1: prfB peptide chain release factor 2 [ Mycobacterium tuberculosis H37Rv ]
GeneID: 888820 updated 20-Dec-2008 - Gene name
- prfB
- Locus tag
- Rv3105c
- Gene type
- protein coding
- RefSeq status
- Validated
- Organism
- Mycobacterium tuberculosis H37Rv (strain: H37Rv)
- Lineage
- Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
- Also known as
- prfB
[Top][Help]Genomic regions, transcripts, and products
[Top][Help]General gene information- misc_feature
- Loc: c3473148-3473098 PS00745 Prokaryotic-type class I peptide chain release factors signature
[Top][Help]General protein information- Names
- peptide chain release factor 2
- NP_217621.1
- recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
[Top][Help]NCBI Reference Sequences (RefSeq)Genome Annotation
The following sections contain reference sequences that belong to a specific genome build. Explain This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.
mRNA and Protein(s)
NP_217621.1 peptide chain release factor 2 [Mycobacterium tuberculosis H37Rv]
- UniProtKB/Swiss-Prot
- P66026
- Conserved Domains (3) summary
- PRK00578
Location:9–376 Blast Score:1382
- prfB; peptide chain release factor 2; Validated
- cl02875
Location:233–345 Blast Score:362 Location:112–203 Blast Score:327
- RF-1; RF-1 domain
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