Gene name

prfB

Locus tag

Rv3105c

Gene type

protein coding

RefSeq status

Validated

Organism

Mycobacterium tuberculosis H37Rv (strain: H37Rv)

Lineage

Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex

Also known as

prfB

(minus strand) Go to reference sequence detailsTry our new Sequence Viewer

Related Articles in PubMed

GeneRIFs: Gene References Into FunctionWhat's a GeneRIF?

misc_feature

Loc: c3473148-3473098 PS00745 Prokaryotic-type class I peptide chain release factors signature

Names

peptide chain release factor 2

NP_217621.1

recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

mRNA and Protein(s)

1. NP_217621.1 peptide chain release factor 2 [Mycobacterium tuberculosis H37Rv]

   UniProtKB/Swiss-Prot

   P66026

   Conserved Domains (3) summary

   PRK00578
   Location:9–376
   Blast Score:1382

   prfB; peptide chain release factor 2; Validated

   cl02875
   Location:233–345
   Blast Score:362
   Location:112–203
   Blast Score:327

   RF-1; RF-1 domain