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Proc Natl Acad Sci U S A. 1978 December; 75(12): 6332–6336.
PMCID: PMC393176
Classifications and comparisons of multilocus recombination distributions
Samuel Karlin and Uri Liberman
Department of Mathematics, Stanford University, Stanford, California 94305
Abstract
Various classifications and representations of multilocus recombination structures are delineated based on generalized notions of linkage values and recombination rates. An important class of recombination distributions (called the count-location chiasma process) is parameterized by a distribution of the number of crossover events and, for each such crossover count, by a conditional distribution of crossover locations. A number of properties of this recombination structure are developed. A multilocus definition of a “natural” recombination range is set forth. Orderings among recombination distributions in the multilocus setting are also discussed. Comparisons are made in terms of complete linkage, free assortment and noninterference schemes serving as standards.
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Selected References
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