Genetius Departamnt
Univertity of wisuon~~ln
Madison, Wimonsin

Mamh 2, 19%

Dr. E. 3. Anderson
Central Entaric Eeferencre Laboratory
Collandale Ammue
London, B, W. 9
ENGLAND

Bear Andyr

  Itwaer a greatpleamxre tohearfromyou on the laatreclordingre-
eeived some little while ago,  It wa8 technically very satisfactory,
and I atnglad tohearthdPtoursworked outinths sanrewayo We expect
to continue the exchange before ~~ryZoaa(,butIwanted towrite this
letter right away in order to answer one or two of the quelstions that
you brought up.  I was mrprimd whenyoubroughtme up on the mttm-
of the tramduuing activity of the other phagerr. I had been sure tht
I mu&have writtuntoyou about&but1 aearchsdxyfile ami sure
enough I had let it go by. Ny apolog3.m.

  What1 have to mportia notveryenlightening, A8 you alreadyknew,
k is quite actitre.  The other phages gave no conclusive result, possibly
hau~e of their relatively low titer. At the mment, and for the lmt
coupld of ~lontha, I have been occupied more with col& than with M.monel3.a
but I wffl be getting back to thie again before too long, I must admit
that the bagis of my interest in some of these phageo was somwhat shat
tered with q understanding that their bc)st range yols oonsiderably more
limited even-than thatofthe phage 22. Hyprimaryconoern,aside from
trying to get some clue as to tha gemerallity of tramdualng autivity,
was to try to break away from the host range restrictions of the original
PhW-  Ae I may, and hope,alreadyhave told you ths Bphage %aor"ia
also qu%te effective but is as well more restricted in its host range
than th8 22.  I have,however,noted ooctasional plaques inpreparationa
of both 22 and baor 2~ artsaim of group C.  I an notatall sure that
theee represent the origzinal phage, and 333 any 8arntX Irave not yet
been able to grou them out in satisfactory titer nor yet to get
~arh?xluctione to group c.  If anythingmuch more c~lllss ctutofthls
( ~JTJ-~ -!-nt TTli' 'r?:lr,:
-.           ,/L-i. -`h't..Y*
.bo you th*I it. would be p&&ble to induce Bri Felix to && join
with ,you in on& O? your recordingse&io&? I'had. found some of our rmitten
correspondence quite interestia,g and this mighi b;t much more 80 if i.t. &uld "
be congenial to him.                                 
                                                             2`
  I have just sent Cll.~ a copy of'a 3Y3port .that summarizes some of our
more recent doings, and have asked h&n to pass this .around,
find its way to you.  Pl&~e give our best to all.      .J hope it will '

                            Yours sincerely,
                                           
                                            7;

..Jmg                           Joshua, Le$erberg