAI+N +F P N++ +KV DV DW +NE
Sbjct: 300 D-FVWRDILYQSNYEPGSPMKVMTLAAAIDNNTF-PGGEVFNSSELKVADVTTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVGMT+LE+ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTVGGMMTFSQGFAHSSNVGMTLLEKKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+I QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N +VR ++KE+
Sbjct: 418 ADNIVSIGQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VGT + + S V+M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 538 GGYLVGTTDYIFSAVSMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMKESL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ +
Sbjct: 598 NLQSPAKNLDQVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGK 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 658 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDV 711
>gi|148715198|gb|ABR04025.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 717
Score = 671 bits (1731), Expect = 0.0, Method: Composition-based stats.
Identities = 356/721 (49%), Positives = 511/721 (70%), Gaps = 7/721 (0%)
Query: 26 RQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYD 85
R+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K + T V AKRGTIYD
Sbjct: 1 RRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYD 60
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 61 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 120
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 121 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 180
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 181 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 239
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K
Sbjct: 240 VYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTK 299
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ W + LY++ YEPGS MKVM L+AAI+N +F P N++ +KV DV DW +NE
Sbjct: 300 D-FVWRDILYQSNYEPGSPMKVMTLAAAIDNNTF-PGGEVFNSSELKVADVTTRDWDVNE 357
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 358 GLTVGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 417
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+I QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N +VR ++KE+
Sbjct: 418 ADNIVSIGQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEI 477
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 478 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 537
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VGT + S V+M P+E+P++I+YVTVQ+P+ + NP+LE A++M +L
Sbjct: 538 GGYLVGTTNYIFSAVSMNPAENPDFILYVTVQQPEHYAGIQLGEFANPILERAVAMKDSL 597
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ ++ T ++ Y I +PG+ A LR+N+V PIV+G G KI++ SV+
Sbjct: 598 NLQSTAKTLDHVTNQSVYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVEEGT 657
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
++ N+Q+L+++++ E+PDMYGWTK E F+KW I++ ++G S TV KQ V A A
Sbjct: 658 DLAPNQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSGS-TVQKQDVRANTA 716
Query: 743 L 743
+
Sbjct: 717 I 717
>gi|8569396|pdb|1QME|A Chain A, Penicillin-Binding Protein 2x (Pbp-2x)
gi|8569397|pdb|1QMF|A Chain A, Penicillin-Binding Protein 2x (Pbp-2x) Acyl-Enzyme Complex
Length = 702
Score = 669 bits (1727), Expect = 0.0, Method: Composition-based stats.
Identities = 356/706 (50%), Positives = 502/706 (71%), Gaps = 7/706 (0%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 GTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSAT 60
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 GKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKK 120
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
+ A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 ELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSIL 179
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
GTDG YEKD+ GN + GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG
Sbjct: 180 AGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGK 239
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
+AT+V+AKTGEILATTQRPT+++DT EG + + W + LY++ YEPGSTMKVM+L+A
Sbjct: 240 YMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAA 298
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
AI+N +F P N++ +K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ
Sbjct: 299 AIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQ 357
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAF 471
MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAF
Sbjct: 358 KMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAF 417
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAI+N+G+MLEP+FI + D N T R ++KE++G PVSK AAS TR M+ VGTDP +G
Sbjct: 418 TAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYG 477
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIM 591
T+YN S G P + V +VA+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+
Sbjct: 478 TMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFIL 537
Query: 592 YVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKT 649
YVTVQ+P+ ++ NP+LE A +M +L+ T+ ++++ Y + +
Sbjct: 538 YVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDIS 597
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PG+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+
Sbjct: 598 PGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKE 657
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
ET AKW I++ ++G S TV KQ V A A+ KKIT+TLGD
Sbjct: 658 TAETLAKWLNIELEFQGSGS-TVQKQDVRANTAIKDIKKITLTLGD 702
>gi|148715240|gb|ABR04046.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 703
Score = 669 bits (1725), Expect = 0.0, Method: Composition-based stats.
Identities = 359/707 (50%), Positives = 499/707 (70%), Gaps = 7/707 (0%)
Query: 52 IGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSP 111
IGT ++FG DL+ +A K + T IV AKRGTIYDRNG +AED+TSY++YA++ +Y S
Sbjct: 1 IGTGTRFGTDLAKEAKKVHQTTRIVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSA 60
Query: 112 TREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLE 171
T + LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++
Sbjct: 61 TGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIK 120
Query: 172 KTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSL 231
K + A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+
Sbjct: 121 KELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSI 179
Query: 232 LTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKG 291
L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+S+ LQ+F+ETQMD F+E+ KG
Sbjct: 180 LAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQMDAFLEKVKG 239
Query: 292 INASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLS 351
+AT+V+AKTGEILATTQRPT+N+DT EG K + W + LY++ YEPGS MKVM L+
Sbjct: 240 KYMTATLVSAKTGEILATTQRPTFNADTKEG-ITKDFVWRDILYQSNYEPGSAMKVMTLA 298
Query: 352 AAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLE 411
AAI+N +F P+ Y N++ K+ D DW +N G++ G M+F QGF++SSNVGM++LE
Sbjct: 299 AAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNAGLTTGGMMTFLQGFAHSSNVGMSLLE 357
Query: 412 QAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRA 470
Q MGD W +YL +KFG+PTRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRA
Sbjct: 358 QKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRA 417
Query: 471 FTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEF 530
FTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV K+AAS TRN+MI VGTDP +
Sbjct: 418 FTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVPKEAASTTRNHMILVGTDPLY 477
Query: 531 GTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYI 590
GT+YN G PII V +VAVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I
Sbjct: 478 GTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFI 537
Query: 591 MYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGK 648
+YVTVQ+P+ ++ P+LE A +M +L+ + T E+SY I
Sbjct: 538 LYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDI 597
Query: 649 TPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTK 708
+PGE A LR+N+V PIV+G G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K
Sbjct: 598 SPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKK 657
Query: 709 KNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
+ ETFAKW I++ ++G S V KQ V A+ KKI +TLGD
Sbjct: 658 ETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIKKIKLTLGD 703
>gi|42543579|pdb|1RP5|A Chain A, Pbp2x From Streptococcus Pneumoniae Strain 5259 With
Reduced Susceptibility To Beta-Lactam Antibiotics
gi|42543580|pdb|1RP5|B Chain B, Pbp2x From Streptococcus Pneumoniae Strain 5259 With
Reduced Susceptibility To Beta-Lactam Antibiotics
gi|38091082|emb|CAE53270.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 702
Score = 669 bits (1725), Expect = 0.0, Method: Composition-based stats.
Identities = 353/706 (50%), Positives = 505/706 (71%), Gaps = 7/706 (0%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 GTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSAT 60
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 GKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKK 120
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
+ A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 ELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSIL 179
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
GTDG YEKD+ GN + GTE ++++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG
Sbjct: 180 AGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSPLQSFMETQMDAFQEKVKGK 239
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
+AT+V+AKTGEILATTQRPT+++DT EG + + W + LY++ YEPGSTMKVM+L+A
Sbjct: 240 YMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAA 298
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
AI+N +F P N++ +K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ
Sbjct: 299 AIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQ 357
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAF 471
MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIA S+FGQGISVTQ QMLRAF
Sbjct: 358 KMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAMSAFGQGISVTQTQMLRAF 417
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAI+N+G+MLEP+FI + D N +VR ++KE++G PVSK+AAS TR++M+ VGTDP +G
Sbjct: 418 TAIANDGVMLEPKFISALYDPNDQSVRKSQKEIVGNPVSKEAASVTRDHMVMVGTDPTYG 477
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIM 591
T+YN S G + V +VA+KSGTA++ DEK G Y G+ + SVV+M P+E+P++I+
Sbjct: 478 TMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLTGSTNNIFSVVSMHPAENPDFIL 537
Query: 592 YVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKT 649
YVTVQ+P+ ++ NP+LE A +M +L+ T+ ++++ Y + +
Sbjct: 538 YVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQTTAKALEQVSQQSPYPMPSVKDIS 597
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PG+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+
Sbjct: 598 PGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKE 657
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
ETFAKW I++ ++G S TV KQ V A A+ KKI +TLGD
Sbjct: 658 TAETFAKWLNIELEFEGSGS-TVQKQDVRANTAIKDIKKIKLTLGD 702
>gi|148715234|gb|ABR04043.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 703
Score = 669 bits (1725), Expect = 0.0, Method: Composition-based stats.
Identities = 358/707 (50%), Positives = 498/707 (70%), Gaps = 7/707 (0%)
Query: 52 IGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSP 111
IGT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S
Sbjct: 1 IGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSA 60
Query: 112 TREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLE 171
T + LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++
Sbjct: 61 TGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIK 120
Query: 172 KTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSL 231
K + A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+
Sbjct: 121 KELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSI 179
Query: 232 LTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKG 291
L GTDG YEKD+ GN + GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG
Sbjct: 180 LAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKG 239
Query: 292 INASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLS 351
+AT+V+AKTGEILATTQRPT+N+DT EG + + W + LY++ YEPGS MKVM L+
Sbjct: 240 KYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLA 298
Query: 352 AAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLE 411
AAI+N +F P+ Y N++ K+ D DW +N G++ G M+F QGF++SSNVGM++LE
Sbjct: 299 AAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNAGLTTGGMMTFLQGFAHSSNVGMSLLE 357
Query: 412 QAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRA 470
Q MGD W +YL +KFG+PTRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRA
Sbjct: 358 QKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRA 417
Query: 471 FTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEF 530
FTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV K+AAS TRN+MI VGTDP +
Sbjct: 418 FTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVPKEAASTTRNHMILVGTDPLY 477
Query: 531 GTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYI 590
GT+YN G PII V +VAVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I
Sbjct: 478 GTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFI 537
Query: 591 MYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGK 648
+YVTVQ+P+ ++ P+LE A +M +L+ + T E+SY I
Sbjct: 538 LYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDI 597
Query: 649 TPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTK 708
+PGE A LR+N+V PIV+G G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K
Sbjct: 598 SPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKK 657
Query: 709 KNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
+ ETFAKW I++ ++G S V KQ V A+ KKI +TLGD
Sbjct: 658 ETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIKKIKLTLGD 703
>gi|30519792|emb|CAD90770.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 702
Score = 667 bits (1721), Expect = 0.0, Method: Composition-based stats.
Identities = 357/706 (50%), Positives = 500/706 (70%), Gaps = 7/706 (0%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 GTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSAT 60
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 GKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKK 120
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
+ A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 ELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSIL 179
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
GTDG YEKD+ GN + GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG
Sbjct: 180 AGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGK 239
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
+AT+V+AKTGEILATTQRPT+N+DT EG + + W + LY++ YEPGS MKVM L++
Sbjct: 240 YMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLAS 298
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
+I+N +F P+ Y N++ K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ
Sbjct: 299 SIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQ 357
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAF 471
MGD W +YL +KFG+PTRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAF
Sbjct: 358 KMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAF 417
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAI+N+G+MLEP+FI + DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +G
Sbjct: 418 TAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYG 477
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIM 591
T+YN G PII V +VAVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+
Sbjct: 478 TMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFIL 537
Query: 592 YVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKT 649
YVTVQ+P+ ++ P+LE A +M +L+ + T E+SY I +
Sbjct: 538 YVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDIS 597
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PGE A LR+N+V PIV+G G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+
Sbjct: 598 PGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKE 657
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
ETFAKW I++ ++G S V KQ V A+ KKI +TLGD
Sbjct: 658 TAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIKKIKLTLGD 702
>gi|148714988|gb|ABR03920.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 702
Score = 667 bits (1720), Expect = 0.0, Method: Composition-based stats.
Identities = 357/706 (50%), Positives = 497/706 (70%), Gaps = 7/706 (0%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 GTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSAT 60
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 GKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKK 120
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
+ A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 ELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSIL 179
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
GTDG YEKD+ GN + GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG
Sbjct: 180 AGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGK 239
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
+AT+V+AKTGEILATTQRPT+N+DT EG + + W + LY++ YEPGS MKVM L+A
Sbjct: 240 YMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLAA 298
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
AI+N +F P+ Y N++ K+ D DW +N G++ G M+F QGF++SSNVGM++LEQ
Sbjct: 299 AIDNNTF-PSGEYFNSSEFKIADATTRDWDVNAGLTTGGMMTFLQGFAHSSNVGMSLLEQ 357
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAF 471
MGD W +YL +KFG+PTRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAF
Sbjct: 358 KMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAF 417
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAI+N+G+MLEP+FI + DTN +VR ++KE++G PV K+AAS TRN+MI VGTDP +G
Sbjct: 418 TAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVPKEAASTTRNHMILVGTDPLYG 477
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIM 591
T+YN G PII V +VAVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+
Sbjct: 478 TMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFIL 537
Query: 592 YVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKT 649
YVTVQ+P+ ++ P+LE A +M +L+ + T E+SY I +
Sbjct: 538 YVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDIS 597
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PGE A LR+N+V PIV+G G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+
Sbjct: 598 PGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKE 657
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
ETFAKW I++ ++G S V KQ V A+ KKI +TLGD
Sbjct: 658 TAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIKKIKLTLGD 702
>gi|37927671|pdb|1PYY|A Chain A, Double Mutant Pbp2x T338aM339F FROM STREPTOCOCCUS
Pneumoniae Strain R6 At 2.4 A Resolution
Length = 702
Score = 666 bits (1719), Expect = 0.0, Method: Composition-based stats.
Identities = 354/706 (50%), Positives = 500/706 (70%), Gaps = 7/706 (0%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 GTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSAT 60
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 GKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKK 120
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
+ A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 ELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSIL 179
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
GTDG YEKD+ GN + GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG
Sbjct: 180 AGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGK 239
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
+AT+V+AKTGEILATTQRPT+++DT EG + + W + LY++ YEPGS KVM+L+A
Sbjct: 240 YMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMMLAA 298
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
AI+N +F P N++ +K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ
Sbjct: 299 AIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQ 357
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAF 471
MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAF
Sbjct: 358 KMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAF 417
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAI+N+G+MLEP+FI + D N T R ++KE++G PVSK AAS TR M+ VGTDP +G
Sbjct: 418 TAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYG 477
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIM 591
T+YN S G P + V +VA+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+
Sbjct: 478 TMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFIL 537
Query: 592 YVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKT 649
YVTVQ+P+ ++ NP+LE A +M +L+ T+ ++++ Y + +
Sbjct: 538 YVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDIS 597
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PG+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+
Sbjct: 598 PGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKE 657
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
ET AKW I++ ++G S TV KQ V A A+ KKIT+TLGD
Sbjct: 658 TAETLAKWLNIELEFQGSGS-TVQKQDVRANTAIKDIKKITLTLGD 702
>gi|53748611|emb|CAD90771.2| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 702
Score = 665 bits (1717), Expect = 0.0, Method: Composition-based stats.
Identities = 355/706 (50%), Positives = 498/706 (70%), Gaps = 7/706 (0%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 GTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSAT 60
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 GKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMAIKK 120
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
KDA ++G+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 DLKDASVEGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSIL 179
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
G DG YEKD+ GN + GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG
Sbjct: 180 AGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGK 239
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
+AT+V+AKTGEILATTQRPT+N+DT EG + + W + LY++ YEPGS KVM+L++
Sbjct: 240 YMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAFKVMMLAS 298
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
+I+N +F P+ Y N++ K+ D DW +N G++ G M+F QGF++SSNVG ++LEQ
Sbjct: 299 SIDNNTF-PSGEYFNSSEFKIADATTRDWDVNAGLTTGGMMTFLQGFAHSSNVGTSLLEQ 357
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAF 471
MGD W +YL +KFG+PTRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAF
Sbjct: 358 KMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAF 417
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAI+N+G+MLEP+FI + DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +G
Sbjct: 418 TAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYG 477
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIM 591
T+YN G PII V +VAVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+
Sbjct: 478 TMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFIL 537
Query: 592 YVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKT 649
YVTVQ+P+ ++ P+LE A +M +L+ + T E+SY I +
Sbjct: 538 YVTVQQPEHFSGIQLGEFATPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDIS 597
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PGE A LR+N+V PIV+G G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+
Sbjct: 598 PGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKE 657
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKITITLGD 755
ETFAKW I++ ++G S V KQ V A+ KKI +TLGD
Sbjct: 658 TAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIKKIKLTLGD 702
>gi|148714922|gb|ABR03887.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 689
Score = 656 bits (1693), Expect = 0.0, Method: Composition-based stats.
Identities = 349/693 (50%), Positives = 493/693 (71%), Gaps = 7/693 (1%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 GTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSAT 60
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 GKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKK 120
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
+ A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 ELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSIL 179
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
GTDG YEKD+ GN + GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG
Sbjct: 180 AGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGK 239
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
+AT+V+AKTGEILATTQRPT+++DT EG + + W + LY++ YEPGSTMKVM+L+A
Sbjct: 240 YMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAA 298
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
AI+N +F P N++ +K+ D I DW +NEG++ GRTM+F+QGF++SSNVGMT+LEQ
Sbjct: 299 AIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGGRTMTFSQGFAHSSNVGMTLLEQ 357
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAF 471
MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAF
Sbjct: 358 KMGDTTWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAF 417
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAI+N+G+MLEP+FI + D N T R ++KE++G PVSK AAS TR M+ VGTDP +G
Sbjct: 418 TAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYG 477
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIM 591
T+YN S G P + V +VA+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+
Sbjct: 478 TMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFIL 537
Query: 592 YVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKT 649
YVTVQ+P+ ++ NP+LE A +M +L+ T+ ++++ Y + +
Sbjct: 538 YVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDIS 597
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PG+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+
Sbjct: 598 PGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKE 657
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
ET AKW I++ ++G S TV KQ V A A
Sbjct: 658 TAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 689
>gi|148714984|gb|ABR03918.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 686
Score = 656 bits (1692), Expect = 0.0, Method: Composition-based stats.
Identities = 347/689 (50%), Positives = 491/689 (71%), Gaps = 7/689 (1%)
Query: 52 IGTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSP 111
IGT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S
Sbjct: 1 IGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSA 60
Query: 112 TREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLE 171
T + LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++
Sbjct: 61 TGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIK 120
Query: 172 KTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSL 231
K + A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+
Sbjct: 121 KELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSI 179
Query: 232 LTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKG 291
L GTDG YEKD+ GN + GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG
Sbjct: 180 LAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKG 239
Query: 292 INASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLS 351
+AT+V+AKTGEILATTQRPT+++DT EG + + W + LY++ YEPGSTMKVM+L+
Sbjct: 240 KYMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLA 298
Query: 352 AAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLE 411
AAI+N +F P N++ +K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LE
Sbjct: 299 AAIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLE 357
Query: 412 QAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRA 470
Q MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RA
Sbjct: 358 QKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRA 417
Query: 471 FTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEF 530
FTAI+N+G+MLEP+FI + D N T R ++KE++G PVSK AAS TR M+ VGTDP +
Sbjct: 418 FTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVY 477
Query: 531 GTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYI 590
GT+YN S G P + V +VA+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I
Sbjct: 478 GTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVTDYIFSAVSMSPAENPDFI 537
Query: 591 MYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGK 648
+YVTVQ+P+ ++ NP+LE A +M +L+ T+ ++++ Y +
Sbjct: 538 LYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDI 597
Query: 649 TPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTK 708
+PG+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK
Sbjct: 598 SPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKVEEVPDMYGWTK 657
Query: 709 KNVETFAKWKGIKITYKGGKSGTVTKQSV 737
+ ET AKW I++ ++G S TV KQ V
Sbjct: 658 ETAETLAKWLNIELEFQGSGS-TVQKQDV 685
>gi|148714960|gb|ABR03906.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 686
Score = 655 bits (1689), Expect = 0.0, Method: Composition-based stats.
Identities = 349/688 (50%), Positives = 490/688 (71%), Gaps = 7/688 (1%)
Query: 53 GTDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPT 112
GT ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 GTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSAT 60
Query: 113 REKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEK 172
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 GKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITYANMMSIKK 120
Query: 173 TFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLL 232
+ A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 ELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSIL 179
Query: 233 TGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGI 292
GTDG YEKD+ GN + GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG
Sbjct: 180 AGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGK 239
Query: 293 NASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSA 352
+AT+V+AKTGEILATTQRPT+N+DT EG + + W + LY++ YEPGS MKVM L++
Sbjct: 240 YMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLAS 298
Query: 353 AINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQ 412
+I+N +F P+ Y N++ K+ D DW +N+G++ G M+F QGF++SSNVGM++LEQ
Sbjct: 299 SIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQ 357
Query: 413 AMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAF 471
MGD W +YL +KFG+PTRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAF
Sbjct: 358 KMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAF 417
Query: 472 TAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFG 531
TAI+N+G+MLEP+FI + DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +G
Sbjct: 418 TAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYG 477
Query: 532 TLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIM 591
T+YN G PII V +VAVKSGTAQ+ DEK G Y VG+ + SVV M P+E+P++I+
Sbjct: 478 TMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGSTNYIFSVVTMNPAENPDFIL 537
Query: 592 YVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKT 649
YVTVQ+P+ ++ P+LE A +M +L+ + T E+SY I +
Sbjct: 538 YVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDIS 597
Query: 650 PGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKK 709
PGE A LR+N+V PIV+G G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+
Sbjct: 598 PGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKE 657
Query: 710 NVETFAKWKGIKITYKGGKSGTVTKQSV 737
ETFAKW I++ ++G S V KQ V
Sbjct: 658 TAETFAKWLDIELEFEGSGS-VVQKQDV 684
>gi|148715098|gb|ABR03975.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 681
Score = 654 bits (1687), Expect = 0.0, Method: Composition-based stats.
Identities = 347/685 (50%), Positives = 489/685 (71%), Gaps = 7/685 (1%)
Query: 58 FGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLY 117
FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LY
Sbjct: 1 FGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILY 60
Query: 118 VQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDA 177
V+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K + A
Sbjct: 61 VEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAA 120
Query: 178 GIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDG 237
+KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG
Sbjct: 121 EVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDG 179
Query: 238 EAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASAT 297
YEKD+ GN + GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT
Sbjct: 180 IITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTAT 239
Query: 298 VVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNG 357
+V+AKTGEILATTQRPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N
Sbjct: 240 LVSAKTGEILATTQRPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNN 298
Query: 358 SFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDK 417
+F P N++ +K+ D I DW +NEG++ GRTM+F+QGF++SSNVGMT+LEQ MGD
Sbjct: 299 TF-PGGEVFNSSELKIADATIRDWDVNEGLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDA 357
Query: 418 VWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISN 476
W +YL+ +KFG+PTRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N
Sbjct: 358 TWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIAN 417
Query: 477 NGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNK 536
+G+MLEP+FI + D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN
Sbjct: 418 DGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNH 477
Query: 537 SEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQ 596
S G P + V +VA+KSGTAQ+ DEK G Y VG + + SVV+M P+E+P++I+YVTVQ
Sbjct: 478 STGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSVVSMSPAENPDFILYVTVQ 537
Query: 597 EPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETA 654
+P+ ++ NP+LE A +M +L+ T+ ++++ Y + +PG+ A
Sbjct: 538 QPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLA 597
Query: 655 NTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETF 714
LR+NLV PIV+G G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET
Sbjct: 598 EELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETL 657
Query: 715 AKWKGIKITYKGGKSGTVTKQSVAA 739
AKW I++ ++G S TV KQ V A
Sbjct: 658 AKWLNIELEFQGSGS-TVQKQDVRA 681
>gi|16974968|pdb|1K25|A Chain A, Pbp2x From A Highly Penicillin-Resistant Streptococcus
Pneumoniae Clinical Isolate
gi|16974969|pdb|1K25|B Chain B, Pbp2x From A Highly Penicillin-Resistant Streptococcus
Pneumoniae Clinical Isolate
gi|16974970|pdb|1K25|C Chain C, Pbp2x From A Highly Penicillin-Resistant Streptococcus
Pneumoniae Clinical Isolate
gi|16974971|pdb|1K25|D Chain D, Pbp2x From A Highly Penicillin-Resistant Streptococcus
Pneumoniae Clinical Isolate
Length = 685
Score = 653 bits (1684), Expect = 0.0, Method: Composition-based stats.
Identities = 348/683 (50%), Positives = 485/683 (71%), Gaps = 7/683 (1%)
Query: 76 VAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLG 135
V AKRGTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L
Sbjct: 7 VPAKRGTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLD 66
Query: 136 IKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNG 195
+++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG
Sbjct: 67 MEESYVREQLSQPNLKQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNG 126
Query: 196 TFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTET 255
FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE
Sbjct: 127 QFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTEL 185
Query: 256 ITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTY 315
++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+
Sbjct: 186 VSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTF 245
Query: 316 NSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGD 375
N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ +K+ D
Sbjct: 246 NADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSELKIAD 303
Query: 376 VEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFG 435
DW +NEG++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG
Sbjct: 304 ATTRDWDVNEGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFG 363
Query: 436 MVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNK 494
+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN
Sbjct: 364 LTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNN 423
Query: 495 GTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKS 554
+VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKS
Sbjct: 424 QSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKS 483
Query: 555 GTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVL 614
GTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+P+ ++ P+L
Sbjct: 484 GTAQIADEKNGGYLVGSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPIL 543
Query: 615 EEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNK 672
E A +M +L+ + T E+SY I +PGE A LR+N+V PIV+G G K
Sbjct: 544 ERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTK 603
Query: 673 IEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTV 732
I++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V
Sbjct: 604 IKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VV 662
Query: 733 TKQSVAAGEALSKTKKITITLGD 755
KQ V A+ KKI +TLGD
Sbjct: 663 QKQDVRTNTAIKNIKKIKLTLGD 685
>gi|148714912|gb|ABR03882.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 684
Score = 652 bits (1681), Expect = 0.0, Method: Composition-based stats.
Identities = 345/687 (50%), Positives = 489/687 (71%), Gaps = 7/687 (1%)
Query: 54 TDSKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTR 113
T ++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T
Sbjct: 1 TGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATG 60
Query: 114 EKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKT 173
+ LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K
Sbjct: 61 KILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKE 120
Query: 174 FKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLT 233
+ A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L
Sbjct: 121 LEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILA 179
Query: 234 GTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGIN 293
GTDG YEKD+ GN + GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG
Sbjct: 180 GTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKY 239
Query: 294 ASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAA 353
+AT+V+AKTGEILATTQRPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AA
Sbjct: 240 MTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAA 298
Query: 354 INNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQA 413
I+N +F P N++ +K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ
Sbjct: 299 IDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQK 357
Query: 414 MGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFT 472
MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFT
Sbjct: 358 MGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFT 417
Query: 473 AISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGT 532
AI+N+G+MLEP+FI + D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT
Sbjct: 418 AIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGT 477
Query: 533 LYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMY 592
+YN S G P + V +VA+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+Y
Sbjct: 478 MYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILY 537
Query: 593 VTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTP 650
VTVQ+P+ ++ NP+LE A +M +L+ T+ ++++ Y + +P
Sbjct: 538 VTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISP 597
Query: 651 GETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKN 710
G+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK+
Sbjct: 598 GDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKET 657
Query: 711 VETFAKWKGIKITYKGGKSGTVTKQSV 737
ET AKW I++ ++G S TV KQ V
Sbjct: 658 AETLAKWLNIELEFQGSGS-TVQKQDV 683
>gi|148714956|gb|ABR03904.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 683
Score = 651 bits (1680), Expect = 0.0, Method: Composition-based stats.
Identities = 346/685 (50%), Positives = 488/685 (71%), Gaps = 7/685 (1%)
Query: 56 SKFGVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREK 115
++FG DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T +
Sbjct: 2 TRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKI 61
Query: 116 LYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFK 175
LYV+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K +
Sbjct: 62 LYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELE 121
Query: 176 DAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGT 235
A +KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GT
Sbjct: 122 TAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGT 180
Query: 236 DGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINAS 295
DG YEKD+ GN + GTE I+++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +
Sbjct: 181 DGIITYEKDRLGNIVPGTEQISQQTVDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMT 240
Query: 296 ATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAIN 355
AT+V+AKTGEILATTQRPT+N+DT EG K + W + LY++ YEPGS MKVM L+A+I+
Sbjct: 241 ATLVSAKTGEILATTQRPTFNADTKEG-ITKDFVWRDILYQSNYEPGSAMKVMTLAASID 299
Query: 356 NGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMG 415
N +F P Y N++ +K+ DV I DW +NEG++ G M+F+QGF++SSNVGMT+LEQ MG
Sbjct: 300 NNTF-PGGEYFNSSELKIADVTIRDWDVNEGLTGGGMMTFSQGFAHSSNVGMTLLEQKMG 358
Query: 416 DKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAI 474
D W +YL+ +KFG+PTRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI
Sbjct: 359 DATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAI 418
Query: 475 SNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLY 534
+N+G+MLEP+FI + D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+Y
Sbjct: 419 ANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMY 478
Query: 535 NKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVT 594
N S G P + V +VA+KSGTAQ+ DEK G Y VG + S V+M P+E+P++I+YVT
Sbjct: 479 NHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTNYIFSAVSMSPAENPDFILYVT 538
Query: 595 VQEPKTWNNNFFATVVNPVLEEAMSMGATLDTSVSEGSGK--TEETSYQTGDIIGKTPGE 652
VQ+P+ ++ NP+LE A +M +L+ + S + ++++ Y + +PG+
Sbjct: 539 VQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKSLEQVSQQSPYPMPSVKDISPGD 598
Query: 653 TANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVE 712
A LR+NLV PIV+G G KI+ S + +N+ N+Q+LI++++ E+PDMYGWTK E
Sbjct: 599 LAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKATAE 658
Query: 713 TFAKWKGIKITYKGGKSGTVTKQSV 737
TFAKW I++ ++G + TV KQ V
Sbjct: 659 TFAKWLNIELEFEGSGT-TVQKQDV 682
>gi|149001554|ref|ZP_01826527.1| Penicillin-binding protein 2X [Streptococcus pneumoniae SP14-BS69]
gi|147760012|gb|EDK67001.1| Penicillin-binding protein 2X [Streptococcus pneumoniae SP14-BS69]
Length = 690
Score = 650 bits (1678), Expect = 0.0, Method: Composition-based stats.
Identities = 338/671 (50%), Positives = 482/671 (71%), Gaps = 6/671 (0%)
Query: 12 LNYVVRDRRKPAQNRQHVGQNLMVLSIFIFFVFIINFVVIIGTDSKFGVDLSTQAAKSYN 71
+ Y ++R+ PA+NR+ VG++L +LS+F+F +F++NF VIIGT ++FG DL+ +A K +
Sbjct: 8 IRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQ 67
Query: 72 TKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILK 131
T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++
Sbjct: 68 TTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFH 127
Query: 132 DKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRM 191
L +++SY QL QVSFG KG GITY+ ++K + A +KG+ F + +R
Sbjct: 128 KYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRS 187
Query: 192 YPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLL 251
YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN +
Sbjct: 188 YPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVP 246
Query: 252 GTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQ 311
GTE +++ +DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQ
Sbjct: 247 GTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQ 306
Query: 312 RPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGI 371
RPT+++DT EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +
Sbjct: 307 RPTFDADTKEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSEL 364
Query: 372 KVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIP 431
K+ D I DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+P
Sbjct: 365 KIADATIRDWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVP 424
Query: 432 TRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVA 490
TRFG+ E +G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI +
Sbjct: 425 TRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIY 484
Query: 491 DTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDV 550
D N T R ++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +V
Sbjct: 485 DPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNV 544
Query: 551 AVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVV 610
A+KSGTAQ+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++
Sbjct: 545 ALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFA 604
Query: 611 NPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLG 668
NP+LE A +M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G
Sbjct: 605 NPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVG 664
Query: 669 VGNKIEKVSVD 679
G KI+ S +
Sbjct: 665 TGTKIKNSSAE 675
>gi|1942406|pdb|1PMD| Chain , Penicillin-Binding Protein 2x (Pbp-2x)
Length = 675
Score = 650 bits (1676), Expect = 0.0, Method: Composition-based stats.
Identities = 344/679 (50%), Positives = 485/679 (71%), Gaps = 7/679 (1%)
Query: 80 RGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKS 139
RGTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++S
Sbjct: 1 RGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEES 60
Query: 140 YTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFAS 199
Y QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS
Sbjct: 61 YVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFAS 120
Query: 200 EFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKE 259
F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++
Sbjct: 121 SFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQR 179
Query: 260 AIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDT 319
+DGK++YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT
Sbjct: 180 TMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADT 239
Query: 320 LEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEIN 379
EG + + W + LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I
Sbjct: 240 KEG-ITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIR 297
Query: 380 DWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGE 439
DW +NEG++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E
Sbjct: 298 DWDVNEGLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDE 357
Query: 440 SSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVR 498
+G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R
Sbjct: 358 YAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTAR 417
Query: 499 TAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQ 558
++KE++G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ
Sbjct: 418 KSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQ 477
Query: 559 VPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAM 618
+ DEK G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A
Sbjct: 478 IADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERAS 537
Query: 619 SMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKV 676
+M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+
Sbjct: 538 AMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNS 597
Query: 677 SVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQS 736
S + +N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ
Sbjct: 598 SAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQD 656
Query: 737 VAAGEALSKTKKITITLGD 755
V A A+ KKIT+TLGD
Sbjct: 657 VRANTAIKDIKKITLTLGD 675
>gi|148715062|gb|ABR03957.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 679
Score = 645 bits (1665), Expect = 0.0, Method: Composition-based stats.
Identities = 345/682 (50%), Positives = 483/682 (70%), Gaps = 7/682 (1%)
Query: 59 GVDLSTQAAKSYNTKTIVAAKRGTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYV 118
G DL+ +A K + T V AKRGTIYDRNG +AED+TSY++YA++ +Y S T + LYV
Sbjct: 1 GTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYV 60
Query: 119 QESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAG 178
+++QF+KVA++ L +++SY QL QVSFG KG GITY+ ++K + A
Sbjct: 61 EKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMTIKKELETAE 120
Query: 179 IKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGE 238
+KG+ F + +R YPNG FAS F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG
Sbjct: 121 VKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGI 179
Query: 239 AIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATV 298
YEKD+ GN + GTE ++++ +DGK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+
Sbjct: 180 ITYEKDRLGNIVPGTELVSQQTVDGKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATL 239
Query: 299 VNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGS 358
V+AKTGEILATTQRPT+N+DT EG + + W + LY++ YEPGS MKVM L+++I+N +
Sbjct: 240 VSAKTGEILATTQRPTFNADTKEG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNT 298
Query: 359 FNPNATYSNANGIKVGDVEINDWSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKV 418
F P+ Y N++ K+ D DW +N G++ G M+F QGF++SSNVGM++LEQ MGD
Sbjct: 299 F-PSGEYFNSSEFKIADATTRDWDVNAGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDAT 357
Query: 419 WSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNN 477
W +YL +KFG+PTRFG+ E +G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+
Sbjct: 358 WLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIAND 417
Query: 478 GIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKS 537
G+MLEP+FI + DTN +VR ++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN
Sbjct: 418 GVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHY 477
Query: 538 EGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQE 597
G PII V +VAVKSGTAQ+ DEK G Y VG+ + S V M P+E+P++I+YVTVQ+
Sbjct: 478 TGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGSTNYIFSGVTMNPAENPDFILYVTVQQ 537
Query: 598 PKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETAN 655
P+ ++ P+LE A +M +L+ + T E+SY I +PGE A
Sbjct: 538 PEHYSGIQLGEFATPILERASAMKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAE 597
Query: 656 TLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFA 715
LR+N+V PIV+G G KI++ SV+ N+ N+Q+L+++++ E+PDMYGW K+ ETFA
Sbjct: 598 ALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFA 657
Query: 716 KWKGIKITYKGGKSGTVTKQSV 737
KW I++ ++G S V KQ V
Sbjct: 658 KWLDIELEFEGSGS-VVQKQDV 678
>gi|154794062|gb|ABS86079.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 672
Score = 642 bits (1655), Expect = 0.0, Method: Composition-based stats.
Identities = 342/676 (50%), Positives = 480/676 (71%), Gaps = 7/676 (1%)
Query: 83 IYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTL 142
IYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 1 IYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVR 60
Query: 143 AQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFL 202
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+
Sbjct: 61 EQLSQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFI 120
Query: 203 GRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAID 262
G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +D
Sbjct: 121 GLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVD 179
Query: 263 GKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEG 322
GK++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 GKDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG 239
Query: 323 QAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWS 382
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW
Sbjct: 240 -ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWD 297
Query: 383 INEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG 442
+N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G
Sbjct: 298 VNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAG 357
Query: 443 -IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAK 501
+ + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++
Sbjct: 358 QLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQ 417
Query: 502 KEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPD 561
KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ D
Sbjct: 418 KEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIAD 477
Query: 562 EKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMG 621
EK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M
Sbjct: 478 EKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMK 537
Query: 622 ATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVD 679
+L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 538 ESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVE 597
Query: 680 AKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAA 739
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 598 EGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRT 656
Query: 740 GEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 657 NTAIKNIKKIKLTLGD 672
>gi|1781320|emb|CAA55062.1| penicilin-binding protein [Streptococcus oralis]
Length = 666
Score = 641 bits (1654), Expect = 0.0, Method: Composition-based stats.
Identities = 340/668 (50%), Positives = 479/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 3 IAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQLAQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 TQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGLESSLNTILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGSTMKVM L+++I+N +F P+ Y N++ +K+ D I DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSTMKVMTLASSIDNNTF-PSGEYFNSSELKIADATIRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
R M+F+QGF++SSNVGM++LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 RMMTFSQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++GKPV
Sbjct: 360 NIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGKPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
S+ AAS TR MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SEDAASLTRTNMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSAAQLGEFSNPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV+ +N+ N
Sbjct: 540 AKNLDQVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKETSVEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|66817098|gb|AAY56848.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 671
Score = 640 bits (1650), Expect = 0.0, Method: Composition-based stats.
Identities = 341/675 (50%), Positives = 480/675 (71%), Gaps = 7/675 (1%)
Query: 84 YDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLA 143
YDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 1 YDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVRE 60
Query: 144 QLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLG 203
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 61 QLSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIG 120
Query: 204 RAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDG 263
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DG
Sbjct: 121 LAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDG 179
Query: 264 KNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQ 323
K++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT +G
Sbjct: 180 KDVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKDG- 238
Query: 324 AKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSI 383
K + W + LY+ YEPGS MKVM L+++I+N +F P Y N++ K+ DV DW +
Sbjct: 239 ITKDFVWRDILYQGNYEPGSAMKVMTLASSIDNNTF-PGGEYFNSSESKIADVTTRDWDV 297
Query: 384 NEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG- 442
NEG++ G M+F+QGF++SSNVGM +LE+ MGD W +YL+ +KFG+PTRFG+ E +G
Sbjct: 298 NEGLTGGGMMTFSQGFAHSSNVGMILLEEKMGDTTWLDYLNRFKFGVPTRFGLTDEYAGQ 357
Query: 443 IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKK 502
+ + N V+IAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++K
Sbjct: 358 LPADNIVSIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNDQTVRKSQK 417
Query: 503 EVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDE 562
E++G PVSK AAS+TR M+ VGTDP +GT+YN S G PI+ V +VA+KSGTAQ+ DE
Sbjct: 418 EIVGNPVSKDAASQTRTQMVLVGTDPVYGTMYNHSTGKPIVTVPGQNVALKSGTAQIADE 477
Query: 563 KTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGA 622
K G Y VG + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 478 KNGGYLVGPTNYIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKE 537
Query: 623 TLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDA 680
+L+ + T E+SY I +PGE A TLR+N+V PIV+G G KI++ SV+
Sbjct: 538 SLNLQSPAKNLDQVTTESSYAMPSIKDISPGELAETLRRNIVQPIVVGTGTKIKETSVEE 597
Query: 681 KENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAG 740
+N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 598 GKNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRTN 656
Query: 741 EALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 657 TAIKNIKKIKLTLGD 671
>gi|66817084|gb|AAY56841.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 674
Score = 638 bits (1646), Expect = 0.0, Method: Composition-based stats.
Identities = 342/678 (50%), Positives = 479/678 (70%), Gaps = 7/678 (1%)
Query: 81 GTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSY 140
GTIYDRNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y
Sbjct: 1 GTIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAY 60
Query: 141 TLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASE 200
QL QVSFG KG GITY+ ++K KDA I+G+ F + +R YPNG FAS
Sbjct: 61 VKEQLSQPNLTQVSFGAKGNGITYANMMAIKKDLKDASIEGIDFTTSPNRSYPNGQFASS 120
Query: 201 FLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEA 260
F+G A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++
Sbjct: 121 FIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQT 179
Query: 261 IDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTL 320
+DGK++YTT+S+ LQ+F+ETQM+ F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT
Sbjct: 180 VDGKDVYTTISSTLQSFMETQMNAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTK 239
Query: 321 EGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEIND 380
EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D D
Sbjct: 240 EG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRD 297
Query: 381 WSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGES 440
W +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E
Sbjct: 298 WDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEY 357
Query: 441 SG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRT 499
+G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR
Sbjct: 358 AGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRK 417
Query: 500 AKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQV 559
++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+
Sbjct: 418 SQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQI 477
Query: 560 PDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMS 619
DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +
Sbjct: 478 ADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASA 537
Query: 620 MGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVS 677
M +L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ S
Sbjct: 538 MKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETS 597
Query: 678 VDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
V+ N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S V KQ V
Sbjct: 598 VEEGTNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFEGSGS-VVQKQDV 656
Query: 738 AAGEALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 657 RTNTAIKNIKKIKLTLGD 674
>gi|66817080|gb|AAY56839.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 670
Score = 638 bits (1645), Expect = 0.0, Method: Composition-based stats.
Identities = 340/674 (50%), Positives = 478/674 (70%), Gaps = 7/674 (1%)
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY Q
Sbjct: 1 DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQ 60
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 61 LSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGL 120
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK
Sbjct: 121 AQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGK 179
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTT+S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 DVYTTISSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-I 238
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 239 TEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVN 297
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 298 DGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQL 357
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE
Sbjct: 358 PADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKE 417
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 418 IVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEK 477
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +
Sbjct: 478 NGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKES 537
Query: 624 LD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 538 LNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEG 597
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 598 TNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNT 656
Query: 742 ALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 657 AIKNIKKITLTLGD 670
>gi|6689319|emb|CAB65444.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 637 bits (1644), Expect = 0.0, Method: Composition-based stats.
Identities = 339/668 (50%), Positives = 477/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+AAI+N +F P Y N++ +K+ DV I DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMTLAAAIDNNTF-PGGEYFNSSELKIADVTIRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
R M+F QGF+ SSNVGM++LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 RMMTFLQGFALSSNVGMSLLEQKMGDPTWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PV
Sbjct: 360 NIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNDQTVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS TR MI VGTDP +GT+YN S G P + V +VA+KSGTA++ DEK G Y V
Sbjct: 420 SKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAEIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A TLR+N+V PIV+G G KI++ SV+ +N+ N
Sbjct: 540 AKNLDQVTTESSYAMPSIKDISPGELAETLRRNIVQPIVVGTGTKIKETSVEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|10178942|emb|CAC08465.1| penicillin binding protein 2x [Streptococcus mitis]
Length = 671
Score = 637 bits (1642), Expect = e-180, Method: Composition-based stats.
Identities = 339/675 (50%), Positives = 479/675 (70%), Gaps = 7/675 (1%)
Query: 82 TIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYT 141
TIYDRNG +AED+TSY++YA++ Y S T + LYV+ SQF+KVA++ L + ++Y
Sbjct: 1 TIYDRNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEGSQFNKVAEVFHKYLDMDEAYV 60
Query: 142 LAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEF 201
QL QVSFG KG GITY+ ++K K+A ++G+ F + +R YPNG FAS F
Sbjct: 61 KEQLAQPNLTQVSFGAKGNGITYASMMAIKKELKEASVEGIDFTTSPNRSYPNGQFASSF 120
Query: 202 LGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAI 261
+G A+ EN+ DGS SL+G +GLE SLN++L GTDG YEKD+ GN + GTE I+++ +
Sbjct: 121 IGLAQLHENE-DGSKSLLGTSGLESSLNTILAGTDGIITYEKDRLGNIVPGTEQISQKTV 179
Query: 262 DGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLE 321
+GK++YTTLS+PLQ+F+ETQM+ F+E+ KG +AT+V+AKTGEILATTQRPT+++DT E
Sbjct: 180 NGKDVYTTLSSPLQSFMETQMNAFLEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKE 239
Query: 322 GQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDW 381
G K + W + LY++ YEPGSTMKVM L+A+I+N +F P + N++ +K+ D I DW
Sbjct: 240 G-ITKDFVWRDILYQSNYEPGSTMKVMTLAASIDNNTF-PGGEFFNSSELKIADATIRDW 297
Query: 382 SINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESS 441
+NEG++ G M+F+QGF++SSN+GMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +
Sbjct: 298 DVNEGLTGGGMMTFSQGFAHSSNIGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYA 357
Query: 442 G-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTA 500
G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N +VR +
Sbjct: 358 GQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNNQSVRKS 417
Query: 501 KKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVP 560
+KE++G PVSK AAS+TR +M+ VGTDP +GT+YN S G + V +VA+KSGTAQ+
Sbjct: 418 QKEIVGNPVSKDAASQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAQIA 477
Query: 561 DEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSM 620
DEK G Y VG+ + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M
Sbjct: 478 DEKNGGYLVGSTNYIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAM 537
Query: 621 GATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSV 678
+L+ + T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV
Sbjct: 538 KDSLNLLSPAKNLDQVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSV 597
Query: 679 DAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVA 738
+ N+ N+Q+L+++++ E+PDMYGW K ETFAKW IK+ ++G S V KQ V
Sbjct: 598 EEGTNLAPNQQVLLLSDKVEEIPDMYGWKKGTAETFAKWLDIKLEFEGSGS-VVQKQDVR 656
Query: 739 AGEALSKTKKITITL 753
A+ KKI +TL
Sbjct: 657 TNTAIKNIKKIKLTL 671
>gi|66817110|gb|AAY56854.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 666
Score = 636 bits (1641), Expect = e-180, Method: Composition-based stats.
Identities = 341/668 (51%), Positives = 478/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTFGLESSLNTILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT +G K + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKDG-ITKDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY+ YEPGS MKVM L+++I+N +F P Y N++ K+ DV DW +NEG++ G
Sbjct: 241 RDILYQGNYEPGSAMKVMTLASSIDNNTF-PGGEYFNSSESKIADVTTRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVGM +LE+ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGMILLEEKMGDTTWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNDQTVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS+TR M+ VGTDP +GT+YN S G PI+ V +VA+KSGTAQ+ DEK G Y V
Sbjct: 420 SKDAASQTRTQMVLVGTDPVYGTMYNHSTGKPIVTVPGQNVALKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GPTNYIFSVVAMNPAENPDFILYVTVQQPEHFSGIQLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A TLR+N+V PIV+G G KI++ SV+ +N+ N
Sbjct: 540 AKNLDQVTTESSYAMPSIKDISPGELAETLRRNIVQPIVVGTGTKIKETSVEEGKNLSPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK+ ETFAKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFEGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|517186|emb|CAA55061.1| penicilin-binding protein [Streptococcus mitis]
Length = 666
Score = 635 bits (1639), Expect = e-180, Method: Composition-based stats.
Identities = 335/668 (50%), Positives = 476/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 3 IAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQLAQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 TQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGLESSLNTILAGTDGIITYEKDRVGNIVPGTEQVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGSTMKVM L+++I+N +F P Y N++ +K+ D I DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSTMKVMTLASSIDNNTF-PGGEYFNSSELKIADATIRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSN+GMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNIGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PV
Sbjct: 360 NIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNDQTVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS+TR +M+ VGTDP +GT+YN S G + V +VA+KSGTAQ+ DEK G Y V
Sbjct: 420 SKDAASQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDQVTTESSYAMPSIKDISPGDLAERLRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIQLTLGD 666
>gi|66817100|gb|AAY56849.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 669
Score = 635 bits (1638), Expect = e-180, Method: Composition-based stats.
Identities = 339/673 (50%), Positives = 477/673 (70%), Gaps = 7/673 (1%)
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 1 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 60
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 61 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 120
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 121 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKD 179
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 238
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+
Sbjct: 239 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVND 297
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 298 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 357
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 358 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 417
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 418 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 477
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 478 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 537
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 538 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 597
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 598 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 656
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 657 IKNIKKIKLTLGD 669
>gi|66817106|gb|AAY56852.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 670
Score = 635 bits (1637), Expect = e-180, Method: Composition-based stats.
Identities = 338/674 (50%), Positives = 477/674 (70%), Gaps = 7/674 (1%)
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY Q
Sbjct: 1 DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQ 60
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 61 LSQPNLKQVSFGAKGNGITYANMMTIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGL 120
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK
Sbjct: 121 AQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTELVSQQTVDGK 179
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 DVYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-I 238
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 239 TEDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVN 297
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
EG++ G M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 298 EGLTTGGMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQL 357
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE
Sbjct: 358 PADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKE 417
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSG AQ+ DEK
Sbjct: 418 IVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGAAQIADEK 477
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +
Sbjct: 478 NGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKES 537
Query: 624 LD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 538 LNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEG 597
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 598 TNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNT 656
Query: 742 ALSKTKKITITLGD 755
A+ KKI +TLGD
Sbjct: 657 AIKNIKKIKLTLGD 670
>gi|66817086|gb|AAY56842.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 669
Score = 634 bits (1636), Expect = e-180, Method: Composition-based stats.
Identities = 338/673 (50%), Positives = 477/673 (70%), Gaps = 7/673 (1%)
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 1 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 60
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 61 SQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 120
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 121 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 179
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 VYTTISSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 238
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+
Sbjct: 239 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVND 297
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 298 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 357
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 358 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 417
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 418 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 477
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 478 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 537
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 538 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 597
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 598 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 656
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 657 IKNIKKIKLTLGD 669
>gi|66817102|gb|AAY56850.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 670
Score = 634 bits (1635), Expect = e-180, Method: Composition-based stats.
Identities = 338/674 (50%), Positives = 480/674 (71%), Gaps = 7/674 (1%)
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY Q
Sbjct: 1 DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQ 60
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 61 LSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGL 120
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK
Sbjct: 121 AQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGK 179
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 DVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-I 238
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 239 TEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVN 297
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 298 DGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQL 357
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE
Sbjct: 358 PADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKE 417
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 418 IVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEK 477
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +
Sbjct: 478 NGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKDS 537
Query: 624 LD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S +
Sbjct: 538 LNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEG 597
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
+N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A
Sbjct: 598 KNLAPNQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANT 656
Query: 742 ALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 657 AIKDIKKITLTLGD 670
>gi|66817094|gb|AAY56846.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 670
Score = 634 bits (1634), Expect = e-180, Method: Composition-based stats.
Identities = 341/674 (50%), Positives = 483/674 (71%), Gaps = 7/674 (1%)
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY Q
Sbjct: 1 DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQ 60
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 61 LSQPNLKQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGL 120
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK
Sbjct: 121 AQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGK 179
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 180 DVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLT 239
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
K + W + LY++ YEPGSTMKVM L+AAI+N +F P N++ +KV DV I DW +N
Sbjct: 240 KD-FVWRDILYQSNYEPGSTMKVMTLAAAIDNNTF-PGGEVFNSSELKVADVTIRDWDVN 297
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
EG++ G M+F+QGF+ SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 298 EGLTGGGMMTFSQGFALSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQL 357
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N +VR ++KE
Sbjct: 358 PADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKE 417
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK+AAS TR++M+ VGTDP +GT+YN S G P + V +VA+KSGTA++ DEK
Sbjct: 418 IVGNPVSKEAASVTRDHMVMVGTDPTYGTMYNHSTGKPTVTVPGQNVALKSGTAEIADEK 477
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VGT + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +
Sbjct: 478 NGGYLVGTTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKES 537
Query: 624 LDTSVSEGSGK--TEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ + + + ++ TSY TPG+ A LR+NLV PIV+G G KI++ SV+
Sbjct: 538 LNLQSTAKNLEQFSKTTSYAMPATKDYTPGDLAEELRRNLVQPIVVGTGTKIKETSVEEG 597
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S TV KQ V A
Sbjct: 598 TNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLNIELEFEGSGS-TVQKQDVRANT 656
Query: 742 ALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 657 AIKDIKKITLTLGD 670
>gi|66817112|gb|AAY56855.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 669
Score = 633 bits (1633), Expect = e-179, Method: Composition-based stats.
Identities = 337/673 (50%), Positives = 474/673 (70%), Gaps = 7/673 (1%)
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y QL
Sbjct: 1 RNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVKEQL 60
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+G A
Sbjct: 61 SQPNLTQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFIGLA 120
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 121 QLHENE-DGSKSLLGTSGLESSLNTILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 179
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 238
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 239 EDFVWRDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNA 297
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 298 GLTTGGMMTFLQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 357
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 358 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 417
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 418 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 477
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 478 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHFSGIQLGEFATPILERASAMKESL 537
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 538 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 597
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 598 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 656
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 657 IKNIKKIKLTLGD 669
>gi|66817078|gb|AAY56838.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 670
Score = 633 bits (1633), Expect = e-179, Method: Composition-based stats.
Identities = 339/674 (50%), Positives = 477/674 (70%), Gaps = 7/674 (1%)
Query: 85 DRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQ 144
DRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY Q
Sbjct: 1 DRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQ 60
Query: 145 LRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGR 204
L QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G
Sbjct: 61 LSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGL 120
Query: 205 AEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGK 264
A+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK
Sbjct: 121 AQLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGK 179
Query: 265 NIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQA 324
++YTT+S+ LQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 DVYTTISSTLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-I 238
Query: 325 KKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSIN 384
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N
Sbjct: 239 TEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVN 297
Query: 385 EGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-I 443
+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 298 DGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQL 357
Query: 444 VSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKE 503
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE
Sbjct: 358 PADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKE 417
Query: 504 VIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEK 563
++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 418 IVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEK 477
Query: 564 TGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT 623
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +
Sbjct: 478 NGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKES 537
Query: 624 LD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAK 681
L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 538 LNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEG 597
Query: 682 ENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGE 741
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 598 TNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRANT 656
Query: 742 ALSKTKKITITLGD 755
A+ KKIT+TLGD
Sbjct: 657 AIKDIKKITLTLGD 670
>gi|6689325|emb|CAB65447.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 633 bits (1632), Expect = e-179, Method: Composition-based stats.
Identities = 333/668 (49%), Positives = 480/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
R M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 RMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIA S+FGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + D N +VR ++KE++G PV
Sbjct: 360 NIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TR++M+ VGTDP +GT+YN S G + V +VA+KSGTA++ DEK G Y
Sbjct: 420 SKEAASVTRDHMVMVGTDPTYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLT 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ T+
Sbjct: 480 GSTNNIFSVVSMHPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQTT 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +N+ N
Sbjct: 540 AKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK+ ETFAKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFEGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|47330|emb|CAA46265.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 633 bits (1632), Expect = e-179, Method: Composition-based stats.
Identities = 335/668 (50%), Positives = 476/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
R M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 RMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE++G PV
Sbjct: 360 NIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK G Y V
Sbjct: 420 SKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ T+
Sbjct: 480 GLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTT 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +N+ N
Sbjct: 540 AKALEQVSKQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|1553053|emb|CAA67013.1| penicillin-binding protein [Streptococcus pneumoniae]
Length = 666
Score = 633 bits (1632), Expect = e-179, Method: Composition-based stats.
Identities = 336/668 (50%), Positives = 476/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLAMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT +G K + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKDG-ITKDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY+ YEPGS MKVM+L+++I+N +F P Y N++ K+ DV DW +NEG++ G
Sbjct: 241 RDILYQGNYEPGSAMKVMMLASSIDNNTF-PGGEYFNSSESKIADVTTRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVGM +LE+ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGMILLEEKMGDTTWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNDQTVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS+TR M+ VGTDP +GT+YN S G PI+ V +VA+KSGTAQ+ DEK G Y V
Sbjct: 420 SKDAASQTRTQMVLVGTDPVYGTMYNHSTGKPIVTVPGQNVALKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GPTNYIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A TLR+N+V PIV+G G KI++ SV+ +N+ N
Sbjct: 540 AKNLDQVTTESSYAMPSIKDISPGELAETLRRNIVQPIVVGTGTKIKETSVEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|66817114|gb|AAY56856.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 669
Score = 632 bits (1631), Expect = e-179, Method: Composition-based stats.
Identities = 337/673 (50%), Positives = 474/673 (70%), Gaps = 7/673 (1%)
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y QL
Sbjct: 1 RNGVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVKEQL 60
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 61 SQPNLTQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 120
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 121 QLHENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 179
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 VYTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 238
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+
Sbjct: 239 EDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVND 297
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G +
Sbjct: 298 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLP 357
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 358 ADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 417
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 418 VGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 477
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 478 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 537
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+
Sbjct: 538 NLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGT 597
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 598 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 656
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 657 IKNIKKIKLTLGD 669
>gi|23451806|gb|AAN32865.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 661
Score = 632 bits (1631), Expect = e-179, Method: Composition-based stats.
Identities = 340/665 (51%), Positives = 472/665 (70%), Gaps = 7/665 (1%)
Query: 94 DSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQV 153
D+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL QV
Sbjct: 1 DATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQV 60
Query: 154 SFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKD 213
SFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN+ D
Sbjct: 61 SFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-D 119
Query: 214 GSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAP 273
GS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK++YTT+S+P
Sbjct: 120 GSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSP 179
Query: 274 LQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR 333
LQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K + W +
Sbjct: 180 LQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITKDFVWRDI 238
Query: 334 LYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTM 393
LY++ YEPGSTMKVM+L+AAI+N +F P N++ +K+ D I DW +NEG++ G M
Sbjct: 239 LYQSNYEPGSTMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGGGMM 297
Query: 394 SFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIA 452
+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIA
Sbjct: 298 TFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIA 357
Query: 453 QSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQ 512
QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KEV+G PVSK
Sbjct: 358 QSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEVVGNPVSKD 417
Query: 513 AASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTN 572
AAS TR MI VGTDP +GT+YN S G P + V +VA+KSGTA++ DEK G Y VG+
Sbjct: 418 AASLTRTNMILVGTDPVYGTMYNHSTGKPTVNVPGQNVALKSGTAEIADEKNGGYLVGST 477
Query: 573 ETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSE 630
+ SVVAM P+EDP++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 478 NNIFSVVAMNPAEDPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQSPAKN 537
Query: 631 GSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQI 690
T E+SY I +PG+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+
Sbjct: 538 LDKVTTESSYAMPSIKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQV 597
Query: 691 LIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKIT 750
LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A+ KKIT
Sbjct: 598 LILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTAIKDIKKIT 656
Query: 751 ITLGD 755
+TLGD
Sbjct: 657 LTLGD 661
>gi|66817104|gb|AAY56851.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 668
Score = 632 bits (1631), Expect = e-179, Method: Composition-based stats.
Identities = 338/672 (50%), Positives = 476/672 (70%), Gaps = 7/672 (1%)
Query: 87 NGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLR 146
NG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 1 NGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLS 60
Query: 147 TKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAE 206
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+
Sbjct: 61 QPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQ 120
Query: 207 PIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNI 266
EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++
Sbjct: 121 LHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDV 179
Query: 267 YTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKK 326
YTTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG +
Sbjct: 180 YTTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITE 238
Query: 327 GYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEG 386
+ W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+G
Sbjct: 239 DFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDG 297
Query: 387 ISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVS 445
++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + +
Sbjct: 298 LTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPA 357
Query: 446 QNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVI 505
N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++
Sbjct: 358 DNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIV 417
Query: 506 GKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTG 565
G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G
Sbjct: 418 GNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNG 477
Query: 566 TYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD 625
Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+
Sbjct: 478 GYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLN 537
Query: 626 --TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKEN 683
+ T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N
Sbjct: 538 LQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTN 597
Query: 684 IKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEAL 743
+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+
Sbjct: 598 LAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAI 656
Query: 744 SKTKKITITLGD 755
KKI +TLGD
Sbjct: 657 KNIKKIKLTLGD 668
>gi|2253201|emb|CAA71561.1| pbp2x [Streptococcus mitis]
Length = 666
Score = 632 bits (1630), Expect = e-179, Method: Composition-based stats.
Identities = 339/668 (50%), Positives = 472/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ Y S + LYV+ESQ++KVA+I L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDKDYKSANGDILYVEESQYNKVAEIFHKYLDMEESYVKEQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A ++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGTKGNGITYANMMSIKKDLEAAKVEGVNFTTSPNRSYPNGKFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SLIG +G+E SLNSLL GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLIGTSGIESSLNSLLAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSGMKVMTLASSIDNNTF-PSGEYFNSSEFKMADATTRDWDVNEGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 SMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|66817096|gb|AAY56847.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 669
Score = 632 bits (1630), Expect = e-179, Method: Composition-based stats.
Identities = 337/673 (50%), Positives = 478/673 (71%), Gaps = 7/673 (1%)
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 1 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 60
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 61 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 120
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 121 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 179
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 180 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 238
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 239 EDFVWRDILYQSNYEPGSTMKVMTLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 297
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 298 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 357
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIA S+FGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + D N +VR ++KEV
Sbjct: 358 ADNIVNIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALYDPNDQSVRKSQKEV 417
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK+AAS TR+ M+ VGTDP +GT+YN S G + V +VA+KSGTA++ DEK
Sbjct: 418 VGNPVSKEAASVTRDQMVMVGTDPTYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKN 477
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 478 GGYLVGSTNNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 537
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ + T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV+ +
Sbjct: 538 NLQSPAKNLDQVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVEEGK 597
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A
Sbjct: 598 NLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTA 656
Query: 743 LSKTKKITITLGD 755
+ KKI +TLGD
Sbjct: 657 IKNIKKIKLTLGD 669
>gi|1553055|emb|CAA67010.1| penicillin-binding protein [Streptococcus pneumoniae]
Length = 666
Score = 631 bits (1628), Expect = e-179, Method: Composition-based stats.
Identities = 340/668 (50%), Positives = 473/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 3 IAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQLAQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 TQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G GLE SLN++L GTDG YEKD GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTFGLESSLNTILAGTDGIITYEKDGVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY+ YEPGS MKVM L+++I+N +F P Y N++ K+ DV DW +NEG++ G
Sbjct: 241 RDILYQGNYEPGSAMKVMTLASSIDNNTF-PGGEYFNSSESKIADVTTRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVGM +LE+ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGMILLEEKMGDTTWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++GKPV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGKPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
S+ AAS TR MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SEDAASLTRTNMILVGTDPLYGTMYNHQTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHFSGIQLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
+ +TSY I +PG+ A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDQVSSQTSYAMPSIKNISPGDLAEELRRNIVQPIVVGTGTKIKESSVEEGRNLSPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK+ ETFAKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFEGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KI ITLGD
Sbjct: 659 KIYITLGD 666
>gi|559528|emb|CAA46266.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 631 bits (1627), Expect = e-179, Method: Composition-based stats.
Identities = 336/668 (50%), Positives = 474/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|1553049|emb|CAA67011.1| penicillin-binding protein [Streptococcus pneumoniae]
Length = 666
Score = 630 bits (1625), Expect = e-178, Method: Composition-based stats.
Identities = 336/668 (50%), Positives = 472/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 3 IAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQLAQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K KDA ++G+ F +R YPNG FAS F+G A+ EN
Sbjct: 63 TQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTGPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTFGLESSLNTILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+P+Q+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT +G K + W
Sbjct: 182 SSPVQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKDG-ITKDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY+ YEPGS MKVM L+++I+N +F P Y N++ K+ DV I DW +NEG++ G
Sbjct: 241 RDILYQGNYEPGSAMKVMTLASSIDNNTF-PGGEYFNSSESKIADVTIRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVG +LE+ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGTILLEEKMGDTTWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNDQTVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS+TR M+ VGTDP +GT+YN S G PI+ V +VA+KSGTAQ+ DEK G Y V
Sbjct: 420 SKDAASQTRTQMVLVGTDPVYGTMYNHSTGKPIVTVPGQNVALKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GPTNYIFSVVAMNPAENPDFILYVTVQQPEHFSGIQLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A TLR+N+V PIV+G G KI++ SV+ +N+ N
Sbjct: 540 AKNLDQVTTESSYAMPSIKDISPGELAETLRRNIVQPIVVGTGTKIKETSVEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-IVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|6689323|emb|CAB65446.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 630 bits (1625), Expect = e-178, Method: Composition-based stats.
Identities = 334/668 (50%), Positives = 476/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFREKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM+L+AAI+N +F P N++ +K+ DV I DW++NEG++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMMLAAAIDNNTF-PGGEVFNSSELKIADVTIRDWNVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
R M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+ TRFG+ E +G + + N V
Sbjct: 300 RMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVSTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PV
Sbjct: 360 NIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNNQTVRRSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AA +TR +M+ VGTDP +GT+YN S G + V +VA+KSGTA++ DEK G Y V
Sbjct: 420 SKDAAGQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GSTNNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|47336|emb|CAA46264.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 630 bits (1624), Expect = e-178, Method: Composition-based stats.
Identities = 333/668 (49%), Positives = 476/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM+L+AAI+N +F P N++ +K+ D I DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSPMKVMMLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
R M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 RMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIAQSSFGQGIS TQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE++G PV
Sbjct: 360 NIAQSSFGQGISATQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS+TR +M+ VGTDP +GT+YN S G P + V +VA+KSGTA++ DEK G Y V
Sbjct: 420 SKDAASQTRTHMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAEIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
GT + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GTTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIPLGEFTNPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV+ ++ N
Sbjct: 540 AKNLDQVTTESSYTMPSIKDISPGDLAEELRRNIVQPIVVGTGTKIKESSVEEGTSLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGWTK E F+KW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELEFEGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|2253209|emb|CAA71564.1| pbp2X [Streptococcus oralis]
Length = 666
Score = 629 bits (1623), Expect = e-178, Method: Composition-based stats.
Identities = 337/668 (50%), Positives = 471/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ Y S + LYV+ESQ++KVA+I L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDKDYKSANGDILYVEESQYNKVAEIFHKYLDMEESYVKEQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ +++ + A ++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKQDLEAAKVEGVNFTTSPNRSYPNGKFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SLIG +G+E SLNSLL GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLIGTSGIESSLNSLLAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSGMKVMTLASSIDNNTF-PSGEYFNSSEFKMADATTRDWDVNEGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 SMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+ +++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVFLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|6689321|emb|CAB65445.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 629 bits (1623), Expect = e-178, Method: Composition-based stats.
Identities = 335/667 (50%), Positives = 475/667 (71%), Gaps = 7/667 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+ +QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVERTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGSKGNGITYANMMAMKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT +G K + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKDG-ITKDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+A+I+N +F P Y N++ +K+ D I DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMTLAASIDNNTF-PGGEYFNSSELKIADATIRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVGM++LEQ MGD W +YL+ +KFG+PTRFG+ E SG + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGMSLLEQKMGDTTWLDYLNRFKFGVPTRFGLTDEYSGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIA S+FGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++GKPV
Sbjct: 360 NIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGKPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
S+ AAS TR MI VGTDP +GT+YN G PII V +VA+KSGTA++ DEK G Y V
Sbjct: 420 SEDAASLTRTNMILVGTDPLYGTMYNHYTGKPIITVPGQNVALKSGTAEIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + VV M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GSTNYIFPVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDQVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+++++++ E+PDMYGW K+ ETFAKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVILLSDKVEEIPDMYGWKKETAETFAKWLNIELEFEGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLG 754
KIT+TLG
Sbjct: 659 KITLTLG 665
>gi|2253203|emb|CAA71562.1| pbp2x [Streptococcus mitis]
Length = 666
Score = 629 bits (1623), Expect = e-178, Method: Composition-based stats.
Identities = 337/668 (50%), Positives = 472/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY+IYA++ +Y S T + LYV++SQF+KVA+I L +++SY QL
Sbjct: 3 IAEDATSYNIYAVIDKTYKSATGKILYVEDSQFNKVAEIFHKYLDMEESYVKEQLSQPDL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG +G GITY+ ++ K AG++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGARGNGITYANMMAIKNDLKTAGVEGVDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DG+ LIG +GLE SLN++L GTDG YEKD+ GN + GT+ +++ +DGK++YTTL
Sbjct: 123 E-DGTKRLIGTSGLESSLNNILAGTDGIITYEKDRLGNIVPGTDQASQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLEKEKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSGMKVMTLASSIDNNTF-PSGEYFNSSEFKMADATTRDWDVNEGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 SMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|23451791|gb|AAN32859.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 661
Score = 629 bits (1623), Expect = e-178, Method: Composition-based stats.
Identities = 333/665 (50%), Positives = 473/665 (71%), Gaps = 7/665 (1%)
Query: 94 DSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQV 153
D+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL QV
Sbjct: 1 DATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQV 60
Query: 154 SFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKD 213
SFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN+ D
Sbjct: 61 SFGSKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-D 119
Query: 214 GSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAP 273
GS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+S+P
Sbjct: 120 GSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSP 179
Query: 274 LQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR 333
LQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG + + W +
Sbjct: 180 LQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVWRDI 238
Query: 334 LYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTM 393
LY++ YEPGS MKVM+L+AAI+N +F P N++ +K+ DV I DW +NEG++ GR M
Sbjct: 239 LYQSNYEPGSAMKVMMLAAAIDNNTF-PGGEVFNSSELKIADVTIRDWDVNEGLTGGRMM 297
Query: 394 SFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIA 452
+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIA
Sbjct: 298 TFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIA 357
Query: 453 QSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQ 512
QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PVSK
Sbjct: 358 QSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNNQTVRRSQKEIVGNPVSKD 417
Query: 513 AASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTN 572
AA +TR +M+ VGTDP +GT+YN S G + V +VA+KSGTA++ DEK G Y VG+
Sbjct: 418 AAGQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLVGST 477
Query: 573 ETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSE 630
+ SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ +
Sbjct: 478 NNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKESLNLQSPAKN 537
Query: 631 GSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQI 690
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N+Q+
Sbjct: 538 LDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQV 597
Query: 691 LIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKIT 750
L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ KKI
Sbjct: 598 LLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIKKIK 656
Query: 751 ITLGD 755
+TLGD
Sbjct: 657 LTLGD 661
>gi|2253205|emb|CAA71560.1| pbp2X [Streptococcus mitis]
Length = 666
Score = 629 bits (1622), Expect = e-178, Method: Composition-based stats.
Identities = 335/668 (50%), Positives = 474/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLN++L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGMESSLNTILAGTDGIITYEKDRVGNIVPGTEQVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS +KVM L+++I+N +F P+ Y N++ K+ D DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSALKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + S V M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSAVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ +KG S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFKGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|66817088|gb|AAY56843.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|66817090|gb|AAY56844.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 669
Score = 628 bits (1620), Expect = e-178, Method: Composition-based stats.
Identities = 336/673 (49%), Positives = 479/673 (71%), Gaps = 7/673 (1%)
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 1 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 60
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 61 SQPNLKQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLA 120
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK+
Sbjct: 121 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKD 179
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG
Sbjct: 180 VYTTISSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-IT 238
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGS +KVM L+++I+N +F P+ Y N++ K+ DV DW +N+
Sbjct: 239 EDFVWRDILYQSNYEPGSALKVMTLASSIDNNTF-PSGEYFNSSEFKIADVTTRDWDVND 297
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ G M+F QGF++SSNVGM++LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 298 GLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 357
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QMLRA TAI+N+G+MLEP+FI + DTN +VR ++KE+
Sbjct: 358 ADNIVNIAQSSFGQGISVTQTQMLRALTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEI 417
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+GKPVS+ AAS TR MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK
Sbjct: 418 VGKPVSEDAASLTRTNMILVGTDPIYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKN 477
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L
Sbjct: 478 GGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESL 537
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 538 NLQTTAKALEQVSKQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 597
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 598 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 656
Query: 743 LSKTKKITITLGD 755
+ KKIT+TLGD
Sbjct: 657 IKDIKKITLTLGD 669
>gi|23451785|gb|AAN32857.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
gi|23451788|gb|AAN32858.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 661
Score = 628 bits (1620), Expect = e-178, Method: Composition-based stats.
Identities = 335/665 (50%), Positives = 473/665 (71%), Gaps = 7/665 (1%)
Query: 94 DSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQV 153
D+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL QV
Sbjct: 1 DATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQV 60
Query: 154 SFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKD 213
SFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN+ D
Sbjct: 61 SFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-D 119
Query: 214 GSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAP 273
GS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE I+++ +DGK++YTT+S+P
Sbjct: 120 GSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQISQQTVDGKDVYTTISSP 179
Query: 274 LQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR 333
LQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG K + W +
Sbjct: 180 LQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITKDFVWRDI 238
Query: 334 LYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTM 393
LY++ YEPGS MKVM L+A+I+N +F P Y N++ +K+ DV I DW +NEG++ G M
Sbjct: 239 LYQSNYEPGSAMKVMTLAASIDNNTF-PGGEYFNSSELKIADVTIRDWDVNEGLTGGGMM 297
Query: 394 SFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIA 452
+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIA
Sbjct: 298 TFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIA 357
Query: 453 QSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQ 512
QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE++G PVSK
Sbjct: 358 QSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKD 417
Query: 513 AASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTN 572
AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK G Y VG
Sbjct: 418 AASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT 477
Query: 573 ETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLDTSVSEGS 632
+ S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ + S
Sbjct: 478 NYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKS 537
Query: 633 GK--TEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQI 690
+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+
Sbjct: 538 LEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQV 597
Query: 691 LIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKIT 750
LI++++ E+PDMYGWTK ETFAKW I++ ++G + TV KQ V A A+ KKIT
Sbjct: 598 LILSDKAEEVPDMYGWTKATAETFAKWLNIELEFEGSGT-TVQKQDVRANTAIKDIKKIT 656
Query: 751 ITLGD 755
+TLGD
Sbjct: 657 LTLGD 661
>gi|66817092|gb|AAY56845.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 666
Score = 628 bits (1620), Expect = e-178, Method: Composition-based stats.
Identities = 334/669 (49%), Positives = 474/669 (70%), Gaps = 7/669 (1%)
Query: 86 RNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQL 145
RNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 1 RNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQL 60
Query: 146 RTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRA 205
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A
Sbjct: 61 SQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLA 120
Query: 206 EPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKN 265
+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK+
Sbjct: 121 QLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKD 179
Query: 266 IYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAK 325
+YTT+S+PLQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG
Sbjct: 180 VYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-IT 238
Query: 326 KGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINE 385
+ + W + LY++ YEPGSTMKVM L+AAI+N +F P N++ +K+ D I DW +NE
Sbjct: 239 EDFVWRDILYQSNYEPGSTMKVMTLAAAIDNNTF-PGGEVFNSSELKIADATIRDWDVNE 297
Query: 386 GISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IV 444
G++ GR M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G +
Sbjct: 298 GLTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLP 357
Query: 445 SQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEV 504
+ N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KE+
Sbjct: 358 ADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEI 417
Query: 505 IGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKT 564
+G PVSK AAS TR M+ VGTDP +GT+YN S G P + V +VA+KSGTAQ+ DEK
Sbjct: 418 VGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKN 477
Query: 565 GTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATL 624
G Y VG + + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L
Sbjct: 478 GGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSL 537
Query: 625 D--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKE 682
+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +
Sbjct: 538 NLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGK 597
Query: 683 NIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEA 742
N+ N+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A
Sbjct: 598 NLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTA 656
Query: 743 LSKTKKITI 751
+ KKIT+
Sbjct: 657 IKDIKKITL 665
>gi|66817082|gb|AAY56840.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 667
Score = 628 bits (1620), Expect = e-178, Method: Composition-based stats.
Identities = 335/671 (49%), Positives = 472/671 (70%), Gaps = 7/671 (1%)
Query: 88 GNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRT 147
G +AED+TSY++YA++ Y S T + LYV+++QF+KVA++ L + ++Y QL
Sbjct: 1 GVPIAEDATSYNVYAVIDKKYKSATGKILYVEDAQFNKVAEVFHKYLDMDEAYVKEQLSQ 60
Query: 148 KGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEP 207
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+
Sbjct: 61 PNLTQVSFGAKGNGITYANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQL 120
Query: 208 IENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIY 267
EN+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK++Y
Sbjct: 121 HENE-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVY 179
Query: 268 TTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKG 327
TTLS+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG +
Sbjct: 180 TTLSSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITED 238
Query: 328 YDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGI 387
+ W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+G+
Sbjct: 239 FVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGL 297
Query: 388 SKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQ 446
+ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + +
Sbjct: 298 TTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPAD 357
Query: 447 NSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIG 506
N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G
Sbjct: 358 NIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVG 417
Query: 507 KPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGT 566
PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G
Sbjct: 418 NPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGG 477
Query: 567 YKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD- 625
Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+
Sbjct: 478 YLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNL 537
Query: 626 -TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENI 684
+ T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+
Sbjct: 538 QSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNL 597
Query: 685 KANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALS 744
N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+
Sbjct: 598 APNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIK 656
Query: 745 KTKKITITLGD 755
KKI +TLGD
Sbjct: 657 NIKKIKLTLGD 667
>gi|886957|emb|CAA88920.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 628 bits (1620), Expect = e-178, Method: Composition-based stats.
Identities = 334/668 (50%), Positives = 473/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMTIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNEGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSG AQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGAAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|154794050|gb|ABS86073.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 664
Score = 627 bits (1618), Expect = e-178, Method: Composition-based stats.
Identities = 335/666 (50%), Positives = 473/666 (71%), Gaps = 7/666 (1%)
Query: 81 GTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSY 140
GTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 2 GTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESY 61
Query: 141 TLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASE 200
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS
Sbjct: 62 VREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASS 121
Query: 201 FLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEA 260
F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++
Sbjct: 122 FIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQT 180
Query: 261 IDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTL 320
+DGK++YTT+S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT
Sbjct: 181 VDGKDVYTTISSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTK 240
Query: 321 EGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEIND 380
EG + + W + LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D D
Sbjct: 241 EG-ITEDFVWRDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRD 298
Query: 381 WSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGES 440
W +N+G++ G M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E
Sbjct: 299 WDVNDGLTTGGMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEY 358
Query: 441 SG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRT 499
+G + + N V+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR
Sbjct: 359 AGQLPADNIVSIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRK 418
Query: 500 AKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQV 559
++KE++G PVSK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+
Sbjct: 419 SQKEIVGNPVSKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQI 478
Query: 560 PDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMS 619
DEK G Y VG+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +
Sbjct: 479 ADEKNGGYLVGSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASA 538
Query: 620 MGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVS 677
M +L+ + T E+SY I +PGE A LR+N+V PIV+G G KI++ S
Sbjct: 539 MKESLNLQSPAKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETS 598
Query: 678 VDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
V+ N+ N+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V
Sbjct: 599 VEEGTNLAPNQQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDV 657
Query: 738 AAGEAL 743
A+
Sbjct: 658 RTNTAI 663
>gi|66817116|gb|AAY56857.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 666
Score = 627 bits (1618), Expect = e-178, Method: Composition-based stats.
Identities = 334/668 (50%), Positives = 476/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ T+
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKDSLNLQTT 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +N+ N
Sbjct: 540 AKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|2982614|emb|CAA05299.1| penicillin-binding protein 2x [Streptococcus mitis B6]
Length = 666
Score = 627 bits (1617), Expect = e-178, Method: Composition-based stats.
Identities = 333/668 (49%), Positives = 471/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 3 IAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQLAQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K KDA ++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 TQVSFGAKGNGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +GLE SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGLESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTM 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PL +F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLHSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ DV DW +N G++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKMADVTTRDWDVNGGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR +KE++GKPV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKYQKEIVGKPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
S+ AS TR MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SEDTASLTRTNMILVGTDPLYGTMYNHQTGKPIIIVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + + SVV M P+E+P++I+ VTVQ+P+ + +F NP+LE A +M +L+ ++
Sbjct: 480 GSTDYIFSVVTMNPAENPDFILSVTVQQPEHLSTPWFGEFANPILERASAMKDSLNLQST 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T +++Y I +PG+ A LR+N+V PIV+G G KI++ SV+ +N+ N
Sbjct: 540 AKTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKETSVEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDRVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|886955|emb|CAA88919.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 627 bits (1616), Expect = e-177, Method: Composition-based stats.
Identities = 334/668 (50%), Positives = 473/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMTIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS KVM+L+++I+N +F P+ Y N++ K+ D DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSAFKVMMLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNEGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVG ++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGTSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMY W K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYSWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|6689313|emb|CAB65441.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 627 bits (1616), Expect = e-177, Method: Composition-based stats.
Identities = 335/668 (50%), Positives = 473/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L G DG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+ LQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSTLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|1553051|emb|CAA67012.1| penicillin-binding protein [Streptococcus pneumoniae]
Length = 666
Score = 627 bits (1616), Expect = e-177, Method: Composition-based stats.
Identities = 334/668 (50%), Positives = 472/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 3 IAEDATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQLAQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG K GITY+ ++K KDA ++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 TQVSFGAKENGITYANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTFGLESSLNTILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT +G K + W
Sbjct: 182 SSPLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKDG-ITKDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY+ YEPGS MKVM L+++I+N +F P Y N++ K+ DV DW +NEG++ G
Sbjct: 241 RDILYQGNYEPGSAMKVMTLASSIDNNTF-PGGEYFNSSESKIADVTTRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVGM +LE+ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGMILLEEKMGDTTWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNDQTVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS+TR M+ VGTDP +GT+YN S G PI+ V +VA+KSGTAQ+ DEK G Y V
Sbjct: 420 SKDAASQTRTQMVLVGTDPVYGTMYNHSTGKPIVTVPGQNVALKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGAT--LDTS 627
G+ + S++ + P+E+P++I+YVTVQ+P+ ++ P+LE A +M + L +
Sbjct: 480 GSTNYIFSLLTINPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLYLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGDLAEELRRNIVQPIVVGTGTKIKESSVEEGRNLSPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK+ ETFAKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFEGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|47332|emb|CAA46263.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 627 bits (1616), Expect = e-177, Method: Composition-based stats.
Identities = 333/668 (49%), Positives = 475/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY + QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVIEQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE +++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F E+ K +AT+V+AKTGEILATTQRPT+++DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFQEKVKPKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGSTMKVM+L+AAI+N +F P+ Y N++ +K+ D I DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSTMKVMMLAAAIDNNTF-PSGEYFNSSELKIADATIRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+ QGF++SSNVGM++LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTLLQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIA S+FGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + D N T R ++KE++G PV
Sbjct: 360 NIAMSAFGQGISVTQTQMLRAFTAIANDGVMLEPKFISALYDPNDQTARKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS TR MI VGTDP +GT+YN S G P + V +VA+KSGTA++ DEK G Y V
Sbjct: 420 SKDAASLTRTNMILVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAEIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVVAM P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ T+
Sbjct: 480 GSTNNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFKNPILERASAMKDSLNLQTT 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +N+ N
Sbjct: 540 AKALEQVSQQSPYPMPSVKDISPGDLAEKLRRNLVQPIVVGTGTKIKNSSAEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK ETFAKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKAEEVPDMYGWTKATAETFAKWLNIELEFEGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|6689379|emb|CAB65448.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 626 bits (1615), Expect = e-177, Method: Composition-based stats.
Identities = 336/668 (50%), Positives = 471/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG K + W
Sbjct: 182 SSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITKDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+AAI+N +F P+ Y N++ K+ D DW +N G++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMTLAAAIDNNTF-PSGEYFNSSEFKIADATTRDWDVNAGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRA TAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRALTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
>gi|517191|emb|CAA55060.1| penicilin-binding protein [Streptococcus pneumoniae]
Length = 666
Score = 626 bits (1615), Expect = e-177, Method: Composition-based stats.
Identities = 334/668 (50%), Positives = 475/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+ LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSTLQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK+AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SKEAASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ T+
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKDSLNLQTT 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
+++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +N+ N
Sbjct: 540 AKALEQVGQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|23451782|gb|AAN32856.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 661
Score = 626 bits (1614), Expect = e-177, Method: Composition-based stats.
Identities = 334/665 (50%), Positives = 471/665 (70%), Gaps = 7/665 (1%)
Query: 94 DSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQV 153
D+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL QV
Sbjct: 1 DATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQV 60
Query: 154 SFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKD 213
SFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN+ D
Sbjct: 61 SFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-D 119
Query: 214 GSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAP 273
GS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTTLS+P
Sbjct: 120 GSKSLLGTSGMESSLNSILAGTDGIITYEKDRVGNIVPGTELVSQQTVDGKDVYTTLSSP 179
Query: 274 LQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR 333
LQ+F+ETQMD F+E+ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W +
Sbjct: 180 LQSFMETQMDAFLEKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVWRDI 238
Query: 334 LYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTM 393
LY++ YEPGS MKVM L+++I+N +F P+ Y N++ K+ D DW +N+G++ G M
Sbjct: 239 LYQSNYEPGSAMKVMTLASSIDNNTF-PSGEYFNSSEFKIADATTRDWDVNDGLTTGGMM 297
Query: 394 SFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIA 452
+F QGF++SSNVGM++LEQ MGD W +YL +KFG+PTRFG+ E +G + + N V+IA
Sbjct: 298 TFLQGFAHSSNVGMSLLEQKMGDATWLDYLKRFKFGVPTRFGLTDEYAGQLPADNIVSIA 357
Query: 453 QSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQ 512
QSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + DTN +VR ++KE++G PVSK+
Sbjct: 358 QSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGNPVSKE 417
Query: 513 AASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTN 572
AAS TRN+MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y VG+
Sbjct: 418 AASTTRNHMILVGTDPLYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLVGST 477
Query: 573 ETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSE 630
+ SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 478 NYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQSPAKN 537
Query: 631 GSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQI 690
T E+SY I +PGE A LR+N+V PIV+G G KI++ SV+ N+ N+Q+
Sbjct: 538 LDKVTTESSYAMPSIKDISPGELAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPNQQV 597
Query: 691 LIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKIT 750
L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ KKI
Sbjct: 598 LLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIKKIK 656
Query: 751 ITLGD 755
+TLGD
Sbjct: 657 LTLGD 661
>gi|154794056|gb|ABS86076.1| penicillin-binding protein 2x [Streptococcus pneumoniae]
Length = 669
Score = 625 bits (1611), Expect = e-177, Method: Composition-based stats.
Identities = 335/673 (49%), Positives = 474/673 (70%), Gaps = 7/673 (1%)
Query: 81 GTIYDRNGNVLAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSY 140
GTIYDRNG +AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY
Sbjct: 1 GTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESY 60
Query: 141 TLAQLRTKGAYQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASE 200
QL QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS
Sbjct: 61 VREQLSQPNLKQVSFGAKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASS 120
Query: 201 FLGRAEPIENKKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEA 260
F+G A+ EN+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++
Sbjct: 121 FIGLAQLHENE-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQT 179
Query: 261 IDGKNIYTTLSAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTL 320
+DGK++YTT+S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT
Sbjct: 180 VDGKDVYTTISSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTK 239
Query: 321 EGQAKKGYDWVNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEIND 380
EG K + W + LY++ YEPGS+MKVM L+AAI+N +F P N++ +KV D D
Sbjct: 240 EGLTKD-FVWRDILYQSNYEPGSSMKVMTLAAAIDNNTF-PGGEVFNSSELKVADTTTRD 297
Query: 381 WSINEGISKGRTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGES 440
W +NEG++ G M+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E
Sbjct: 298 WDVNEGLTGGGMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEY 357
Query: 441 SG-IVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRT 499
+G + + N VNIAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R
Sbjct: 358 AGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARK 417
Query: 500 AKKEVIGKPVSKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQV 559
++KEV+G PVSK AAS TR +M+ VGTDP +GT+YN G P + V +VA+KSGTAQ+
Sbjct: 418 SQKEVVGNPVSKDAASLTRTHMVLVGTDPVYGTMYNHKTGKPTVTVPGQNVALKSGTAQI 477
Query: 560 PDEKTGTYKVGTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMS 619
DEK G Y VG + S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +
Sbjct: 478 ADEKNGGYLVGLTNYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASA 537
Query: 620 MGATLD--TSVSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVS 677
M +L+ T+ ++++ Y + +PG+ A LR+NLV PIV+G G KI+ S
Sbjct: 538 MKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSS 597
Query: 678 VDAKENIKANEQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSV 737
+ +N+ N+Q+LI++++ E+PDMYGWTK E F+KW I++ ++G S TV KQ V
Sbjct: 598 AEEGKNLAPNQQVLILSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSGS-TVQKQDV 656
Query: 738 AAGEALSKTKKIT 750
A A+ KKIT
Sbjct: 657 RANTAIKDIKKIT 669
>gi|23451798|gb|AAN32862.1| penicillin-binding protein 2X [Streptococcus pneumoniae]
Length = 661
Score = 624 bits (1610), Expect = e-177, Method: Composition-based stats.
Identities = 334/665 (50%), Positives = 470/665 (70%), Gaps = 7/665 (1%)
Query: 94 DSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGAYQV 153
D+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL QV
Sbjct: 1 DATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQV 60
Query: 154 SFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIENKKD 213
SFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN+ D
Sbjct: 61 SFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENE-D 119
Query: 214 GSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTLSAP 273
GS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+S+P
Sbjct: 120 GSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSP 179
Query: 274 LQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDWVNR 333
LQ+F+ETQMD F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K + W +
Sbjct: 180 LQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITKDFVWRDI 238
Query: 334 LYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKGRTM 393
LY++ YEPGS MKVM L+AAI+N +F P N++ +KV DV DW +NEG++ G M
Sbjct: 239 LYQSNYEPGSAMKVMTLAAAIDNNTF-PGGEVFNSSELKVADVTTRDWDVNEGLTGGGMM 297
Query: 394 SFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSVNIA 452
+F+QGF++SSNVGMT+LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N VNIA
Sbjct: 298 TFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIA 357
Query: 453 QSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPVSKQ 512
QSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KEV+G PVSK
Sbjct: 358 QSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEVVGNPVSKD 417
Query: 513 AASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKVGTN 572
AAS TR +M+ VGTDP +GT+YN G P + V +VA+KSGTAQ+ DEK G Y VG
Sbjct: 418 AASLTRTHMVLVGTDPVYGTMYNHKTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT 477
Query: 573 ETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TSVSE 630
+ S V+M P+E+P++I+YVTVQ+P+ ++ NP+LE A +M +L+ T+
Sbjct: 478 NYIFSAVSMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKA 537
Query: 631 GSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKANEQI 690
++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +N+ N+Q+
Sbjct: 538 LEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQV 597
Query: 691 LIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTKKIT 750
LI++++ E+PDMYGWTK ETFAKW I++ ++G S TV KQ V A A+ KKIT
Sbjct: 598 LILSDKAEEVPDMYGWTKATAETFAKWLNIELEFQGSGS-TVQKQDVRANTAIKDIKKIT 656
Query: 751 ITLGD 755
+TLGD
Sbjct: 657 LTLGD 661
>gi|47308|emb|CAA46261.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 624 bits (1609), Expect = e-177, Method: Composition-based stats.
Identities = 333/668 (49%), Positives = 476/668 (71%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG + + W
Sbjct: 182 SSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS +KVM L+++I+N +F P+ Y N++ K+ DV DW +N+G++ G
Sbjct: 241 RDILYQSNYEPGSALKVMTLASSIDNNTF-PSGEYFNSSEFKIADVTTRDWDVNDGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F QGF++SSNVGM++LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFLQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIAQSSFGQGISVTQ QMLRA TAI+N+G+MLEP+FI + DTN +VR ++KE++GKPV
Sbjct: 360 NIAQSSFGQGISVTQTQMLRALTAIANDGVMLEPKFISAIYDTNNQSVRKSQKEIVGKPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
S+ AAS TR MI VGTDP +GT+YN G PII V +VAVKSGTAQ+ DEK G Y V
Sbjct: 420 SEDAASLTRTNMILVGTDPIYGTMYNHYTGKPIITVPGQNVAVKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G+ + SVV M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ T+
Sbjct: 480 GSTNYIFSVVTMNPAENPDFILYVTVQQPEHYSGIQLGEFATPILERASAMKESLNLQTT 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
++++ Y + +PG+ A LR+NLV PIV+G G KI+ S + +N+ N
Sbjct: 540 AKALEQVSKQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+LI++++ E+PDMYGWTK+ ET AKW I++ ++G S TV KQ V A A+ K
Sbjct: 600 QQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGS-TVQKQDVRANTAIKDIK 658
Query: 748 KITITLGD 755
KIT+TLGD
Sbjct: 659 KITLTLGD 666
>gi|6689315|emb|CAB65442.1| penicillin binding protein 2x [Streptococcus pneumoniae]
Length = 666
Score = 624 bits (1608), Expect = e-177, Method: Composition-based stats.
Identities = 331/668 (49%), Positives = 472/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AED+TSY++YA++ +Y S T + LYV+++QF+KVA++ L +++SY QL
Sbjct: 3 IAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GITY+ ++K + A +KG+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 KQVSFGSKGNGITYANMMSIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +G+E SLNS+L GTDG YEKD+ GN + GTE ++++ +DGK++YTT+
Sbjct: 123 E-DGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTI 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+ LQ+F+ETQM+ F E+ KG +AT+V+AKTGEILATTQRPT+++DT EG K + W
Sbjct: 182 SSTLQSFMETQMNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEG-ITKDFVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGSTMKVM L+++I+N +F P+ Y N++ K+ DV I DW +N G++ G
Sbjct: 241 RDILYQSNYEPGSTMKVMTLASSIDNNTF-PSGEYFNSSEFKIADVTIRDWDVNGGLTTG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
R M+F QGF+ SSNVGM++LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 RMMTFLQGFALSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
NIAQSSFGQGISVTQ QMLRAFTAI+N+G+MLEP+FI + D N TVR ++KE++G PV
Sbjct: 360 NIAQSSFGQGISVTQTQMLRAFTAIANDGVMLEPKFITALYDPNDQTVRRSQKEIVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS TR +M+ VGTDP +GT+YN G PII V +VAVKSGTA++ DEK G Y V
Sbjct: 420 SKDAASLTRTHMVLVGTDPRYGTMYNHGTGKPIITVPGQNVAVKSGTAEIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G + SVV+M P+E+P++I+YVT+Q+P+ ++ NP+LE A +M +L+ +
Sbjct: 480 GATNYIFSVVSMNPAENPDFILYVTIQQPEHYSVVHLGEFANPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV+ +N+ N
Sbjct: 540 AKNLEQVTAESSYAMPSIKDISPGDLAEALRRNIVQPIVIGTGTKIKESSVEEGKNLVPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ E FAKW I++ ++G S V +Q V A + K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAEAFAKWLDIELEFEGSGS-IVQQQDVRANTTIKNIK 658
Query: 748 KITITLGD 755
I +TLGD
Sbjct: 659 NIKLTLGD 666
>gi|2253207|emb|CAA71563.1| pbp2x [Streptococcus mitis]
Length = 666
Score = 623 bits (1607), Expect = e-176, Method: Composition-based stats.
Identities = 330/668 (49%), Positives = 468/668 (70%), Gaps = 7/668 (1%)
Query: 91 LAEDSTSYSIYAIVSTSYVSPTREKLYVQESQFDKVADILKDKLGIKKSYTLAQLRTKGA 150
+AE +TSY++YA++ Y S T + LYV++SQF+KVA++ L + ++Y QL
Sbjct: 3 IAEHATSYNVYAVIDKKYKSATGKILYVEDSQFNKVAEVFHKYLDMDEAYVKEQLAQPNL 62
Query: 151 YQVSFGLKGKGITYSVKEDLEKTFKDAGIKGMAFEATTSRMYPNGTFASEFLGRAEPIEN 210
QVSFG KG GIT++ ++K KDA ++G+ F + +R YPNG FAS F+G A+ EN
Sbjct: 63 TQVSFGAKGNGITHANMMAIKKDLKDASVEGIDFTTSPNRSYPNGQFASSFIGLAQLHEN 122
Query: 211 KKDGSYSLIGQTGLERSLNSLLTGTDGEAIYEKDKDGNTLLGTETITKEAIDGKNIYTTL 270
+ DGS SL+G +GLE SLN++L GTDG YEKD+ GN + GTE ++++ +DGK++YTTL
Sbjct: 123 E-DGSKSLLGTSGLESSLNTILAGTDGIITYEKDRVGNIVPGTEQVSQQTVDGKDVYTTL 181
Query: 271 SAPLQTFLETQMDTFMEQTKGINASATVVNAKTGEILATTQRPTYNSDTLEGQAKKGYDW 330
S+PLQ+F+ETQMD F+++ KG +AT+V+AKTGEILATTQRPT+N+DT EG + W
Sbjct: 182 SSPLQSFMETQMDAFLQKVKGKYMTATLVSAKTGEILATTQRPTFNADTKEG-ITEDLVW 240
Query: 331 VNRLYEAQYEPGSTMKVMLLSAAINNGSFNPNATYSNANGIKVGDVEINDWSINEGISKG 390
+ LY++ YEPGS MKVM L+AAI+N +F P Y N++ K+ DV DW +NEG++ G
Sbjct: 241 RDILYQSNYEPGSPMKVMSLAAAIDNNTF-PGGEYFNSSKFKMADVTTRDWDVNEGLTGG 299
Query: 391 RTMSFAQGFSYSSNVGMTMLEQAMGDKVWSNYLSLYKFGIPTRFGMVGESSG-IVSQNSV 449
M+F+QGF++SSNVGM++LEQ MGD W +YL+ +KFG+PTRFG+ E +G + + N V
Sbjct: 300 GMMTFSQGFAHSSNVGMSLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIV 359
Query: 450 NIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTVRTAKKEVIGKPV 509
+IAQSSFGQGISVTQ QM+RAFTAI+N+G+MLEP+FI + D N T R ++KEV+G PV
Sbjct: 360 SIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEVVGNPV 419
Query: 510 SKQAASETRNYMISVGTDPEFGTLYNKSEGSPIIQVGNNDVAVKSGTAQVPDEKTGTYKV 569
SK AAS TR +M+ VGTDP +GT+YN G P + V +VA+KSGTAQ+ DEK G Y V
Sbjct: 420 SKDAASLTRTHMVLVGTDPVYGTMYNHKTGKPTVTVPGQNVALKSGTAQIADEKNGGYLV 479
Query: 570 GTNETLNSVVAMVPSEDPEYIMYVTVQEPKTWNNNFFATVVNPVLEEAMSMGATLD--TS 627
G + + S V+M P+E+P++I+YVTVQ+P+ ++ P+LE A +M +L+ +
Sbjct: 480 GLTDYIFSAVSMNPAENPDFILYVTVQQPEHFSGIHLGEFATPILERASAMKESLNLQSP 539
Query: 628 VSEGSGKTEETSYQTGDIIGKTPGETANTLRQNLVHPIVLGVGNKIEKVSVDAKENIKAN 687
T E+SY I +PG+ A LR+N+V PIV+G G KI++ SV+ N+ N
Sbjct: 540 AKNLDKVTTESSYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKETSVEEGTNLAPN 599
Query: 688 EQILIMTNEFTELPDMYGWTKKNVETFAKWKGIKITYKGGKSGTVTKQSVAAGEALSKTK 747
+Q+L+++++ E+PDMYGW K+ ETFAKW I++ ++G S V KQ V A+ K
Sbjct: 600 QQVLLLSDKVEEIPDMYGWKKETAETFAKWLDIELEFEGSGS-VVQKQDVRTNTAIKNIK 658
Query: 748 KITITLGD 755
KI +TLGD
Sbjct: 659 KIKLTLGD 666
Database: nr
Posted date: Sep 17, 2007 11:41 AM
Number of letters in database: 999,999,834
Number of sequences in database: 2,976,859
Database: /nucleus1/users/jsaw/ncbi/db/nr.01
Posted date: Sep 17, 2007 11:48 AM
Number of letters in database: 894,087,890
Number of sequences in database: 2,493,262
Lambda K H
0.312 0.129 0.356
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,651,815,161
Number of Sequences: 5470121
Number of extensions: 113901791
Number of successful extensions: 262035
Number of sequences better than 1.0e-05: 500
Number of HSP's better than 0.0 without gapping: 540
Number of HSP's successfully gapped in prelim test: 1994
Number of HSP's that attempted gapping in prelim test: 251948
Number of HSP's gapped (non-prelim): 3217
length of query: 755
length of database: 1,894,087,724
effective HSP length: 141
effective length of query: 614
effective length of database: 1,122,800,663
effective search space: 689399607082
effective search space used: 689399607082
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 134 (56.2 bits)