SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility
Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
ANAGNOSTOPOULOS CONSTANTINE E
(Last) (First) (Middle)
(Street)
(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
GENZYME CORP [ GENZ ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
06/30/2003
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Genzyme Biosurgery common stock (GZBX) 06/30/2003 J ( 1 ) 1494 D 0 0 D
Genzyme General common stock (GENZ) 06/30/2003 J ( 1 ) 73 A 0 21073 D
Genzyme General common stock (GENZ) 06/30/2003 J ( 1 ) 12 A 0 21085 D
Genzyme Molecular Oncology common stock (GZMO) 06/30/2003 J ( 1 ) 216 D 0 0 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Biosurgery DOP stock option (right to buy) 14.17 06/30/2003 J 1676 ( 2 ) 12/16/1994 12/16/2004 Genzyme Biosurgery common stock (GZBX) 1676 $0 0 D
Biosurgery DOP stock option (right to buy) 36.55 06/30/2003 J 2483 ( 2 ) 05/26/1999 ( 3 ) 05/16/2006 Genzyme Biosurgery common stock (GZBX) 2483 $0 0 D
Biosurgery DOP stock option (right to buy) 6.25 06/30/2003 J 4022 ( 2 ) 05/26/2002 ( 3 ) 05/26/2009 Genzyme Biosurgery common stock (GZBX) 4022 $0 0 D
Biosurgery DOP stock option (right to buy) 11.04 06/30/2003 J 7272 ( 2 ) 05/25/2000 ( 4 ) 08/26/2009 Genzyme Biosurgery common stock (GZBX) 7272 $0 0 D
Biosurgery DOP stock option (right to buy) 6.69 06/30/2003 J 8000 ( 2 ) 05/31/2002 ( 5 ) 02/09/2011 Genzyme Biosurgery common stock (GZBX) 8000 $0 0 D
Biosurgery DOP stock option (right to buy) 6.26 06/30/2003 J 2000 ( 2 ) 05/31/2002 05/31/2011 Genzyme Biosurgery common stock (GZBX) 2000 $0 0 D
Biosurgery DOP stock option (right to buy) 4.24 06/30/2003 J 18000 ( 2 ) 05/30/2005 ( 3 ) 05/30/2012 Genzyme Biosurgery common stock (GZBX) 18000 $0 0 D
Genzyme General DOP stock option (right to buy) 286.56 06/30/2003 J 82 ( 2 ) 12/16/1994 12/16/2004 Genzyme General common stock (GENZ) 82 $0 82 D
Genzyme General DOP stock option (right to buy) 739.13 06/30/2003 J 122 ( 2 ) 05/29/1997 ( 3 ) 05/16/2006 Genzyme General common stock (GENZ) 122 $0 122 D
Genzyme General DOP stock option (right to buy) 124.69 06/30/2003 J 151 ( 2 ) 05/18/1997 06/18/2007 Genzyme General common stock (GENZ) 151 $0 151 D
Genzyme General DOP stock option (right to buy) 62.35 06/30/2003 J 673 ( 2 ) 05/25/2000 ( 3 ) 05/26/2009 Genzyme General common stock (GENZ) 673 $0 673 D
Genzyme General DOP stock option (right to buy) 126.39 06/30/2003 J 198 ( 2 ) 05/26/2000 ( 3 ) 05/26/2009 Genzyme General common stock (GENZ) 198 $0 198 D
Genzyme General DOP stock option (right to buy) 223.26 06/30/2003 J 359 ( 2 ) 05/25/2000 ( 4 ) 08/26/2009 Genzyme General common stock (GENZ) 359 $0 359 D
Genzyme General DOP stock option (right to buy) 135.29 06/30/2003 J 395 ( 2 ) 05/31/2001 ( 5 ) 02/09/2011 Genzyme General common stock (GENZ) 395 $0 395 D
Genzyme General DOP stock option (right to buy) 274.32 06/30/2003 J 112 ( 2 ) 05/30/2002 05/31/2011 Genzyme General common stock (GENZ) 112 $0 112 D
Genzyme General DOP stock option (right to buy) 126.60 06/30/2003 J 98 ( 2 ) 05/31/2002 05/31/2011 Genzyme General common stock (GENZ) 98 $0 98 D
Genzyme General DOP stock option (right to buy) 85.75 06/30/2003 J 890 ( 2 ) 05/30/2003 05/30/2012 Genzyme General common stock (GENZ) 890 $0 890 D
Genzyme General DOP stock option (right to buy) 41.51 06/30/2003 J 1010 ( 2 ) 05/30/2003 ( 3 ) 05/30/2012 Genzyme General common stock (GENZ) 1010 $0 1010 D
Molecular Oncology DOP stock option (right to buy) 7.00 06/30/2003 J 2700 ( 2 ) 06/18/1997 06/18/2007 Genzyme Molecular Oncology common stock (GZMO) 2700 $0 0 D
Molecular Oncology DOP stock option (right to buy) 3.50 06/30/2003 J 12000 ( 2 ) 05/30/2000 ( 3 ) 05/26/2009 Genzyme Molecular Oncology common stock (GZMO) 12000 $0 0 D
Molecular Oncology DOP stock option (right to buy) 15.40 06/30/2003 J 2000 ( 2 ) 05/30/2002 05/31/2011 Genzyme Molecular Oncology common stock (GZMO) 2000 $0 0 D
Molecular Oncology DOP stock option (right to buy) 2.33 06/30/2003 J 18000 ( 2 ) 05/30/2003 ( 3 ) 05/30/2012 Genzyme Molecular Oncology common stock (GZMO) 18000 $0 0 D
Explanation of Responses:
1 . On June 30, 2003 all outstanding shares of Genzyme Biosurgery and Genzyme Molecular stock were exchanged for shares of Genzyme General Stock. Genzyme Biosurgery shareholders received .04914 of a share of Genzyme General stock for each Biosurgery share and Genzyme Molecular Oncology shareholders received .05653 of a share of Genzyme General stock for each Molecular Oncology share.
2 . On June 30, 2003 in relation to the elimination of Genzyme's tracking stock structure, all stock options of Genzyme Biosurgery and Genzyme Molecular were exchanged for stock options of Genzyme General. The exchange ratio was based on the closing prices of all three stocks on 6/30/03. Genzyme Biosurgery options were exchanged at a rate of .04945 and Genzyme Molecular Oncology options were exchanged at a rate of .05614.
3 . Options vest in 1/3 annual increments on the dates of the next three annual meetings of shareholders following the date of grant.
4 . Options vest in 1/3 annual increments for 3 years beginning 5/25/00.
5 . Options vest in 50% increments on May 31,2001 and May 31, 2002.
By: Susan P. Cogswell, Attorney-in-Fact 07/01/2003
** Signature of Reporting Person Date
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