LOCUS NP_954477 533 aa linear BCT 21-JAN-2009
DEFINITION sensory box histidine kinase [Geobacter sulfurreducens PCA].
ACCESSION NP_954477
VERSION NP_954477.1 GI:39998526
DBSOURCE REFSEQ: accession NC_002939.4
KEYWORDS .
SOURCE Geobacter sulfurreducens PCA
ORGANISM Geobacter sulfurreducens PCA
Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
Geobacteraceae; Geobacter.
REFERENCE 1 (residues 1 to 533)
AUTHORS Methe,B.A., Nelson,K.E., Eisen,J.A., Paulsen,I.T., Nelson,W.,
Heidelberg,J.F., Wu,D., Wu,M., Ward,N., Beanan,M.J., Dodson,R.J.,
Madupu,R., Brinkac,L.M., Daugherty,S.C., DeBoy,R.T., Durkin,A.S.,
Gwinn,M., Kolonay,J.F., Sullivan,S.A., Haft,D.H., Selengut,J.,
Davidsen,T.M., Zafar,N., White,O., Tran,B., Romero,C.,
Forberger,H.A., Weidman,J., Khouri,H., Feldblyum,T.V.,
Utterback,T.R., Van Aken,S.E., Lovley,D.R. and Fraser,C.M.
TITLE Genome of Geobacter sulfurreducens: metal reduction in subsurface
environments
JOURNAL Science 302 (5652), 1967-1969 (2003)
PUBMED 14671304
REFERENCE 2 (residues 1 to 533)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (11-SEP-2004) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (residues 1 to 533)
AUTHORS Methe,B., Nelson,K.E., Eisen,J.A., Paulsen,I.T., Nelson,W.C.,
Heidelberg,J.F., Wu,D., Wu,M., Ward,N., Beanan,M.J., Dodson,R.J.,
Madupu,R., Brinkac,L.M., Daugherty,S.C., DeBoy,R.T., Durkin,A.S.,
Gwinn,M.L., Kolonay,J.F., Sullivan,S.A., Haft,D.H., Selengut,J.,
Davidsen,T.M., Zafar,N., White,O., Tran,B., Romero,C.,
Forberger,H.A., Weidman,J.M., Khouri,H.M., Feldblyum,T.V.,
Utterback,T.R., Van Aken,S.E., Lovley,D.R. and Fraser,C.M.
TITLE Direct Submission
JOURNAL Submitted (05-SEP-2003) The Institute for Genomic Research, 9712
Medical Center Dr, Rockville, MD 20850, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from AAR36827.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..533
/organism="Geobacter sulfurreducens PCA"
/strain="PCA"
/db_xref="taxon:243231"
Protein 1..533
/product="sensory box histidine kinase"
/calculated_mol_wt=60103
Region 21..119
/region_name="PAS"
/note="PAS domain; PAS motifs appear in archaea,
eubacteria and eukarya. Probably the most surprising
identification of a PAS domain was that in EAG-like
K+-channels. PAS domains have been found to bind ligands,
and to act as sensors for light and oxygen in...; cd00130"
/db_xref="CDD:29035"
Site order(30,34,40,55..58,85,90)
/site_type="other"
/note="putative active site"
/db_xref="CDD:29035"
Site order(52,56,64,67..68,97,99)
/site_type="other"
/note="heme pocket"
/db_xref="CDD:29035"
Region 152..293
/region_name="GAF"
/note="GAF domain; cl00853"
/db_xref="CDD:120176"
Region 197..533
/region_name="BaeS"
/note="Signal transduction histidine kinase [Signal
transduction mechanisms]; COG0642"
/db_xref="CDD:30987"
Region 316..373
/region_name="HisKA"
/note="Histidine Kinase A (dimerization/phosphoacceptor)
domain; Histidine Kinase A dimers are formed through
parallel association of 2 domains creating 4-helix
bundles; usually these domains contain a conserved His
residue and are activated via trans...; cd00082"
/db_xref="CDD:119399"
Site order(317,321,324,328,331,350,354,357,361,364,368)
/site_type="other"
/note="dimer interface"
/db_xref="CDD:119399"
Site 319
/site_type="phosphorylation"
/db_xref="CDD:119399"
Region 423..526
/region_name="HATPase_c"
/note="Histidine kinase-like ATPases; This family includes
several ATP-binding proteins for example: histidine
kinase, DNA gyrase B, topoisomerases, heat shock protein
HSP90, phytochrome-like ATPases and DNA mismatch repair
proteins; cd00075"
/db_xref="CDD:28956"
Site order(429,433,436,461,463,465,467..468,493..496,512,514,
519..520,522)
/site_type="other"
/note="ATP binding site"
/db_xref="CDD:28956"
Site 433
/site_type="other"
/note="Mg2+ binding site"
/db_xref="CDD:28956"
Site order(465,467,493,495)
/site_type="other"
/note="G-X-G motif"
/db_xref="CDD:28956"
CDS 1..533
/locus_tag="GSU3437"
/coded_by="complement(NC_002939.4:3781828..3783429)"
/note="Identified by match to protein family HMM PF00512;
match to protein family HMM PF00785; match to protein
family HMM PF01590; match to protein family HMM PF02518;
match to protein family HMM TIGR00229"
/transl_table=11
/db_xref="GeneID:2686873"
ORIGIN
1 mesehickll ldfaadwefw ldpegacryv spaceritgy rpdefmgeag llrrivhped
61 reaveshltd alanregvcp idfriitrtg evrwishhcq pvhdgagtfl grrgsnrdit
121 drmaaqeenr rlgglmerlv rvvqelsrar sldeitavvr taarelvsad gatfvlreng
181 ncfyadedai aplwkglrfp lercisgwvm lnrqaavied iyqdqripve ayrptfvqsl
241 amvpirgedp igaigtywar rhrpseqeis viqaladtts vamenvrvya dleqrvrert
301 ealetanrel eafgfsvshd lrgplrrldg ysrmlyedya drlegegrdi lirmirlatr
361 meqliddllr fsrsvkgevv heavnlsrla rsiarelsdg epgravdfii adgltvegdp
421 gllraameni lrnawkytap kenaviefgr cegegerlyf irdngvgfdm ahkdklfqpf
481 erlhdarafe gtgiglatvk riidrhggri waegtpgaga tfyftlpepg ges
//