Pinheiro S, Orefice F, Salomao M, Castro-Neto M, Antunes C, Greco D; International Conference on AIDS.

Int Conf AIDS. 1992 Jul 19-24; 8: B109 (abstract no. PoB 3136).

School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.

OBJECTIVES: The frequency of ocular manifestations (OM) was studied in AIDS, AIDS-related complex (ARC) and HIV-seropositive patients (HIV+) and in seronegative persons (HIV-) at risk for infection. The association between the OM and immune status, measured by skin tests, was also assessed. METHODS: From March 90 to March 91, patients attended at the Infectious and Parasitic Diseases Service were examined at the Uveitis Clinic, submitted to slit-lamp examination and binocular indirect ophthalmoscopy with scleral depression under induced mydriasis. Those with ocular alterations were seen every two weeks. Clinicians and patients did not know clinical and laboratory status at eye examination. RESULTS: A total of 146 patients were examined; 110 (76%) were HIV+ and 36 (24%) were HIV-. The age ranged from 15 to 59 years, mean 30.3; 82% (120) were male and 18% (26) were female. The risk factor reported by 89 (61%) males was homo or bisexual behavior; 16 (11%) were intravenous drug users, 2 presented both factors, 6 had been blood transfused and 7 denied any risk. Heterosexual infection was presumed in 26 (18%, 2 men and 24 women whose sexual partners had AIDS). The most common OM was retinal microvasculopathy, present in 11% of those with AIDS, 25% of those with ARC, 2% of the asymptomatic HIV+ and 2% of the HIV- group. Toxoplasma retinitis was the most frequent opportunistic infection in patients with AIDS (9%), followed by tuberculous choroiditis (7%) and cytomegalovirus retinitis (7%). Kaposi's sarcoma and primary vitritis, found at slit-lamp examination, was diagnosed in 13% of AIDS patients. Patients with negative skin tests (various antigens), presented higher frequency of OM when compared to those with a positive test: AIDS, 64 and 36%; ARC, 38 and 9%; asymptomatic HIV+, 22 and 0%. CONCLUSIONS: (1) tuberculous choroiditis in AIDS patients was more frequent than previously reported and (2) HIV infected patients with negative skin tests presented a higher proportion of OM.

Publication Types:

• Meeting Abstracts

Keywords:

• AIDS-Related Complex
• Acquired Immunodeficiency Syndrome
• Bisexuality
• Brazil
• Female
• HIV Infections
• HIV Seropositivity
• Humans
• Male
• Risk Factors
• Sarcoma, Kaposi
• Sexual Partners
• Substance Abuse, Intravenous
• Tuberculosis

Other ID:

• 92400869

UI: 102198582

From Meeting Abstracts