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Index of Cleared Science Reviews

Index for Captan (Pc Code 081301)

Undated. Review. 22 Pages.
Toxicology Branch.
Preliminary Review of the Teratology and Selected
Toxicology Studies for Captan, Folpet, and Captafol.

August 27, 1973. Review. 3 Pages.
Ronald Ney. Ecological Effects Branch.
Environmental Chemistry Review for Captan. (N-[(trichloro-
methyl) thio] -4- cyclohexene -1,2- Dicarboximide.
Reg. No. 239-533. Chevron Chemical Co.

January 14, 1975. Review. 14 Pages.
Ronald Ney.
Environmental Chemistry Review for Captan
(N-((tri-chloromethyl)thio)-4-cyclohexene-1,2-dicarboximide.
Reg. No. - 239-533. Company Name - Ortho Chemical Co.

July 9, 1975. Review. 6 Pages.
Ronald Ney. Ecological Effects Branch.
Registration on Taro in Hawaii Only - Resubmission.

November 18, 1976. Memorandum. 1 Page.
David Ritter. Toxicology Branch.
Vetron letter of 6/17/76 re captan mutagenicity.

February 9, 1978. Memorandum. 5 Pages.
William Greear. Toxicology Branch.
Orthocide 4 Flowable
Caswell #159
EPA Registration # 239-2347
Acute oral, acute dermal, eye & dermal irritation
Acc.# 232498.

July 6, 1978. Review. 2 Pages.
R.W. Cook. Efficacy and Ecological Effects Branch.
Submission of "Updated Compilation" of EC Data.

July 14, 1978. Review. 2 Pages.
Ronald Ney. Efficacy and Ecological Effects Branch.
To Remove Leaf Feeding Restriction from Taro Label.

July 24, 1978. Memorandum. 12 Pages.
Chan S-L. Toxicology Branch.
NCI Oncogenicity Study on Captan.

December 29, 1978. Review. 7 Pages.
Emil Regelman. Environmental Fate Branch.
Reg. File No. 239-1246. Review for 6a2 Data Only.
Acc 232569, 232570.

May 29, 1979. Memorandum. 4 Pages.
D.J. Clegg. Government of Canada.
Validation of Acute Dust Inhalation Toxicity Study on
Vitavax Seed Protectant with Captan (IBT N8586)
Tox review 000758.

August 3, 1979. Memorandum. 3 Pages.
William Dykstra. Toxicology.
EPA Reg. #400-136; Vitavax HBM-25 for Soybeans;
Caswell #165A. Acc. #238226.
Tox review 000759.

February 21, 1980. Review. 5 Pages.
Herbert L. Manning. Environmental Fate Branch.
Reg. No. 239-EULT. Resubmission with Environmental
Chemistry Data.

March 13, 1980. Review. 4 Pages.
Sherell Sterling. Fungicide Herbicide Branch.
Captan 50-W
EPA File Symbol: 707-RAN (707-160)
Accession No. 241538. [Acute studies].

June 9, 1980. Memorandum. 3 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA Registration Number: 239-2382
Orthocide Soil Treater "X"
Accession number 241922. Eye irritation.

June 18, 1980. Memorandum. 9 Pages.
Pesticide Section. Toxicological Evaluation Div. Canada.
Validation of the Study: "Rat Teratogenic Study -
Captan, Difolatan and Phaltan."
IBT No. P-5397.

June 19, 1980. Memorandum. 2 Pages.
Irving Mauer. Toxicology Branch.
Completed Contractor Studies - Mutagenicity.

July 7, 1980. Memorandum. 2 Pages.
Gary Burin. Toxicology Branch.
Label Change for Orthocide 4 Flowable, EPA Reg. 239-2437.

July 9, 1980. Memorandum. 7 Pages.
Sherell Sterling. Fungicide-Herbicide Branch.
EPA Registration NO. 1352-18
Flo Pro C-R Seed Protectant
Acute oral, dermal, irritation
Acc 242447.

September 2, 1980. Memorandum. 7 Pages.
Sherell Sterling. Fungicide-Herbicide Branch.
Merpan 50 W.P.
EPA Registration No. 7001-260
Acute data
Accession No. 243112.

September 30, 1980. Final Report. 2 Pages.
Enviro Control, Inc.
Task 5. Development of Chemical/Physical Profile: Captan.

November 10, 1980. Memorandum. 2 Pages.
Irving Mauer. Toxicology Branch.
Completed Contractor Studies - Mutagenicity.

November 18, 1980. Memorandum. 8 Pages.
Dr. N. Platanow. Task Force for Re-Assessment of Chemical.
Audit and validation of the study: "Rabbit teratogenic study
captan and phaltan"
Study Number: J-5420
Pages 4-8 removed, registrant data.

November 25, 1980. Memorandum. 7 Pages.
Sherell Sterling. Fungicide-Herbicide Branch.
Flo Pro Seed Protectant.
EPA Registration No. 1352-18.
Acute Oral, Acute Dermal, Eye Skin Irritation, Corrosivity.
Acc. 243564.

December 12, 1980. Memorandum. 7 Pages.
C.E. Mendoza. Task Force for Reassessment of Chemical.
Task Force for Reassessment of Chemical Safety, Canada
Audit and validation: Additional information submitted by
Chevron Chemical Co. on May 8, 1980 regarding "Dominant
lethal studies with metepa and MMS, and Captan technical,
albino mice." IBT No.: 622/623-05998.

March 24, 1981. Memorandum. 11 Pages.
Environmental Fate Branch.
Comments on the Proposed Study: "Evaluation of Health
Effects of Captan on Chemical Industry Workers".
Pages 5-11 are not included - registrant data.

April 10, 1981. Memorandum. 4 Pages.
Sherell Sterling. Fungicide-Herbicide Branch.
Chevron Captan Technical
EPA Registration No.: 239-1246
Eye irritation data were submitted
Acc. No. 244716.

April 14, 1981. Memorandum. 3 Pages.
Sherell Sterling. Fungicide-Herbicide Branch.
Chevron Captan Technical 90%
EPA Registration No. 239-2351
Eye irritation data were submitted... change in signal word
Acc. No. 244716.

May 14, 1981. Memorandum. 4 Pages.
Sherell Sterling. Fungicide-Herbicide Branch.
Orthocide 92 Seed Protectant Concentrate
EPA Registration No. : 239-2396
An Eye Irritation study was submitted...
Acc. No. 244713
Tox review 001187.

June 15, 1981. Memorandum. 3 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA Registration Number 239-2137
Eye Irritation Study: Chevron; Socal 1459/39:26; July 27,'79
Tox review 002105.

July 23, 1981. Memorandum. 8 Pages.
Sherell Sterling. Fungicide-Herbicide Branch.
Orthocide 15 Dust
EPA Reg. No. 239-788
The registrant submitted an Eye Irritation study to support
a change from CAUTION to DANGER.
Tox review 001189.

August 20, 1981. Memorandum. 5 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA Registration Number 239-1046
Ortho Soybean Seed Protectant
Acc. 245606. Eye Irritation Study
Tox review 002039.

September 10, 1981. Memorandum. 5 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA Registration Number: 239-2457
ORTHO Soybean Seed Protectant (MO) 2X
Acc. 245629. Eye Irritation Study
Tox review 002049.

September 25, 1981. Memorandum. 6 Pages.
Sherell Sterling. Fungicide-Herbicide Branch.
Captan 50W
EPA Registration No. 11678-40
Acute oral, acute inhalation, eye and skin irritation
Acc. 245707.

November 5, 1981. Memorandum. 4 Pages.
B.T. Backus. Insecticide Rodenticide Branch.
EPA Reg. No. 239-2355 ORTHOCIDE METHOXYCHLOR 65-5 SEED
PROTECTANT. Eye irritation.
Acc. 245823.

February 12, 1982. Memorandum. 2 Pages.
William Schneider. Toxicology Branch.
Worst Case Teratology Risk for Captan in Dietary Single
Servings.

March 9, 1982. Memorandum. 4 Pages.
Deloris Graham. Fungicide-Herbicide Branch.
EPA Registration Number 239-2458. Orthocide Vitavax 20-20
Seed Protectant. Page 4 removed, draft label.
Tox review 004666.

March 29, 1982. Memorandum. 2 Pages.
William Schneider. Toxicology Branch.
Subacute Rat Study (11678-12, -1, -15, -40) on Captan,
Submitted as Miscellaneous Data
Acc. 243969.

April 15, 1982. Memorandum. 1 Page.
Orville Paynter. Toxicology Branch.
Review of Reproduction and Teratology Studies.

April 19, 1982. Memorandum. 1 Page.
Robert Zendzian. Toxicology Branch.
Dermal Absorption Protocol for Captan.

June 15, 1982. Memorandum. 3 Pages.
Edwin Budd. Toxicology Branch.
Unscheduled DNA Synthesis Mutagenicity Assay of Captan
Accession #244432.

July 28, 1982. Memorandum. 6 Pages.
Albin Kocialski. Toxicology Branch.
EPA Reg. Nos. 239-533 and 239-1246. Response to
Discussion Received from Chevron Chemical Company
Regarding Comments by Registration Division to
Chevron for the Purpose of Summarizing the Lifetime
Oncogenic Feeding Study of Captan. Acc. 244220 thru 244226.

October 4, 1982. Memorandum. 2 Pages.
Edwin Budd. Toxicology Branch.
Dietary Analysis Addendum to Mouse Spot Test of
Captan. Reg. No. 239-1246
'A mouse somatic cell mutation assay was performed by Litton
Bionetics, Project No. 20951, October, 1980 for Chevron
Chemical Company...'.

November 18, 1982. Memorandum. 1 Page.
Robert Zendzian. Toxicology Branch.
Captan, Dermal Penetration Study
Captan 50-WP: A Dermal Penetration Study in Rats
by Joseph S. Ader, July 26, 1982. Addendum to original
review. Acceptable rather than core-supplementary.
Tox review 004587.

January 27, 1983. Memorandum. 3 Pages.
Edwin Budd. Toxicology Branch.
Hamster Teratology Study of Captan. IRDC, 2/16/79,
Acc. No. 238658, Reg. No. 239-1246.

February 23, 1983. Memorandum. 3 Pages.
Edwin Budd. Toxicology Branch.
Captan Rabbit Teratology Study, Acc. No. 246624,
Reg. No. 239-1246.

May 13, 1983. Memorandum. 3 Pages.
Edwin Budd. Toxicology Branch.
Interim Final Reports for Oral Carcinogenicity
Study with Merpan (Captan) in Rats. #11678-12.
Acc. 249781.

July 21, 1983. Memorandum. 17 Pages.
Edwin Budd. Toxicology Branch.
EPA Reg. No. 239-1246. Captan. Review of "Two-Year
Oral Toxicity/Carcinogenicity Study of Captan in Rats."
IRDC; #153-097; June 23, 1982. Submitted by Stauffer
Chemical Company and Chevron Chemical Company. EPA
Accession No. 249335-249338 and 249731 (Additional Data).

August 12, 1983. Memorandum. 8 Pages.
Edwin Budd. Toxicology Branch.
Review of A Dermal Absorptuion Study in Rats
Captan 50-WP T-11008. Stauffer Chemical Co.
Pages 6-8 removed, registrant data.
Acc. 249333.

August 12, 1983. Memorandum. 8 Pages.
Edwin Budd. Toxicology Branch.
EPA Registration No. 239-1246. Captan. Review of
Three Generation Reproduction Study in Rats. IRDC, #
153-096, January 7, 1982. Submitted by Stauffer Chemical
Company and Chevron Chemical Company. EPA Accession
No. 249334.

November 17, 1983. Memorandum. 15 Pages.
Edwin Budd. Toxicology Branch.
EPA Registration No. 239-1246. CAPTAN. Review of a
Lifetime Oral Oncogenicity Study of Captan in Mice,
Bio/dynamics, Project No. 80-2491, April 6, 1983.
Submitted by Chevron Chemical Company, EPA Accession
Nos. 249942-249948.

January 4, 1984. Review. 6 Pages.
Samuel Creeger. Exposure Assessment Branch.
Reg. No. 7501-EUP-E. Use on Corn, Sorghum, and
Soybean Seeds.
Pages 3-6 are not included - draft labeling.

January 4, 1984. Review. 7 Pages.
Samuel Creeger. Exposure Assessment Branch.
Reg. No. 239-1246, 239-2351. Label Amendment
Pages 4-7 are not included - draft labeling.

January 6, 1984. Memorandum. 1 Page.
Edwin Budd. Toxicology Branch.
Captan, EPA registration No. 476-2099. Review of
miscellaneous data. (Revised pages and historical rat
control data for IRDC rat carcinogenicity study. Submitted
by Stauffer Chemical Co. June 15, 1983. Acc. 250667, 250668.
Tox review 004520.

April 19, 1984. Memorandum. 3 Pages.
William Schneider. Toxicology Branch.
Captan and Captafol Memtabolite Deferral from Residue
Chemistry Branch associated with petitions 3F2893/3H5400,
accession # 071623.

June 22, 1984. Memorandum. 4 Pages.
William Schneider. Toxicology Branch.
Addendum to Clements' Review of Captan:
Robens, J.F., 1970, Teratogenic Activity
of Several Phtalimide Derivatives in the
Golden Hamster. Toxicology Appl. Pharmocol... Acc. 238658
Tox review 004454.

July 23, 1984. DER. 4 Pages.
William Schneider. Toxicology Branch.
Effects of Cysteine and a Liver Metabolic Activation System
on the Activities of Mutagenic Pesticides.
[... page 3] Sister-Chromatid Exchanges and Chromosomal
Aberrations in Cultured Chinese Hamster Cells...

September 26, 1984. Memorandum. 13 Pages.
E. Neil Pelletier. Science Support Branch.
Supplemental Information for Captan Exposure Analysis.

September 28, 1984. Memorandum. 1 Page.
William Schneider. Toxicology Branch.
Captan tolerances: 9E2250 / 7E1982 / 9E2251
Parsley, Dill, Taro
'Toxicology Branch cannot support additional tolerances
for captan as proposed by 9E2250, 7E1982, and 9E2251.'.

October 9, 1984. Memorandum. 7 Pages.
Harold Day. Exposure Assessment Branch.
Revised and Supplemental Captan Exposure.

October 15, 1984. Memorandum. 18 Pages.
Herbert Lacayo. Toxicology Branch.
Revised Captan, PD 2/3, Quantitative Risk Assessment.

October 16, 1984. Memorandum. 5 Pages.
Herbert Lacayo. Toxicology Branch.
Update to Captan Risk Assessment Due to revised and
Supllemented Captan Exposure Assessment.

November 19, 1984. Memorandum. 6 Pages.
William Schneider. Toxicology Branch.
Addendum to Toxicology Chapter, PD 2/3, Concerning
Deletion of Reproduction Study Requirements.

April 12, 1985. Memorandum. 15 Pages.
Jane Harris. Toxicology Branch.
Captan (Merpan) Lifetime (131-week)
Oncogenicity Study in Wistar rats; EPA ID #11678-1
Accession Number: 252722-252732
Tox review 004397.

May 17, 1985. Memorandum. 5 Pages.
Marion Copley. Toxicology Branch.
Registration #s: 11678-1,-2,-8,-9,-14,-40: Captan,
miscellaneous toxicity data for review
Accession No: 252584, 252585
Tox review 004451.

May 20, 1985. Memorandum. 16 Pages.
Marion Copley. Toxicology Branch.
Registration #'s: 239-1246, 239-2351; Captan; Registration
Amendment #239-912, Miscellaneous Toxicity Data.
Pages 3-6 removed, draft label.
Tox review 004463.

June 27, 1985. Memorandum. 2 Pages.
Marion Copley. Toxicology Branch.
Registration # 239-2351, Captan: Metabolism data.
Accession No. 256804.

July 2, 1985. Memorandum. 2 Pages.
Charles Trichilo. Residue Chemistry Branch.
Memo of Conference June 20, 1985 regarding Captan DCI
letter of 4/29/85.

July 12, 1985. Memorandum. 5 Pages.
William Schneider. Toxicology Branch.
Hampster Teratology Study of Captan. Amended
Final Report, IRDC, January 17, 1983,
Acc. No. 249681, Reg. No. 239-1246
Tox review 004548.

September 26, 1985. Memorandum. 3 Pages.
Marion Copley. Toxicology Branch.
I.D. Number 239-1246; Captan: Misc. data, hamster
teratology study.
Tox review 004692.

October 4, 1985. Memorandum. 4 Pages.
Philip Gray. FIFRA Scientific Advisory Panel.
Scientific Advisory Panel's Review of: 1) a set
of Scientific Issues Being Considered by the Agency
in Connection with the Special Review on Daminozide;
2) ... Issues... with the Special Review on Captan;
3) an Addendum to the Pesticide Assessment Guidelines...

October 17, 1985. Memorandum. 1 Page.
Marion Copley. Toxicology Branch.
Amendment to the Toxicology Branch chapter for the
captan registration standard.

October 21, 1985. Memorandum. 2 Pages.
Andrew Rathmman. Residue Chemistry Branch.
Memorandum of Conference, October 8, 1985
Protocol for Captan Poultry Feeding Study.

October 31, 1985. Memorandum. 3 Pages.
Lynn M. Bradley. Residue Chemistry Branch.
Captan. Alternative Program for Residue Reduction Data as
Required in Data Call-In Letter of April 29, 1985. No
Accession Number. RCB #59.

November 15, 1985. Memorandum. 9 Pages.
Andrew Rathmman. Residue Chemistry Branch.
EPA Registration No. 239-1246. Captan.
Response to April 29, 1985 Data Call-In
Letter Requesting Large Animal Feeding Study.
Accession No. 258867, RCB No. 1273.

November 19, 1985. Memorandum. 3 Pages.
Charles Trichilo. Residue Chemistry Branch.
Registration Standard for Captan
Method Trial Request.

December 2, 1985. Memorandum. 2 Pages.
Lynn Bradley. Residue Chemistry Branch.
EPA Reg. No. 476-2099. Captan. Poultry Feeding Protocol.
No Accession Number. RCB #183.

December 3, 1985. Memorandum. 4 Pages.
Charles Trichilo. Residue Chemistry Branch.
Captan Special Review--Review and Analysis
of Rebuttal Comments
No Accession Number RCB # 1420.

February 5, 1986. Memorandum. 5 Pages.
Marion Copley. Toxicology Branch.
E.P.A. ID No. 11678-1; Captan: Rat historical
control data for review. Accession No.: 260078
Tox review 004923.

February 19, 1986. Memorandum. 12 Pages.
Lynn Bradley. Residue Chemistry Branch.
Captan -- Stauffer and Chevron Response to Data Call-In
Letter - Validation Data for Market Basket Survey of
1977-1978 Accession Nos. 259155 and 258851. RCB Nos. 5 and
1449.

May 17, 1986. Memorandum. 15 Pages.
Marion Copley. Toxicology Branch.
I.D. Number 476-1819; Captan: Special Mouse Oncogenicity
Study.
Tox review 005126.

August 13, 1986. Memorandum. 5 Pages.
Charles Trichilo. Residue Chemistry Branch.
Stauffer Chemical Co. Response of 6/9/86 to Residue
Chemistry Data Requirements in the Captan Registration
Standard, issued March 1986. (RCB No. 1132; No Accession
Number).

August 21, 1986. Memorandum. 4 Pages.
Lynn Bradley. Residue Chemistry Branch.
Captan - Gustafson Detreated Seed Corn Study.
Accession No. 263378. RCB No. 1144.

September 4, 1986. Memorandum. 3 Pages.
Lynn Bradley. Residue Chemistry Branch.
EPA Registration No. 239-1246, Captan. June 9, 1986
Response to the Registration Standard Guidance Document.
No Accession Number. RCB 1132.

September 19, 1986. Memorandum. 6 Pages.
Andrew Rathman. Residue Chemistry Branch.
Captan. Addendum to Residue Reduction Data
Submitted in Response to 04/29/89 DCI Letter.
Accession No. 263843. RCB No. 1334.

October 23, 1986. Memorandum. 3 Pages.
A.R. Rathman. Residue Chemistry Branch.
EPA Reg. No. 7501-24. Captan. Protocol for Seed
Detreatment Studies. No Accession Number.
RCB Nos. 1430 and 1486.

October 23, 1986. Memorandum. 10 Pages.
Charles Trichilo. Residue Chemistry Branch.
List of Pesticides for which IR-4 Needs Residue
Chemical Information Before the Commencing of
Tolerance Petition Actions (Per Drew Baker Letter
Request of July 24, 1986) RCB No. 1295.

November 5, 1986. Memorandum. 20 Pages.
Marion Copley. Toxicology Branch.
Registration #239-2351, Captan: Resubmission of Metabolism
Data. Pages 16-20 removed, registrant data.
Tox review 005571.

November 19, 1986. Memorandum. 3 Pages.
Lynn Bradley. Residue Chemistry Branch.
Captan Registration Standard Data Requirements. Chevron
Letters of 8/22/86 and 10/08/86. No Accession Numbers.
RCB No. 1612 and 1613.

December 29, 1986. Memorandum. 19 Pages.
Reto Engler. Toxicology Branch.
Peer Review of Captan; Caswell No.: 159.
Tox Review No. 007715.

January 13, 1987. Review. 8 Pages.
Carolyn K. Offutt. Exposure Assessment Branch.
Evaluate Reentry Data for Captan Registration Standard -
Use on Strawberries and Apples.

April 16, 1987. Memorandum. 4 Pages.
Charles Trichilo. Residue Chemistry Branch.
Registration Standard for Captan.
Evaluation of Method Tryout Report.
(No MRID No.) [No RCB No.].

April 27, 1987. Memorandum. 2 Pages.
J. Garbus. Residue Chemistry Branch.
EPA No. (11678-1): Captan Technical: Additional Product
Chemistry Data for Makhteshim Material in Response to
Registration Standard. MRID Nos. 400217-01, 400660-01;
RCB No. 2120.

August 28, 1987. Memorandum. 2 Pages.
Richard Loranger. Residue Chemistry Branch.
EPA Reg. No. 239-1246. Additional Product Chemistry Data
for Chevron Captan Technical in Response to Registration
Standard (MRID # 402318-01) [RCB# 2427].

December 14, 1987. Memorandum. 14 Pages.
Nan Gray. Residue Chemistry Branch.
Captan - Dietary Exposure Assessment.
Attachment(s) following:

July 8, 1987. Memorandum. 2 Pages.
Neil Pelletier. Benefits and Use Division.
Extent of Crops Treated with Captan.

*End of attachments*

December 22, 1987. Memorandum. 11 Pages.
Susan Stanton. Residue Chemistry Branch.
Captan - Dietary Exposure and Oncogenic Risk Assessment.

January 28, 1988. Memorandum. 10 Pages.
Harry Craven. Ecological Effects Branch.
Fish and Wildlife Risk Assessment for the Disposal of
Treated Seeds by Exaggerated Planting Rates.

April 22, 1988. Memorandum. 39 Pages.
Nan S. Gray. Residue Chemistry Branch.
Captan - Addendum to Registration Standard. RCB No. 2317.
MRID Nos. 401898-2 through - 24 and 400105-01.

July 8, 1988. Review. 10 Pages.
Paul Mastradone. Exposure Assessment Branch.
Reg. # 239-1246. Submission of Laboratory Volatility
Study. Pages 8-10 are not included - registrant data.

July 12, 1988. Review. 15 Pages.
Frank Davido. Exposure Assessment Branch.
Reg. No. 239-1246. Submission of Foliar Dissipation and
Exposure Data from Strawberry and Apple Crops.

July 20, 1988. Memorandum. 2 Pages.
Esther Rinde. Toxicology Branch.
Peer Review of Captan, Addendum.

August 1, 1988. Review. 17 Pages.
Paul Mastradone. Exposure Assessment Branch.
Submission of Hydrolysis and Photodegredation in Water
Studies. Pages 9-12 are not included - registrant data.

August 3, 1988. Final Report. 104 Pages.
Dynamac Corporation.
Captan Addendum. Task 1: Review and Evaluation of
Individual Studies. Pages 8-18, 25-40, 46-56, 61-70, 75-82
and 91-97 are not included - registrant data.

August 8, 1988. Review. 9 Pages.
Paul Mastradone. Exposure Assessment Branch.
Reg. No. 239-1246. Addendum to Standard.

August 18, 1988. Memorandum. 2 Pages.
Nan S. Gray. Residue Chemistry Branch.
Captan Metabolism Studies Submitted for Registration
Standard. RCB No. 4012. MRID No. 406580-02 through -06.

August 18, 1988. Memorandum. 2 Pages.
Nan S. Gray. Residue Chemistry Branch.
NRDC Comments on Captan PD 2/3.

August 30, 1988. Memorandum. 4 Pages.
Susan V. Hummel. Dietary Exposure Branch.
EBDC's (014505), Chlorothalonil (081901), and Captan
(081301); Comparison of Dietary Exposure Analyses.
[No MRID No., RCB Nos. 4273, 4274, and 4275].

November 2, 1988. Memorandum. 3 Pages.
Andrew Rathman. Dietary Exposure Branch.
Revised Dietary Exposure Assessment for Captan.

November 7, 1988. Memorandum. 39 Pages.
Marion Copley. Toxicology Branch.
EPA ID 239-1246: Captan: Review Rat Metabolism Study.
MRID 406580-01. Pages 14-17, 19-20, 27-39 removed,
registration data.
Tox review 006925.

January 10, 1989. Memorandum. 1 Page.
Andrew Rathman. Dietary Exposure Branch.
Captan Task Force Response to EPA's Notice of Intent to
Suspend Certain Captan Products.

March 17, 1989. Memorandum. 7 Pages.
Francis D. Griffith. Dietary Exposure Branch.
Captan - EPA Registration No. 239-1246 - Review of
Protocols for Apple and Grape Crop Field Trial Data and
Processing Study Data. (No MRID Number) [DEB No. 4925]
[HED Project No. 9-0786].

May 31, 1989. Memorandum. 3 Pages.
Leung Cheng. Dietary Exposure Branch.
239-1246. Captan on Blueberries. MRID #410391-01.
DEB #5148.

June 16, 1989. Memorandum. 2 Pages.
Richard Schmitt. Dietary Exposure Branch.
EPA Reg. No. 4-122. Bonide Complete Fruit Tree Spray
containing Captan. DEB No. 4870.

June 16, 1989. Memorandum. 2 Pages.
Richard Schmitt. Dietary Exposure Branch.
EPA Reg. No. 8590-563. Suspension of Captan Products.
Agway Liquid Fruit Tree Spray. DEB No. 4871.

October 6, 1989. Memorandum. 8 Pages.
Andrew Rathman. Dietary Exposure Branch.
Residue Data Review for Corn, Soybean, Beet, and Spinach
Seed Treatments with Captan, DEB No. 5589, EPA No. 239-
1246, MRID Nos. 411491-01 through -04.

December 18, 1989. Memorandum. 2 Pages.
Andrew Rathman. Dietary Exposure Branch.
Captan on Taro. IR-4 Request for Data Waiver.
No Accession / No MRID No. DEB #6055.

December 19, 1989. Memorandum. 8 Pages.
Andrew Rathman. Dietary Exposure Branch.
Residue Data Reflecting Aerial Versus Ground Spray
Applications of Captan on Foliar Crops.
DEB No.: 4203
MRID Nos.: 407454-01 through -09.

December 19, 1989. Memorandum. 8 Pages.
Andrew Rathman. Dietary Exposure Branch.
Captan - Storage Stability Studies for the Captan
Registration Standard.

December 29, 1989. Memorandum. 2 Pages.
Christine Olinger. Dietary Exposure Branch.
Review of Protocol for Captan Dairy Cow Feeding Study,
No. 10182-293, Record No. 255730, DEB No. 6051.

January 29, 1990. Memorandum. 7 Pages.
Christine L. Olinger. Dietary Exposure Branch.
Residue Data Review for Soybean and Wheat Seed Treatments
with Captan, Record No. 256461; ID No. 10182-293;
DEB No. 6142; MRID Nos. 413061-01 and -02.

February 13, 1990. Memorandum. 3 Pages.
Marion Copley. Toxicology Branch.
EPA ID 0120: Captan: 90-day rat inhalation study and
request for waiver on the 90-day rat dermal
inhalation study.
MRID 412344-01, -02.

May 18, 1990. Memorandum. 38 Pages.
Marion Copley. Toxicology Branch.
EPA ID 0120; Captan: 90-Day Rat Inhalation Study and
Request for Waiver on the 90-Day Rat Dermal Inhalation
Study. Tox Review 007938.

July 30, 1990. Memorandum. 6 Pages.
Christine Olinger. Dietary Exposure Branch.
Addendum to Residue Data for Captan Seed Treatments; EPA
Reg. No. 10182-293; MRID No. 414684-01; DEB No. 6691.

September 5, 1990. Memorandum. 3 Pages.
Jane Smith. Dietary Exposure Branch.
Captan. Response to Request for Aerial and Dilute Ground
Applications on Apricots, Cherries, Plums, Fresh Prunes,
and Nectarines. No Accession / No MRID No./ No DEB No.

October 2, 1990. Memorandum. 29 Pages.
R.B. Perfetti. Dietary Exposure Branch.
Chevron Chemical Co.: Response to the Captan
Reregistration Standard: Residue Chemistry Requirements
(MRID #s 406580-02, -03, -04, -05, and -06, and
413930-01, 414069-01, and 413865-01. DEB #s 6525 and 6526).

May 17, 1991. Memorandum. 3 Pages.
Edward Zager. Chemistry Branch II.
Captan. Amended Request for Reregistration Method
Validation Trials of Analytical Method No. 166. No
CBRS Number; no DP BARCODE.

June 19, 1991. Memorandum. 2 Pages.
Leung Cheng. Chemistry Branch.
TX-910007. Captan Seed Treatment on Peanuts. No MRID #
DEB # 8080.

June 26, 1991. Memorandum. 15 Pages.
Andrew Rathman. Chemistry Branch II.
Captan - Storage Stability Studies for the Captan
Registration Standard and Follow-Up to Seed Treatment
Residue Data; MRID No. 415576-01; Branch No. 6995; DP
Barcode No. 155338.

July 25, 1991. Memorandum. 3 Pages.
Arliene M. Aikens. Chemistry Branch.
OK910006. Sec. 24(c) Special Local Need Registration for
the Use of a Combination of Captan, PCNB and Thiophanate -
Methyl as a Peanut Seed Treatment.

July 29, 1991. Memorandum. 5 Pages.
Michael Metzger. Chemistry Branch.
Captan on Raspberries. Request for Review of Residue Data
in Anticipation of Forthcoming 24(c) SLN Registration.
No Accession Number / No MRID Number. CB No. 8292.

September 11, 1991. Memorandum. 9 Pages.
R. B. Perfetti. Chemistry Branch.
ICI Americas Inc.: Response to the Captan Reregistration
Standard: Plant Metabolism Studies (MRID #41746001,
CBRS #7583, Barcode D160608.).

January 2, 1992. Memorandum. 3 Pages.
Paul Chin. Toxicology Branch.
EPA ID # 10182-293: Captan Technical - Response to
ICI's comments to Agency questions on 1 year chronic
dog study (MRID No. 408936-04)
Tox review 008966.

January 17, 1992. Memorandum. 2 Pages.
Paul Chin. Toxicology Branch.
EPA ID # 081301: Captan - Review of acute dermal and
dermal irritation studies (MRID Nos. 164357 and 400214-
01).

February 24, 1992. Memorandum. 4 Pages.
Paul Chin. Toxicology Branch.
EPA ID # 10182-145: Captan Technical - Response to 24
(C) registration of captan for control of diseases in
raspberries and blackberries (caneberries).

March 2, 1992. Memorandum. 20 Pages.
Paul Chin. Toxicology Branch.
EPA ID # 081301: Captan Technical - Review of
metabolism study in rats (MRID Nos. 415054-01 to
415054-04). Pages 16-20 removed, registrant data.
Tox review 009330 excerpt.

April 27, 1992. DER. 3 Pages.
Nancy McCarrol. Clement Int'l for Toxicology Branch.
Mutagenicity: Multiple In Vitro Genetic Toxicity Studies
MRID 00124901.

April 27, 1992. DER. 7 Pages.
Nancy McCarrol. Clement Int'l for Toxicology Branch.
Mutagenicity: Salmonella typhimurium/Mammalian Microsome
_Mutagenicity Assay
MRID 00073207.

April 27, 1992. DER. 9 Pages.
Nancy McCarrol. Clement Intl for Toxicology Branch.
Study Type: Mutagenicity: Microbial Gene Mutation Assays
(without S9-Activation)
Pages 5-9 removed, registrant data.
Tox review 010716 excerpt.

April 27, 1992. DER. 14 Pages.
Nancy McCarrol. Clement Intl for Toxicology Branch.
Study Type: Mutagenicity: In Vivo Cytogenic Assay with Rats
Pages 9-14 removed, registrant data.
Tox review 010716 excerpt.

April 27, 1992. DER. 21 Pages.
Nancy McCarrol. Clement Intl for Toxicology Branch.
Study Type: Mutagenicity: Heritable Translocation Assay in
Mice. Pages 17-21 removed, registrant data.
Tox review 010716 excerpt.

April 27, 1992. DER. 20 Pages.
Nancy McCarrol. Clement Intl for Toxicology Branch.
Study Type: Mutagenicity: Salmonella typhimurium/Mammalian
Microsome Mutagenicity Assay
Pages 7-20 removed, registrant data.
Tox review 010716 excerpt.

June 15, 1992. Memorandum. 17 Pages.
Paul Chin. Toxicology Branch.
EPA ID # 081301: Captan Technical - Review of
Developmental Toxicity Study in Rabbits (MRID No.
41826901).

March 1, 1993. Memorandum. 6 Pages.
Jennifer Manley. Science Analysis Branch.
Captan: Revised Dietary Risk Evaluation Due to Final
Tolerance Revocations on Several Commodities.

August 6, 1993. Memorandum. 1 Page.
Jennifer Wintersteen. Science Analysis Branch.
Captan: DRES Memo on Final Tolerance Revocations on oranges
cranberries, crabapples, grapefruit, lemons, limes,
tangerines, rhubarb, quinces, and pineapples.

December 22, 1993. Memorandum. 3 Pages.
Paul Chin. Toxicology Branch.
EPA ID # 081301: Captan Technical - Review of
Mutagenicity Studies with Captan
MRID 00062982, 00131710, 00138762, 00073207, 149489, 124901.

January 31, 1994. Memorandum. 9 Pages.
George Ghali. Health Effects Division.
RfD/Peer Review Report of Captan.

March 1, 1994. Memorandum. 20 Pages.
Paul Chin. Toxicology Branch.
EPA ID # 081301: Captan - Review of I. In Vitro Dermal
Penetration Study, II. Metabolism Study (Pilot), and
III. Dermal Penetration Study (Pilot).
MRID 43074701, 43012902. Pages 9-10, 20 removed, RD.
Impurity info on page 17 not included. Tox review 010811.

March 15, 1994. Memorandum. 2 Pages.
James Rowe. Toxicology Branch.
Toxicological (Developmental toxicity) of animal and
plant metabolite of Captan:1,2,3,6-tetrahydrophtalimide
(THPI).

April 1, 1994. Memorandum. 3 Pages.
Christine L. Olinger. Chemistry Branch II.
The Metabolism Committee Meeting Held on February 22 and
March 1, 1994: Captan Plant and Animal Metabolism.

November 10, 1994. Memorandum. 17 Pages.
Jennifer Wintersteen. Science Analysis Branch.
Captan: Dietary Exposure Analysis in Support of the
Reregistration Eligibility Decision.

February 13, 1995. Memorandum. 13 Pages.
Paul Chin. Toxicology Branch.
081301: Captan - Response to Recommendations
made in the Health Effects Division RfD/Peer Review
Report (Jan. 31, 1994)
MRID 120315, 125293, 418269-01, 78622, 78623, 86803, 126348,
00130848. Tox review 011411.

February 21, 1995. Memorandum. 324 Pages.
Nguyen Thoa. Risk Characterization & Analysis Branch.
The HED Chapter of the Reregistration Eligibility
Decision Document (RED) for Captan... Case 0120,
Chemical Code 081301; Reg. Group A
Tox review 011423.

January 15, 1997. Memorandum. 2 Pages.
Bernice Fisher. Science Analysis Branch.
Captan - Revised Q1* (3/4's Interspecies
Scaling Factor), Low-Dose Mouse DIetary Study
for 96 weeks.

January 22, 1997. Memorandum. 49 Pages.
Stephen Schaible. Science Analysis Branch.
Addendum to Captan RED: DietaryRisk Assessment in Support
of the Reregistration Eligibility Document for Captan.

May 30, 1997. Memorandum. 6 Pages.
Paul Chin. Toxicology Branch.
Reevaluation of Developmental Toxicity Potential
of THPI (1, 2, 3, 6-tetrahydrophthalimide), an
animal and plant metabolite of Captan ...
Page 5 removed, registrant data.

October 1, 1997. Memorandum. 1 Page.
William L. Burnam. Health Effects Division.
Captan Q1* Revisited.

October 7, 1997. Memorandum. 11 Pages.
George Z. Ghali. Health Effects Division.
Captan...Hazard Identification Committee Report.

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