Laporte A, Lamontagne F, Saint-Maurice J, Lot F; International Conference on AIDS.
Int Conf AIDS. 1998; 12: 630-1 (abstract no. 248/33192).
OBJECTIVES: To evaluate the number and the type of requests for PEP in the context of non occupational exposure to HIV and the attitudes and prescriptions of physicians, from July 1996 to June 1997, before the issue of French recommendations. METHODS: In July 1997, a questionnaire was sent to 1,604 physicians having reported more than one AIDS case in the past 3 years, asking for 1) the number of PEP requests (R) and number of PEP prescribed (P) in the last 12 months; 2) the description of the latest exposure with PEP prescription; 3) the attitude of physicians regarding prescription towards 5 theoretical exposure situations. RESULTS: 722 (45%) physicians answered to the survey and 678 questionnaires were available to be analysed. 1) Frequency of requests (R) and prescriptions (P): 26% of physicians had at least one request. The total number of R was 390 and the total of P was 165 (P/R = 42%). For sexual exposures, P/R = 104/278 = 37%. For parenteral exposures (IDU), P/R = 19/32 = 59%. For other exposures (needle injuries in public places, bites,...), P/R = 42/80 = 53%. 2) Description of the latest exposure with PEP prescription: 120 cases were described. The 82 sexual exposures concerned a condom breakage for 70% of cases and an unprotected intercourse for 30%. HIV status of partner was known in 78% of sexual exposures and in 38% of other exposures. 3) Attitude of physicians towards prescription: 91% agreed with PEP when partner's HIV infection was known, 34% if the partner had HIV infection risk factors (HIV status unknown), 5% only if a condom breakage occurred with an HIV+ partner, 6% whatever the exposure, 2% were against PEP in all cases. CONCLUSION: Most physicians were in favor of PEP prescriptions after evaluation of risk exposure. However this evaluation is not always easy to do and must lead to publish guidelines to help physicians in their therapeutic decisions.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Attitude
- Drug Therapy, Combination
- HIV Infections
- HIV Seropositivity
- Physicians
- Prescriptions, Drug
- Questionnaires
- drug therapy
- therapy
Other ID:
UI: 102230058
From Meeting Abstracts