BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= FNP_1966
(425 letters)
Database: nr
5,470,121 sequences; 1,894,087,724 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148324483|gb|EDK89733.1| dihydroorotase [Fusobacterium n... 838 0.0
gi|34762310|ref|ZP_00143314.1| Dihydroorotase [Fusobacteriu... 795 0.0
gi|19703762|ref|NP_603324.1| dihydroorotase [Fusobacterium ... 792 0.0
gi|26554243|ref|NP_758177.1| dihydroorotase [Mycoplasma pen... 501 e-140
gi|70726714|ref|YP_253628.1| dihydroorotase [Staphylococcus... 485 e-135
gi|73662880|ref|YP_301661.1| dihydroorotase [Staphylococcus... 481 e-134
gi|82750806|ref|YP_416547.1| dihydroorotase [Staphylococcus... 477 e-133
gi|15924191|ref|NP_371725.1| dihydroorotase [Staphylococcus... 476 e-133
gi|148267692|ref|YP_001246635.1| dihydroorotase, multifunct... 476 e-133
gi|49483364|ref|YP_040588.1| dihydroorotase [Staphylococcus... 476 e-132
gi|15615101|ref|NP_243404.1| dihydroorotase [Bacillus halod... 468 e-130
gi|27467795|ref|NP_764432.1| dihydroorotase [Staphylococcus... 464 e-129
gi|57866724|ref|YP_188350.1| dihydroorotase [Staphylococcus... 463 e-128
gi|23098944|ref|NP_692410.1| dihydroorotase [Oceanobacillus... 459 e-127
gi|16801017|ref|NP_471285.1| dihydroorotase [Listeria innoc... 457 e-127
gi|16803877|ref|NP_465362.1| dihydroorotase [Listeria monoc... 455 e-126
gi|149182325|ref|ZP_01860803.1| dihydroorotase [Bacillus sp... 454 e-126
gi|89208472|ref|ZP_01186977.1| Dihydroorotase multifunction... 452 e-125
gi|46908069|ref|YP_014458.1| dihydroorotase [Listeria monoc... 452 e-125
gi|30263891|ref|NP_846268.1| dihydroorotase [Bacillus anthr... 452 e-125
gi|47569516|ref|ZP_00240196.1| dihydroorotase [Bacillus cer... 452 e-125
gi|42782981|ref|NP_980228.1| dihydroorotase [Bacillus cereu... 452 e-125
gi|153196345|ref|ZP_01940715.1| dihydroorotase, multifuncti... 451 e-125
gi|152976249|ref|YP_001375766.1| dihydroorotase, multifunct... 451 e-125
gi|116873272|ref|YP_850053.1| dihydroorotase [Listeria wels... 451 e-125
gi|49478433|ref|YP_037950.1| dihydroorotase [Bacillus thuri... 450 e-125
gi|30021977|ref|NP_833608.1| dihydroorotase [Bacillus cereu... 448 e-124
gi|154685966|ref|YP_001421127.1| PyrC [Bacillus amyloliquef... 444 e-123
gi|124520886|ref|ZP_01695958.1| dihydroorotase, multifuncti... 441 e-122
gi|56419685|ref|YP_147003.1| dihydroorotase [Geobacillus ka... 440 e-122
gi|56964100|ref|YP_175831.1| dihydroorotase [Bacillus claus... 439 e-121
gi|1172784|sp|P46538|PYRC_BACCL Dihydroorotase (DHOase) >gi... 438 e-121
gi|52080152|ref|YP_078943.1| dihydroorotase [Bacillus liche... 436 e-120
gi|89098723|ref|ZP_01171605.1| dihydroorotase [Bacillus sp.... 435 e-120
gi|126649701|ref|ZP_01721937.1| dihydroorotase [Bacillus sp... 433 e-119
gi|138894677|ref|YP_001125130.1| Dihydroorotase [Geobacillu... 432 e-119
gi|69247602|ref|ZP_00604413.1| Dihydroorotase multifunction... 429 e-118
gi|90961173|ref|YP_535089.1| Dihydroorotase [Lactobacillus ... 419 e-115
gi|29376270|ref|NP_815424.1| dihydroorotase [Enterococcus f... 404 e-111
gi|68055452|ref|ZP_00539597.1| Dihydroorotase multifunction... 400 e-110
gi|16078614|ref|NP_389433.1| dihydroorotase [Bacillus subti... 400 e-109
gi|1346930|sp|P48795|PYRC_LACLE Dihydroorotase (DHOase) >gi... 384 e-105
gi|104774743|ref|YP_619723.1| Dihydroorotase [Lactobacillus... 382 e-104
gi|116514878|ref|YP_813784.1| Dihydroorotase [Lactobacillus... 380 e-104
gi|116618309|ref|YP_818680.1| Dihydroorotase [Leuconostoc m... 377 e-102
gi|58337652|ref|YP_194237.1| dihydroorotase [Lactobacillus ... 376 e-102
gi|148543363|ref|YP_001270733.1| dihydroorotase, multifunct... 374 e-102
gi|141553194|gb|ABI26403.2| dihydroorotase and related cycl... 374 e-102
gi|92089939|ref|ZP_01274858.1| Dihydroorotase multifunction... 371 e-101
gi|116494940|ref|YP_806674.1| Dihydroorotase [Lactobacillus... 370 e-100
gi|28379202|ref|NP_786094.1| dihydroorotase [Lactobacillus ... 369 e-100
gi|1514601|emb|CAA91003.1| dihydroorotase, carbamoylasparti... 367 1e-99
gi|81428564|ref|YP_395564.1| Dihydroorotase [Lactobacillus ... 365 4e-99
gi|116492117|ref|YP_803852.1| Dihydroorotase [Pediococcus p... 364 6e-99
gi|42519203|ref|NP_965133.1| dihydroorotase [Lactobacillus ... 359 1e-97
gi|116629728|ref|YP_814900.1| Dihydroorotase [Lactobacillus... 352 4e-95
gi|118586673|ref|ZP_01544111.1| dihydroorotase [Oenococcus ... 342 2e-92
gi|116490362|ref|YP_809906.1| Dihydroorotase [Oenococcus oe... 339 2e-91
gi|154505061|ref|ZP_02041799.1| hypothetical protein RUMGNA... 333 1e-89
gi|154483488|ref|ZP_02025936.1| hypothetical protein EUBVEN... 329 2e-88
gi|50842481|ref|YP_055708.1| dihydroorotase [Propionibacter... 329 2e-88
gi|109645922|ref|ZP_01369842.1| dihydroorotase, multifuncti... 326 2e-87
gi|147678146|ref|YP_001212361.1| dihydroorotase and related... 324 6e-87
gi|89895607|ref|YP_519094.1| hypothetical protein DSY2861 [... 320 8e-86
gi|134299538|ref|YP_001113034.1| dihydroorotase, multifunct... 315 3e-84
gi|106885627|ref|ZP_01352984.1| dihydroorotase, multifuncti... 314 6e-84
gi|20807969|ref|NP_623140.1| dihydroorotase [Thermoanaeroba... 310 1e-82
gi|114566809|ref|YP_753963.1| Dihydroorotase [Syntrophomona... 309 2e-82
gi|51892396|ref|YP_075087.1| dihydroorotase [Symbiobacteriu... 308 4e-82
gi|154500490|ref|ZP_02038528.1| hypothetical protein BACCAP... 305 3e-81
gi|106894186|ref|ZP_01361307.1| Dihydroorotase multifunctio... 302 3e-80
gi|89210242|ref|ZP_01188633.1| Dihydroorotase multifunction... 300 1e-79
gi|150391903|ref|YP_001321952.1| dihydroorotase, multifunct... 299 2e-79
gi|76796898|ref|ZP_00779247.1| Dihydroorotase multifunction... 298 3e-79
gi|34391543|gb|AAN61168.1| dihydroorotase [Sporosarcina psy... 298 4e-79
gi|125973469|ref|YP_001037379.1| dihydroorotase, multifunct... 298 5e-79
gi|85860057|ref|YP_462259.1| dihydroorotase [Syntrophus aci... 296 2e-78
gi|57234049|ref|YP_181913.1| dihydroorotase [Dehalococcoide... 294 9e-78
gi|73748889|ref|YP_308128.1| dihydroorotase [Dehalococcoide... 293 2e-77
gi|156869403|gb|EDO62775.1| hypothetical protein CLOLEP_003... 291 7e-77
gi|78043256|ref|YP_360333.1| dihydroorotase [Carboxydotherm... 291 8e-77
gi|27262402|gb|AAN87482.1| Dihydroorotase [Heliobacillus mo... 288 4e-76
gi|116624589|ref|YP_826745.1| dihydroorotase, multifunction... 288 6e-76
gi|83589731|ref|YP_429740.1| dihydroorotase, multifunctiona... 288 7e-76
gi|121535610|ref|ZP_01667416.1| dihydroorotase, multifuncti... 287 8e-76
gi|94971175|ref|YP_593223.1| dihydroorotase, multifunctiona... 287 9e-76
gi|118727644|ref|ZP_01576238.1| dihydroorotase, multifuncti... 286 2e-75
gi|139439776|ref|ZP_01773167.1| Hypothetical protein COLAER... 286 3e-75
gi|88607405|ref|YP_504862.1| dihydroorotase, multifunctiona... 284 7e-75
gi|145955299|ref|ZP_01804303.1| hypothetical protein CdifQ_... 283 1e-74
gi|126699130|ref|YP_001088027.1| dihydroorotase [Clostridiu... 283 1e-74
gi|73536332|pdb|1XRF|A Chain A, The Crystal Structure Of A ... 282 3e-74
gi|108762395|ref|YP_631705.1| dihydroorotase, multifunction... 282 3e-74
gi|95929149|ref|ZP_01311893.1| dihydroorotase, multifunctio... 282 3e-74
gi|154148442|ref|YP_001406526.1| dihydroorotase (DHOase) [C... 280 9e-74
gi|15606174|ref|NP_213551.1| dihydroorotase [Aquifex aeolic... 280 1e-73
gi|147669650|ref|YP_001214468.1| dihydroorotase, multifunct... 279 2e-73
gi|153853806|ref|ZP_01995162.1| hypothetical protein DORLON... 279 3e-73
gi|77919213|ref|YP_357028.1| dihydrooratase [Pelobacter car... 279 3e-73
gi|42520125|ref|NP_966040.1| dihydroorotase [Wolbachia endo... 278 3e-73
gi|99034628|ref|ZP_01314581.1| hypothetical protein Wendoof... 278 3e-73
gi|124515272|gb|EAY56782.1| Dihydroorotase [Leptospirillum ... 278 4e-73
gi|146296937|ref|YP_001180708.1| dihydroorotase, multifunct... 278 4e-73
gi|153005053|ref|YP_001379378.1| dihydroorotase, multifunct... 278 7e-73
gi|86158044|ref|YP_464829.1| dihydroorotase, multifunctiona... 275 3e-72
gi|58696674|ref|ZP_00372226.1| dihydroorotase [Wolbachia en... 275 4e-72
gi|109672522|ref|ZP_01374759.1| dihydroorotase [Campylobact... 275 4e-72
gi|148263914|ref|YP_001230620.1| dihydroorotase, multifunct... 272 3e-71
gi|154174272|ref|YP_001408031.1| dihydroorotase (DHOase) [C... 272 3e-71
gi|153815090|ref|ZP_01967758.1| hypothetical protein RUMTOR... 270 1e-70
gi|78222979|ref|YP_384726.1| Dihydroorotase multifunctional... 270 1e-70
gi|118474957|ref|YP_892610.1| dihydroorotase [Campylobacter... 270 1e-70
gi|145617877|ref|ZP_01773940.1| dihydroorotase, multifuncti... 270 1e-70
gi|58584703|ref|YP_198276.1| Dihydroorotase, PyrC [Wolbachi... 270 2e-70
gi|118444937|ref|YP_878886.1| dihydroorotase [Clostridium n... 270 2e-70
gi|56417026|ref|YP_154100.1| dihydroorotase [Anaplasma marg... 269 3e-70
gi|110599796|ref|ZP_01388029.1| dihydroorotase, multifuncti... 269 3e-70
gi|3122654|sp|P96081|PYRC_THEAQ Dihydroorotase (DHOase) >gi... 267 1e-69
gi|114778473|ref|ZP_01453317.1| dihydroorotase, multifuncti... 265 4e-69
gi|118746284|ref|ZP_01594231.1| dihydroorotase, multifuncti... 265 4e-69
gi|55980750|ref|YP_144047.1| dihydroorotase [Thermus thermo... 265 5e-69
gi|28201871|sp|Q9CGM7|PYRC_LACLA Dihydroorotase (DHOase) 264 8e-69
gi|46198734|ref|YP_004401.1| dihydroorotase [Thermus thermo... 263 1e-68
gi|57239363|ref|YP_180499.1| dihydroorotase [Ehrlichia rumi... 263 1e-68
gi|58617384|ref|YP_196583.1| Dihydroorotase [Ehrlichia rumi... 263 2e-68
gi|58579330|ref|YP_197542.1| Dihydroorotase [Ehrlichia rumi... 263 2e-68
gi|15673051|ref|NP_267225.1| dihydroorotase [Lactococcus la... 263 2e-68
gi|28210638|ref|NP_781582.1| dihydroorotase [Clostridium te... 263 2e-68
gi|145622709|ref|ZP_01778665.1| dihydroorotase, multifuncti... 263 2e-68
gi|39996374|ref|NP_952325.1| dihydroorotase, multifunctiona... 262 2e-68
gi|15893810|ref|NP_347159.1| dihydroorotase [Clostridium ac... 262 3e-68
gi|118580940|ref|YP_902190.1| dihydroorotase, multifunction... 262 4e-68
gi|153892127|ref|ZP_02013073.1| dihydroorotase, multifuncti... 261 6e-68
gi|115380674|ref|ZP_01467599.1| dihydroorotase [Stigmatella... 261 6e-68
gi|113941598|ref|ZP_01427388.1| dihydroorotase, multifuncti... 261 7e-68
gi|152966948|ref|YP_001362732.1| dihydroorotase, multifunct... 259 2e-67
gi|68171217|ref|ZP_00544622.1| Dihydroorotase multifunction... 259 2e-67
gi|110598189|ref|ZP_01386466.1| dihydroorotase, multifuncti... 259 2e-67
gi|73667255|ref|YP_303271.1| Dihydroorotase multifunctional... 259 3e-67
gi|88608169|ref|YP_506052.1| dihydroorotase, multifunctiona... 258 7e-67
gi|83816824|ref|YP_446303.1| Amidohydrolase family, putativ... 257 8e-67
gi|116511900|ref|YP_809116.1| Dihydroorotase [Lactococcus l... 256 2e-66
gi|94984609|ref|YP_603973.1| dihydroorotase, multifunctiona... 255 3e-66
gi|25028287|ref|NP_738341.1| dihydroorotase [Corynebacteriu... 255 3e-66
gi|125624314|ref|YP_001032797.1| putative dihydroorotase [L... 255 4e-66
gi|50954775|ref|YP_062063.1| dihydroorotase [Leifsonia xyli... 253 1e-65
gi|153955968|ref|YP_001396733.1| PyrC [Clostridium kluyveri... 253 1e-65
gi|29833406|ref|NP_828040.1| dihydroorotase [Streptomyces a... 253 2e-65
gi|21219987|ref|NP_625766.1| dihydroorotase [Streptomyces c... 252 3e-65
gi|119962159|ref|YP_948008.1| dihydroorotase, multifunction... 251 6e-65
gi|51243957|ref|YP_063841.1| dihydroorotase [Desulfotalea p... 250 1e-64
gi|72161459|ref|YP_289116.1| dihydroorotase [Thermobifida f... 250 1e-64
gi|19552823|ref|NP_600825.1| dihydroorotase [Corynebacteriu... 249 2e-64
gi|150015888|ref|YP_001308142.1| dihydroorotase, multifunct... 249 2e-64
gi|145295733|ref|YP_001138554.1| hypothetical protein cgR_1... 249 2e-64
gi|78188868|ref|YP_379206.1| dihydroorotase [Chlorobium chl... 249 2e-64
gi|153810616|ref|ZP_01963284.1| hypothetical protein RUMOBE... 249 3e-64
gi|91201691|emb|CAJ74751.1| similar to dihydroorotase [Cand... 249 3e-64
gi|150386853|ref|ZP_01925348.1| dihydroorotase, multifuncti... 248 4e-64
gi|15806126|ref|NP_294830.1| dihydroorotase [Deinococcus ra... 248 4e-64
gi|62426348|ref|ZP_00381476.1| COG0044: Dihydroorotase and ... 248 5e-64
gi|116749522|ref|YP_846209.1| dihydroorotase, multifunction... 248 6e-64
gi|38233919|ref|NP_939686.1| dihydroorotase [Corynebacteriu... 248 7e-64
gi|121541592|ref|ZP_01673341.1| Dihydroorotase [Candidatus ... 248 7e-64
gi|68548958|ref|ZP_00588426.1| Dihydroorotase multifunction... 246 2e-63
gi|67917689|ref|ZP_00511294.1| Dihydroorotase multifunction... 246 3e-63
gi|88856238|ref|ZP_01130898.1| dihydroorotase [marine actin... 245 4e-63
gi|156863623|gb|EDO57054.1| hypothetical protein CLOL250_02... 245 4e-63
gi|21673868|ref|NP_661933.1| dihydroorotase [Chlorobium tep... 245 5e-63
gi|28211974|ref|NP_782918.1| dihydroorotase [Clostridium te... 244 6e-63
gi|145219707|ref|YP_001130416.1| dihydroorotase, multifunct... 243 2e-62
gi|156719232|ref|ZP_02060876.1| dihydroorotase, multifuncti... 243 2e-62
gi|120403645|ref|YP_953474.1| dihydroorotase, multifunction... 243 2e-62
gi|110801777|ref|YP_698522.1| dihydroorotase, multifunction... 243 2e-62
gi|18310163|ref|NP_562097.1| dihydroorotase [Clostridium pe... 242 3e-62
gi|68552959|ref|ZP_00592342.1| Dihydroorotase multifunction... 241 5e-62
gi|145594397|ref|YP_001158694.1| dihydroorotase, multifunct... 241 5e-62
gi|119716656|ref|YP_923621.1| dihydroorotase, multifunction... 240 1e-61
gi|15827190|ref|NP_301453.1| dihydroorotase [Mycobacterium ... 240 1e-61
gi|116670812|ref|YP_831745.1| dihydroorotase, multifunction... 239 2e-61
gi|156742404|ref|YP_001432533.1| dihydroorotase, multifunct... 239 2e-61
gi|41407214|ref|NP_960050.1| dihydroorotase [Mycobacterium ... 239 3e-61
gi|145224328|ref|YP_001135006.1| dihydroorotase, multifunct... 239 3e-61
gi|118464737|ref|YP_882574.1| dihydroorotase [Mycobacterium... 239 3e-61
gi|148272967|ref|YP_001222528.1| putative dihydroorotase [C... 238 5e-61
gi|68536101|ref|YP_250806.1| dihydroorotase [Corynebacteriu... 238 5e-61
gi|118617397|ref|YP_905729.1| dihydroorotase PyrC [Mycobact... 238 6e-61
gi|110800858|ref|YP_695831.1| dihydroorotase, multifunction... 238 7e-61
gi|84496658|ref|ZP_00995512.1| dihydroorotase [Janibacter s... 238 7e-61
gi|15608521|ref|NP_215897.1| dihydroorotase [Mycobacterium ... 238 7e-61
gi|94987261|ref|YP_595194.1| Dihydroorotase and related cyc... 238 7e-61
gi|119883927|ref|ZP_01650175.1| dihydroorotase, multifuncti... 237 9e-61
gi|31792575|ref|NP_855068.1| dihydroorotase [Mycobacterium ... 237 1e-60
gi|78186875|ref|YP_374918.1| dihydroorotase [Pelodictyon lu... 236 3e-60
gi|118473601|ref|YP_887360.1| dihydroorotase [Mycobacterium... 235 3e-60
gi|54025592|ref|YP_119834.1| dihydroorotase [Nocardia farci... 235 4e-60
gi|148656975|ref|YP_001277180.1| dihydroorotase, multifunct... 234 8e-60
gi|119357147|ref|YP_911791.1| dihydroorotase, multifunction... 234 9e-60
gi|126434989|ref|YP_001070680.1| dihydroorotase, multifunct... 233 1e-59
gi|111024099|ref|YP_707071.1| dihydroorotase [Rhodococcus s... 233 2e-59
gi|108799331|ref|YP_639528.1| dihydroorotase, multifunction... 233 3e-59
gi|78358005|ref|YP_389454.1| dihydroorotase, multifunctiona... 233 3e-59
gi|67937862|ref|ZP_00530392.1| Dihydroorotase multifunction... 232 4e-59
gi|154508779|ref|ZP_02044421.1| hypothetical protein ACTODO... 231 9e-59
gi|149177848|ref|ZP_01856447.1| dihydroorotase, multifuncti... 231 1e-58
gi|23014542|ref|ZP_00054353.1| COG0044: Dihydroorotase and ... 229 3e-58
gi|148998423|ref|ZP_01825865.1| dihydroorotase [Streptococc... 228 8e-58
gi|15903097|ref|NP_358647.1| dihydroorotase [Streptococcus ... 228 8e-58
gi|15901032|ref|NP_345636.1| dihydroorotase [Streptococcus ... 227 1e-57
gi|148994517|ref|ZP_01823697.1| dihydroorotase [Streptococc... 227 1e-57
gi|77408051|ref|ZP_00784799.1| dihydroorotase, multifunctio... 227 1e-57
gi|148989199|ref|ZP_01820589.1| dihydroorotase [Streptococc... 227 1e-57
gi|77414500|ref|ZP_00790648.1| dihydroorotase, multifunctio... 226 2e-57
gi|77406304|ref|ZP_00783369.1| dihydroorotase, multifunctio... 226 2e-57
gi|117928507|ref|YP_873058.1| dihydroorotase, multifunction... 226 2e-57
gi|76788409|ref|YP_329756.1| dihydroorotase [Streptococcus ... 226 2e-57
gi|55821079|ref|YP_139521.1| dihydroorotase [Streptococcus ... 226 2e-57
gi|148985777|ref|ZP_01818905.1| dihydroorotase [Streptococc... 226 3e-57
gi|116627822|ref|YP_820441.1| Dihydroorotase [Streptococcus... 226 3e-57
gi|83312713|ref|YP_422977.1| Dihydroorotase and related cyc... 225 4e-57
gi|77410438|ref|ZP_00786799.1| dihydroorotase, multifunctio... 225 4e-57
gi|149025521|ref|ZP_01836454.1| dihydroorotase [Streptococc... 225 4e-57
gi|22537204|ref|NP_688055.1| dihydroorotase [Streptococcus ... 225 4e-57
gi|71903354|ref|YP_280157.1| dihydroorotase [Streptococcus ... 225 4e-57
gi|68235084|ref|ZP_00574123.1| Dihydroorotase multifunction... 224 1e-56
gi|111224610|ref|YP_715404.1| Dihydroorotase (DHOase) [Fran... 223 1e-56
gi|86741887|ref|YP_482287.1| dihydroorotase, multifunctiona... 223 2e-56
gi|118048214|ref|ZP_01516829.1| dihydroorotase, multifuncti... 221 7e-56
gi|146318656|ref|YP_001198368.1| dihydroorotase [Streptococ... 219 2e-55
gi|153938072|ref|YP_001392590.1| dihydroorotase, multifunct... 219 2e-55
gi|148381188|ref|YP_001255729.1| dihydroorotase [Clostridiu... 219 4e-55
gi|28493334|ref|NP_787495.1| dihydroorotase [Tropheryma whi... 219 4e-55
gi|144898212|emb|CAM75076.1| Dihydroorotase multifunctional... 218 6e-55
gi|28572555|ref|NP_789335.1| dihydroorotase [Tropheryma whi... 216 2e-54
gi|24379638|ref|NP_721593.1| dihydroorotase [Streptococcus ... 216 2e-54
gi|117923420|ref|YP_864037.1| dihydroorotase, multifunction... 216 3e-54
gi|154487393|ref|ZP_02028800.1| hypothetical protein BIFADO... 215 4e-54
gi|157076146|gb|ABV10829.1| dihydroorotase [Streptococcus g... 215 5e-54
gi|119025779|ref|YP_909624.1| dihydroorotase [Bifidobacteri... 215 5e-54
gi|94994197|ref|YP_602295.1| Dihydroorotase [Streptococcus ... 215 5e-54
gi|139473933|ref|YP_001128649.1| putative dihydroorotase [S... 214 6e-54
gi|125718055|ref|YP_001035188.1| Dihydroorotase, putative [... 214 9e-54
gi|19745971|ref|NP_607107.1| dihydroorotase [Streptococcus ... 214 1e-53
gi|94990276|ref|YP_598376.1| Dihydroorotase [Streptococcus ... 213 1e-53
gi|71910522|ref|YP_282072.1| dihydroorotase [Streptococcus ... 213 2e-53
gi|15674928|ref|NP_269102.1| dihydroorotase [Streptococcus ... 213 2e-53
gi|27380211|ref|NP_771740.1| dihydroorotase [Bradyrhizobium... 213 3e-53
gi|110638193|ref|YP_678402.1| dihydroorotase [Cytophaga hut... 211 9e-53
gi|86133737|ref|ZP_01052319.1| dihydroorotase, multifunctio... 210 1e-52
gi|89091929|ref|ZP_01164884.1| dihydroorotase, multifunctio... 209 2e-52
gi|150401534|ref|YP_001325300.1| dihydroorotase, multifunct... 209 3e-52
gi|94266019|ref|ZP_01289740.1| Dihydroorotase multifunction... 209 3e-52
gi|115525375|ref|YP_782286.1| dihydroorotase, multifunction... 209 4e-52
gi|23335063|ref|ZP_00120301.1| COG0044: Dihydroorotase and ... 208 5e-52
gi|76261203|ref|ZP_00768821.1| Dihydroorotase multifunction... 207 7e-52
gi|23465368|ref|NP_695971.1| dihydroorotase [Bifidobacteriu... 207 9e-52
gi|94270421|ref|ZP_01291736.1| Dihydroorotase multifunction... 207 1e-51
gi|94266976|ref|ZP_01290625.1| Dihydroorotase multifunction... 207 2e-51
gi|15669684|ref|NP_248497.1| dihydroorotase (pyrC) [Methano... 206 2e-51
gi|156450396|ref|ZP_02056776.1| dihydroorotase, multifuncti... 206 3e-51
gi|153900767|ref|ZP_02021327.1| dihydroorotase, multifuncti... 206 3e-51
gi|92117806|ref|YP_577535.1| dihydroorotase, multifunctiona... 204 8e-51
gi|77163895|ref|YP_342420.1| Dihydroorotase multifunctional... 204 8e-51
gi|124005864|ref|ZP_01690702.1| dihydroorotase [Microscilla... 204 1e-50
gi|85716405|ref|ZP_01047377.1| dihydroorotase [Nitrobacter ... 203 1e-50
gi|86749543|ref|YP_486039.1| dihydroorotase, multifunctiona... 202 3e-50
gi|75676198|ref|YP_318619.1| dihydroorotase [Nitrobacter wi... 202 3e-50
gi|148256074|ref|YP_001240659.1| dihydroorotase (DHOase) [B... 202 4e-50
gi|91977497|ref|YP_570156.1| dihydroorotase, multifunctiona... 202 5e-50
gi|150399090|ref|YP_001322857.1| dihydroorotase, multifunct... 201 7e-50
gi|83594521|ref|YP_428273.1| Dihydroorotase multifunctional... 201 8e-50
gi|150025167|ref|YP_001295993.1| Dihydroorotase [Flavobacte... 199 3e-49
gi|46581306|ref|YP_012114.1| dihydroorotase [Desulfovibrio ... 199 4e-49
gi|119713434|gb|ABL97496.1| dihydroorotase [uncultured mari... 199 4e-49
gi|83857918|ref|ZP_00951445.1| Dihydroorotase [Croceibacter... 199 4e-49
gi|120601513|ref|YP_965913.1| dihydroorotase, multifunction... 198 5e-49
gi|146300204|ref|YP_001194795.1| amidohydrolase [Flavobacte... 198 5e-49
gi|134098651|ref|YP_001104312.1| dihydroorotase, multifunct... 198 6e-49
gi|134045628|ref|YP_001097114.1| dihydroorotase, multifunct... 198 7e-49
gi|148643057|ref|YP_001273570.1| dihydroorotase, PyrC [Meth... 198 7e-49
gi|154253275|ref|YP_001414099.1| dihydroorotase, multifunct... 198 7e-49
gi|91763195|ref|ZP_01265159.1| dihydroorotase [Candidatus P... 197 9e-49
gi|45358572|ref|NP_988129.1| Dihydroorotase [Methanococcus ... 197 1e-48
gi|114771333|ref|ZP_01448753.1| dihydroorotase, multifuncti... 197 1e-48
gi|71083769|ref|YP_266489.1| dihydroorotase [Candidatus Pel... 197 1e-48
gi|146341413|ref|YP_001206461.1| dihydroorotase (DHOase) [B... 196 3e-48
gi|49475584|ref|YP_033625.1| dihydroorotase [Bartonella hen... 196 3e-48
gi|108804316|ref|YP_644253.1| dihydroorotase, multifunction... 196 3e-48
gi|89890732|ref|ZP_01202241.1| dihydroorotase [Flavobacteri... 195 4e-48
gi|88713516|ref|ZP_01107598.1| dihydroorotase [Flavobacteri... 195 5e-48
gi|83643448|ref|YP_431883.1| Dihydroorotase and related cyc... 195 6e-48
gi|121602852|ref|YP_989128.1| dihydroorotase family protein... 194 6e-48
gi|90423749|ref|YP_532119.1| dihydroorotase, multifunctiona... 193 2e-47
gi|73669289|ref|YP_305304.1| dihydroorotase [Methanosarcina... 193 2e-47
gi|39936181|ref|NP_948457.1| dihydroorotase [Rhodopseudomon... 192 2e-47
gi|87310856|ref|ZP_01092982.1| dihydroorotase [Blastopirell... 191 9e-47
gi|126664020|ref|ZP_01735014.1| dihydroorotase [Flavobacter... 191 1e-46
gi|15965056|ref|NP_385409.1| dihydroorotase [Sinorhizobium ... 189 2e-46
gi|49474244|ref|YP_032286.1| dihydroorotase [Bartonella qui... 189 3e-46
gi|88805747|ref|ZP_01121266.1| dihydroorotase, multifunctio... 189 3e-46
gi|67154892|ref|ZP_00416637.1| Dihydroorotase multifunction... 189 4e-46
gi|91217466|ref|ZP_01254425.1| dihydroorotase [Psychroflexu... 188 6e-46
gi|154247841|ref|YP_001418799.1| dihydroorotase, multifunct... 188 6e-46
gi|153010988|ref|YP_001372202.1| dihydroorotase, multifunct... 188 7e-46
gi|150402178|ref|YP_001329472.1| dihydroorotase, multifunct... 188 7e-46
gi|78486228|ref|YP_392153.1| Allantoinase [Thiomicrospira c... 187 8e-46
gi|114762042|ref|ZP_01441510.1| dihydroorotase, multifuncti... 187 1e-45
gi|77461536|ref|YP_351043.1| dihydroorotase [Pseudomonas fl... 187 1e-45
gi|120556665|ref|YP_961016.1| dihydroorotase, multifunction... 186 2e-45
gi|62179132|ref|YP_215549.1| allantoinase [Salmonella enter... 186 2e-45
gi|148558275|ref|YP_001257587.1| dihydroorotase, multifunct... 186 3e-45
gi|116251504|ref|YP_767342.1| putative dihydroorotase [Rhiz... 186 3e-45
gi|62317543|ref|YP_223396.1| dihydroorotase [Brucella abort... 186 4e-45
gi|16759498|ref|NP_455115.1| allantoinase [Salmonella enter... 185 4e-45
gi|23500344|ref|NP_699784.1| dihydroorotase [Brucella suis ... 185 4e-45
gi|17989014|ref|NP_541647.1| dihydroorotase [Brucella melit... 185 5e-45
gi|90417724|ref|ZP_01225636.1| dihydroorotase, multifunctio... 185 5e-45
gi|84489144|ref|YP_447376.1| PyrC [Methanosphaera stadtmana... 185 6e-45
gi|20089776|ref|NP_615851.1| dihydroorotase [Methanosarcina... 185 6e-45
gi|88802755|ref|ZP_01118282.1| Amidohydrolase family, putat... 184 7e-45
gi|13470873|ref|NP_102442.1| dihydroorotase [Mesorhizobium ... 184 8e-45
gi|126659103|ref|ZP_01730243.1| dihydroorotase [Cyanothece ... 184 9e-45
gi|114707189|ref|ZP_01440087.1| dihydroorotase [Fulvimarina... 184 1e-44
gi|78486171|ref|YP_392096.1| dihydroorotase, multifunctiona... 184 1e-44
gi|86357275|ref|YP_469167.1| probable dihydroorotase protei... 182 3e-44
gi|309886|gb|AAA25977.1| dihydroorotase-like 182 4e-44
gi|118590186|ref|ZP_01547589.1| dihydroorotase [Stappia agg... 182 4e-44
gi|15679138|ref|NP_276255.1| dihydroorotase [Methanothermob... 182 4e-44
gi|149119024|ref|ZP_01845504.1| dihydroorotase, multifuncti... 182 5e-44
gi|21228113|ref|NP_634035.1| dihydroorotase [Methanosarcina... 182 5e-44
gi|110832895|ref|YP_691754.1| dihydroorotase, multifunction... 182 5e-44
gi|23127916|ref|ZP_00109775.1| COG0044: Dihydroorotase and ... 181 6e-44
gi|28202256|sp|O27199|PYRC_METTH Dihydroorotase (DHOase) 181 6e-44
gi|15595598|ref|NP_249092.1| dihydroorotase [Pseudomonas ae... 181 7e-44
gi|84324488|ref|ZP_00972546.1| COG0044: Dihydroorotase and ... 181 7e-44
gi|149376910|ref|ZP_01894665.1| Dihydroorotase and related ... 181 7e-44
gi|67923382|ref|ZP_00516862.1| Dihydroorotase multifunction... 181 8e-44
gi|146284272|ref|YP_001174425.1| dihydroorotase, multifunct... 181 8e-44
gi|37523238|ref|NP_926615.1| dihydroorotase [Gloeobacter vi... 181 1e-43
gi|15888632|ref|NP_354313.1| dihydroorotase [Agrobacterium ... 180 1e-43
gi|126734669|ref|ZP_01750415.1| dihydroorotase, multifuncti... 180 2e-43
gi|116054132|ref|YP_788575.1| noncatalytic dihydroorotase-l... 180 2e-43
gi|152994579|ref|YP_001339414.1| dihydroorotase, multifunct... 179 2e-43
gi|86142218|ref|ZP_01060728.1| Dihydroorotase multifunction... 179 2e-43
gi|70733119|ref|YP_262892.1| dihydroorotase [Pseudomonas fl... 179 3e-43
gi|146305436|ref|YP_001185901.1| dihydroorotase, multifunct... 179 3e-43
gi|153833662|ref|ZP_01986329.1| dihydroorotase [Vibrio harv... 179 3e-43
gi|26246520|ref|NP_752559.1| allantoinase [Escherichia coli... 179 4e-43
gi|126664531|ref|ZP_01735515.1| Dihydroorotase and related ... 179 4e-43
gi|56751040|ref|YP_171741.1| dihydroorotase [Synechococcus ... 178 5e-43
gi|71736336|ref|YP_272775.1| dihydroorotase, multifunctiona... 178 5e-43
gi|117621557|ref|YP_857112.1| dihydroorotase [Aeromonas hyd... 178 6e-43
gi|126727775|ref|ZP_01743605.1| Dihydroorotase and related ... 178 7e-43
gi|145298696|ref|YP_001141537.1| Dihydroorotase [Aeromonas ... 177 8e-43
gi|86130310|ref|ZP_01048910.1| Dihydroorotase multifunction... 177 1e-42
gi|75906345|ref|YP_320641.1| dihydroorotase [Anabaena varia... 177 1e-42
gi|87120927|ref|ZP_01076819.1| Dihydroorotase multifunction... 177 2e-42
gi|22298208|ref|NP_681455.1| dihydroorotase [Thermosynechoc... 177 2e-42
gi|77976883|ref|ZP_00832350.1| COG0044: Dihydroorotase and ... 177 2e-42
gi|66043748|ref|YP_233589.1| dihydroorotase [Pseudomonas sy... 176 2e-42
gi|83941411|ref|ZP_00953873.1| dihydroorotase, multifunctio... 176 2e-42
gi|152986268|ref|YP_001345896.1| noncatalytic dihydroorotas... 176 3e-42
gi|119856459|ref|ZP_01637892.1| dihydroorotase, multifuncti... 176 3e-42
gi|83644543|ref|YP_432978.1| Dihydroorotase and related cyc... 176 3e-42
gi|10442820|gb|AAG15559.1| dihydro-orotase PyrC [Pseudomona... 176 3e-42
gi|83854888|ref|ZP_00948418.1| dihydroorotase, multifunctio... 176 3e-42
gi|82703597|ref|YP_413163.1| dihydroorotase, multifunctiona... 175 4e-42
gi|16128496|ref|NP_415045.1| allantoinase [Escherichia coli... 175 4e-42
gi|156977625|ref|YP_001448531.1| hypothetical protein VIBHA... 175 5e-42
gi|28872155|ref|NP_794774.1| dihydroorotase [Pseudomonas sy... 175 5e-42
gi|84515825|ref|ZP_01003186.1| dihydroorotase, multifunctio... 175 5e-42
gi|149275867|ref|ZP_01882012.1| dihydroorotase [Pedobacter ... 175 5e-42
gi|26991676|ref|NP_747101.1| dihydroorotase [Pseudomonas pu... 175 6e-42
gi|113475822|ref|YP_721883.1| dihydroorotase, multifunction... 175 6e-42
gi|75209184|ref|ZP_00709435.1| COG0044: Dihydroorotase and ... 175 6e-42
gi|126728287|ref|ZP_01744103.1| dihydroorotase, multifuncti... 174 8e-42
gi|149371377|ref|ZP_01890863.1| dihydroorotase [unidentifie... 174 9e-42
gi|148550075|ref|YP_001270177.1| dihydroorotase, multifunct... 174 9e-42
gi|126356572|ref|ZP_01713577.1| dihydroorotase, multifuncti... 174 9e-42
gi|75189575|ref|ZP_00702842.1| COG0044: Dihydroorotase and ... 174 1e-41
gi|118030324|ref|ZP_01501782.1| dihydroorotase, multifuncti... 174 1e-41
gi|156861462|gb|EDO54893.1| hypothetical protein BACUNI_014... 174 1e-41
gi|75514630|ref|ZP_00736885.1| COG0044: Dihydroorotase and ... 174 1e-41
gi|149926770|ref|ZP_01915030.1| dihydroorotase [Limnobacter... 174 1e-41
gi|58039719|ref|YP_191683.1| Dihydroorotase [Gluconobacter ... 173 1e-41
gi|110633711|ref|YP_673919.1| dihydroorotase, multifunction... 173 2e-41
gi|32474815|ref|NP_867809.1| dihydroorotase [Rhodopirellula... 173 2e-41
gi|83587037|ref|ZP_00925667.1| COG0044: Dihydroorotase and ... 173 2e-41
gi|114798896|ref|YP_760998.1| putative dihydroorotase [Hyph... 173 2e-41
gi|87308422|ref|ZP_01090563.1| dihydroorotase [Blastopirell... 173 2e-41
gi|83746226|ref|ZP_00943280.1| Aspartate carbamoyltransfera... 173 2e-41
gi|3914520|sp|Q59712|PYRX_PSEPU Dihydroorotase-like protein... 173 2e-41
gi|94501643|ref|ZP_01308159.1| Dihydroorotase and related c... 172 3e-41
gi|89093009|ref|ZP_01165960.1| Allantoinase [Oceanospirillu... 172 4e-41
gi|104783980|ref|YP_610478.1| dihydroorotase, multifunction... 172 4e-41
gi|75194725|ref|ZP_00704795.1| COG0044: Dihydroorotase and ... 172 4e-41
gi|121997733|ref|YP_001002520.1| dihydroorotase, multifunct... 172 4e-41
gi|114327471|ref|YP_744628.1| dihydroorotase [Granulibacter... 172 4e-41
gi|84684262|ref|ZP_01012164.1| Dihydroorotase and related c... 172 5e-41
gi|126740586|ref|ZP_01756273.1| dihydroorotase, multifuncti... 172 5e-41
gi|83952420|ref|ZP_00961151.1| dihydroorotase, multifunctio... 172 6e-41
gi|83310364|ref|YP_420628.1| Dihydroorotase and related cyc... 171 6e-41
gi|67906658|gb|AAY82748.1| predicted dihydroorotase [uncult... 171 6e-41
gi|86609956|ref|YP_478718.1| dihydroorotase [Synechococcus ... 171 6e-41
gi|84499770|ref|ZP_00998058.1| dihydroorotase, multifunctio... 171 6e-41
gi|120435808|ref|YP_861494.1| dihydroorotase-2 [Gramella fo... 171 6e-41
gi|99078050|ref|YP_611308.1| dihydroorotase, multifunctiona... 171 7e-41
gi|134294914|ref|YP_001118649.1| dihydroorotase, multifunct... 171 1e-40
gi|153886417|ref|ZP_02007572.1| dihydroorotase, multifuncti... 171 1e-40
gi|74318601|ref|YP_316341.1| dihydroorotase [Thiobacillus d... 171 1e-40
gi|91772776|ref|YP_565468.1| dihydroorotase, multifunctiona... 171 1e-40
gi|91776455|ref|YP_546211.1| dihydroorotase, multifunctiona... 171 1e-40
gi|91225711|ref|ZP_01260740.1| dihydroorotase [Vibrio algin... 170 1e-40
gi|86139056|ref|ZP_01057627.1| dihydroorotase, multifunctio... 170 1e-40
gi|152981059|ref|YP_001354636.1| dihydroorotase, multifunct... 170 1e-40
gi|53720299|ref|YP_109285.1| dihydroorotase [Burkholderia p... 170 2e-40
gi|99913859|ref|ZP_01320456.1| hypothetical protein Bpse1_0... 170 2e-40
gi|121531476|ref|ZP_01664081.1| dihydroorotase [Ralstonia p... 169 2e-40
gi|89070216|ref|ZP_01157544.1| dihydroorotase, multifunctio... 169 2e-40
gi|83719997|ref|YP_442012.1| aspartate carbamoyltransferase... 169 3e-40
gi|126439283|ref|YP_001060120.1| dihydroorotase, multifunct... 169 3e-40
gi|17545398|ref|NP_518800.1| dihydroorotase [Ralstonia sola... 169 3e-40
gi|148975881|ref|ZP_01812670.1| dihydroorotase [Vibrionales... 169 3e-40
gi|88812466|ref|ZP_01127715.1| dihydroorotase family protei... 169 3e-40
gi|76801502|ref|YP_326510.1| dihydroorotase [Natronomonas p... 169 3e-40
gi|88801694|ref|ZP_01117222.1| dihydroorotase [Polaribacter... 169 5e-40
gi|88854329|ref|ZP_01128996.1| Dihydroorotase and related c... 168 5e-40
gi|110680599|ref|YP_683606.1| dihydroorotase, multifunction... 168 5e-40
gi|17229795|ref|NP_486343.1| dihydroorotase [Nostoc sp. PCC... 168 8e-40
gi|56695199|ref|YP_165547.1| dihydroorotase, multifunctiona... 168 8e-40
gi|55378921|ref|YP_136771.1| dihydroorotase [Haloarcula mar... 167 9e-40
gi|146276278|ref|YP_001166437.1| dihydroorotase, multifunct... 167 1e-39
gi|53803471|ref|YP_114748.1| dihydroorotase family protein ... 167 1e-39
gi|119713295|gb|ABL97360.1| dihydroorotase [uncultured mari... 166 2e-39
gi|126463423|ref|YP_001044537.1| dihydroorotase, multifunct... 166 3e-39
gi|114330472|ref|YP_746694.1| dihydroorotase, multifunction... 166 4e-39
gi|116754418|ref|YP_843536.1| dihydroorotase, multifunction... 165 5e-39
gi|67923145|ref|ZP_00516634.1| Dihydroorotase multifunction... 165 5e-39
gi|86134691|ref|ZP_01053273.1| dihydroorotase [Tenacibaculu... 165 5e-39
gi|115350795|ref|YP_772634.1| dihydroorotase, multifunction... 165 6e-39
gi|118700383|ref|ZP_01558452.1| dihydroorotase, multifuncti... 165 6e-39
gi|153894488|ref|ZP_02015072.1| dihydroorotase, multifuncti... 164 7e-39
gi|118719650|ref|ZP_01572179.1| dihydroorotase, multifuncti... 164 8e-39
gi|42524106|ref|NP_969486.1| dihydroorotase [Bdellovibrio b... 164 1e-38
gi|119487285|ref|ZP_01621036.1| dihydroorotase [Lyngbya sp.... 164 1e-38
gi|113868867|ref|YP_727356.1| Dihydroorotase [Ralstonia eut... 164 1e-38
gi|86604904|ref|YP_473667.1| dihydroorotase [Synechococcus ... 164 1e-38
gi|86132453|ref|ZP_01051047.1| dihydroorotase [Cellulophaga... 164 1e-38
gi|30249628|ref|NP_841698.1| dihydroorotase [Nitrosomonas e... 164 1e-38
gi|150396158|ref|YP_001326625.1| dihydroorotase, multifunct... 164 1e-38
gi|116053692|ref|YP_794019.1| dihydroorotase [Pseudomonas a... 164 1e-38
gi|77464583|ref|YP_354087.1| Dihydroorotase and related cyc... 163 2e-38
gi|84318214|ref|ZP_00966642.1| COG0044: Dihydroorotase and ... 163 2e-38
gi|15600734|ref|NP_254228.1| dihydroorotase [Pseudomonas ae... 163 2e-38
gi|89056396|ref|YP_511847.1| dihydroorotase, multifunctiona... 163 2e-38
gi|118735068|ref|ZP_01583541.1| dihydroorotase, multifuncti... 163 2e-38
gi|56551688|ref|YP_162527.1| dihydroorotase [Zymomonas mobi... 163 2e-38
gi|152987886|ref|YP_001351654.1| probable dihydroorotase [P... 163 2e-38
gi|119487281|ref|ZP_01621032.1| dihydroorotase [Lyngbya sp.... 163 2e-38
gi|94972077|ref|YP_594117.1| dihydroorotase, multifunctiona... 163 2e-38
gi|77461883|ref|YP_351390.1| dihydroorotase [Pseudomonas fl... 162 3e-38
gi|517425|gb|AAA73440.1| dihydro-orotase 162 3e-38
gi|151569756|gb|EDN35410.1| hypothetical protein FTCG_01164... 162 3e-38
gi|32476302|ref|NP_869296.1| dihydroorotase [Rhodopirellula... 162 4e-38
gi|89889443|ref|ZP_01200954.1| dihydroorotase [Flavobacteri... 162 5e-38
gi|114707123|ref|ZP_01440021.1| dihydroorotase [Fulvimarina... 162 5e-38
gi|106893953|ref|ZP_01361076.1| Dihydroorotase multifunctio... 161 6e-38
gi|149187360|ref|ZP_01865658.1| dihydroorotase [Vibrio shil... 161 7e-38
gi|94311671|ref|YP_584881.1| dihydroorotase, multifunctiona... 161 7e-38
gi|118496639|ref|YP_897689.1| dihydroorotase [Francisella t... 161 7e-38
gi|84360993|ref|ZP_00985678.1| COG0044: Dihydroorotase and ... 161 9e-38
gi|17987564|ref|NP_540198.1| dihydroorotase [Brucella melit... 161 9e-38
gi|148560386|ref|YP_001258652.1| dihydroorotase, multifunct... 161 9e-38
gi|62289628|ref|YP_221421.1| dihydroorotase [Brucella abort... 160 1e-37
gi|146309555|ref|YP_001190020.1| Dihydroorotase [Pseudomona... 160 1e-37
gi|145622224|ref|ZP_01778185.1| dihydropyrimidinase [Petrot... 160 1e-37
gi|23501555|ref|NP_697682.1| dihydroorotase [Brucella suis ... 160 1e-37
gi|90420871|ref|ZP_01228776.1| dihydroorotase [Aurantimonas... 160 1e-37
gi|49474073|ref|YP_032115.1| dihydroorotase [Bartonella qui... 160 1e-37
gi|126648684|ref|ZP_01721168.1| Allantoinase [Algoriphagus ... 160 1e-37
gi|73540415|ref|YP_294935.1| dihydroorotase [Ralstonia eutr... 160 1e-37
gi|134302751|ref|YP_001122719.1| putative dihydroorotase, m... 159 2e-37
gi|56708672|ref|YP_170568.1| dihydroorotase [Francisella tu... 159 2e-37
gi|157121352|gb|EDO65553.1| dihydroorotase [Francisella tul... 159 2e-37
gi|113475820|ref|YP_721881.1| dihydroorotase, multifunction... 159 2e-37
gi|151572889|gb|EDN38543.1| hypothetical protein FTDG_01362... 159 3e-37
gi|119511689|ref|ZP_01630794.1| dihydroorotase [Nodularia s... 159 3e-37
gi|150004795|ref|YP_001299539.1| dihydroorotase [Bacteroide... 159 3e-37
gi|69937389|ref|ZP_00632055.1| Dihydroorotase multifunction... 159 3e-37
gi|149913417|ref|ZP_01901950.1| dihydroorotase, multifuncti... 159 3e-37
gi|13476463|ref|NP_108033.1| dihydroorotase [Mesorhizobium ... 159 3e-37
gi|89255480|ref|YP_512841.1| Dihydroorotase [Francisella tu... 159 4e-37
gi|149275915|ref|ZP_01882060.1| dihydroorotase [Pedobacter ... 159 5e-37
gi|149200960|ref|ZP_01877935.1| dihydroorotase, multifuncti... 158 5e-37
gi|149371961|ref|ZP_01891280.1| dihydroorotase [unidentifie... 158 6e-37
gi|153807962|ref|ZP_01960630.1| hypothetical protein BACCAC... 158 6e-37
gi|16126683|ref|NP_421247.1| aspartate transcarbamoylase, p... 158 8e-37
gi|78043954|ref|YP_359533.1| allantoinase [Carboxydothermus... 157 9e-37
gi|91782037|ref|YP_557243.1| Dihydroorotase multifunctional... 157 9e-37
gi|89900175|ref|YP_522646.1| amidohydrolase [Rhodoferax fer... 157 9e-37
>gi|148324483|gb|EDK89733.1| dihydroorotase [Fusobacterium nucleatum subsp. polymorphum ATCC
10953]
Length = 425
Score = 838 bits (2164), Expect = 0.0, Method: Composition-based stats.
Identities = 425/425 (100%), Positives = 425/425 (100%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR
Sbjct: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG
Sbjct: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
Query: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL
Sbjct: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG
Sbjct: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD
Sbjct: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP
Sbjct: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
Query: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK
Sbjct: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
Query: 421 EEINL 425
EEINL
Sbjct: 421 EEINL 425
>gi|34762310|ref|ZP_00143314.1| Dihydroorotase [Fusobacterium nucleatum subsp. vincentii ATCC
49256]
gi|27888032|gb|EAA25095.1| Dihydroorotase [Fusobacterium nucleatum subsp. vincentii ATCC
49256]
Length = 425
Score = 795 bits (2052), Expect = 0.0, Method: Composition-based stats.
Identities = 397/425 (93%), Positives = 414/425 (97%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
MLLKNCKILKNGKFKKVDILIKDDKIEKISENID+ DENTIDVK++FVTAGFIDAHVHWR
Sbjct: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDIADENTIDVKNKFVTAGFIDAHVHWR 60
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDS+ETLNKQLE+IK DSVIRAIPYG
Sbjct: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSIETLNKQLELIKKDSVIRAIPYG 120
Query: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
AITKEEYGRELSDME IA VFAFTDDGRGVQ+ANVMYEAMLMG+KLNKAIVAHCEDNSL
Sbjct: 121 AITKEEYGRELSDMEAIASDVFAFTDDGRGVQNANVMYEAMLMGAKLNKAIVAHCEDNSL 180
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
IRGGAMHEGKRS ELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG
Sbjct: 181 IRGGAMHEGKRSVELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K+N I+VTCEVTPHHLLSCDEDIKEDNGMWKMNPPLR REDRNALI G+LDGTIDIIATD
Sbjct: 241 KQNGIKVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRSREDRNALIVGILDGTIDIIATD 300
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPHTMEEKIRGIEKSSFGIVGSETAF QLYTKFVKTDIFSLE+LVKLMSENVAKIF+LP
Sbjct: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFAQLYTKFVKTDIFSLELLVKLMSENVAKIFDLP 360
Query: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
YGKLEENSFADIVVIDLEKE+TINP+EFLSKGRNTPYANEK++GI VLTISNGKIAYID+
Sbjct: 361 YGKLEENSFADIVVIDLEKEMTINPKEFLSKGRNTPYANEKISGISVLTISNGKIAYIDE 420
Query: 421 EEINL 425
EEINL
Sbjct: 421 EEINL 425
>gi|19703762|ref|NP_603324.1| dihydroorotase [Fusobacterium nucleatum subsp. nucleatum ATCC
25586]
gi|22001883|sp|Q8RG88|PYRC_FUSNN Dihydroorotase (DHOase)
gi|19713900|gb|AAL94623.1| Dihydroorotase [Fusobacterium nucleatum subsp. nucleatum ATCC
25586]
Length = 425
Score = 792 bits (2045), Expect = 0.0, Method: Composition-based stats.
Identities = 397/425 (93%), Positives = 410/425 (96%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
MLLKNCKILKN KF+KVDILI+D+KIEKISENID+TDEN ID+K+RFVTAGFID HVHWR
Sbjct: 1 MLLKNCKILKNTKFEKVDILIRDNKIEKISENIDITDENIIDIKNRFVTAGFIDVHVHWR 60
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIK DSVIRAIPYG
Sbjct: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKKDSVIRAIPYG 120
Query: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
AITKEEYGRELSDME IA VFAFTDDGRGVQSANVMYEAMLMG+KLNKAIVAHCEDNSL
Sbjct: 121 AITKEEYGRELSDMEAIASNVFAFTDDGRGVQSANVMYEAMLMGAKLNKAIVAHCEDNSL 180
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
IRGGAMHEGKRSAELGIKGIPSICESTQI RD+LLAEAANCHYHVCHISAKESVRAVREG
Sbjct: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIVRDVLLAEAANCHYHVCHISAKESVRAVREG 240
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
KKN I+VTCEVTPHHLLSCDEDIKEDNGMWKMNPPLR REDRNALI G+LDGTIDIIATD
Sbjct: 241 KKNGIKVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRSREDRNALIVGILDGTIDIIATD 300
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPHTMEEKIRGIEKSSFGIVGSETAF QLYTKFVKTDIFSLEMLVKLMSENVAKIF+LP
Sbjct: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFAQLYTKFVKTDIFSLEMLVKLMSENVAKIFDLP 360
Query: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
YGKLEENSFADIVVIDLEKEITINP FLSKG+NTPY NEK+NGIPVLTISNGKIAYIDK
Sbjct: 361 YGKLEENSFADIVVIDLEKEITINPNNFLSKGKNTPYINEKINGIPVLTISNGKIAYIDK 420
Query: 421 EEINL 425
EEINL
Sbjct: 421 EEINL 425
>gi|26554243|ref|NP_758177.1| dihydroorotase [Mycoplasma penetrans HF-2]
gi|26454252|dbj|BAC44581.1| dihydroorotase [Mycoplasma penetrans HF-2]
Length = 426
Score = 501 bits (1291), Expect = e-140, Method: Composition-based stats.
Identities = 249/426 (58%), Positives = 321/426 (75%), Gaps = 1/426 (0%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENID-VTDENTIDVKDRFVTAGFIDAHVHW 59
MLLKNC ILKN K K DILIK+++I KI++ I+ +E ID+K V G ID HVH+
Sbjct: 1 MLLKNCSILKNNKLIKSDILIKNNRIIKIAKKIENKNNEEEIDIKSNLVIPGLIDVHVHF 60
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPGF KET+ T S +AA+GGFTTVMTMPNLNPVP ++E LN QL++IK SVIR IPY
Sbjct: 61 REPGFIHKETIKTGSMSAAKGGFTTVMTMPNLNPVPHNLENLNVQLDLIKRHSVIRCIPY 120
Query: 120 GAITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
G+I+ +E G +LSD+E+++ VF F+DDG+G+Q+ N+MY+AML+ K NK I AHCEDNS
Sbjct: 121 GSISVDENGEQLSDVENLSKYVFGFSDDGKGIQNNNLMYQAMLLAKKHNKPICAHCEDNS 180
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
L G ++EG S +L +KGI + E+ QIARD++LA+A CHYHVCH+S KES+ ++E
Sbjct: 181 LANKGVINEGVASEKLNLKGINPLAETIQIARDLVLAKATKCHYHVCHVSTKESLELIKE 240
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
KK I VTCEVTPHHLLS D+DI DNG WKMNPPLR +D+ ALI V + IDIIAT
Sbjct: 241 AKKKKINVTCEVTPHHLLSIDQDILNDNGKWKMNPPLRSIQDQKALIKAVKNKLIDIIAT 300
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH+ +EK ++FGI+GSE AF+ LYTKFVKT +FSL++LV L ++NVAKIF L
Sbjct: 301 DHAPHSKQEKNCSFNDAAFGIIGSEFAFSLLYTKFVKTKVFSLQLLVDLFTKNVAKIFKL 360
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYG LEEN AD+ V DL K I +E LSK +NTPY N+KV G+ +LTISNGKI Y++
Sbjct: 361 PYGVLEENKIADLAVFDLNKSFEIKEDEILSKSKNTPYLNQKVYGVSLLTISNGKIVYLN 420
Query: 420 KEEINL 425
++E+++
Sbjct: 421 EKELSV 426
>gi|70726714|ref|YP_253628.1| dihydroorotase [Staphylococcus haemolyticus JCSC1435]
gi|68447438|dbj|BAE05022.1| dihydroorotase [Staphylococcus haemolyticus JCSC1435]
Length = 424
Score = 485 bits (1248), Expect = e-135, Method: Composition-based stats.
Identities = 240/419 (57%), Positives = 311/419 (74%), Gaps = 4/419 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENT--IDVKDRFVTAGFIDAHVHW 59
L+KN +IL NG+ K+ ILI I++I+ NI+V DEN ID + FV G ID HVH
Sbjct: 3 LIKNAQILDNGELKQASILIDGQHIKEINNNIEV-DENVEVIDAQGHFVAPGLIDVHVHL 61
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG KET+ T ++AAARGGFTTV MPN PVPDSVE +++ ++I++++ +R +PY
Sbjct: 62 REPGGEHKETIKTGTKAAARGGFTTVCPMPNTRPVPDSVEHMDRLQQLIQDNAQVRVLPY 121
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+IT + G+E D + +A + FAFTDDG GVQ + +MYEAM +K+NKA+VAHCEDN
Sbjct: 122 ASITVRQAGKEHVDFDALAKQGAFAFTDDGVGVQESAMMYEAMQQAAKVNKAVVAHCEDN 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SLI GGAMH+GKRS ELGI GIP+ICE+ QIARD+LLAEAANCHYHVCH+S KESVRA+R
Sbjct: 182 SLIYGGAMHQGKRSEELGIPGIPNICEAVQIARDVLLAEAANCHYHVCHVSTKESVRAIR 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+ K I VT EVTPHHLL ++D+ DN ++KMNPPLR +EDR+AL+ G+LDGTID IA
Sbjct: 242 DAKAAGIHVTAEVTPHHLLLTEDDVPGDNAIFKMNPPLRSKEDRDALLEGLLDGTIDCIA 301
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH EEK + + K+ FGIVGSETAF LYT FVK +SL+ LV ++ A+ F+
Sbjct: 302 TDHAPHAKEEKAQPMTKAPFGIVGSETAFPLLYTHFVKNGDWSLQQLVDYLTIKPAQTFD 361
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
LPYGKLEE FAD+ +I+L++E I E+FLSK NTP+ KV G P+LT+ G++ +
Sbjct: 362 LPYGKLEEGCFADLTIINLDEEREIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKF 420
>gi|73662880|ref|YP_301661.1| dihydroorotase [Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305]
gi|72495395|dbj|BAE18716.1| dihydroorotase [Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305]
Length = 424
Score = 481 bits (1238), Expect = e-134, Method: Composition-based stats.
Identities = 241/411 (58%), Positives = 303/411 (73%), Gaps = 2/411 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDEN-TIDVKDRFVTAGFIDAHVHWR 60
LL N KILKNG+ V ILI+ I+KI+ +IDVT E IDVK +FV+ G +D HVH R
Sbjct: 3 LLTNAKILKNGELTTVSILIEGQHIKKIAPHIDVTLETEVIDVKGQFVSPGLVDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGGFTTV MPN PVPDS E LN+ ++I+ ++ +R +PY
Sbjct: 63 EPGGEHKETIETGTKAAARGGFTTVCPMPNTKPVPDSEENLNRLNQLIEENAQVRVLPYA 122
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + G+E D E +A+ FAFTDDG GVQ A++MYEAM +K+NKA+VAHCEDNS
Sbjct: 123 AITVRQAGKEHVDFETLANNGAFAFTDDGVGVQQASMMYEAMQAAAKVNKAVVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GGAMHEG+RS LGI GIP+ICE+ QIARD+LLAEAA HYHVCH+S KESVR +R+
Sbjct: 183 LIYGGAMHEGQRSEALGIPGIPNICEAVQIARDVLLAEAAGAHYHVCHVSTKESVRTIRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
KK I VT EVTPHHLL ++D+ D+ ++KMNPPLR +EDR AL+ G+LDGTID IAT
Sbjct: 243 AKKAGIHVTAEVTPHHLLLTEDDVPGDDAIYKMNPPLRSKEDREALLEGLLDGTIDCIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH EEK + + K+ FGIVGSETAF LYT FVK ++L+ LV ++ A+ F+L
Sbjct: 303 DHAPHAAEEKNQPMTKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPAQTFDL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTI 410
P+G+LEE AD+ VI+LE+E I E+F SKG NTP+ KV G PVLT+
Sbjct: 363 PFGRLEEGYLADLTVINLEEESEIKAEDFASKGTNTPFIGYKVYGTPVLTM 413
>gi|82750806|ref|YP_416547.1| dihydroorotase [Staphylococcus aureus RF122]
gi|82656337|emb|CAI80754.1| dihydroorotase [Staphylococcus aureus RF122]
Length = 424
Score = 477 bits (1227), Expect = e-133, Method: Composition-based stats.
Identities = 234/418 (55%), Positives = 305/418 (72%), Gaps = 2/418 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWR 60
L+KN K+L+NG+ ++ DILI I++I+ I+ ++ + ID K FV+ GF+D HVH R
Sbjct: 3 LIKNGKVLQNGELQQADILIDGKVIKQIAPTIEPSNGVDIIDAKGHFVSPGFVDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGGFTTV MPN PVPDSVE ++I +++ +R +PY
Sbjct: 63 EPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYA 122
Query: 121 AITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT + G+EL D + + FAFTDDG GVQ+A++MYE M+ +K+NKAIVAHCEDNS
Sbjct: 123 SITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GGAMHEGKRS ELGI GIP+ICES QIARD+LLAEAA CHYHVCH+S KESVR +R+
Sbjct: 183 LIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I VT EVTPHHLL ++DI +N ++KMNPPLR EDR AL+ G+LDGTID IAT
Sbjct: 243 AKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH +EK + +EK+ FGIVGSETAF LYT FVK ++L+ LV ++ + FNL
Sbjct: 303 DHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
YG L+EN +AD+ +IDL+ E I E+FLSK NTP+ KV G P+LT+ G++ +
Sbjct: 363 EYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKF 420
>gi|15924191|ref|NP_371725.1| dihydroorotase [Staphylococcus aureus subsp. aureus Mu50]
gi|15926784|ref|NP_374317.1| dihydroorotase [Staphylococcus aureus subsp. aureus N315]
gi|21282813|ref|NP_645901.1| dihydroorotase [Staphylococcus aureus subsp. aureus MW2]
gi|49486040|ref|YP_043261.1| dihydroorotase [Staphylococcus aureus subsp. aureus MSSA476]
gi|57651770|ref|YP_186076.1| dihydroorotase [Staphylococcus aureus subsp. aureus COL]
gi|87161310|ref|YP_493791.1| dihydroorotase [Staphylococcus aureus subsp. aureus USA300]
gi|88194907|ref|YP_499707.1| dihydroorotase [Staphylococcus aureus subsp. aureus NCTC 8325]
gi|151221324|ref|YP_001332146.1| dihydroorotase multifunctional complex type [Staphylococcus aureus
subsp. aureus str. Newman]
gi|156979522|ref|YP_001441781.1| dihydroorotase [Staphylococcus aureus subsp. aureus Mu3]
gi|54038940|sp|P65906|PYRC_STAAN Dihydroorotase (DHOase)
gi|54038941|sp|P65907|PYRC_STAAW Dihydroorotase (DHOase)
gi|54041760|sp|P65905|PYRC_STAAM Dihydroorotase (DHOase)
gi|56749526|sp|Q6GA12|PYRC_STAAS Dihydroorotase (DHOase)
gi|71153085|sp|Q5HGN1|PYRC_STAAC Dihydroorotase (DHOase)
gi|13701000|dbj|BAB42296.1| dihydroorotase [Staphylococcus aureus subsp. aureus N315]
gi|14246971|dbj|BAB57363.1| dihydroorotase [Staphylococcus aureus subsp. aureus Mu50]
gi|21204251|dbj|BAB94949.1| dihydroorotase [Staphylococcus aureus subsp. aureus MW2]
gi|49244483|emb|CAG42912.1| putative dihydroorotase [Staphylococcus aureus subsp. aureus
MSSA476]
gi|57285956|gb|AAW38050.1| dihydroorotase [Staphylococcus aureus subsp. aureus COL]
gi|87127284|gb|ABD21798.1| dihydroorotase [Staphylococcus aureus subsp. aureus USA300_FPR3757]
gi|87202465|gb|ABD30275.1| dihydroorotase [Staphylococcus aureus subsp. aureus NCTC 8325]
gi|150374124|dbj|BAF67384.1| dihydroorotase multifunctional complex type [Staphylococcus aureus
subsp. aureus str. Newman]
gi|156721657|dbj|BAF78074.1| dihydroorotase [Staphylococcus aureus subsp. aureus Mu3]
Length = 424
Score = 476 bits (1226), Expect = e-133, Method: Composition-based stats.
Identities = 234/418 (55%), Positives = 305/418 (72%), Gaps = 2/418 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWR 60
L+KN K+L+NG+ ++ DILI I++I+ I+ ++ + ID K FV+ GF+D HVH R
Sbjct: 3 LIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGGFTTV MPN PVPDSVE ++I +++ +R +PY
Sbjct: 63 EPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYA 122
Query: 121 AITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT + G+EL D + + FAFTDDG GVQ+A++MYE M+ +K+NKAIVAHCEDNS
Sbjct: 123 SITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GGAMHEGKRS ELGI GIP+ICES QIARD+LLAEAA CHYHVCH+S KESVR +R+
Sbjct: 183 LIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I VT EVTPHHLL ++DI +N ++KMNPPLR EDR AL+ G+LDGTID IAT
Sbjct: 243 AKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH +EK + +EK+ FGIVGSETAF LYT FVK ++L+ LV ++ + FNL
Sbjct: 303 DHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
YG L+EN +AD+ +IDL+ E I E+FLSK NTP+ KV G P+LT+ G++ +
Sbjct: 363 EYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKF 420
>gi|148267692|ref|YP_001246635.1| dihydroorotase, multifunctional complex type [Staphylococcus aureus
subsp. aureus JH9]
gi|150393750|ref|YP_001316425.1| dihydroorotase, multifunctional complex type [Staphylococcus aureus
subsp. aureus JH1]
gi|147740761|gb|ABQ49059.1| dihydroorotase, multifunctional complex type [Staphylococcus aureus
subsp. aureus JH9]
gi|149946202|gb|ABR52138.1| dihydroorotase, multifunctional complex type [Staphylococcus aureus
subsp. aureus JH1]
Length = 425
Score = 476 bits (1226), Expect = e-133, Method: Composition-based stats.
Identities = 234/418 (55%), Positives = 305/418 (72%), Gaps = 2/418 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWR 60
L+KN K+L+NG+ ++ DILI I++I+ I+ ++ + ID K FV+ GF+D HVH R
Sbjct: 4 LIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGGFTTV MPN PVPDSVE ++I +++ +R +PY
Sbjct: 64 EPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYA 123
Query: 121 AITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT + G+EL D + + FAFTDDG GVQ+A++MYE M+ +K+NKAIVAHCEDNS
Sbjct: 124 SITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNS 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GGAMHEGKRS ELGI GIP+ICES QIARD+LLAEAA CHYHVCH+S KESVR +R+
Sbjct: 184 LIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I VT EVTPHHLL ++DI +N ++KMNPPLR EDR AL+ G+LDGTID IAT
Sbjct: 244 AKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH +EK + +EK+ FGIVGSETAF LYT FVK ++L+ LV ++ + FNL
Sbjct: 304 DHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
YG L+EN +AD+ +IDL+ E I E+FLSK NTP+ KV G P+LT+ G++ +
Sbjct: 364 EYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKF 421
>gi|49483364|ref|YP_040588.1| dihydroorotase [Staphylococcus aureus subsp. aureus MRSA252]
gi|56749573|sp|Q6GHN4|PYRC_STAAR Dihydroorotase (DHOase)
gi|49241493|emb|CAG40179.1| putative dihydroorotase [Staphylococcus aureus subsp. aureus
MRSA252]
Length = 424
Score = 476 bits (1226), Expect = e-132, Method: Composition-based stats.
Identities = 234/418 (55%), Positives = 305/418 (72%), Gaps = 2/418 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWR 60
L+KN K+L+NG+ ++ DILI I++I+ I+ ++ + ID K FV+ GF+D HVH R
Sbjct: 3 LIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGIDIIDAKGHFVSPGFVDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGGFTTV MPN PVPDSVE ++I +++ +R +PY
Sbjct: 63 EPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYA 122
Query: 121 AITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT + G+EL D + + FAFTDDG GVQ+A++MYE M+ +K+NKAIVAHCEDNS
Sbjct: 123 SITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GGAMHEGKRS ELGI GIP+ICES QIARD+LLAEAA CHYHVCH+S KESVR +R+
Sbjct: 183 LIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I VT EVTPHHLL ++DI +N ++KMNPPLR EDR AL+ G+LDGTID IAT
Sbjct: 243 AKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH +EK + +EK+ FGIVGSETAF LYT FVK ++L+ LV ++ + FNL
Sbjct: 303 DHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
YG L+EN +AD+ +IDL+ E I E+FLSK NTP+ KV G P+LT+ G++ +
Sbjct: 363 EYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKF 420
>gi|15615101|ref|NP_243404.1| dihydroorotase [Bacillus halodurans C-125]
gi|20139768|sp|Q9K9V7|PYRC_BACHD Dihydroorotase (DHOase)
gi|10175158|dbj|BAB06257.1| dihydroorotase [Bacillus halodurans C-125]
Length = 428
Score = 468 bits (1204), Expect = e-130, Method: Composition-based stats.
Identities = 236/422 (55%), Positives = 294/422 (69%), Gaps = 2/422 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L+KN I+ K G K D+L+ D I I N++ TD + I+ + VT G +D HVH R
Sbjct: 4 LIKNGSIVTKEGTVKTQDVLLHDGVISAIGLNLEETDAHVIEANGKLVTPGLVDLHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAA+GGFTTV MPN PVPDS E ++ I V+R +PY
Sbjct: 64 EPGGEAKETIETGTKAAAKGGFTTVAAMPNTRPVPDSAEQMSWLTGRIDETGVVRVLPYA 123
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + GREL+D + + FAFTDDG GVQSA +M EAM +KL AIVAHCE+N+
Sbjct: 124 AITTRQLGRELTDFAKLKEAGAFAFTDDGVGVQSAAMMLEAMKEAAKLEMAIVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI+ G++HEG S + GI GIPS+CES IARD+LLAEAA HYHVCHIS KESVR VR+
Sbjct: 184 LIQNGSVHEGVFSKKHGIAGIPSVCESVHIARDVLLAEAAGVHYHVCHISTKESVRVVRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ IRVT EVTPHHLL CDEDI + +KMNPPLRG+EDR ALI G+LDGTID IAT
Sbjct: 244 AKRAGIRVTAEVTPHHLLLCDEDIPGLDAHYKMNPPLRGKEDREALIEGLLDGTIDFIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +G+E++ FGIVG ETAF LYT FVK F+L+ LV ++ + A+ F L
Sbjct: 304 DHAPHTEEEKGQGMERAPFGIVGLETAFPLLYTHFVKKGTFTLKQLVDWLTIDPAETFQL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYG+LEE + AD+ +IDLE E I+P F SKGRNTP+A G PV T+ GK+ + +
Sbjct: 364 PYGRLEEGAPADVTIIDLEAERAIDPAHFASKGRNTPFAGWTCQGWPVATLVGGKLVWEE 423
Query: 420 KE 421
KE
Sbjct: 424 KE 425
>gi|27467795|ref|NP_764432.1| dihydroorotase [Staphylococcus epidermidis ATCC 12228]
gi|38258091|sp|Q8CPJ6|PYRC_STAES Dihydroorotase (DHOase)
gi|27315339|gb|AAO04474.1|AE016746_264 dihydroorotase [Staphylococcus epidermidis ATCC 12228]
Length = 425
Score = 464 bits (1193), Expect = e-129, Method: Composition-based stats.
Identities = 237/419 (56%), Positives = 294/419 (70%), Gaps = 3/419 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDEN--TIDVKDRFVTAGFIDAHVHW 59
L+KN KILKNG K +ILI +I++IS I+ + N ID K + GF+D HVH
Sbjct: 3 LIKNGKILKNGILKDTEILIDGKRIKQISSKINASSSNIEVIDAKGNLIAPGFVDVHVHL 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG KET+ + ++AAARGGFTTV MPN PVPD+VE + + + I + +R +PY
Sbjct: 63 REPGGEHKETIESGTKAAARGGFTTVCPMPNTRPVPDTVEHVRELRQRISETAQVRVLPY 122
Query: 120 GAITKEEYGRELSDMEDIA-DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
AITK + G EL D E +A + VFAFTDDG GVQ+A++MY AM K+ K IVAHCEDN
Sbjct: 123 AAITKRQAGTELVDFEKLALEGVFAFTDDGVGVQTASMMYAAMKQAVKVKKPIVAHCEDN 182
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SLI GGAMH+GKRS ELGI GIP+I ES QIARD+LLAEA CHYHVCH+S KESVR +R
Sbjct: 183 SLIYGGAMHKGKRSEELGIPGIPNIAESVQIARDVLLAEATGCHYHVCHVSTKESVRVIR 242
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+ KK I VT EVTPHHLL + D+ D+ +KMNPPLR EDR AL+ G+LDGTID IA
Sbjct: 243 DAKKAGIHVTAEVTPHHLLLTENDVPGDDSNYKMNPPLRSNEDREALLEGLLDGTIDCIA 302
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH EEK + + K+ FGIVGSETAF LYT FV+ +SL+ LV + A IFN
Sbjct: 303 TDHAPHAKEEKAQPMTKAPFGIVGSETAFPLLYTHFVRRGNWSLQQLVDYFTIKPATIFN 362
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L YGKL ++S+AD+ +IDL E I E+FLSK NTP+ EKV G P LT+ G++ +
Sbjct: 363 LNYGKLHKDSYADLTIIDLNTEKEIKSEDFLSKADNTPFIGEKVYGNPTLTMLKGEVVF 421
>gi|57866724|ref|YP_188350.1| dihydroorotase [Staphylococcus epidermidis RP62A]
gi|71153086|sp|Q5HPZ0|PYRC_STAEQ Dihydroorotase (DHOase)
gi|57637382|gb|AAW54170.1| dihydroorotase [Staphylococcus epidermidis RP62A]
Length = 425
Score = 463 bits (1191), Expect = e-128, Method: Composition-based stats.
Identities = 237/419 (56%), Positives = 295/419 (70%), Gaps = 3/419 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDEN--TIDVKDRFVTAGFIDAHVHW 59
L+KN KILKNG K +ILI +I++IS I+ + N ID K + GF+D HVH
Sbjct: 3 LIKNGKILKNGILKDTEILIDGKRIKQISSKINASSSNIEVIDAKGNLIAPGFVDVHVHL 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG KET+ + ++AAARGGFTTV MPN PVPD+VE + + + I + +R +PY
Sbjct: 63 REPGGEHKETIESGTKAAARGGFTTVCPMPNTRPVPDTVEHVRELRQRISETAQVRVLPY 122
Query: 120 GAITKEEYGRELSDMEDIA-DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
AITK + G EL D E +A + VFAFTDDG GVQ+A++MY AM +K+ K IVAHCEDN
Sbjct: 123 AAITKRQAGTELVDFEKLALEGVFAFTDDGVGVQTASMMYAAMKQAAKVKKPIVAHCEDN 182
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SLI GGAMH+GKRS ELGI GIP+I ES QIARD+LLAEA CHYHVCH+S KESVR +R
Sbjct: 183 SLIYGGAMHKGKRSEELGIPGIPNIAESVQIARDVLLAEATGCHYHVCHVSTKESVRVIR 242
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+ KK I VT EVTPHHLL + D+ D+ +KMNPPLR EDR AL+ G+LDGTID IA
Sbjct: 243 DAKKAGIHVTAEVTPHHLLLTENDVPGDDSNYKMNPPLRSNEDREALLEGLLDGTIDCIA 302
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH EEK + + K+ FGIVGSETAF LYT FV+ +SL+ LV + A IFN
Sbjct: 303 TDHAPHAKEEKEQPMTKAPFGIVGSETAFPLLYTHFVRRGNWSLQQLVDYFTIKPATIFN 362
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L YGKL ++S+AD+ +IDL E I E+FLSK NTP+ EKV G P LT+ G++ +
Sbjct: 363 LNYGKLHKDSYADLTIIDLNTEKEIKSEDFLSKADNTPFIGEKVYGNPTLTMLKGEVVF 421
>gi|23098944|ref|NP_692410.1| dihydroorotase [Oceanobacillus iheyensis HTE831]
gi|22777172|dbj|BAC13445.1| dihydroorotase [Oceanobacillus iheyensis HTE831]
Length = 430
Score = 459 bits (1181), Expect = e-127, Method: Composition-based stats.
Identities = 232/423 (54%), Positives = 296/423 (69%), Gaps = 1/423 (0%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+LL ++L + + +KV++LI+D+KI KI+ I EN ID++ + + G ID H+H R
Sbjct: 4 ILLNANRLLPSNELEKVEVLIEDNKIIKIASQIPDKVENYIDIEGKLLLPGLIDVHIHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T + AAARGG+TTV MPN NPVPD E L L I +D+ IR +PY
Sbjct: 64 EPGGEHKETIKTGTMAAARGGYTTVCAMPNTNPVPDHPEALTSLLSKIADDAHIRVLPYA 123
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+ITK G E +D++ + D FAFTDDG G+Q+A+ MY+AM ++ N IVAHCEDNS
Sbjct: 124 SITKSLKGEERTDIQSLIDAGAFAFTDDGVGIQTADQMYQAMKDAARHNTTIVAHCEDNS 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
L+ GG +HEG+ S L + GIPS+ ES QIARD+LLAEA CHYHVCH+S KESVR +R+
Sbjct: 184 LVYGGVLHEGEVSERLSLPGIPSLSESVQIARDVLLAEATGCHYHVCHVSTKESVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
KK I VT EV+PHHLL + DI +DN WKMNPPLR ED+ AL G++DGTID+IAT
Sbjct: 244 AKKAGIHVTAEVSPHHLLLNETDIPDDNADWKMNPPLRSTEDQQALFDGLMDGTIDLIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH EEK G +++ FGIVG ETAF LYT V +L LV+ M+E A F L
Sbjct: 304 DHAPHATEEKAVGFKEAPFGIVGLETAFPLLYTHLVLKGKMTLYQLVERMTEKPAATFQL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYGKLEE+S ADI VIDLEKE TI+ E F SKG+NTP+ N KV GIPVLT+ NG + Y +
Sbjct: 364 PYGKLEEDSVADITVIDLEKEETIHRETFYSKGKNTPFDNWKVKGIPVLTMVNGVVVYEE 423
Query: 420 KEE 422
++
Sbjct: 424 AKQ 426
>gi|16801017|ref|NP_471285.1| dihydroorotase [Listeria innocua Clip11262]
gi|21542203|sp|Q92AH1|PYRC_LISIN Dihydroorotase (DHOase)
gi|16414452|emb|CAC97181.1| pyrC [Listeria innocua]
Length = 426
Score = 457 bits (1175), Expect = e-127, Method: Composition-based stats.
Identities = 230/422 (54%), Positives = 299/422 (70%), Gaps = 2/422 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+LKN ++L ++G+ + D+LI++ K+ I+++I+VT D + + GFID HVH R
Sbjct: 3 VLKNGQVLNESGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGG+TT+ +MPN PVPDS E +N IK + +R +PY
Sbjct: 63 EPGGEHKETILTGTKAAARGGYTTICSMPNTKPVPDSKEVMNSLQAKIKETAEVRVLPYA 122
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT EL D E + + FAFTDDG GVQ A MYEAM + L+ AIVAHCEDNS
Sbjct: 123 SITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GG +H+G + + G+KGIP+I ES QIARD+LLAEAA CHYHVCHIS KESVR VR+
Sbjct: 183 LIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ IRVT EV+PHHL+ +EDI ++G WKMNPPLR +EDR AL+ G+LDGTID IAT
Sbjct: 243 AKRAGIRVTAEVSPHHLILDEEDIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH EEK +E+++FGIVG ETAF LYT FVKT+ ++L+ L+ M+ A+ F L
Sbjct: 303 DHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYGKLEE + ADIVV+DLEKE TI+P F SKG+NTP+ E G PV T + G++ Y +
Sbjct: 363 PYGKLEEGAVADIVVLDLEKEATIDPATFYSKGKNTPFVGETCIGWPVATFAEGELVYNE 422
Query: 420 KE 421
E
Sbjct: 423 GE 424
>gi|16803877|ref|NP_465362.1| dihydroorotase [Listeria monocytogenes EGD-e]
gi|47096558|ref|ZP_00234148.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes str. 1/2a F6854]
gi|153175068|ref|ZP_01930463.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes FSL N3-165]
gi|153179873|ref|ZP_01933046.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes F6900]
gi|153183327|ref|ZP_01934187.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes J0161]
gi|21542200|sp|Q8Y663|PYRC_LISMO Dihydroorotase (DHOase)
gi|16411291|emb|CAC99915.1| pyrC [Listeria monocytogenes]
gi|47015090|gb|EAL06033.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes str. 1/2a F6854]
gi|126943618|gb|EBA21335.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes J0161]
gi|133729521|gb|EBA31219.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes FSL N3-165]
gi|133732517|gb|EBA34215.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes F6900]
Length = 426
Score = 455 bits (1170), Expect = e-126, Method: Composition-based stats.
Identities = 230/422 (54%), Positives = 296/422 (70%), Gaps = 2/422 (0%)
Query: 2 LLKNCKILK-NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+LKN ++L +GK + D+LI++ K+ I+++I+VT D + +T GFID HVH R
Sbjct: 3 VLKNGQVLNASGKLESKDVLIQNGKVNLIADSIEVTSGEEFDATGKLITPGFIDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGG+TT+ +MPN PVPDS E + IK + +R +PY
Sbjct: 63 EPGGEHKETILTGTKAAARGGYTTICSMPNTKPVPDSKEVMESIQAKIKETAKVRVLPYA 122
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT EL D E + + FAFTDDG GVQ A MYEAM + L+ AIVAHCEDNS
Sbjct: 123 SITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GG +H+G + + G+KGIP+I ES QIARD+LLAEAA CHYHVCHIS KESVR VR+
Sbjct: 183 LIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ IRVT EV+PHHL+ +E I ++G WKMNPPLR +EDR AL+ G+LDGTID IAT
Sbjct: 243 AKRAGIRVTAEVSPHHLILDEEAIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH EEK +E+++FGIVG ETAF LYT FVKT+ ++L+ L+ M+ A+ F L
Sbjct: 303 DHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYGKLEE S ADIVV+DLEKE I+P+ F SKG+NTP+ E G PV T + G + Y +
Sbjct: 363 PYGKLEEGSVADIVVLDLEKEANIDPDTFYSKGKNTPFVGETCIGWPVATFAEGTLVYNE 422
Query: 420 KE 421
E
Sbjct: 423 GE 424
>gi|149182325|ref|ZP_01860803.1| dihydroorotase [Bacillus sp. SG-1]
gi|148849944|gb|EDL64116.1| dihydroorotase [Bacillus sp. SG-1]
Length = 434
Score = 454 bits (1168), Expect = e-126, Method: Composition-based stats.
Identities = 233/423 (55%), Positives = 288/423 (68%), Gaps = 2/423 (0%)
Query: 2 LLKNCKILK-NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
++KN K L+ +G D+ I + I +I EN+ + D + + GF+D HVH R
Sbjct: 12 IIKNAKWLEESGTISIKDVKIVEKYIAEIGENLSEENAEIFDAEGLLLLPGFVDLHVHLR 71
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KKET+ T ++AAARGGFTT+ MPN PVPD VETL E I +R +PY
Sbjct: 72 EPGGEKKETIETGTKAAARGGFTTIAAMPNTRPVPDDVETLQWLNERITETGKVRVLPYA 131
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT+ + G+ L+D + + FAFTDDG GVQ A MYEAM + +N IVAHCEDNS
Sbjct: 132 SITERQLGKNLTDFPALKESGAFAFTDDGVGVQEAGKMYEAMKAAAAVNMVIVAHCEDNS 191
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GGA+HEGK S E G KGIPSICES QIARD+LLAEAA+CHYHVCHIS KESVR VR+
Sbjct: 192 LIYGGAVHEGKFSKENGFKGIPSICESVQIARDVLLAEAADCHYHVCHISTKESVRVVRD 251
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
KK I+VT EVTPHHLL ++DI D+ +KMNPPLR REDR+ALI G+LDGTID IAT
Sbjct: 252 AKKAGIKVTAEVTPHHLLLTEDDIPGDDANYKMNPPLRSREDRDALIEGLLDGTIDFIAT 311
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK GI + FGIVG ETAF LYT FV+ +IF+L LV M++ ++ F L
Sbjct: 312 DHAPHTAEEKSEGIALAPFGIVGLETAFPLLYTNFVEKEIFTLNQLVDWMTKKPSQTFKL 371
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYG LE S ADI ++DL + INPE FLSKGRNTP+ G P T + G + + +
Sbjct: 372 PYGTLEIGSLADITLVDLTETREINPETFLSKGRNTPFGGWVCKGWPKATFAEGTLTWKE 431
Query: 420 KEE 422
E+
Sbjct: 432 GEQ 434
>gi|89208472|ref|ZP_01186977.1| Dihydroorotase multifunctional complex type [Bacillus
weihenstephanensis KBAB4]
gi|89153595|gb|EAR73659.1| Dihydroorotase multifunctional complex type [Bacillus
weihenstephanensis KBAB4]
Length = 428
Score = 452 bits (1164), Expect = e-125, Method: Composition-based stats.
Identities = 225/418 (53%), Positives = 288/418 (68%), Gaps = 2/418 (0%)
Query: 2 LLKNCKILK-NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L KN + + G D+L++D KI K++ENI + IDV + + G +D HVH R
Sbjct: 4 LFKNGRYMNAEGTIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T + AAA+GGFTT+ MPN PVPD E + + IK + + +PYG
Sbjct: 64 EPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCKEHMEDLQKRIKEKAHVNVLPYG 123
Query: 121 AITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + G E++D E + + FAFTDDG GVQ A++M AM SKLN A+VAHCE+N+
Sbjct: 124 AITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRASKLNMAVVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G +HEGK S + G+ GIPS+CES IARDILLAEAANCHYHVCH+S K SVR +R+
Sbjct: 184 LINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAANCHYHVCHVSTKGSVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I+VT EVTPHHL+ C++DI + +KMNPPLRG+ED ALI G+LDGTID+IAT
Sbjct: 244 AKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +GIE++ FGI G ETAF LYT VK I +LE L++ ++E A F L
Sbjct: 304 DHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+L E ADI +IDLE+E I+P FLSKG+NTP+A K G PV+TI GKIA+
Sbjct: 364 EAGRLTEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAW 421
>gi|46908069|ref|YP_014458.1| dihydroorotase [Listeria monocytogenes str. 4b F2365]
gi|47093074|ref|ZP_00230852.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes str. 4b H7858]
gi|153167680|ref|ZP_01927784.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes FSL N1-017]
gi|153202834|ref|ZP_01944272.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes HPB2262]
gi|67460855|sp|Q71YH9|PYRC_LISMF Dihydroorotase (DHOase)
gi|46881339|gb|AAT04635.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes str. 4b F2365]
gi|47018575|gb|EAL09330.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes str. 4b H7858]
gi|133726779|gb|EBA28477.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes FSL N1-017]
gi|133734904|gb|EBA36602.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes HPB2262]
Length = 426
Score = 452 bits (1162), Expect = e-125, Method: Composition-based stats.
Identities = 229/422 (54%), Positives = 294/422 (69%), Gaps = 2/422 (0%)
Query: 2 LLKNCKILK-NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+LKN ++L +G+ + D+LI++ K+ I+++I+VT D + + GFID HVH R
Sbjct: 3 VLKNGQVLNASGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGG+TT+ +MPN PVPDS E + IK + +R +PY
Sbjct: 63 EPGGEHKETILTGTQAAARGGYTTICSMPNTKPVPDSKEVMESLQAKIKETAKVRVLPYA 122
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT EL D E + + FAFTDDG GVQ A MYEAM + L+ AIVAHCEDNS
Sbjct: 123 SITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GG +H+G + + G+KGIP+I ES QIARD+LLAEAA CHYHVCHIS KESVR VR+
Sbjct: 183 LIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ IRVT EV+PHHL+ +E I ++G WKMNPPLR +EDR AL+ G+LDGTID IAT
Sbjct: 243 AKRAGIRVTAEVSPHHLILDEEAIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH EEK +E+++FGIVG ETAF LYT FVKT+ ++L+ L+ M+ A+ F L
Sbjct: 303 DHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYGKLEE S ADIVV+DLEKE I+P F SKG+NTP+ E G PV T S G + Y +
Sbjct: 363 PYGKLEEGSVADIVVLDLEKEANIDPATFYSKGKNTPFVGETCIGWPVATFSEGTLVYNE 422
Query: 420 KE 421
E
Sbjct: 423 GE 424
>gi|30263891|ref|NP_846268.1| dihydroorotase [Bacillus anthracis str. Ames]
gi|47529320|ref|YP_020669.1| dihydroorotase [Bacillus anthracis str. 'Ames Ancestor']
gi|49186738|ref|YP_029990.1| dihydroorotase [Bacillus anthracis str. Sterne]
gi|65321216|ref|ZP_00394175.1| COG0044: Dihydroorotase and related cyclic amidohydrolases
[Bacillus anthracis str. A2012]
gi|30258535|gb|AAP27754.1| dihydroorotase [Bacillus anthracis str. Ames]
gi|47504468|gb|AAT33144.1| dihydroorotase [Bacillus anthracis str. 'Ames Ancestor']
gi|49180665|gb|AAT56041.1| dihydroorotase [Bacillus anthracis str. Sterne]
Length = 428
Score = 452 bits (1162), Expect = e-125, Method: Composition-based stats.
Identities = 224/418 (53%), Positives = 290/418 (69%), Gaps = 2/418 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L KN + + + GK D+L++D KI K++ENI + IDV + + G +D HVH R
Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T + AAA+GGFTT+ MPN PVPD E + IK + + +PYG
Sbjct: 64 EPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYG 123
Query: 121 AITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + G E++D E + + FAFTDDG GVQ A++M AM +KLN A+VAHCE+N+
Sbjct: 124 AITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G +HEGK S + G+ GIPS+CES IARDILLAEAA+CHYHVCH+S K SVR +R+
Sbjct: 184 LINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I+VT EVTPHHL+ C++DI + +KMNPPLRG+ED ALI G+LDGTID+IAT
Sbjct: 244 AKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHEALIEGLLDGTIDMIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +GIE++ FGI G ETAF LYT VK I +LE L++ ++E A F L
Sbjct: 304 DHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+L+E ADI +IDLE+E I+P FLSKG+NTP+A K G PV+TI GKIA+
Sbjct: 364 EAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAW 421
>gi|47569516|ref|ZP_00240196.1| dihydroorotase [Bacillus cereus G9241]
gi|52141600|ref|YP_085229.1| dihydroorotase [Bacillus cereus E33L]
gi|118479109|ref|YP_896260.1| dihydroorotase [Bacillus thuringiensis str. Al Hakam]
gi|47553845|gb|EAL12216.1| dihydroorotase [Bacillus cereus G9241]
gi|51975069|gb|AAU16619.1| dihydroorotase [Bacillus cereus E33L]
gi|118418334|gb|ABK86753.1| dihydroorotase [Bacillus thuringiensis str. Al Hakam]
Length = 428
Score = 452 bits (1162), Expect = e-125, Method: Composition-based stats.
Identities = 224/418 (53%), Positives = 290/418 (69%), Gaps = 2/418 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L KN + + + GK D+L++D KI K++ENI + IDV + + G +D HVH R
Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T + AAA+GGFTT+ MPN PVPD E + IK + + +PYG
Sbjct: 64 EPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYG 123
Query: 121 AITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + G E++D E + + FAFTDDG GVQ A++M AM +KLN A+VAHCE+N+
Sbjct: 124 AITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G +HEGK S + G+ GIPS+CES IARDILLAEAA+CHYHVCH+S K SVR +R+
Sbjct: 184 LINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I+VT EVTPHHL+ C++DI + +KMNPPLRG+ED ALI G+LDGTID+IAT
Sbjct: 244 AKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +GIE++ FGI G ETAF LYT VK I +LE L++ ++E A F L
Sbjct: 304 DHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+L+E ADI +IDLE+E I+P FLSKG+NTP+A K G PV+TI GKIA+
Sbjct: 364 EAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAW 421
>gi|42782981|ref|NP_980228.1| dihydroorotase [Bacillus cereus ATCC 10987]
gi|42738908|gb|AAS42836.1| dihydroorotase [Bacillus cereus ATCC 10987]
Length = 428
Score = 452 bits (1162), Expect = e-125, Method: Composition-based stats.
Identities = 224/418 (53%), Positives = 290/418 (69%), Gaps = 2/418 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L KN + + + GK D+L++D KI K++ENI + IDV + + G +D HVH R
Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T + AAA+GGFTT+ MPN PVPD E + IK + + +PYG
Sbjct: 64 EPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYG 123
Query: 121 AITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + G E++D E + + FAFTDDG GVQ A++M AM +KLN A+VAHCE+N+
Sbjct: 124 AITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G +HEGK S + G+ GIPS+CES IARDILLAEAA+CHYHVCH+S K SVR +R+
Sbjct: 184 LINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I+VT EVTPHHL+ C++DI + +KMNPPLRG+ED ALI G+LDGTID+IAT
Sbjct: 244 AKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +GIE++ FGI G ETAF LYT VK I +LE L++ ++E A F L
Sbjct: 304 DHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+L+E ADI +IDLE+E I+P FLSKG+NTP+A K G PV+TI GKIA+
Sbjct: 364 EAGRLKEGRAADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAW 421
>gi|153196345|ref|ZP_01940715.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes 10403S]
gi|127633806|gb|EBA23198.1| dihydroorotase, multifunctional complex type [Listeria
monocytogenes 10403S]
Length = 426
Score = 451 bits (1160), Expect = e-125, Method: Composition-based stats.
Identities = 228/422 (54%), Positives = 295/422 (69%), Gaps = 2/422 (0%)
Query: 2 LLKNCKILK-NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+LKN ++L +G+ + D+LI++ K+ I+++I+VT D + + GFID HVH R
Sbjct: 3 VLKNGQVLNASGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGG+TT+ +MPN PVPDS E + IK + +R +PY
Sbjct: 63 EPGGEHKETILTGTQAAARGGYTTICSMPNTKPVPDSKEVMENLQAKIKETAEVRVLPYA 122
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT EL D E + + FAFTDDG GVQ A MYEAM + L+ AIVAHCEDNS
Sbjct: 123 SITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GG +H+G + + G+KGIP+I ES QIARD+LLAEAA CHYHVCHIS KESVR VR+
Sbjct: 183 LIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ IRVT EV+PHHL+ +E I ++G WKMNPPLR +EDR AL+ G+LDGTID IAT
Sbjct: 243 AKRAGIRVTAEVSPHHLILDEEAIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH EEK +E+++FGIVG ETAF LYT FVKT+ ++L+ L+ M+ A+ F L
Sbjct: 303 DHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYGKLEE S ADIVV+DLEKE I+P+ F SKG+NTP+ E G PV T + G + Y +
Sbjct: 363 PYGKLEEGSVADIVVLDLEKEANIDPDTFYSKGKNTPFVGETCIGWPVATFAEGTLVYNE 422
Query: 420 KE 421
E
Sbjct: 423 GE 424
>gi|152976249|ref|YP_001375766.1| dihydroorotase, multifunctional complex type [Bacillus cereus
subsp. cytotoxis NVH 391-98]
gi|152025001|gb|ABS22771.1| dihydroorotase, multifunctional complex type [Bacillus cereus
subsp. cytotoxis NVH 391-98]
Length = 428
Score = 451 bits (1160), Expect = e-125, Method: Composition-based stats.
Identities = 223/418 (53%), Positives = 291/418 (69%), Gaps = 2/418 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L KN + L + G D+L++D KI KI++NI + IDV + + G +D HVH R
Sbjct: 4 LFKNGRYLNEEGTIVATDLLVQDGKIAKIAKNISAENAEVIDVNGKLIAPGLVDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T + AAA+GGFTT+ MPN PVPDS E + + I+ + + +PYG
Sbjct: 64 EPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDSKEHMEDLQKRIQEKAHVNVLPYG 123
Query: 121 AITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + G E++D E + + FAFTDDG GVQ A++M AM +KLN A+VAHCE+N+
Sbjct: 124 AITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G +HEGK S + G+ GIPS+CES IARDILLAEAA+CHYHVCH+S K SVR +R+
Sbjct: 184 LINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I+VT EVTPHHL+ C++DI + +KMNPPLRGRED+ ALI G+LDGTIDIIAT
Sbjct: 244 AKRAGIKVTAEVTPHHLVLCEDDIPSVDPNFKMNPPLRGREDQEALIEGLLDGTIDIIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +GIE++ FGI G ETAF LYT VK I +LE L++ ++E A F L
Sbjct: 304 DHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+L+E ADI ++DLE+E I+P FLSKG+NTP+A K G PV+T+ GKI +
Sbjct: 364 ETGRLKEGRAADITILDLEQEEKIDPTTFLSKGKNTPFAGWKCQGWPVMTLVGGKIVW 421
>gi|116873272|ref|YP_850053.1| dihydroorotase [Listeria welshimeri serovar 6b str. SLCC5334]
gi|116742150|emb|CAK21274.1| pyrC [Listeria welshimeri serovar 6b str. SLCC5334]
Length = 426
Score = 451 bits (1159), Expect = e-125, Method: Composition-based stats.
Identities = 227/422 (53%), Positives = 295/422 (69%), Gaps = 2/422 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+LKN +IL ++G+ + D+LI++ K+ I+++I+VT D + + GFID HVH R
Sbjct: 3 VLKNGQILNESGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T ++AAARGG+TT+ +MPN PVPDS E + + IK + +R +PY
Sbjct: 63 EPGGEHKETILTGTKAAARGGYTTICSMPNTKPVPDSKEVMERLQAKIKETAEVRVLPYA 122
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT EL D E + + FAFTDDG GVQ A MYEAM + L+ AIVAHCEDNS
Sbjct: 123 SITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GG +H+G + G+KGIP+I ES QIARD+LLAEAA CHYHVCHIS KESVR VR+
Sbjct: 183 LIYGGVVHDGIFAEREGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRD 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ IRVT EV+PHHL+ +E I ++G WKMNPPLR + DR AL+ G+LDGTID IAT
Sbjct: 243 AKRAGIRVTAEVSPHHLILDEEAIPGNDGQWKMNPPLRSKADRAALLEGLLDGTIDFIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH EEK +E+++FGIVG ETAF LYT FV+T+ ++L+ L+ M+ A+ F L
Sbjct: 303 DHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVQTNEWTLKQLIDWMTVKPAECFKL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYGKLEE + ADIVV+DLEKE TI+P+ F SKG+NTP+ E G PV T G + Y +
Sbjct: 363 PYGKLEEGTTADIVVLDLEKEATIDPDTFYSKGKNTPFVGETCIGWPVATFVEGTLVYKE 422
Query: 420 KE 421
E
Sbjct: 423 GE 424
>gi|49478433|ref|YP_037950.1| dihydroorotase [Bacillus thuringiensis serovar konkukian str.
97-27]
gi|49329989|gb|AAT60635.1| dihydroorotase [Bacillus thuringiensis serovar konkukian str.
97-27]
Length = 428
Score = 450 bits (1157), Expect = e-125, Method: Composition-based stats.
Identities = 223/418 (53%), Positives = 289/418 (69%), Gaps = 2/418 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L KN + + + GK D+L++D KI K++ENI + IDV + + G +D HVH R
Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T + AAA+GGFTT+ MPN PVPD E + IK + + +PYG
Sbjct: 64 EPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYG 123
Query: 121 AITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + G E++D E + + FAFTDDG GVQ A++M AM +KLN A+VAHCE+N+
Sbjct: 124 AITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G +HEGK S + G+ GIPS+CES IARDILLAEAA+CHYHVCH+S K SVR +R+
Sbjct: 184 LINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I+VT EVTPHHL+ C++DI + +KMNPPLRG+ED ALI G+LDGTID+IAT
Sbjct: 244 AKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +GIE++ FGI G ETAF LYT VK I +LE L++ ++E A F L
Sbjct: 304 DHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+L+E ADI +IDLE+E I+P FLSKG+NTP+ K G PV+TI GKIA+
Sbjct: 364 EAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFVGWKCQGWPVMTIVGGKIAW 421
>gi|30021977|ref|NP_833608.1| dihydroorotase [Bacillus cereus ATCC 14579]
gi|29897533|gb|AAP10809.1| Dihydroorotase [Bacillus cereus ATCC 14579]
Length = 428
Score = 448 bits (1153), Expect = e-124, Method: Composition-based stats.
Identities = 221/418 (52%), Positives = 291/418 (69%), Gaps = 2/418 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L KN + + + GK D+L++D KI K++ENI + IDV + + G +D HVH R
Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ T + AAA+GGFTT+ MPN PVPD E + + I+ + + +PYG
Sbjct: 64 EPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQKRIEEKAHVNVLPYG 123
Query: 121 AITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT + G E++D E + + FAFTDDG GVQ A++M AM +KL+ A+VAHCE+N+
Sbjct: 124 AITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLDMAVVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G +HEGK S + G+ GIPS+CES IARDILLAEAA+CHYHVCH+S K SVR +R+
Sbjct: 184 LINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I+VT EVTPHHL+ C++DI + +KMNPPLRG+ED ALI G+LDGTID+IAT
Sbjct: 244 AKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +GIE++ FGI G ETAF LYT VK + +LE L++ ++E A F L
Sbjct: 304 DHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGVITLEQLIQFLTEKPADTFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+L+E ADI +IDLE+E I+P FLSKG+NTP+A K G PV+TI GKIA+
Sbjct: 364 EAGRLKEGRAADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAW 421
>gi|154685966|ref|YP_001421127.1| PyrC [Bacillus amyloliquefaciens FZB42]
gi|154351817|gb|ABS73896.1| PyrC [Bacillus amyloliquefaciens FZB42]
Length = 428
Score = 444 bits (1141), Expect = e-123, Method: Composition-based stats.
Identities = 227/410 (55%), Positives = 283/410 (69%), Gaps = 15/410 (3%)
Query: 23 DDKIEKISENIDVTDE--------------NTIDVKDRFVTAGFIDAHVHWREPGFSKKE 68
+++ EK++++I VT E ID + FV+ G +D HVH+REPG KKE
Sbjct: 12 NEQGEKVAQDIRVTGEFISETGLLTAKDGETVIDAEGLFVSPGLVDLHVHFREPGGEKKE 71
Query: 69 TVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYG 128
T+ T S+AAARGGFTTV MPN PVPD+ E + IK S +R +PY +IT + G
Sbjct: 72 TIETGSKAAARGGFTTVAAMPNTRPVPDTKEQMEWLQNRIKETSSVRVLPYASITIRQTG 131
Query: 129 RELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
E++D + + + FAFTDDG GVQ+A +MYEAM + +NKAIVAHCEDNSLI GG++H
Sbjct: 132 EEMTDFKALHEAGAFAFTDDGVGVQTAGMMYEAMKRAASMNKAIVAHCEDNSLIYGGSVH 191
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
EG S G+ GIPSICE+ IARD+LLAEAA CHYHVCHIS KESVRAVR+ KK IRV
Sbjct: 192 EGSFSKANGLNGIPSICEAVHIARDVLLAEAAGCHYHVCHISTKESVRAVRDAKKAGIRV 251
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
T EV+PHHLL CDEDI + +KMNPPLR +EDR ALI G+LDGTID IATDHAPHT E
Sbjct: 252 TAEVSPHHLLLCDEDIPGLDTNFKMNPPLRSKEDREALIEGLLDGTIDFIATDHAPHTEE 311
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEEN 367
EK ++ + FGIVG ETAF LYT FVK ++L+ LV M+ + F LPYG L
Sbjct: 312 EKNTDMKLAPFGIVGLETAFPLLYTHFVKNGEWTLKQLVDFMTVKPCEAFALPYGTLAPG 371
Query: 368 SFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+ ADI +IDLEKE I+ + FLSKG+NTP+ K G PV T++ GK+AY
Sbjct: 372 APADITLIDLEKEAAIDKDTFLSKGKNTPFNKMKCFGWPVATMAAGKLAY 421
>gi|124520886|ref|ZP_01695958.1| dihydroorotase, multifunctional complex type [Bacillus coagulans
36D1]
gi|124497255|gb|EAY44820.1| dihydroorotase, multifunctional complex type [Bacillus coagulans
36D1]
Length = 428
Score = 441 bits (1134), Expect = e-122, Method: Composition-based stats.
Identities = 225/418 (53%), Positives = 276/418 (66%), Gaps = 2/418 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L+K +L + G+ K DI IKD KI + + E D V GF+D HVH R
Sbjct: 4 LIKGGMVLDEKGESVKRDIRIKDGKIAETGSELKEAGEQVYDATGLTVLPGFVDLHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGF +KET+ T + AAA+GGFTTV MPN PV D L E I D+V+R +PY
Sbjct: 64 EPGFEQKETIRTGTMAAAKGGFTTVAAMPNTKPVTDRPARLLSLKEKISRDAVVRVLPYA 123
Query: 121 AITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT +E G EL D + A FAFTDDG GVQ A M AM L A+VAHCEDNS
Sbjct: 124 AITLDEKGGELVDFAGLKAAGAFAFTDDGVGVQEAGQMLAAMEQAKALGMAVVAHCEDNS 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LIRGG +H+G +A G+KGIPS+CES QIARD+LLAE CHYHVCHIS KESVR VR+
Sbjct: 184 LIRGGCVHDGSFAAAHGLKGIPSVCESVQIARDVLLAEHTGCHYHVCHISTKESVRVVRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I VT EVTPHHLL ++DI + WKMNPPLR + DR+ALI G+LDGTID IAT
Sbjct: 244 AKRAGIPVTAEVTPHHLLLSEDDIPGPDANWKMNPPLRSKRDRDALIEGLLDGTIDFIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK +GIE++ FGI G ETAF LYT FV+T IF+L+ LV M+ A +F L
Sbjct: 304 DHAPHTAEEKAKGIEQAPFGITGFETAFPLLYTHFVETGIFTLKQLVDWMTIKPASVFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
PYG L+ + ADI ++L +E TI+P+ FLSKG+NTP+ G P T +GK+ +
Sbjct: 364 PYGTLKTGAPADITAVNLAEEKTIDPDRFLSKGKNTPFLGCVCKGFPQATWGSGKLVW 421
>gi|56419685|ref|YP_147003.1| dihydroorotase [Geobacillus kaustophilus HTA426]
gi|56379527|dbj|BAD75435.1| dihydroorotase [Geobacillus kaustophilus HTA426]
Length = 428
Score = 440 bits (1132), Expect = e-122, Method: Composition-based stats.
Identities = 219/411 (53%), Positives = 278/411 (67%), Gaps = 3/411 (0%)
Query: 10 KNGKFKKVDILIKDDKIEKI--SENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKK 67
K+G+ + I I+ I I + ++ +E+ IDV R + G ID HVH REPG K
Sbjct: 13 KDGELMRTHIKIEHGTIAAILYEQPLEANEEDVIDVGGRLIVPGLIDLHVHLREPGGEAK 72
Query: 68 ETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEY 127
ET+ T + AAA+GGFTTV MPN NP PD E + I+ + + +PY AIT +
Sbjct: 73 ETIETGTLAAAKGGFTTVAAMPNTNPAPDRKEQMEWLQARIRETARVNVLPYAAITIGQK 132
Query: 128 GRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAM 186
G EL+D + + FAFTDDG GVQSA +M+EAM + L+ AIVAHCED++L GGA+
Sbjct: 133 GEELTDFAALKEAGAFAFTDDGVGVQSAGMMFEAMKQAAALDMAIVAHCEDDTLTNGGAV 192
Query: 187 HEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIR 246
H+G+ + G++GIPS+CE+ IARD+LLAEAA CHYHVCHIS KESVR VR+ K+ IR
Sbjct: 193 HDGEFARRYGLRGIPSVCEAVHIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIR 252
Query: 247 VTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTM 306
VT EVTPHHLL CDEDI + +KMNPPLR REDR+ALI G+LDGTID IATDHAPHT
Sbjct: 253 VTAEVTPHHLLLCDEDIPGLDANYKMNPPLRSREDRDALIEGLLDGTIDFIATDHAPHTA 312
Query: 307 EEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEE 366
EK +GIE + FGIVG ETAF LYT FVKT +F+L+ LV ++ A+ F L G+L
Sbjct: 313 AEKAKGIEAAPFGIVGLETAFPLLYTHFVKTGVFTLKQLVDWLTIKPAQCFGLKAGRLAV 372
Query: 367 NSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+ ADI VIDLE E I+PE F SKG+NTP+A G PV+T G + +
Sbjct: 373 GAPADIAVIDLETEEAIDPETFASKGKNTPFAGWVCQGWPVMTFVGGTLVW 423
>gi|56964100|ref|YP_175831.1| dihydroorotase [Bacillus clausii KSM-K16]
gi|56910343|dbj|BAD64870.1| dihydroorotase [Bacillus clausii KSM-K16]
Length = 427
Score = 439 bits (1129), Expect = e-121, Method: Composition-based stats.
Identities = 220/415 (53%), Positives = 284/415 (68%), Gaps = 4/415 (0%)
Query: 10 KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKET 69
+NG+ D+ IKD KI + + D+ + D ++ GF+D HVH REPG KKET
Sbjct: 13 ENGEQVAKDVYIKDGKIVEHVADGDIRQQ--FDATGLLISPGFVDVHVHLREPGGEKKET 70
Query: 70 VYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR 129
+ T ++AAARGGFTTV MPN PVPD+ E L+ I +V+R +PY +IT + G+
Sbjct: 71 IETGTKAAARGGFTTVAAMPNTRPVPDNAEQLDLLQARISETAVVRVLPYASITTRQLGQ 130
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
EL+D + + + FAFTDDG G+Q A +M AM + LN A+VAHCEDNSLI GGA+HE
Sbjct: 131 ELTDFKALKEAGAFAFTDDGVGIQEAGMMLSAMKEAAALNMAVVAHCEDNSLINGGAVHE 190
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G + G+ GIPS+CE+ IARD+LLAEAA HYHVCH+S KESVR +R+ KK IRVT
Sbjct: 191 GHYAKAHGLNGIPSVCEAVHIARDVLLAEAAGAHYHVCHVSTKESVRTIRDAKKAGIRVT 250
Query: 249 CEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEE 308
EVTPHHLL C++DI + +KMNPPLR +EDR+AL+AG+LDGTID IATDHAPHT EE
Sbjct: 251 AEVTPHHLLLCEDDIIGKDPNFKMNPPLRAKEDRDALVAGLLDGTIDFIATDHAPHTAEE 310
Query: 309 KIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENS 368
K +E++ FGIVG ETAF LYT FVK F+L+ L+ ++ A+ FNLPYG L+ +
Sbjct: 311 KSASLERAPFGIVGLETAFPLLYTHFVKPGTFTLKQLIDWLTVKPAQTFNLPYGTLQVGA 370
Query: 369 FADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKEEI 423
AD+ +IDL+ TI+P FLSKG+NTP+A GIP T+ GK Y KE I
Sbjct: 371 AADLTLIDLKANETIDPSMFLSKGKNTPFAGWDCAGIPQATMVAGKTVY-KKERI 424
>gi|1172784|sp|P46538|PYRC_BACCL Dihydroorotase (DHOase)
gi|312441|emb|CAA51737.1| dihydroorotase [Bacillus caldolyticus]
Length = 427
Score = 438 bits (1127), Expect = e-121, Method: Composition-based stats.
Identities = 220/410 (53%), Positives = 276/410 (67%), Gaps = 2/410 (0%)
Query: 10 KNGKFKKVDILIKDDKIEKI-SENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKE 68
K+G+ + I I+ I I E +E+ IDV R + G ID HVH REPG KE
Sbjct: 13 KDGELMRTHIKIEHGTIAAILYEQPLEANEDVIDVGGRLIVPGLIDLHVHLREPGGEAKE 72
Query: 69 TVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYG 128
T+ T + AAA+GGFTTV MPN NP PD E + I+ + + +PY AIT + G
Sbjct: 73 TIETGTLAAAKGGFTTVAAMPNTNPAPDRKEQMEWLQARIRETARVNVLPYAAITIGQKG 132
Query: 129 RELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
EL+D + + FAFTDDG GVQSA +M+EAM + L+ AIVAHCED++L GGA+H
Sbjct: 133 EELTDFAALKEAGAFAFTDDGVGVQSAGMMFEAMKQAAALDMAIVAHCEDDTLTNGGAVH 192
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
+G+ + G++GIPS+CE+ IARD+LLAEAA CHYHVCHIS KESVR VR+ K+ IRV
Sbjct: 193 DGEFARRYGLRGIPSVCEAVHIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRV 252
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
T EVTPHHLL CDEDI + +KMNPPLR REDR+ALI G+LDGTID IATDHAPHT
Sbjct: 253 TAEVTPHHLLLCDEDIPGLDANYKMNPPLRSREDRDALIEGLLDGTIDFIATDHAPHTAA 312
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEEN 367
EK +GIE + FGIVG ETAF LYT FVKT +F+L+ LV ++ A+ F L G+L
Sbjct: 313 EKAKGIEAAPFGIVGLETAFPLLYTHFVKTGVFTLKQLVDWLTIKPAQCFGLKAGRLAVG 372
Query: 368 SFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+ ADI VIDLE E I+PE F SKG+NTP+A G PV+T G + +
Sbjct: 373 APADIAVIDLETEEAIDPETFASKGKNTPFAGWVCQGWPVMTFVGGTLVW 422
>gi|52080152|ref|YP_078943.1| dihydroorotase [Bacillus licheniformis ATCC 14580]
gi|52785529|ref|YP_091358.1| PyrC [Bacillus licheniformis ATCC 14580]
gi|52003363|gb|AAU23305.1| dihydroorotase [Bacillus licheniformis ATCC 14580]
gi|52348031|gb|AAU40665.1| PyrC [Bacillus licheniformis DSM 13]
Length = 428
Score = 436 bits (1121), Expect = e-120, Method: Composition-based stats.
Identities = 223/418 (53%), Positives = 284/418 (67%), Gaps = 2/418 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L+KN +L + G+ + DI ++ D I +I + E ID FV+ G +D HVH+R
Sbjct: 4 LIKNGFMLDEKGEKVQRDIRVEGDAISEIGSLEAASGETVIDADGLFVSPGLVDLHVHFR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KKET+ T ++AAARGGFTTV MPN PVPD+ E + + I + +R +PY
Sbjct: 64 EPGGEKKETIETGAKAAARGGFTTVAAMPNTRPVPDTKEQMEWLVNRIDETASVRVLPYA 123
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT + GRE++D E + D FAFTDDG GVQ+A +MYEAM + +NKAIVAHCEDNS
Sbjct: 124 SITIRQTGREMTDFEGLKDAGAFAFTDDGVGVQTAGMMYEAMKKAASINKAIVAHCEDNS 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GG++H+G+ + G+ GIPS+CE+ IARD+LLAEAA CHYHVCHIS KESVR VR+
Sbjct: 184 LIYGGSVHDGEFAKANGLNGIPSVCEAVHIARDVLLAEAAGCHYHVCHISTKESVRVVRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
KK IRVT EVTPHHLL D DI + +KMNPPLR EDR AL+ G+ DGTID IAT
Sbjct: 244 AKKAGIRVTAEVTPHHLLLSDSDIPGLDTNYKMNPPLRSPEDREALLEGLRDGTIDFIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK + + + FGIVG ETAF LYT FVKT ++L+ L M+ + F L
Sbjct: 304 DHAPHTEEEKQQTMSLAPFGIVGLETAFPLLYTHFVKTGKWTLKQLHDYMTVKPCEAFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
PYGKLE ADI +IDLE+E I+ FLSKG+NTP+ G P +T++ GK+ Y
Sbjct: 364 PYGKLEAGRSADITLIDLEREEKIDKSTFLSKGKNTPFDGISCFGWPAMTMAKGKLVY 421
>gi|89098723|ref|ZP_01171605.1| dihydroorotase [Bacillus sp. NRRL B-14911]
gi|89086685|gb|EAR65804.1| dihydroorotase [Bacillus sp. NRRL B-14911]
Length = 428
Score = 435 bits (1118), Expect = e-120, Method: Composition-based stats.
Identities = 223/425 (52%), Positives = 285/425 (67%), Gaps = 3/425 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L+KN ++L +NG+ + DILI+ KI KI + TD ID G +D HVH R
Sbjct: 4 LIKNGRLLTENGELVQKDILIEGGKIAKIGVEFEGTDAEVIDAGGLLAVPGLVDLHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KKET+ T + AAARGGFTT+ MPN PVPD+VE L I + +R +PY
Sbjct: 64 EPGGEKKETIETGTLAAARGGFTTIAPMPNTRPVPDTVEQLEWLNRRIAETAHVRVLPYA 123
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT + G EL+D E + FAFTDDG GVQSA +M AM + ++ +VAHCE+N+
Sbjct: 124 SITVRQLGSELTDFEGLKQAGAFAFTDDGVGVQSAGMMLSAMKKAAAVSMPVVAHCEENT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G++HEG+ S + I GIPS+CES IARD+LLAEAA CHYHVCHIS KESVR VR+
Sbjct: 184 LINKGSVHEGEFSRKHAINGIPSVCESVHIARDVLLAEAAGCHYHVCHISTKESVRVVRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I+VT EVTPHHLL C++DI + +KMNPPLR DR ALI G+LDGTID IAT
Sbjct: 244 SKRAGIKVTAEVTPHHLLLCEDDIPGLDANFKMNPPLRSASDREALIEGLLDGTIDFIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK G+E + FGI G ETAF LYT V +L+ LV M+ ++ F L
Sbjct: 304 DHAPHTSEEKEEGMELAPFGITGLETAFPLLYTHLVLKGTLTLKQLVDFMTIKPSEAFGL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYGKLEE S AD+V+++L+ I+P+EF+SKG+NTP++ G PVLTI+ GK +
Sbjct: 364 PYGKLEEGSPADLVLVNLDHGQNIDPQEFVSKGKNTPFSGWNCKGWPVLTIAGGKTVWA- 422
Query: 420 KEEIN 424
KE +N
Sbjct: 423 KESVN 427
>gi|126649701|ref|ZP_01721937.1| dihydroorotase [Bacillus sp. B14905]
gi|126593420|gb|EAZ87365.1| dihydroorotase [Bacillus sp. B14905]
Length = 425
Score = 433 bits (1113), Expect = e-119, Method: Composition-based stats.
Identities = 219/422 (51%), Positives = 291/422 (68%), Gaps = 2/422 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+N ++L + G+ + V+I + + I I +++ V I+ K V GF+D H H R
Sbjct: 4 VLQNVQMLNEQGELQTVNIAMAEGIITAIGQDVTVVGAEVIEGKGFIVAPGFVDVHTHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGF KET+ T S +AA+GGFTT+ MPN PVPDSV + +IK +VIR +PYG
Sbjct: 64 EPGFEHKETIATGSASAAKGGFTTICAMPNTKPVPDSVANMQLINGLIKESAVIRVLPYG 123
Query: 121 AITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
++TK+ G +++E++ A+ AF+DDG G+Q A+ MYE M ++ + +VAHCEDNS
Sbjct: 124 SLTKDISGEVRTNVEELKANGAVAFSDDGVGIQLASTMYEQMKDAAQHDMVVVAHCEDNS 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI G MHEGKR+ EL + GIPSICES QIARD+LLAEAA YHVCH+S KESVRAVR+
Sbjct: 184 LIYDGVMHEGKRNKELDLPGIPSICESVQIARDVLLAEAAGARYHVCHVSTKESVRAVRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K IRVT EV PHHLL + DI D+ WKMNPPLRG +D+++L A + DGTID IAT
Sbjct: 244 AKAAGIRVTAEVCPHHLLLEEMDIPSDDANWKMNPPLRGADDKDSLHAALHDGTIDCIAT 303
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT+EEK G+ + FGIVG ETAF LYT+FV+T ++L+ L+ MS A+IF+L
Sbjct: 304 DHAPHTVEEKCCGMVGAPFGIVGFETAFPLLYTQFVETGKWTLKQLIDWMSVKAAEIFDL 363
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
PYG L + AD+++ID++KE TI+ E F+SKGRNTP+ G PVLTI G I Y +
Sbjct: 364 PYGTLAVGASADMILIDIQKEQTIDAEGFVSKGRNTPFNGWVAKGWPVLTIFEGNIVYQE 423
Query: 420 KE 421
E
Sbjct: 424 AE 425
>gi|138894677|ref|YP_001125130.1| Dihydroorotase [Geobacillus thermodenitrificans NG80-2]
gi|134266190|gb|ABO66385.1| Dihydroorotase [Geobacillus thermodenitrificans NG80-2]
Length = 428
Score = 432 bits (1111), Expect = e-119, Method: Composition-based stats.
Identities = 220/421 (52%), Positives = 276/421 (65%), Gaps = 4/421 (0%)
Query: 1 MLLKN-CKILKNGKFKKVDILIKDDKIEKISEN--IDVTDENTIDVKDRFVTAGFIDAHV 57
M LKN +NG+ + I I+ I I + E+ IDV + + G ID HV
Sbjct: 3 MWLKNGMSFNENGQLVRTHIKIEHGNIAAIHHEQLFEANGEDVIDVGGKLIAPGLIDVHV 62
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H REPG KET+ T + AAA+GGFTTV MPN NPVPD E + I+ + +R +
Sbjct: 63 HLREPGGEAKETIETGTLAAAKGGFTTVAAMPNTNPVPDRKEQMEWLARRIQETAHVRVL 122
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
PY +IT + G EL+D + + FAFTDDG GVQSA +M+EAM + L+ AIVAHCE
Sbjct: 123 PYASITLGQKGEELTDFAALKEAGAFAFTDDGVGVQSAGMMFEAMKRAAALDMAIVAHCE 182
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D++L GGA+H+G + GI GIPS+CE+ IARD+LLAEA CHYHVCHIS KESVR
Sbjct: 183 DDTLKNGGAVHDGDFARRYGIAGIPSVCEAVHIARDVLLAEATGCHYHVCHISTKESVRV 242
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
VR+ K+ I VT EVTPHHLL CDEDI + +KMNPPLR R DR ALI G+LDGTID
Sbjct: 243 VRDAKRAGICVTAEVTPHHLLLCDEDIPRLDANYKMNPPLRSRADREALIEGLLDGTIDF 302
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPHT EK +G+E + FGIVG ETAF LYT FVK ++F+L+ LV ++ A+
Sbjct: 303 IATDHAPHTAAEKAKGMEAAPFGIVGLETAFPLLYTHFVKKNVFTLKQLVDWLTIKPAQC 362
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
F L G+LE + ADI VIDLE E I+PE F SKG NTP+A + G PV+T G +
Sbjct: 363 FGLQTGRLEVGAPADITVIDLETEEPIDPETFASKGNNTPFAGWRCQGWPVMTFVGGTLV 422
Query: 417 Y 417
+
Sbjct: 423 W 423
>gi|69247602|ref|ZP_00604413.1| Dihydroorotase multifunctional complex type [Enterococcus faecium
DO]
gi|68194770|gb|EAN09248.1| Dihydroorotase multifunctional complex type [Enterococcus faecium
DO]
Length = 426
Score = 429 bits (1103), Expect = e-118, Method: Composition-based stats.
Identities = 219/419 (52%), Positives = 283/419 (67%), Gaps = 3/419 (0%)
Query: 2 LLKNCKI-LKNGKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHVHW 59
L+KN +I + +I I+D +I+ I + + D K + +T G +D HVH
Sbjct: 4 LIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEVFDAKGQLITPGLVDVHVHL 63
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPGF+ KET+ +R+AARGGFTTV MPNLNPVPD+ E L + +II+ D+V++ + Y
Sbjct: 64 REPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTAEKLRQVYDIIRKDAVVKVLQY 123
Query: 120 GAITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
IT+ +L D E I + FAFT+DG GVQ+A MY AM +K NKA+VAH ED
Sbjct: 124 APITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAGTMYLAMKEAAKNNKALVAHTEDE 183
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL+ GG MH GK++ ELG+ GI S+ ES+QIARD+LLAEA HYHVCH+S KESVR +R
Sbjct: 184 SLLFGGVMHAGKKAEELGLPGILSVTESSQIARDLLLAEATGVHYHVCHVSTKESVRVIR 243
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+ KK I VT EV+PHHL+ DEDI ED G WKMNPPLRGREDR ALI G+LDGTID IA
Sbjct: 244 DAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWKMNPPLRGREDREALIEGLLDGTIDCIA 303
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH +EEK + KS FGIVGSETAF +YT FV+T F+LE ++ ++ A+IF
Sbjct: 304 TDHAPHGLEEKSQSFMKSPFGIVGSETAFQLIYTHFVETGRFTLEQVINWLAVKPAEIFG 363
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L G L + AD+ V D+ + TI+ E+FLSKG NTP+ KV G +T NGK+ +
Sbjct: 364 LNAGTLTVGAPADVAVFDITQTCTIDKEDFLSKGENTPFIGWKVKGETQMTFVNGKLVW 422
>gi|90961173|ref|YP_535089.1| Dihydroorotase [Lactobacillus salivarius subsp. salivarius UCC118]
gi|90820367|gb|ABD99006.1| Dihydroorotase [Lactobacillus salivarius subsp. salivarius UCC118]
Length = 429
Score = 419 bits (1078), Expect = e-115, Method: Composition-based stats.
Identities = 220/426 (51%), Positives = 290/426 (68%), Gaps = 5/426 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENI-DVTDEN--TIDVKDRFVTAGFIDAHVH 58
L+KN + + G+ + D+LI+D KI+ I +N+ DV EN ID ++ V G +D HVH
Sbjct: 4 LIKNGNLYQAGRIYQADVLIEDGKIKAIGKNLSDVVKENLVEIDATNKLVAPGLVDVHVH 63
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+R+PGF+ KET++T S AAA GG+TTV MPNL+PVPD+ E + K + D V++
Sbjct: 64 YRDPGFTYKETIHTGSLAAAHGGYTTVCAMPNLDPVPDTPELVEKMCSRNQEDGVVKVKQ 123
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
YG+IT EL D + FAF++DG GVQ+A MY+AM + LN AIVAH ED
Sbjct: 124 YGSITHGLKSEELVDFVGMKKAGAFAFSNDGSGVQTAGTMYQAMKSAAALNMAIVAHVED 183
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
NSL+ GG M+ GKR+ ELG+ GI I ES+QIARD+LLA+ HYHVCH+S KESV V
Sbjct: 184 NSLLFGGVMNAGKRADELGLPGILGISESSQIARDLLLAKETGVHYHVCHVSTKESVELV 243
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K++ I VTCEV+PHHLL D DI ++ +KMNPPLRG EDR ALI +LDGTID+I
Sbjct: 244 RLAKQHKINVTCEVSPHHLLLADVDIPGNDPYYKMNPPLRGVEDRQALIDSLLDGTIDMI 303
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH+++EK + ++SFGI GSETAF LYTKFVKT IF+LE L++ MS N A+ F
Sbjct: 304 ATDHAPHSIDEKTGDMREASFGITGSETAFAMLYTKFVKTGIFTLEQLLQWMSINPAEKF 363
Query: 358 NLP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G+L AD+ + DL KE I E++LSKG NTP+ EKV G VLT+ +G+
Sbjct: 364 GMEDAGELLPGKSADLAIFDLNKEYVIKEEDYLSKGINTPFTGEKVYGQTVLTMVDGQKV 423
Query: 417 YIDKEE 422
Y +E+
Sbjct: 424 YQREEK 429
>gi|29376270|ref|NP_815424.1| dihydroorotase [Enterococcus faecalis V583]
gi|29343733|gb|AAO81494.1| dihydroorotase [Enterococcus faecalis V583]
Length = 427
Score = 404 bits (1039), Expect = e-111, Method: Composition-based stats.
Identities = 208/424 (49%), Positives = 279/424 (65%), Gaps = 3/424 (0%)
Query: 2 LLKNCKILKN-GKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHVHW 59
L+KN KI+K + + + +++ I I E+ D D E D + +T G +D HVH+
Sbjct: 4 LIKNGKIIKKENQLIEAALWLENGVIHAIGESFDEADFEQVFDANGQLITPGLVDVHVHF 63
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPGF+ KET+ T S+AAARGGFTTV MPNLNPVPD+ E L++ ++I+ D+V++ + Y
Sbjct: 64 REPGFTYKETIKTGSKAAARGGFTTVCAMPNLNPVPDTAEKLSEVYDLIQKDAVVKVLQY 123
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
IT+E L++ + + + FAFT+DG GVQ+A MY AM + LN A+VAH ED
Sbjct: 124 APITEELRSEVLTNQKALKEAGAFAFTNDGVGVQTAGTMYLAMKEAAALNMALVAHTEDE 183
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL+ GG MHEG+ S +LG+ GI S E++QIARDI LA+ HYHVCH+S +ESVR +R
Sbjct: 184 SLLFGGVMHEGEVSKKLGLPGILSATEASQIARDITLAKETGVHYHVCHVSTEESVRVIR 243
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+ KK I VT EV+PHHL+ DEDI D G WKMNPPLRG DR ALI G+LDGTID IA
Sbjct: 244 DAKKAGIHVTAEVSPHHLILVDEDIPGDEGFWKMNPPLRGLADRQALIDGLLDGTIDCIA 303
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH +EEK + + FGIVGSETAF +YT FV+T IF+LE ++ M+ A+IF
Sbjct: 304 TDHAPHGLEEKQQSFLNAPFGIVGSETAFQLIYTNFVETGIFTLEQVIDWMAVKPAEIFG 363
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYI 418
L G L + ADI V DL I+ E F S NTP+ V G ++T +G +A+
Sbjct: 364 LNAGTLTIGAPADIAVFDLATAAPIDAEAFESMAVNTPFTGWTVKGKTLMTFVDGALAWS 423
Query: 419 DKEE 422
++ +
Sbjct: 424 EEAQ 427
>gi|68055452|ref|ZP_00539597.1| Dihydroorotase multifunctional complex type [Exiguobacterium
sibiricum 255-15]
gi|68007958|gb|EAM87197.1| Dihydroorotase multifunctional complex type [Exiguobacterium
sibiricum 255-15]
Length = 423
Score = 400 bits (1028), Expect = e-110, Method: Composition-based stats.
Identities = 211/408 (51%), Positives = 276/408 (67%), Gaps = 3/408 (0%)
Query: 10 KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKET 69
KNG+ +K I ++D + TD+ ID V GF+D HVH REPG KET
Sbjct: 12 KNGQLQKSSIRMEDGIFTDLDATPLETDQ-VIDATGYTVAPGFVDVHVHLREPGGEHKET 70
Query: 70 VYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR 129
+ T + AAA GGFTT+ MPN PVPD ETL+ + I+ + +R PY AI+K + G+
Sbjct: 71 IATGTAAAAAGGFTTICPMPNTRPVPDDRETLDALFKKIEETASVRVFPYAAISKNQLGQ 130
Query: 130 ELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEG 189
EL E + D FAFTDDG GVQSA VM EAM + ++K+I+AHCED+SL + G +HEG
Sbjct: 131 ELVAFEQLTD-AFAFTDDGVGVQSAAVMREAMTRAAAVHKSIIAHCEDDSL-KAGCVHEG 188
Query: 190 KRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTC 249
SA G++GIPS+ ES IARD+L+AEA CHYHVCH+S KESVR +R+ K+ IRVT
Sbjct: 189 AYSAREGLQGIPSLAESIHIARDVLIAEATGCHYHVCHVSTKESVRVIRDAKRAGIRVTA 248
Query: 250 EVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEK 309
EVTPHHL+ ++DI + +KMNPPLR DR AL+AG+ DGTID IATDHAPH EEK
Sbjct: 249 EVTPHHLVLTEDDIIGRDPNFKMNPPLRSEADRQALLAGLQDGTIDCIATDHAPHAAEEK 308
Query: 310 IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSF 369
GIE++ FGI G ETAF LYTK V+ IF+L L MS N A +F+LP+G++E +
Sbjct: 309 AIGIERAPFGITGFETAFPLLYTKLVEPGIFTLNQLFDWMSRNPADLFDLPFGRIEVGAP 368
Query: 370 ADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
AD+V++DLE + P++FLSKG+NTP+A + G PVLT+ G+I +
Sbjct: 369 ADLVLLDLETVRAVQPDQFLSKGKNTPFAGASLTGYPVLTLVGGEIVF 416
>gi|16078614|ref|NP_389433.1| dihydroorotase [Bacillus subtilis subsp. subtilis str. 168]
gi|131715|sp|P25995|PYRC_BACSU Dihydroorotase (DHOase)
gi|143388|gb|AAA21268.1| dihydroorotase [Bacillus subtilis]
gi|2633923|emb|CAB13424.1| dihydroorotase [Bacillus subtilis subsp. subtilis str. 168]
Length = 428
Score = 400 bits (1027), Expect = e-109, Method: Composition-based stats.
Identities = 216/420 (51%), Positives = 275/420 (65%), Gaps = 6/420 (1%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHVHW 59
L+KN IL +NG+ + DI + + I I + +D TD E ID K V+ GF+D HVH+
Sbjct: 4 LIKNGWILNENGEKTQADIRVTGETITAIGK-LDATDNETVIDAKGLLVSPGFVDLHVHF 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG KKET+ T ++AA RGG+TTV MPN PVPD+ E + IK S +R +PY
Sbjct: 63 REPGGEKKETIETGAKAAGRGGYTTVAAMPNTRPVPDTKEQMEWVQNRIKETSCVRVLPY 122
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+IT + G E+++ E + + FAFTDDG G+Q+A +MYEAM + ++KAIVAHCEDN
Sbjct: 123 ASITIRQIGDEMTNFEALKEAGAFAFTDDGVGIQTAGMMYEAMKRAAAIDKAIVAHCEDN 182
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SLI GG++HEG S G+ GIPS+CES IARD+LL ANCHYHVCHIS KESVR VR
Sbjct: 183 SLIYGGSVHEGTFSKANGLNGIPSVCESVHIARDVLLL-GANCHYHVCHISTKESVRVVR 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+ KK IRVT EV+PHHLL CDEDI + +KMNPPLR EDR ALI G+LDGTID IA
Sbjct: 242 DAKKAGIRVTAEVSPHHLLLCDEDIPGLDTNYKMNPPLRSPEDRAALIEGLLDGTIDFIA 301
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAF-TQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
TDHAPHT EEK ++ + F + L+T K + + + M+ + F
Sbjct: 302 TDHAPHTEEEKNTEMKLAPFRNCRLRNSIPASLHTLCQKWQLVTEAADLTYMTIKPCEAF 361
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
LPYG L+ ADI +IDLEKE I+ E FLSKG+NTP+ G PV TI+ GK+AY
Sbjct: 362 GLPYGTLQTGQAADITLIDLEKEAVIDKETFLSKGKNTPFNGISCTGWPVATIAAGKLAY 421
>gi|1346930|sp|P48795|PYRC_LACLE Dihydroorotase (DHOase)
gi|1085058|emb|CAA55633.1| dihydroorotase [Lactobacillus leichmannii]
Length = 427
Score = 384 bits (987), Expect = e-105, Method: Composition-based stats.
Identities = 199/421 (47%), Positives = 279/421 (66%), Gaps = 1/421 (0%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+LLKN + + G+F K D+LI KI+ I ++ D+K + + G +D H H+R
Sbjct: 3 ILLKNGLVYQEGEFIKEDVLISGSKIQAIGLDLPEEGAEVYDLKGKLLAPGLVDIHEHYR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGF+ KET+ T S AA+RGGFTTV TMPN++P+PD +ET KQ+ + + +S + YG
Sbjct: 63 EPGFTYKETIKTGSEAASRGGFTTVCTMPNVDPIPDDLETFEKQVALNEANSCVHLKQYG 122
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AIT++ ++ DM + + FAF++DG G+Q A MYEAM +K+ AI H +D+S
Sbjct: 123 AITEDLTSDKVVDMAALKEAGAFAFSNDGHGIQQAGTMYEAMQEAAKVGLAICEHIQDDS 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
L G M+ GK++ ELG+ GI + ES Q+ARD++LA+A HYH CH+S KESV +R
Sbjct: 183 LYHHGVMNAGKKAEELGLPGILGVSESAQLARDLVLAQATGVHYHACHVSTKESVELIRI 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K+ I VT E TPHHLL +E+I +NG +KMNPPLR +ED+ ALI G+LDGTID+IAT
Sbjct: 243 AKEYGINVTAEATPHHLLLSEEEIDGNNGYYKMNPPLRSKEDQFALIEGMLDGTIDLIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH+ EEK + K++FGI+G+ETAF LYTKFVK+ L +L+ LMS AK+F L
Sbjct: 303 DHAPHSREEKAGDMRKAAFGIIGNETAFACLYTKFVKSGQMDLSLLLDLMSYQPAKLFGL 362
Query: 360 PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
G L AD+ V DL+ ++ E++LSKG NTP+ ++V G+ LT +GK+ Y
Sbjct: 363 DAGVLAPGKEADLAVFDLDHAEKLSEEDYLSKGVNTPFTGQEVYGMTALTFVSGKLVYKS 422
Query: 420 K 420
K
Sbjct: 423 K 423
>gi|104774743|ref|YP_619723.1| Dihydroorotase [Lactobacillus delbrueckii subsp. bulgaricus ATCC
11842]
gi|103423824|emb|CAI98849.1| Dihydroorotase [Lactobacillus delbrueckii subsp. bulgaricus ATCC
11842]
gi|111610236|gb|ABH11614.1| dihydroorotase [Lactobacillus helveticus CNRZ32]
Length = 425
Score = 382 bits (981), Expect = e-104, Method: Composition-based stats.
Identities = 192/419 (45%), Positives = 272/419 (64%), Gaps = 5/419 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
++KN + +NG+ D+LI+D KI+ I D+T + ID + V+ G +D HVH+R+
Sbjct: 4 VIKNGTVYQNGRLIHADVLIEDQKIKAIG--TDLTGDKVIDATGKLVSPGLVDVHVHYRD 61
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG + KE + T S+AAA GGFTTV MPN+ PVPD+ + + K ++ K ++ YG
Sbjct: 62 PGQTYKEDIETGSKAAAHGGFTTVGAMPNVTPVPDTPDLMKKMVQENKQKGIVHIFQYGP 121
Query: 122 ITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
ITK E EL D + FA ++DG GVQ+A MY AM K + + AH +D+SL
Sbjct: 122 ITKNETTDELPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQEAKKNDLIVAAHAQDDSL 181
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
G ++EG+++ EL + + + E+TQIARD+LLAE HYH+CH+S K SV VR
Sbjct: 182 FNHGIVNEGEKAKELNLPPVTELAETTQIARDLLLAEKTGVHYHICHVSTKTSVELVRMA 241
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K I VTCE PHHLL ++DI +DNG +KMNPPLR +ED+ AL+ G+LDGTID+IATD
Sbjct: 242 KACGINVTCEAAPHHLLLTEDDIPKDNGYYKMNPPLRSKEDQAALLVGLLDGTIDLIATD 301
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTD-IFSLEMLVKLMSENVAKIFNL 359
HAPH +EK G++ ++FGI GSETAF+ LYTKFVK D +F+LE L+ +S+ AK+F L
Sbjct: 302 HAPHAKQEKQGGMQNAAFGITGSETAFSTLYTKFVKEDKVFTLEQLLSWLSDQPAKVFGL 361
Query: 360 -PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G LE AD+ + DLE E + + + SKG NTP+ +K+ G V+T+ +G++ Y
Sbjct: 362 KKAGVLEPGCPADVAIFDLEHETELKEKNYQSKGINTPFTGQKIYGATVMTMVDGEVVY 420
>gi|116514878|ref|YP_813784.1| Dihydroorotase [Lactobacillus delbrueckii subsp. bulgaricus ATCC
BAA-365]
gi|116094193|gb|ABJ59346.1| Dihydroorotase [Lactobacillus delbrueckii subsp. bulgaricus ATCC
BAA-365]
Length = 425
Score = 380 bits (977), Expect = e-104, Method: Composition-based stats.
Identities = 192/419 (45%), Positives = 272/419 (64%), Gaps = 5/419 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
++KN + +NG+ D+LI+D KI+ I D+T + ID + V+ G +D HVH+R+
Sbjct: 4 VIKNGTVYQNGRLIHADVLIEDQKIKAIG--TDLTGDKVIDATGKLVSPGLVDVHVHYRD 61
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG + KE + T S+AAA GGFTTV MPN+ PVPD+ + + K ++ K ++ YG
Sbjct: 62 PGQTYKEDIETGSKAAAHGGFTTVGAMPNVTPVPDTPDLMKKMVQENKQKGIVHIFQYGP 121
Query: 122 ITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
ITK E EL D + FA ++DG GVQ+A MY AM K + + AH +D+SL
Sbjct: 122 ITKNETTDELPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQEAKKNDLIVAAHAQDDSL 181
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
G ++EG+++ EL + + + E+TQIARD+LLAE HYH+CH+S K SV VR
Sbjct: 182 FNHGIVNEGEKAKELNLPPVTELAETTQIARDLLLAEKTGVHYHICHVSTKTSVELVRIA 241
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K I VTCE PHHLL ++DI +DNG +KMNPPLR +ED+ AL+ G+LDGTID+IATD
Sbjct: 242 KACGINVTCEAAPHHLLLTEDDIPKDNGYYKMNPPLRSKEDQVALLVGLLDGTIDLIATD 301
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTD-IFSLEMLVKLMSENVAKIFNL 359
HAPH +EK G++ ++FGI GSETAF+ LYTKFVK D +F+LE L+ +S+ AK+F L
Sbjct: 302 HAPHAKQEKQGGMQNAAFGITGSETAFSTLYTKFVKEDKVFTLEQLLSWLSDQPAKVFGL 361
Query: 360 -PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G LE AD+ + DLE E + + + SKG NTP+ +K+ G V+T+ +G++ Y
Sbjct: 362 KKAGVLEPGCPADVAIFDLEHETELKEKNYQSKGINTPFTGQKIYGATVMTMVDGEVVY 420
>gi|116618309|ref|YP_818680.1| Dihydroorotase [Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293]
gi|116097156|gb|ABJ62307.1| Dihydroorotase [Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293]
Length = 425
Score = 377 bits (967), Expect = e-102, Method: Composition-based stats.
Identities = 197/420 (46%), Positives = 273/420 (65%), Gaps = 2/420 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
L+KN KIL N + DILI I+KIS +++ D K F++ G +D HVH+RE
Sbjct: 3 LIKNAKILWNNQLVLRDILIDQGIIQKISNHLESKAATVFDAKGAFLSTGLVDVHVHFRE 62
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PGF KET+ + S+AAARGGFTTV+ MPNLNPVPD+ E + Q+ K + VI YGA
Sbjct: 63 PGFEYKETINSGSKAAARGGFTTVIAMPNLNPVPDNEEKITNQIARNKQNGVIHIEQYGA 122
Query: 122 ITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
I+ ++++++ + A AFT+DG+GVQ+AN M +AM+ + +NK + AH ED++L
Sbjct: 123 ISNNLTSTQVTNIKGMSAAGAKAFTNDGKGVQTANTMLQAMVAAASVNKPLAAHLEDDTL 182
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
+ G M+EGK S +L + GI + ES+Q+ARD++LA+AA HYHV HIS KESV VR
Sbjct: 183 VHDGVMNEGKASTKLELPGITGLAESSQLARDLVLAKAAGVHYHVAHISTKESVELVRIA 242
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K + VT EV+PHHLL +EDI DN M+KMNPPLR + DR A+IAG+LDGTID++ATD
Sbjct: 243 KHEGVHVTAEVSPHHLLLSEEDINSDNAMFKMNPPLRTQRDREAVIAGLLDGTIDMVATD 302
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPH EEK + ++ FGI G ET+F LYT VK + +LE L++ M F+L
Sbjct: 303 HAPHGKEEKQKSFREAPFGITGIETSFQLLYTYLVKNGVMTLETLLERMVTAPVSAFHLQ 362
Query: 361 Y-GKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
+EE + AD+ + DL+ I+ E F S G+N+P+ KV G + T +G+I Y D
Sbjct: 363 APTSIEEGARADLALFDLDNNYEIDTESFESMGKNSPFIGWKVYGKTLATWVDGEIVYKD 422
>gi|58337652|ref|YP_194237.1| dihydroorotase [Lactobacillus acidophilus NCFM]
gi|58254969|gb|AAV43206.1| dihydroorotase [Lactobacillus acidophilus NCFM]
Length = 425
Score = 376 bits (965), Expect = e-102, Method: Composition-based stats.
Identities = 194/419 (46%), Positives = 269/419 (64%), Gaps = 5/419 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
++KN + +NG+ D+LI+D KI+ I N+ T + D + V G +D HVH+RE
Sbjct: 4 VIKNGTVYQNGRLIHADVLIEDQKIKVIGTNL--TGDKEFDATGKLVAPGLVDVHVHYRE 61
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG + KE + T S AAARGGFTTV MPN+ PVP++ E + K ++ + ++ YG
Sbjct: 62 PGQTYKEDIRTGSEAAARGGFTTVGAMPNVTPVPNTPELMEKMVKKNQEKGIVHIFQYGP 121
Query: 122 ITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
IT +E + D + FA ++DG GVQ+A MY AM N I H +D+SL
Sbjct: 122 ITNDETTDIIPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQKAKANNLIIATHAQDDSL 181
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
G ++EGK++ EL + + + E+TQIARD+LLA+ HYH+CH+S K SV VR
Sbjct: 182 FNHGIVNEGKKAEELNLPPVTELAETTQIARDLLLAQKTGVHYHICHVSTKTSVELVRMA 241
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K I VTCEV PHH+L D+DI +DNG +KMNPPLR +ED+ AL+ G+LDGTID+IATD
Sbjct: 242 KARGINVTCEVAPHHILLTDDDIPKDNGYYKMNPPLRNKEDQAALLVGLLDGTIDLIATD 301
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTD-IFSLEMLVKLMSENVAKIFNL 359
HAPH +EK G++ ++FGI GSETAF+ LYTKFVK D +F+LE L+ +S+ A+ F L
Sbjct: 302 HAPHAKKEKQGGMKGAAFGITGSETAFSTLYTKFVKKDKVFTLEQLLSWLSDKPAEAFGL 361
Query: 360 P-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G LE ADI + D+E E TI +++ SKG NTP+ +KV G V+T+ NGK+ Y
Sbjct: 362 KDAGVLEPGKNADIAIFDIEHEATIEEKDYKSKGVNTPFTGQKVYGETVMTMVNGKVVY 420
>gi|148543363|ref|YP_001270733.1| dihydroorotase, multifunctional complex type [Lactobacillus reuteri
F275]
gi|148530397|gb|ABQ82396.1| dihydroorotase, multifunctional complex type [Lactobacillus reuteri
F275]
Length = 430
Score = 374 bits (960), Expect = e-102, Method: Composition-based stats.
Identities = 194/425 (45%), Positives = 274/425 (64%), Gaps = 4/425 (0%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHVHW 59
+LL N + + N + K ++LI D KI+ I E+I V +D +D+ + +T G ID HVH
Sbjct: 5 ILLTNGQRIYNDELVKSEVLIVDGKIKAIGEHIQVPSDAEKVDLDNGLITPGLIDIHVHL 64
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG++ KET+ T S+AAA GGFTT+ M NLNP D+ E +Q++ + +++ + Y
Sbjct: 65 REPGYTNKETIATGSKAAAHGGFTTIAAMANLNPTCDTPEKFKEQVDRNEKAGLVKILQY 124
Query: 120 GAITKEEYGRELSDM-EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+T G++ ++ E A F+DDG G+Q A V+Y+AM +K+N + H +DN
Sbjct: 125 SPVTVGRAGKQAVNVAEQYAAGARLFSDDGAGIQDAGVVYQAMQQLAKVNAPLCDHAQDN 184
Query: 179 SLIRGGAMHEGKRSAE-LGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L + G +++G A+ L + G+P+I E+ QIAR++++A+A HYHVCH+S KES+ +
Sbjct: 185 QLAQNGVINDGATIAKKLALPGMPAISETAQIARNLVIAQATGVHYHVCHVSTKESIDLI 244
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K+ I VTCEVTPHHLL D DIKED+ +KMNPPLR R D+ A + G+LDGTID I
Sbjct: 245 RHAKQQGINVTCEVTPHHLLLADADIKEDDAEFKMNPPLRQRLDQQACLIGLLDGTIDCI 304
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPHT EK +G KS GIVGSETAF LYT FVKT IF+L L+ M+ IF
Sbjct: 305 ATDHAPHTDAEKQQGFLKSPNGIVGSETAFALLYTHFVKTGIFTLAQLIDWMAVKPQAIF 364
Query: 358 NLP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
NL G L+ ADI V D++ + I P++F SKG NTP+ E+V G+ T +GK+
Sbjct: 365 NLDNAGLLKVGDPADIAVFDIDHQDVIQPDQFFSKGHNTPFVGEQVYGMTKRTYVDGKLV 424
Query: 417 YIDKE 421
Y++ E
Sbjct: 425 YLEGE 429
>gi|141553194|gb|ABI26403.2| dihydroorotase and related cyclic amidohydrolases [Lactobacillus
reuteri]
Length = 430
Score = 374 bits (959), Expect = e-102, Method: Composition-based stats.
Identities = 193/425 (45%), Positives = 273/425 (64%), Gaps = 4/425 (0%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHVHW 59
+LL N + + N + K ++LI D KI+ I E+I +D +D+ + +T G ID HVH
Sbjct: 5 VLLTNGRRIYNDELVKTEVLIVDGKIKAIGEHIQAPSDAEKVDLDNGLITPGLIDVHVHL 64
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG++ KET+ T S+AAA GGFTT+ M NLNP D+ E +Q++ + +++ + Y
Sbjct: 65 REPGYTNKETIATGSKAAAHGGFTTIAAMANLNPTCDTPEKFKEQVDRNEKAGLVKILQY 124
Query: 120 GAITKEEYGRELSDM-EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+T G++ ++ E A F+DDG G+Q A V+Y+AM +K+N + H +DN
Sbjct: 125 SPVTVGRAGKQAVNVAEQYAAGARLFSDDGAGIQDAGVVYQAMQQLAKVNAPLCDHAQDN 184
Query: 179 SLIRGGAMHEGKRSAE-LGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L + G +++G A+ L + G+P+I E+ QIAR++++A+A HYHVCH+S KES+ +
Sbjct: 185 QLAQNGVINDGATIAKKLALPGMPAISETAQIARNLVIAQATGVHYHVCHVSTKESIDLI 244
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K+ I VTCEVTPHHLL D DIKED+ +KMNPPLR R D+ A + G+LDGTID I
Sbjct: 245 RHAKQQGINVTCEVTPHHLLLADADIKEDDAEFKMNPPLRQRLDQQACLIGLLDGTIDCI 304
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPHT EK +G KS GIVGSETAF LYT FVKT IF+L L+ M+ IF
Sbjct: 305 ATDHAPHTDAEKQQGFLKSPNGIVGSETAFALLYTHFVKTGIFTLAQLIDWMAVKPQAIF 364
Query: 358 NLP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
NL G L+ ADI V D++ + I P++F SKG NTP+ E+V G+ T +GK+
Sbjct: 365 NLDNAGLLKVGDPADIAVFDIDHQDVIQPDQFFSKGHNTPFVGEQVYGMTKRTYVDGKLV 424
Query: 417 YIDKE 421
Y++ E
Sbjct: 425 YLEGE 429
>gi|92089939|ref|ZP_01274858.1| Dihydroorotase multifunctional complex type [Lactobacillus reuteri
100-23]
gi|91803283|gb|EAS88163.1| Dihydroorotase multifunctional complex type [Lactobacillus reuteri
100-23]
Length = 430
Score = 371 bits (952), Expect = e-101, Method: Composition-based stats.
Identities = 193/425 (45%), Positives = 272/425 (64%), Gaps = 4/425 (0%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHVHW 59
+LL N + + N + K ++LI D KI+ I E+I +D ID+ + +T G ID HVH
Sbjct: 5 ILLTNGQRIYNDELVKSEVLIVDGKIKAIGEHIQAPSDAEKIDLDNGLITPGLIDVHVHL 64
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG++ KET+ T S+AAA GGFTT+ M NLNP D+ E +Q++ + +++ + Y
Sbjct: 65 REPGYTNKETIATGSKAAAHGGFTTIAAMANLNPTCDTPEKFKEQVDRNEKAGLVKILQY 124
Query: 120 GAITKEEYGRELSDM-EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+T G++ ++ E A F+DDG G+Q A V+Y+AM +K+N + H +DN
Sbjct: 125 SPVTVGRAGKQAVNVAEQYAAGARLFSDDGAGIQDAGVVYQAMQQLAKVNAPLCDHAQDN 184
Query: 179 SLIRGGAMH-EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L + G ++ E + +L + G+P+I E+ QIAR++++A+A HYHVCH+S KES+ +
Sbjct: 185 QLAQNGVINDEATIAKKLALPGMPAISETAQIARNLVIAQATGVHYHVCHVSTKESIDLI 244
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K+ I VTCEVTPHHLL D DIKED+ +KMNPPLR R D+ A + G+LDGTID I
Sbjct: 245 RHAKQQGINVTCEVTPHHLLLADADIKEDDAEFKMNPPLRQRLDQQACLIGLLDGTIDCI 304
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPHT EK +G KS GIVGSETAF LYT FVKT IF+L L+ M+ IF
Sbjct: 305 ATDHAPHTDAEKQQGFLKSPNGIVGSETAFALLYTHFVKTGIFTLAQLIDWMAVKPQAIF 364
Query: 358 NLP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
NL G L+ ADI V D++ + I P++F SKG NTP+ E+V G+ T +GK+
Sbjct: 365 NLDNAGLLKVGDPADIAVFDIDHQDVIQPDQFFSKGHNTPFVGEQVYGMTKRTYVDGKLV 424
Query: 417 YIDKE 421
Y++ E
Sbjct: 425 YLEGE 429
>gi|116494940|ref|YP_806674.1| Dihydroorotase [Lactobacillus casei ATCC 334]
gi|116105090|gb|ABJ70232.1| Dihydroorotase [Lactobacillus casei ATCC 334]
Length = 421
Score = 370 bits (949), Expect = e-100, Method: Composition-based stats.
Identities = 195/419 (46%), Positives = 274/419 (65%), Gaps = 3/419 (0%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHVHW 59
ML+K+ I+ + ++ DI I D I I +++ D E ID V G ID HVH+
Sbjct: 1 MLIKHAHIVSDTEYM-ADIQITDHIISAIGQSLAPRDHEQVIDATGAIVMPGLIDVHVHF 59
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPGF+ KET+ T + AAA GGFTTV+ M NL PVPD+VETL LE + D+ I + +
Sbjct: 60 REPGFTDKETIKTGAAAAAHGGFTTVVAMSNLKPVPDTVETLKPLLEKNQTDAKITVLQF 119
Query: 120 GAITKEEYGRELSDMEDIADKVFA-FTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
IT + + ++ DM + F++DG GVQ A+ MY+AM +KL+ IVAH ED
Sbjct: 120 APITHDLHSDQVVDMAALQAAGALGFSNDGVGVQDADTMYQAMQQAAKLHAPIVAHIEDA 179
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL+ GG ++ G + +L + GI + ES+Q+ARD+ LA A HYH CH+S ++SV +R
Sbjct: 180 SLMHGGVINAGPVAKKLNLPGIINQTESSQLARDLELAAATGVHYHACHVSTRQSVDLIR 239
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
E KK + VT EV+PHHLL + +I DN M+KMNPPLR R D AL+ G+ DGT+D+IA
Sbjct: 240 EAKKRGVNVTAEVSPHHLLLDENNIPGDNPMFKMNPPLRSRADHLALLEGLQDGTLDMIA 299
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPHT EK + ++FGIVGSETAF+ LYTK VK+ +F+L+ L+ MS A+ F+
Sbjct: 300 TDHAPHTAAEKTGSFKTAAFGIVGSETAFSTLYTKLVKSKMFTLKQLIARMSTIPAEKFD 359
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
LP G + + AD+ ++DL+ TI+P ++ SKG+N+P+ +KVNG + TIS G+IAY
Sbjct: 360 LPGGHITVSGPADLTIMDLDTPYTIDPADWFSKGKNSPFIGDKVNGQTLYTISQGQIAY 418
>gi|28379202|ref|NP_786094.1| dihydroorotase [Lactobacillus plantarum WCFS1]
gi|29337219|sp|P77884|PYRC_LACPL Dihydroorotase (DHOase)
gi|28272040|emb|CAD64945.1| dihydroorotase [Lactobacillus plantarum WCFS1]
gi|114049524|emb|CAJ75870.1| PyrC protein [Lactobacillus plantarum subsp. plantarum]
Length = 430
Score = 369 bits (947), Expect = e-100, Method: Composition-based stats.
Identities = 188/421 (44%), Positives = 266/421 (63%), Gaps = 5/421 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVT---DENTIDVKDRFVTAGFIDAHVH 58
L+KN ++ + G+ + DILI + +I+ I + ++ I FV+ GF+D HVH
Sbjct: 4 LIKNAQVWQAGQLQTTDILIAEGRIKAIGHQLHDQFGPADHVICADQHFVSPGFVDVHVH 63
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
R+PG + KET+ T + AAA GGFTTV MPN++PVPD+ E + + + ++ +
Sbjct: 64 LRDPGQTAKETIATGTLAAAHGGFTTVGAMPNVDPVPDTPERVATMVARNQQEAHVHVAQ 123
Query: 119 YGAITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
Y +IT +L D I A FA ++DG GVQ+A M+ AM +K+ + AH ED
Sbjct: 124 YASITTGRTSEQLVDFAGIKAAGAFAVSNDGSGVQTAGTMFAAMQGAAKVGLPLAAHVED 183
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
+SL G M+ G + LG+ GI ++ E+ Q+ARD++LAEA+ HYHVCH+S ES+R +
Sbjct: 184 DSLYHHGVMNAGPVADRLGLPGINNVSEAAQVARDVMLAEASGVHYHVCHVSTAESLRVI 243
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K I VTCEV+PHHLL CDEDI DN M KMNPPLR +DR AL+AG+LDGTID+I
Sbjct: 244 RNAKAAGINVTCEVSPHHLLLCDEDITMDNPMLKMNPPLRSAKDRAALVAGLLDGTIDMI 303
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPHT EK ++ ++FGI G ETAF LYT VKT + +L L++LMS A++F
Sbjct: 304 ATDHAPHTDAEKQGSMKTAAFGITGIETAFATLYTALVKTRLLTLGRLIELMSTRPAELF 363
Query: 358 NL-PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
L G+L + AD+ +IDL+ + I LSKG N+P+ V G ++T+ +GK+A
Sbjct: 364 GLNTAGRLVVGAPADLTIIDLDHQYEIEAATMLSKGHNSPFIGWPVYGNVLMTLVDGKLA 423
Query: 417 Y 417
Y
Sbjct: 424 Y 424
>gi|1514601|emb|CAA91003.1| dihydroorotase, carbamoylaspartic dehydrase [Lactobacillus
plantarum]
Length = 430
Score = 367 bits (941), Expect = 1e-99, Method: Composition-based stats.
Identities = 187/421 (44%), Positives = 265/421 (62%), Gaps = 5/421 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVT---DENTIDVKDRFVTAGFIDAHVH 58
L+KN ++ + G+ + DILI + +I+ I + ++ I FV+ GF+D HVH
Sbjct: 4 LIKNAQVWQAGQLQTTDILIAEGRIKAIGHQLHDQFGPADHVICADHHFVSPGFVDVHVH 63
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
R+PG + KET+ T + AAA GGFTTV MPN++PVPD+ E + + + ++ +
Sbjct: 64 LRDPGQTAKETIATGTLAAAHGGFTTVGAMPNVDPVPDTPERVATMVARNQQEAHVHVAQ 123
Query: 119 YGAITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
Y +IT +L D I A FA ++DG GVQ+A M+ AM +K+ + AH ED
Sbjct: 124 YASITTGRTSEQLVDFAGIKAAGAFAVSNDGSGVQTAGTMFAAMQGAAKVGLPLAAHVED 183
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
+SL G M+ G + LG+ GI ++ E+ Q+ARD++LAEA+ HYHVCH+S ES+R +
Sbjct: 184 DSLYHHGVMNAGPVADRLGLPGINNVSEAAQVARDVMLAEASGVHYHVCHVSTAESLRVI 243
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K I VTCEV+PHHLL CDEDI DN M KMNPPLR +DR AL+AG+LDGTID+I
Sbjct: 244 RNAKAAGINVTCEVSPHHLLLCDEDITMDNPMLKMNPPLRSAKDRAALVAGLLDGTIDMI 303
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPHT EK ++ ++FGI G ETAF LYT VKT + +L L++LMS ++F
Sbjct: 304 ATDHAPHTDAEKQGSMKTAAFGITGIETAFATLYTALVKTRLLTLGRLIELMSTRPTELF 363
Query: 358 NL-PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
L G+L + AD+ +IDL+ + I LSKG N+P+ V G ++T+ +GK+A
Sbjct: 364 GLNTAGRLVVGAPADLTIIDLDHQYEIEAATMLSKGHNSPFIGWPVYGNVLMTLVDGKLA 423
Query: 417 Y 417
Y
Sbjct: 424 Y 424
>gi|81428564|ref|YP_395564.1| Dihydroorotase [Lactobacillus sakei subsp. sakei 23K]
gi|78610206|emb|CAI55255.1| Dihydroorotase [Lactobacillus sakei subsp. sakei 23K]
Length = 429
Score = 365 bits (936), Expect = 4e-99, Method: Composition-based stats.
Identities = 196/422 (46%), Positives = 262/422 (62%), Gaps = 6/422 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDD-KIEKISENIDVTDENT---IDVKDRFVTAGFIDAHV 57
L++N ++L + + K DI I + +I I I TDE T D + V+AG ID HV
Sbjct: 4 LIQNGQLLIDDQLVKRDIAIDEKGRITAIEAQITPTDEPTETIFDAQGALVSAGLIDGHV 63
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H+R+PGF+ KET+ T S+AAA GG+T+V+ MPNLNPVPD++ + + ++ +
Sbjct: 64 HFRDPGFTDKETLQTGSQAAAHGGYTSVIAMPNLNPVPDNLSDFKTLVARNQTETSVHTY 123
Query: 118 PYGAITKEEYGRELSDM-EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
+ IT + +L DM A FT+DG GVQ A MY AM + ++ IVAH E
Sbjct: 124 QFAPITGDLVNNDLVDMPAFKAAGAAGFTNDGHGVQDAQTMYLAMQQAAAIDAPIVAHVE 183
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D SL+ GG +H+G + L + GIPS+ ES Q+ARDI LA A HYH+CHIS KE+V
Sbjct: 184 DISLVNGGVIHDGAAAKRLNVPGIPSVSESAQVARDIELARATGVHYHICHISTKETVAL 243
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
VR K + + +TCEVTPHHLL D I D+ M KMNPPLR DR +L AG++DGTID+
Sbjct: 244 VRRAKADGVNITCEVTPHHLLLDDRSIISDDTMLKMNPPLRTLADRQSLWAGLMDGTIDV 303
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPHT EK + + ++ FGIVGSETAF+ LYT V FSL L+ M+ A++
Sbjct: 304 IATDHAPHTAAEKSQSLLQAPFGIVGSETAFSLLYTHLVVNGPFSLAQLLAKMTTVPAQV 363
Query: 357 FNLP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
FNLP G+L ADI V +L + TI +F SKG NTP+ E V G LT+ G++
Sbjct: 364 FNLPAAGQLRVGDQADIAVFNLTQPTTIQATDFQSKGHNTPFIGETVLGGTELTLVAGQV 423
Query: 416 AY 417
AY
Sbjct: 424 AY 425
>gi|116492117|ref|YP_803852.1| Dihydroorotase [Pediococcus pentosaceus ATCC 25745]
gi|116102267|gb|ABJ67410.1| Dihydroorotase [Pediococcus pentosaceus ATCC 25745]
Length = 425
Score = 364 bits (935), Expect = 6e-99, Method: Composition-based stats.
Identities = 185/419 (44%), Positives = 273/419 (65%), Gaps = 2/419 (0%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+LLKN +++K+ + +K D+L+++D+I +I I+V E IDVK++ + G +D HVH+R
Sbjct: 3 VLLKNARVIKSHQVQKTDVLVENDRITQIQPEINVEAEQIIDVKNQLLMPGLVDIHVHFR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
+PG + KE V + S AA +GGFTTV+TMPN++PVPD+ E + ++ + + YG
Sbjct: 63 DPGQTDKEDVVSGSAAAVKGGFTTVLTMPNVDPVPDTPEKMTAMVKHNQTAGSLHIGQYG 122
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+ITK+ EL D + + + AF++DG G+Q+A MY+AML ++ + AH ED S
Sbjct: 123 SITKKRTSEELVDFKALKEAGAVAFSNDGNGIQTAETMYQAMLQIKEVGLPLAAHVEDES 182
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
L++ G M++G + +LG+ GI + E+ Q+ARD+ +A HYHVCH+S SV +R
Sbjct: 183 LMQHGVMNQGTVAEKLGLPGISELAETAQLARDLEIARNTGAHYHVCHVSKARSVELIRR 242
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
+++ + VT EV PHHL + I DN M KMNPPLR EDR AL+ G+LDGTI +IAT
Sbjct: 243 AQRDGVHVTAEVAPHHLFLDETMISMDNPMMKMNPPLRTLEDRQALLGGLLDGTIGMIAT 302
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT+++K ++ +SFGI G ETAF LYTK VK + ++E LV+ MS A+IFNL
Sbjct: 303 DHAPHTVKDKAGSMKTASFGITGLETAFPLLYTKLVKPGLCTVEQLVEWMSIQPAEIFNL 362
Query: 360 -PYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+LE AD+ V+++E E I +F SKG N+P+ +KV G LT+ GKI Y
Sbjct: 363 KAAGQLEVGDVADLTVMNVEDEYEIKEADFASKGINSPFIGQKVYGQTQLTMVAGKIVY 421
>gi|42519203|ref|NP_965133.1| dihydroorotase [Lactobacillus johnsonii NCC 533]
gi|41583490|gb|AAS09099.1| dihydroorotase [Lactobacillus johnsonii NCC 533]
Length = 425
Score = 359 bits (922), Expect = 1e-97, Method: Composition-based stats.
Identities = 187/419 (44%), Positives = 263/419 (62%), Gaps = 5/419 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
++KN + +NG K D+LI KI+ I D+ E ID V+ G +D HVH+R+
Sbjct: 4 VIKNGTVYQNGHLIKADVLIDGQKIKAIG--TDLEGEEIIDASGMIVSPGLVDVHVHYRD 61
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG + KE + T S+AAARGGFTTV MPN+ PVP++ E ++K + + ++ + YG
Sbjct: 62 PGQTYKEDIKTGSQAAARGGFTTVGAMPNVTPVPNTAELMDKMVRENQKKGLVHILQYGP 121
Query: 122 ITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
+T +E + D + FA ++DG GVQSA MY AM + N I AH +D+SL
Sbjct: 122 VTNDETTDIIPDYAALKKAGAFALSNDGHGVQSAQTMYLAMQKAKENNLIIAAHAQDDSL 181
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
G ++EG + +L + + + E+TQIARD+LLA+ HYH+CH+S K SV VR
Sbjct: 182 FNKGIVNEGIAAEKLDLPPVTELAETTQIARDLLLAQKTGVHYHICHVSTKTSVELVRLA 241
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K I+VTCEV PHH+L D DI EDN +KMNPPLR +ED+ AL+ G+LDGTID+IATD
Sbjct: 242 KARGIKVTCEVAPHHILLTDSDIPEDNAYFKMNPPLRSKEDQVALLVGLLDGTIDLIATD 301
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTD-IFSLEMLVKLMSENVAKIFNL 359
HAPH EK G+ ++FGI GSETAF+ LYT+FVK + +F+LE L+ L+++ A +F +
Sbjct: 302 HAPHAKAEKQGGMRGAAFGITGSETAFSTLYTRFVKEEKVFTLEQLLSLLTDKPATVFGI 361
Query: 360 P-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G L ADI + D+E + I ++F SKG NTP+ KV G V+T +GK+ Y
Sbjct: 362 ENAGLLAPGENADIAIFDIEHQREIKEDDFKSKGVNTPFTGHKVYGETVMTFVDGKVVY 420
>gi|116629728|ref|YP_814900.1| Dihydroorotase [Lactobacillus gasseri ATCC 33323]
gi|116095310|gb|ABJ60462.1| Dihydroorotase [Lactobacillus gasseri ATCC 33323]
Length = 425
Score = 352 bits (902), Expect = 4e-95, Method: Composition-based stats.
Identities = 191/419 (45%), Positives = 268/419 (63%), Gaps = 5/419 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
++KN + +NG+ K D+LI+ KI+ I ++D E ID + V+ G +D HVH+R+
Sbjct: 4 VIKNGTVYQNGRLIKADVLIEGKKIKAIGTDLDA--EKIIDAQGMLVSPGLVDVHVHYRD 61
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG + KE + T S AAARGGFTTV MPN+ PVP++ E + K +E K+ V+ YG
Sbjct: 62 PGQTYKEDIKTGSEAAARGGFTTVGAMPNVTPVPNTPELMKKMVEENKHKGVVHIFQYGP 121
Query: 122 ITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
IT +E + D + FA ++DG GVQ+A MY AM + N I H +D+SL
Sbjct: 122 ITNDETTDIIPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQKAKENNLIIATHAQDDSL 181
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
G ++EG + +L + + + E+TQIARD+LLA+ HYH+CH+S K SV VR
Sbjct: 182 FNKGIVNEGVAAKKLDLPPVTELAETTQIARDLLLAQKTGVHYHICHVSTKTSVELVRLA 241
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K I VTCEV PHH+L D DI +DNG +KMNPPLR +ED+ AL+ G+LDGTID+IATD
Sbjct: 242 KARGINVTCEVAPHHILLTDSDIPKDNGYFKMNPPLRNKEDQAALLVGLLDGTIDLIATD 301
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTD-IFSLEMLVKLMSENVAKIFNL 359
HAPH EK G++ ++FGI GSETAF+ LYTKFVK + + SLE L+ L+S+ AK+F +
Sbjct: 302 HAPHAKSEKQGGMKNAAFGITGSETAFSTLYTKFVKEEKVLSLEQLLALLSDKPAKVFGI 361
Query: 360 P-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G LE AD+ + D+E + I +F SKG NTP+ +KV G V+T+ +G++ Y
Sbjct: 362 ENAGVLEPGKNADVAIFDIEHKNEIKEADFKSKGVNTPFTGQKVYGETVMTLVDGEVVY 420
>gi|118586673|ref|ZP_01544111.1| dihydroorotase [Oenococcus oeni ATCC BAA-1163]
gi|118432858|gb|EAV39586.1| dihydroorotase [Oenococcus oeni ATCC BAA-1163]
Length = 430
Score = 342 bits (878), Expect = 2e-92, Method: Composition-based stats.
Identities = 187/425 (44%), Positives = 257/425 (60%), Gaps = 4/425 (0%)
Query: 2 LLKNCKILKN-GKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L+KN +IL + F K D+LI+ KI I + + + +D K + G ID HVH+R
Sbjct: 5 LIKNAQILVDENSFLKRDLLIEKGKISAIGDGLSNKTDFIVDAKGALLLPGLIDVHVHFR 64
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGF +KET+ + S+AAARGGFTTV MPNLNPV D+VE + + + D +I+ Y
Sbjct: 65 EPGFPEKETIASGSKAAARGGFTTVFAMPNLNPVVDNVEVFKQVQALNQQDGIIKIKQYA 124
Query: 121 AITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AI+ ++ ++ + A AFT+DG+GVQ+A+ MY+AM K +VAH EDNS
Sbjct: 125 AISTGLTANKIDNIPALSALGAIAFTNDGKGVQTADTMYQAMRAAKAAGKILVAHVEDNS 184
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GG ++ G + LG G + E++Q+ARD+++A+ HYHV H+SA ESV +R
Sbjct: 185 LIHGGVINAGLTAEALGFPGATKLSETSQLARDLMIAKTTGAHYHVAHVSAAESVELIRI 244
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K++ I VT EV+PHHLL D I DN + KMNPPLR DR AL+AG+LDGTIDI+AT
Sbjct: 245 AKEHQINVTAEVSPHHLLLDDSMITNDNSLMKMNPPLRSPRDRAALLAGLLDGTIDIVAT 304
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK + I + G+ G ET+F LYT VK I SL L+K M+ A IF+L
Sbjct: 305 DHAPHTKEEKAQSILTAPNGVTGIETSFQLLYTHLVKPGIMSLRQLLKAMNRRPADIFSL 364
Query: 360 P--YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
++ AD+ + D++ I EF SK N+P+ KV G T NG+ Y
Sbjct: 365 KDVAREISVGEVADLALFDIQHLHEIKANEFASKASNSPFIGWKVYGQTERTWVNGQQVY 424
Query: 418 IDKEE 422
+E
Sbjct: 425 AKGDE 429
>gi|116490362|ref|YP_809906.1| Dihydroorotase [Oenococcus oeni PSU-1]
gi|116091087|gb|ABJ56241.1| Dihydroorotase [Oenococcus oeni PSU-1]
Length = 430
Score = 339 bits (870), Expect = 2e-91, Method: Composition-based stats.
Identities = 186/425 (43%), Positives = 255/425 (60%), Gaps = 4/425 (0%)
Query: 2 LLKNCKIL-KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L+KN +IL F K D+ I+ KI I + + + +D K + G ID HVH+R
Sbjct: 5 LIKNAQILVGENSFLKRDLFIEKGKISAIGDGLSNKADFIVDAKGALLLPGLIDVHVHFR 64
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGF +KET+ + S+ AARGGFTTV MPNLNPV D+VE + + + D +I+ Y
Sbjct: 65 EPGFPEKETIASGSKVAARGGFTTVFAMPNLNPVIDNVEVFKQVQALNQQDGIIKIKQYA 124
Query: 121 AITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AI+ ++ ++ + A AFT+DG+GVQ+A+ MY+AML K +VAH EDNS
Sbjct: 125 AISTGLTANKIDNIPALSALGAIAFTNDGKGVQTADTMYQAMLAAKAAGKVLVAHVEDNS 184
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GG ++ G S LG G + E++Q+ARD+++A+A YH+ H+SA ESV +R
Sbjct: 185 LIHGGVVNAGLASKNLGFPGAKKLSETSQLARDLMIAKATGAQYHMAHVSAAESVELIRI 244
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K++ I VT EV+PHHLL D I DN + KMNPPLR +DR AL+AG+LDGTIDI+AT
Sbjct: 245 AKEHRIDVTAEVSPHHLLLDDSMITNDNSLMKMNPPLRSPDDRAALLAGLLDGTIDIVAT 304
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPHT EEK + I + G+ G ET+F LYT VK I SL L+K M++ A IF L
Sbjct: 305 DHAPHTKEEKAQSILTAPNGVTGIETSFQLLYTHLVKPGIMSLRQLLKAMNQRPADIFAL 364
Query: 360 P--YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
++ AD+ + D+ I EF SK N+P+ KV G T NG+ Y
Sbjct: 365 KDVAREIAIGQVADLALFDIRHLHEIKANEFASKASNSPFIGWKVYGQTERTWVNGQQVY 424
Query: 418 IDKEE 422
+E
Sbjct: 425 AKGDE 429
>gi|154505061|ref|ZP_02041799.1| hypothetical protein RUMGNA_02571 [Ruminococcus gnavus ATCC 29149]
gi|153794540|gb|EDN76960.1| hypothetical protein RUMGNA_02571 [Ruminococcus gnavus ATCC 29149]
Length = 425
Score = 333 bits (854), Expect = 1e-89, Method: Composition-based stats.
Identities = 173/402 (43%), Positives = 254/402 (63%), Gaps = 2/402 (0%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
D+L++D IEK+ +N+ + ID +V GFID HVH R+PG ++KET+ T AA
Sbjct: 22 DVLVRDTDIEKVEKNLQAEADRVIDASGCYVMPGFIDLHVHLRDPGLTQKETLSTGGMAA 81
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI 137
ARGG TTV MPN PV D+ E + + K +S++ I G++T E G ELSD+E +
Sbjct: 82 ARGGVTTVCAMPNTKPVIDTKEKVEEVHRRAKEESLVHVIQLGSMTMGECGEELSDIEGM 141
Query: 138 ADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELG 196
A +A ++DG+ V +A + +AM + + I +HCED S++ GG M+ GKR+ ELG
Sbjct: 142 AQAGCYALSEDGKSVMNAFLFRKAMRKAKENDLLIFSHCEDISMVEGGVMNAGKRAEELG 201
Query: 197 IKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHL 256
+KGI + E +ARDIL+A+ + H+CH S +SVR +++ K+ ++VT EV PHH
Sbjct: 202 VKGITNSVEDVIVARDILIAKELDATLHLCHCSTADSVRMIKDAKEAGLKVTGEVCPHHF 261
Query: 257 LSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKS 316
+ DEDI E+NG+WKMNPPLR + D AL G+ DG +D+I+TDHAPH M EK + +E++
Sbjct: 262 ILTDEDIPENNGIWKMNPPLRSKADVEALRQGLKDGVMDVISTDHAPHMMSEKDKPMEQA 321
Query: 317 SFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGKLEENSFADIVVI 375
+FGIVG ET+ YT+ V+ + ++ + + MS N AKI L G + ADIVV
Sbjct: 322 AFGIVGLETSACLTYTELVEKGVLTVMQMAEKMSYNPAKILGLKDRGSVSAGKKADIVVF 381
Query: 376 DLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
D +E I+ + F SKG+NTP+ +V G T+++GKI Y
Sbjct: 382 DPRREYQIDVDTFASKGKNTPFDGWEVKGEVCCTLADGKIVY 423
>gi|154483488|ref|ZP_02025936.1| hypothetical protein EUBVEN_01192 [Eubacterium ventriosum ATCC
27560]
gi|149735740|gb|EDM51626.1| hypothetical protein EUBVEN_01192 [Eubacterium ventriosum ATCC
27560]
Length = 405
Score = 329 bits (843), Expect = 2e-88, Method: Composition-based stats.
Identities = 174/405 (42%), Positives = 253/405 (62%), Gaps = 1/405 (0%)
Query: 17 VDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
+DI ++D I++ +E+I+ + ID +V G ID HVH+R+PG + KE + T S+A
Sbjct: 1 MDIFVEDGIIKEKAESIEKQADTVIDAAGCYVMPGLIDLHVHFRDPGLTYKEDIETGSKA 60
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMED 136
AA+GGFTTV MPN PV D+VET+ +E + + +P GA+TK G E++D+E+
Sbjct: 61 AAKGGFTTVCCMPNTKPVVDNVETVKYIIEKGEKTGLTNVLPVGAVTKNMAGVEITDVEE 120
Query: 137 IADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAEL 195
+ + A ++DG+ V ++ V +AM +K N ++AHCED +L+ GG ++ G +S+EL
Sbjct: 121 LKKAGICAISEDGKSVMNSGVYRKAMKNAAKANVPVLAHCEDINLVEGGVINLGDKSSEL 180
Query: 196 GIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
G+KGI + E RDI+LA+ H+CH S K+SV V+ K+ I+VT EV PHH
Sbjct: 181 GVKGISNAVEDVIAMRDIMLAKETGATLHLCHCSTKDSVEMVKRAKEEGIKVTAEVCPHH 240
Query: 256 LLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEK 315
C +DI ++G +KMNPPLR RED ALI G+ D +D+I+TDHAPH+ EEK + +E
Sbjct: 241 FSMCSDDITSNDGNFKMNPPLRAREDMEALIKGLQDDIMDVISTDHAPHSAEEKAKDLEH 300
Query: 316 SSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVI 375
+ FGIVG ET+ T VK + + MS N AK+ +P G L+E ADI +I
Sbjct: 301 APFGIVGLETSVALTVTNLVKKGYLTPMQMAAKMSYNPAKVLGIPKGTLDEGKIADITII 360
Query: 376 DLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
D +KE TI+ F SKG+NTP+ KV+G TI NGK+ Y +K
Sbjct: 361 DPDKEYTIDVNTFESKGKNTPFDGYKVSGEVEYTILNGKVVYSNK 405
>gi|50842481|ref|YP_055708.1| dihydroorotase [Propionibacterium acnes KPA171202]
gi|50840083|gb|AAT82750.1| dihydroorotase [Propionibacterium acnes KPA171202]
Length = 445
Score = 329 bits (843), Expect = 2e-88, Method: Composition-based stats.
Identities = 170/405 (41%), Positives = 249/405 (61%), Gaps = 6/405 (1%)
Query: 19 ILIKDDKIEKISEN----IDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTAS 74
+LI+D++IE IS +D D +D+ VT G +D HVH REPG KET+ + +
Sbjct: 23 LLIRDERIEAISRGRSNALDGADAEVVDLGGALVTPGMVDLHVHLREPGQEHKETIASGT 82
Query: 75 RAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDM 134
AAARGG+TT+ MPN P P S E + ++ +V+R +P IT G +L D+
Sbjct: 83 AAAARGGWTTICAMPNTVPDPHSPELMADLNRRVEESAVVRVLPIAPITVGLTGNDLVDV 142
Query: 135 EDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSA 193
E + AF++DG+GVQ A VMY+AM + +++ I AH ED SL+RGG +++G+R+
Sbjct: 143 EALTRAGAVAFSNDGKGVQLAGVMYDAMRSAAAVDRPIAAHAEDESLVRGGVINDGRRAR 202
Query: 194 ELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTP 253
ELG+ + + E+ Q+ARD+++AE HYH+CH S ++S+R +R G+++ VT E P
Sbjct: 203 ELGLPPMTRLTETVQVARDVMIAEETGAHYHLCHASTRQSIRTLRRGREDGANVTGEAAP 262
Query: 254 HHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGI 313
HHLL D+DI +D+G +KMNPPLR R+D NA++ G+ DGT+ IATD+APH EEK
Sbjct: 263 HHLLLADDDIPDDDGFYKMNPPLRTRDDLNAMVEGLCDGTLTCIATDNAPHAAEEKACSF 322
Query: 314 EKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGKLEENSFADI 372
++FG++ +E F LYT FV F L+ LV ++ A+ F +P G+L AD+
Sbjct: 323 RDAAFGVITNEHTFALLYTNFVLDRRFRLDQLVDWLTIGPAETFGIPEAGRLRVGGPADL 382
Query: 373 VVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
DL E+TI P + GRNTP+A V G VLT+ G+ Y
Sbjct: 383 AAFDLRTEMTIIPGDGAGMGRNTPFAGRSVRGDCVLTMVGGQTVY 427
>gi|109645922|ref|ZP_01369842.1| dihydroorotase, multifunctional complex type [Desulfitobacterium
hafniense DCB-2]
gi|109643871|gb|EAT53424.1| dihydroorotase, multifunctional complex type [Desulfitobacterium
hafniense DCB-2]
Length = 434
Score = 326 bits (835), Expect = 2e-87, Method: Composition-based stats.
Identities = 175/412 (42%), Positives = 243/412 (58%), Gaps = 12/412 (2%)
Query: 18 DILIKDDKIEKISENI---DVTDE------NTIDVKDRFVTAGFIDAHVHWREPGFSKKE 68
D+LI + K+ ++ + + +V E ID ++ G ID H H REPG KE
Sbjct: 21 DVLIGEGKVLQLKKGLTEAEVKGECGETGWQEIDAAGSYLFPGLIDVHTHLREPGREDKE 80
Query: 69 TVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYG 128
+ + SRAA RGGFTT++ MPN P+ D + + K + + P AITK + G
Sbjct: 81 DIASGSRAAVRGGFTTILAMPNTTPILDQKALVEYVVNQGKKVGLAKVHPIAAITKGQAG 140
Query: 129 RELSDMEDIADKVFA-FTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
+EL +M ++A A F+DDGRGVQ +M A+ + +++HCED SL G MH
Sbjct: 141 KELVEMVELAAAGAAGFSDDGRGVQQGEMMRLALEYAKLTSCPVISHCEDESLAHKGVMH 200
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
G S LG+KGIPS ES +ARDILLAE + H+ HISAKESV +REGKK + V
Sbjct: 201 RGIVSTRLGLKGIPSSSESVMVARDILLAEESGGKLHLAHISAKESVALIREGKKRGVDV 260
Query: 248 TCEVTPHHLLSCDEDIKED--NGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHT 305
T EV PHHLL DE + +K+NPPLR EDR ALI G+LDGT+D++ATDHAPHT
Sbjct: 261 TAEVNPHHLLFTDEAVARTPYGTSYKVNPPLRREEDRQALIEGLLDGTLDMLATDHAPHT 320
Query: 306 MEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLE 365
EEK +++ FGI G ETA ++ + V T I +E+L+K S N A+ F LP G L+
Sbjct: 321 WEEKTNPFDQAPFGISGLETALAAVWQELVTTGILPIELLIKAWSMNPAQRFQLPGGTLK 380
Query: 366 ENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
AD+++ D E I+ E SKG+NTP+ +++ G PV +G++ +
Sbjct: 381 VGGPADLILFDPEHTELIDTEYLASKGKNTPFLGQRLQGFPVKVWVDGRLVH 432
>gi|147678146|ref|YP_001212361.1| dihydroorotase and related cyclic amidohydrolases [Pelotomaculum
thermopropionicum SI]
gi|146274243|dbj|BAF59992.1| dihydroorotase and related cyclic amidohydrolases [Pelotomaculum
thermopropionicum SI]
Length = 427
Score = 324 bits (831), Expect = 6e-87, Method: Composition-based stats.
Identities = 169/410 (41%), Positives = 238/410 (58%), Gaps = 2/410 (0%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVY 71
GK ++ D+ I D KI + +++ +D + V G ID HVH REPGF +ET+Y
Sbjct: 16 GKIEEKDVFIVDGKIARAGAHVNTAGAEVLDASGKLVVPGLIDMHVHLREPGFEARETIY 75
Query: 72 TASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGREL 131
T +RAAARGGFT+V MPN +PV D+ ++ ++ + P GAIT+ G EL
Sbjct: 76 TGTRAAARGGFTSVACMPNTSPVADNGAVISF-IKACGLKGAVNVYPIGAITRGSKGEEL 134
Query: 132 SDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGK 190
++M D+ + AF+DDG V +A +M A+ L +++HCED +L GG MHEG
Sbjct: 135 AEMGDMKEAGAVAFSDDGMPVMNAGLMRRALQYAGMLGMVVISHCEDKNLSAGGVMHEGY 194
Query: 191 RSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
S LG+KGIP+ E +ARDILLAE H+ H+S SVR +RE K +RVT E
Sbjct: 195 VSTMLGLKGIPASAEEVMVARDILLAEETGSRVHIAHVSTAGSVRLIREAKARGVRVTAE 254
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
V PHH DE + + K+NPPLR D A+ G+ DGTID+IATDHAPHT EEK
Sbjct: 255 VAPHHFTLTDEAVLGYDTSTKVNPPLRSAGDVAAVREGLADGTIDVIATDHAPHTEEEKD 314
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
+ + FG+VG ETA ++T+ V + + V M+ N A++ +P G LE + A
Sbjct: 315 VEYDLAPFGMVGLETAVGLVWTELVAAGVLTPLQAVVKMTLNPARVLGIPKGTLEPGADA 374
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
DI +ID + ++P F SKGRNTP+ + G+P TI G++ D+
Sbjct: 375 DITIIDPDLSEPVDPARFASKGRNTPFRGRLLKGLPWATIVGGRVVMQDR 424
>gi|89895607|ref|YP_519094.1| hypothetical protein DSY2861 [Desulfitobacterium hafniense Y51]
gi|89335055|dbj|BAE84650.1| hypothetical protein [Desulfitobacterium hafniense Y51]
Length = 434
Score = 320 bits (821), Expect = 8e-86, Method: Composition-based stats.
Identities = 175/429 (40%), Positives = 249/429 (58%), Gaps = 14/429 (3%)
Query: 3 LKNCKILK--NGKFKKVDILIKDDKIEKISENI---DVTDE------NTIDVKDRFVTAG 51
+KN +++ G D+LI + K+ ++ + + +V E ID ++ G
Sbjct: 4 IKNAQVVDPAQGLSGSYDVLIGEGKVLQLKKGLTEAEVKGECGEAEWQEIDAAGNYLFPG 63
Query: 52 FIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKND 111
ID H H REPG KE + + SRAA RGGFTT++ MPN P+ D + + K
Sbjct: 64 LIDVHTHLREPGREDKEDIASGSRAAVRGGFTTILAMPNTTPILDQKALVEYVVNQGKKV 123
Query: 112 SVIRAIPYGAITKEEYGRELSDMEDIADKVFA-FTDDGRGVQSANVMYEAMLMGSKLNKA 170
+ + P AITK + G+EL +M ++A A F+DDGRGVQ +M A+ +
Sbjct: 124 GLAKIHPIAAITKGQAGKELVEMVELAAAGAAGFSDDGRGVQQGEMMRLALEYAKLTSCP 183
Query: 171 IVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISA 230
+++HCED SL G MH G S LG++GIPS ES +ARDILLAE + H+ HISA
Sbjct: 184 VISHCEDESLAHKGVMHRGIVSTRLGLRGIPSSSESVMVARDILLAEESGGKLHLAHISA 243
Query: 231 KESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKED--NGMWKMNPPLRGREDRNALIAG 288
KESV +REGKK + VT EV PHHLL DE + +K+NPPLR EDR AL+ G
Sbjct: 244 KESVALIREGKKRGVDVTAEVNPHHLLFTDEAVARTPYGTSYKVNPPLRTEEDRQALLEG 303
Query: 289 VLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKL 348
+LDGT+D++ATDHAPHT EEK +++ FGI G ETA ++ + V T I +E+L+K
Sbjct: 304 LLDGTLDMLATDHAPHTWEEKTNPFDEAPFGISGLETALAAVWQELVTTGILPVELLIKA 363
Query: 349 MSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVL 408
S N A+ F LP G L+ + AD+++ D E I+ E SKG+NTP+ +++ G P
Sbjct: 364 WSMNPAQRFQLPGGTLKVGAPADLILFDPEHTELIDTEYLASKGKNTPFLGQRLQGFPSK 423
Query: 409 TISNGKIAY 417
G++ +
Sbjct: 424 VWVEGRLVH 432
>gi|134299538|ref|YP_001113034.1| dihydroorotase, multifunctional complex type [Desulfotomaculum
reducens MI-1]
gi|134052238|gb|ABO50209.1| dihydroorotase, multifunctional complex type [Desulfotomaculum
reducens MI-1]
Length = 427
Score = 315 bits (808), Expect = 3e-84, Method: Composition-based stats.
Identities = 163/405 (40%), Positives = 245/405 (60%), Gaps = 3/405 (0%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
DIL+++ I++I + D ++ I + +V GF+D HVH REPG+ KE + + +RAA
Sbjct: 22 DILVEEGMIKEIGQLSD-SEAEVIAAEGNYVCPGFMDMHVHLREPGYEYKEDIVSGTRAA 80
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI 137
A GGFT+V MPN NPV D+ ++ L +N + R P GA+TK G+EL++M D+
Sbjct: 81 AMGGFTSVACMPNTNPVADNAAIISHVLAKARN-AAARVFPIGALTKGSLGKELTEMADL 139
Query: 138 ADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELG 196
A +DDG V +A++M M S L +++HCEDN L GG MHEG SA LG
Sbjct: 140 KGAGAVALSDDGMPVMNADIMLRVMQYASMLEMTVISHCEDNKLSEGGQMHEGAVSAMLG 199
Query: 197 IKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHL 256
+KGIPS+ E +ARDILL+E C H+ HIS + SVR VR+ K+ + VT E TPHH
Sbjct: 200 LKGIPSLAEEIMVARDILLSEYTGCRLHLAHISTEGSVRLVRQAKERGVPVTAEATPHHF 259
Query: 257 LSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKS 316
+E ++ + K+NPPLR + D A+ G+ DGTID+IATDHAPH EK + +
Sbjct: 260 TLTEEAVQGYSTNAKVNPPLRRQTDVEAIKEGLRDGTIDVIATDHAPHAYHEKDVEFQYA 319
Query: 317 SFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVID 376
G++G ETA ++T+ V+ I ++ V ++ N ++ L G+L + A+I +ID
Sbjct: 320 PNGMIGLETAVGLIFTQLVQPGILTVPQAVAKLTCNPHRVLGLSGGRLLPGTPANITIID 379
Query: 377 LEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKE 421
+ ++P + LSK +NTP+ K+ G+PVLT+ +G + D++
Sbjct: 380 PKLSEVVDPTKLLSKSKNTPFGRWKLTGLPVLTMKDGLLVMRDRQ 424
>gi|106885627|ref|ZP_01352984.1| dihydroorotase, multifunctional complex type [Clostridium
phytofermentans ISDg]
gi|106766870|gb|EAT23592.1| dihydroorotase, multifunctional complex type [Clostridium
phytofermentans ISDg]
Length = 426
Score = 314 bits (805), Expect = 6e-84, Method: Composition-based stats.
Identities = 177/406 (43%), Positives = 247/406 (60%), Gaps = 7/406 (1%)
Query: 16 KVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASR 75
+ D+LI++ I K++ENI+ + ID ++V GFID HVH REPGF KET+ T +
Sbjct: 20 RYDLLIENKIISKVAENIEEPEATVIDASGKYVMPGFIDLHVHLREPGFEHKETIKTGAM 79
Query: 76 AAARGGFTTVMTMPNLNPVPDS---VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELS 132
AAA GG+TT+ MPN NP DS VE LN++ K+D+ I IP GA+T + G+EL+
Sbjct: 80 AAAAGGYTTICPMPNTNPAIDSKAMVELLNQK---AKSDAKIHIIPVGAVTVGQMGKELA 136
Query: 133 DMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
D++ +A AF++DG+ V + E + + AHCED L+R GAM+ GK+
Sbjct: 137 DIDGMAKAGALAFSEDGKSVMDVLLYVEGLKAVKDAGCIMFAHCEDKQLVRNGAMNAGKK 196
Query: 192 SAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEV 251
+ EL ++GI + E ARDI LA H+CH S K SV V+ K+ I VT EV
Sbjct: 197 AEELNLRGITNAVEDVITARDIFLAGETGAKLHLCHCSTKASVALVKMAKELGIDVTAEV 256
Query: 252 TPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIR 311
PHH + DEDI D+ +KMNPPLR +ED AL G+ + +++I+TDHAPH EEK
Sbjct: 257 CPHHFILSDEDIPGDDANYKMNPPLRSKEDIQALKEGLKNNVMEVISTDHAPHGEEEKKN 316
Query: 312 GIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFAD 371
+ K+ FGIVGSETAF+ YT+ V+T + +V+ MS N A+I + G LE AD
Sbjct: 317 SMSKAPFGIVGSETAFSLTYTELVQTGYLTPMQMVEKMSYNPARILGIEKGSLEPGKMAD 376
Query: 372 IVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
IV+ D +KE I+ +F SKG+NTP+ KV G + TI+ G + Y
Sbjct: 377 IVIADFDKEYEIDATKFYSKGKNTPFHGRKVCGKVMYTIAAGAVVY 422
>gi|20807969|ref|NP_623140.1| dihydroorotase [Thermoanaerobacter tengcongensis MB4]
gi|22001882|sp|Q8R9R6|PYRC_THETN Dihydroorotase (DHOase)
gi|20516541|gb|AAM24744.1| Dihydroorotase [Thermoanaerobacter tengcongensis MB4]
Length = 431
Score = 310 bits (794), Expect = 1e-82, Method: Composition-based stats.
Identities = 170/407 (41%), Positives = 245/407 (60%), Gaps = 2/407 (0%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVY 71
G +K DILI I+ I +NIDV+D ID + ++V GF+D H H R+PGF +KET+
Sbjct: 15 GGEEKADILINYGIIKGIDKNIDVSDAIVIDAEGKYVLPGFVDMHTHLRQPGFEEKETIR 74
Query: 72 TASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGREL 131
T + +AA GGFTTV MPN NP DS + + + + V++ +P GA+TK G E+
Sbjct: 75 TGTESAAAGGFTTVACMPNTNPPIDSEVVVEYVKAVAQREGVVKVLPIGAMTKGMKGEEI 134
Query: 132 SDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGK 190
++M + V A +DDG + SA +M M G + ++ HCED +L G M+ G
Sbjct: 135 TEMAKLKKAGVVALSDDGFPIMSAGIMKRVMTYGKMYDLLMITHCEDKTLSGEGVMNSGI 194
Query: 191 RSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
+ LG+KGIP E +AR+I+LA+A H+ H+S K SV +R K+ + +T E
Sbjct: 195 IATMLGLKGIPREAEEVMLARNIILAKATGAKLHIAHVSTKGSVELIRRAKEEGVSITAE 254
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
VTPHHL DE + + K+ PPLR RED ALI G+ DGTID IATDHAPHT ++K
Sbjct: 255 VTPHHLTRTDEAVYNYDTNTKVFPPLRTREDVEALIEGLKDGTIDAIATDHAPHTKDDKK 314
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
+ + FGI G ETAF+ + T ++T I +++ LV MS N A+I + G + + A
Sbjct: 315 VPYDMAPFGISGLETAFSVINTFLIQTGIITMKALVNYMSMNPARILGISNG-IRVGATA 373
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
DIV+++ +E T++ E+F SKG+NTPY K+ G+ TI G+I Y
Sbjct: 374 DIVIVNPHEEYTVDKEKFKSKGKNTPYHGMKLKGVVEYTIVEGQIRY 420
>gi|114566809|ref|YP_753963.1| Dihydroorotase [Syntrophomonas wolfei subsp. wolfei str.
Goettingen]
gi|114337744|gb|ABI68592.1| Dihydroorotase [Syntrophomonas wolfei subsp. wolfei str.
Goettingen]
Length = 431
Score = 309 bits (792), Expect = 2e-82, Method: Composition-based stats.
Identities = 166/397 (41%), Positives = 228/397 (57%), Gaps = 1/397 (0%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
D+L++D KI +D + ID + V GFID HVH REPGF KE + + +RAA
Sbjct: 22 DLLVEDGKIRSRGNALDDSGCEIIDASGKIVCPGFIDIHVHLREPGFEYKEDIASGTRAA 81
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDM-ED 136
A GGFTTV MPN PV D+ + E + ++ +P G+I+K++ G ELS++ E
Sbjct: 82 ACGGFTTVCCMPNTEPVIDNEAVVGFVREKARKVGIVNVLPVGSISKKQAGLELSEIAEL 141
Query: 137 IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELG 196
+ A +DDG+ V AN+M A+ +++HCED +L+ GG MHEG S G
Sbjct: 142 VTAGCVAISDDGKPVMKANIMRNALDYAKMFGLPVLSHCEDLNLVNGGLMHEGYYSTIYG 201
Query: 197 IKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHL 256
++GIP+ E +ARDI+LA H H+CH S S+ VR+ K + VTCEVTPHHL
Sbjct: 202 LRGIPAAAEEVMVARDIILARLTGGHLHICHASTAGSMALVRQAKAEGLNVTCEVTPHHL 261
Query: 257 LSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKS 316
DE I + K+NPPLR E AL +LDGT+D IATDHAPH E K E +
Sbjct: 262 TLSDEIIDGYDADTKVNPPLRSEEHLLALREALLDGTVDCIATDHAPHHFEAKDCEYELA 321
Query: 317 SFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVID 376
+ GI G ETA + K V+ + ++ +VKL + A + + G LEE ADI +ID
Sbjct: 322 ACGISGLETAIAVIMDKLVRPGLLDIKDMVKLFTSGPAGVMGIDKGSLEEGKSADITIID 381
Query: 377 LEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
E T++P F SKGRNTPY ++ G P +T+ NG
Sbjct: 382 SEIVKTVDPRTFKSKGRNTPYKGMELQGWPCMTLVNG 418
>gi|51892396|ref|YP_075087.1| dihydroorotase [Symbiobacterium thermophilum IAM 14863]
gi|51856085|dbj|BAD40243.1| dihydroorotase [Symbiobacterium thermophilum IAM 14863]
Length = 434
Score = 308 bits (790), Expect = 4e-82, Method: Composition-based stats.
Identities = 169/429 (39%), Positives = 246/429 (57%), Gaps = 6/429 (1%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENIDVTDENT-IDVKDRFVTAGFIDAHV 57
+L++ ++L NG + D+L+ D +I I E + V T I+ + V GFID HV
Sbjct: 4 LLIRGGRLLDPANGVDRVADVLVADGRIRAIGEGLPVPPGATVIEASGKVVAPGFIDVHV 63
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H R PG KE + T + AA RGGF V+ MPN PV DS + L++ + + R
Sbjct: 64 HLRVPGQEYKEDMRTGTAAAVRGGFVGVVCMPNTRPVIDSAPLVAHVLDLAGREGLCRVW 123
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P GAITK G EL+++ ++A A TDDG+ V A M +AM+ + + ++ HCE
Sbjct: 124 PAGAITKGSQGEELAEIGEMARAGAVAVTDDGKPVDRAETMRQAMIYARQFDLPVMDHCE 183
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D SL GGAMHEG+ S+ LG+KGIP+ E +ARDILLA H+ H+S++ SV
Sbjct: 184 DRSLSAGGAMHEGRVSSLLGLKGIPAAAEEVHVARDILLALETGARVHLQHLSSRRSVEL 243
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKED--NGMWKMNPPLRGREDRNALIAGVLDGTI 294
VR GK RVT E TPHH D+ + + + KMNPPLR DR A++ G+ DGTI
Sbjct: 244 VRWGKAQGARVTAEATPHHFTLTDQAVADMAYSPNTKMNPPLREEADRQAILEGLADGTI 303
Query: 295 DIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVA 354
D+IATDHAPH ++EK ++FGI G ETA + V+ + LE L+ ++S A
Sbjct: 304 DVIATDHAPHHVDEKDVEYPLAAFGITGLETAVGLALDRLVRPGLIRLEQLILMLSTRPA 363
Query: 355 KIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
++ N L E + ADI V+DL++ T++ +E SK RN+P+ + G P T+ G+
Sbjct: 364 RLINRTPPALREGAEADITVLDLDRTWTVSADEMASKSRNSPFIGWTLTGAPYATVVGGR 423
Query: 415 IAYIDKEEI 423
+ ++ + I
Sbjct: 424 LRMLEMKVI 432
>gi|154500490|ref|ZP_02038528.1| hypothetical protein BACCAP_04162 [Bacteroides capillosus ATCC
29799]
gi|150270721|gb|EDM98017.1| hypothetical protein BACCAP_04162 [Bacteroides capillosus ATCC
29799]
Length = 427
Score = 305 bits (782), Expect = 3e-81, Method: Composition-based stats.
Identities = 162/406 (39%), Positives = 242/406 (59%), Gaps = 2/406 (0%)
Query: 17 VDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
+DILI+D KI I +I D ID + V AG ID HVH REPGF KET+ T RA
Sbjct: 21 MDILIEDGKIAVIGSDIREPDAQVIDARGMVVCAGLIDMHVHLREPGFEYKETIETGCRA 80
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMED 136
AA GGFT + M N PV DS E + L+ + ++R P GA++K + G+EL+D
Sbjct: 81 AAAGGFTGIAPMANTRPVTDSPEQVAYILQKAEEAGLVRVYPIGAVSKGQKGQELTDAGA 140
Query: 137 IADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAEL 195
+ + A +DDG VQ+AN++ +A+++ + N +++HCED ++ A++EG+ S +L
Sbjct: 141 LREAGAVALSDDGVPVQNANLLRDALILAHRHNLTVLSHCEDADMVGNRAVNEGRISRQL 200
Query: 196 GIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
+ G P+I E Q+ RD +LAE H+CHIS +SV VR K+ +++TCE P +
Sbjct: 201 RLDGRPAIAEELQVMRDAMLAEETGAAVHICHISTAKSVAIVRRYKRKGVQITCETCPQY 260
Query: 256 LLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEK 315
+++I M ++NPPLR R D +I G+ DGTID IATDHAPH+ EEK R + +
Sbjct: 261 FSLTEDEILTKGTMARVNPPLRTRADVEGIIEGLKDGTIDAIATDHAPHSAEEKGRPLTE 320
Query: 316 SSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPY-GKLEENSFADIVV 374
+ G+VG ETA T T L +++ M+ N A I +P+ G+L D+V+
Sbjct: 321 APSGMVGLETALGVTLTALYHTGEMGLSDILRKMTMNPACILRIPHKGRLAIGGDGDLVI 380
Query: 375 IDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
+ +++ T++PE+F SKGRNTP+A ++ G T+ GKI Y D+
Sbjct: 381 FNPDEKWTVDPEKFHSKGRNTPFAGMELKGKVKYTVVGGKIVYQDQ 426
>gi|106894186|ref|ZP_01361307.1| Dihydroorotase multifunctional complex type [Clostridium sp.
OhILAs]
gi|106774407|gb|EAT30970.1| Dihydroorotase multifunctional complex type [Clostridium sp.
OhILAs]
Length = 428
Score = 302 bits (774), Expect = 3e-80, Method: Composition-based stats.
Identities = 167/418 (39%), Positives = 253/418 (60%), Gaps = 3/418 (0%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ + G + D+L+ ++ I +I E I V + +D K +V G ID HVH
Sbjct: 3 LLIKNGRVMDPETGMDQVQDVLVFNETIVEIGETIHVEADCIMDAKGYWVVPGLIDVHVH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
REPG+ KET+ T S++AA+GGFTT+ MPN NP DSVE + + + ++V+ +P
Sbjct: 63 LREPGYEHKETIKTGSKSAAKGGFTTICCMPNTNPAIDSVEVVRYIQKRSEEEAVVNVLP 122
Query: 119 YGAITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
G+ITK + G EL D++ +A+ V ++DG+ + ++ ++ +AM + + +HCED
Sbjct: 123 IGSITKGQAGEELVDIKGLAEVGVCGISEDGKTLINSALLKKAMKEAKACDIPVFSHCED 182
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
+ L+ GGAM+EG+R+ LGIKGI + E IAR+I+L H+CH+S KE V +
Sbjct: 183 HLLVEGGAMNEGQRAETLGIKGIGNDSEEVMIAREIILGRNTGVKLHICHVSIKEGVDLI 242
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ K+ + VT EV PHH DE +++D KMNPPLR +ED +A+ G+ +G IDII
Sbjct: 243 KTAKERGVWVTAEVCPHHFTLTDEIVEKDFTNAKMNPPLRAKEDVDAIKRGLAEGIIDII 302
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPHT EK K+ FGIVG ETA T+ V+T + + ++ M+ N AK+
Sbjct: 303 ATDHAPHTENEKDTEFHKAPFGIVGFETAVPLGITELVETGLLTPLQWIEKMTLNPAKLL 362
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
G+L+ N ADI +ID + I+ F SK +N+P+ KV G V TI G+I
Sbjct: 363 GSNKGRLQVNQCADITIIDPDAVYEIDIHSFASKSKNSPFHGRKVRGKVVHTIVGGRI 420
>gi|89210242|ref|ZP_01188633.1| Dihydroorotase multifunctional complex type [Halothermothrix orenii
H 168]
gi|89160102|gb|EAR79759.1| Dihydroorotase multifunctional complex type [Halothermothrix orenii
H 168]
Length = 434
Score = 300 bits (768), Expect = 1e-79, Method: Composition-based stats.
Identities = 172/429 (40%), Positives = 254/429 (59%), Gaps = 10/429 (2%)
Query: 2 LLKNCKILK--NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
LLKN ++ N + DILI+ I I + I + I ++ + V G ID H H
Sbjct: 5 LLKNGTVIDPVNNIRGQYDILIEGKHIINIKKEIKPENCQVIKLEGKVVIPGLIDMHTHL 64
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKN---DSVIRA 116
REPG+ +KET+ T AAA GGFTT+ MPN PV D+ T+ E IK+ ++V++
Sbjct: 65 REPGYEEKETIITGCEAAAAGGFTTIACMPNTRPVADNPATV----EYIKSKAREAVVKV 120
Query: 117 IPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHC 175
+P G+ITK G+EL+++ +A V +DDG V ++ +M AM + I++HC
Sbjct: 121 LPVGSITKNLEGKELAEIGFLARAGVCGLSDDGNPVMNSEIMRRAMEYARAFDLPIISHC 180
Query: 176 EDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVR 235
ED L+ G M+EG S LG+K IP+ E I+RDI+LA+ H+ H+S ++ V
Sbjct: 181 EDLDLVGDGVMNEGYYSTILGLKPIPAAAEEVMISRDIILADFTGARLHIDHLSTRKGVE 240
Query: 236 AVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTID 295
V K+ +RVT EVTPHHL+ D+ +K N ++NPPLR EDR AL G+ +G ID
Sbjct: 241 MVARAKEKGLRVTAEVTPHHLILTDKAVKGYNPNTRVNPPLRSSEDRAALRQGIKEGIID 300
Query: 296 IIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
+IATDHAPHT E+K+ + + GI G ETA + +Y + +KT S E LV+LM N ++
Sbjct: 301 VIATDHAPHTFEDKLGEYDYAENGISGLETALSLIYDRLIKTGEISWEDLVRLMVINPSE 360
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
I + ++ + ADI + D ++ +NPE F SKG+NTP+A+ ++ G V+TI +GKI
Sbjct: 361 IVGVKAEGIKRYARADITIFDPDRTWQVNPENFKSKGKNTPFADWELTGKVVMTIVDGKI 420
Query: 416 AYIDKEEIN 424
Y D+ N
Sbjct: 421 VYDDRSGNN 429
>gi|150391903|ref|YP_001321952.1| dihydroorotase, multifunctional complex type [Alkaliphilus
metalliredigens QYMF]
gi|149951765|gb|ABR50293.1| dihydroorotase, multifunctional complex type [Alkaliphilus
metalliredigens QYMF]
Length = 429
Score = 299 bits (766), Expect = 2e-79, Method: Composition-based stats.
Identities = 165/418 (39%), Positives = 249/418 (59%), Gaps = 3/418 (0%)
Query: 1 MLLKNCKILKNG-KFKKV-DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K + DIL+ ++KI ++ + I+ + ID K +V G ID HVH
Sbjct: 3 LLIKNGRVIDPATKLDAIKDILVLNEKIVEVQDEINQEADEIIDAKGYWVVPGLIDVHVH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
REPGF KET+ T S++AA GGFTT+ MPN PV DSVE + E K +V+ +P
Sbjct: 63 LREPGFEHKETIETGSKSAAMGGFTTICCMPNTQPVVDSVEIVQYIKEKTKRQAVVNVLP 122
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
G+ITK + G+EL D+E + + + ++DG+ V + ++ +AM N + +HCED
Sbjct: 123 IGSITKGQMGKELVDVEKLVESGICGISEDGKTVMDSALLKKAMEQAKAANIPVFSHCED 182
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
++L++GGAM+ GK++ LGIKG+ E IARDI+LA H+CH+S K V
Sbjct: 183 HTLVQGGAMNAGKKAEALGIKGLGRDAEEVIIARDIILARNTGVKLHLCHVSTKGGVELT 242
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
RE K+ VT EV PHH ++ +++D KMNPPLR ED +A+ G++DGTI++I
Sbjct: 243 REAKQRGENVTAEVCPHHFALTEDIVEKDFTNSKMNPPLRTGEDVDAIKQGLVDGTIEVI 302
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH +EK + ++ FGIVG ETA + T+ V T + + ++ M+ N AK+
Sbjct: 303 ATDHAPHHADEKNQEFHQAPFGIVGLETALSIGMTELVATKLLTPMSFIEKMTINPAKLL 362
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
+ G ++ ADI ++D E I+ F SK N+P+ KV G + TI G+I
Sbjct: 363 GIDKGTIQVGKIADITILDSNLEYEIDVNTFASKSNNSPFHGSKVKGKVMFTIVAGEI 420
>gi|76796898|ref|ZP_00779247.1| Dihydroorotase multifunctional complex type [Thermoanaerobacter
ethanolicus ATCC 33223]
gi|114843799|ref|ZP_01454259.1| dihydroorotase, multifunctional complex type [Thermoanaerobacter
ethanolicus X514]
gi|76587743|gb|EAO64166.1| Dihydroorotase multifunctional complex type [Thermoanaerobacter
ethanolicus ATCC 33223]
gi|114806123|gb|EAU57904.1| dihydroorotase, multifunctional complex type [Thermoanaerobacter
ethanolicus X514]
Length = 431
Score = 298 bits (764), Expect = 3e-79, Method: Composition-based stats.
Identities = 170/419 (40%), Positives = 249/419 (59%), Gaps = 3/419 (0%)
Query: 1 MLLKNCKILKN-GKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
M++KN ++ G DILI I+ I +NI V+D ID ++V GF+D H H
Sbjct: 3 MIIKNGTVIDGFGSEATADILIDYGIIKAIDKNIQVSDGIVIDATGKYVLPGFVDMHTHL 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
R+PGF +KET+ T + AAA GG+TTV MPN NP D+ + I + + V++ +P
Sbjct: 63 RQPGFEEKETIKTGTEAAATGGYTTVACMPNTNPPIDNEIVVEYVKSIAQREGVVKVLPI 122
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
GA+TK G E+++M + V A +DDG + SA +M M G + ++ HCED
Sbjct: 123 GAMTKGMKGEEITEMAKLKKAGVVALSDDGFPIMSAGLMKRIMTYGKMYDLLMITHCEDK 182
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
+L G M+ G S +G+KGIP E +AR+I+LA++ H+ HIS K SV +R
Sbjct: 183 ALSGEGVMNSGVISTMIGLKGIPREAEEVMLARNIILAKSTGVRLHIAHISTKGSVELIR 242
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
E K+ +++T EVTPH+L DE + + K PPLR RED ALI G+ DGTID IA
Sbjct: 243 EAKEKGVKITAEVTPHNLTLTDEAVYNYDTNTKAYPPLRTREDIEALIEGLKDGTIDAIA 302
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPHT ++K + ++FGI G ETAF+ + T V+T +++ LV MS N AKI
Sbjct: 303 TDHAPHTKDDKKVPYDMAAFGISGLETAFSVINTFLVQTGKITIKELVNYMSINPAKILG 362
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+ G ++ S ADIV++D +E ++ ++F SKG+NTP+ ++ G+ TI G+I Y
Sbjct: 363 ISSG-IKVGSIADIVIVDPYEEYVVDKDKFKSKGKNTPFHGMRLKGVVDCTIVEGEIKY 420
>gi|34391543|gb|AAN61168.1| dihydroorotase [Sporosarcina psychrophila]
Length = 285
Score = 298 bits (763), Expect = 4e-79, Method: Composition-based stats.
Identities = 147/282 (52%), Positives = 193/282 (68%), Gaps = 2/282 (0%)
Query: 2 LLKNCKILK-NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L++ ++L +G+ D+ + DKI +I + + V ID K + GFID HVH R
Sbjct: 4 LIQGVQMLNGDGELVTADVKVTGDKITEIGKQLPVEHAEVIDGKGLLLAPGFIDVHVHLR 63
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG KET+ + + AAA+GG+TT+ MPN PVPD+ E L ++I S+IR +PY
Sbjct: 64 EPGGEHKETIESGTLAAAKGGYTTICAMPNTRPVPDTKENLTFVNDLIAQKSLIRVLPYA 123
Query: 121 AITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+IT E G+E +++ ++ + FAFTDDG G+Q A +MYEAM +K+ IVAHCEDN+
Sbjct: 124 SITIREAGKERTNLAELKEHGAFAFTDDGVGIQQAGMMYEAMQEAAKIGMPIVAHCEDNT 183
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
LI GGAMHEGKR+ ELG+ GIPSI ES IARDILLAEAA HYHVCH+S KESVR +R+
Sbjct: 184 LIYGGAMHEGKRNKELGLPGIPSIAESVHIARDILLAEAAGAHYHVCHVSTKESVRVIRD 243
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGRED 281
KK + VT EV+PHHLL ++DI D+ WKMNPPLRG ED
Sbjct: 244 AKKAGVHVTAEVSPHHLLLSEDDIPGDDADWKMNPPLRGTED 285
>gi|125973469|ref|YP_001037379.1| dihydroorotase, multifunctional complex type [Clostridium
thermocellum ATCC 27405]
gi|125713694|gb|ABN52186.1| dihydroorotase, multifunctional complex type [Clostridium
thermocellum ATCC 27405]
Length = 426
Score = 298 bits (763), Expect = 5e-79, Method: Composition-based stats.
Identities = 158/405 (39%), Positives = 242/405 (59%), Gaps = 1/405 (0%)
Query: 17 VDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
+DIL++D I +I ++I++++ + I + + V G +DAH H R+PGF KE + T + +
Sbjct: 19 MDILVEDGIITEIGKDIEISNGDIIYAEGKLVLPGLVDAHCHLRDPGFEYKEDIETGTMS 78
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMED 136
AA GGFT++ MPN +PV D+ + + K D + P GAI+K + G ELS++ +
Sbjct: 79 AAMGGFTSIACMPNTDPVCDNKAVVKYIINKAKQDGYVNVYPIGAISKGQKGEELSEIGE 138
Query: 137 IA-DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAEL 195
+ A +DDG+ V+S+++M A+ S + A+++HCED L GG M+EG S +
Sbjct: 139 LKFAGAVAISDDGKPVKSSSLMKRALEYSSMFDIAVISHCEDLDLADGGVMNEGYWSTVM 198
Query: 196 GIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
G+KGIPS E +ARDI+L+E H+ H+S + SV +R KK ++VTCE PH+
Sbjct: 199 GLKGIPSAAEEIMVARDIILSEYTKVPIHIAHVSTELSVELIRNAKKRGVKVTCETCPHY 258
Query: 256 LLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEK 315
+ DE K+ N + K+NPPLR R D A+I G+ DGTIDIIATDHAPH +EK
Sbjct: 259 FVLTDEACKDFNTLAKVNPPLRTRRDVEAVIEGLKDGTIDIIATDHAPHHADEKNVEFNL 318
Query: 316 SSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVI 375
++ G+VG ETA T VK ++ LV+ M N +K+ + G LE ADI ++
Sbjct: 319 AANGMVGFETALPLAITYLVKPGHLTISQLVEKMCVNPSKLLGINKGTLETGRSADITIV 378
Query: 376 DLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
DL +E ++ +F SK +N+P+ K+NG T+ NG + +K
Sbjct: 379 DLNEEFVVDVNKFKSKSKNSPFHGFKLNGSVYYTLVNGNVVVREK 423
>gi|85860057|ref|YP_462259.1| dihydroorotase [Syntrophus aciditrophicus SB]
gi|85723148|gb|ABC78091.1| dihydroorotase [Syntrophus aciditrophicus SB]
Length = 426
Score = 296 bits (757), Expect = 2e-78, Method: Composition-based stats.
Identities = 157/405 (38%), Positives = 240/405 (59%), Gaps = 4/405 (0%)
Query: 16 KVDILIKDDKIEKISENIDVTDENT--IDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
++D+L+++ KI I+E + E+T +D+K + G +D H H REPG+ KET+ +
Sbjct: 20 QMDLLLENGKIAAIAEAVGSVPEDTRLLDLKGMILLPGLVDMHTHLREPGYEYKETIRSG 79
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSD 133
S AAA GGFT++ MPN PV D+ L+ K + P A+++ G+ L++
Sbjct: 80 SEAAAVGGFTSIACMPNTLPVNDNRTVTEYILKRAKECDTVHVYPVAAVSRNSEGKILAE 139
Query: 134 MEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRS 192
D+ + AF+DDG+ V ++ +M A+ S L++ I++HCED +L GG M+EGK S
Sbjct: 140 FGDLKEAGAIAFSDDGKPVMNSILMRRALEYASSLDRIIISHCEDLNLSAGGLMNEGKIS 199
Query: 193 AELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVT 252
ELG+ GIP++ E +ARD+LLAE + H+ H+S+ +VR +R+ KK +RVT E T
Sbjct: 200 TELGLPGIPTLAEDVMVARDLLLAEFSGAALHIAHVSSAGAVRMIRDAKKRGVRVTAETT 259
Query: 253 PHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRG 312
PH+ DE + N K++PPLR RED A+ G+ DGT+D I TDHAPH + +K
Sbjct: 260 PHYFTLTDEAVTNFNTNTKVSPPLRSREDLQAVREGLRDGTLDAIVTDHAPHALTDKEVE 319
Query: 313 IEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADI 372
E ++ GI G ETA L V + +L LV+ MS N AKI N+P G L + ADI
Sbjct: 320 FEYAANGISGLETALA-LSLTLVDDGLLTLSELVRKMSVNPAKILNIPKGTLRPGADADI 378
Query: 373 VVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
V++ K ++P + S+G+NTP+ + G ++T+ G+I Y
Sbjct: 379 TVLNPGKTWVVDPSNWRSQGKNTPFFGWTLKGKVIMTLVQGRIVY 423
>gi|57234049|ref|YP_181913.1| dihydroorotase [Dehalococcoides ethenogenes 195]
gi|57224497|gb|AAW39554.1| dihydroorotase, multifunctional complex type [Dehalococcoides
ethenogenes 195]
Length = 427
Score = 294 bits (752), Expect = 9e-78, Method: Composition-based stats.
Identities = 170/425 (40%), Positives = 246/425 (57%), Gaps = 10/425 (2%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENI--DVTDENTIDVKDRFVTAGFIDAH 56
+L+KN +I+ G K D+L+++ + I+ NI D DE ID + + V GFID H
Sbjct: 3 ILIKNGRIIDPAGGTDKVADLLLENGLVAGINSNIPSDKADE-VIDAEGKVVCPGFIDLH 61
Query: 57 VHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRA 116
VH REPGF KET+ + +AAA GGFTT+ MPN NP D++ ++ S IR
Sbjct: 62 VHLREPGFEGKETIESGCKAAAAGGFTTICPMPNTNPAADNLPVIDFVRNTAAKVSPIRV 121
Query: 117 IPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHC 175
+P AITK G+ELS M ++A+ V F+DDG V +++++ A+L ++ HC
Sbjct: 122 LPIAAITKGRKGQELSPMGELAEAGVAGFSDDGDYVSNSSMLLHALLYSRTFGLPVMEHC 181
Query: 176 EDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVR 235
E+ L GG M+EG + LG+KGIP E ++RDI LA+ + H+CHIS SV
Sbjct: 182 EEPCLAEGGVMNEGLLACRLGLKGIPDAAEEIALSRDIALAKESGGQLHLCHISTAGSVE 241
Query: 236 AVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTID 295
VR K I+V+ EVTPHHL + ++ N K+NPPLR + D ALI G+ DGTID
Sbjct: 242 LVRRAKAAGIQVSAEVTPHHLTLTEAEVSGYNTNAKVNPPLRTQSDIEALIKGLKDGTID 301
Query: 296 IIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IATDHAPHT +K+ ++ GI G ETAF L V + SL +L++ ++ +
Sbjct: 302 AIATDHAPHTANDKLCEFGLAANGISGLETAFASL-MGLVHSGSISLSLLIEKLTAGPRQ 360
Query: 356 IFNLPY---GKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISN 412
+ + G L+ S AD+V+ D ++E T++ F SKG+NTP ++ G TI+
Sbjct: 361 VLGEKHKNIGNLKPGSSADVVIFDPDEEWTVDTARFFSKGKNTPLEGRRLKGRVKTTIAC 420
Query: 413 GKIAY 417
G+IAY
Sbjct: 421 GRIAY 425
>gi|73748889|ref|YP_308128.1| dihydroorotase [Dehalococcoides sp. CBDB1]
gi|73660605|emb|CAI83212.1| dihydroorotase, multifunctional complex type [Dehalococcoides sp.
CBDB1]
Length = 428
Score = 293 bits (749), Expect = 2e-77, Method: Composition-based stats.
Identities = 170/424 (40%), Positives = 244/424 (57%), Gaps = 8/424 (1%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHV 57
+L+KN +I+ +G D+LI++ + IS++I E ID + V GFID HV
Sbjct: 3 ILIKNGRIIDPASGTDNVADLLIENGLVTGISKDISPEKTEKVIDATGKVVCPGFIDLHV 62
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H REPGF KET+ + +AAA GGFT++ MPN NP D + ++ S+IR +
Sbjct: 63 HLREPGFEGKETIESGCKAAAAGGFTSICPMPNTNPAADCLPVIDFIKNTATKVSLIRVL 122
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P AITK G+ELS M ++A+ V F+DDG V ++++ A+L + I+ HCE
Sbjct: 123 PIAAITKGRKGQELSPMGELAEAGVVGFSDDGDYVSGSSLLLNALLYSRTFDLPIMEHCE 182
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D L GG M+EG + LG+KGI + E + RDI LA+ + H+CHIS SV
Sbjct: 183 DACLAEGGLMNEGLLACRLGLKGITNATEEIAVNRDIALAKESGGRLHLCHISTAGSVEL 242
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
VR+ K IRV+ EVTPHHL + ++ N K+NPPLR + D ALIAG+ DGTID
Sbjct: 243 VRQAKAAGIRVSAEVTPHHLTLTEAEVNGYNTSAKVNPPLRTQTDIEALIAGLKDGTIDA 302
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPHT +K+ ++ GI G ETA L V + SL +L++ ++ ++
Sbjct: 303 IATDHAPHTRNDKLCEFGLAANGISGLETALASL-MGLVHSGKLSLSLLIEKLTLGPQQV 361
Query: 357 FNLPY---GKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
Y G L+ S AD+V+ D ++E T++ +F SKG+NTP K+ G TI+ G
Sbjct: 362 LGEKYQNIGNLKAGSCADVVIFDPDEEWTVDTAKFFSKGKNTPLEGRKLKGRVNTTIACG 421
Query: 414 KIAY 417
+I Y
Sbjct: 422 QIVY 425
>gi|156869403|gb|EDO62775.1| hypothetical protein CLOLEP_00364 [Clostridium leptum DSM 753]
Length = 424
Score = 291 bits (744), Expect = 7e-77, Method: Composition-based stats.
Identities = 159/409 (38%), Positives = 235/409 (57%), Gaps = 9/409 (2%)
Query: 15 KKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTAS 74
+++D+L ++ IEKI +NI + T+D + + G +D HVH R+PG + KE V+T
Sbjct: 20 ERLDLLCRNGVIEKIEKNIQDPADKTVDAQSLALLPGLVDMHVHLRDPGLTYKEDVFTGC 79
Query: 75 RAAARGGFTTVMTMPNLNPVPDS---VETLNKQLEIIKNDSVIRAIPYGAITKEEYGREL 131
RAAA GG T+++ MPN P DS VE L ++ E + R P ITK G EL
Sbjct: 80 RAAAAGGVTSLLAMPNTKPPMDSPALVEELLQRAE----SACCRVYPAVCITKGMKGEEL 135
Query: 132 SD-MEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGK 190
+ ME A TDDGR V+++ +M AM + L +V+HCED L +GG M+EG
Sbjct: 136 APFMELQKAGAVALTDDGRPVENSLLMARAMKEAASLGLRVVSHCEDLYLSQGGLMNEGA 195
Query: 191 RSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
S EL + G+P+ E+ AR+I LAE+ H+CH+S S +R+ KK ++VT E
Sbjct: 196 VSRELNVPGVPAASENAATAREIALAESYGVPIHICHVSTAVSAAMIRDAKKRGVQVTGE 255
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
PH+LL +E +++ N W+M+PPLR EDR AL+ + DGT+D IATDHAPH+ E+K
Sbjct: 256 TAPHYLLLTEEALRKKNADWRMSPPLRTDEDRKALLEALRDGTLDAIATDHAPHSEEDKA 315
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
++ G +G ETA + YT VKT +L L+ MS N A++ LP G L A
Sbjct: 316 -DFYRAPNGSIGMETALSACYTALVKTGYLTLPELIAKMSLNPARLLKLPGGTLRAGGPA 374
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
D + D + T++ + + +NTP+ ++G V+T+ G+I Y D
Sbjct: 375 DFALFDENRRWTVDRDRLHGRSKNTPFHGMSLSGKVVMTVCRGEIVYQD 423
>gi|78043256|ref|YP_360333.1| dihydroorotase [Carboxydothermus hydrogenoformans Z-2901]
gi|77995371|gb|ABB14270.1| dihydroorotase [Carboxydothermus hydrogenoformans Z-2901]
Length = 430
Score = 291 bits (744), Expect = 8e-77, Method: Composition-based stats.
Identities = 165/422 (39%), Positives = 248/422 (58%), Gaps = 7/422 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
ML+KN ++ ++GK +K+D+LI I +IS I+ +D ID++ +F+ G ID HVH
Sbjct: 3 MLIKNGNVVMVEDGKIRKMDVLIDKGIIVEISPEINRSDVEVIDIEGKFLIPGLIDMHVH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+R+PG++ KE +++ S AA GGFT V+ MPN +P PD+ + E K+ S+ I
Sbjct: 63 FRDPGYTHKEDIHSGSNAALAGGFTGVLMMPNTDPPPDNATVIYYWKE--KSKSIPLNIL 120
Query: 119 Y-GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
+ G ITK G+ELS ++ + A TDDG V V AM + L+ ++ H E
Sbjct: 121 FSGCITKNRAGKELSKFYELKEAGAVAITDDGNWVADGAVFRHAMEYAAALDLLVITHPE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
+ ++ G ++EG S LG++GIP E+ I RDI +A+ HV H+S E VR
Sbjct: 181 EPTIANRGVINEGYWSTVLGLRGIPKAAENIAIYRDIEIAKMTGAKLHVAHLSTAEGVRL 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
V KK ++VT EVTPHHL+ DE + + K+NPPLR E++ AL+ G+L+G ID+
Sbjct: 241 VAAAKKLGLKVTAEVTPHHLVLTDEALAGYDTNLKVNPPLREAEEQKALLKGLLEGVIDV 300
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPH EK + FGI G ETAF LYT+ V +LE L+ M+ N AKI
Sbjct: 301 IATDHAPHASYEKNVEFNDAPFGIEGLETAFPVLYTELVLKKKITLEKLLLKMTVNPAKI 360
Query: 357 FNLP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
LP G +++ ++A++ VID + + ++ E + K +N P+ + G PV+T+ G +
Sbjct: 361 LQLPKQGDIKKGNYANLTVIDPKLTLKVSEELLVGKSKNNPFLGRTLTGWPVMTVYQGIV 420
Query: 416 AY 417
AY
Sbjct: 421 AY 422
>gi|27262402|gb|AAN87482.1| Dihydroorotase [Heliobacillus mobilis]
Length = 433
Score = 288 bits (738), Expect = 4e-76, Method: Composition-based stats.
Identities = 169/430 (39%), Positives = 247/430 (57%), Gaps = 12/430 (2%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKD---RFVTAGFIDA 55
+L+K +++ NG + D+ I++ I+ + + + V D + V G ID
Sbjct: 3 LLIKGGRVIDPANGVDQIADVYIENGVIKAVGNSTGEAASKQVQVIDATGKLVIPGLIDI 62
Query: 56 HVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDS---VETLNKQLEIIKNDS 112
H H REPG KET+ +RAAARGGFT V MPN NPV DS VE L + + +
Sbjct: 63 HCHLREPGGEAKETIAAGTRAAARGGFTAVCAMPNTNPVCDSQTGVEFLKARAQATGS-- 120
Query: 113 VIRAIPYGAITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAI 171
+R P GAITK G+EL++M D+A AF+DDG+ V +++M AM + K I
Sbjct: 121 -VRVYPIGAITKGSSGQELAEMADMAACGAVAFSDDGKPVPRSDIMRLAMSYAQMVGKVI 179
Query: 172 VAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAK 231
++HCED L + G MHEG S LG++GIP+ E +AR+ILLAE+ H+ H+S
Sbjct: 180 ISHCEDPELAKDGVMHEGYWSTVLGLRGIPAAAEEIMVAREILLAESVGAPVHIAHVSTA 239
Query: 232 ESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLD 291
SV +R+ ++ + VT EV PHHL D ++ + K+NPPLR +DR AL G+ +
Sbjct: 240 GSVELIRQARQRGVDVTGEVCPHHLALTDRAVEGFDTSTKVNPPLRADKDREALKQGLKE 299
Query: 292 GTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSE 351
G + I+ATDHAPHT EEK R + FGI G ETA+ + + ++T ++ LV +++
Sbjct: 300 GVLTILATDHAPHTAEEKAREYNYAPFGISGLETAWPLYWKELIETGCLTVNELVAMLTV 359
Query: 352 NVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTIS 411
N A+ L G L S AD+ VID E++ T+ E + SKGRNTP+ + PV TI
Sbjct: 360 NPARRLGLAGGTLTVGSPADVTVIDTERKETVTLEGWQSKGRNTPFVGWTLQSWPVTTIV 419
Query: 412 NGKIAYIDKE 421
G++ ID++
Sbjct: 420 GGRVVMIDRQ 429
>gi|116624589|ref|YP_826745.1| dihydroorotase, multifunctional complex type [Solibacter usitatus
Ellin6076]
gi|116227751|gb|ABJ86460.1| dihydroorotase, multifunctional complex type [Solibacter usitatus
Ellin6076]
Length = 430
Score = 288 bits (736), Expect = 6e-76, Method: Composition-based stats.
Identities = 154/419 (36%), Positives = 222/419 (52%), Gaps = 9/419 (2%)
Query: 8 ILKNGKF--------KKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
+++NG+ + D+ I D +I ++ N+ D V GFID HVH
Sbjct: 4 VIRNGRVIDPASNTDRVADVFIVDGRIAGVAPNLSSPKAEVFDATGMIVAPGFIDMHVHL 63
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPGF ET+ + SRAAA GGFT++ MPN PV DS + +E ++ + + P
Sbjct: 64 REPGFEHAETIESGSRAAAAGGFTSICCMPNTKPVNDSAMVTSYIVEQARSKAAVNVFPI 123
Query: 120 GAITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
GAITK G EL+ + + A A +DDG V +A VM AM + I+ HCED
Sbjct: 124 GAITKGSAGEELAAIGAMKAAGAVAISDDGLPVMNARVMRRAMEFARSYDLPIIQHCEDL 183
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
+L GG MHEG S G++GIP+ E +ARD++LA+ YHV HIS + +V V
Sbjct: 184 NLSAGGDMHEGANSVRWGLRGIPAASEDVMVARDLVLAQLTGARYHVAHISTRNAVAMVE 243
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
G+ + + VTCE TPHH D D+ + +KM PPLR R+A+I G++ GTI IA
Sbjct: 244 YGRSHGLPVTCETTPHHFGLADADMAPYDSNYKMKPPLRSCGHRDAIIEGLIAGTISAIA 303
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH EK++ E+ FGI+G ETA + V +L L++L + +
Sbjct: 304 TDHAPHPGSEKMQEFERCPFGIIGLETALALALEELVAPGKITLARLIELFTTGPESVMR 363
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L G L + D+ V E T + + S+ RN+P+ +G P+ TI NG + +
Sbjct: 364 LGRGTLTPGAPGDVTVFSPTVEWTYDVNQSASRSRNSPFHARTFHGGPMATIVNGGLKW 422
>gi|83589731|ref|YP_429740.1| dihydroorotase, multifunctional complex type [Moorella
thermoacetica ATCC 39073]
gi|83572645|gb|ABC19197.1| dihydroorotase, multifunctional complex type [Moorella
thermoacetica ATCC 39073]
Length = 431
Score = 288 bits (736), Expect = 7e-76, Method: Composition-based stats.
Identities = 160/402 (39%), Positives = 234/402 (58%), Gaps = 6/402 (1%)
Query: 18 DILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
DILI+ +KI ++ N++ ID VT G ID HVH REPG+ +KET+ + +RA
Sbjct: 22 DILIEGEKITTLAANLEAPAGARVIDAGGMIVTPGLIDMHVHLREPGYEQKETIASGTRA 81
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMED 136
AA GGFT V M N NPV DS + E + + V+R P GA++K G+E++++ D
Sbjct: 82 AAAGGFTAVACMANTNPVADSASVIYFIKEKARQEGVVRVYPVGALSKGLEGKEIAEIGD 141
Query: 137 IADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAEL 195
+A A +DDGR V +A VM A+ N +++HCED +L G MHEG + L
Sbjct: 142 LAAAGAVAISDDGRPVMNALVMRHALEYAKMFNLPVISHCEDEALANDGLMHEGLVATIL 201
Query: 196 GIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
G++GIP+ E +ARD++LAE H+ H+S SVR ++E + +RVT E TPHH
Sbjct: 202 GLRGIPAAAEEVMVARDLILAELTGGRLHLAHVSTAGSVRLLKEARARGVRVTAEATPHH 261
Query: 256 LLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEK 315
L D ++ + K+NPPLR D A+ A + G ID+IA+DHAPH E+K +
Sbjct: 262 LCLTDMLVQSYDTSTKVNPPLRPAGDVAAVAAALAAGDIDVIASDHAPHADEDKDVEYDY 321
Query: 316 SSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVI 375
+ FG+VG ETA + T+ + + + +K + N A+I N+P G L AD+ +I
Sbjct: 322 APFGMVGLETAVPLVVTELILPGKLTWQQAIKSWTANPARILNIPGGSLVPGGVADVTII 381
Query: 376 --DLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
D+EKE+ +N EF S+G N+P K+ G PVLTI G++
Sbjct: 382 DPDMEKEVDVN--EFYSRGHNSPLQGRKLKGWPVLTIVGGRV 421
>gi|121535610|ref|ZP_01667416.1| dihydroorotase, multifunctional complex type [Thermosinus
carboxydivorans Nor1]
gi|121305780|gb|EAX46716.1| dihydroorotase, multifunctional complex type [Thermosinus
carboxydivorans Nor1]
Length = 429
Score = 287 bits (735), Expect = 8e-76, Method: Composition-based stats.
Identities = 162/418 (38%), Positives = 235/418 (56%), Gaps = 3/418 (0%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+LLKN +++ +G DILI + KI I E + + V GF+D H H
Sbjct: 3 LLLKNGRVINPADGTDTIKDILIAEGKIAAIGEELSADGAECFNAAGLVVAPGFVDMHTH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
REPG KE V + + AAA GGFTT+ MPN PV D+ + ++ + + ++
Sbjct: 63 LREPGLEAKEDVVSGTNAAAAGGFTTIACMPNTKPVVDNAILVAGLIQRAQVEGIVNLKV 122
Query: 119 YGAITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
GA++K + G+EL+++ D I A +DDG V SA ++ A+ +K I++H ED
Sbjct: 123 IGALSKGQEGKELAEIGDMILAGAVAISDDGHYVDSARLLKTALEYTGMFDKPIISHAED 182
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
SL+ G MHEG SA LG+KG P++ E +ARDI+LAE H+ H+S K +V +
Sbjct: 183 ESLVSDGYMHEGAVSAMLGMKGRPAVAEDIAVARDIMLAEYVGAPIHIAHVSTKGAVELI 242
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R+ K ++VT EVTPHHL DE +K + K+NPPLR +E ALI GV DGTID I
Sbjct: 243 RQAKNRGVKVTAEVTPHHLSLTDEAVKGFDTATKVNPPLRSQEHVAALIEGVKDGTIDAI 302
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH EEK + G G ETA + T T SL +++LM+ N A+I
Sbjct: 303 ATDHAPHAYEEKDMEYRYAPSGFAGLETALGVVLTALYHTGQLSLMEIIRLMAYNPARIL 362
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
L G + AD+ + D + + ++ ++F +KG++TP+ +K+ G V TI GKI
Sbjct: 363 GLDAGVIRVGGAADLTIFDPDLDWIVDSKKFYTKGKHTPFEGKKLKGKAVATIVGGKI 420
>gi|94971175|ref|YP_593223.1| dihydroorotase, multifunctional complex type [Acidobacteria
bacterium Ellin345]
gi|94553225|gb|ABF43149.1| dihydroorotase, multifunctional complex type [Acidobacteria
bacterium Ellin345]
Length = 429
Score = 287 bits (735), Expect = 9e-76, Method: Composition-based stats.
Identities = 161/408 (39%), Positives = 233/408 (57%), Gaps = 5/408 (1%)
Query: 15 KKVDILIKDDKIEKISE--NIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYT 72
+ +D+L+++ ++ I+E I E D V GFID HVH REPG + KET+ +
Sbjct: 22 RPMDVLLREGRVAAITEPGGIKSEYEEEFDANHLVVAPGFIDLHVHLREPGQAHKETIAS 81
Query: 73 ASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELS 132
+R+AA GGFT+V MPN +PV D+ ET L+ + +V+ P A T G +L+
Sbjct: 82 GTRSAAAGGFTSVCAMPNTSPVNDTPETTTWMLQPDRG-AVVNVFPIAAATIGSNGEKLT 140
Query: 133 DMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
+ D+ A +DDG+ + N+M EA+ ++L +V H ED + GG M+ G
Sbjct: 141 NFRDLQRAGAVAISDDGKPILDDNLMREALRTAARLEMPVVQHAEDPRMHPGGCMNYGVT 200
Query: 192 SAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEV 251
S LG++GIP+ E++ + RDI L + H HV HIS E++ AVR KK N+RVT EV
Sbjct: 201 SLRLGLRGIPNASEASVVLRDIRLTRESRAHLHVAHISTAEALDAVRRAKKENLRVTAEV 260
Query: 252 TPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIR 311
TPHH DE+I + +KMNPPLR DR+A+IAG+ DGT+D IATDHAPH EK +
Sbjct: 261 TPHHFTLLDENIGHYDTAYKMNPPLRANPDRDAMIAGLKDGTLDCIATDHAPHAYHEKEQ 320
Query: 312 GIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPY-GKLEENSFA 370
+++ FGI+G ETA T K L +V+LMS + A++F L + G L S A
Sbjct: 321 EFDRAPFGIIGLETALPLAITVLHKHFEIPLTRIVQLMSTSPARLFQLMHRGSLAVGSHA 380
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYI 418
D+VV D + + + SK +NTP+ G + TI G+ Y+
Sbjct: 381 DVVVFDPKMKWKFEAAKGHSKSKNTPFDGWDFMGKVMATIVGGRPVYL 428
>gi|118727644|ref|ZP_01576238.1| dihydroorotase, multifunctional complex type [Clostridium
cellulolyticum H10]
gi|118662975|gb|EAV69642.1| dihydroorotase, multifunctional complex type [Clostridium
cellulolyticum H10]
Length = 428
Score = 286 bits (732), Expect = 2e-75, Method: Composition-based stats.
Identities = 161/416 (38%), Positives = 240/416 (57%), Gaps = 3/416 (0%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +L K G + DIL D I ++ ID ID +VT G +DAH H
Sbjct: 3 LLIKNGHVLDVKTGLDRVTDILAVDGIIHEVGSKIDEAGCEVIDATGLYVTPGLVDAHCH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
R+PG+ KE + + +R+AA+GGFT+V MPN NPV D+ + + K D + P
Sbjct: 63 LRDPGYEYKEDIESGTRSAAKGGFTSVACMPNTNPVLDNEAMVKYVINKAKTDGFLNVFP 122
Query: 119 YGAITKEEYGRELSDMEDIA-DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
GA++K G ELS++ ++ A +DDGR V ++++M +AM S + I++HCED
Sbjct: 123 IGALSKGLKGEELSEIGELKFAGAVALSDDGRPVGNSSLMKKAMQYASMFDITIISHCED 182
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L+ G M+EG +S+ LG+KG P+ E IARD++LAE H+ H+S + V +
Sbjct: 183 LDLVDEGLMNEGYQSSILGLKGNPAPAEEVMIARDLILAEYTKATIHIAHVSTELGVDLI 242
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K+ ++VT E PH+ D + N K+NPPLR ++D +A+I G+ DGTIDII
Sbjct: 243 RNAKRRGVKVTAETCPHYFTLTDNACEGFNTNAKVNPPLRTQKDVDAIIQGLKDGTIDII 302
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
+TDHAPH ++EK + ++ G+VG ETAF T VK SL+ LV MS N +++
Sbjct: 303 STDHAPHHIDEKNVEFKIAANGMVGFETAFPLAVTYLVKPGHLSLKELVYKMSFNPSQML 362
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
L G +E AD+++ DL +E +N EF SK +N+P+ + G P TI G
Sbjct: 363 GLNKGTIEVGKLADLIIFDLNEEYKVNITEFESKSKNSPFNGLLLYGQPQYTIVGG 418
>gi|139439776|ref|ZP_01773167.1| Hypothetical protein COLAER_02198 [Collinsella aerofaciens ATCC
25986]
gi|133774926|gb|EBA38746.1| Hypothetical protein COLAER_02198 [Collinsella aerofaciens ATCC
25986]
Length = 429
Score = 286 bits (731), Expect = 3e-75, Method: Composition-based stats.
Identities = 156/409 (38%), Positives = 228/409 (55%), Gaps = 10/409 (2%)
Query: 17 VDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
VD+LI DKI ++ EN+ V D+ +++ G +D HVH REPG+ KE + + +RA
Sbjct: 21 VDVLIDSDKIAEVGENLAVEGAEVRDLSGKYLVPGLVDMHVHLREPGYEVKEDIESGTRA 80
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSV----IRAIPYGAITKEEYGRELS 132
AA+GGFT V MPN +PV D+ +E +K+ + R P GA+T+ G +S
Sbjct: 81 AAKGGFTGVCAMPNTDPVTDN----GTVVEFVKSRAAEVGHCRVYPSGAMTRGLKGEAMS 136
Query: 133 DMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
+M D +A AFTDDGRGVQ A ++ M G K ++HC+D L+ G ++EGK
Sbjct: 137 EMGDMVAHGAVAFTDDGRGVQGAGMLRRCMDYGKMFGKVFMSHCQDEDLVGHGQINEGKV 196
Query: 192 SAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEV 251
S L ++G P+ E QIARDI +A+ H+ HIS + VR GK ++VTCE
Sbjct: 197 STRLALEGWPAAGEELQIARDIEIAKLTGAKLHIQHISTAHGLEIVRAGKAAGVQVTCEA 256
Query: 252 TPHHLLSCDEDIKED-NGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
TPHH+ + D+ E N K+NPPLR ED A+ GV+DGT+D I TDHAPHT EK
Sbjct: 257 TPHHMFLTENDLDETYNTSLKVNPPLRTEEDAEAIRQGVIDGTVDAIVTDHAPHTPWEKA 316
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
R E + FG++G ET+ + + T+ V T S+ +V+LM+ +I L +++ S A
Sbjct: 317 REFELAPFGMIGLETSLSLVLTELVNTGKMSMGRMVELMAIKPREILGLDQVQVKAGSVA 376
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
D+ V D T+ + + S+ N+ +A + G GK D
Sbjct: 377 DLTVFDPSATWTVGEDGYESRAENSGFAGRTLTGRATDVFVGGKQTLAD 425
>gi|88607405|ref|YP_504862.1| dihydroorotase, multifunctional complex type [Anaplasma
phagocytophilum HZ]
gi|88598468|gb|ABD43938.1| dihydroorotase, multifunctional complex type [Anaplasma
phagocytophilum HZ]
Length = 447
Score = 284 bits (727), Expect = 7e-75, Method: Composition-based stats.
Identities = 168/380 (44%), Positives = 222/380 (58%), Gaps = 7/380 (1%)
Query: 41 IDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVET 100
+D + G +D HVH REPG KETV T SRAAA GG TTV+ PN P ++V
Sbjct: 69 VDCNGHVLMPGIVDLHVHLREPGGEHKETVDTGSRAAAAGGVTTVVCQPNTIPRLENV-L 127
Query: 101 LNKQLEIIKNDSVIRAIP-YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMY 158
+ K L++ +S I YGA+TK + EL DM + D FTDDG V +A M
Sbjct: 128 VAKYLKMRALESSCVNIEFYGAVTKSD--GELCDMASLKDAGALGFTDDGLPVMNALYMK 185
Query: 159 EAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDI-LLAE 217
A L+ + H ED +L GG ++EG S ELG+KGIP I ES ++RDI LL E
Sbjct: 186 RAFEYAQDLDVVVAQHAEDCNLSDGGCINEGLVSRELGLKGIPDISESIMVSRDIQLLRE 245
Query: 218 AANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLR 277
HYHV HIS K+++ VR K+ +RVTCEVTPHH L + + E M KMNPPLR
Sbjct: 246 VPGAHYHVLHISTKKALDIVRAAKREGLRVTCEVTPHHFLLNESAVLEHGTMAKMNPPLR 305
Query: 278 GREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKT 337
EDR ++I+G+ DGTID IATDHAPH +EK R I +FGIVG ET +
Sbjct: 306 TEEDRLSMISGLEDGTIDCIATDHAPHAAQEKTRPISCCAFGIVGLETLLPLSLELYHNA 365
Query: 338 DIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPY 397
+ +++L KL S+ A+I LP GK+ + AD+V+ DLE TI+ +F SK +N+P+
Sbjct: 366 GMSLMDVLSKLTSKP-AEIVRLPRGKIAKGLVADLVIFDLEHVWTIDTAKFSSKSKNSPF 424
Query: 398 ANEKVNGIPVLTISNGKIAY 417
KV G + T+ +GK Y
Sbjct: 425 QGRKVKGKVLRTVVSGKTVY 444
>gi|145955299|ref|ZP_01804303.1| hypothetical protein CdifQ_04001720 [Clostridium difficile
QCD-32g58]
Length = 421
Score = 283 bits (725), Expect = 1e-74, Method: Composition-based stats.
Identities = 172/422 (40%), Positives = 253/422 (59%), Gaps = 9/422 (2%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDE--NTIDVKDRFVTAGFIDAH 56
+L+KN +++ K+ + + +D++IK++KI KI + D +DE ID V G +D H
Sbjct: 2 ILIKNGRVIDPKSQRDENIDLIIKENKIYKIGK-FDESDEYEKIIDASGNVVAPGLVDVH 60
Query: 57 VHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRA 116
VH+R+PGF+ KE + + +++AARGGFTTV+ M N NP+ D+ +T N E KN + I
Sbjct: 61 VHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNEDTFNYVKEKSKN-ACINV 119
Query: 117 IPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHC 175
+ AITK G+EL DME + V FTDDG + +N++ EAM+ +L+ + H
Sbjct: 120 LQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNLIMEAMIKAKELDVPLSFHE 179
Query: 176 EDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVR 235
ED SL+ ++ GK ++ELG+KG S+ E +ARD +LA + HIS+ SV
Sbjct: 180 EDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCMLALKTGAKVDIQHISSGVSVD 239
Query: 236 AVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTID 295
VR K V E +PHH +ED+ E KMNPPLR + DR+ +I G+ DGTI+
Sbjct: 240 MVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKMNPPLRSKWDRDKIIEGLNDGTIE 299
Query: 296 IIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IIATDHAPH+ EEK R K+ GI+G ET+ T V + S+ L++ MS N AK
Sbjct: 300 IIATDHAPHSKEEKDREFIKAPSGIIGLETSLALGITNLVHKNHLSMMQLIEKMSINPAK 359
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
++NL G +EE + ADIV+ + E+E T+ E F+SK N+P+ + + G TI NG+I
Sbjct: 360 LYNLNIGFIEEGAVADIVIFNPEEEWTV--ESFVSKADNSPFKGKSLYGKVNYTICNGEI 417
Query: 416 AY 417
Y
Sbjct: 418 VY 419
>gi|126699130|ref|YP_001088027.1| dihydroorotase [Clostridium difficile 630]
gi|115250567|emb|CAJ68391.1| dihydroorotase [Clostridium difficile 630]
Length = 421
Score = 283 bits (724), Expect = 1e-74, Method: Composition-based stats.
Identities = 172/422 (40%), Positives = 253/422 (59%), Gaps = 9/422 (2%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDE--NTIDVKDRFVTAGFIDAH 56
+L+KN +++ K+ + + +D++IK++KI KI + D +DE ID V G +D H
Sbjct: 2 ILIKNGRVIDPKSQRDENIDLIIKENKIYKIGK-FDESDEYEKIIDASGNVVAPGLVDVH 60
Query: 57 VHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRA 116
VH+R+PGF+ KE + + +++AARGGFTTV+ M N NP+ D+ +T N E KN + I
Sbjct: 61 VHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNEDTFNYVKEKSKN-ACINV 119
Query: 117 IPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHC 175
+ AITK G+EL DME + V FTDDG + +N++ EAM+ +L+ + H
Sbjct: 120 LQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNLIMEAMIKAKELDVPLSFHE 179
Query: 176 EDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVR 235
ED SL+ ++ GK ++ELG+KG S+ E +ARD +LA + HIS+ SV
Sbjct: 180 EDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCMLALKTGAKVDIQHISSGVSVD 239
Query: 236 AVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTID 295
VR K V E +PHH +ED+ E KMNPPLR + DR+ +I G+ DGTI+
Sbjct: 240 MVRFAKYLGATVVAEASPHHFTLTEEDVLEFGTNAKMNPPLRSKWDRDKIIEGLNDGTIE 299
Query: 296 IIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IIATDHAPH+ EEK R K+ GI+G ET+ T V + S+ L++ MS N AK
Sbjct: 300 IIATDHAPHSKEEKDREFIKAPSGIIGLETSLALGITNLVHKNHLSMMQLIEKMSINPAK 359
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
++NL G +EE + ADIV+ + E+E T+ E F+SK N+P+ + + G TI NG+I
Sbjct: 360 LYNLNIGFIEEGAVADIVIFNPEEEWTV--ESFVSKADNSPFKGKSLYGKVNYTICNGEI 417
Query: 416 AY 417
Y
Sbjct: 418 VY 419
>gi|73536332|pdb|1XRF|A Chain A, The Crystal Structure Of A Novel, Latent Dihydroorotase
From Aquifex Aeolicus At 1.7 A Resolution
gi|73536333|pdb|1XRT|A Chain A, The Crystal Structure Of A Novel, Latent Dihydroorotase
From Aquifex Aeolicus At 1.7 A Resolution
gi|73536334|pdb|1XRT|B Chain B, The Crystal Structure Of A Novel, Latent Dihydroorotase
From Aquifex Aeolicus At 1.7 A Resolution
Length = 467
Score = 282 bits (722), Expect = 3e-74, Method: Composition-based stats.
Identities = 166/406 (40%), Positives = 238/406 (58%), Gaps = 10/406 (2%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
DIL+++ KI+KI +NI V + ID K V GFID HVH R+PG + KE + + SR A
Sbjct: 68 DILVENGKIKKIDKNILVPEAEIIDAKGLIVCPGFIDIHVHLRDPGQTYKEDIESGSRCA 127
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI 137
GGFTT++ MPN NP D+ +N L+ K+ + R +P G ITK G+E++D +
Sbjct: 128 VAGGFTTIVCMPNTNPPIDNTTVVNYILQKSKSVGLCRVLPTGTITKGRKGKEIADFYSL 187
Query: 138 ADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELG 196
+ AFTDDG V ++VM +A+ + S+L I+ HCED+ L G ++EG+ SA LG
Sbjct: 188 KEAGCVAFTDDGSPVMDSSVMRKALELASQLGVPIMDHCEDDKLAYG-VINEGEVSALLG 246
Query: 197 IKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHL 256
+ E QIARD +LA+ H H+ H+S K S+ + K+ +++TCEV P+HL
Sbjct: 247 LSSRAPEAEEIQIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHL 306
Query: 257 LSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKS 316
L + ++ ++NPPLR +EDR ALI GV G ID ATDHAPH EK +E +
Sbjct: 307 LFTEREVLNSGANARVNPPLRKKEDRLALIEGVKRGIIDCFATDHAPHQTFEK-ELVEFA 365
Query: 317 SFGIVGSETAFT---QLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
GI+G +TA +LY K I SL+ L+++ + N A+I + G L+ S ADI
Sbjct: 366 MPGIIGLQTALPSALELYRK----GIISLKKLIEMFTINPARIIGVDLGTLKLGSPADIT 421
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
+ D KE +N E LSK RNTP + + G + TI +GK+ Y D
Sbjct: 422 IFDPNKEWILNEETNLSKSRNTPLWGKVLKGKVIYTIKDGKMVYKD 467
>gi|108762395|ref|YP_631705.1| dihydroorotase, multifunctional complex type [Myxococcus xanthus DK
1622]
gi|108466275|gb|ABF91460.1| dihydroorotase, multifunctional complex type [Myxococcus xanthus DK
1622]
Length = 437
Score = 282 bits (722), Expect = 3e-74, Method: Composition-based stats.
Identities = 162/417 (38%), Positives = 232/417 (55%), Gaps = 5/417 (1%)
Query: 10 KNGKFKKVDILIKDDKIEKISENI--DVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKK 67
+NG D+L++D K+ ++S + + +D ++V GFID HVH REPG K
Sbjct: 16 RNGVDGVRDVLVRDGKVVEVSVTLLPVPSSAEVVDATGKWVLPGFIDLHVHLREPGEEGK 75
Query: 68 ETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEY 127
ETV T RAA GGFT V+ MPN V D+ L + + P GAITK
Sbjct: 76 ETVLTGCRAAVAGGFTAVVAMPNTKVVNDNAMVTELVLNRARAAGLCHVYPAGAITKGLK 135
Query: 128 GRELSDM-EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAM 186
G EL++M E ++ A TDDGR V +A++M + ++ + ++ H ED +L GGAM
Sbjct: 136 GEELAEMGELVSAGCVAITDDGRPVMNASLMRRTLQYATQFDVPVMVHEEDLTLSAGGAM 195
Query: 187 HEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIR 246
HEG S LG++GIP+ E +ARD++L E HV H+S + SVR +RE K++ +R
Sbjct: 196 HEGTTSTRLGLRGIPASAEVAMVARDLVLLEETKGRLHVAHVSCEGSVRLIREAKRSGLR 255
Query: 247 VTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTM 306
VTCEV PHH + D + + + KM PPLR D AL ++DGT+D IATDHAPH +
Sbjct: 256 VTCEVAPHHFILDDRAVGDYDTHAKMAPPLRADTDVQALREALVDGTVDAIATDHAPHGV 315
Query: 307 EEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEE 366
+K EK GIVG ETA L + V + + V+L++ AK F LP G L
Sbjct: 316 LDKQVEFEKGINGIVGLETALG-LTLELVHAGVLTANRAVELLTHGPAKAFGLPGGHLAP 374
Query: 367 NSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKEEI 423
+ AD+ V+D + E T++ +F S+ RNTP+ K G + T G + DK ++
Sbjct: 375 GAPADVTVVDPDAEWTVDAHQFHSRSRNTPFHGRKQKGRVIQTWVAGHKVF-DKGQV 430
>gi|95929149|ref|ZP_01311893.1| dihydroorotase, multifunctional complex type [Desulfuromonas
acetoxidans DSM 684]
gi|95134647|gb|EAT16302.1| dihydroorotase, multifunctional complex type [Desulfuromonas
acetoxidans DSM 684]
Length = 426
Score = 282 bits (721), Expect = 3e-74, Method: Composition-based stats.
Identities = 152/409 (37%), Positives = 233/409 (56%), Gaps = 6/409 (1%)
Query: 11 NGKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHVHWREPGFSKKET 69
+G+F D++++D I ++ EN+ D + ID VT G ID HVH R+PGF KE
Sbjct: 18 DGRF---DLIVEDGCIVELGENLPAEDADEVIDADGLLVTPGLIDIHVHLRDPGFEYKED 74
Query: 70 VYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR 129
+ + +R+AA GGFT+V MPN PV D+ T + + + P ITK + G
Sbjct: 75 IVSGTRSAAAGGFTSVACMPNTKPVNDNKATTLYMINKAQLEGFANVFPICTITKGQKGT 134
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
L +M D+ F+DDG V+S +V+ AM S + I+AH ED + GG M+E
Sbjct: 135 ALVEMGDLKQAGCVGFSDDGLNVESGDVLRRAMEYASGFDMPIIAHAEDEGIKCGGVMNE 194
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G+ + ELG+ G P + E++ +ARD++LAE HVCHIS + +V +RE K ++VT
Sbjct: 195 GRVATELGLAGNPWVAEASTVARDLMLAELTGARLHVCHISTRRTVELIREAKARGVKVT 254
Query: 249 CEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEE 308
CEVTPHH +E ++ + KM PPLR +D A+ G+ DGTID IATDHAPH +++
Sbjct: 255 CEVTPHHFTLTEEAVRGYDVNAKMGPPLRTADDVKAMKEGLADGTIDAIATDHAPHHVDD 314
Query: 309 KIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENS 368
K ++ G+VG ETA L VK + +L + ++ A + +P G L + +
Sbjct: 315 KNVEFNVAANGLVGLETALP-LALNLVKEGVLTLNQAICCLTTRPASVMRIPRGTLAKGT 373
Query: 369 FADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
ADI +ID + + T++ + +K RNTP+ ++ G ++T+ GKI +
Sbjct: 374 AADITLIDPDYQWTLDATQMKTKARNTPFDGWELTGAAMMTMCAGKITF 422
>gi|154148442|ref|YP_001406526.1| dihydroorotase (DHOase) [Campylobacter hominis ATCC BAA-381]
gi|153804451|gb|ABS51458.1| dihydroorotase (DHOase) [Campylobacter hominis ATCC BAA-381]
Length = 426
Score = 280 bits (717), Expect = 9e-74, Method: Composition-based stats.
Identities = 165/421 (39%), Positives = 250/421 (59%), Gaps = 8/421 (1%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN ++ +K+++LI++DKI K++ N D + ID K++ V G ID HVH+R
Sbjct: 3 ILIKNGTVINATGRQKINVLIENDKILKLT-NSDEKADKIIDAKEKLVMPGLIDMHVHFR 61
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
+PGF K+ + T S A GG TT M M N NPV D+ ++ K +I +P G
Sbjct: 62 DPGFEYKDDINTGSECAVAGGVTTCMCMANTNPVNDNRTITEAMIKKAKAKGLIDLLPIG 121
Query: 121 AITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
AITK+ G+++ +M D I AF+DDG V ++VM +A+ + ++ HCED S
Sbjct: 122 AITKDFEGKKIVEMGDMIEGGCVAFSDDGLPVTDSSVMRQALEYSAYFGTFVINHCEDCS 181
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
L GG M+EGK SA LG+KG+ S E +ARD+LLA+ H H+ H+S+ S++ + +
Sbjct: 182 LCHGGVMNEGKVSAILGLKGMASEKEEIMVARDLLLAKKTGGHIHIAHVSSLWSLKLIEQ 241
Query: 240 GKKNNIRVTCEVTPHHLLSCDED--IKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
KK+ I VTCEVTPHH S DE+ I D +KM+PPLR +D A+ + +G ID+I
Sbjct: 242 AKKDGINVTCEVTPHH-FSFDENRLITYDTN-YKMSPPLRTNKDLAAIRTALKNGMIDVI 299
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH+ ++K +K+ FGI+G +T L VK I SLE +V L S A+I
Sbjct: 300 ATDHAPHSWDDKFVEFDKAPFGILGLQT-LVPLTLNLVKEGIISLEKMVSLCSARPAEIL 358
Query: 358 NLP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
N+ G+++ + ADI +ID + + + SK N+P N+++ G + TI NG++
Sbjct: 359 NIKNKGEIKAGNIADIAIIDPDLKYIYDKNLNKSKSINSPLFNKELTGAAICTIKNGRVV 418
Query: 417 Y 417
+
Sbjct: 419 F 419
>gi|15606174|ref|NP_213551.1| dihydroorotase [Aquifex aeolicus VF5]
gi|3914514|sp|O66990|PYRC_AQUAE Dihydroorotase (DHOase)
gi|2983361|gb|AAC06948.1| dihydroorotase [Aquifex aeolicus VF5]
Length = 422
Score = 280 bits (716), Expect = 1e-73, Method: Composition-based stats.
Identities = 166/406 (40%), Positives = 238/406 (58%), Gaps = 10/406 (2%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
DIL+++ KI+KI +NI V + ID K V GFID HVH R+PG + KE + + SR A
Sbjct: 23 DILVENGKIKKIDKNILVPEAEIIDAKGLIVCPGFIDIHVHLRDPGQTYKEDIESGSRCA 82
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI 137
GGFTT++ MPN NP D+ +N L+ K+ + R +P G ITK G+E++D +
Sbjct: 83 VAGGFTTIVCMPNTNPPIDNTTVVNYILQKSKSVGLCRVLPTGTITKGRKGKEIADFYSL 142
Query: 138 ADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELG 196
+ AFTDDG V ++VM +A+ + S+L I+ HCED+ L G ++EG+ SA LG
Sbjct: 143 KEAGCVAFTDDGSPVMDSSVMRKALELASQLGVPIMDHCEDDKLAYG-VINEGEVSALLG 201
Query: 197 IKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHL 256
+ E QIARD +LA+ H H+ H+S K S+ + K+ +++TCEV P+HL
Sbjct: 202 LSSRAPEAEEIQIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHL 261
Query: 257 LSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKS 316
L + ++ ++NPPLR +EDR ALI GV G ID ATDHAPH EK +E +
Sbjct: 262 LFTEREVLNSGANARVNPPLRKKEDRLALIEGVKRGIIDCFATDHAPHQTFEK-ELVEFA 320
Query: 317 SFGIVGSETAFT---QLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
GI+G +TA +LY K I SL+ L+++ + N A+I + G L+ S ADI
Sbjct: 321 MPGIIGLQTALPSALELYRK----GIISLKKLIEMFTINPARIIGVDLGTLKLGSPADIT 376
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
+ D KE +N E LSK RNTP + + G + TI +GK+ Y D
Sbjct: 377 IFDPNKEWILNEETNLSKSRNTPLWGKVLKGKVIYTIKDGKMVYKD 422
>gi|147669650|ref|YP_001214468.1| dihydroorotase, multifunctional complex type [Dehalococcoides sp.
BAV1]
gi|146270598|gb|ABQ17590.1| dihydroorotase, multifunctional complex type [Dehalococcoides sp.
BAV1]
Length = 428
Score = 279 bits (714), Expect = 2e-73, Method: Composition-based stats.
Identities = 170/424 (40%), Positives = 244/424 (57%), Gaps = 8/424 (1%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHV 57
+L+KN +I+ +G D+LI++ + I+++I E ID + V GFID HV
Sbjct: 3 ILIKNGRIIDPASGTDNVADLLIENGLVTGINKDISREKTEKVIDATGKVVCPGFIDLHV 62
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H REPGF KET+ + +AAA GGFT++ MPN NP D + ++ S+IR +
Sbjct: 63 HLREPGFEAKETIESGCKAAAAGGFTSICPMPNTNPAADCLPVIDFIKNTATKVSLIRVL 122
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P AITK G+ELS M ++A+ V F+DDG V S++++ A+L + I+ HCE
Sbjct: 123 PIAAITKGRKGQELSPMGELAEAGVVGFSDDGDYVSSSSLLLNALLYSRTFDLPIMEHCE 182
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D L GG M+EG + LG+KGI + E + RDI LA+ + H+CHIS SV
Sbjct: 183 DACLAEGGLMNEGLLACRLGLKGITNATEEIAVNRDIALAKESGGRLHLCHISTAGSVEL 242
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
VR+ K IRV+ EVTPHHL + ++ N K+NPPLR + D ALIAG+ DGTID
Sbjct: 243 VRQAKAAGIRVSAEVTPHHLTLTEAEVNGYNTSAKVNPPLRTQTDIEALIAGLKDGTIDA 302
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPHT +K+ ++ GI G ETA V + SL +L++ ++ ++
Sbjct: 303 IATDHAPHTRNDKLCEFGLAANGISGLETALASP-MGLVHSGKLSLSLLIEKLTLGPQQV 361
Query: 357 FNLPY---GKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
Y G L+ S AD+V+ D ++E TI+ +F SKG+NTP K+ G TI+ G
Sbjct: 362 LGEKYQNIGNLKAGSCADVVIFDPDEEWTIDTAKFFSKGKNTPLEGRKLKGRVKTTIACG 421
Query: 414 KIAY 417
+I Y
Sbjct: 422 QIVY 425
>gi|153853806|ref|ZP_01995162.1| hypothetical protein DORLON_01153 [Dorea longicatena DSM 13814]
gi|149753556|gb|EDM63487.1| hypothetical protein DORLON_01153 [Dorea longicatena DSM 13814]
Length = 421
Score = 279 bits (713), Expect = 3e-73, Method: Composition-based stats.
Identities = 159/406 (39%), Positives = 235/406 (57%), Gaps = 4/406 (0%)
Query: 15 KKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTAS 74
+ +DIL+K+ KI +I+ I E ++ V G ID HVH+R+PGF+ KE ++T +
Sbjct: 17 EHMDILVKNGKIARIAPEISEDSEEILEAGGLVVGPGLIDTHVHFRDPGFTYKEDIHTGA 76
Query: 75 RAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDM 134
+A+A+GGFTTV+ M N +P D+ +TL L + IR AI++ G++ DM
Sbjct: 77 KASAKGGFTTVICMANTSPTVDNTDTLKDNLARASKED-IRIFQAAAISRSLKGQDEVDM 135
Query: 135 EDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSA 193
+ + FTDDG + +A Y+AM +KLN I H ED + IR ++ GK S
Sbjct: 136 LALKEAGACGFTDDGIPLLNAEFCYQAMKNAAKLNVPISLHEEDPAFIRNNGINHGKVSD 195
Query: 194 ELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTP 253
LGI G PSI E +ARD LLA + + HIS+ S+ +R KK ++ E TP
Sbjct: 196 ALGIYGSPSIAEEALVARDCLLALRSGADVVIQHISSGVSIDLIRTYKKLGAKLHAEATP 255
Query: 254 HHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGI 313
HH ++ + E + KMNPPLR DR +IAG+ DGTID+IATDHAPH+ EEK + I
Sbjct: 256 HHFSLTEDAVLEHGTLAKMNPPLRTENDRQQIIAGLADGTIDLIATDHAPHSTEEKSKPI 315
Query: 314 EKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
++ GI+G ET+ T VK ++ L++ M+ N AK+++LPYG ++E + AD V
Sbjct: 316 TEAPSGIIGLETSLALGITNLVKPGYLTMIQLLEKMTVNPAKLYHLPYGTIQEGADADFV 375
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
+ D ++ T P+E+ SK N+P+ E++ G TI G I Y D
Sbjct: 376 IFDPDE--TWIPKEYASKSSNSPFTGEELTGKVKYTICGGNIVYSD 419
>gi|77919213|ref|YP_357028.1| dihydrooratase [Pelobacter carbinolicus DSM 2380]
gi|77545296|gb|ABA88858.1| dihydrooratase [Pelobacter carbinolicus DSM 2380]
Length = 425
Score = 279 bits (713), Expect = 3e-73, Method: Composition-based stats.
Identities = 156/420 (37%), Positives = 232/420 (55%), Gaps = 4/420 (0%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+ N ++L +G +K D+LI+D++I ++ +I D ID V G ID HVH
Sbjct: 3 ILITNGRVLDPAHGIDEKFDVLIEDNRIAQVGTDIQTADAEKIDAAGCLVVPGLIDIHVH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
R+PGF KE + + +RAAA GGFT V MPN +PV D+ T L + P
Sbjct: 63 LRDPGFEYKEDIESGTRAAAAGGFTAVACMPNTSPVNDNKATTQYILHKAAQAGHAKVYP 122
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
GAITK G L+++ D+ A TDDG V +M A+ + IV+H ED
Sbjct: 123 VGAITKGLKGESLAELGDMKQAGCVAVTDDGHPVSHGEIMRRALEYARSFDLPIVSHSED 182
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
SL+ G M++G + ELG++GIP + E + +ARD++LAE N HV H+S + +V +
Sbjct: 183 LSLVGDGVMNDGFVATELGLRGIPWVAEVSAVARDVMLAEYTNARLHVAHVSTRGAVEII 242
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K RVT E PH+ ++ ++ + KMNPPLR +D A+ G+ DGT+ +I
Sbjct: 243 RAAKARGARVTAETAPHYFTLTEDAVRGYDTHAKMNPPLRTSDDLEAIREGLADGTLSVI 302
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH +EK + GI+G ETA L + V+ SL + ++ A
Sbjct: 303 ATDHAPHHPDEKNVEFNLALNGIIGLETALP-LTLRLVEEGALSLSDAIACLTSGPAAAL 361
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+LP G LE AD+ +ID E + T++P+ S+ RNTP+ + K+ G + TI +G+I Y
Sbjct: 362 SLPGGTLEVGRPADVTIIDPEIKWTLDPQAGQSRSRNTPFGDWKLKGRAICTIVDGRITY 421
>gi|42520125|ref|NP_966040.1| dihydroorotase [Wolbachia endosymbiont of Drosophila melanogaster]
gi|42409862|gb|AAS13974.1| dihydroorotase [Wolbachia endosymbiont of Drosophila melanogaster]
Length = 459
Score = 278 bits (712), Expect = 3e-73, Method: Composition-based stats.
Identities = 167/410 (40%), Positives = 239/410 (58%), Gaps = 9/410 (2%)
Query: 16 KVDILIKDDKIEKISENIDVTD--ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
K +L + DKI E++ T + TID K + G ID HVH+REPG KET+YT
Sbjct: 53 KGSLLTEGDKIVDFGESLFSTSGVDETIDCKGLVLMPGLIDIHVHFREPGQEHKETIYTG 112
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA--ITKEEYGREL 131
S++AA GG TTV+ PN P DSV L K L+ ++ + + A T EE+ E+
Sbjct: 113 SKSAAAGGVTTVVCQPNTVPAIDSV-ILAKYLKYRALETSHVNVEFYAKITTSEEHLTEM 171
Query: 132 SDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
+ +++ FTDDG V + +M +A+L S LN I H ED +L GGA++EGK
Sbjct: 172 ALLKEAG--AVGFTDDGMPVMNPMIMRQALLYSSMLNVPIAQHAEDLNLSAGGAINEGKI 229
Query: 192 SAELGIKGIPSICESTQIARDILL-AEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
S ELG+KGI S ES + RDILL + N HYH+ H+S+K+S+ A++ K + VTCE
Sbjct: 230 SEELGVKGILSASESVMVNRDILLMKDMENVHYHILHVSSKDSLDAIKRAKDLGLNVTCE 289
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
VTPHH ++ +K+ + KMNPPLR EDR A++ G+ G ID IATDHAPH K
Sbjct: 290 VTPHHFTLTEDIVKQHGAIAKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKD 349
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
+E ++FGIVG ET + + L++L KL + A I ++P G++++N A
Sbjct: 350 LPLENAAFGIVGLETMLPLSLELYHSGQMGLLDVLAKL-TYKPADIIHIPRGRIQKNLAA 408
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
D++++DL E I + F SK +N+P+ KV G V T+ +GK Y K
Sbjct: 409 DLILVDLNHEWEIKTDNFASKSKNSPFDGRKVKGHVVRTVVSGKTIYSQK 458
>gi|99034628|ref|ZP_01314581.1| hypothetical protein Wendoof_01000603 [Wolbachia endosymbiont of
Drosophila willistoni TSC#14030-0811.24]
Length = 458
Score = 278 bits (712), Expect = 3e-73, Method: Composition-based stats.
Identities = 167/410 (40%), Positives = 239/410 (58%), Gaps = 9/410 (2%)
Query: 16 KVDILIKDDKIEKISENIDVTD--ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
K +L + DKI E++ T + TID K + G ID HVH+REPG KET+YT
Sbjct: 52 KGSLLTEGDKIVDFGESLFSTSGVDETIDCKGLVLMPGLIDIHVHFREPGQEHKETIYTG 111
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA--ITKEEYGREL 131
S++AA GG TTV+ PN P DSV L K L+ ++ + + A T EE+ E+
Sbjct: 112 SKSAAAGGVTTVVCQPNTVPAIDSV-ILAKYLKYRALETSHVNVEFYAKITTSEEHLTEM 170
Query: 132 SDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
+ +++ FTDDG V + +M +A+L S LN I H ED +L GGA++EGK
Sbjct: 171 ALLKEAG--AVGFTDDGMPVMNPMIMRQALLYSSMLNVPIAQHAEDLNLSAGGAINEGKI 228
Query: 192 SAELGIKGIPSICESTQIARDILL-AEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
S ELG+KGI S ES + RDILL + N HYH+ H+S+K+S+ A++ K + VTCE
Sbjct: 229 SEELGVKGILSASESVMVNRDILLMKDMENVHYHILHVSSKDSLDAIKRAKDLGLNVTCE 288
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
VTPHH ++ +K+ + KMNPPLR EDR A++ G+ G ID IATDHAPH K
Sbjct: 289 VTPHHFTLTEDIVKQHGAIAKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKD 348
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
+E ++FGIVG ET + + L++L KL + A I ++P G++++N A
Sbjct: 349 LPLENAAFGIVGLETMLPLSLELYHSGQMGLLDVLAKL-TYKPADIIHIPRGRIQKNLAA 407
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
D++++DL E I + F SK +N+P+ KV G V T+ +GK Y K
Sbjct: 408 DLILVDLNHEWEIKTDNFASKSKNSPFDGRKVKGHVVRTVVSGKTIYSQK 457
>gi|124515272|gb|EAY56782.1| Dihydroorotase [Leptospirillum sp. Group II UBA]
Length = 438
Score = 278 bits (712), Expect = 4e-73, Method: Composition-based stats.
Identities = 149/380 (39%), Positives = 219/380 (57%), Gaps = 10/380 (2%)
Query: 48 VTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVET----LNK 103
VT G +D H H+REPGF KET+ + SRAA GGFT V M N +PV D E +NK
Sbjct: 60 VTPGLVDVHAHFREPGFEYKETIESGSRAAVSGGFTAVCVMANTDPVNDHPEVTLGMINK 119
Query: 104 QLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAML 162
EI + R P GA++ G L++M + F+DDG V+++ ++ A+
Sbjct: 120 AREI----GLCRVFPIGAVSLGLKGETLTEMGALVRAGCVGFSDDGLPVKTSRLLRRALE 175
Query: 163 MGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCH 222
+ ++ ++ HCED L GG M+EG S +LG++GIP+ E +ARD+ + +
Sbjct: 176 YAALFHRPVIDHCEDRDLSDGGVMNEGWVSTDLGLRGIPAASEEVVVARDLEILKTTRGR 235
Query: 223 YHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDR 282
HV H+S VR VRE KK ++ VT E PH+ DE ++ + KMNPPLR EDR
Sbjct: 236 LHVAHLSTAGGVRLVREAKKRHLHVTAETCPHYFSLTDEAVRCHHADAKMNPPLRTEEDR 295
Query: 283 NALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSL 342
A+I G+ DGTID+IATDHAPH EK R +++ FGI+G ETAF+ L + V + + L
Sbjct: 296 LAIIEGLRDGTIDMIATDHAPHAPFEKEREFDQAPFGIIGLETAFS-LGLQLVNSGVLDL 354
Query: 343 EMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKV 402
ML+ LMS +++F LP G++ AD++V D ++ F S+ RN+P++ +K+
Sbjct: 355 SMLLYLMSVRPSRVFGLPRGEIRVGGMADLMVFDPKQSTVAGVPRFHSRSRNSPFSGQKL 414
Query: 403 NGIPVLTISNGKIAYIDKEE 422
G +T GK + +EE
Sbjct: 415 PGRVRMTFVGGKKVFDVREE 434
>gi|146296937|ref|YP_001180708.1| dihydroorotase, multifunctional complex type [Caldicellulosiruptor
saccharolyticus DSM 8903]
gi|145410513|gb|ABP67517.1| dihydroorotase, multifunctional complex type [Caldicellulosiruptor
saccharolyticus DSM 8903]
Length = 430
Score = 278 bits (711), Expect = 4e-73, Method: Composition-based stats.
Identities = 163/420 (38%), Positives = 247/420 (58%), Gaps = 5/420 (1%)
Query: 1 MLLKNCKILKN--GKFKKVDILIKDDKIEKISENIDVTDE--NTIDVKDRFVTAGFIDAH 56
+L+KN +I+ + K +K DILI DDKI+KI ++I+ E ID + V F D H
Sbjct: 2 ILIKNAQIINSLHDKVEKADILIVDDKIKKIGKDIEENPEKMTIIDASGKVVMPSFTDIH 61
Query: 57 VHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRA 116
H REPGF KE + + SR+AA GGFTT+ MPN NP D+ + + S I
Sbjct: 62 CHLREPGFEYKEDIKSGSRSAAAGGFTTICCMPNTNPPVDNRAMVAYIKYRAREVSPIEV 121
Query: 117 IPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHC 175
+P GAITK G EL+++ + ++ A +DDG+ V +AN+M A+L + +++HC
Sbjct: 122 LPVGAITKGLLGEELAEIGFMKEEGAIAISDDGKCVMNANLMKNALLYSRDFSIPVISHC 181
Query: 176 EDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVR 235
ED +L GG ++ G S G++GIP ES IARDILLA+ H H+ H+S KESVR
Sbjct: 182 EDTNLSEGGQINLGYVSTITGLRGIPREAESVIIARDILLAKETKSHLHITHVSTKESVR 241
Query: 236 AVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTID 295
++ K+ + VT + PH++ +E++ N K+NPPLR +ED ALI G+ +G ID
Sbjct: 242 LIKMAKEWGVNVTADTCPHYISLTEEEVLGFNTNAKVNPPLRTQEDVEALIEGLKEGVID 301
Query: 296 IIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
I+TDHAPH +EK ++ G +G ETAF+ L+T V+ + F + +V+L++ N K
Sbjct: 302 CISTDHAPHHKDEKNVEFNLAASGTIGFETAFSVLFTYLVEKNGFDIGKIVELLNHNPRK 361
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
I L L+E A++V++DL+K+ + E +SK +N+ + + + I NGKI
Sbjct: 362 IIGLSPNVLKEGEKANLVIVDLKKKWEVKEENIVSKSKNSVFLGKLLTSYVETVIYNGKI 421
>gi|153005053|ref|YP_001379378.1| dihydroorotase, multifunctional complex type [Anaeromyxobacter sp.
Fw109-5]
gi|152028626|gb|ABS26394.1| dihydroorotase, multifunctional complex type [Anaeromyxobacter sp.
Fw109-5]
Length = 433
Score = 278 bits (710), Expect = 7e-73, Method: Composition-based stats.
Identities = 160/403 (39%), Positives = 220/403 (54%), Gaps = 5/403 (1%)
Query: 19 ILIKDDKIEKISENID-VTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
++++D K+ +++ ++ D ID + ++VT GFID HVH REPG KET+ T +RAA
Sbjct: 25 VVVRDGKVAEVAARLERPRDARAIDARGKWVTPGFIDLHVHLREPGQEYKETIATGARAA 84
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDM-ED 136
GGFT V MPN PV D+ L + R P GAI+K G EL++ E
Sbjct: 85 VAGGFTAVCAMPNTKPVNDNASVTELVLARAAAAGLARVYPVGAISKGSNGEELAEYGEL 144
Query: 137 IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELG 196
+A A +DDGR V SA +M A+ + H E+ L+ G MHEG S LG
Sbjct: 145 LASGCVALSDDGRPVLSAALMRRALEYARAFGLPLTVHEEELQLVGKGVMHEGAASTRLG 204
Query: 197 IKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHL 256
+KGIP E + RDI L E HV H+S K +VRA+R+ K + VT EVTPHHL
Sbjct: 205 LKGIPGAAEDVMVLRDIALVELTGGRLHVAHVSTKGAVRAIRDAKARGLPVTGEVTPHHL 264
Query: 257 LSCDEDIKED--NGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIE 314
DED+ + +KMNPPLR ED A G+ DGT+D IATDHAPH+ EK +
Sbjct: 265 ALTDEDVAASGYSTDYKMNPPLRSAEDVRACREGLADGTLDAIATDHAPHSAVEKDVEFD 324
Query: 315 KSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVV 374
++ GI G ETAF + V+ S LV+ ++ A+ F L G L AD+ V
Sbjct: 325 AAANGITGLETAFP-VCLDLVRAGALSERRLVEALTSGPARAFGLAGGTLAAGVPADVAV 383
Query: 375 IDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+D E T++P SK RNTP+ ++ G ++TI G+I +
Sbjct: 384 LDPVAEWTVDPARMYSKSRNTPWKGRRLTGRCLITIVGGRIVH 426
>gi|86158044|ref|YP_464829.1| dihydroorotase, multifunctional complex type [Anaeromyxobacter
dehalogenans 2CP-C]
gi|85774555|gb|ABC81392.1| dihydroorotase, multifunctional complex type [Anaeromyxobacter
dehalogenans 2CP-C]
Length = 433
Score = 275 bits (704), Expect = 3e-72, Method: Composition-based stats.
Identities = 161/403 (39%), Positives = 226/403 (56%), Gaps = 5/403 (1%)
Query: 19 ILIKDDKIEKISENID-VTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
++I+D K+ +++E ++ D +D ++R+VT GF+D HVH REPG KETV T +RAA
Sbjct: 25 VVIRDGKVAEVAERVERPRDARVLDARNRWVTPGFVDLHVHLREPGQEYKETVATGARAA 84
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI 137
GGFT V MPN PV D L + R P GAI+K G EL++ ++
Sbjct: 85 VAGGFTAVCAMPNTKPVNDCAAVTELVLARAAAAGLARVYPVGAISKGSGGEELAEYGEL 144
Query: 138 -ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELG 196
A A +DDGR V S+ +M A+ + H ED L+ G MHEG + LG
Sbjct: 145 KASGCVALSDDGRPVMSSALMRRALEYARAFGLPLTVHEEDLHLVGKGVMHEGAAATRLG 204
Query: 197 IKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHL 256
+KGIPS E + RDI L E HV H+S +VRA+RE K+ + VT EVTPHHL
Sbjct: 205 LKGIPSQAEDVMVLRDIALVELTGGRLHVAHVSTAGAVRAIREAKRRGLPVTGEVTPHHL 264
Query: 257 LSCDEDIKED--NGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIE 314
D+D+ + +KMNPPLR +D A G+ DGT+D IATDHAPH+ EK +
Sbjct: 265 ALTDDDVAASGYSTDFKMNPPLRSADDVRACREGLADGTLDAIATDHAPHSAVEKDVEFD 324
Query: 315 KSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVV 374
++ GIVG ETAF+ + V+ + LV+ ++ A++F LP G L + AD+ V
Sbjct: 325 AAANGIVGLETAFS-VCLGLVREGALTERRLVEALTAGPARVFGLPAGTLARGAAADVAV 383
Query: 375 IDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+D E T++P SKGRNTP+ ++ G TI G+I +
Sbjct: 384 LDAAAEWTLDPARLQSKGRNTPWKGRRLAGRCTHTIVGGRIVH 426
>gi|58696674|ref|ZP_00372226.1| dihydroorotase [Wolbachia endosymbiont of Drosophila simulans]
gi|58698216|ref|ZP_00373136.1| dihydroorotase [Wolbachia endosymbiont of Drosophila ananassae]
gi|58535243|gb|EAL59322.1| dihydroorotase [Wolbachia endosymbiont of Drosophila ananassae]
gi|58537156|gb|EAL60262.1| dihydroorotase [Wolbachia endosymbiont of Drosophila simulans]
Length = 459
Score = 275 bits (703), Expect = 4e-72, Method: Composition-based stats.
Identities = 167/415 (40%), Positives = 237/415 (57%), Gaps = 19/415 (4%)
Query: 16 KVDILIKDDKIEKISENIDVTD--ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
K +L + DKI E++ T + TID K + G ID HVH+REPG KET+YT
Sbjct: 53 KGSLLTEGDKIVDFGESLFSTSGVDETIDCKGLVLMPGLIDIHVHFREPGQEHKETIYTG 112
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR---- 129
S++AA GG TTV+ PN P DSV L K L+ RA+ + E Y +
Sbjct: 113 SKSAAAGGVTTVVCQPNTIPAIDSV-VLAKYLKY-------RALETSHVNVEFYAKITTL 164
Query: 130 --ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAM 186
+L++M + + FTDDG V + +M +A+L S L I H ED +L GGA+
Sbjct: 165 EEKLTEMALLKEAGAVGFTDDGMPVMNPMIMRQALLYSSMLGVPIAQHAEDLNLSAGGAI 224
Query: 187 HEGKRSAELGIKGIPSICESTQIARDILL-AEAANCHYHVCHISAKESVRAVREGKKNNI 245
+EGK S ELG+KGI S ES + RDILL + N HYH+ H+S+K+S+ A++ K +
Sbjct: 225 NEGKISEELGVKGILSASESVMVNRDILLMKDMENVHYHILHVSSKDSLDAIKRAKDLGL 284
Query: 246 RVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHT 305
VTCEVTPHH ++ +K+ + KMNPPLR EDR A++ G+ G ID IATDHAPH
Sbjct: 285 NVTCEVTPHHFTLTEDIVKQHGAIAKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHD 344
Query: 306 MEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLE 365
K +E ++FGIVG ET + + L++L KL + A I ++P G+++
Sbjct: 345 RSSKDLPLENAAFGIVGLETMLPLSLELYHSGQMGLLDVLAKL-TYKPADIIHIPRGRIQ 403
Query: 366 ENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
+N AD++++DL E I + F SK +N+P+ KV G V T+ +GK Y K
Sbjct: 404 KNLAADLILVDLNHEWEIKTDNFASKSKNSPFDGRKVKGHVVRTVVSGKTIYSQK 458
>gi|109672522|ref|ZP_01374759.1| dihydroorotase [Campylobacter concisus 13826]
gi|112801389|gb|EAT98733.1| chaperone protein HtpG (Heat shock protein htpG; High
temperatureprotein G) [Campylobacter concisus 13826]
Length = 425
Score = 275 bits (703), Expect = 4e-72, Method: Composition-based stats.
Identities = 168/418 (40%), Positives = 241/418 (57%), Gaps = 8/418 (1%)
Query: 5 NCKILKNGKFKKVDILIKDDKIEKI-SENIDVTDENTIDVKDRFVTAGFIDAHVHWREPG 63
N I+ + + K +ILI++ KI KI SE + + ID ++ V G ID HVH+R+PG
Sbjct: 7 NGTIVNSDEKFKANILIENGKIAKIGSEKFEA--DKVIDATNKLVMPGLIDMHVHFRDPG 64
Query: 64 FSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAIT 123
K+ + + S+AA GG TT + M N NPV D+ +E KN +I +P AI+
Sbjct: 65 QEYKDDIISGSQAAVAGGVTTCLCMANTNPVNDNASITRAMIEKAKNCGLIDLLPIAAIS 124
Query: 124 KEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIR 182
K G E+ +M D+ + AF+DDG V S++VM A+ S N ++H ED SL R
Sbjct: 125 KGLGGNEIVEMGDLIEAGAVAFSDDGLPVTSSSVMRAALEYSSMFNSFCISHSEDCSLCR 184
Query: 183 GGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKK 242
G MHEGK SA LG++G+ E ++RD+LLA+ H H+ H+S++ S++ + GKK
Sbjct: 185 QGVMHEGKVSAILGLRGMAREKEEIAVSRDMLLAKLTKAHIHIAHVSSEYSLKIIEMGKK 244
Query: 243 NNIRVTCEVTPHHLLSCDEDIKED--NGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
I +TCE TPHH D++I ++ + +KM+PPLR D A+ + G ID+IATD
Sbjct: 245 EGINITCEATPHHFSFSDDEILKNAYDTNFKMSPPLREISDVKAVREALKSGLIDVIATD 304
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPH +EKI +K+ FGI+G +T L K V + SLE +V+L S N AK+ NL
Sbjct: 305 HAPHHTDEKIVEFDKAPFGIIGLQT-LVPLTLKLVDEGVISLERMVELTSTNAAKMLNLK 363
Query: 361 -YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+L E ADI VID E E + + SK N+P +K+ G TI +GKI Y
Sbjct: 364 DKGRLAEGMLADITVIDPEIEYIYDEKINRSKSVNSPLFGKKLKGAATTTIKSGKIVY 421
>gi|148263914|ref|YP_001230620.1| dihydroorotase, multifunctional complex type [Geobacter
uraniumreducens Rf4]
gi|146397414|gb|ABQ26047.1| dihydroorotase, multifunctional complex type [Geobacter
uraniumreducens Rf4]
Length = 425
Score = 272 bits (696), Expect = 3e-71, Method: Composition-based stats.
Identities = 151/403 (37%), Positives = 230/403 (57%), Gaps = 3/403 (0%)
Query: 17 VDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASR 75
+D+L++D +I++I + + ID VT G ID HVH R+PG KE + T +R
Sbjct: 21 MDLLVEDGRIKEIGKGLKAPAGAEIIDAAGLLVTPGLIDMHVHLRDPGLEYKEDIVTGTR 80
Query: 76 AAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDME 135
AAA GGFT+V MPN PV D+ + + ++++ P G+IT+ G L++M
Sbjct: 81 AAAAGGFTSVACMPNTKPVNDNKAITSYIVNKAAKEALVNVFPVGSITQGSKGESLAEMG 140
Query: 136 DIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAE 194
++ + A +DDGR V + +M A+ + +++H E+ +L+ G M+EG + E
Sbjct: 141 ELKESGCVAVSDDGRPVVNGELMRRALEYAKGMGIMVISHSEELALVGEGVMNEGFTATE 200
Query: 195 LGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPH 254
LG+KGIP E +ARD+ LAE + H+ HIS SVR +R K ++VTCE PH
Sbjct: 201 LGLKGIPWAAEDVAVARDVYLAEFTDSPLHIAHISTSGSVRIIRNAKARGVKVTCETAPH 260
Query: 255 HLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIE 314
+ D+ ++ N KMNPPLR D A+ AG+ DGTID IATDHAPH ++EK
Sbjct: 261 YFSLTDDAVRGYNTNAKMNPPLREAADVAAIKAGLADGTIDAIATDHAPHHLDEKDLEFN 320
Query: 315 KSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVV 374
+ GIVG ET+ L + V+ + L++L++ M+ N AKI + G L+ + ADI V
Sbjct: 321 LALNGIVGLETSLP-LSLQLVEEGVVDLKVLLEKMTCNPAKILGIDRGTLKVGAAADITV 379
Query: 375 IDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
ID ++E + E+ SK +N+P+ K+ G V T+ GK+ Y
Sbjct: 380 IDPDREWLVAAEKLASKSKNSPFIGRKMKGAAVYTVVGGKVVY 422
>gi|154174272|ref|YP_001408031.1| dihydroorotase (DHOase) [Campylobacter curvus 525.92]
gi|112802885|gb|EAU00229.1| dihydroorotase (DHOase) [Campylobacter curvus 525.92]
Length = 425
Score = 272 bits (696), Expect = 3e-71, Method: Composition-based stats.
Identities = 162/420 (38%), Positives = 241/420 (57%), Gaps = 8/420 (1%)
Query: 3 LKNCKILKNGKFKKVDILIKDDKIEKI-SENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
+KN ++ + K K ++LI +KI ++ SE+ID + ID + V G ID HVH+R+
Sbjct: 5 IKNATVVNHDKKFKANVLIDGEKIARVTSEDIDA--DTVIDATGKLVMPGLIDMHVHFRD 62
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG+ K+ + + S AA GG TT + M N NPV D+ + K +I +P A
Sbjct: 63 PGYEYKDDIISGSEAAVAGGVTTCLCMANTNPVNDNASITRAMIAKAKACGLIDLLPIAA 122
Query: 122 ITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
I+K G E+ +M D+ + AF+DDG V +++VM A+ S ++H ED SL
Sbjct: 123 ISKGLGGNEIVEMGDLIEAGAVAFSDDGLPVTNSSVMRAALEYSSMFGSFCISHSEDCSL 182
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
R G MHEGK SA LG+KG+ E ++RD+LLA+ H H+ H+S++ S++ + G
Sbjct: 183 CRQGVMHEGKVSAILGLKGMAREKEEIAVSRDMLLAKLTKAHIHIAHVSSQYSLKIIEMG 242
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDN--GMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+K I +TCE TPHH D++I ++N +KM+PPLR D A+ + G ID+IA
Sbjct: 243 RKEGIHITCEATPHHFSFSDDEILKNNYDANFKMSPPLREISDVMAVREALKSGLIDVIA 302
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH +EK +K+ FGI+G +T L K V + SLE +V+L S N AK+ N
Sbjct: 303 TDHAPHHSDEKEVEFDKAPFGIIGLQT-LVPLTLKLVNEGVISLERMVELTSTNAAKMLN 361
Query: 359 LP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L G++ E ADI +ID E E + + SK N+P +K+ G V+TI +G+I Y
Sbjct: 362 LKDKGEVAEGMLADIAIIDPEIEYIYDEKINRSKSTNSPLFGKKLKGAAVVTIKSGRIVY 421
>gi|153815090|ref|ZP_01967758.1| hypothetical protein RUMTOR_01314 [Ruminococcus torques ATCC 27756]
gi|145847658|gb|EDK24576.1| hypothetical protein RUMTOR_01314 [Ruminococcus torques ATCC 27756]
Length = 421
Score = 270 bits (691), Expect = 1e-70, Method: Composition-based stats.
Identities = 165/424 (38%), Positives = 239/424 (56%), Gaps = 13/424 (3%)
Query: 1 MLLKNCKIL-----KNGKFKKVDILIKDDKIEKISENID-VTDENTIDVKDRFVTAGFID 54
ML+KN ++ K+G + DI IK+ I +I + +E D V G ID
Sbjct: 1 MLIKNGFLIDPATKKSGNY---DIRIKNGIITEIGNTLSPAPNEQVTDAAGLTVAPGLID 57
Query: 55 AHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVI 114
H+H+R+PGF+ KE ++T S+AAA GGFT+V+ M N +PV D+ ETL LE K D I
Sbjct: 58 THIHFRDPGFTYKENIHTGSQAAAAGGFTSVICMANTSPVVDNTETLTDILERAK-DEKI 116
Query: 115 RAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVA 173
+++ + G E++DME + FTDDG +++A +YEAM +LN I
Sbjct: 117 HVYQAASVSHKLRGEEMTDMEALKTAGACGFTDDGIPLKNAAFLYEAMEKSKQLNVPISL 176
Query: 174 HCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKES 233
H ED S I+ ++ G S +LGI G PSI E + +ARD ++A + + HIS+ S
Sbjct: 177 HEEDPSFIKNNGVNHGAVSEQLGIYGSPSIAEESLVARDCMIALHSGADVVMQHISSGRS 236
Query: 234 VRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGT 293
V +R K + E TPHH DE + + KMNPPLR DR A+IAG+ DGT
Sbjct: 237 VDIIRHFKSLGANIHTEATPHHFTLTDEAVLTYGTLAKMNPPLRSEADRQAIIAGLADGT 296
Query: 294 IDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENV 353
IDIIATDHAPH+ EEK R I + GI+G ET+ T V+ SL L++ M+ N
Sbjct: 297 IDIIATDHAPHSKEEKERSITAAPSGIIGLETSLALGITSLVRKGHLSLMQLLEKMTINP 356
Query: 354 AKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
A++++L GK+E+ + AD+V+ D E + PE F S N+P+ ++ G +T+ G
Sbjct: 357 ARLYHLDGGKIEKGAPADLVIFDPEAKWI--PEFFASMSSNSPFIGWELYGKVKMTVCGG 414
Query: 414 KIAY 417
+I Y
Sbjct: 415 EIVY 418
>gi|78222979|ref|YP_384726.1| Dihydroorotase multifunctional complex type [Geobacter
metallireducens GS-15]
gi|78194234|gb|ABB32001.1| Dihydroorotase multifunctional complex type [Geobacter
metallireducens GS-15]
Length = 422
Score = 270 bits (690), Expect = 1e-70, Method: Composition-based stats.
Identities = 153/421 (36%), Positives = 238/421 (56%), Gaps = 5/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHV 57
ML++ +++ G + +DIL+++ ++++ + + + TID VT G ID HV
Sbjct: 1 MLIQGGRVIDPSQGIDEVLDILVENGAVKELGKGVKAPSGTETIDASGLIVTPGLIDMHV 60
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H R+PG KE + + ++AAA GGFT+V MPN PV D+ + + K + +
Sbjct: 61 HLRDPGHEYKEDIVSGTKAAAAGGFTSVACMPNTKPVNDNKAVTSYIIAKAKAEGSVNVF 120
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P G+IT+ G LS+M ++ + A +DDG V ++ +M A+ + +++H E
Sbjct: 121 PVGSITQGSKGELLSEMGELKESGCVAVSDDGHPVTNSELMRRALEYAKGMGIMVISHAE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D SL+ G M+EG S ELG+KGIP E ARD+ LAE + H+ H+S K S+R
Sbjct: 181 DLSLVGAGVMNEGFVSTELGLKGIPWAAEDAATARDVYLAEFTDSPLHIAHVSTKGSLRI 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
+R K ++VTCE PH+ D+ ++ + KMNPPLR +D A+ + DGTID
Sbjct: 241 IRNAKARGVKVTCETAPHYFSLTDDAVRGYDTNAKMNPPLRTADDVTAVKEALKDGTIDA 300
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPH ++EK ++ GIVG ET+ T L + V+ + +L +LV M+ N AKI
Sbjct: 301 IATDHAPHHIDEKDLEFNEALNGIVGLETSLT-LSLRLVEEGVLTLPVLVDKMACNPAKI 359
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L+ S ADI VID + T++ ++ SK +N+P+ +V G TI GK+
Sbjct: 360 LGIDRGTLKPGSVADITVIDPKATWTVDADKLASKSKNSPFLGWEVKGAAAFTIVGGKVV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|118474957|ref|YP_892610.1| dihydroorotase [Campylobacter fetus subsp. fetus 82-40]
gi|118414183|gb|ABK82603.1| dihydroorotase [Campylobacter fetus subsp. fetus 82-40]
Length = 426
Score = 270 bits (690), Expect = 1e-70, Method: Composition-based stats.
Identities = 158/418 (37%), Positives = 235/418 (56%), Gaps = 4/418 (0%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
L+KN I+ K ++LI + I+ I+ D ID ++ V G ID HVH+R+
Sbjct: 4 LIKNGIIINQNGTLKANVLIDGEMIKSITAEEPKADL-VIDATNKLVMPGLIDMHVHFRD 62
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG K+ + T S +A GG TT M N NPV D+ + K +I +P GA
Sbjct: 63 PGLEYKDDIITGSMSAVAGGVTTACPMANTNPVNDNAVVTRDMIAKAKKRGLIDLLPIGA 122
Query: 122 ITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
ITK G+ +++M D+++ AF+DDG V S++VM A+L + I+ H +D SL
Sbjct: 123 ITKGMEGKGITEMGDMSEAGCVAFSDDGLPVSSSDVMRAALLYSAFHKSFIINHSQDCSL 182
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
RGG M+EGK S LGIKG+P E I+RD+LLA+ H HV H+S+ S++ + +
Sbjct: 183 CRGGHMNEGKMSMLLGIKGMPREQEEIMISRDMLLAKLTGGHIHVAHVSSAYSLKLIEQA 242
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K + +TCEVTPHH ++++ + +KM+PPLR D A+ G+ +G ID+I TD
Sbjct: 243 KNEGVNITCEVTPHHFTFSEDELINYDTNFKMSPPLRTNNDVEAMRNGLKNGLIDVICTD 302
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPH +EK +K+ FGI+G +T L V+ + E +VKL S N AKI NL
Sbjct: 303 HAPHHTDEKFLEFDKAPFGILGLQT-LVPLTLNLVREGVIDYEQMVKLTSFNPAKILNLK 361
Query: 361 -YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G ++E ADI +ID + E + SK +N+P +K+ G V+TI +GK+ +
Sbjct: 362 NKGAIKEGFLADIAIIDPDLEYIYDENLNKSKSKNSPLLGKKLKGASVVTIKSGKVVF 419
>gi|145617877|ref|ZP_01773940.1| dihydroorotase, multifunctional complex type [Geobacter
bemidjiensis Bem]
gi|144945924|gb|EDJ80986.1| dihydroorotase, multifunctional complex type [Geobacter
bemidjiensis Bem]
Length = 424
Score = 270 bits (690), Expect = 1e-70, Method: Composition-based stats.
Identities = 157/421 (37%), Positives = 231/421 (54%), Gaps = 5/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDEN-TIDVKDRFVTAGFIDAHV 57
+L+K +++ G +D+LI D + ++ + + + ID VT G ID HV
Sbjct: 3 LLIKGGRVIDPSQGIDANLDVLIADGVVLELGQGLAAPEGTPAIDASGLIVTPGLIDMHV 62
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H R+PG KE + T SR+AA GGFT+V MPN +PV DS + + K+++++
Sbjct: 63 HLRDPGLEYKEDIATGSRSAAAGGFTSVACMPNTSPVIDSKAIASYIINKAKSEALVNVF 122
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P G ITK G L++M ++ + A +DDG+ V ++ +M A+ + A+++H E
Sbjct: 123 PIGCITKGGKGESLAEMGELKEAGCVAVSDDGKPVCNSELMRRALEYAKGIGIAVISHSE 182
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D +L+ G M+EG S ELG+KGIP E +AR++ LAE A H+ HIS S R
Sbjct: 183 DLALVGEGVMNEGFVSTELGLKGIPWAAEDIAVAREVYLAEFAGAPVHIAHISTVGSARI 242
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
+R K ++VTCE PH+ DE ++ KMNPPLR D A+ AG+ DGTID
Sbjct: 243 IRNAKARGVKVTCETAPHYFTLTDEAVRGYETNAKMNPPLRSAADVEAMKAGLADGTIDA 302
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPH +EK + GIVG ET+ + L K V+ L LV LMS AKI
Sbjct: 303 IATDHAPHHPDEKDVEFNVALNGIVGLETSLS-LSLKLVEEGRLDLNQLVSLMSCTPAKI 361
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
L G L+ + D+ +ID KE + + SK +N+P+ K+ G V T+ G++
Sbjct: 362 LGLDRGTLKVGAVGDVTIIDPAKEWQVEAAKLESKSKNSPFLGWKMKGRAVYTVVKGQVV 421
Query: 417 Y 417
Y
Sbjct: 422 Y 422
>gi|58584703|ref|YP_198276.1| Dihydroorotase, PyrC [Wolbachia endosymbiont strain TRS of Brugia
malayi]
gi|58419019|gb|AAW71034.1| Dihydroorotase, PyrC [Wolbachia endosymbiont strain TRS of Brugia
malayi]
Length = 443
Score = 270 bits (689), Expect = 2e-70, Method: Composition-based stats.
Identities = 159/391 (40%), Positives = 222/391 (56%), Gaps = 17/391 (4%)
Query: 38 ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDS 97
+ TI+ + + G +D HVH+REPG KET+YT S++AA GG TTV+ PN P DS
Sbjct: 62 DETINCEGLVLMPGLVDIHVHFREPGQEHKETIYTGSKSAAAGGVTTVVCQPNTTPAIDS 121
Query: 98 VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADKVF-------AFTDDGRG 150
V L K L+ RA+ + E Y + + E + + FTDDG
Sbjct: 122 V-ILAKYLKY-------RALETSHVNIEFYAKITTSEEKLTEVALLKEAGAVGFTDDGIP 173
Query: 151 VQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIA 210
V + +M +A+L S LN I H ED +L GGA++EGK S LG+KGI S ES ++
Sbjct: 174 VMNPMIMRQALLYSSMLNVPIAQHAEDLNLSAGGAINEGKISEALGVKGILSASESVMVS 233
Query: 211 RDILL-AEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGM 269
RDILL + N HYH+ HIS+K+S+ AV+ K + VTCEVTPHH ++ +K+ +
Sbjct: 234 RDILLMKDIENVHYHILHISSKDSLDAVKRAKDLGLNVTCEVTPHHFTLTEDIVKQHGAI 293
Query: 270 WKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQ 329
KMNPPLR EDR A++ G+ G ID IATDHAPH K +E ++FGIVG ET
Sbjct: 294 AKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKDLPLESAAFGIVGLETMLPL 353
Query: 330 LYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFL 389
+ I ++L KL + A I ++P G++++N AD+ ++DL E I + F
Sbjct: 354 SLELYHSGQIDLFDILAKL-TYKPADIIHVPRGRVQKNFVADLTLVDLNYEWEIKIDSFA 412
Query: 390 SKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
SK +N+P+ KV G V TI +GK Y K
Sbjct: 413 SKSKNSPFGGRKVKGRVVRTIVSGKTVYSQK 443
>gi|118444937|ref|YP_878886.1| dihydroorotase [Clostridium novyi NT]
gi|118135393|gb|ABK62437.1| dihydroorotase [Clostridium novyi NT]
Length = 397
Score = 270 bits (689), Expect = 2e-70, Method: Composition-based stats.
Identities = 159/417 (38%), Positives = 243/417 (58%), Gaps = 27/417 (6%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN +I+ + D+ I +KI I +N+ D I+ K + + FID H H+R
Sbjct: 3 LLIKNVRIVDWAQDFYGDVYIYKNKIYDIGKNLS-KDCEIINGKGKVLMPAFIDLHAHFR 61
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
+PGF+ KE + T SRAA RGG+TTV M N NPV +E +N E ++ +I
Sbjct: 62 DPGFTNKEDIITGSRAAVRGGYTTVNLMANTNPVCSDMEVVNYVKEKAQSVGLIEVNQIV 121
Query: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
+ITK+ G ++S ++ + +DDG+GV+ +M EAM+ +++H E
Sbjct: 122 SITKDLKGEDISHLDKLPCSTKFISDDGKGVKDNKIMMEAMIKAKSKGITVISHAE---- 177
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
S E+ + + E+ RDI L + C+ H+ HIS KE+++ V+E
Sbjct: 178 -----------SPEMSNVDM-RVAENLMTWRDIALCKFTGCNLHMAHISTKEAIKYVKEA 225
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K+N ++VTCEVTPHHL ED+ +++NPP+R RED +ALI G+ DGT+D+IATD
Sbjct: 226 KENEVKVTCEVTPHHLALVGEDV------YRVNPPIREREDVDALIKGIKDGTVDVIATD 279
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPHT E+K +K S GI G ET+F YTK V+ + SL L +LMS+ A+I +
Sbjct: 280 HAPHTKEDK----KKGSPGISGIETSFPVCYTKLVREENISLNKLSELMSKRPAEIMGVN 335
Query: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G++ D+V++DL+K+ TIN +F SKG+NTP+ ++V G V+TI G++ Y
Sbjct: 336 KGQITLGFEGDLVLVDLDKQYTINSNDFESKGKNTPFDGKEVWGDVVMTIKGGRVVY 392
>gi|56417026|ref|YP_154100.1| dihydroorotase [Anaplasma marginale str. St. Maries]
gi|56388258|gb|AAV86845.1| dihydroorotase [Anaplasma marginale str. St. Maries]
Length = 454
Score = 269 bits (688), Expect = 3e-70, Method: Composition-based stats.
Identities = 156/395 (39%), Positives = 222/395 (56%), Gaps = 7/395 (1%)
Query: 27 EKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVM 86
E +++ + ID R + G +D HVH REPG KET+ T SR+AA GG TTV+
Sbjct: 62 EHKADDFQSSANEVIDCGGRVLMPGIVDIHVHLREPGGEHKETIDTGSRSAAAGGVTTVV 121
Query: 87 TMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP-YGAITKEEYGRELSDMEDIADK-VFAF 144
PN +P DSV + K L++ +S I YG+ITK L DM + + F
Sbjct: 122 CQPNTSPHIDSV-MVAKYLKMRALESSCVNIEFYGSITKP--CGSLCDMRALKEAGALGF 178
Query: 145 TDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSIC 204
TDDG V +A M A S L + H ED L GG ++EGK S ELG+KGI +
Sbjct: 179 TDDGSPVMNALSMKRAFECASTLGVVVAQHAEDCHLSDGGCINEGKVSQELGLKGISDLS 238
Query: 205 ESTQIARDI-LLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDI 263
ES + RDI LL E YHV H+S K+++ +R K + VTCEVTPHH ++ +
Sbjct: 239 ESIMVGRDIELLREVPGARYHVLHVSTKKAIDLIRSAKNEGLPVTCEVTPHHFALTEDAV 298
Query: 264 KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGS 323
+E M KMNPPLR EDR ++ G++DGTID IATDHAPH+ ++K I +FG+VG
Sbjct: 299 REHGTMAKMNPPLRTEEDRLCMVEGLVDGTIDCIATDHAPHSCQDKALPISSCAFGVVGL 358
Query: 324 ETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITI 383
ET + + LE+L KL ++ + I +P G++ + AD+V++DL+ E T+
Sbjct: 359 ETMLPLSLELYHSGKMGLLEVLSKL-TDKPSDIVKIPRGRIAKGLVADLVLVDLDHEWTV 417
Query: 384 NPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYI 418
+ +F SK +N+P+ V G + T+ GK Y+
Sbjct: 418 DTTKFASKSKNSPFHGRTVKGKALRTVVAGKTVYL 452
>gi|110599796|ref|ZP_01388029.1| dihydroorotase, multifunctional complex type [Geobacter sp. FRC-32]
gi|110549446|gb|EAT62639.1| dihydroorotase, multifunctional complex type [Geobacter sp. FRC-32]
Length = 425
Score = 269 bits (687), Expect = 3e-70, Method: Composition-based stats.
Identities = 151/405 (37%), Positives = 229/405 (56%), Gaps = 3/405 (0%)
Query: 15 KKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
+ +D+L+ +I+++ + + D ID VT G ID HVH R+PG KE V T
Sbjct: 19 ETLDLLVVAGRIKELGKGLKAPADAEVIDAAGLLVTPGLIDMHVHLRDPGLEYKEDVITG 78
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSD 133
+ AAA GGFT+V MPN PV D+ + + K ++++ P GAIT+ G L++
Sbjct: 79 TMAAAAGGFTSVACMPNTKPVNDNKAITSYIVNKAKAEALVNVFPVGAITQGSKGENLAE 138
Query: 134 MEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRS 192
M ++ + A +DDGR V +A +M A+ + ++AH E+ +L+ G M+EG +
Sbjct: 139 MGELKEAGCVAVSDDGRPVVNAELMRRALEYAKGMGVMVIAHSEELALVGEGVMNEGFTA 198
Query: 193 AELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVT 252
ELG+KGIP E +ARD+ LAE N H+ HIS K SVR +R+ K ++VTCE
Sbjct: 199 TELGLKGIPWAAEDVAVARDVYLAEFTNSPIHIAHISTKGSVRIIRDAKARGVQVTCETA 258
Query: 253 PHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRG 312
PH+ D+ ++ KMNPPLR ED A+ G+ DGTID IATDHAPH ++EK
Sbjct: 259 PHYFSLTDDAVRGYETNAKMNPPLREAEDVAAIKTGLADGTIDAIATDHAPHHLDEKDVE 318
Query: 313 IEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADI 372
+ GI+G ET+ L K V+ + ++ LV+ M+ A+I L G L+ + AD+
Sbjct: 319 FNVALNGIIGLETSLP-LSLKLVEEKVLDMKTLVEKMAVRPAQILGLDRGTLKTGAPADV 377
Query: 373 VVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+ID + E + E+ SK +N+P+ K+ G TI +GK+ +
Sbjct: 378 TIIDPKAEWVVEAEKLASKSKNSPFLGRKMTGAAAYTIVDGKVVH 422
>gi|3122654|sp|P96081|PYRC_THEAQ Dihydroorotase (DHOase)
gi|1684761|emb|CAA70731.1| dihydroorotase (DHOase) [Thermus aquaticus]
Length = 426
Score = 267 bits (683), Expect = 1e-69, Method: Composition-based stats.
Identities = 153/425 (36%), Positives = 236/425 (55%), Gaps = 12/425 (2%)
Query: 1 MLLKNCKILKN-GKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
+L++N +++ G+ +D+LI + +I + + +D F+ GF+D H H
Sbjct: 2 ILIRNVRLVDAMGERGPLDVLIGEGRILSLEGG---EAKQVVDGTGCFLAPGFLDLHAHL 58
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG KE +++ AA RGG+T +++MPN NP D+ E + E K + R P
Sbjct: 59 REPGEEVKEDLFSGLLAAVRGGYTDLVSMPNTNPPVDTPEAVRALKEKAKALGLARLHPA 118
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
A+T+++ G+ L+ + + TDDGR + A V+ +LM + L + H ED
Sbjct: 119 AALTEKQEGKTLTPAGLLQEAGAVLLTDDGRTNEDAGVLAAGLLMAAPLGLPVAVHAEDA 178
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDI------LLAEAANCHYHVCHISAKE 232
L R G M++G + LG+ G P E+ +IARD+ L A HV H+S K
Sbjct: 179 GLRRNGVMNDGPLADLLGLPGNPPEAEAARIARDLEVLRYALRRSPATPRLHVQHLSTKR 238
Query: 233 SVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDG 292
+ VRE K+ + VT E TPHHL +E ++ + ++K+ PPLRG EDR AL+ G+LDG
Sbjct: 239 GLELVREAKRAGLPVTAEATPHHLTLTEEALRTFDPLFKVAPPLRGEEDREALLEGLLDG 298
Query: 293 TIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSEN 352
T+D IATDHAPHT EK + ++ FGI E AF LYT+ F L LV+L ++
Sbjct: 299 TLDAIATDHAPHTQAEKEMDLLRAPFGIPSLEVAFPLLYTELHLKRGFPLRRLVELFTDG 358
Query: 353 VAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISN 412
++ LP LEE + A +V++D KE ++P+ F SK R +P+ ++ G PVLT+
Sbjct: 359 PRRVLGLPPLHLEEGTEASLVLLD-PKERPVDPQGFASKARFSPWTGWRLGGWPVLTLVE 417
Query: 413 GKIAY 417
G+I +
Sbjct: 418 GRIVH 422
>gi|114778473|ref|ZP_01453317.1| dihydroorotase, multifunctional complex type [Mariprofundus
ferrooxydans PV-1]
gi|114551198|gb|EAU53757.1| dihydroorotase, multifunctional complex type [Mariprofundus
ferrooxydans PV-1]
Length = 430
Score = 265 bits (677), Expect = 4e-69, Method: Composition-based stats.
Identities = 146/422 (34%), Positives = 237/422 (56%), Gaps = 4/422 (0%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN I+ NG D+ I D +I I + +D + V G ID HVH
Sbjct: 5 LLIKNGHIIDPANGIDTVADLWINDGRIAGIGSFEGEQPDQLVDATGKVVCPGLIDMHVH 64
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
REPG KE + + SRAA GG T++ MPN P D + + + ++ P
Sbjct: 65 LREPGQEWKEDIESGSRAAVAGGVTSMCCMPNTGPHIDHAGIALQIVARARQVNLCNVHP 124
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
GA+TK G+EL++M +++ AF+DDG + A VM +A+ + ++ H E+
Sbjct: 125 IGAVTKNLDGKELTEMRELSRAGCVAFSDDGLPIWHAGVMRKALEYSASFGFMVIQHAEE 184
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
+L +GGA++EG S +LG++G+P+ E + IARDI+L + A+ YHV HIS +V V
Sbjct: 185 KALTKGGAVNEGWISTQLGVEGMPAAGEDSMIARDIMLTKLADARYHVAHISTAGAVELV 244
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R+ +K ++VT E PHH ++++ N KM+PPLR DR A++ G+ DGTI++I
Sbjct: 245 RQARKQGLKVTTEAAPHHFALTEDEVLGYNSDAKMSPPLRTEADRLAVVEGLRDGTIEVI 304
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH ++K G+ ++FGIVG ET + + V+ + S+ ++ M+ N A++
Sbjct: 305 ATDHAPHHEDDKRCGLSCAAFGIVGLETMLP-VSLELVRDGVLSMSDMIAKMTCNPARLL 363
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L G L + AD+ + D + ++ + +SKG+NTP+ +++ G TI G++ +
Sbjct: 364 GLDSGTLSTGADADVTIFDADATWMLDRNKLVSKGKNTPWHGKQMTGRVTHTIKAGRVVF 423
Query: 418 ID 419
D
Sbjct: 424 SD 425
>gi|118746284|ref|ZP_01594231.1| dihydroorotase, multifunctional complex type [Geobacter lovleyi SZ]
gi|118680796|gb|EAV87247.1| dihydroorotase, multifunctional complex type [Geobacter lovleyi SZ]
Length = 425
Score = 265 bits (677), Expect = 4e-69, Method: Composition-based stats.
Identities = 146/421 (34%), Positives = 235/421 (55%), Gaps = 5/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVT-DENTIDVKDRFVTAGFIDAHV 57
+L+K +++ G +D+++++ +++I + + + TID ++V G ID HV
Sbjct: 3 LLIKGGRVIDPSQGIDDTLDVVVENGLVKEIGKGLATSAGAETIDASGKYVVPGLIDMHV 62
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H R+PG KE + + +RAA GGFT+V MPN P D+ + + K +
Sbjct: 63 HLRDPGLEYKEDIISGTRAAVAGGFTSVCCMPNTKPAIDNKAIASYIINKAKTEGACNVF 122
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P G IT+ +G L++M ++ + A +DDG+ V+++ +M A+ + + +++H E
Sbjct: 123 PVGTITQGMHGDRLAEMGELKESGCVAVSDDGKPVKNSELMRRALQYAAGIGIMVISHAE 182
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
+ L+ G M+EG S ELG+KGIP + E AR+I+LAE H+ H+S K +VR
Sbjct: 183 ELELVGEGVMNEGFTSTELGLKGIPRVAEDIATAREIMLAEYVGAPIHIAHVSTKGAVRI 242
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
+RE K ++VTCE PH+ D+ ++ N KMNPPLR +D A+ AG+ DGTID
Sbjct: 243 IREAKGRGVKVTCETAPHYFTLTDDAVRGYNTNAKMNPPLREADDLAAIKAGLKDGTIDC 302
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPH ++EK ++ GIVG ET+ L K V + +L L++ MS +++
Sbjct: 303 IATDHAPHHLDEKDVEFNEAMNGIVGLETSLP-LSLKLVDEGVLNLSQLIEKMSCKPSEL 361
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
L G L+ + ADI VID K+ T+ SK +N+P+ + G T+ GKI
Sbjct: 362 LGLGRGSLKAGNVADITVIDPAKQWTVTESALASKSKNSPWLGATMAGAAACTVVGGKIV 421
Query: 417 Y 417
+
Sbjct: 422 F 422
>gi|55980750|ref|YP_144047.1| dihydroorotase [Thermus thermophilus HB8]
gi|55772163|dbj|BAD70604.1| dihydroorotase (PyrC) [Thermus thermophilus HB8]
Length = 426
Score = 265 bits (676), Expect = 5e-69, Method: Composition-based stats.
Identities = 152/425 (35%), Positives = 235/425 (55%), Gaps = 12/425 (2%)
Query: 1 MLLKNCKILK-NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
+L++N +++ G+ D+LI + +I + + +D F+ GF+D H H
Sbjct: 2 ILIRNVRLVDARGERGPADVLIGEGRILSLEGG---EAKQVVDGTGCFLAPGFLDLHAHL 58
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG KE +++ AA RGG+T +++MPN P D+ E + E K + R P
Sbjct: 59 REPGEEVKEDLFSGLLAAVRGGYTDLVSMPNTKPPVDTPEAVRALKEKAKALGLARLHPA 118
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
A+T+++ G+ L+ + + TDDGR + A V+ +LM + L + H ED
Sbjct: 119 AALTEKQEGKTLTPAGLLREAGAVLLTDDGRTNEDAGVLAAGLLMAAPLGLPVAVHAEDA 178
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDI------LLAEAANCHYHVCHISAKE 232
L R G M++G + LG+ G P E+ +IARD+ L A HV H+S K
Sbjct: 179 GLRRNGVMNDGPLADLLGLPGNPPEAEAARIARDLEVLRYALRRSPATPRLHVQHLSTKR 238
Query: 233 SVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDG 292
+ VRE K+ + VT E TPHHL +E ++ + ++K+ PPLRG EDR AL+ G+LDG
Sbjct: 239 GLELVREAKRAGLPVTAEATPHHLTLTEEALRTFDPLFKVAPPLRGEEDREALLEGLLDG 298
Query: 293 TIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSEN 352
T+D IATDHAPHT+ EK + + ++ FGI E AF LYT+ F L+ LV+L ++
Sbjct: 299 TLDAIATDHAPHTLAEKEKDLLRAPFGIPSLEVAFPLLYTELHLKRGFPLQRLVELFTDG 358
Query: 353 VAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISN 412
++ LP LEE + A +V++ KE ++P F SK R +P+A + G PVLT+
Sbjct: 359 PRRVLGLPPLHLEEGAEASLVLLS-PKERPVDPSAFASKARYSPWAGWVLGGWPVLTLVA 417
Query: 413 GKIAY 417
G+I +
Sbjct: 418 GRIVH 422
>gi|28201871|sp|Q9CGM7|PYRC_LACLA Dihydroorotase (DHOase)
Length = 423
Score = 264 bits (675), Expect = 8e-69, Method: Composition-based stats.
Identities = 159/421 (37%), Positives = 242/421 (57%), Gaps = 7/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + +DILI++DKI KI N+ V + +D + V G ID HVH
Sbjct: 3 LLIKNGRLVDPKSNRDEVLDILIENDKIVKIGLNLSVENAEIVDARGLVVAPGLIDVHVH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEII-KNDSVIRAI 117
+REPG + KET+++ +++AA GGFT V+ M N P+ + + L + LEI K D I A+
Sbjct: 63 FREPGQTHKETIHSGAKSAAAGGFTRVVMMANTKPILSTPKVLTETLEIADKEDIKIDAV 122
Query: 118 PYGAITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
G+IT++ G L+D ++ I F+DDG + A V+ +A+ + I H E
Sbjct: 123 --GSITQDFDGEHLTDFDELIKAGAIGFSDDGIPLTDAGVLRKALQKAKLTDSLISIHEE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D +LI +++G+ + + G G P++ E + +ARD ++A H+ H+SA ESV
Sbjct: 181 DPNLIGTLGVNDGEVAHKCGFTGAPTVSEYSMMARDSMIAYETGARLHIQHLSAGESVEV 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
VR K ++T EVTP H ++ I E K+NPPLR D +I G+ DGTID+
Sbjct: 241 VRFAKNLGAKITAEVTPQHFSITEQMIFEQGTNAKLNPPLRSTTDIGKIIEGLKDGTIDV 300
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPHT EEK ++K+ G++G ET+ T V +L L+ M+ N AK+
Sbjct: 301 IATDHAPHTREEKNVSLDKAPSGMIGLETSLQLGLTNLVAKGHLTLSELLTKMTVNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN AD+V+ D E + + E F SK N+P+ +KV G TI +GKI
Sbjct: 361 YNFDAGYLAENGPADLVIFDAENDYQVG-ETFDSKATNSPFIKQKVQGQVKYTICDGKIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|46198734|ref|YP_004401.1| dihydroorotase [Thermus thermophilus HB27]
gi|46196357|gb|AAS80774.1| dihydroorotase [Thermus thermophilus HB27]
Length = 426
Score = 263 bits (673), Expect = 1e-68, Method: Composition-based stats.
Identities = 151/425 (35%), Positives = 234/425 (55%), Gaps = 12/425 (2%)
Query: 1 MLLKNCKILK-NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
+L++N +++ G+ D+LI + +I + + +D F+ GF+D H H
Sbjct: 2 ILIRNVRLVDARGERGPADVLIGEGRILSLEGG---EAKQVVDGTGCFLAPGFLDLHAHL 58
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG KE +++ AA RGG+T +++MPN P D+ E + E K + R P
Sbjct: 59 REPGEEVKEDLFSGLLAAVRGGYTDLVSMPNTKPPVDTPEAVRALKEKAKALGLARLHPA 118
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
A+T+++ G+ L+ + + TDDGR + A V+ +LM + L + H ED
Sbjct: 119 AALTEKQEGKTLTPAGLLQEAGAVLLTDDGRTNEDAGVLAAGLLMAAPLGLPVAVHAEDA 178
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILL------AEAANCHYHVCHISAKE 232
L R G M++G + LG+ G P E+ +IARD+ + A HV H+S K
Sbjct: 179 GLRRNGVMNDGPLADLLGLPGNPPEAEAARIARDLEVLRYASRRSPATPRLHVQHLSTKR 238
Query: 233 SVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDG 292
+ +RE K+ + VT E TPHHL +E ++ N ++K+ PPLRG EDR AL+ G+LDG
Sbjct: 239 GLELIREAKRAGLPVTAEATPHHLTLTEEALRAFNPLFKVAPPLRGEEDREALLEGLLDG 298
Query: 293 TIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSEN 352
T+D IATDHAPHT+ EK + + ++ FGI E AF LYT+ F L LV+L ++
Sbjct: 299 TLDAIATDHAPHTLAEKEKDLLRAPFGIPSLEVAFPLLYTELHLKRGFPLPRLVELFTDG 358
Query: 353 VAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISN 412
++ LP LEE + A +V++ KE ++P F SK R +P+A + G PVLT+
Sbjct: 359 PRRVLGLPPLHLEEGAEASLVLLS-PKERPVDPSAFASKARYSPWAGWVLGGWPVLTLVA 417
Query: 413 GKIAY 417
G+I +
Sbjct: 418 GRIVH 422
>gi|57239363|ref|YP_180499.1| dihydroorotase [Ehrlichia ruminantium str. Welgevonden]
gi|57161442|emb|CAH58367.1| dihydroorotase [Ehrlichia ruminantium str. Welgevonden]
Length = 449
Score = 263 bits (672), Expect = 1e-68, Method: Composition-based stats.
Identities = 158/410 (38%), Positives = 235/410 (57%), Gaps = 12/410 (2%)
Query: 16 KVDILIKDDKIEKISENIDVTDENT-----IDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
K +L K DKI N+ T +D K + + G ID HVH+REPG KET+
Sbjct: 36 KGSLLTKGDKIVDFGPNLFADGIPTGICEVVDCKHKILMPGLIDIHVHFREPGQEHKETI 95
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP-YGAITKEEYGR 129
T S++AA GG TTV+ PN P SV + K +++ ++ I Y +ITK +
Sbjct: 96 ETGSKSAAAGGITTVVCQPNTIPTISSV-IIAKYIKMRALETAYVNIEFYASITKPD--N 152
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
LSDM + + FTDDG V ++ +M +A+ S L+ I H ED +L G ++E
Sbjct: 153 SLSDMALLKEAGAVGFTDDGMPVMNSLIMRQALSYSSMLDTVIAQHAEDLNLSNNGCINE 212
Query: 189 GKRSAELGIKGIPSICESTQIARDI-LLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
GK S ELG+KG+P I ES + RDI +L N HYHV HIS+K S+ +++ K ++V
Sbjct: 213 GKVSYELGLKGMPDISESIIVNRDIAILNTLKNVHYHVLHISSKSSLDIIKQAKNQGLKV 272
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
TCEVTPHHL ++D+ + + KMNPPLR DR ++I G+ +G ID IATDHAPH +
Sbjct: 273 TCEVTPHHLTLTEQDVIQHSTFAKMNPPLRTESDRISMIEGLKNGIIDCIATDHAPHDLG 332
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEEN 367
K ++ ++FGIVG ET + + L L+ ++ A I +P G++++
Sbjct: 333 SKELPLDTAAFGIVGLETMLP-ISLELYHNGTMPLIDLLATLTYKPADIIRVPRGRIKKG 391
Query: 368 SFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
AD++++DL+ E TI+ +F SK +N+P+ N KV G + T+ +GK Y
Sbjct: 392 FTADLILLDLDHEWTIDISKFASKSKNSPFHNRKVKGKVLRTVVSGKTTY 441
>gi|58617384|ref|YP_196583.1| Dihydroorotase [Ehrlichia ruminantium str. Gardel]
gi|58416996|emb|CAI28109.1| Dihydroorotase [Ehrlichia ruminantium str. Gardel]
Length = 449
Score = 263 bits (672), Expect = 2e-68, Method: Composition-based stats.
Identities = 158/410 (38%), Positives = 234/410 (57%), Gaps = 12/410 (2%)
Query: 16 KVDILIKDDKI-----EKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
K +L K DKI ++ I +D K + + G ID HVH+REPG KET+
Sbjct: 36 KGSLLTKGDKIVDFGPSLFADGIPTGICEVVDCKHKILMPGLIDIHVHFREPGQEHKETI 95
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP-YGAITKEEYGR 129
T S++AA GG TTV+ PN P SV + K +++ ++ I Y +ITK +
Sbjct: 96 ETGSKSAAAGGITTVVCQPNTIPTISSV-IIAKYIKMRALETAYVNIEFYASITKPD--N 152
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
LSDM + + FTDDG V ++ +M +A+ S L+ I H ED +L G ++E
Sbjct: 153 SLSDMALLKEAGAVGFTDDGMPVMNSLIMRQALSYSSMLDTVIAQHAEDLNLSNNGCINE 212
Query: 189 GKRSAELGIKGIPSICESTQIARDI-LLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
GK S ELG+KG+P I ES + RDI +L N HYHV HIS+K S+ +++ K ++V
Sbjct: 213 GKVSYELGLKGMPDISESIIVNRDIAILNTLKNVHYHVLHISSKSSLDIIKQAKNQGLKV 272
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
TCEVTPHHL ++D+ + KMNPPLR DR ++I G+ +G ID IATDHAPH +
Sbjct: 273 TCEVTPHHLTLTEQDVIQHGTFAKMNPPLRTESDRISMIEGLKNGIIDCIATDHAPHDLG 332
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEEN 367
K ++ ++FGIVG ET + + L L+ ++ A I +P G++++
Sbjct: 333 SKELPLDTAAFGIVGLETMLP-ISLELYHNGTMPLIDLLATLTYKPADIIRVPRGRIKKG 391
Query: 368 SFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
AD++++DL+ E TI+ +F SK +N+P+ N KV G + TI +GK Y
Sbjct: 392 FTADLILLDLDHEWTIDISKFASKSKNSPFHNRKVKGKVLRTIVSGKTTY 441
>gi|58579330|ref|YP_197542.1| Dihydroorotase [Ehrlichia ruminantium str. Welgevonden]
gi|58417956|emb|CAI27160.1| Dihydroorotase [Ehrlichia ruminantium str. Welgevonden]
Length = 449
Score = 263 bits (672), Expect = 2e-68, Method: Composition-based stats.
Identities = 158/410 (38%), Positives = 234/410 (57%), Gaps = 12/410 (2%)
Query: 16 KVDILIKDDKIEKISENIDVTDENT-----IDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
K +L K DKI N+ T +D K + + G ID HVH+REPG KET+
Sbjct: 36 KGSLLTKGDKIVDFGPNLFADGIPTGICEVVDCKHKILMPGLIDIHVHFREPGQEHKETI 95
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP-YGAITKEEYGR 129
T S++AA GG TTV+ PN P SV + K +++ ++ I Y +ITK +
Sbjct: 96 ETGSKSAAAGGITTVVCQPNTIPTISSV-IIAKYIKMRALETAYVNIEFYASITKPD--N 152
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
LSDM + + FTDDG V ++ +M +A+ S L+ I H ED +L G ++E
Sbjct: 153 SLSDMALLKEAGAVGFTDDGMPVMNSLIMRQALSYSSMLDTVIAQHAEDLNLSNNGCINE 212
Query: 189 GKRSAELGIKGIPSICESTQIARDI-LLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
GK S ELG+KG+P I ES + RDI +L N HYHV HIS+K S+ +++ K ++V
Sbjct: 213 GKVSYELGLKGMPDISESIIVNRDIAILNTLKNVHYHVLHISSKSSLDIIKQAKNQGLKV 272
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
TCEVTPHHL ++D+ + KMNPPLR DR ++I G+ +G ID IATDHAPH +
Sbjct: 273 TCEVTPHHLTLTEQDVIQHGTFAKMNPPLRTESDRISMIEGLKNGIIDCIATDHAPHDLG 332
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEEN 367
K ++ ++FGIVG ET + + L L+ ++ A I +P G++++
Sbjct: 333 SKELPLDTAAFGIVGLETMLP-ISLELYHNGTMPLIDLLATLTYKPADIIRVPRGRIKKG 391
Query: 368 SFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
AD++++DL+ E TI+ +F SK +N+P+ N KV G + T+ +GK Y
Sbjct: 392 FTADLILLDLDHEWTIDISKFASKSKNSPFHNRKVKGKVLRTVVSGKTTY 441
>gi|15673051|ref|NP_267225.1| dihydroorotase [Lactococcus lactis subsp. lactis Il1403]
gi|12724023|gb|AAK05167.1|AE006339_10 dihydroorotase (EC 3.5.2.3) [Lactococcus lactis subsp. lactis
Il1403]
Length = 441
Score = 263 bits (672), Expect = 2e-68, Method: Composition-based stats.
Identities = 159/421 (37%), Positives = 242/421 (57%), Gaps = 7/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + +DILI++DKI KI N+ V + +D + V G ID HVH
Sbjct: 21 LLIKNGRLVDPKSNRDEVLDILIENDKIVKIGLNLSVENAEIVDARGLVVAPGLIDVHVH 80
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEII-KNDSVIRAI 117
+REPG + KET+++ +++AA GGFT V+ M N P+ + + L + LEI K D I A+
Sbjct: 81 FREPGQTHKETIHSGAKSAAAGGFTRVVMMANTKPILSTPKVLTETLEIADKEDIKIDAV 140
Query: 118 PYGAITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
G+IT++ G L+D ++ I F+DDG + A V+ +A+ + I H E
Sbjct: 141 --GSITQDFDGEHLTDFDELIKAGAIGFSDDGIPLTDAGVLRKALQKAKLTDSLISIHEE 198
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D +LI +++G+ + + G G P++ E + +ARD ++A H+ H+SA ESV
Sbjct: 199 DPNLIGTLGVNDGEVAHKCGFTGAPTVSEYSMMARDSMIAYETGARLHIQHLSAGESVEV 258
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
VR K ++T EVTP H ++ I E K+NPPLR D +I G+ DGTID+
Sbjct: 259 VRFAKNLGAKITAEVTPQHFSITEQMIFEQGTNAKLNPPLRSTTDIGKIIEGLKDGTIDV 318
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPHT EEK ++K+ G++G ET+ T V +L L+ M+ N AK+
Sbjct: 319 IATDHAPHTREEKNVSLDKAPSGMIGLETSLQLGLTNLVAKGHLTLSELLTKMTVNPAKL 378
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN AD+V+ D E + + E F SK N+P+ +KV G TI +GKI
Sbjct: 379 YNFDAGYLAENGPADLVIFDAENDYQVG-ETFDSKATNSPFIKQKVQGQVKYTICDGKIV 437
Query: 417 Y 417
Y
Sbjct: 438 Y 438
>gi|28210638|ref|NP_781582.1| dihydroorotase [Clostridium tetani E88]
gi|28203076|gb|AAO35519.1| dihydroorotase [Clostridium tetani E88]
Length = 421
Score = 263 bits (671), Expect = 2e-68, Method: Composition-based stats.
Identities = 165/424 (38%), Positives = 244/424 (57%), Gaps = 9/424 (2%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTD--ENTIDVKDRFVTAGFIDAH 56
+L+K+ +++ K K + +D++IKD+KI KI + +D E ID K + V G ID H
Sbjct: 2 ILIKDGRLIDPKTNKDEILDLIIKDNKIYKIGK-FQSSDKYETVIDAKGKIVAPGLIDVH 60
Query: 57 VHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRA 116
VH+R+PGF+ KE + T S +AARGGFTTV+ M N NP+ D+ ETLN ++ S I
Sbjct: 61 VHFRDPGFTYKEDIQTGSDSAARGGFTTVVCMANTNPIVDNEETLN-YIKKESEKSKINV 119
Query: 117 IPYGAITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHC 175
+ GAITK G+EL DME + F+DDG + + ++ EAM+ +LN + H
Sbjct: 120 LQVGAITKGFKGKELVDMEYLKSIGAVGFSDDGVPIMDSKLVMEAMIKAKELNVPLSFHE 179
Query: 176 EDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVR 235
ED +LI +++GK S +L KG P++ E T +ARD +LA ++ HIS+ SV
Sbjct: 180 EDPALIGSSGINQGKISDKLCGKGAPNVAEDTMVARDCILALKTGAKVNIQHISSGISVD 239
Query: 236 AVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTID 295
VR K V E TPHH +E + E KMNPPLR ED+ +I G+ D I+
Sbjct: 240 IVRFVKSLGANVVAEATPHHFSLTEEAVLEHKTYAKMNPPLRTEEDKYKIIQGLKDDIIE 299
Query: 296 IIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IIATDHAPH++EEK + + K+ GI+G ET+ + V+ ++ L++ M+ N AK
Sbjct: 300 IIATDHAPHSIEEKEKELTKAPSGIIGLETSLALGISNLVRKGHLTIMKLIEKMTINPAK 359
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
++NL G + E + ADIV+ D + ++ F SK N+P+ + + G TI G I
Sbjct: 360 LYNLDTGFIAEGAIADIVIFDPSENWVVS--GFASKSSNSPFKGQNLYGKIKYTICKGNI 417
Query: 416 AYID 419
Y D
Sbjct: 418 VYKD 421
>gi|145622709|ref|ZP_01778665.1| dihydroorotase, multifunctional complex type [Petrotoga mobilis
SJ95]
gi|144946921|gb|EDJ81957.1| dihydroorotase, multifunctional complex type [Petrotoga mobilis
SJ95]
Length = 398
Score = 263 bits (671), Expect = 2e-68, Method: Composition-based stats.
Identities = 156/416 (37%), Positives = 235/416 (56%), Gaps = 28/416 (6%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
++KNC+I+ K D+ IKD KI+ +++ D TID + V F+D H H+R+
Sbjct: 1 MIKNCRIVDEEKDLFGDLYIKDGKIDNYGRSLNY-DTYTIDAQGLIVMPAFVDMHAHFRD 59
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG++ KE +++ S AA +GG+T V M N NP+ +E + L K ++I +
Sbjct: 60 PGYTYKEDLHSGSLAALKGGYTCVNLMGNTNPICSDMEVVKYVLNKAKELNLIDIHQTVS 119
Query: 122 ITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLI 181
ITK G+ L ++ I + V +DDG+GVQS MY AM+ + I+AH EDN ++
Sbjct: 120 ITKNFDGKSLEHLDYIDNNVKFISDDGKGVQSNLTMYLAMIKAKEKGLTIIAHEEDNEIV 179
Query: 182 RGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGK 241
+ E+ RDI LA+ H+ H+S KE++ +R+ K
Sbjct: 180 TIDT----------------RLSENLMTFRDIYLAKLTGAWLHLAHVSTKEAIEGIRKAK 223
Query: 242 KNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDH 301
+ +TCEVTPHHL + D +K+NPP+R +ED +I G+ DGT+DIIATDH
Sbjct: 224 REIQNLTCEVTPHHLALYNYD-------YKVNPPIREKEDVLEIINGIKDGTVDIIATDH 276
Query: 302 APHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPY 361
APH+ ++K EK + GI G ETAF YTK VK++ SL L +LMS A++ +
Sbjct: 277 APHSTQDK----EKGAPGISGLETAFPVCYTKLVKSEEISLNRLSQLMSSKPAQMLGVKK 332
Query: 362 GKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
GK++ D+V++DLEK++ IN +EFLSKG+NTP+ + G + TI G+I Y
Sbjct: 333 GKIQTGYDGDVVIVDLEKKVKINKDEFLSKGKNTPFDGMEFYGEVIATIRKGEIKY 388
>gi|39996374|ref|NP_952325.1| dihydroorotase, multifunctional complex type [Geobacter
sulfurreducens PCA]
gi|39983254|gb|AAR34648.1| dihydroorotase, multifunctional complex type [Geobacter
sulfurreducens PCA]
Length = 425
Score = 262 bits (670), Expect = 2e-68, Method: Composition-based stats.
Identities = 151/421 (35%), Positives = 229/421 (54%), Gaps = 5/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHV 57
+L+K +++ G + +DIL+++ I+++ + + +D VT G ID HV
Sbjct: 3 LLIKGGRVIDPSQGIDEVLDILVENGAIKELGKGLAAPAGAGVVDAAGLIVTPGLIDMHV 62
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H R+PG KE + T +RAAA GGFT+V MPN PV D+ + + K + ++
Sbjct: 63 HLRDPGLEYKEDIVTGTRAAAAGGFTSVACMPNTKPVNDNKAVTSYIVAKAKAEGLVNVF 122
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P G+IT+ G L++M D+ + A +DDGR V S+ +M A+ + +++H E
Sbjct: 123 PVGSITQGSKGDALAEMGDLKEAGCVAVSDDGRPVTSSELMRRALEYAKGMGIMVISHAE 182
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D SL+ G M+EG S ELG+KGIP E ARD+ LAE N H+ H+S S+R
Sbjct: 183 DLSLVGEGVMNEGFVSTELGLKGIPWAAEDAATARDVYLAEFTNSPLHIAHVSTMGSLRI 242
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
+R K ++VTCE PH+ D+ ++ N KMNPPLR +D A+ + DGTID
Sbjct: 243 IRNAKARGVKVTCETAPHYFSLTDDAVRGYNTNAKMNPPLRTADDLAAVKEALKDGTIDA 302
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPH ++EK + GI+G ET+ L K V+ + +L LV+ M+ N A I
Sbjct: 303 IATDHAPHHLDEKDVEFNVALNGIIGLETSLP-LSLKLVEEGVLTLPALVEKMACNPAAI 361
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L + + ADI VID T+ SK +N+P+ ++ G TI G +
Sbjct: 362 LGIDRGTLRQGAVADITVIDPAAVWTVEAGALASKSKNSPFLGWEMKGAAAYTIVGGTVV 421
Query: 417 Y 417
+
Sbjct: 422 H 422
>gi|15893810|ref|NP_347159.1| dihydroorotase [Clostridium acetobutylicum ATCC 824]
gi|23821990|sp|Q97LN7|PYRC_CLOAB Dihydroorotase (DHOase)
gi|15023383|gb|AAK78499.1|AE007567_1 Dihydroorotase [Clostridium acetobutylicum ATCC 824]
Length = 424
Score = 262 bits (670), Expect = 3e-68, Method: Composition-based stats.
Identities = 157/413 (38%), Positives = 242/413 (58%), Gaps = 6/413 (1%)
Query: 10 KNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWREPGFSKKE 68
+ GKF DILI + + +IS++I + D+ ID +D V+ GFID H H+R+PGF++KE
Sbjct: 16 REGKF---DILIDGENVVRISQDIGIDDDIEVIDAEDCIVSPGFIDIHSHFRDPGFTEKE 72
Query: 69 TVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYG 128
+ T +RAAARGG+TTV+ M N NPV D+VETL ++ K + I + G ITK G
Sbjct: 73 DIITGARAAARGGYTTVICMANTNPVVDNVETLRYIVDKAKT-AKIEVLQVGTITKGMQG 131
Query: 129 RELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
EL DME + + F+DDG+ + + ++ EAM +L+ + H ED L+ ++
Sbjct: 132 VELVDMEALKEAGAVGFSDDGKPIMDSRLVLEAMQKARELDVPLSFHEEDPKLVYESGIN 191
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
GK + +L + G E+ ARD LA ++ ++ HIS+K S+ ++ K+ +
Sbjct: 192 GGKVAEKLNMMGALEEAETVLTARDAALAVSSGAKTNIQHISSKISLGIIKLAKEMGANI 251
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
E TP H +E+I K+NPPLR +DR A++A + D TI +IATDHAPHT +
Sbjct: 252 IAEATPQHFSITEEEILNCGTNAKVNPPLRREDDRKAIVAALKDDTIQVIATDHAPHTKD 311
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEEN 367
EK R +++ G++G ETA + T VKT + ++ ++ N A+ +NL G ++E
Sbjct: 312 EKAREFKEAPSGMIGLETALSLAVTNLVKTGDLTYRDMISKLTINPARFYNLDRGYIKEG 371
Query: 368 SFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDK 420
ADIV+ D +++ T+ EEF SK N+P+ +++ G TI NGKI Y DK
Sbjct: 372 HRADIVIFDPDEKYTVKEEEFQSKASNSPFIGKELFGKVKTTIYNGKIVYEDK 424
>gi|118580940|ref|YP_902190.1| dihydroorotase, multifunctional complex type [Pelobacter
propionicus DSM 2379]
gi|118503650|gb|ABL00133.1| dihydroorotase, multifunctional complex type [Pelobacter
propionicus DSM 2379]
Length = 424
Score = 262 bits (669), Expect = 4e-68, Method: Composition-based stats.
Identities = 146/421 (34%), Positives = 230/421 (54%), Gaps = 5/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHV 57
+L++N +++ G +++D+L+++ + ++ + +D V G +D HV
Sbjct: 3 LLIQNGRVIDPSQGLDEELDLLVENGLVREMGRGLTAPAGVEIVDAAGCCVVPGLVDMHV 62
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H REPG KE + + SRAA GGFT++ MPN PV D+ + + +
Sbjct: 63 HLREPGLEYKEDIESGSRAAVAGGFTSIACMPNTKPVIDNKALARYVIARGREAGLCNVF 122
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P G +T G L++M ++ + A +DDGR V +A +M A+ + +++H E
Sbjct: 123 PVGCLTAGSKGERLAEMGELKEAGCVAVSDDGRPVVNAELMRRALEYARGMQIPVISHAE 182
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D SL+ G M+EG S ELG+KGIP + E IARD++LAE N H+ H+S +VR
Sbjct: 183 DLSLVGEGVMNEGFTSTELGLKGIPRVAEDIAIARDVMLAEYTNSPIHIAHVSTSGAVRI 242
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
+R K +RVTCE PH+ D+ ++ N KMNPPLR +D A+ AG+ DGTID+
Sbjct: 243 IRNAKLRGVRVTCETAPHYFTLTDDAVRGYNTNAKMNPPLREADDVAAIRAGLSDGTIDV 302
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPH ++EK ++ GI+G ET+ L V+ + ++ LV+ MS + I
Sbjct: 303 IATDHAPHHLDEKDVEFNVAANGIIGLETSLP-LSLALVEQGVLTMSQLVERMSCCPSLI 361
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
L G L + + ADI +ID + ++ SK NTP+ +++ G V TI G++
Sbjct: 362 LGLERGTLAKGAVADITLIDPTLPWVVEADKLASKSTNTPWMGQEMKGAAVATIVAGRVV 421
Query: 417 Y 417
Y
Sbjct: 422 Y 422
>gi|153892127|ref|ZP_02013073.1| dihydroorotase, multifunctional complex type [Opitutaceae bacterium
TAV2]
gi|151581800|gb|EDN45407.1| dihydroorotase, multifunctional complex type [Opitutaceae bacterium
TAV2]
Length = 433
Score = 261 bits (667), Expect = 6e-68, Method: Composition-based stats.
Identities = 153/408 (37%), Positives = 223/408 (54%), Gaps = 4/408 (0%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
D+ I D KI D ID G +D HVH+REPG + KET+ T SRAA
Sbjct: 23 DLYIVDGKIAATLSAADKKKARKIDAAGLVAAPGLVDIHVHFREPGQTHKETIETGSRAA 82
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI 137
A GGFT+V+ MPN +PV D+ T+ + I+ S I+ P G IT G+ L+ + +
Sbjct: 83 AAGGFTSVVCMPNTSPVADTAGTIQLINDSIRRTSCIKVYPTGCITTGMKGQALAPIGSL 142
Query: 138 ADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGA-MHEGKRSAEL 195
V A TDDG VQS +M A + ++ HC+D+S+ GA M+EG S L
Sbjct: 143 KRAGVVAITDDGDCVQSNELMRRACEYARMFDLPLMDHCQDHSMTNAGAVMNEGVMSTRL 202
Query: 196 GIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
G++G P+ E ++R+++LA H+ HIS+ +V +R K + VT E TPHH
Sbjct: 203 GLRGWPNAAEDIIVSRNVILATYTGARIHMQHISSHNAVDIIRRAKTRGVPVTAEGTPHH 262
Query: 256 LLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEK 315
D ++ + +KMNPPLR +DR A+I G+ DGT+DIIATDHAPHT +EK + +
Sbjct: 263 FALTDACLETYDTRFKMNPPLRTEDDRLAIIEGLRDGTLDIIATDHAPHTDDEKDKEFDY 322
Query: 316 SSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP--YGKLEENSFADIV 373
+ GI+G ET+ + + F L ++ LM+ A I NLP G L E S AD+V
Sbjct: 323 APNGIIGLETSLPISLEILHRQNKFKLATVIDLMTRKPAAIVNLPGGAGTLAEGSAADLV 382
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKE 421
+ D ++E + + SK N+P+ +K+ G T +GK+ Y K+
Sbjct: 383 LFDPDEEWLYDSNKGFSKSGNSPWHRQKLRGRVKATYVDGKLIYDGKK 430
>gi|115380674|ref|ZP_01467599.1| dihydroorotase [Stigmatella aurantiaca DW4/3-1]
gi|115362321|gb|EAU61631.1| dihydroorotase [Stigmatella aurantiaca DW4/3-1]
Length = 433
Score = 261 bits (667), Expect = 6e-68, Method: Composition-based stats.
Identities = 153/402 (38%), Positives = 217/402 (53%), Gaps = 3/402 (0%)
Query: 18 DILIKDDKIEKISEN-IDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
D+L++D I ++SE + V ++ + +V GFID HVH REPG KET+ T +A
Sbjct: 26 DVLVRDGVIAEVSEAPLSVPGAQVVEAQGHWVLPGFIDLHVHLREPGEEGKETILTGCQA 85
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDM-E 135
A GGFT V+ MPN V DS L + ++ P GAITK G E+++M E
Sbjct: 86 AVAGGFTGVVAMPNTKLVNDSSLVTELVLSRARAANLCHVYPAGAITKGLKGEEMAEMGE 145
Query: 136 DIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAEL 195
++ TDDGR V +A +M A+ + ++ H ED +L GAM EG + L
Sbjct: 146 LVSAGCVCITDDGRPVMNAGLMRRALQYARLFDLPVMVHEEDLTLSGKGAMTEGPTATRL 205
Query: 196 GIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
G+ IP E +ARD++L E H+ H+S + SVR +RE K+ + VT EVTPHH
Sbjct: 206 GLLPIPPSAEVAMVARDLVLLEETGGRLHIAHVSCEGSVRLLREAKRRGLHVTSEVTPHH 265
Query: 256 LLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEK 315
D + E + KMNPPLR R D AL + DGTI+ IATDHAPH + +K +K
Sbjct: 266 FTLDDAAVGEYDTHAKMNPPLRLRRDVEALREALADGTIEAIATDHAPHGVLDKQVEFDK 325
Query: 316 SSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVI 375
G+VG ETA L V + S V+++++ AK F LP G L+ + ADI ++
Sbjct: 326 GINGVVGLETALG-LTLALVHEGVLSARRAVEVLTDGPAKAFGLPGGHLKPGAPADIALV 384
Query: 376 DLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
D E + T++ F SK RNTP+ + G V T G+ +
Sbjct: 385 DPEAKWTVDAGRFFSKSRNTPFHGRSLKGRVVQTWVGGRCVF 426
>gi|113941598|ref|ZP_01427388.1| dihydroorotase, multifunctional complex type [Herpetosiphon
aurantiacus ATCC 23779]
gi|113896738|gb|EAU15810.1| dihydroorotase, multifunctional complex type [Herpetosiphon
aurantiacus ATCC 23779]
Length = 473
Score = 261 bits (667), Expect = 7e-68, Method: Composition-based stats.
Identities = 152/424 (35%), Positives = 220/424 (51%), Gaps = 25/424 (5%)
Query: 18 DILIKDDKIEKISENIDVTDE-----NTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYT 72
D++++++++ ++ E D ID FVT GFID H H REPGF KET+ T
Sbjct: 23 DLVLENNRVREVIELAMAPDSYGDDVEFIDASGCFVTPGFIDIHTHLREPGFEGKETIAT 82
Query: 73 ASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELS 132
AA RGG+TT+ MPN NP DS + +Q +I I +P GA+T G+ L+
Sbjct: 83 GMDAAVRGGYTTICPMPNTNPSLDSAPLIRQQFDIAARHGPIHVLPIGAVTLGREGKVLA 142
Query: 133 DMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
+ ++A+ F+DDG V A++M +A+L + ++ HCED S++RG M+EG
Sbjct: 143 PLVELAEAGAHGFSDDGSPVWDAHIMRQALLYSKMTGRPVMNHCEDLSIVRGAPMNEGAV 202
Query: 192 SAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEV 251
+ LG+ G P+ E IARDI LAE H+CH+S V +R K +RVT EV
Sbjct: 203 ATRLGLSGWPAAGEEVMIARDIALAEETGGRLHICHVSTAGGVELIRAAKARGVRVTGEV 262
Query: 252 TPHHLLSCDEDIKEDNGMW------------------KMNPPLRGREDRNALIAGVLDGT 293
TPHHL D + W +++PPLR ED ALIAG+ DGT
Sbjct: 263 TPHHLTMTDRWVLGSMEPWDGKGPYDPSQLAPYDTRTRVSPPLRTSEDVAALIAGLRDGT 322
Query: 294 IDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENV 353
ID +ATDHAPHT +K +S G G E A + T V+T + L+ M+
Sbjct: 323 IDAVATDHAPHTHVDKECEYGFASPGFTGLELALPMVLT-LVQTMQIDIVELISRMTIGP 381
Query: 354 AKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
A I ++ L N A + + D + PE SKG+N+P +++ G +LT+ G
Sbjct: 382 AAIIDVLPISLGPNDPATLTIFDPAAIWKVTPEALASKGKNSPLMGQEMRGQVMLTMMEG 441
Query: 414 KIAY 417
+I Y
Sbjct: 442 QIVY 445
>gi|152966948|ref|YP_001362732.1| dihydroorotase, multifunctional complex type [Kineococcus
radiotolerans SRS30216]
gi|151361465|gb|ABS04468.1| dihydroorotase, multifunctional complex type [Kineococcus
radiotolerans SRS30216]
Length = 430
Score = 259 bits (663), Expect = 2e-67, Method: Composition-based stats.
Identities = 144/409 (35%), Positives = 222/409 (54%), Gaps = 5/409 (1%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
D+L++D +I + + +D G +D H H REPG ETV + +R+A
Sbjct: 18 DLLLRDGEIAAVGPGLSAEGATVLDASGLIALPGLVDLHTHLREPGREDAETVDSGTRSA 77
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI 137
ARGG+T+V M N PV D+ + + + + + P GA+T G +L+++ +
Sbjct: 78 ARGGYTSVFAMANTFPVADTAGVVEQVQRLGEEAGWVDVRPVGAVTVGLAGEQLAELGAM 137
Query: 138 ADK---VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAE 194
AD V F+DDG V A +M A+ + I H ++ L M+EG SA
Sbjct: 138 ADSRAGVRVFSDDGHCVSDAVLMRRALEYVKAFDGVIAQHAQEPRLTEDAQMNEGAVSAV 197
Query: 195 LGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPH 254
LG++G PS+ E IARD+LLA+ HVCH+S + SV VR K+ ++VT EVTPH
Sbjct: 198 LGLRGWPSVAEEAIIARDVLLADHVGSRLHVCHLSTRGSVEIVRWAKQRGVQVTAEVTPH 257
Query: 255 HLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIE 314
HLL DE ++ + ++K+NPPLR + D A+ G+ DGTID++ATDHAPH +E K
Sbjct: 258 HLLLTDELVRGYDPVYKVNPPLRTQADVEAVREGLADGTIDVVATDHAPHPVEAKDCEWS 317
Query: 315 KSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LEENSFADI 372
++ G+ G ETA + + V T + ++L MS A+I LP +G+ L S A++
Sbjct: 318 AAAMGMTGLETALSVVQHTMVDTGLVGWDVLADRMSSAPARIGRLPGHGRPLAVGSPANL 377
Query: 373 VVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKE 421
V++D T++P + GRN+P+ ++ G V T G+ +D E
Sbjct: 378 VLLDPAARWTVDPAAMATAGRNSPFRGMELPGRVVATFLRGRATVLDGE 426
>gi|68171217|ref|ZP_00544622.1| Dihydroorotase multifunctional complex type [Ehrlichia chaffeensis
str. Sapulpa]
gi|88658539|ref|YP_507193.1| dihydroorotase, multifunctional complex type [Ehrlichia chaffeensis
str. Arkansas]
gi|67999372|gb|EAM86016.1| Dihydroorotase multifunctional complex type [Ehrlichia chaffeensis
str. Sapulpa]
gi|88599996|gb|ABD45465.1| dihydroorotase, multifunctional complex type [Ehrlichia chaffeensis
str. Arkansas]
Length = 447
Score = 259 bits (663), Expect = 2e-67, Method: Composition-based stats.
Identities = 159/413 (38%), Positives = 233/413 (56%), Gaps = 14/413 (3%)
Query: 19 ILIKDDKI-----EKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
+L K DKI + + I T + ID + + G ID HVH+REPG KET+ T
Sbjct: 39 LLTKGDKIIDFGPDLFANGIPSTIDEVIDCNNNILLPGLIDIHVHFREPGQEHKETINTG 98
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP-YGAITKEEYGRELS 132
S++AA GG TTV+ PN P SV T K +++ +S I Y +ITK + LS
Sbjct: 99 SKSAAAGGITTVVCQPNTIPTISSVITA-KYIKMRALESAYVNIEFYASITKSD--NSLS 155
Query: 133 DMEDIAD-KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
DM + + FTDDG V +A M +A+ S L+ I H ED ++ G ++EG
Sbjct: 156 DMALLKEVGAVGFTDDGMPVMNALTMRQALSYSSMLDTVIAQHAEDLNISNNGCINEGII 215
Query: 192 SAELGIKGIPSICESTQIARDI-LLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
S ELG+KGIP I ES + RDI L+ N HYH+ H+S++ES+ +++ K ++VTCE
Sbjct: 216 SYELGLKGIPDISESIIVNRDIALMKNIKNVHYHILHVSSQESLHIIKQAKSQGLKVTCE 275
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
VTPHH + DI + KMNPPLR DR ++I G+ G ID IATDHAPH + K
Sbjct: 276 VTPHHFTLTERDIMTHGSLAKMNPPLRTENDRLSMIEGLKSGIIDCIATDHAPHDINAKE 335
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
++ ++FGIVG ET + + L L+ ++ A I +P G+++++ A
Sbjct: 336 LPLDTAAFGIVGLETMLP-ISLELYHNGTMPLIDLLATLTYKPADIIKVPRGRIKKDYVA 394
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKEEI 423
D++++DL+ E ++ +F SK +N+P+ N KV G + TI +GK Y K EI
Sbjct: 395 DLIILDLDHEWVVDISKFASKSKNSPFHNRKVKGKVLRTIVSGKTTY--KAEI 445
>gi|110598189|ref|ZP_01386466.1| dihydroorotase, multifunctional complex type [Chlorobium
ferrooxidans DSM 13031]
gi|110340203|gb|EAT58701.1| dihydroorotase, multifunctional complex type [Chlorobium
ferrooxidans DSM 13031]
Length = 444
Score = 259 bits (662), Expect = 2e-67, Method: Composition-based stats.
Identities = 150/408 (36%), Positives = 213/408 (52%), Gaps = 34/408 (8%)
Query: 37 DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPD 96
++ +D++ + + G D H H+REPG KET+ + S AAA GGFT V MPN PV D
Sbjct: 46 EDRIVDLRGQILAPGLFDMHCHFREPGQEYKETLESGSEAAAAGGFTGVALMPNTKPVID 105
Query: 97 S----------VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIAD-KVFAFT 145
S L LE++ GA+T E G L+ V A +
Sbjct: 106 SPLGVAYIRHHAANLAVDLEVV-----------GAMTVESRGEHLAPFGKFRSYGVTAIS 154
Query: 146 DDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICE 205
DDG +QS+ +M A S + I+ HCED SL +G M+EG SA+LG+KGIP I E
Sbjct: 155 DDGTAIQSSQIMRLAFEYASNFDLLIIQHCEDKSLTQGAVMNEGVFSAQLGLKGIPDISE 214
Query: 206 STQIARDILLAEAANCH----------YHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
+ + RD+LL E H YHV HIS ++ VR+ K++ + VTCEVTPHH
Sbjct: 215 AITLGRDLLLMEYLQKHKLHEPLRKPRYHVAHISTGAALDLVRKAKRDGLAVTCEVTPHH 274
Query: 256 LLSCDEDI--KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGI 313
CDE + ED G + M PPL RE+ A++ G+ DGTID IATDHAPH EK +
Sbjct: 275 FTLCDESLFQAEDKGNYLMKPPLGSRENLEAILQGLADGTIDAIATDHAPHASHEKECPL 334
Query: 314 EKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
++++FGI+G ET+ T+ V+ I ++ ++L+S N +I L A+
Sbjct: 335 DQAAFGIIGLETSVGLTLTELVEKRIITISRAIELLSVNPRRIMKLKPILFAPGEVANFT 394
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKE 421
I+ EKE PE SK NTP+ + + G G++ + + E
Sbjct: 395 FINPEKEWRCTPESIRSKSSNTPFLDRTMKGKASGIFHKGRLLFSEPE 442
>gi|73667255|ref|YP_303271.1| Dihydroorotase multifunctional complex type [Ehrlichia canis str.
Jake]
gi|72394396|gb|AAZ68673.1| Dihydroorotase multifunctional complex type [Ehrlichia canis str.
Jake]
Length = 447
Score = 259 bits (661), Expect = 3e-67, Method: Composition-based stats.
Identities = 153/407 (37%), Positives = 234/407 (57%), Gaps = 12/407 (2%)
Query: 19 ILIKDDKIEKISEN-----IDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
+L K DKI ++ I T + +D + + G ID HVH+REPG KET++T
Sbjct: 39 LLTKGDKIVDFGQDLFNNGIPSTIDEVVDCNNNILMPGLIDIHVHFREPGQEHKETIHTG 98
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP-YGAITKEEYGRELS 132
S++AA GG TTV+ PN P S+ T K +++ +S I Y +ITK + LS
Sbjct: 99 SKSAAAGGVTTVVCQPNTIPTISSIITA-KYIKMRALESAYVNIEFYASITKPD--NSLS 155
Query: 133 DMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
DM + + FTDDG V ++ M +A+ S L+ + H ED +L G ++EG
Sbjct: 156 DMALLKEAGAVGFTDDGMPVMNSLTMRQALSYSSMLDTVVAQHAEDLNLSNNGHINEGTV 215
Query: 192 SAELGIKGIPSICESTQIARDI-LLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
S ELG+KGIP I ES + RDI L+ N HYH+ H+S+++S+ +++ K ++VTCE
Sbjct: 216 SYELGLKGIPDISESIIVNRDIALMKNIKNVHYHILHVSSQDSLNIIKQAKNQGLKVTCE 275
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
VTPHHL ++D+ + K+NPPLR DR +++ G+ +G ID IATDHAPH + K
Sbjct: 276 VTPHHLTLTEQDVITHGTLAKINPPLRTENDRLSMVEGLKNGIIDCIATDHAPHEVNTKE 335
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
++ ++FGIVG ET + + SL L+ ++ A I +P G++++ A
Sbjct: 336 LPLDTAAFGIVGLETMLP-ISLELYHNGTISLIDLLATLTYKPANIIKVPRGRIKKGFVA 394
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
D++++DL E TI+ +F SK +N+P+ N KV G + TI +GK Y
Sbjct: 395 DLIILDLNHEWTIDILKFASKSKNSPFHNRKVKGKVLRTIVSGKTTY 441
>gi|88608169|ref|YP_506052.1| dihydroorotase, multifunctional complex type [Neorickettsia
sennetsu str. Miyayama]
gi|88600338|gb|ABD45806.1| dihydroorotase, multifunctional complex type [Neorickettsia
sennetsu str. Miyayama]
Length = 438
Score = 258 bits (658), Expect = 7e-67, Method: Composition-based stats.
Identities = 144/383 (37%), Positives = 214/383 (55%), Gaps = 4/383 (1%)
Query: 38 ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDS 97
+ ++ + G ID HVH R+PG + E +++ +++AA GG TTV+ PN +P D+
Sbjct: 58 DEVVNCDGHILMPGIIDIHVHLRDPGQLQNEDIHSGTKSAAAGGVTTVVCQPNTDPPIDT 117
Query: 98 VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANV 156
VETL + K + + Y +IT G +L+DM + FTDDG V ++
Sbjct: 118 VETLAYIRDKAKRVGFVNVLCYASITGR--GGDLTDMFALHKAGAVGFTDDGLPVMNSLF 175
Query: 157 MYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLA 216
M +A + + L + H ED L GG ++EG S +L + GI + ES +ARD+LL
Sbjct: 176 MRQAFMNAALLKVPVAQHAEDLDLSNGGCINEGAISHKLNVPGISHLAESVMVARDVLLL 235
Query: 217 EAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPL 276
E HYHV H+S K++V VR K +RVTCEVTPHHLL +E + N KMNPPL
Sbjct: 236 EQLGAHYHVLHVSTKKTVEIVRAAKDKGMRVTCEVTPHHLLLTEEAVDGYNTAAKMNPPL 295
Query: 277 RGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVK 336
R EDR +I + DGTID IA+DHAPH K +++++FG+VG ET L +
Sbjct: 296 RTEEDRLCMIEALKDGTIDAIASDHAPHNEVYKELPLKEAAFGVVGLETILP-LSLELYH 354
Query: 337 TDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTP 396
+ L L+ ++ N AKI G+++ + AD+V++DL E+ I +F+SK +N+P
Sbjct: 355 SGALELHSLLAKLTCNPAKIIGSEAGRIKVGAPADLVLLDLNSEVRIETRQFVSKSKNSP 414
Query: 397 YANEKVNGIPVLTISNGKIAYID 419
+ K G + TI G Y+D
Sbjct: 415 FGGRKTRGKVLRTIVGGDTVYMD 437
>gi|83816824|ref|YP_446303.1| Amidohydrolase family, putative [Salinibacter ruber DSM 13855]
gi|83758218|gb|ABC46331.1| Amidohydrolase family, putative [Salinibacter ruber DSM 13855]
Length = 430
Score = 257 bits (657), Expect = 8e-67, Method: Composition-based stats.
Identities = 155/407 (38%), Positives = 221/407 (54%), Gaps = 11/407 (2%)
Query: 15 KKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
+ D+LI+D I I ++DV D+ D F++ G++D HVH REPG+ KETV T
Sbjct: 21 QDADLLIRDGTIATIGTDLDVGDDVPAYDASGLFISPGWMDMHVHLREPGYEHKETVATG 80
Query: 74 SRAAARGGFTTVMTMPNLNP---VPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRE 130
SRAA GGFT V MPN +P D VE + ++ E D+ + P ++KE G E
Sbjct: 81 SRAALAGGFTDVACMPNTDPPLHTRDVVEFVRERAE----DTPVGVHPIACVSKERAGDE 136
Query: 131 LSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEG 189
+++M D+ A AF+DDG V +A +M A+ S L++ I+ H E+ +L G MHEG
Sbjct: 137 IAEMADLEAGGAVAFSDDGAPVPTAGLMRRALEYSSMLDRPIINHMEEETLNPSGQMHEG 196
Query: 190 KRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTC 249
+ SA LG+ GIP+ E IARDI LA HV HIS V VR K + + VT
Sbjct: 197 EVSARLGLDGIPAASEDVMIARDIELAARTGGALHVAHISTARGVELVRRAKAHGVPVTA 256
Query: 250 EVTPHHLLSCDEDIKED--NGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
EV HHL D ++ + KM+PPLR D AL G+ DGTID I TDHAPH
Sbjct: 257 EVCTHHLTLTDAAVEASQFDTNTKMHPPLRSPADVAALKEGLADGTIDAICTDHAPHASY 316
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEEN 367
EK + FGI+G ETA+ + + ++ + S+E V+ ++ +I +L L E
Sbjct: 317 EKQVEFAHAPFGILGLETAWGLIGRELIEPGVLSVEEAVRTLTVAPRRILHLDEPGLTEG 376
Query: 368 SFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
+ A + V D E T ++ SK NTP+ + ++ G P S+G+
Sbjct: 377 TPARLTVFDASTEWTFTKDDIRSKSENTPFTDAEMVGRPRAVYSDGQ 423
>gi|116511900|ref|YP_809116.1| Dihydroorotase [Lactococcus lactis subsp. cremoris SK11]
gi|116107554|gb|ABJ72694.1| Dihydroorotase [Lactococcus lactis subsp. cremoris SK11]
Length = 423
Score = 256 bits (654), Expect = 2e-66, Method: Composition-based stats.
Identities = 154/421 (36%), Positives = 243/421 (57%), Gaps = 7/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + +D+LI+++KI KI N+ + ID + + G ID HVH
Sbjct: 3 LLIKNGRLIDPKSNRDEILDVLIEENKIAKIGTNLSEENTEIIDARGLVIAPGLIDVHVH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSV-IRAI 117
+REPG + KET+++ +++AA GGFTTV+ M N P+ + + L + L I K +++ I+A+
Sbjct: 63 FREPGQTHKETIHSGAKSAAAGGFTTVVMMANTKPILSTPKVLTETLAIAKKEAIKIKAV 122
Query: 118 PYGAITKEEYGRELSDM-EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
+IT++ G L+D E I F+DDG + A V+ +A+ + + H E
Sbjct: 123 --ASITQDFDGENLTDFAELIKAGAIGFSDDGIPLTDAGVLRKALQKAKLTDSLLSIHEE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D +LI +++G+ + + G G P++ E + +ARD ++A H+ H+SA ESV
Sbjct: 181 DPNLIGTLGVNDGEVAHKCGFTGAPTVSEYSMMARDAMIAYETGARLHLQHLSAGESVEV 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
VR K ++T EVTP H ++ I E K+NPPLR D + +IAG+ DGTID+
Sbjct: 241 VRFAKNLGAKITAEVTPQHFSITEQMIFEQGTNAKLNPPLRRDADISKIIAGLKDGTIDV 300
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
IATDHAPHT EEK I+K+ G++G ET+ T V +L L+ M+ N AK+
Sbjct: 301 IATDHAPHTHEEKNVSIDKAPSGMIGLETSLQLGLTNLVAKGHLTLLELLTKMTLNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
++ G L E AD+V+ D EK + E F SK N+P+ ++KV G TI +G I
Sbjct: 361 YDFDAGYLAEAGPADLVIFDAEKTYQVG-ETFDSKATNSPFIHQKVQGQVKYTICDGNIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|94984609|ref|YP_603973.1| dihydroorotase, multifunctional complex type [Deinococcus
geothermalis DSM 11300]
gi|94554890|gb|ABF44804.1| dihydroorotase, multifunctional complex type [Deinococcus
geothermalis DSM 11300]
Length = 417
Score = 255 bits (652), Expect = 3e-66, Method: Composition-based stats.
Identities = 141/380 (37%), Positives = 220/380 (57%), Gaps = 3/380 (0%)
Query: 39 NTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSV 98
+ +D + V I+ H H REPG ++KE + + AAA GG+ TV++MPN +PV D
Sbjct: 37 DVLDGQGGTVAPALIELHAHLREPGQTEKEDLASGLAAAAAGGYGTVVSMPNTSPVVDDP 96
Query: 99 ETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADKVFA-FTDDGRGVQSANVM 157
+ +E + + R P A+T+ + G +L+++ + D A FTDDGR ++A V+
Sbjct: 97 AIVRSLIEKAEGVGLARLKPAAALTRGQKGEQLAELAFLRDAGAAMFTDDGRTNENARVL 156
Query: 158 YEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAE 217
+ L + H ED +L G M+EG S ELG+ G P E+ ++ARD+ L
Sbjct: 157 RLGLEYARSLGMVVSVHAEDAALRADGVMNEGLVSEELGLPGNPGAAEAARVARDLELVA 216
Query: 218 AANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLR 277
H+ H+S ++ VR+ K+ + VTCEV PHHL DE ++ + ++K+ PPLR
Sbjct: 217 LTGARLHLQHLSTARALELVRDAKRRGLPVTCEVCPHHLTLTDEALRSFDAIYKVAPPLR 276
Query: 278 GREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKT 337
+ D AL+ G+LDGT+D +ATDHAPHT EK R + ++ FGI E AF ++T+F
Sbjct: 277 TQADAAALLEGLLDGTVDCLATDHAPHTRAEKERDLLQAPFGIPSLELAFPLMWTRF--G 334
Query: 338 DIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPY 397
+ LE L++LM+ A++ P L + AD+VV+DL E +NP F SK + +P+
Sbjct: 335 EQLGLEKLLELMTAAPARVLGWPEPTLNAGAPADLVVLDLTTEREVNPATFRSKAKFSPW 394
Query: 398 ANEKVNGIPVLTISNGKIAY 417
A E++ G P+LT+ GK+A+
Sbjct: 395 AGEQLRGWPLLTVVGGKLAF 414
>gi|25028287|ref|NP_738341.1| dihydroorotase [Corynebacterium efficiens YS-314]
gi|23493571|dbj|BAC18541.1| putative dihydroorotase [Corynebacterium efficiens YS-314]
Length = 450
Score = 255 bits (652), Expect = 3e-66, Method: Composition-based stats.
Identities = 145/391 (37%), Positives = 216/391 (55%), Gaps = 5/391 (1%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVY 71
G+ + ++LI+D I+ + ++TID + GF+D HVH REPG ET+
Sbjct: 29 GEGEPTNVLIRDGVIDSLDAPTSGEYDHTIDGGGGVLLPGFVDMHVHLREPGREDTETIA 88
Query: 72 TASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGREL 131
T S AAA+GGFT V TM N PV D +N + P G+ITK GREL
Sbjct: 89 TGSAAAAKGGFTAVFTMANTTPVMDQPLIAEGVWFKGQNVGLCDVHPVGSITKGLEGREL 148
Query: 132 SDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
++ +A +V F+DDG+ V VM A+ ++ I HCED+ + G + HE
Sbjct: 149 TEFGMMARSEARVRMFSDDGKCVDDPQVMRRALEYAKGMDVLIAQHCEDHRMTEGASAHE 208
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G+ +A LG++G P + E + + RD +LA H+CH S + ++ +R K I +T
Sbjct: 209 GENAARLGLRGWPRVAEESIVVRDAILARDYGNRVHICHASTEGTIELLRWAKGQGIPIT 268
Query: 249 CEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEE 308
EVTPHHL+ DE +K +G+ ++NPPLR D AL +LDGTID++ATDHAPH E+
Sbjct: 269 AEVTPHHLILTDERLKTYDGVNRVNPPLREERDTLALREALLDGTIDVVATDHAPHGSED 328
Query: 309 KIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LEE 366
K E + G++G ET+ + + FV + + + K+MSE A+I LP +G+ +
Sbjct: 329 KCCEFENAKPGMLGLETSLSIIADTFVASGLADWRFVAKVMSERPAEITRLPGHGRPIAV 388
Query: 367 NSFADIVVIDLEKEITINPEEFLSKGRNTPY 397
A++ ++D + T EEF SK NTPY
Sbjct: 389 GEPANLTIVDPGRTWTARGEEFASKASNTPY 419
>gi|125624314|ref|YP_001032797.1| putative dihydroorotase [Lactococcus lactis subsp. cremoris MG1363]
gi|124493122|emb|CAL98086.1| putative dihydroorotase [Lactococcus lactis subsp. cremoris MG1363]
Length = 423
Score = 255 bits (652), Expect = 4e-66, Method: Composition-based stats.
Identities = 159/422 (37%), Positives = 245/422 (58%), Gaps = 9/422 (2%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + +DILI+++KI KI N+ + ID + G ID HVH
Sbjct: 3 LLIKNGRLIDPKSNRDEILDILIEENKIAKIGTNLSEENTEIIDASGLVIAPGLIDVHVH 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSV-IRAI 117
+REPG + KET+++ +++AA GGFTTV+ M N P+ + + L + L I K +++ I+A+
Sbjct: 63 FREPGQTHKETIHSGAKSAAAGGFTTVVMMANTKPILSTPKVLTETLAIAKKEAIKIKAV 122
Query: 118 PYGAITKEEYGRELSDM-EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVA-HC 175
+IT++ G L+D E I F+DDG + A V+ EA L SKL ++++ H
Sbjct: 123 --ASITQDFDGENLTDFAELIKAGAIGFSDDGIPLTDAGVLREA-LQKSKLTDSLLSIHE 179
Query: 176 EDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVR 235
ED +LI +++G+ + + G G P++ E + +ARD ++A H+ H+SA ESV
Sbjct: 180 EDPNLIGTLGVNDGEVAHKCGFTGAPTVSEYSMMARDTMIAYETGARLHLQHLSAGESVE 239
Query: 236 AVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTID 295
VR K ++T EVTP H ++ I E K+NPPLR D + +IAG+ DGTID
Sbjct: 240 VVRFAKNLGAKITAEVTPQHFSITEQMIFEQGTNAKLNPPLRRDADISKIIAGLKDGTID 299
Query: 296 IIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
+IATDHAPHT EEK I+K+ G++G ET+ T V +L L+ M+ N AK
Sbjct: 300 VIATDHAPHTHEEKNVSIDKAPSGMIGLETSLQLGLTNLVAKGHLTLLELLTKMTLNPAK 359
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
+++ G L E AD+V+ D E + E F SK N+P+ +KV G TI +G I
Sbjct: 360 LYDFDAGYLAEAGPADLVIFDAENTYQVG-ETFDSKATNSPFIYQKVQGQIKYTICDGNI 418
Query: 416 AY 417
Y
Sbjct: 419 VY 420
>gi|50954775|ref|YP_062063.1| dihydroorotase [Leifsonia xyli subsp. xyli str. CTCB07]
gi|71648817|sp|Q6AF87|PYRC_LEIXX Dihydroorotase (DHOase)
gi|50951257|gb|AAT88958.1| dihydroorotase [Leifsonia xyli subsp. xyli str. CTCB07]
Length = 438
Score = 253 bits (647), Expect = 1e-65, Method: Composition-based stats.
Identities = 143/409 (34%), Positives = 217/409 (53%), Gaps = 5/409 (1%)
Query: 16 KVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASR 75
+ D+L+ +I++ + +D G +D H H REPG+ + ETV T +R
Sbjct: 18 RTDLLLAGGRIQETGVRLSAAGATVVDADGLLALPGLVDLHTHLREPGYEQSETVLTGTR 77
Query: 76 AAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDME 135
AAA GGFT V M N +PV D+ + + L + + P GA+T G L+++
Sbjct: 78 AAAAGGFTEVFAMANTSPVADTAGVVEQVLSLGEAAGYATVRPIGAVTVGLEGERLAELG 137
Query: 136 DIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRS 192
+AD +V F+DDG+ V +M A+ + I H ++ + G M+EG S
Sbjct: 138 AMADSRARVRVFSDDGKCVSDPLLMRRALEYVKAFDGVIAQHAQEPRITAGAQMNEGALS 197
Query: 193 AELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVT 252
ELG+ G P++ E + IARD+LLAE HVCH+S SV +R K I VT EVT
Sbjct: 198 GELGLAGWPAVAEESIIARDVLLAEHVGSRLHVCHVSTAGSVDVIRWAKARGIDVTAEVT 257
Query: 253 PHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRG 312
PHHLL +E + + +K+NPPLR ED AL AG+ DGTIDI+ATDHAPH +E K
Sbjct: 258 PHHLLLTEELVSGYDARYKVNPPLRRSEDVEALRAGLADGTIDIVATDHAPHPVEAKDCE 317
Query: 313 IEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LEENSFA 370
+ ++FG+VG E+A + + + V T + + +++S A+I L +G +E + A
Sbjct: 318 WDAAAFGMVGLESALSVVQSSVVDTGMLGWADIARVLSATPARIGRLAGHGTPVEAGAPA 377
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
++ + D + E KG N+PY + ++G V T G +D
Sbjct: 378 ELFLYDPAAAREFSTGELAGKGVNSPYLSMTLSGRVVATFHRGYATVLD 426
>gi|153955968|ref|YP_001396733.1| PyrC [Clostridium kluyveri DSM 555]
gi|146348826|gb|EDK35362.1| PyrC [Clostridium kluyveri DSM 555]
Length = 393
Score = 253 bits (647), Expect = 1e-65, Method: Composition-based stats.
Identities = 153/417 (36%), Positives = 234/417 (56%), Gaps = 28/417 (6%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+K +I+ + DI I D I KI N++ ID + V F+D HVH+R
Sbjct: 3 LLIKKARIVDYYQNFTGDIYINDGIINKIGVNLN-EKCLKIDGEGLVVMPSFVDLHVHFR 61
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPGF++KE + + SRAAA+GG+T V M N +PV S++T+N L K ++
Sbjct: 62 EPGFTRKEDIESGSRAAAKGGYTMVNLMANTDPVCSSMDTVNYVLNRAKQVGILDVHQCV 121
Query: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
+IT G++ S ++ + D+V ++DG+ V ++VM EAM+ K + ++ H ED+SL
Sbjct: 122 SITDNFEGKDTSHLDKLDDRVKIISEDGKDVTDSSVMLEAMVKAKKSRRIVMCHSEDHSL 181
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
+ + ++ + E+ R+I L+E C H+ H+S KES+ + EG
Sbjct: 182 ------------SNIDMR----LAENIMTWRNITLSEFTGCAVHIAHVSTKESMEYIMEG 225
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K +TCEV PHH++ + D +++NPP+R +EDR+ LI + DG +D I+TD
Sbjct: 226 KIKGANITCEVAPHHIVLYEND-------YRVNPPIRTKEDRDFLIKSIKDGWVDTISTD 278
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPHT E+K++G GI G ETAF+ YT VK +L L LMS+N + I +
Sbjct: 279 HAPHTSEDKMQGAP----GISGIETAFSLCYTNLVKGGHITLNKLSGLMSKNPSDILGIK 334
Query: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G++ D+V++DL KE I EEFLSKG+NTP+ V G V TI GK+ +
Sbjct: 335 KGRITPGYEGDLVLLDLNKEYKIQREEFLSKGKNTPFEGYMVFGDIVKTIKAGKVVF 391
>gi|29833406|ref|NP_828040.1| dihydroorotase [Streptomyces avermitilis MA-4680]
gi|29610529|dbj|BAC74575.1| putative dihydroorotase [Streptomyces avermitilis MA-4680]
Length = 428
Score = 253 bits (645), Expect = 2e-65, Method: Composition-based stats.
Identities = 148/424 (34%), Positives = 219/424 (51%), Gaps = 8/424 (1%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L++ K+L + D+LI D I ++ + +D + + G +D H H R
Sbjct: 4 ILIRGAKVLGG---EPQDVLIDGDTIAEVGTGLSAEGAEVVDAAGKVLLPGLVDLHTHLR 60
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG ETV T +RAAA GG+T V M N PV D+ + + + + P G
Sbjct: 61 EPGREDSETVLTGTRAAASGGYTAVFAMANTFPVADTAGVVEQVYRLGQEHGYCDVQPIG 120
Query: 121 AITKEEYGRELSD---MEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
A+T G++L++ M + A V F+DDG+ V A +M A+ + H ++
Sbjct: 121 AVTVGLEGKKLAELGAMHESAAGVTVFSDDGKCVDDAVIMRRALEYVKAFGGVVAQHAQE 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L G M+EG SAELG+ G P++ E + IARD+LLAE H+CH+S SV V
Sbjct: 181 PRLTEGAQMNEGVVSAELGLGGWPAVAEESIIARDVLLAEHVGSRVHICHLSTAGSVEIV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K I VT EVTPHHLL DE ++ N ++K+NPPLR D AL + DGTIDI+
Sbjct: 241 RWAKSRGIDVTAEVTPHHLLLTDELVRSYNPVYKVNPPLRTERDVMALREALADGTIDIV 300
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH E+K ++ G+VG ETA + + V+T + + MS A+I
Sbjct: 301 ATDHAPHPHEDKDCEWAAAAMGMVGLETALSVVQQTMVETGLLDWAGVADRMSVKPARIG 360
Query: 358 NLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
+G+ + A++ ++D ++P F S+ RNTPY ++ G T GK
Sbjct: 361 RATGHGRPVSAGEPANLTLVDTAYRGAVDPAGFASRSRNTPYEGRELPGRVTHTWLRGKA 420
Query: 416 AYID 419
+D
Sbjct: 421 TLVD 424
>gi|21219987|ref|NP_625766.1| dihydroorotase [Streptomyces coelicolor A3(2)]
gi|22001888|sp|Q9KXR3|PYRC_STRCO Dihydroorotase (DHOase)
gi|8249945|emb|CAB93366.1| dihydroorotase [Streptomyces coelicolor A3(2)]
Length = 428
Score = 252 bits (644), Expect = 3e-65, Method: Composition-based stats.
Identities = 149/423 (35%), Positives = 217/423 (51%), Gaps = 8/423 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
L++ K+L + D+LI +E + N+ ++ + + G +D H H RE
Sbjct: 5 LIRGAKVLGG---EPQDVLIDGTVVEAVGTNLSAEGAEVVEADGKVLLPGLVDLHTHLRE 61
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG ETV T +RAAA GG+T V M N PV D+ + + + + P GA
Sbjct: 62 PGREDSETVLTGTRAAASGGYTNVFAMANTFPVADTAGVVEQVWRLGQESGYCDVQPIGA 121
Query: 122 ITKEEYGRELSD---MEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+T G +L++ M + A V F+DDG+ V A +M A+ N + H ++
Sbjct: 122 VTVGLEGAKLAELGAMHESAAGVTVFSDDGKCVHDAVIMRRALEYVKAFNGVVAQHAQEP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
L G M+EG SAELG+ G P++ E + IARD+LLAE H+CH+S SV VR
Sbjct: 182 RLTEGAQMNEGVVSAELGLGGWPAVAEESVIARDVLLAEHVGSRVHICHLSTAGSVEIVR 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
K I VT EVTPHHLL DE ++ N ++K+NPPLR D AL + DGTIDI+A
Sbjct: 242 WAKSRGIDVTAEVTPHHLLLTDELVRSYNPVYKVNPPLRTERDVMALREALADGTIDIVA 301
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH E+K ++ G+VG ETA + + V T + + MS AKI
Sbjct: 302 TDHAPHPHEDKDCEWAAAAMGMVGLETALSVVQETMVDTGLLDWAGVADRMSFKPAKIGQ 361
Query: 359 LP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+G+ + A++ ++D ++P F S+ RNTPY ++ G T GK
Sbjct: 362 ATGHGRPVSAGEPANLTLVDAAYRGQVDPAGFASRSRNTPYEGRELPGRVTHTWLRGKAT 421
Query: 417 YID 419
+D
Sbjct: 422 LVD 424
>gi|119962159|ref|YP_948008.1| dihydroorotase, multifunctional complex type [Arthrobacter
aurescens TC1]
gi|119949018|gb|ABM07929.1| dihydroorotase, multifunctional complex type [Arthrobacter
aurescens TC1]
Length = 441
Score = 251 bits (641), Expect = 6e-65, Method: Composition-based stats.
Identities = 143/409 (34%), Positives = 218/409 (53%), Gaps = 5/409 (1%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
D+LI+D IE +++ D ID + G +D H H REPG ETV T +RAA
Sbjct: 20 DLLIRDGVIEARGKDLSADDATVIDAQGLVALPGMVDVHTHLREPGREDAETVETGTRAA 79
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI 137
A GGFT V M N NPV D+ + + + + + P GA+T G +L+++ +
Sbjct: 80 ALGGFTAVHAMANSNPVADTAGVVEQVHSLGRASGWVDVRPVGAVTVGLAGEQLAELGAM 139
Query: 138 AD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAE 194
AD +V F+DDG V +M A+ + + H ++ L G M+EG SA
Sbjct: 140 ADSRAQVRMFSDDGICVHDPVLMRRALEYVKAFDGVVAQHAQEPRLTAGAQMNEGTVSAV 199
Query: 195 LGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPH 254
LG+ G P++ E + IARD+LLA+ HVCH+S SV VR K I VT EVTPH
Sbjct: 200 LGLTGWPAVAEESIIARDVLLAQHVGSRLHVCHVSTAGSVEIVRWAKARGINVTAEVTPH 259
Query: 255 HLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIE 314
HLL DE ++ + ++K+NPPLR D AL G+ DGTID++ TDHAPH E K
Sbjct: 260 HLLLTDELVRSYDPVYKVNPPLRTDADVQALREGLADGTIDVVGTDHAPHPSEHKECEWA 319
Query: 315 KSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LEENSFADI 372
+++ G+ G ETA + + ++T + + ++ S A I + G+ LE A++
Sbjct: 320 QAAMGMTGLETALSVVQETMIETGLMTWADFARVTSFTPAVIGRVADQGRPLEVGEPANV 379
Query: 373 VVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKE 421
+++D T++P + + GRN+P+ +++ G V T G +D +
Sbjct: 380 ILVDPAARWTVDPHKMATMGRNSPFKGKELPGSVVATFFKGHPTVLDGQ 428
>gi|51243957|ref|YP_063841.1| dihydroorotase [Desulfotalea psychrophila LSv54]
gi|50874994|emb|CAG34834.1| probable dihydroorotase [Desulfotalea psychrophila LSv54]
Length = 421
Score = 250 bits (638), Expect = 1e-64, Method: Composition-based stats.
Identities = 151/420 (35%), Positives = 230/420 (54%), Gaps = 6/420 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
++LK +++ +N + + DI ++D +I E + D D+ ++V G ID HVH
Sbjct: 3 IILKGGRVIDPRNRRDEDADIWMEDGQIIAPQETVP-EDAKIYDLAGKWVVPGLIDMHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
R+PG KE++ T + AAA GGFT V MPN +PV D+ LE + R P
Sbjct: 62 LRDPGEEYKESIVTGTDAAAAGGFTAVACMPNTDPVNDTGSVTRYILEK-SEGAAARVYP 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
GA+++ G L++ D+ A TDDG V S+ +M AM + +++H E+
Sbjct: 121 VGALSEGLKGESLAEYADMKHAGAVALTDDGNPVVSSQLMRRAMEYAKSHDMLVISHSEE 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
+L + G M+EG + LG+KGIP++ ES + R+I LA H+ H+S ES+ A+
Sbjct: 181 PTLSKRGCMNEGLVATRLGLKGIPAVAESIMVQREIALAGLTGARLHIAHVSCIESLAAI 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R+ KK + VT E PH+ D+ + + KMNPPLR E R A+ + DGT+D+I
Sbjct: 241 RDAKKRGLPVTAETAPHYFSLTDDAVIGYDTHAKMNPPLRTEEHRQAIRQALADGTLDVI 300
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH++ EK E ++ GIVG ET+ L V+ + + LV+LMS A+I
Sbjct: 301 ATDHAPHSIVEKEVTFEYAANGIVGLETSLG-LSLALVRDGVLTPSRLVELMSSVPAQIL 359
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
++ G+L + AD+ VID E E T E S+G N+P+ K+ G LT G+ +Y
Sbjct: 360 SVAGGELGVGAIADVTVIDPELEHTFLIAEGRSRGANSPFDGWKLKGAATLTFVAGEESY 419
>gi|72161459|ref|YP_289116.1| dihydroorotase [Thermobifida fusca YX]
gi|71915191|gb|AAZ55093.1| dihydroorotase multifunctional complex type [Thermobifida fusca YX]
Length = 431
Score = 250 bits (638), Expect = 1e-64, Method: Composition-based stats.
Identities = 152/428 (35%), Positives = 215/428 (50%), Gaps = 18/428 (4%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
L++N +IL + D+L+ +I+ I ++ +D G +D H H RE
Sbjct: 8 LIRNARILGG---EPTDLLLAHGRIDAIGPDLPADGAEVVDAAGAIALPGLVDLHTHLRE 64
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG ETV T SRAAA GG+T V M N +PV D+ + + + ++ P GA
Sbjct: 65 PGREDAETVATGSRAAAMGGYTAVFAMANTDPVADTAGVVEQVWRLGRDAGYCDVHPVGA 124
Query: 122 IT---KEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+T K E EL M D KV F+DDG V A +M A+ + I H ++
Sbjct: 125 VTVGLKGERLAELGAMADSPAKVRVFSDDGMCVSDAQLMRRALEYVKAFDGVIAQHAQEP 184
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
L G M+EG S LG+ G P++ E IARD LLAE HVCH+S K SV+ +R
Sbjct: 185 RLTEGAQMNEGVVSDRLGLAGWPAVAEEAIIARDCLLAEHVGSRLHVCHVSTKGSVQIIR 244
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
K VT EVTPHHLL DE + + ++K+NPPLR ED AL G+ DGTIDI+A
Sbjct: 245 WAKSRGCDVTAEVTPHHLLLTDELAESYDPVYKVNPPLRTAEDVEALREGLADGTIDIVA 304
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH E K +++ G++G ETA + + V T + + + MS A+I
Sbjct: 305 TDHAPHPSEAKETEWNQAAMGMIGLETALSVVQHTMVDTGLLDWAGVAQRMSATPARI-- 362
Query: 359 LPYGKLEENSF-------ADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTIS 411
G+L + A++ + D I+P +SK RNTP+A + G + T
Sbjct: 363 ---GRLTDQGRPIAVGEPANLTLYDPTATRVIDPATMVSKSRNTPFAGMTLPGRVLATFL 419
Query: 412 NGKIAYID 419
G +D
Sbjct: 420 RGVPTVLD 427
>gi|19552823|ref|NP_600825.1| dihydroorotase [Corynebacterium glutamicum ATCC 13032]
gi|62390494|ref|YP_225896.1| dihydroorotase [Corynebacterium glutamicum ATCC 13032]
gi|28201865|sp|Q8NQ39|PYRC_CORGL Dihydroorotase (DHOase)
gi|21324380|dbj|BAB99004.1| Dihydroorotase [Corynebacterium glutamicum ATCC 13032]
gi|41325831|emb|CAF21620.1| PUTATIVE DIHYDROOROTASE [Corynebacterium glutamicum ATCC 13032]
Length = 447
Score = 249 bits (637), Expect = 2e-64, Method: Composition-based stats.
Identities = 150/424 (35%), Positives = 226/424 (53%), Gaps = 9/424 (2%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+ N +L G+ + ++ +KD I I + + TID + GF+D HVH R
Sbjct: 22 LLISN--VLVYGEGEPTNVFVKDGVIAAIGGTHEA--DRTIDGNGGVLLPGFVDMHVHLR 77
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG ET+ T S AAA+GGFT V TM N PV D +N + P G
Sbjct: 78 EPGREDTETIATGSAAAAKGGFTAVFTMANTTPVMDQPVIAESVWFKGQNIGLCDVHPVG 137
Query: 121 AITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
+ITK G+EL++ +A KV F+DDG+ V VM A+ ++ I H ED
Sbjct: 138 SITKGLEGKELTEFGMMARSEAKVRMFSDDGKCVDDPQVMRRALEYAKGMDVLIAQHAED 197
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
+ L G + HEG+ +A LG++G P + E + + RD ++A H+CH S + +V +
Sbjct: 198 HRLTEGASAHEGENAARLGLRGWPRVAEESIVVRDAIMARDYGNRVHICHASTEGTVELL 257
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K I +T EVTPHHL DE ++ + + K+NPPLR D AL +LDGTID++
Sbjct: 258 RWAKSQGIPITAEVTPHHLTLTDERLETYDAVNKVNPPLRESRDAEALKKALLDGTIDVV 317
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH E+K E + G++G ET+ + + FV T + + ++MSE A+I
Sbjct: 318 ATDHAPHGSEDKCCEFENAKPGMLGLETSLSIIVDTFVATGLADWRFVARVMSERPAEIT 377
Query: 358 NLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
LP G+ + E A++ ++D K T + +F SK NTP+ ++ + T+ GK+
Sbjct: 378 RLPGQGRPIAEGEPANLAIVDPGKTWTASGADFASKAENTPFEGQEFSAKVTHTVLRGKV 437
Query: 416 AYID 419
D
Sbjct: 438 TCAD 441
>gi|150015888|ref|YP_001308142.1| dihydroorotase, multifunctional complex type [Clostridium
beijerinckii NCIMB 8052]
gi|149902353|gb|ABR33186.1| dihydroorotase, multifunctional complex type [Clostridium
beijerinckii NCIMB 8052]
Length = 411
Score = 249 bits (637), Expect = 2e-64, Method: Composition-based stats.
Identities = 160/423 (37%), Positives = 240/423 (56%), Gaps = 35/423 (8%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN +I+ + DI IKD IE+I + I D TI+ + + + FID H H+R
Sbjct: 3 LLIKNARIVDVTQDFIGDIYIKDGIIEEIGQKIFKIDVETIECEGKILMPSFIDTHAHFR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDS----VIRA 116
+PG + KE + T SRAA +GG+T V M N NP+ S K LE ++N S +I
Sbjct: 63 DPGLTWKEDIETGSRAALKGGYTGVCLMANTNPICSS----KKVLEYVRNKSKEINLIDI 118
Query: 117 IPYGAITKEEYGRELSDMEDI-ADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAH 174
++TK+ G L+ +E++ DK + A +DDG G+ ++N M EAM + K N I++H
Sbjct: 119 HQCLSVTKDFDGVTLTHLEELLGDKEIKAISDDGVGISNSNTMLEAMEVAKKNNWVIMSH 178
Query: 175 CEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESV 234
E S E K I E+ RD+ LA+ + H+CH+S KE++
Sbjct: 179 AE---------------SPEFS-KVDMRIAENMMTIRDVELAKLSKARLHMCHVSTKEAI 222
Query: 235 RAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTI 294
+ + +GK + +T EVTPHH+ + D +++NPP+R +ED A+I + G +
Sbjct: 223 KCIIDGKVSGANITLEVTPHHI-----GLTRDINDYRVNPPIREKEDVEAIINAIKLGMV 277
Query: 295 DIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVA 354
D I TDHAPHT +EK++G S G+VG ETAF+ YTK VK + SL L +LMS N A
Sbjct: 278 DTIGTDHAPHTADEKMKG----SPGMVGIETAFSICYTKLVKENNVSLNKLSELMSYNPA 333
Query: 355 KIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
K+ + GK+ D+V++D+ K + +NPEEF SKGRNTP+ + G ++TI G+
Sbjct: 334 KLLGMNKGKISIGVEGDLVLVDINKCLKVNPEEFASKGRNTPFTGMEFYGEILMTIKGGE 393
Query: 415 IAY 417
I Y
Sbjct: 394 IKY 396
>gi|145295733|ref|YP_001138554.1| hypothetical protein cgR_1660 [Corynebacterium glutamicum R]
gi|140845653|dbj|BAF54652.1| hypothetical protein [Corynebacterium glutamicum R]
Length = 447
Score = 249 bits (637), Expect = 2e-64, Method: Composition-based stats.
Identities = 151/424 (35%), Positives = 226/424 (53%), Gaps = 9/424 (2%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+ N +L G+ + ++L+KD I I + + TID + GF+D HVH R
Sbjct: 22 LLISN--VLVYGEGEPTNVLVKDGVIAAIGGTHEA--DRTIDGNGGVLLPGFVDMHVHLR 77
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG ET+ T S AAA+GGFT V TM N PV D +N + P G
Sbjct: 78 EPGREDTETIATGSAAAAKGGFTAVFTMANTFPVMDQPVIAESVWFKSQNIGLCDVHPVG 137
Query: 121 AITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
+ITK G+EL++ +A KV F+DDG+ V VM A+ ++ I H ED
Sbjct: 138 SITKGLEGKELTEFGMMARSEAKVRMFSDDGKCVDDPQVMRRALEYAKGMDVLIAQHAED 197
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
+ L G + HEG+ +A LG++G P + E + + RD ++A H+CH S + +V +
Sbjct: 198 HRLTEGASAHEGENAARLGLRGWPRVAEESIVVRDAIMARDYGNRVHICHASTEGTVELL 257
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K I +T EVTPHHL DE ++ + + K+NPPLR D AL +LDGTID++
Sbjct: 258 RWAKSQGIPITAEVTPHHLTLTDERLETYDAVNKVNPPLRESRDAEALKKALLDGTIDVV 317
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH E+K E + G++G ET+ + + FV T + + ++MSE A+I
Sbjct: 318 ATDHAPHGSEDKCCEFENAKPGMLGLETSLSIIVDTFVATGLADWRFVARVMSERPAEIT 377
Query: 358 NLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
LP G+ + E A++ ++D K T +F SK NTP+ ++ + T+ GK+
Sbjct: 378 RLPGQGRPIAEGEPANLAIVDPGKTWTACGADFASKAENTPFEGQEFSAKVTHTVLRGKV 437
Query: 416 AYID 419
D
Sbjct: 438 TCAD 441
>gi|78188868|ref|YP_379206.1| dihydroorotase [Chlorobium chlorochromatii CaD3]
gi|78171067|gb|ABB28163.1| Dihydroorotase multifunctional complex type [Chlorobium
chlorochromatii CaD3]
Length = 442
Score = 249 bits (636), Expect = 2e-64, Method: Composition-based stats.
Identities = 143/402 (35%), Positives = 207/402 (51%), Gaps = 34/402 (8%)
Query: 37 DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPD 96
D+ I+ + + + G D H H+REPG KET+ + + AA GGFT V MPN PV D
Sbjct: 46 DDQLINCEGKMIVPGLFDMHCHFREPGQEYKETLESGAEAALAGGFTGVALMPNTRPVID 105
Query: 97 S----------VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIAD-KVFAFT 145
S TL LE+I GA+T E G L+ + V A +
Sbjct: 106 SPLGVAYIRHHSTTLPVDLEVI-----------GAMTVESKGEHLAPYGKFSSYGVTAIS 154
Query: 146 DDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICE 205
DDG +QS+ +M A+ S + I+ HCED SL GG M+EG S LG+KGIP + E
Sbjct: 155 DDGAAIQSSQMMRLALEYASNFDLLIIQHCEDRSLSAGGVMNEGLYSTRLGLKGIPEVAE 214
Query: 206 STQIARDILLAEAANCH----------YHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
+ + RD++L H YHV HIS ++++ VR+ K ++VTCE+TPHH
Sbjct: 215 AITLGRDLMLLRYLEEHKLHTPLRRPRYHVAHISTRQAIELVRQAKMEGLQVTCEITPHH 274
Query: 256 LLSCDEDI--KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGI 313
CD+++ E G + M PPL + R L+A + DGTID IATDHAPH + EK
Sbjct: 275 FTLCDQELFEAERKGNFIMKPPLASQATREHLLAALADGTIDAIATDHAPHALHEKECPP 334
Query: 314 EKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
+++SFGI+G ET+ T+ V+ ++ S+ ++L+S N I L + A+
Sbjct: 335 DQASFGIIGLETSLALTITELVQKEVISMARAIELLSVNPRAIMRLKPIRFAAGEAANFT 394
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
+ID E + E SK NTP+ + G + T G +
Sbjct: 395 IIDPNAEWVVTAEHIRSKSSNTPFIGRTLRGKSLGTFHKGAL 436
>gi|153810616|ref|ZP_01963284.1| hypothetical protein RUMOBE_00997 [Ruminococcus obeum ATCC 29174]
gi|149833795|gb|EDM88876.1| hypothetical protein RUMOBE_00997 [Ruminococcus obeum ATCC 29174]
Length = 430
Score = 249 bits (636), Expect = 3e-64, Method: Composition-based stats.
Identities = 155/426 (36%), Positives = 241/426 (56%), Gaps = 11/426 (2%)
Query: 1 MLLKNCKIL----KNGKFKKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDA 55
MLLKN ++ K +F +DI I++ I KI++++ T E +D+ + G ID
Sbjct: 1 MLLKNGHLIDPTTKTNEF--MDIRIENGIITKIAKDLTSETGEEILDLSGLTIAPGLIDT 58
Query: 56 HVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIR 115
HVH+R+PG + KE ++T S AAA+GGFT+V+ M N P DSV+TL+ L K ++ I
Sbjct: 59 HVHFRDPGLTYKEDIHTGSLAAAKGGFTSVICMANTKPTVDSVDTLSDILNRAKVEN-IH 117
Query: 116 AIPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAH 174
+++ G +++D + +AD FTDDG + +A YEAM + L+ I H
Sbjct: 118 IYQTASVSYGLNGEKMTDFDALADAGACGFTDDGIPLLNATFCYEAMQKAAALHMPISLH 177
Query: 175 CEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESV 234
ED + I ++ G+ SA+LG+ G P+I E +ARD +LA + + HIS+ SV
Sbjct: 178 EEDKAFITNNGINAGETSAQLGVIGSPAIAEEVMVARDCMLALRSGATVVIQHISSGNSV 237
Query: 235 RAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTI 294
VR KK + E TPHH + + E + KMNPPLR +DR +I G+ DGTI
Sbjct: 238 ELVRTAKKLGADIHAEATPHHFTLTEGALLEHGTLAKMNPPLRTEKDRQEIIHGLKDGTI 297
Query: 295 DIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVA 354
D+IATDHAPH+ EEK + + ++ GI G ET+ T VK SL L++ M+ N A
Sbjct: 298 DLIATDHAPHSEEEKAKPLTEAPSGITGLETSLGLGITSLVKEGYLSLMELLEKMTCNPA 357
Query: 355 KIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
++ LP G ++ ++ AD V+ D +++ T+ +F SK N+P+ ++ G ++ + K
Sbjct: 358 FLYKLPGGVIQVHAPADFVIFDPDEKWTVT--DFASKASNSPFKGYELYGKSIIRSAMEK 415
Query: 415 IAYIDK 420
+ DK
Sbjct: 416 LYMKDK 421
>gi|91201691|emb|CAJ74751.1| similar to dihydroorotase [Candidatus Kuenenia stuttgartiensis]
Length = 444
Score = 249 bits (636), Expect = 3e-64, Method: Composition-based stats.
Identities = 158/409 (38%), Positives = 220/409 (53%), Gaps = 25/409 (6%)
Query: 18 DILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
D+L+K+ KIE +S NI ID ++ V G I+ HVH+REPG KE + T SRA
Sbjct: 41 DVLVKNGKIEAVSPNITTNPSVRIIDATNKHVIPGLIECHVHFREPGLEYKEDIRTGSRA 100
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMED 136
AA+GG+TTV+ PN NP DS ++ E I S+I+ ITK EL+D+
Sbjct: 101 AAKGGYTTVICEPNTNPPIDSPAIVDLLTERILEKSIIKVFAKACITKGSLSEELTDIAA 160
Query: 137 IAD--KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL-------IRGGAMH 187
+A ++ A +DDG V + +M +A + + I HCED+ I G
Sbjct: 161 LAKNTRIKALSDDGNPVFNDALMCKACELSVQHAIIISPHCEDSPFYLNKIKDIPGATRF 220
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNI-R 246
G+ P E+ RDI E A H+ HIS K+++ A+++ K+ I +
Sbjct: 221 PGE----------PYSHETDFARRDIRFTEQAKGRLHISHISLKDTLAAIQQAKERGIGK 270
Query: 247 VTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTM 306
TCEVTPHHLL + +D M + NPPLR R D A+ G+ G ID+IATDHAPHT
Sbjct: 271 FTCEVTPHHLLLDNSFRDKDGNMPRTNPPLRSRMDVEAMQNGLASGIIDVIATDHAPHTD 330
Query: 307 EEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEE 366
++ ++K + G VG ETA L TK V T I + + L+ MS N A+IF + G L
Sbjct: 331 DD----LKKGATGFVGLETALGVLLTKLVHTGIITFKELIIKMSVNPARIFQINGGSLAA 386
Query: 367 NSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
ADI +ID KE T++ F SKGRN P+ K+ G + TI NGK+
Sbjct: 387 GMPADITIIDKNKEWTVDVNVFESKGRNCPFHGWKLKGQVLTTIVNGKV 435
>gi|150386853|ref|ZP_01925348.1| dihydroorotase, multifunctional complex type [Victivallis vadensis
ATCC BAA-548]
gi|150256692|gb|EDM94186.1| dihydroorotase, multifunctional complex type [Victivallis vadensis
ATCC BAA-548]
Length = 369
Score = 248 bits (634), Expect = 4e-64, Method: Composition-based stats.
Identities = 142/331 (42%), Positives = 190/331 (57%), Gaps = 1/331 (0%)
Query: 28 KISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMT 87
+I+E +V ID+ + ++ GFID HVH R+PG + ET+ + + AAA GGFT+V+
Sbjct: 30 RIAEASEVRGGEVIDLGGKVLSPGFIDLHVHLRQPGNNMAETIASGTAAAAAGGFTSVVA 89
Query: 88 MPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI-ADKVFAFTD 146
MPN NP D+ + + +V+R +P G +TK G E++ + + A V A +D
Sbjct: 90 MPNTNPPADTAGAIEFLRQTAAKKAVVRVLPCGCMTKGYAGEEMAGIGSLKAAGVVALSD 149
Query: 147 DGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICES 206
DGR +Q +M + N I+ HCED L GG MHEGK S LG+ GI E
Sbjct: 150 DGRCIQDHALMRHVVEYAKSFNLPILDHCEDKCLAAGGVMHEGKWSVLLGMNGISGASEE 209
Query: 207 TQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKED 266
IAR+I+LA H+ H+S KESV +R + I VT E TPHHL DE IK+
Sbjct: 210 LMIARNIILARQIGWKIHMQHVSVKESVELLRNARAKGIPVTGEATPHHLTLTDECIKKY 269
Query: 267 NGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETA 326
+ +KMNPPLR EDR ALIAGV DGTI IATDHAPHTM K+ + + FGI+G ETA
Sbjct: 270 DTNYKMNPPLRSEEDRLALIAGVADGTITAIATDHAPHTMTAKMVEFDYAPFGIIGLETA 329
Query: 327 FTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
Y + V + SL LV+L + A I
Sbjct: 330 LPVSYGELVAKGVISLPKLVELFTAGPADIL 360
>gi|15806126|ref|NP_294830.1| dihydroorotase [Deinococcus radiodurans R1]
gi|9087183|sp|Q9RVC3|PYRC_DEIRA Dihydroorotase (DHOase)
gi|6458840|gb|AAF10679.1|AE001960_7 dihydroorotase [Deinococcus radiodurans R1]
Length = 416
Score = 248 bits (634), Expect = 4e-64, Method: Composition-based stats.
Identities = 143/368 (38%), Positives = 210/368 (57%), Gaps = 3/368 (0%)
Query: 51 GFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKN 110
I+ H H REPG ++KE + + AA+ GG+ TV+ MPN PV D + +E +
Sbjct: 48 ALIELHAHLREPGQTEKEDLASGLAAASAGGYGTVVCMPNTRPVIDDPALVRSLIEKARG 107
Query: 111 DSVIRAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNK 169
R P A+TK E G +L++M + + FTDDG ++A V+ M L
Sbjct: 108 LGFARLRPAAAVTKGEKGEQLTEMSYLKEAGAVMFTDDGLTNENARVLRLGMEYAKSLGM 167
Query: 170 AIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHIS 229
I H ED++L GG M+EG S LG+ G P+ + ++ARD+ + HV H+S
Sbjct: 168 VISVHAEDDALRAGGVMNEGPVSESLGLPGNPAAAAAARVARDMEIVALTGARLHVQHLS 227
Query: 230 AKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGV 289
+ VR+ K+ + VTCEV PHHL DE ++ + M+K+ PPLR R D + L+ G+
Sbjct: 228 TARELDIVRDAKRRGLPVTCEVCPHHLDLTDESLRTFDAMYKVAPPLRTRADADYLLEGL 287
Query: 290 LDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLM 349
LDG++D IATDHAPHT EK R + + GI E AF ++T+F + LE L+ LM
Sbjct: 288 LDGSVDCIATDHAPHTRAEKERDLLDAPSGIAYIEIAFPIMWTRF--GERLGLEKLIDLM 345
Query: 350 SENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLT 409
+ A++ P LE + AD+VV+DLE E +NP EF SK + TP+ +K+ G P+LT
Sbjct: 346 TAGPARVMGWPEPSLEAGAPADMVVLDLETEREVNPAEFKSKAKFTPWQGQKLRGFPLLT 405
Query: 410 ISNGKIAY 417
+ +GK+AY
Sbjct: 406 VVDGKVAY 413
>gi|62426348|ref|ZP_00381476.1| COG0044: Dihydroorotase and related cyclic amidohydrolases
[Brevibacterium linens BL2]
Length = 439
Score = 248 bits (633), Expect = 5e-64, Method: Composition-based stats.
Identities = 150/407 (36%), Positives = 214/407 (52%), Gaps = 9/407 (2%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKI-EKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
L++ +L G DI IKD I + + D T + + G +D H H R
Sbjct: 5 LIRGANVLGQGS---ADIAIKDSTIVDPDLLDPDDTSVEVVSAEGLIALPGLVDMHTHLR 61
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG ET+ + SRAAA GGFT V M N PV D+ + + + + +P G
Sbjct: 62 EPGKEDAETILSGSRAAAAGGFTCVHAMANTAPVADTAGVVEQVHRLGRTAGYTEVVPIG 121
Query: 121 AITKEEYGRELSD---MEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
A+T G+ L++ M A +V F+DDG V +M A+ + I H ++
Sbjct: 122 AVTIGLEGKNLAEIGAMARSAARVRIFSDDGICVSDPLLMRRALEYVKTFDGVIAQHAQE 181
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L G M+EG SAELG+ G P++ E + IARD+LLAE H+CH+S K SV +
Sbjct: 182 PRLTEGAQMNEGVVSAELGLPGWPAVAEESIIARDVLLAEHVGSRLHICHVSTKGSVDII 241
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K + +T EVTPHHL+ DE ++ + ++K+NPPLR D AL + DGTID+I
Sbjct: 242 RWAKSRGVEITAEVTPHHLMLTDELVRSFDPVYKVNPPLRTEADVTALREALADGTIDVI 301
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
TDHAPHT E K ++ G+VG ETA + + D F L ++MS A+I
Sbjct: 302 GTDHAPHTAEHKCSEWTAAAMGMVGMETALSIVVEAMADYD-FDYGDLARVMSVTPARIT 360
Query: 358 NLP-YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVN 403
+G LE S A+IV+ID TI P++ +KGRN P+A +V+
Sbjct: 361 GATGHGSLEIGSSANIVLIDPNSTHTIVPDDHATKGRNNPFAGLEVS 407
>gi|116749522|ref|YP_846209.1| dihydroorotase, multifunctional complex type [Syntrophobacter
fumaroxidans MPOB]
gi|116698586|gb|ABK17774.1| dihydroorotase, multifunctional complex type [Syntrophobacter
fumaroxidans MPOB]
Length = 439
Score = 248 bits (633), Expect = 6e-64, Method: Composition-based stats.
Identities = 144/406 (35%), Positives = 213/406 (52%), Gaps = 7/406 (1%)
Query: 18 DILIKDDKIEKISENIDVTDEN-----TIDVKDRFVTAGFIDAHVHWREPGFSKKETVYT 72
D+L+ D + I NID+ + ID ++++ G ID HVH REPG KET+ T
Sbjct: 30 DVLVVDGILTDIKPNIDLPSDRLAHFAVIDASEKWIVPGLIDMHVHLREPGEEYKETIAT 89
Query: 73 ASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELS 132
+ AA GG+T V MPN PV D LE + R +P GA++ GR L+
Sbjct: 90 GTMAAVAGGYTAVACMPNTKPVNDCAAVTEYILERAREQGHCRVLPVGAVSSGLEGRSLA 149
Query: 133 DMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKR 191
+ ++ A TDDGR V ++ +M A+ + +++H ED +L GG M+EG
Sbjct: 150 EFGELKGSGAVAVTDDGRPVANSMLMRRALEYAKNFDLPVISHAEDPALSEGGLMNEGPT 209
Query: 192 SAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEV 251
S LG+ GIP E +ARD+ LAE H+ H+S +VR + E K + VT E
Sbjct: 210 STLLGLHGIPKAAEEVMVARDLALAELTGARLHIAHVSTAGAVRMIGEAKSRGVPVTAET 269
Query: 252 TPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIR 311
PH+ D+ + + ++K+NPP+RG D A+ G+ DGTID +ATDHAPH+ EK
Sbjct: 270 APHYFTLTDDRLMTFDTLYKVNPPIRGPADVEAIKRGLADGTIDAVATDHAPHSSIEKDT 329
Query: 312 GIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFAD 371
E ++ GI+G E+A L + V+ + V +S N A+I LP G L N A
Sbjct: 330 EFEYAANGIIGLESALP-LILELVREKTLTPSQAVAKVSCNPARILGLPLGTLLLNQRAC 388
Query: 372 IVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+ +D E ++ F SK RN P+ + G ++T NGK+A+
Sbjct: 389 MTYLDPEFYFVLDCTTFRSKSRNCPFHGQPTRGRALMTFFNGKVAF 434
>gi|38233919|ref|NP_939686.1| dihydroorotase [Corynebacterium diphtheriae NCTC 13129]
gi|38200180|emb|CAE49861.1| dihydroorotase [Corynebacterium diphtheriae]
Length = 448
Score = 248 bits (632), Expect = 7e-64, Method: Composition-based stats.
Identities = 153/426 (35%), Positives = 228/426 (53%), Gaps = 8/426 (1%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN KI G+ V++LI D I DV + +D + + G +D HVH R
Sbjct: 20 LLVKNVKIYGEGE--PVNVLITDGVITDTHAG-DVKADREVDGQGGVLLPGLVDIHVHLR 76
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG ET+ T S AAA+GGFT V TM N PV D ++ + P G
Sbjct: 77 EPGREDTETIATGSAAAAKGGFTAVFTMANTMPVMDQPIIAESVWHKGQDIGLCDVHPVG 136
Query: 121 AITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
+ITK G+E+++ +A KV F+DDG+ V + +M A+ + + HCED
Sbjct: 137 SITKGLEGKEITEFGMMAHSQAKVRMFSDDGKCVDNPLIMRRAVEYARGTDVLLAQHCED 196
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L G HEG +A+LG+ G P + E + +ARD +LA H+CH S + +V V
Sbjct: 197 PRLTDGAVAHEGAMAAKLGLGGWPRVAEESIVARDAILARDYGGRMHICHASTQGTVELV 256
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ K++ I +T EVTPHHLL DE + +G+ ++NPPLR D AL +L+GTID +
Sbjct: 257 KWAKEHEIPLTAEVTPHHLLLTDERLATYDGVNRVNPPLRENSDILALRDALLNGTIDCV 316
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH E+K E + G++G ET+ + FV+T + + K+MSE A+I
Sbjct: 317 ATDHAPHGSEDKCCEFEHAKPGMLGLETSLAVVAAVFVETGLADWRFVAKVMSERPAEIV 376
Query: 358 NLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
LP +G+ + A++ ++D + T + E+ SK NTPY + N TI G++
Sbjct: 377 KLPGHGRPIAVGEPANLTIVDPGAKWTASGEKMASKATNTPYEGMEFNARVTTTILRGRL 436
Query: 416 AYIDKE 421
+D E
Sbjct: 437 TCVDGE 442
>gi|121541592|ref|ZP_01673341.1| Dihydroorotase [Candidatus Desulfococcus oleovorans Hxd3]
gi|121518478|gb|EAX55337.1| Dihydroorotase [Candidatus Desulfococcus oleovorans Hxd3]
Length = 429
Score = 248 bits (632), Expect = 7e-64, Method: Composition-based stats.
Identities = 154/407 (37%), Positives = 224/407 (55%), Gaps = 9/407 (2%)
Query: 18 DILIKDDKIEKISENID--VTDENT---IDVKDRFVTAGFIDAHVHWREPGFSKKETVYT 72
DI+I D KI I E+ V E ID + V G ID HVH+REPG+ KET+ T
Sbjct: 20 DIVIADGKIRGIVESATGAVPAEGVSRWIDASGKIVAPGLIDMHVHFREPGYEYKETIAT 79
Query: 73 ASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSV-IRAIPYGAITKEEYGREL 131
AAARGGF V MPN +PV D + K V ++ P GA++ + G+EL
Sbjct: 80 GCAAAARGGFAAVCPMPNTDPVNDHAQVCEFVRGRAKACGVGVKVWPVGAVSVGQAGKEL 139
Query: 132 SDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGK 190
++ ++ A A +DDG V +M A+ +++HCE+ SL+ G M+EG
Sbjct: 140 AEFGELKAAGAVALSDDGHPVSDGQLMRRALEYARGFGLPVISHCEELSLVGPGVMNEGA 199
Query: 191 RSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
+A LG+ GIP+ ES + RD+ L E H+ H+S ESVR VRE KK + VT E
Sbjct: 200 FAARLGLAGIPNAAESVMVCRDVALCELTGAALHIAHVSTAESVRIVREAKKRGVPVTAE 259
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
PH + DE + + K+NPPLR DR A+ G+ DGTID+IA DHAPH++ EK
Sbjct: 260 TAPHFFMLTDEAVGLYDTSAKVNPPLRSMADREAIREGLADGTIDVIACDHAPHSVLEKE 319
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFA 370
+ ++ GI G ET+ L V ++ S+ L+ MS A+I P+G L+E S A
Sbjct: 320 VEFDAAANGISGIETSLG-LCLSLVNDNVLSMAGLIDKMSMAPARILGKPWG-LKEGSPA 377
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
I +I + +N + F S G+NTP+ +++G V+TI++G++ +
Sbjct: 378 HITIIAPDSPWVVNAKTFFSLGKNTPFDGWELSGRAVMTIADGRVIF 424
>gi|68548958|ref|ZP_00588426.1| Dihydroorotase multifunctional complex type [Pelodictyon
phaeoclathratiforme BU-1]
gi|68244089|gb|EAN26282.1| Dihydroorotase multifunctional complex type [Pelodictyon
phaeoclathratiforme BU-1]
Length = 442
Score = 246 bits (628), Expect = 2e-63, Method: Composition-based stats.
Identities = 146/391 (37%), Positives = 203/391 (51%), Gaps = 34/391 (8%)
Query: 37 DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPD 96
++ ID++ + G D H H+REPG KET+ + S+AA GGFT V MPN PV D
Sbjct: 46 EDRVIDLQGLILAPGLFDMHCHFREPGQEYKETLESGSKAAVTGGFTGVALMPNTKPVID 105
Query: 97 S----------VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIAD-KVFAFT 145
+ TL +E+I GA+T E G L+ + V A +
Sbjct: 106 NPTGVAYIRHHAATLPIDIEVI-----------GAMTVESKGEHLAPFGKFSSYGVTAVS 154
Query: 146 DDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICE 205
DDG +Q++ +M A S + I+ HCED SL G M+EG S +LG+KGIP I E
Sbjct: 155 DDGSAIQNSQIMRLAFEYASNFDLLIIQHCEDRSLTVGAVMNEGLFSTQLGLKGIPDISE 214
Query: 206 STQIARDILLAEAANCH----------YHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
+ ++RD+LL H YHV HIS K S+ VR+ K + ++VTCEVTPHH
Sbjct: 215 AIMLSRDLLLMHYLEQHKLHDPLRRARYHVAHISTKASLDLVRKAKLDGLQVTCEVTPHH 274
Query: 256 LLSCDEDI--KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGI 313
CDED+ E G + M PPL RE+R AL+ + DGTID IATDHAPH EK
Sbjct: 275 FTLCDEDLFHAELKGNYIMKPPLSSRENREALLEALADGTIDAIATDHAPHASHEKECPS 334
Query: 314 EKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
++ +FGI G E++ T+ V +I SL ++L+S N KI L A+
Sbjct: 335 DQVAFGITGLESSLGLTITELVDKNIISLSRAIELLSVNPRKIMRLKPILFAPGEKANFT 394
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNG 404
+ID + ++ SK NTP+ + + G
Sbjct: 395 IIDPDARWSLTASSLKSKSSNTPFIDRPLKG 425
>gi|67917689|ref|ZP_00511294.1| Dihydroorotase multifunctional complex type [Chlorobium limicola
DSM 245]
gi|67784718|gb|EAM44092.1| Dihydroorotase multifunctional complex type [Chlorobium limicola
DSM 245]
Length = 440
Score = 246 bits (627), Expect = 3e-63, Method: Composition-based stats.
Identities = 141/384 (36%), Positives = 205/384 (53%), Gaps = 20/384 (5%)
Query: 37 DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPD 96
D+ ID+ + + G D H H+REPG KET+ T S AAA GG+T V MPN PV D
Sbjct: 46 DDRVIDLDGKLLVPGLFDMHCHFREPGQEYKETLETGSSAAAAGGYTGVALMPNTRPVID 105
Query: 97 SVETLNKQLEIIKNDSVIRAIPY---GAITKEEYGRELSDMEDIAD-KVFAFTDDGRGVQ 152
S + I++ S + + GA+T E G L+ V A +DDG +Q
Sbjct: 106 S----PLGVAYIRHHSALLPVDLEVIGAMTVESRGETLAPFGKFRSYGVTAISDDGTAIQ 161
Query: 153 SANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARD 212
+ +M A S + I+ HCED +L +GG M+E S LG+KGIP + E+ ++RD
Sbjct: 162 NTQIMRLAFEYASNFDLLIIQHCEDKTLTKGGVMNESHFSTILGLKGIPDVAEAIIVSRD 221
Query: 213 ILLAEAANCH----------YHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDED 262
+ L H YHV HIS ++ VR+ K + ++VTCEVTPHH DED
Sbjct: 222 LQLMRYLQQHKLHDPLNQPRYHVAHISTGAALDLVRQAKLDGLQVTCEVTPHHFTLSDED 281
Query: 263 I--KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGI 320
+ E G + M PPL E+ ALI + DGTID IATDHAPH EK ++++FGI
Sbjct: 282 LFLAEAKGNFIMKPPLGSAENMQALIDAIADGTIDAIATDHAPHAAHEKDCPPDQAAFGI 341
Query: 321 VGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKE 380
G ETA T+ V ++ +++ ++++S N KI NL A++ +ID E E
Sbjct: 342 TGLETAVGLTLTELVSKNVITMQRAIEMLSVNPRKIMNLAPVHFRAGEMANMTIIDPEVE 401
Query: 381 ITINPEEFLSKGRNTPYANEKVNG 404
T+ ++ S+ +NTP+ ++ G
Sbjct: 402 WTVTKDDMKSRSQNTPFIGRRLKG 425
>gi|88856238|ref|ZP_01130898.1| dihydroorotase [marine actinobacterium PHSC20C1]
gi|88814557|gb|EAR24419.1| dihydroorotase [marine actinobacterium PHSC20C1]
Length = 438
Score = 245 bits (625), Expect = 4e-63, Method: Composition-based stats.
Identities = 141/386 (36%), Positives = 210/386 (54%), Gaps = 15/386 (3%)
Query: 38 ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDS 97
+ TID G +D H H REPGF + ETV + +RAAA GGFT V M N PV D+
Sbjct: 32 DRTIDAAGLQALPGLVDLHTHLREPGFEQSETVLSGTRAAAMGGFTAVFAMANTLPVQDT 91
Query: 98 VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSA 154
+ + + + P GA+T+ G +LS++ +A+ +V F+DDG+ V +A
Sbjct: 92 AGVVEQVQSLGDSHGFATVRPIGAVTERLAGEKLSEIGAMANSRARVRVFSDDGKCVHNA 151
Query: 155 NVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDIL 214
+M A+ + + H ++ +L M+EG S+ELG+ G P++ E + IARD+L
Sbjct: 152 LLMRRALEYVKTFDGVVAQHAQEPTLTLDAQMNEGAVSSELGLAGWPAVAEESIIARDVL 211
Query: 215 LAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNP 274
LAE H+CH+S SV +R K I VT EVTPHHLL +E ++ + +K+NP
Sbjct: 212 LAEHVGARLHICHLSTAGSVDVIRWAKARGIAVTAEVTPHHLLLTEELVRGYDARFKVNP 271
Query: 275 PLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKF 334
PLR ED +AL A + DGTIDI+ATDHAPH E K +++FG+VG E+A +
Sbjct: 272 PLRRDEDVHALRAALADGTIDIVATDHAPHPPEAKECSWAEAAFGMVGLESALNVVQEAV 331
Query: 335 VKTDIFSLEMLVKLMSENVAKIFNLPYGKLEE-------NSFADIVVIDLEKEITINPEE 387
V T + + +++S+ A+I G+LE S A++V++D T N +
Sbjct: 332 VDTGQLTWADVARVLSQKPAQI-----GRLEGYDRPFALGSVANLVLVDPSARSTFNTDS 386
Query: 388 FLSKGRNTPYANEKVNGIPVLTISNG 413
K N+PY + G + TI NG
Sbjct: 387 LRGKSANSPYLGRDLPGRIMTTIHNG 412
>gi|156863623|gb|EDO57054.1| hypothetical protein CLOL250_02240 [Clostridium sp. L2-50]
Length = 429
Score = 245 bits (625), Expect = 4e-63, Method: Composition-based stats.
Identities = 153/427 (35%), Positives = 226/427 (52%), Gaps = 15/427 (3%)
Query: 1 MLLKNCKILK--NGKFKKVDILIKDDKIEKISENID---------VTDENTIDVKDRFVT 49
+L+KN +++ +K+D+L+ I ++ + ID D ID + V
Sbjct: 2 LLIKNGRVVDPVTNTDRKLDVLVDGAVITEVEQQIDPEACREKYGTGDVRVIDAEGLVVA 61
Query: 50 AGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIK 109
G +D HVH+R+PGF+ KE + T + AAA GGFTTV+ M N P D+VETL + ++
Sbjct: 62 PGLVDTHVHFRDPGFTYKEDIETGAEAAAYGGFTTVICMANTKPAVDNVETL-EYIQRKG 120
Query: 110 NDSVIRAIPYGAITKEEYGRELSDMEDIADKVFA-FTDDGRGVQSANVMYEAMLMGSKLN 168
+ I I +TK+ G+EL DME +A+ A FTDDG + V+ EAML L+
Sbjct: 121 ETTGIHVIQTATVTKDLKGKELVDMELLAEHGAAGFTDDGIPIMDEEVLTEAMLRAKALD 180
Query: 169 KAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHI 228
I H ED + ++G ++ G S +LG G E +ARD +LA + HI
Sbjct: 181 LPISLHEEDPAFVKGAGVNMGAVSEQLGYGGASRTAEDVMVARDCILALHTGASVCIQHI 240
Query: 229 SAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAG 288
S+ SV VR KK V E TPHH ++ + M +MNPP+R DR +I G
Sbjct: 241 SSGNSVELVRLAKKLGADVHAEATPHHFTLTEDAVLTYGTMARMNPPVREEADRLKIIEG 300
Query: 289 VLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKL 348
+ DGTID+I TDHAPH+ EEK R + ++ GI G ET+ V+ +L L++L
Sbjct: 301 IQDGTIDMIVTDHAPHSAEEKARPMAQAPSGITGLETSLALGIRSLVQPGYITLMKLMEL 360
Query: 349 MSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVL 408
MS+N + + + G ++ + ADIV+ +E + E F SK N+P+ + G
Sbjct: 361 MSKNPMEFYRMTPGSIQAGAPADIVIFGENEEWIV--EHFHSKASNSPFLGWTLPGKLHY 418
Query: 409 TISNGKI 415
TI NGKI
Sbjct: 419 TICNGKI 425
>gi|21673868|ref|NP_661933.1| dihydroorotase [Chlorobium tepidum TLS]
gi|28201863|sp|Q8KDK5|PYRC_CHLTE Dihydroorotase (DHOase)
gi|21647003|gb|AAM72275.1| dihydroorotase [Chlorobium tepidum TLS]
Length = 439
Score = 245 bits (625), Expect = 5e-63, Method: Composition-based stats.
Identities = 150/402 (37%), Positives = 208/402 (51%), Gaps = 34/402 (8%)
Query: 37 DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPD 96
++N ID+ + + G D H H+REPG KET+ T S AA GGFT V MPN PV D
Sbjct: 46 EDNVIDLAGKVLAPGLFDMHCHFREPGQEYKETLETGSAAAVAGGFTGVALMPNTRPVID 105
Query: 97 S----------VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIAD-KVFAFT 145
S L LE+I GA+T E G L+ A V A +
Sbjct: 106 SPLGVAYIRHHSAGLPIDLEVI-----------GAMTVESRGEALAPYGKYASYSVKAVS 154
Query: 146 DDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICE 205
DDG +QS+ +M A+ + + ++ H ED L GG M++G SA LG+KGIP + E
Sbjct: 155 DDGTAIQSSQIMRLAIEYAANFDLLLIQHAEDKHLTAGGIMNDGAVSAMLGLKGIPEVAE 214
Query: 206 STQIARDILL----------AEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
IARD+ L A YHV HIS ESV VR+ K ++VTCEVTPHH
Sbjct: 215 PIMIARDLQLIAWLKKHKLNGAVAEPRYHVAHISTAESVALVRKAKAAGLKVTCEVTPHH 274
Query: 256 LLSCDEDIKE--DNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGI 313
+ D+ + G + M PPL E+R+ALI G+ DGTID IATDHAPH EK
Sbjct: 275 FTLTEHDLSSSIEKGNFIMKPPLASVENRDALIEGLRDGTIDAIATDHAPHAKHEKECPP 334
Query: 314 EKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
++++FGI+G ET+ T+ V + +L ++L+S N +I L A++
Sbjct: 335 DQAAFGIIGLETSLGLTITELVDKGVITLSQAIELLSTNPRRIMGLETILFRAGRKANLT 394
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
+ID + E ++ +F SK RNTP+ K+ G + N K+
Sbjct: 395 IIDPDCEWIVSESDFGSKSRNTPFMGRKLKGRALGIYHNSKL 436
>gi|28211974|ref|NP_782918.1| dihydroorotase [Clostridium tetani E88]
gi|28204417|gb|AAO36855.1| dihydroorotase [Clostridium tetani E88]
Length = 396
Score = 244 bits (624), Expect = 6e-63, Method: Composition-based stats.
Identities = 146/417 (35%), Positives = 239/417 (57%), Gaps = 27/417 (6%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN +++ + D+ IKD I +I +++ + TID + + FID H H+R
Sbjct: 3 LLIKNSRVVDFLQDFIGDVYIKDGIIHEIGRDLE-KNCKTIDGIGKVLMPSFIDLHAHFR 61
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG++ KE + + SRAAA+GG+T V MPN NPV S++ +N + +I
Sbjct: 62 EPGYTYKEDIESGSRAAAKGGYTYVNLMPNTNPVCSSMDIVNYVINKADEIGLIDVHQAV 121
Query: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
+IT++ G+ ++ ++++ +KV ++DG+ V ++ M +AM + N ++ HCE++ +
Sbjct: 122 SITRDFDGQTINHIDELDEKVKVISEDGKDVMNSKTMIKAMEKAKEKNILVMCHCENHDI 181
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
AM + E T R+I LA+ C H+ H+S K+S+ + +
Sbjct: 182 ---SAMDM-------------RLAEDTMTWRNITLAQYTGCPVHISHVSTKKSMNYIIDA 225
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
K+ VTCEVTPHH+ ED+ +++NPPLR +EDR+ LI + +G +D I TD
Sbjct: 226 KRKGQNVTCEVTPHHI------ALEDDINYRVNPPLRKKEDRDFLIKTIREGLVDAIGTD 279
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPH+ E+K +G S GI G ET F+ Y+ VK SL L ++MS+N ++I NL
Sbjct: 280 HAPHSYEDKTKG----SPGISGIETVFSVCYSYLVKKKEISLSKLSEIMSKNPSEIMNLN 335
Query: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+++ D+V+++LEK +N + FLSKG+NTP+ +K+ G TI +GKI Y
Sbjct: 336 KGQIKIGFMGDLVLVNLEKSYKVNSDSFLSKGKNTPFEGKKLYGQVEKTIKSGKIIY 392
>gi|145219707|ref|YP_001130416.1| dihydroorotase, multifunctional complex type [Prosthecochloris
vibrioformis DSM 265]
gi|145205871|gb|ABP36914.1| dihydroorotase, multifunctional complex type [Prosthecochloris
vibrioformis DSM 265]
Length = 439
Score = 243 bits (621), Expect = 2e-62, Method: Composition-based stats.
Identities = 149/401 (37%), Positives = 215/401 (53%), Gaps = 34/401 (8%)
Query: 38 ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDS 97
E I+++ R ++ G D H H+REPG KET+ + + AAA GGFT V MPN PV DS
Sbjct: 47 ERIIEMEGRILSPGLFDMHCHFREPGQEYKETLESGAAAAAAGGFTGVALMPNTRPVIDS 106
Query: 98 ----------VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIAD-KVFAFTD 146
L LE+I GA+T E G L+ A V A +D
Sbjct: 107 PLGVAFIRHHAGGLPVDLEVI-----------GAMTVESRGEGLAPFGKYASYGVTAVSD 155
Query: 147 DGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICES 206
DG +Q++ +M A S N ++ HCED SL GG ++EG S +LG+KGIP I E+
Sbjct: 156 DGSAIQNSQIMRLAFEYASNFNLLVIQHCEDRSLTAGGVVNEGMYSTQLGLKGIPDISEA 215
Query: 207 TQIARDILLAEAANCH----------YHVCHISAKESVRAVREGKKNNIRVTCEVTPHHL 256
+ARD+LL H YH HIS + S+ +R+ KK+ + VTCEVTPHH
Sbjct: 216 MMLARDLLLLRWLEEHKLHDPLQRPRYHAAHISTEASLNLIRQAKKDGLLVTCEVTPHHF 275
Query: 257 LSCDEDI--KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIE 314
CDED+ E+ G + M PPL +R AL+ + DGT+D IATDHAPH EK +
Sbjct: 276 TLCDEDMFNAEEKGNYIMKPPLSSARNREALLEALRDGTVDAIATDHAPHASHEKQCPPQ 335
Query: 315 KSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVV 374
+++FGI+G ET+ ++ V+ +I S++ ++L+S N KI NL +E S A+ +
Sbjct: 336 EAAFGIIGLETSVGLTISQLVERNIISIQRAIELLSVNPRKIMNLQPISFKEGSVANFTL 395
Query: 375 IDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
ID E + ++ SK NTP+ + + G + G++
Sbjct: 396 IDPLIEWKVTADKLHSKSINTPFIGKTLKGKAIGIYHKGRL 436
>gi|156719232|ref|ZP_02060876.1| dihydroorotase, multifunctional complex type [Hydrogenobaculum sp.
Y04AAS1]
gi|156710507|gb|EDO50872.1| dihydroorotase, multifunctional complex type [Hydrogenobaculum sp.
Y04AAS1]
Length = 424
Score = 243 bits (620), Expect = 2e-62, Method: Composition-based stats.
Identities = 153/424 (36%), Positives = 229/424 (54%), Gaps = 14/424 (3%)
Query: 1 MLLKNCKILK-NGKF-KKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+K+ ++++ N F K+VDILIKDDKI+KISE ID D NT++ K +GF+D H H
Sbjct: 5 LLIKSARLIEPNLNFDKEVDILIKDDKIDKISEYIDKKDYNTVEAKGLIACSGFVDIHAH 64
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
R+PGF+ KE + + +AA GGFTT++ MPN NP D+ ++ L + +
Sbjct: 65 LRDPGFTYKEDLESGMKAATFGGFTTIVCMPNTNPPIDNESIISYILSKAEKIGICDVKV 124
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
+TK G+EL+D + FTDDG VQ +M +A+ M S LN + HCED
Sbjct: 125 SACVTKNRSGKELTDFYRLKKAGTVCFTDDGSPVQDQKLMLKALEMVSLLNSFVANHCED 184
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
++ GA EG S+ G+ PS E +ARD +L+ H+ H+S+ SV V
Sbjct: 185 DAFAGNGAFDEGAFSSVYGLPFRPSYAEDVMVARDCILSYKTGGKLHIQHLSSSLSVDIV 244
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ K+ +TCEV P+HL + + K+NPP+R + + ALI + +G ID I
Sbjct: 245 KFFKEKGANITCEVNPNHLALNSFAAFKKKTILKVNPPIRDYKTQEALIKALQEGVIDCI 304
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH EK+ I K + G++G + A + VK + ++ L+ LMS+N AKI
Sbjct: 305 ATDHAPHAKNEKLHPI-KGAAGMLGFQVALP-IIMSLVKDGVIDIKSLITLMSKNPAKIL 362
Query: 358 NLPYGKLEENSFADIVVIDLEKEI----TINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
++E + A++V+ E +INP SK N+P+ N + TI G
Sbjct: 363 GFD-NTIKEGALANLVLWHPSHEWLFDESINP----SKSSNSPFLNSVLTSKVFYTIYKG 417
Query: 414 KIAY 417
I Y
Sbjct: 418 NIVY 421
>gi|120403645|ref|YP_953474.1| dihydroorotase, multifunctional complex type [Mycobacterium
vanbaalenii PYR-1]
gi|119956463|gb|ABM13468.1| dihydroorotase, multifunctional complex type [Mycobacterium
vanbaalenii PYR-1]
Length = 442
Score = 243 bits (620), Expect = 2e-62, Method: Composition-based stats.
Identities = 147/425 (34%), Positives = 221/425 (52%), Gaps = 8/425 (1%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHVHW 59
++LK+ ++ G VD+L++D +I +I E + TD ++ID + + + GF+D H H
Sbjct: 15 IVLKSVRLYGEGD--PVDVLVRDGQIAEIGERLTAPTDADSIDCEGKILLPGFVDLHTHL 72
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG E + T S AAA GG+T V M N +PV DS + + ++ P
Sbjct: 73 REPGREYAEDIETGSAAAALGGYTAVFAMANTDPVADSAVVTDHVWHRGQQVGLVDVHPV 132
Query: 120 GAITKEEYGRELSDMEDIA---DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
GA+T G++L++M +A +V F+DDG V VM A+ S L I H E
Sbjct: 133 GAVTVGLDGKQLTEMGLMAAGAGQVRMFSDDGVCVDDPLVMRRALEYASGLGVLIAQHAE 192
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
+ L G HEG +A LG+ G P E + +ARD LLA A H+CH S +V
Sbjct: 193 EPRLTVGAVAHEGPNAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTAGTVEL 252
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
++ K I +T EVTPHHLL D + +G+ ++NPPLR D AL + DG ID
Sbjct: 253 LKWAKSQGISITAEVTPHHLLLDDSRLDTYDGVNRVNPPLREVSDAVALRRALADGVIDC 312
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
+ATDHAPH EK + G++G +TA + + V + + + ++MSE A+I
Sbjct: 313 VATDHAPHGAHEKCCEFANARPGMLGLQTALSVVVETLVNPGLLTWRDVARVMSEAPARI 372
Query: 357 FNLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
LP G+ LE A++ V+D T+ E S+ NTPY + ++ + T+ GK
Sbjct: 373 VGLPDQGRPLEVGEPANLTVVDPAARWTVKGPELASRSDNTPYEDMELPAVVTATLLRGK 432
Query: 415 IAYID 419
+ D
Sbjct: 433 VTARD 437
>gi|110801777|ref|YP_698522.1| dihydroorotase, multifunctional complex type [Clostridium
perfringens SM101]
gi|110682278|gb|ABG85648.1| dihydroorotase, multifunctional complex type [Clostridium
perfringens SM101]
Length = 399
Score = 243 bits (619), Expect = 2e-62, Method: Composition-based stats.
Identities = 153/419 (36%), Positives = 228/419 (54%), Gaps = 28/419 (6%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN ++ DI I+ I+++ ++ E T+D K + FID H H+R
Sbjct: 3 LLIKNVNLIDESNNFFGDIYIEKGVIKELGTELNKECE-TLDGKGLVLMPAFIDTHAHFR 61
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
+PGF KE + + S+AA RGG+TTV MPN PV S E L+ + K ++
Sbjct: 62 DPGFEYKEDIESGSKAAVRGGYTTVTLMPNTKPVCSSKEILDYVVNKGKEVDLVDLYQTV 121
Query: 121 AITKEEYGRELSDMEDIADK--VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+ITK G E++ + + V A TDDG+GV + +M EAM + + N +++H E
Sbjct: 122 SITKNLSGEEINHLREFEGNPNVKAITDDGKGVSDSKIMMEAMKIAKENNWIVMSHAE-- 179
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
S E K + E+ RDI LA+ +C H+ H+S KE+++ +
Sbjct: 180 -------------SPEFS-KVDMRLAENMMTWRDITLAKFIDCRLHMSHVSTKEAMKYII 225
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
EGK + ++VTCE+TPHHL + +++NPP+R ED N LI + +D I
Sbjct: 226 EGKNDGVKVTCEITPHHLA-----LNNKISNYRVNPPIREEEDVNFLIKAIKMNYVDCIG 280
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH+ E+K EK + G++G E AF+ YTK VK + SL L +LMS N AK+ N
Sbjct: 281 TDHAPHSKEDK----EKGAPGMIGIEQAFSICYTKLVKENHISLNKLSQLMSGNAAKLLN 336
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L GKL+ D+V+IDL K+ E+ +S+ +NTP+ + G VLTI NGKI Y
Sbjct: 337 LNKGKLQPGFLGDLVLIDLNKKRIFKEEDIVSRSKNTPFNGMEFYGDVVLTIKNGKIVY 395
>gi|18310163|ref|NP_562097.1| dihydroorotase [Clostridium perfringens str. 13]
gi|18144842|dbj|BAB80887.1| dihydroorotase [Clostridium perfringens str. 13]
Length = 399
Score = 242 bits (618), Expect = 3e-62, Method: Composition-based stats.
Identities = 149/419 (35%), Positives = 226/419 (53%), Gaps = 28/419 (6%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN ++ DI I+ I+++ ++ E T+D K + FID H H+R
Sbjct: 3 LLIKNVNLIDESNNFFGDIYIEKGVIKELGTELNKECE-TLDGKGLVLMPAFIDTHAHFR 61
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
+PGF KE + + S+AA RGG+TTV MPN PV S E L+ + K ++
Sbjct: 62 DPGFEYKEDIESGSKAAVRGGYTTVTLMPNTKPVCSSKEILDYVVNKGKEVGLVDLYQTV 121
Query: 121 AITKEEYGRELSDMEDIADK--VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+ITK G E++ + + V A TDDG+GV + +M EAM + + N +++H E
Sbjct: 122 SITKNLSGEEINHLREFEGNPNVKAITDDGKGVSDSKIMMEAMKIAKENNWIVMSHAESP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
R + E+ RDI LA+ +C H+ H+S KE+++ +
Sbjct: 182 EFSRVDM----------------RLAENMMTWRDITLAKFVDCRLHMSHVSTKEAMKYII 225
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
EGK + ++VTCE+TPHHL + +++NPP+R ED N LI + +D I
Sbjct: 226 EGKNDGVKVTCEITPHHLA-----LNNKISNYRVNPPIREEEDVNFLIKAIKMNYVDCIG 280
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH+ E+K EK + G++G E AF+ YTK VK + SL L +LMS N AK+ N
Sbjct: 281 TDHAPHSKEDK----EKGAPGMIGIEQAFSICYTKLVKENHISLNKLSQLMSGNAAKLLN 336
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+ GKL+ D+V+IDL K+ E+ +S+ +NTP+ + G V+TI NGKI Y
Sbjct: 337 INKGKLQPGFLGDLVLIDLNKKRIFKEEDIVSRSKNTPFNGMEFYGDVVVTIKNGKIVY 395
>gi|68552959|ref|ZP_00592342.1| Dihydroorotase multifunctional complex type [Prosthecochloris
aestuarii DSM 271]
gi|68240100|gb|EAN22378.1| Dihydroorotase multifunctional complex type [Prosthecochloris
aestuarii DSM 271]
Length = 440
Score = 241 bits (616), Expect = 5e-62, Method: Composition-based stats.
Identities = 140/399 (35%), Positives = 213/399 (53%), Gaps = 22/399 (5%)
Query: 38 ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDS 97
+ ID+ + + G D H H+REPG KET+ T SRAA GGFT V MPN PV D+
Sbjct: 47 DRVIDMNGKLLVPGLFDMHCHFREPGQEYKETLETGSRAAVAGGFTGVALMPNTKPVIDN 106
Query: 98 VETL----NKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQ 152
+ + +E+ + VI A+TKE G L+ + A V A +DDG +Q
Sbjct: 107 PQGVAYIRQTAMELPIDIEVI-----SAMTKESRGETLAPFGKLFASGVKAVSDDGTAIQ 161
Query: 153 SANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARD 212
++ +M A + N + HCED SL GG M+EG+ SA +G+KGIP + E+ ++RD
Sbjct: 162 NSQIMRLAFEYAANFNLLFIQHCEDTSLTSGGVMNEGEYSAMMGLKGIPDVAEAITLSRD 221
Query: 213 ILLAEAANCH----------YHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDED 262
+LL + H YHV HIS + ++ VR+ +K + +TCEVTPHH +E
Sbjct: 222 LLLIDYLRKHKLSPPLTAPRYHVAHISTRSALDLVRKARKEGMAITCEVTPHHFTLTEEA 281
Query: 263 I--KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGI 320
+ E G + M PPL ++ A++ ++DGTID IATDHAPH EK +++SFGI
Sbjct: 282 LFKAEHKGNFIMKPPLCSLDNHAAILEAIVDGTIDAIATDHAPHAEHEKQCPPDQASFGI 341
Query: 321 VGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKE 380
+G ETA +++ V T S+ ++++S N +I ++ E A+ +ID +
Sbjct: 342 IGLETAVGLTFSELVHTGRISVSRAIEMLSVNPRRIMDIEPVLFEPQRAANFTLIDPDAT 401
Query: 381 ITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
T E SK +N+P+ + G + GK+ +D
Sbjct: 402 WTWKSEHIKSKAKNSPFIGRTMKGKAIGICHKGKLLGLD 440
>gi|145594397|ref|YP_001158694.1| dihydroorotase, multifunctional complex type [Salinispora tropica
CNB-440]
gi|145303734|gb|ABP54316.1| dihydroorotase, multifunctional complex type [Salinispora tropica
CNB-440]
Length = 425
Score = 241 bits (616), Expect = 5e-62, Method: Composition-based stats.
Identities = 141/413 (34%), Positives = 212/413 (51%), Gaps = 13/413 (3%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
D+LI+D + + + +D +D G +D H H REPG ETV T SRAA
Sbjct: 18 DLLIRDGVVAETGVGLTASDAVVVDGTGLVALPGLVDLHTHLREPGREDAETVATGSRAA 77
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR---ELSDM 134
A GGFT V M N +PV D+ + + + + ++ P GA+T G+ EL M
Sbjct: 78 ALGGFTAVCAMANTSPVADTAGVVEQVWRLGREAGLVDVQPIGAVTVGLAGQRLAELGAM 137
Query: 135 EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAE 194
D A +V F+DDG V +M A+ + + H E+ L G MHEG+ S
Sbjct: 138 ADSAARVRIFSDDGHCVADPRLMRRALEYVKAFDGIVAQHAEEPRLTEGAQMHEGEISTR 197
Query: 195 LGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPH 254
LG+ G P++ E IARD+LLAE H+CH+S SV +R+ K ++VT EVTPH
Sbjct: 198 LGLTGWPAVAEEAIIARDVLLAEHVGSRLHICHVSTAGSVGVLRQAKARGVQVTAEVTPH 257
Query: 255 HLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIE 314
HLL DE + ++K+NPPLR D AL + +G +DI+ATDHAPH++E+K
Sbjct: 258 HLLLTDEKAVTYDPVYKVNPPLRTAADVAALRTALAEGVVDIVATDHAPHSVEDKECEWA 317
Query: 315 KSSFGIVGSETAFTQLYTKFVKTDIFS--LEMLVKLMSENVAKIFNLPYGKLE--ENSFA 370
+ G++G ETA + + D+ +++ + MS A+I L + + A
Sbjct: 318 YARPGMLGLETALS------ITLDVLGPRWDLIAERMSRTPARIAGLTEHGHDPAPGAPA 371
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKEEI 423
++ ++D + P E S+ RNTPYA + G V T G+ +D + +
Sbjct: 372 NLTLVDPAARRVVEPTELASRSRNTPYARMTLPGRIVATFLRGEATVLDGKAV 424
>gi|119716656|ref|YP_923621.1| dihydroorotase, multifunctional complex type [Nocardioides sp.
JS614]
gi|119537317|gb|ABL81934.1| dihydroorotase, multifunctional complex type [Nocardioides sp.
JS614]
Length = 432
Score = 240 bits (612), Expect = 1e-61, Method: Composition-based stats.
Identities = 154/429 (35%), Positives = 214/429 (49%), Gaps = 17/429 (3%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
L+KN +L D+L++D I E D D ID G +D H H RE
Sbjct: 6 LIKNVSVLGG---TPTDLLLEDGVIR---EAADRPDAEVIDATGLIALPGLVDLHTHLRE 59
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG ETV T + AAA GGFT V M N PV D+ + + + + P GA
Sbjct: 60 PGREDAETVETGTHAAAMGGFTAVHAMANTEPVADTAGVVEQVWRLGREAGYCDVFPVGA 119
Query: 122 IT---KEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+T + E EL M D A +V F+DDG+ V A +M A+ + + H ++
Sbjct: 120 VTVGLQGERLAELGAMADSAARVRVFSDDGKCVSDAVLMRRALEYVKAFDGVVAQHAQEP 179
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
L G M+EG+ S LG+ G P++ E IARD+LLAE HVCH+S SV +R
Sbjct: 180 RLTEGAQMNEGELSGRLGLAGWPAVAEEAIIARDLLLAEHVGSRLHVCHVSTAGSVELIR 239
Query: 239 EGKKN-----NIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGT 293
K + VT E PHHLL DE + ++K+NPPLR D AL AG+ DGT
Sbjct: 240 WAKAKAEKDGHWEVTAEACPHHLLLTDELAATYDPIYKVNPPLRTAADAQALRAGLADGT 299
Query: 294 IDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENV 353
IDI+ATDHAPH E+K ++FG++G ETA + + V T + L + MS
Sbjct: 300 IDIVATDHAPHPHEDKDCEWAAAAFGMLGLETALSVVQQTMVDTGLLDWAGLAERMSYAP 359
Query: 354 AKIFNLP--YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTI 410
A+I + +G+ + A++V+ D TI+P E S RNTPY ++ G V T
Sbjct: 360 ARIGRVSDQHGRPVAIGEPANMVLYDPGATRTIDPSESASLSRNTPYRGMELPGRVVATF 419
Query: 411 SNGKIAYID 419
G+ +D
Sbjct: 420 LRGRATVLD 428
>gi|15827190|ref|NP_301453.1| dihydroorotase [Mycobacterium leprae TN]
gi|21542206|sp|Q9CCR4|PYRC_MYCLE Dihydroorotase (DHOase)
gi|13092738|emb|CAC30041.1| putative dihydroorotase [Mycobacterium leprae]
Length = 430
Score = 240 bits (612), Expect = 1e-61, Method: Composition-based stats.
Identities = 146/421 (34%), Positives = 218/421 (51%), Gaps = 8/421 (1%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHW 59
+LL+ ++ G+ +VD+L++ ++I I ID+ D + ID D+ + G +D H H
Sbjct: 3 VLLRGVRLYGEGE--QVDVLVEGEQIANIGAGIDIPDTADVIDAIDQVLLPGLVDLHTHL 60
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG E + T S AAA GG+T V MPN PV DS + + ++ P
Sbjct: 61 REPGREYAEDIETGSAAAALGGYTAVFAMPNTTPVADSPVVTDHVWRRGQQVGLVDVHPV 120
Query: 120 GAITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
GA+T G EL++M +A +V F+DDG V + VM A+ + L I H E
Sbjct: 121 GAVTVGLAGAELTEMGMMAAGAAQVRIFSDDGNCVHNPLVMRRALEYATGLGVLIAQHAE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
+ L G HEG +A LG+ G P E + +ARD LLA A H+CH S +V
Sbjct: 181 EPRLTVGAVAHEGPTAARLGLSGWPRAAEESIVARDALLARDAGARVHICHASTAGTVEI 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
++ K+ I +T EVTPHHLL D + +G+ ++NPPLR D AL + DG ID
Sbjct: 241 LKWAKEQGISITAEVTPHHLLLDDSRLASYDGVNRVNPPLRETADAVALRQALADGIIDC 300
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
+ TDHAPH EK + G++G +TA + + V + S + ++MSEN A+I
Sbjct: 301 VTTDHAPHADHEKCVEFSAARPGMLGLQTALSVVVHTMVVPGLLSWRDVAQVMSENPARI 360
Query: 357 FNLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
LP +G+ LE A++ V+D + T+ + S+ NTPY + T+ GK
Sbjct: 361 AGLPDHGRPLEVGEPANLTVVDPDVTWTVTGDGLASRSANTPYEAMTLPATVTATLLRGK 420
Query: 415 I 415
+
Sbjct: 421 V 421
>gi|116670812|ref|YP_831745.1| dihydroorotase, multifunctional complex type [Arthrobacter sp.
FB24]
gi|116610921|gb|ABK03645.1| dihydroorotase, multifunctional complex type [Arthrobacter sp.
FB24]
Length = 462
Score = 239 bits (611), Expect = 2e-61, Method: Composition-based stats.
Identities = 142/413 (34%), Positives = 214/413 (51%), Gaps = 9/413 (2%)
Query: 18 DILIKDDKIEKISENIDVTDE----NTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
D+LI+D I ++ TD I+ G +D H H REPG ETV T
Sbjct: 28 DLLIRDGIIAARGTDLAGTDAADGATVIEAAGLVALPGMVDIHTHLREPGREDAETVETG 87
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSD 133
+RAAA GG+T V M N NPV D+ + + + + + P GA+T G +L++
Sbjct: 88 TRAAALGGYTAVHAMANSNPVADTAGVVEQVHTLGRAAGWVDVRPVGAVTVGLAGEQLAE 147
Query: 134 MEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGK 190
+ +AD KV F+DDG V +M A+ + + H ++ L G M+EG
Sbjct: 148 LGAMADSRAKVRVFSDDGICVHDPVIMRRALEYVKAFDGVVAQHAQEPRLTAGAQMNEGD 207
Query: 191 RSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
SA LG+ G P++ E + IARD+LLA+ HVCH+S SV +R K I VT E
Sbjct: 208 VSAVLGLTGWPAVAEESIIARDVLLAQHVGSRLHVCHVSTAGSVEIIRWAKARGINVTAE 267
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
VTPHHLL DE ++ + ++K+NPPLR D AL A + DGTID++ TDHAPH E K
Sbjct: 268 VTPHHLLLTDELVRSYDPVYKVNPPLRTDSDVQALRAALADGTIDVVGTDHAPHPSEHKE 327
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LEENS 368
+++ G+ G ETA + + ++T + ++ S A I + G+ LE
Sbjct: 328 CEWAQAAMGMTGLETALSVVQETMIETGLMGWADFARVTSTAPAVIGRVADQGRPLEAGE 387
Query: 369 FADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKE 421
A++ ++D T++P + + GRN+P+A ++ G V T G ++ E
Sbjct: 388 PANVTLVDPAARWTVDPSKMATMGRNSPFAGRELPGKVVATFFKGHPTVLNGE 440
>gi|156742404|ref|YP_001432533.1| dihydroorotase, multifunctional complex type [Roseiflexus
castenholzii DSM 13941]
gi|156233732|gb|ABU58515.1| dihydroorotase, multifunctional complex type [Roseiflexus
castenholzii DSM 13941]
Length = 497
Score = 239 bits (610), Expect = 2e-61, Method: Composition-based stats.
Identities = 156/449 (34%), Positives = 224/449 (49%), Gaps = 50/449 (11%)
Query: 18 DILIKDDKIEKISENIDVT------DENT--IDVKDRFVTAGFIDAHVHWREPGFSKKET 69
++L+++ K+ ++ + D+T D++T I+ + + GF+D H H REPG KET
Sbjct: 22 NVLVENGKVIQVIDLADLTVAPEPLDDHTEVINARGAVIAPGFLDLHAHVREPGEEHKET 81
Query: 70 VYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR 129
V TA++AAA GGFTT+ MP+ P D + EI + ++R P GAIT G+
Sbjct: 82 VETATKAAAAGGFTTLCVMPDTRPAIDCAAVARQVREIARRRGLVRIEPIGAITLGRAGQ 141
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
L++M ++ + F+D+G V A VM A+ + L+ I+AHCED L R MHE
Sbjct: 142 TLTEMAELVEAGCVGFSDEGNAVADAAVMRNALAYAAMLDVPIMAHCEDVRLTRNWGMHE 201
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G S LG+ G P+ E +ARDI LAE H H+CH+S SV +R K +RVT
Sbjct: 202 GAVSIRLGLPGYPAAAEEVMVARDIALAEMTGAHLHICHVSTAGSVALIRAAKARGVRVT 261
Query: 249 CEVTPHHLLSCDEDI-----------------------KEDNGM---------------- 269
EVTPHHL D+ + D+G+
Sbjct: 262 AEVTPHHLTLTDQWVLGNLAAVRGGAKAGQRSSREQSEMSDDGLDLPSRLKPTLLPPYHT 321
Query: 270 -WKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFT 328
++ PPLR +D ALI G+ DG ID IA+DH P + EK ++ GI ETA
Sbjct: 322 STRVRPPLRTEQDIEALIEGLRDGAIDAIASDHEPQSAVEKACEYRLAAPGISSLETALG 381
Query: 329 QLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEF 388
L V L LV +E A + L S ADIV+ D + T+ PE+F
Sbjct: 382 -LALTLVHRGKLDLVDLVAKFTEGPATVLGRAPATLRPGSPADIVIFDPDSPWTVEPEKF 440
Query: 389 LSKGRNTPYANEKVNGIPVLTISNGKIAY 417
SKGRNTP +++ G +LT+ G+I +
Sbjct: 441 FSKGRNTPLVGQRLKGQVMLTMCRGQIVF 469
>gi|41407214|ref|NP_960050.1| dihydroorotase [Mycobacterium avium subsp. paratuberculosis K-10]
gi|41395565|gb|AAS03433.1| PyrC [Mycobacterium avium subsp. paratuberculosis K-10]
Length = 430
Score = 239 bits (610), Expect = 3e-61, Method: Composition-based stats.
Identities = 149/425 (35%), Positives = 219/425 (51%), Gaps = 8/425 (1%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHW 59
+LL+ ++ G +VD+L+ D +I I +D+ D + ID + + GF+D H H
Sbjct: 3 VLLRGVRLYGEGD--RVDVLVDDGQIADIGAGLDIPDTADVIDATGQVLLPGFVDLHTHL 60
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG E + T S AAA GG+T V M N NPV DS + + ++ P
Sbjct: 61 REPGREYAEDIETGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPV 120
Query: 120 GAITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
GA+T G+EL++M +A +V F+DDG V VM A+ + L I H E
Sbjct: 121 GAVTMGLAGKELTEMGMMAAGAAQVRMFSDDGVCVHDPLVMRRALEYATGLGVLIAQHAE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
+ L G HEG +A LG+ G P E + +ARD LLA A H+CH S +V
Sbjct: 181 EPRLTVGAVAHEGPTAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTAGTVEI 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
V+ K+ I +T EVTPHHL+ D + +G ++NPPLR D AL + DG ID
Sbjct: 241 VKWAKQQGISITAEVTPHHLMLDDSRLASYDGRNRVNPPLREAADAAALRRALADGVIDC 300
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
+ATDHAPH EK + G++G +TA + + V+ + + + K+MSEN A+I
Sbjct: 301 VATDHAPHAEHEKCVEFSAARPGMLGLQTALSIVVHTMVRPGLLTWRDIAKVMSENPARI 360
Query: 357 FNLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
NLP +G+ LE A++ V+D + T+ + S+ NTPY + T+ GK
Sbjct: 361 ANLPDHGRPLEVGEPANLTVVDPDASWTVAGSDLASRSANTPYEAMTLPATVTATLLRGK 420
Query: 415 IAYID 419
+ D
Sbjct: 421 VTARD 425
>gi|145224328|ref|YP_001135006.1| dihydroorotase, multifunctional complex type [Mycobacterium gilvum
PYR-GCK]
gi|145216814|gb|ABP46218.1| dihydroorotase, multifunctional complex type [Mycobacterium gilvum
PYR-GCK]
Length = 427
Score = 239 bits (609), Expect = 3e-61, Method: Composition-based stats.
Identities = 147/424 (34%), Positives = 221/424 (52%), Gaps = 9/424 (2%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
++LK+ ++ G VD+L++D I +I + + + TID R + GF+D H H R
Sbjct: 3 VVLKSVRLYGEGD--AVDVLVRDGIIAEIGTGL--SADETIDCTGRVLLPGFVDLHTHLR 58
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
EPG E + T S AAA GG+T V M N +PV DSV + + + ++ P G
Sbjct: 59 EPGREYAEDIETGSAAAALGGYTAVFAMANTDPVADSVVVTDHVWQRGQQVGLVDVHPVG 118
Query: 121 AITKEEYGRELSDMEDIA---DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
A+T G++L++M +A +V F+DDG V +M A+ S L I H E+
Sbjct: 119 AVTVGLAGKQLTEMGLMAAGTGRVRMFSDDGVCVDDPLLMRRALEYASGLGVLIAQHAEE 178
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L G HEG +A LG+ G P E + +ARD LLA A H+CH S +V V
Sbjct: 179 PRLTVGAVAHEGPNAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTAGTVELV 238
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
R K+ I +T EVTPHHLL D ++ +G ++NPPLR D AL + DG ID +
Sbjct: 239 RWAKEQGIAITAEVTPHHLLLDDTRLETYDGRNRVNPPLREVSDTLALRQALADGVIDCV 298
Query: 298 ATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
ATDHAPH EK+ + G++G +TA + + V+ + + ++MSE A+I
Sbjct: 299 ATDHAPHGEHEKMCEFANARPGMLGLQTALSVVVETMVQPGPLTWRDVARVMSEAPARIV 358
Query: 358 NLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
LP G+ LE A++ V+D + T++ S+ NTPY ++ G+ T+ G +
Sbjct: 359 GLPDQGRPLEVGEPANLTVVDPDARWTVSGPALASRSDNTPYEAMELPGVVTATLLRGTV 418
Query: 416 AYID 419
D
Sbjct: 419 TARD 422
>gi|118464737|ref|YP_882574.1| dihydroorotase [Mycobacterium avium 104]
gi|118166024|gb|ABK66921.1| dihydroorotase [Mycobacterium avium 104]
Length = 430
Score = 239 bits (609), Expect = 3e-61, Method: Composition-based stats.
Identities = 149/425 (35%), Positives = 219/425 (51%), Gaps = 8/425 (1%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHW 59
+LL+ ++ G +VD+L+ D +I I +D+ D + ID + + GF+D H H
Sbjct: 3 VLLRGVRLYGEGD--RVDVLVDDGQIADIGAGLDIPDTADVIDATGQVLLPGFVDLHTHL 60
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG E + T S AAA GG+T V M N NPV DS + + ++ P
Sbjct: 61 REPGREYAEDIETGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPV 120
Query: 120 GAITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
GA+T G+EL++M +A +V F+DDG V VM A+ + L I H E
Sbjct: 121 GAVTMGLAGKELTEMGMMAAGAAQVRMFSDDGVCVHDPLVMRRALEYATGLGVLIAQHAE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
+ L G HEG +A LG+ G P E + +ARD LLA A H+CH S +V
Sbjct: 181 EPRLTVGAVAHEGPTAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTAGTVEI 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
V+ K+ I +T EVTPHHL+ D + +G ++NPPLR D AL + DG ID
Sbjct: 241 VKWAKQQGISITAEVTPHHLMLDDSRLASYDGRNRVNPPLREAADAAALRRALADGVIDC 300
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
+ATDHAPH EK + G++G +TA + + V+ + + + K+MSEN A+I
Sbjct: 301 VATDHAPHAEHEKCVEFSAARPGMLGLQTALSIVVHTMVRPGLLTWRDVAKVMSENPARI 360
Query: 357 FNLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
NLP +G+ LE A++ V+D + T+ + S+ NTPY + T+ GK
Sbjct: 361 ANLPDHGRPLEVGEPANLTVVDPDASWTVAGSDLASRSANTPYEAMTLPATVTATLLRGK 420
Query: 415 IAYID 419
+ D
Sbjct: 421 VTARD 425
>gi|148272967|ref|YP_001222528.1| putative dihydroorotase [Clavibacter michiganensis subsp.
michiganensis NCPPB 382]
gi|147830897|emb|CAN01841.1| putative dihydroorotase [Clavibacter michiganensis subsp.
michiganensis NCPPB 382]
Length = 470
Score = 238 bits (608), Expect = 5e-61, Method: Composition-based stats.
Identities = 144/416 (34%), Positives = 210/416 (50%), Gaps = 16/416 (3%)
Query: 15 KKVDILIKDDKIEKISENIDV-TDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
++ DIL+ D I +I ++ + I+ G +D HVH REPG+ + ETV T
Sbjct: 23 ERADILVADGLIREIGPGLETPAGAHVIEADGLVALPGLVDLHVHLREPGYEQSETVLTG 82
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSD 133
SRAAA GGFT V M N PV D+ + + + P GA++ G +++
Sbjct: 83 SRAAALGGFTAVFAMANTMPVQDTAGVVEQVKALGDAAGYATVRPIGAVSVGLAGESMAE 142
Query: 134 MEDIADK---VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGK 190
+ +A V F+DDG+ V +M A+ + I H +D L G M+EG
Sbjct: 143 IGAMASSRAAVRVFSDDGKCVADPLLMRRALEYVKAFDGVIAQHAQDPRLTEGATMNEGA 202
Query: 191 RSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCE 250
S ELGI G P++ E + IARD+LLAE HVCH+S SV +R K + VT E
Sbjct: 203 LSGELGITGWPAVAEESIIARDVLLAEHVGSRLHVCHVSTAGSVDVIRWAKARGVDVTAE 262
Query: 251 VTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKI 310
VTPHHLL ++ + + +K+NPPLR RED AL + DGTID++ATDHAPH E K
Sbjct: 263 VTPHHLLLTEDLVAGYDARYKVNPPLRRREDVEALRQALADGTIDVVATDHAPHPTEAKD 322
Query: 311 RGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEEN--- 367
+ ++FG+VG E+A + + V T + + ++MS A+I G+L E+
Sbjct: 323 CEWDAAAFGMVGLESALSVVQLAMVDTGLLDWAGVARVMSHAPARI-----GRLAEHGHA 377
Query: 368 ----SFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
S ADI + D + ++ N+PY + G V T G +D
Sbjct: 378 LAGGSPADITLYDPSASRVFDRDDLGGLSGNSPYLEMTLPGRVVATFHRGYPTVLD 433
>gi|68536101|ref|YP_250806.1| dihydroorotase [Corynebacterium jeikeium K411]
gi|68263700|emb|CAI37188.1| dihydroorotase [Corynebacterium jeikeium K411]
Length = 466
Score = 238 bits (607), Expect = 5e-61, Method: Composition-based stats.
Identities = 144/418 (34%), Positives = 228/418 (54%), Gaps = 12/418 (2%)
Query: 8 ILKNGKFKKVDILIKDDKIEKISENIDVTDE-----NTIDVKDRFVTAGFIDAHVHWREP 62
+L G+ +K D+LI+D I +I D+ D +D+ + + G +D HVH REP
Sbjct: 42 VLLYGEGEKQDVLIQDGVIAEIGA--DLADSAPQGAEVLDLDGQVLLPGLVDMHVHLREP 99
Query: 63 GFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAI 122
G ET+ T S AAA+GGFT V TM N PV D+ +N ++ P G+I
Sbjct: 100 GREDTETIATGSAAAAQGGFTAVFTMANTAPVTDNPAIAEMVWFKGQNTNLCDVHPVGSI 159
Query: 123 TKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNS 179
+K G+EL++ +AD KV F+DDG+ V +M A+ ++ + HCE+
Sbjct: 160 SKGLEGKELTEFGMMADSDAKVRMFSDDGKCVDDPRLMRRAIEYSKGMDVLLAQHCEEPR 219
Query: 180 LIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVRE 239
L G HEG+ +A LG+ G P + E + +ARD ++A H+CH S + +V +R
Sbjct: 220 LTEGAVAHEGETAARLGLGGWPRVAEESIVARDAIMARDYGGRLHICHASTEGTVELLRW 279
Query: 240 GKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIAT 299
K +I ++ EVTPHHLL D ++ +G+ ++NPPLR + D AL A ++DGT+D +AT
Sbjct: 280 VKDQDIPLSAEVTPHHLLLTDARLETYDGVNRVNPPLREQRDVEALRAALIDGTVDCVAT 339
Query: 300 DHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL 359
DHAPH E+K +++ G++G ET+ + FV + K+MSE A+I L
Sbjct: 340 DHAPHGSEDKCCEFDQARPGMLGIETSLALIAKIFVIDGDEDWRFVAKVMSERPAEITKL 399
Query: 360 P-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
P +G+ + A++ +DL ++ T + ++ SK NTPY ++ T+ GK+
Sbjct: 400 PGHGRPIAVGEPANLCAVDLNQKWTAHGKDMASKANNTPYEGMEMPVKVTTTLLRGKV 457
>gi|118617397|ref|YP_905729.1| dihydroorotase PyrC [Mycobacterium ulcerans Agy99]
gi|118569507|gb|ABL04258.1| dihydroorotase PyrC [Mycobacterium ulcerans Agy99]
Length = 430
Score = 238 bits (607), Expect = 6e-61, Method: Composition-based stats.
Identities = 146/425 (34%), Positives = 217/425 (51%), Gaps = 8/425 (1%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHW 59
+LL+ ++ G+ +VD+L+ D++I I + + D + ID D + G +D H H
Sbjct: 3 VLLRGVRLYGEGE--RVDVLVDDNQIADIGTGLAIPDTADVIDATDHVLLPGLVDLHTHL 60
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG E + T S AAA GG+T V M N +PV DS + + ++ P
Sbjct: 61 REPGREYAEDIETGSAAAALGGYTAVFAMANTHPVADSPVVTDHVWHRGQQVGLVDVHPV 120
Query: 120 GAITKEEYGRELSDMEDIADKVFA---FTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
GA+T G EL++M + V A F+DDG V +M A+ + L I H E
Sbjct: 121 GAVTIGLAGTELTEMGMMNAGVAAVRMFSDDGICVHDPLIMRRALEYATGLGVLIAQHAE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
+ L G HEG +A+LG+ G P E + +ARD LL A H+CH S +V
Sbjct: 181 EPRLTVGAVAHEGPSAAQLGLAGWPRAAEESIVARDALLTRDAGARVHICHASTVGTVEI 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
++ K I +T EVTPHHLL D + +G+ ++NPPLR D AL + DG ID
Sbjct: 241 LKWAKSQGISITAEVTPHHLLLDDRRLSGYDGVNRVNPPLREASDAMALRQALADGIIDC 300
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
+ATDHAPH EK + G++G +TA + + V+ + S + ++MSEN A+I
Sbjct: 301 VATDHAPHAEHEKCVEFSAARPGMLGLQTALSVVVQTMVQPGLLSWRDVARVMSENPARI 360
Query: 357 FNLP-YGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
LP +G+ LE A++ VID + T+ + S+ NTPY + + T+ GK
Sbjct: 361 VGLPDHGRPLEVGEPANLTVIDPDATWTVTGADLASRSANTPYESMTLPARVTATLLRGK 420
Query: 415 IAYID 419
I D
Sbjct: 421 ITARD 425
>gi|110800858|ref|YP_695831.1| dihydroorotase, multifunctional complex type [Clostridium
perfringens ATCC 13124]
gi|110675505|gb|ABG84492.1| dihydroorotase, multifunctional complex type [Clostridium
perfringens ATCC 13124]
Length = 399
Score = 238 bits (606), Expect = 7e-61, Method: Composition-based stats.
Identities = 150/419 (35%), Positives = 227/419 (54%), Gaps = 28/419 (6%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN ++ DI I+ I+++ ++ E T+D K + FID H H+R
Sbjct: 3 LLIKNVNLIDESNNFFGDIYIEKGVIKELGTELNKECE-TLDGKGLVLMPAFIDTHAHFR 61
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
+PGF KE + + S+AA RGG+TTV MPN PV S E L+ + K ++
Sbjct: 62 DPGFEYKEDIESGSKAAVRGGYTTVTLMPNTKPVCSSKEILDYVVNKGKEVGLVDLYQTV 121
Query: 121 AITKEEYGRELSDMEDIADK--VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+ITK G E++ + + V A TDDG+GV + +M EAM + + N +++H E
Sbjct: 122 SITKNLSGEEINHLREFEGNPNVKAITDDGKGVSDSKIMMEAMKIAKENNWIVMSHAE-- 179
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
S E K + E+ RDI LA+ +C H+ H+S KE+++ +
Sbjct: 180 -------------SPEFS-KVDMRLAENMMTWRDITLAKFVDCRLHMSHVSTKEAMKYII 225
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
EGK + ++VTCE+TPHHL + +++NPP+R ED N LI + + I
Sbjct: 226 EGKNDGVKVTCEITPHHLA-----LNNKISNYRVNPPIREEEDVNFLIKAIKMNYVYCIG 280
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH+ E+K EK + G++G E AF+ YTK VK + SL L +LMS N AK+ N
Sbjct: 281 TDHAPHSKEDK----EKGAPGMIGIEQAFSICYTKLVKENHISLNKLSQLMSGNAAKLLN 336
Query: 359 LPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+ GKL+ D+V+IDL K+ E+ +S+ +NTP+ + G V+TI NGKI Y
Sbjct: 337 INKGKLQPGFLGDLVLIDLNKKRIFKEEDIVSRSKNTPFNGMEFYGDVVVTIKNGKIVY 395
>gi|84496658|ref|ZP_00995512.1| dihydroorotase [Janibacter sp. HTCC2649]
gi|84383426|gb|EAP99307.1| dihydroorotase [Janibacter sp. HTCC2649]
Length = 430
Score = 238 bits (606), Expect = 7e-61, Method: Composition-based stats.
Identities = 147/405 (36%), Positives = 212/405 (52%), Gaps = 7/405 (1%)
Query: 18 DILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
D+L+ + +I I +DV TID + GF+D H H REPG ET+ + + A
Sbjct: 18 DVLVLEGQIAAIGTGLDVPQGVETIDADGLALLPGFVDLHTHLREPGREDAETIESGAAA 77
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSD--- 133
AA GG+T V+ M N NPV D+ E + L++ + ++ P GA+TK G EL++
Sbjct: 78 AAVGGYTAVLAMANTNPVTDTAEAAERILDLGRATWLVEVQPIGAVTKGLAGEELAELAL 137
Query: 134 MEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAM-HEGKRS 192
M V F+DDGR V A VM A+ + H +D L A HEG+ S
Sbjct: 138 MHRSRANVRVFSDDGRCVHDARVMRRALEYVRAFGGVVSQHSQDPDLAGSSACCHEGELS 197
Query: 193 AELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVT 252
LG+ G P++ ES+ IARD LA+ N HV H++ E V VR K I +T EVT
Sbjct: 198 GRLGLPGWPAVAESSIIARDAQLAQHTNSRVHVAHVTTAEGVEVVRWAKARGIDLTAEVT 257
Query: 253 PHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRG 312
PHHLL ++ + + +K+NPPLR ED AL + DGTID +ATDHAPH +K
Sbjct: 258 PHHLLLTEDLVSGYDPTFKVNPPLRPIEDVEALRTALADGTIDAVATDHAPHARHDKEHA 317
Query: 313 IEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL-PYGK-LEENSFA 370
++FG++G ETAF ++ V+ L L MS A+I L +G+ +E + A
Sbjct: 318 FVDAAFGMLGLETAFAVVHDTMVRNGALDLAGLADRMSTAPARIAGLGDHGRAIEVGAPA 377
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
++V++D E T++ S RN P+ G TI G++
Sbjct: 378 NLVLVDTEANQTVDASASKSLSRNNPWHGMSFTGAVHTTILRGRV 422
>gi|15608521|ref|NP_215897.1| dihydroorotase [Mycobacterium tuberculosis H37Rv]
gi|15840839|ref|NP_335876.1| dihydroorotase [Mycobacterium tuberculosis CDC1551]
gi|81254662|ref|ZP_00879174.1| COG0044: Dihydroorotase and related cyclic amidohydrolases
[Mycobacterium tuberculosis C]
gi|148661172|ref|YP_001282695.1| dihydroorotase [Mycobacterium tuberculosis H37Ra]
gi|148822601|ref|YP_001287355.1| dihydroorotase pyrC [Mycobacterium tuberculosis F11]
gi|9087175|sp|P71809|PYRC_MYCTU Dihydroorotase (DHOase)
gi|1621263|emb|CAB02642.1| PROBABLE DIHYDROOROTASE PYRC (DHOase) [Mycobacterium tuberculosis
H37Rv]
gi|13881037|gb|AAK45690.1| dihydroorotase [Mycobacterium tuberculosis CDC1551]
gi|124600688|gb|EAY59698.1| dihydroorotase pyrC [Mycobacterium tuberculosis C]
gi|134149784|gb|EBA41829.1| dihydroorotase pyrC [Mycobacterium tuberculosis str. Haarlem]
gi|148505324|gb|ABQ73133.1| dihydroorotase [Mycobacterium tuberculosis H37Ra]
gi|148721128|gb|ABR05753.1| dihydroorotase pyrC [Mycobacterium tuberculosis F11]
Length = 430
Score = 238 bits (606), Expect = 7e-61, Method: Composition-based stats.
Identities = 144/414 (34%), Positives = 212/414 (51%), Gaps = 6/414 (1%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
G+ ++VD+L+ D +I +I ++ + D + ID + GF+D H H REPG E +
Sbjct: 12 GEGERVDVLVDDGQIAQIGPDLAIPDTADVIDATGHVLLPGFVDLHTHLREPGREYAEDI 71
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRE 130
T S AAA GG+T V M N NPV DS + + ++ P GA+T G E
Sbjct: 72 ETGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGAE 131
Query: 131 LSDMEDI---ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
L++M + A +V F+DDG V +M A+ + L I H E+ L G H
Sbjct: 132 LTEMGMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLTVGAVAH 191
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
EG +A LG+ G P E + +ARD LLA A H+CH SA +V ++ K I +
Sbjct: 192 EGPMAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASAAGTVEILKWAKDQGISI 251
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
T EVTPHHLL D + +G+ ++NPPLR D AL + DG ID +ATDHAPH
Sbjct: 252 TAEVTPHHLLLDDARLASYDGVNRVNPPLREASDAVALRQALADGIIDCVATDHAPHAEH 311
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LE 365
EK + G++G +TA + + V + S + ++MSEN A I LP G+ LE
Sbjct: 312 EKCVEFAAARPGMLGLQTALSVVVQTMVAPGLLSWRDIARVMSENPACIARLPDQGRPLE 371
Query: 366 ENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
A++ V+D + T+ + S+ NTP+ + + T+ GK+ D
Sbjct: 372 VGEPANLTVVDPDATWTVTGADLASRSANTPFESMSLPATVTATLLRGKVTARD 425
>gi|94987261|ref|YP_595194.1| Dihydroorotase and related cyclic amidohydrolases [Lawsonia
intracellularis PHE/MN1-00]
gi|94731510|emb|CAJ54873.1| Dihydroorotase and related cyclic amidohydrolases [Lawsonia
intracellularis PHE/MN1-00]
Length = 423
Score = 238 bits (606), Expect = 7e-61, Method: Composition-based stats.
Identities = 149/409 (36%), Positives = 212/409 (51%), Gaps = 13/409 (3%)
Query: 15 KKVDILIKDDKIEKISENIDVT-----DENTIDVKDRFVTAGFIDAHVHWREPGFSKKET 69
K V + ++D KI + E + D + +D K + + FID H H REPG+ KET
Sbjct: 14 KLVSLEVRDGKIITLKEGEQNSTSSPIDLHPVDAKQKHLFPSFIDVHTHLREPGYEWKET 73
Query: 70 VYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIK----NDSVIRAIPYGAITKE 125
+ T AAA GGF +V+ M N NPV DS K LE K N + P GA T
Sbjct: 74 IATGLAAAAHGGFGSVLCMANTNPVNDSATVTCKILESGKYAFPNGPYV--YPIGAATIG 131
Query: 126 EYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGG 184
G +LS M ++A+ A ++DG +++ + + S L ++ HCED L
Sbjct: 132 LKGEQLSPMHELAEAGCIAISNDGLPIKNTELFRRILEYASDLGLIVIDHCEDPYLACDT 191
Query: 185 AMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNN 244
M+EG S +LG+ G P I E+ Q R ILLAE N H+ H+SAK +V A+ GK
Sbjct: 192 HMNEGFISGKLGLSGQPDIAETLQAIRSILLAEYLNVPVHIAHVSAKRTVEAISWGKSRG 251
Query: 245 IRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPH 304
++VT E PH+LL + + N K+NPPLR +ED AL + G ID++ATDHAPH
Sbjct: 252 VKVTAETCPHYLLLDERAVIGYNTNAKVNPPLRTQEDIMALREAIKTGIIDMLATDHAPH 311
Query: 305 TMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKL 364
EK +K+ G G + A +Y+ V+ + S L++L S N A +FNLP
Sbjct: 312 AAYEKEVPFDKAPNGFTGFDVAIPVMYS-LVREGVLSESDLIRLWSNNPAGVFNLPINNF 370
Query: 365 EENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
+ A+ + D E E T++ E SK NTP+ E + G V+ NG
Sbjct: 371 KPGDPANFFLFDPELEWTVSKENLYSKSWNTPWLGETLKGRVVMHWING 419
>gi|119883927|ref|ZP_01650175.1| dihydroorotase, multifunctional complex type [Salinispora arenicola
CNS205]
gi|119823287|gb|EAX25856.1| dihydroorotase, multifunctional complex type [Salinispora arenicola
CNS205]
Length = 425
Score = 237 bits (605), Expect = 9e-61, Method: Composition-based stats.
Identities = 141/413 (34%), Positives = 209/413 (50%), Gaps = 13/413 (3%)
Query: 18 DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAA 77
D+LI+D + + + D ++ G +D H H REPG ETV T SRAA
Sbjct: 18 DLLIRDGVVAEAGTGLAAPDAVVVNGTGLVALPGLVDLHTHLREPGREDAETVETGSRAA 77
Query: 78 ARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR---ELSDM 134
A GG+T V M N +PV D+ + + + + ++ P GA+T G EL M
Sbjct: 78 ALGGYTAVCAMANTSPVADTAGVVEQVWRLGREAGLVDVQPIGAVTVGLAGERLAELGAM 137
Query: 135 EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAE 194
D A +V F+DDG V +M A+ + + H E+ L G MHEG+ +
Sbjct: 138 ADSAARVRVFSDDGHCVADPRLMRRALEYVKAFDGIVAQHAEEPRLTEGAQMHEGEVATR 197
Query: 195 LGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPH 254
LG+ G P++ E IARD+LLAE HVCH+S SV +R+ K ++VT EVTPH
Sbjct: 198 LGLTGWPAVAEEAIIARDVLLAEHVGSRLHVCHVSTAGSVGVLRQAKARGVQVTAEVTPH 257
Query: 255 HLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIE 314
HLL DE + ++K+NPPLR D AL + +G IDI+ATDHAPH +E+K
Sbjct: 258 HLLLTDEKAATYDPVYKVNPPLRTAADIAALRTALAEGIIDIVATDHAPHAVEDKECEWA 317
Query: 315 KSSFGIVGSETAFTQLYTKFVKTDIF--SLEMLVKLMSENVAKIFNLPYGKLE--ENSFA 370
+ G++G ETA + + D+ +++ + MS A+I L + + A
Sbjct: 318 YARPGMLGLETALS------IALDVLGPQWDLIAERMSRAPARIAGLAEHGHDPAPGAPA 371
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKEEI 423
++ ++D T+ P E S+ RNTPYA + G V T G +D + +
Sbjct: 372 NLTLVDPAARRTVEPTELASRSRNTPYARMTLPGRIVATFLRGVATVLDGKAV 424
>gi|31792575|ref|NP_855068.1| dihydroorotase [Mycobacterium bovis AF2122/97]
gi|121637311|ref|YP_977534.1| putative dihydroorotase pyrC [Mycobacterium bovis BCG str. Pasteur
1173P2]
gi|59798370|sp|Q7U057|PYRC_MYCBO Dihydroorotase (DHOase)
gi|31618164|emb|CAD94277.1| PROBABLE DIHYDROOROTASE PYRC (DHOase) [Mycobacterium bovis
AF2122/97]
gi|121492958|emb|CAL71429.1| Probable dihydroorotase pyrC [Mycobacterium bovis BCG str. Pasteur
1173P2]
Length = 430
Score = 237 bits (605), Expect = 1e-60, Method: Composition-based stats.
Identities = 144/414 (34%), Positives = 212/414 (51%), Gaps = 6/414 (1%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
G+ ++VD+L+ D +I +I ++ + D + ID + GF+D H H REPG E +
Sbjct: 12 GEGERVDVLVDDGQIAQIGPDLAIPDTADVIDATGHVLLPGFVDLHTHLREPGREYAEDI 71
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRE 130
T S AAA GG+T V M N NPV DS + + ++ P GA+T G E
Sbjct: 72 ETGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGAE 131
Query: 131 LSDMEDI---ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
L++M + A +V F+DDG V +M A+ + L I H E+ L G H
Sbjct: 132 LTEMGMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLTVGAFAH 191
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
EG +A LG+ G P E + +ARD LLA A H+CH SA +V ++ K I +
Sbjct: 192 EGPMAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASAAGTVEILKWAKDQGISI 251
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
T EVTPHHLL D + +G+ ++NPPLR D AL + DG ID +ATDHAPH
Sbjct: 252 TAEVTPHHLLLDDARLASYDGVNRVNPPLREASDAVALRQALADGIIDCVATDHAPHAEH 311
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LE 365
EK + G++G +TA + + V + S + ++MSEN A I LP G+ LE
Sbjct: 312 EKCVEFAAARPGMLGLQTALSVVVQTMVAPGLLSWRDIARVMSENPACIARLPDQGRPLE 371
Query: 366 ENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
A++ V+D + T+ + S+ NTP+ + + T+ GK+ D
Sbjct: 372 VGEPANLTVVDPDATWTVTGADLASRSANTPFESMSLPATVTATLLRGKVTARD 425
>gi|78186875|ref|YP_374918.1| dihydroorotase [Pelodictyon luteolum DSM 273]
gi|78166777|gb|ABB23875.1| Dihydroorotase multifunctional complex type [Pelodictyon luteolum
DSM 273]
Length = 449
Score = 236 bits (601), Expect = 3e-60, Method: Composition-based stats.
Identities = 142/402 (35%), Positives = 215/402 (53%), Gaps = 34/402 (8%)
Query: 37 DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPD 96
+E I ++ + ++ G D H H+REPG KET+ + S AAA GGFT V MPN PV D
Sbjct: 46 EEKVIAMRGKILSPGLFDMHCHFREPGQEYKETLLSGSAAAAAGGFTGVALMPNTTPVID 105
Query: 97 S----------VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDI-ADKVFAFT 145
S L LE+I ++T+ G +L+ + A V A +
Sbjct: 106 SPLGVTFIGYHAGNLPVDLEVI-----------ASMTEGSRGEKLTAFGSLKAYGVRAVS 154
Query: 146 DDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICE 205
DDG +Q++ M A S + I+ HCED SL GG M+EG S++LG+KGIP I E
Sbjct: 155 DDGTAIQASQSMRLAFEYASNFDMLIIQHCEDRSLTTGGVMNEGMWSSKLGLKGIPDISE 214
Query: 206 STQIARDILLAEAANCH----------YHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
+ +ARD++L H YH H+S S++ +RE K++ ++VTCEVTPHH
Sbjct: 215 AMMLARDLMLLRWLEEHKLHDPLCRPRYHAAHVSTAASLQLIREAKRDGLQVTCEVTPHH 274
Query: 256 LLSCDEDI--KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGI 313
D+D+ E G + M PPL ++R+A++ + DGT D IATDHAPH + EK
Sbjct: 275 FTLTDQDLYLAEKKGNFIMKPPLTSPKNRDAVLEALADGTADAIATDHAPHALHEKECPP 334
Query: 314 EKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
++SFGI+G ET+ T+ V + ++ ++L+S N +I LP ++ E A+
Sbjct: 335 GEASFGIIGLETSLGLTMTELVMKGVITMHRAIELLSVNPRRILRLPPIRIREGEKANFT 394
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
+ID E T++ + SK NTP+ ++ G P+ G++
Sbjct: 395 LIDPEAVWTVSADHLRSKSANTPFIGRQLKGRPMGIFHKGRL 436
>gi|118473601|ref|YP_887360.1| dihydroorotase [Mycobacterium smegmatis str. MC2 155]
gi|118174888|gb|ABK75784.1| dihydroorotase [Mycobacterium smegmatis str. MC2 155]
Length = 444
Score = 235 bits (600), Expect = 3e-60, Method: Composition-based stats.
Identities = 143/414 (34%), Positives = 214/414 (51%), Gaps = 6/414 (1%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
G+ VD+L+ D +I +I ++ V + + ID + + + GF+D H H REPG E +
Sbjct: 19 GEGDPVDVLVDDGQIARIGADLPVPETADVIDARGQVLLPGFVDLHTHLREPGREYAEDI 78
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRE 130
T S AAA GG+T V M N +PV D+V + + ++ P GAIT G +
Sbjct: 79 ETGSAAAALGGYTAVFAMANTDPVADTVVVTDHVWRRGQEVGLVDVHPVGAITMGLKGAQ 138
Query: 131 LSDMEDIA---DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
L++M +A +V F+DDG V++ VM A+ + L I H E+ L G H
Sbjct: 139 LTEMGLMAAGAGQVRMFSDDGVCVENPLVMRRALEYATGLGVLIAQHAEEPRLTVGAVAH 198
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
EG +A LG+ G P E + +ARD LLA A H+CH S +V ++ K I +
Sbjct: 199 EGPIAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTAGTVELLKWAKAQGISI 258
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
T EVTPHHLL D ++ +G ++NPPLR ED AL + DG ID +ATDHAPH
Sbjct: 259 TAEVTPHHLLLDDSRLETYDGRNRVNPPLREAEDAAALRQALADGVIDCVATDHAPHAEH 318
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LE 365
EK + G++G +TA + + V+ + + + K+MSE A I LP G+ LE
Sbjct: 319 EKCCEFSVARPGMLGLQTALSVVVETMVRPGLLTWRGVAKVMSEAPAAIVGLPDQGRPLE 378
Query: 366 ENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYID 419
A++ V+D + T+ E S+ NTP+ + T+ G++ D
Sbjct: 379 VGEPANLTVVDPDATWTVAGTELASRSDNTPFETMTLPATVTATLLRGRVTARD 432
>gi|54025592|ref|YP_119834.1| dihydroorotase [Nocardia farcinica IFM 10152]
gi|54017100|dbj|BAD58470.1| putative dihydroorotase [Nocardia farcinica IFM 10152]
Length = 437
Score = 235 bits (600), Expect = 4e-60, Method: Composition-based stats.
Identities = 137/409 (33%), Positives = 211/409 (51%), Gaps = 5/409 (1%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVY 71
G+ + VD+ + + +I +I ++ V D ++ + + + GF+D H H REPG ET+
Sbjct: 13 GEGEPVDVFVDEGEIRQIGTDLGVVDAEIVEARGQVLLPGFVDLHTHLREPGREDTETIE 72
Query: 72 TASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGREL 131
T S AAA GG+T V M N NPV DSV + + ++ P GA+T G++L
Sbjct: 73 TGSAAAALGGYTAVFAMANTNPVADSVVVTDHVWRRGQEVGLVDVHPVGAVTVGLAGKQL 132
Query: 132 SDMEDIADKVFA---FTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
++M +A V F+DDG V +M A+ + L I H E+ L +G HE
Sbjct: 133 AEMGTMAAGVGGVRMFSDDGHCVYDPLIMRRALEYSNSLGVLIAQHAEEPRLTKGAVAHE 192
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G +A LG+ G P E + +ARD LLA A H+CH S +V V+ K I +T
Sbjct: 193 GPTAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTAGTVELVKWAKAQGISIT 252
Query: 249 CEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEE 308
EVTPHHLL D ++ + + K+NPPLR D AL A + +G ID +ATDHAPH ++
Sbjct: 253 AEVTPHHLLLDDSRLETYDAVNKVNPPLREASDTAALRAALAEGIIDCVATDHAPHAEQD 312
Query: 309 KIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNL-PYGK-LEE 366
K + G++G ETA + + V+ + + ++MSE A+I L G+ +
Sbjct: 313 KCCEFAAARPGMLGLETALSIVVETMVRPGLLDWRGVARVMSERPAEIVGLDDQGRPIAV 372
Query: 367 NSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
A++V++D + T+ E S NTP+ +T+ G+I
Sbjct: 373 GEPANLVLVDPDATWTVRASELASISNNTPFEEMTFPARVTMTLLRGRI 421
>gi|148656975|ref|YP_001277180.1| dihydroorotase, multifunctional complex type [Roseiflexus sp. RS-1]
gi|148569085|gb|ABQ91230.1| dihydroorotase, multifunctional complex type [Roseiflexus sp. RS-1]
Length = 497
Score = 234 bits (597), Expect = 8e-60, Method: Composition-based stats.
Identities = 154/449 (34%), Positives = 222/449 (49%), Gaps = 50/449 (11%)
Query: 18 DILIKDDKIEKISENIDVT------DENT--IDVKDRFVTAGFIDAHVHWREPGFSKKET 69
++L+++ K+ ++ + D+T D++T I+ + + GF+D H H REPG KET
Sbjct: 22 NVLVENGKVVQVIDLADLTIAPEPLDDHTEVINARGAVIAPGFLDLHAHVREPGEEHKET 81
Query: 70 VYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR 129
+ TA++AAA GGFTT+ MP+ P D + +I + V+R P GAIT G+
Sbjct: 82 IETATKAAAAGGFTTLCVMPDTRPPIDCAAVARQIRDIARRRGVVRIEPIGAITVGRAGQ 141
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
L++M ++ + F+D+G V A VM A+ + L+ I+AHCED L RG MH+
Sbjct: 142 TLTEMAELVEAGCVGFSDEGNTVMDATVMRNALAYAAMLDTPIMAHCEDVRLTRGWGMHD 201
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G LG+ G P+ E +ARDI LAE H H+CH+S SV +R K +RVT
Sbjct: 202 GAVGIRLGLPGYPAAAEEAMVARDIALAEMTGAHLHICHVSTAGSVALIRAAKARGVRVT 261
Query: 249 CEVTPHHLLSCDE------------------------DIKED----------------NG 268
EVTPHHL D D ED +
Sbjct: 262 AEVTPHHLTLTDRWVLGNLDVPHGEGKSGHRAGRERVDANEDGLDLPSRLKSTLLPPYHT 321
Query: 269 MWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFT 328
++ PPLR +D ALI G+ DGTID IA+DH P + +K ++ GI ETA
Sbjct: 322 STRVRPPLRTEQDVEALIEGLRDGTIDAIASDHEPQSAVDKECEYRLAASGISSLETALG 381
Query: 329 QLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEF 388
L V L LV +E A + L S ADIV+ D + ++P F
Sbjct: 382 -LALTLVHRGKLDLVDLVAKFTEGPATVLGRAPATLRPGSPADIVIFDPDSPWIVDPARF 440
Query: 389 LSKGRNTPYANEKVNGIPVLTISNGKIAY 417
SKGRNTP A +++ G +LT+ G+I +
Sbjct: 441 FSKGRNTPLAGQRLKGQVMLTMYRGQIVF 469
>gi|119357147|ref|YP_911791.1| dihydroorotase, multifunctional complex type [Chlorobium
phaeobacteroides DSM 266]
gi|119354496|gb|ABL65367.1| dihydroorotase, multifunctional complex type [Chlorobium
phaeobacteroides DSM 266]
Length = 446
Score = 234 bits (596), Expect = 9e-60, Method: Composition-based stats.
Identities = 142/400 (35%), Positives = 202/400 (50%), Gaps = 34/400 (8%)
Query: 37 DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPD 96
D+ ID++ + + G D H H+REPG KET+ + S+AA GGFT V MPN PV D
Sbjct: 44 DDRIIDLQGKLLVPGLFDMHCHFREPGQEYKETLESGSKAAVAGGFTGVALMPNTKPVID 103
Query: 97 S----------VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIAD-KVFAFT 145
S + L LE+I GA+++ G +L+ V A +
Sbjct: 104 SPLGVAYIRHNAQQLPVDLEVI-----------GAMSEGSKGEQLAPYGKFRSYGVKAVS 152
Query: 146 DDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICE 205
DDG +Q++ M S + ++ HCED S+ M+EG S +LG+KGIP + E
Sbjct: 153 DDGTAIQNSQNMRLVFQYASNFDLLVIQHCEDKSMTAEAVMNEGVFSTKLGLKGIPDVSE 212
Query: 206 STQIARDILLAE----------AANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
+ + RD+ L A YHV HIS K S+ VR+ K ++VTCEVTPHH
Sbjct: 213 AVMLCRDLHLIRYIVEHELHDPANKPRYHVAHISTKASLDLVRQAKAEGLQVTCEVTPHH 272
Query: 256 LLSCDEDI--KEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGI 313
DED+ G + M PPL +++R A++ + DGTID IATDHAPH EK
Sbjct: 273 FTLTDEDLFNAPSKGNFIMKPPLPSKKNRAAILEAIADGTIDAIATDHAPHAPHEKECPP 332
Query: 314 EKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIV 373
+++SFGI+G ETA T+ V+ I +L ++LMS N KI L + A+
Sbjct: 333 DQASFGIIGLETAVGLTITELVEPGIITLSRAIELMSVNPRKILQLDPLLFAQGERANFT 392
Query: 374 VIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNG 413
+ID E+E + SK NTP+ K+ G + G
Sbjct: 393 IIDPEEEWALTANAVKSKSTNTPFLGRKLKGRAIAVYHKG 432
>gi|126434989|ref|YP_001070680.1| dihydroorotase, multifunctional complex type [Mycobacterium sp.
JLS]
gi|126234789|gb|ABN98189.1| dihydroorotase, multifunctional complex type [Mycobacterium sp.
JLS]
Length = 431
Score = 233 bits (595), Expect = 1e-59, Method: Composition-based stats.
Identities = 141/420 (33%), Positives = 214/420 (50%), Gaps = 6/420 (1%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
G+ VD+L++D +I +I E + + + +D + + GF+D H H REPG E +
Sbjct: 12 GEGDPVDVLVEDGQIAEIGERLSAPEGADAVDAHGQILLPGFVDLHTHLREPGREYAEDI 71
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRE 130
T S AAA GG+T V M N PV DS + + ++ P GA+T G++
Sbjct: 72 ETGSAAAALGGYTAVFAMANTTPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTMGLQGKQ 131
Query: 131 LSDMEDIA---DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
L++M +A +V F+DDG V +M A+ S L I H E+ L G H
Sbjct: 132 LTEMGMMAAGVGQVRMFSDDGVCVDDPLIMRRALEYASGLGVLIAQHAEEPRLTVGAVAH 191
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
EG +A LG+ G P E + + RD LLA A H+CH S +V +R K+ I +
Sbjct: 192 EGPNAARLGLAGWPRAAEESIVIRDALLARDAGARVHICHASTAGTVELLRWAKEQGIAI 251
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
T EVTPHHLL D + +G ++NPPLR D AL + DG ID +ATDHAPH
Sbjct: 252 TAEVTPHHLLLDDSRLATYDGRNRVNPPLREAGDAEALRRALADGVIDCVATDHAPHAEH 311
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LE 365
EK+ + G++G +TA + + V+ + S + ++MSE A+I LP G+ +E
Sbjct: 312 EKMCEFAAARPGMLGLQTALSVVVRTMVEPGLLSWRDVARVMSEAPARIVGLPDQGRPIE 371
Query: 366 ENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKEEINL 425
A++ V+D + T++ S+ NTP+ + LT+ GK+ D + +L
Sbjct: 372 VGEPANLTVVDPDATWTVSGSALASRSDNTPFEEMTLPATVTLTMLRGKVTARDGKSPSL 431
>gi|111024099|ref|YP_707071.1| dihydroorotase [Rhodococcus sp. RHA1]
gi|110823629|gb|ABG98913.1| dihydroorotase [Rhodococcus sp. RHA1]
Length = 447
Score = 233 bits (594), Expect = 2e-59, Method: Composition-based stats.
Identities = 146/427 (34%), Positives = 219/427 (51%), Gaps = 10/427 (2%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENI---DVTDENTIDVKDRFVTAGFIDAHV 57
+L+KN +L G+ + D+L+ D I I + D ID + + GF+D H
Sbjct: 11 VLIKN--VLLYGEGEPTDVLLGDGVIAAIGADAGKDSGPDVEVIDAAGQILLPGFVDLHT 68
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H REPG ET+ + S AAA GG+T V M N +PV DSV + + ++
Sbjct: 69 HLREPGREDTETIDSGSAAAALGGYTAVFAMANTSPVADSVVVTDHVWRRGQEVGLVDVH 128
Query: 118 PYGAITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAH 174
P GA+T G++L++M +A +V F+DDG V +M A+ S L I H
Sbjct: 129 PVGAVTVGLEGKQLAEMATMASGIGRVRMFSDDGHCVYDPLIMRRALEYSSSLGVLIAQH 188
Query: 175 CEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESV 234
E+ L G HEG +A LG+ G P E + +ARD LLA A H+CH S +V
Sbjct: 189 AEEPRLTVGAVAHEGPTAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASTAGTV 248
Query: 235 RAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTI 294
V+ + I +T EVTPHHLL D ++ + + K+NPPLR D AL AG+ +G I
Sbjct: 249 ELVKWARGQGISITAEVTPHHLLLDDSRLETYDAVNKVNPPLREASDVAALRAGLAEGII 308
Query: 295 DIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVA 354
D +ATDHAPH ++K + G++G ETA + + V+T + + ++MSE A
Sbjct: 309 DCVATDHAPHAEQDKCCEFAAARPGMLGLETALSIVAQTMVRTGLLDWRGVARVMSERPA 368
Query: 355 KIFNL-PYGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISN 412
+I L G+ +E A++V+ID + E T++ + S NTPY + + T
Sbjct: 369 EIVGLDDQGRPIEVGEPANLVLIDPDAEWTVHGPDLASVAHNTPYESMTLQARVTTTFLR 428
Query: 413 GKIAYID 419
G++ D
Sbjct: 429 GRVTASD 435
>gi|108799331|ref|YP_639528.1| dihydroorotase, multifunctional complex type [Mycobacterium sp.
MCS]
gi|119868447|ref|YP_938399.1| dihydroorotase, multifunctional complex type [Mycobacterium sp.
KMS]
gi|108769750|gb|ABG08472.1| dihydroorotase, multifunctional complex type [Mycobacterium sp.
MCS]
gi|119694536|gb|ABL91609.1| dihydroorotase, multifunctional complex type [Mycobacterium sp.
KMS]
Length = 431
Score = 233 bits (593), Expect = 3e-59, Method: Composition-based stats.
Identities = 140/420 (33%), Positives = 214/420 (50%), Gaps = 6/420 (1%)
Query: 12 GKFKKVDILIKDDKIEKISENIDVTD-ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
G+ VD+L++D +I +I E + + + +D + + GF+D H H REPG E +
Sbjct: 12 GEGDPVDVLVEDGQIAEIGERLSAPEGADAVDAHGQILLPGFVDLHTHLREPGREYAEDI 71
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRE 130
T S AAA GG+T V M N PV DS + + ++ P GA+T G++
Sbjct: 72 ETGSAAAALGGYTAVFAMANTTPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTMGLQGKQ 131
Query: 131 LSDMEDIA---DKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMH 187
L++M +A +V F+DDG V +M A+ S L I H E+ L G H
Sbjct: 132 LTEMGMMAAGVGQVRMFSDDGVCVDDPLIMRRALEYASGLGVLIAQHAEEPRLTVGAVAH 191
Query: 188 EGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRV 247
EG +A LG+ G P E + + RD LLA A H+CH S +V +R K+ I +
Sbjct: 192 EGPNAARLGLAGWPRAAEESIVIRDALLARDAGARVHICHASTAGTVELLRWAKEQGIAI 251
Query: 248 TCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTME 307
T EVTPHHLL D + +G ++NPPLR D AL + DG ID +ATDHAPH
Sbjct: 252 TAEVTPHHLLLDDSRLATYDGRNRVNPPLREAGDAEALRRALADGVIDCVATDHAPHAEH 311
Query: 308 EKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP-YGK-LE 365
EK+ + G++G +TA + + V+ + S + ++MSE A+I LP G+ +E
Sbjct: 312 EKMCEFAAARPGMLGLQTALSVVVRTMVEPGLLSWRDVARVMSEAPARIVGLPDQGRPIE 371
Query: 366 ENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYIDKEEINL 425
A++ V+D + T++ S+ NTP+ + +T+ GK+ D + +L
Sbjct: 372 VGEPANLTVVDPDATWTVSGSALASRSDNTPFEEMTLPATVTMTMLRGKVTARDGKSPSL 431
>gi|78358005|ref|YP_389454.1| dihydroorotase, multifunctional complex type [Desulfovibrio
desulfuricans G20]
gi|78220410|gb|ABB39759.1| dihydroorotase, multifunctional complex type [Desulfovibrio
desulfuricans G20]
Length = 426
Score = 233 bits (593), Expect = 3e-59, Method: Composition-based stats.
Identities = 145/396 (36%), Positives = 206/396 (52%), Gaps = 7/396 (1%)
Query: 15 KKVDILIKDDKIEKISENIDV---TDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVY 71
+ VD+ + +I +SE+ T++ + + FID HVH REPGF KE +
Sbjct: 19 RTVDVTVSGGRIAAVSEHGAAPAPQHAETVEAAGKILFPSFIDCHVHLREPGFEYKEDIA 78
Query: 72 TASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKN--DSVIRAIPYGAITKEEYGR 129
+ AAA GGF V+ M N +PV D LE + R P GA TK G
Sbjct: 79 SGLAAAAHGGFGAVLPMANTSPVNDQGSVTELMLERARKAWPHGPRVHPVGAATKGLKGE 138
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
EL+ M ++A AF++DG V A + M + K ++ HCED SL RG M+E
Sbjct: 139 ELAPMGELAAAGCVAFSNDGLPVGGAEMFRRCMEYAADFGKIVIDHCEDPSLARGTHMNE 198
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G S LG+KG + ES Q+ARDILLAE H+ HIS ++SV + K+ +RVT
Sbjct: 199 GVTSGRLGVKGQSVVAESVQVARDILLAEYLGIPVHLAHISCRQSVELIAWAKQRGVRVT 258
Query: 249 CEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEE 308
E PH+LL D +++ + K+NPPLR +D A+ V DGTIDI+ TDHAPH E
Sbjct: 259 AETCPHYLLLDDLALEQYSTAAKVNPPLRTPDDVAAMRRAVADGTIDILVTDHAPHAAHE 318
Query: 309 KIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENS 368
K ++++ GI G +TA L + V+ + + +V+L +F LP +
Sbjct: 319 KDTPLDEAPNGISGLDTA-VALTWRLVQEGLLTEADMVRLWCHAPGSLFRLPVNRFTAGD 377
Query: 369 FADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNG 404
AD + D E T+ PE SKG+NTP+ K+ G
Sbjct: 378 PADFFLFDPAHEWTVTPEAMHSKGKNTPFTGWKLTG 413
>gi|67937862|ref|ZP_00530392.1| Dihydroorotase multifunctional complex type [Chlorobium
phaeobacteroides BS1]
gi|67915723|gb|EAM65041.1| Dihydroorotase multifunctional complex type [Chlorobium
phaeobacteroides BS1]
Length = 440
Score = 232 bits (591), Expect = 4e-59, Method: Composition-based stats.
Identities = 137/392 (34%), Positives = 203/392 (51%), Gaps = 34/392 (8%)
Query: 36 TDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVP 95
+ + ID+ + + +G D H H+REPG KET+ T SRAA GGFT V MPN PV
Sbjct: 45 SHDRVIDMSGKIIASGLFDMHCHFREPGQEYKETLETGSRAAVAGGFTGVAVMPNTKPVI 104
Query: 96 DS----------VETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIAD-KVFAF 144
DS + L +EI+ A+T+ G LS ++ + +
Sbjct: 105 DSPLGAAFIKLNAKDLPVDIEIV-----------AAMTEGSQGETLSSYGKLSSYGISSI 153
Query: 145 TDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSIC 204
+DDG VQ+ +M + + ++ HCED SL + G M+EG SA +G+KGIP +
Sbjct: 154 SDDGTAVQTTRMMRLVFEYAASFDMLVIQHCEDTSLSKEGVMNEGGYSALMGLKGIPDVA 213
Query: 205 ESTQIARDILLAEAANCH----------YHVCHISAKESVRAVREGKKNNIRVTCEVTPH 254
E +ARDI L + H YHV HIS K ++ VR+ + +++TCEVTPH
Sbjct: 214 EVITLARDIHLIDYLQKHKLNPPISPPRYHVAHISTKGALDLVRQARAKGMKITCEVTPH 273
Query: 255 HLLSCDEDIKE--DNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRG 312
H ++D+ E + G + M PPL E+R+A++ + DGTID IA DHAPH EK
Sbjct: 274 HFTLTEQDLYEADNKGNYIMKPPLCSSENRDAILEALSDGTIDAIACDHAPHARHEKECP 333
Query: 313 IEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADI 372
++ +FGI+G ET+ +++ V T + ++L+S N KI L + E S A+
Sbjct: 334 ADQVAFGIIGLETSVGLTFSELVHTGKITDYRAIELLSSNPRKIMGLSPIRFEPGSPANF 393
Query: 373 VVIDLEKEITINPEEFLSKGRNTPYANEKVNG 404
ID E+ T + SK RNTP+ + G
Sbjct: 394 TFIDPEETWTCTEDLIRSKSRNTPFLGRTMKG 425
>gi|154508779|ref|ZP_02044421.1| hypothetical protein ACTODO_01288 [Actinomyces odontolyticus ATCC
17982]
gi|153798413|gb|EDN80833.1| hypothetical protein ACTODO_01288 [Actinomyces odontolyticus ATCC
17982]
Length = 439
Score = 231 bits (588), Expect = 9e-59, Method: Composition-based stats.
Identities = 135/384 (35%), Positives = 200/384 (52%), Gaps = 5/384 (1%)
Query: 35 VTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPV 94
V D ID + G +D H H R+PG ETV+T +RAAA GG+T V M N P
Sbjct: 41 VRDPRIIDAEGLIALPGLVDIHTHLRQPGGEDAETVFTGTRAAAVGGYTAVHAMANTTPT 100
Query: 95 PDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIA---DKVFAFTDDGRGV 151
D+ +++ L + + + P GA+TK G++L+ + +A KV F+DDG+ V
Sbjct: 101 QDTAAIVDQVLRLGEEADWVEVRPVGAVTKGLEGKQLASLGSMARSRSKVRVFSDDGKCV 160
Query: 152 QSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIAR 211
+M A+ I H +D +L G M+E S ELG+ G P++ E IAR
Sbjct: 161 SDPVLMRRALEYVKGFGGVIAQHSQDPALTEGAQMNESTLSGELGLAGWPAVAEEAIIAR 220
Query: 212 DILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWK 271
DILLA+ HVCH+S SV VR GK + +T E TPHHLL ++ + ++K
Sbjct: 221 DILLAKHVGSRLHVCHLSTAGSVDLVRWGKAQGVDITAEATPHHLLLTEQLAATYDPLYK 280
Query: 272 MNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLY 331
+NPPLR ED A+ G+ DGTID I TDHAPH +E K + +FG+ G ETA +
Sbjct: 281 VNPPLRRAEDVEAVREGLADGTIDCIGTDHAPHPLEMKDCEWQAGAFGMTGLETALPIII 340
Query: 332 TKFVKTDIFSLEMLVKLMSENVAKIFNL-PYGK-LEENSFADIVVIDLEKEITINPEEFL 389
V T + ++MS A+I + G+ L + A + ++D +T++P +
Sbjct: 341 ETMVNTGRMDWADVARVMSTVPAQIGCVKSQGQGLVVGAPAHVTLVDATVRVTVDPAKQW 400
Query: 390 SKGRNTPYANEKVNGIPVLTISNG 413
++ N P+ ++ G TI NG
Sbjct: 401 TRSTNCPFRGMELPGQVRYTIYNG 424
>gi|149177848|ref|ZP_01856447.1| dihydroorotase, multifunctional complex type [Planctomyces maris
DSM 8797]
gi|148843338|gb|EDL57702.1| dihydroorotase, multifunctional complex type [Planctomyces maris
DSM 8797]
Length = 426
Score = 231 bits (588), Expect = 1e-58, Method: Composition-based stats.
Identities = 150/423 (35%), Positives = 224/423 (52%), Gaps = 10/423 (2%)
Query: 1 MLLKNCKILKNGKF--KKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +I+ + + ++LI++ KI + E VT + TID V+ GFID HV
Sbjct: 4 ILIKNGRIIDPSQDLDQLGNLLIENGKITGLCEAT-VTADETIDATGLIVSPGFIDIHVS 62
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPD---SVETLNKQLEIIKNDSVIR 115
EPGF + ET+ + + AA GG T++ +PN +PV D S E + Q E N V
Sbjct: 63 LCEPGFEEDETIESGTAAALAGGVTSLGCLPNTSPVVDDRSSAEFILLQAERAANCHVY- 121
Query: 116 AIPYGAITKEEYGRELSDM-EDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAH 174
P GAITK G+EL+++ + +A K FTD R + +A +M A+ ++ I+
Sbjct: 122 --PLGAITKNHEGKELAEIGQLVAGKAVGFTDADRPIDNAQIMRCALEYTRMFDRPILNR 179
Query: 175 CEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESV 234
+ L G MHEG S LG+KGIPS E + RDI LAE H+ IS + SV
Sbjct: 180 PQVAELTDKGQMHEGFYSTVLGLKGIPSAAEEIMVNRDIALAELTRGRIHLMCISTQNSV 239
Query: 235 RAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTI 294
+R K IRV+ +VTPHHL D+ ++ + +K+ PPLR +E +ALI G+ DGTI
Sbjct: 240 SQIRRAKAAGIRVSADVTPHHLTLTDQMLENYDPNFKVLPPLRSQEHIDALIEGLKDGTI 299
Query: 295 DIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVA 354
D I +DH PH E+K I + FGI+G ET + S L+ ++ A
Sbjct: 300 DAICSDHTPHAAEKKTDEILGADFGIIGLETLLPVCLQSLITPGHLSWPELIGKLTRGPA 359
Query: 355 KIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGK 414
+I L G L E + ADI +I+ + + P S NTP+ +++ G + I +G+
Sbjct: 360 QILGLEKGTLAEGADADITLINPDIRYILEPALLKSSSHNTPFLGKELQGRAEVVIVSGE 419
Query: 415 IAY 417
I +
Sbjct: 420 IRF 422
>gi|23014542|ref|ZP_00054353.1| COG0044: Dihydroorotase and related cyclic amidohydrolases
[Magnetospirillum magnetotacticum MS-1]
Length = 436
Score = 229 bits (583), Expect = 3e-58, Method: Composition-based stats.
Identities = 127/378 (33%), Positives = 201/378 (53%), Gaps = 2/378 (0%)
Query: 41 IDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVET 100
+D + + G +D V REPG KET+ +A AA GG T+++ +PN NPV D V T
Sbjct: 56 VDCQGLCLAPGLVDMRVQLREPGEEHKETLKSAGEAAVAGGVTSMVCLPNTNPVIDEVAT 115
Query: 101 LNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYE 159
+ + + + PY A TK G+EL++M +A+ FTD R +++A VM
Sbjct: 116 VEFVARRARKIGLAKVYPYAAATKRVEGKELAEMGMLAEAGALGFTDGIRAIRNAQVMRR 175
Query: 160 AMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAA 219
A+ + IV H E+ SL GG M+EG+ + +G+ GIP E+ + RD+ L E
Sbjct: 176 ALTYAATFGLLIVQHPEEPSLAEGGMMNEGELATRMGLSGIPVAAEAIMLERDMRLVEIT 235
Query: 220 NCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGR 279
YH HI+ +E V +R+ K + VTC+ P + + +K+ K++PPLR
Sbjct: 236 GGRYHAAHIATREGVEIIRKAKAKGLSVTCDTAPPYFALNELAVKDYRTFAKLSPPLRSE 295
Query: 280 EDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDI 339
DR A++ G+ DGTID +A+DH+P + K + FG VG ET +
Sbjct: 296 PDRLAVVEGLRDGTIDAVASDHSPQDQDSKRVPFAVAEFGGVGLETLLA-VTLDLAHNGH 354
Query: 340 FSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYAN 399
SL +KL++ A I NL G+L+ + AD+V+ D ++ +N + F SK +N+P+ +
Sbjct: 355 MSLIEALKLVTCAPASILNLAAGRLKVGAAADLVLFDPDRGWKVNAKTFHSKSKNSPFDD 414
Query: 400 EKVNGIPVLTISNGKIAY 417
V G+ + TI +G+ Y
Sbjct: 415 RPVQGMVMRTIVDGRTVY 432
>gi|148998423|ref|ZP_01825865.1| dihydroorotase [Streptococcus pneumoniae SP11-BS70]
gi|147755820|gb|EDK62865.1| dihydroorotase [Streptococcus pneumoniae SP11-BS70]
Length = 422
Score = 228 bits (580), Expect = 8e-58, Method: Composition-based stats.
Identities = 152/421 (36%), Positives = 222/421 (52%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+G + D+L++D KI KI+ I TID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETIDATGHVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GGFTTV+ M N +P VETL L+ + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEK-INVKT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
ITK G+ L+D + + + F+DDG ++S+ ++ EAM KLN I H ED
Sbjct: 121 VATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +E I G + E +ARD+++A A H H+ H+S +ESV+ V
Sbjct: 181 PGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ VT EV P H + + KMNPPLR DR A+I G+ G I +I
Sbjct: 241 EFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH ++EK + I K+ G+ G ET+ + T V+ SL L++ M+ N AK+
Sbjct: 301 ATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLGLTYLVEAGELSLMELLEKMTYNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN ADI + D + + ++ F SK N+P+ E + G TI G+I
Sbjct: 361 YNFKAGYLAENGPADITIFDAKADRLVD-SHFASKAANSPFIGETLKGQVKYTICKGQIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|15903097|ref|NP_358647.1| dihydroorotase [Streptococcus pneumoniae R6]
gi|116515810|ref|YP_816504.1| dihydroorotase [Streptococcus pneumoniae D39]
gi|73621436|sp|Q8DPQ5|PYRC_STRR6 Dihydroorotase (DHOase)
gi|15458674|gb|AAK99857.1| Dihydroorotase [Streptococcus pneumoniae R6]
gi|116076386|gb|ABJ54106.1| dihydroorotase [Streptococcus pneumoniae D39]
Length = 422
Score = 228 bits (580), Expect = 8e-58, Method: Composition-based stats.
Identities = 152/421 (36%), Positives = 222/421 (52%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+G + D+L++D KI KI+ I TID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETIDATGHVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GGFTTV+ M N +P VETL L+ + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEK-INVKT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
ITK G+ L+D + + + F+DDG ++S+ ++ EAM KLN I H ED
Sbjct: 121 VATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +E I G + E +ARD+++A A H H+ H+S +ESV+ V
Sbjct: 181 PGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ VT EV P H + + KMNPPLR DR A+I G+ G I +I
Sbjct: 241 EFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH ++EK + I K+ G+ G ET+ + T V+ SL L++ M+ N AK+
Sbjct: 301 ATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLGLTYLVEAGELSLMELLEKMTYNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN ADI + D + + ++ F SK N+P+ E + G TI G+I
Sbjct: 361 YNFEAGYLAENGPADITIFDAKADRLVD-SHFASKAANSPFIGETLKGQVKYTICKGQIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|15901032|ref|NP_345636.1| dihydroorotase [Streptococcus pneumoniae TIGR4]
gi|111658295|ref|ZP_01408985.1| hypothetical protein SpneT_02000524 [Streptococcus pneumoniae
TIGR4]
gi|149013097|ref|ZP_01833943.1| dihydroorotase [Streptococcus pneumoniae SP19-BS75]
gi|73621434|sp|Q97QN4|PYRC_STRPN Dihydroorotase (DHOase)
gi|14972646|gb|AAK75276.1| dihydroorotase, multifunctional complex type [Streptococcus
pneumoniae TIGR4]
gi|147763042|gb|EDK69985.1| dihydroorotase [Streptococcus pneumoniae SP19-BS75]
Length = 422
Score = 227 bits (579), Expect = 1e-57, Method: Composition-based stats.
Identities = 152/421 (36%), Positives = 222/421 (52%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+G + D+L++D KI KI+ I TID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETIDATGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GGFTTV+ M N +P VETL L+ + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEK-INVKT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
ITK G+ L+D + + + F+DDG ++S+ ++ EAM KLN I H ED
Sbjct: 121 VATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +E I G + E +ARD+++A A H H+ H+S +ESV+ V
Sbjct: 181 PGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ VT EV P H + + KMNPPLR DR A+I G+ G I +I
Sbjct: 241 EFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH ++EK + I K+ G+ G ET+ + T V+ SL L++ M+ N AK+
Sbjct: 301 ATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLSLTYLVEAGELSLMELLEKMTYNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN ADI + D + + ++ F SK N+P+ E + G TI G+I
Sbjct: 361 YNFEAGYLAENGPADITIFDAKADRFVD-SHFASKAANSPFIGETLKGQVKYTICKGQIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|148994517|ref|ZP_01823697.1| dihydroorotase [Streptococcus pneumoniae SP9-BS68]
gi|147927187|gb|EDK78223.1| dihydroorotase [Streptococcus pneumoniae SP9-BS68]
Length = 422
Score = 227 bits (578), Expect = 1e-57, Method: Composition-based stats.
Identities = 152/421 (36%), Positives = 222/421 (52%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+G + D+L++D KI KI+ I TID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETIDATGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GGFTTV+ M N +P VETL L+ + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEK-INVKT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
ITK G+ L+D + + + F+DDG ++S+ ++ EAM KLN I H ED
Sbjct: 121 VATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +E I G + E +ARD+++A A H H+ H+S +ESV+ V
Sbjct: 181 PGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ VT EV P H + + KMNPPLR DR A+I G+ G I +I
Sbjct: 241 EFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH ++EK + I K+ G+ G ET+ + T V+ SL L++ M+ N AK+
Sbjct: 301 ATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLSLTYLVEAGELSLMELLEKMTYNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN ADI + D + + ++ F SK N+P+ E + G TI G+I
Sbjct: 361 YNFEAGYLAENGPADITIFDAKADRFVD-SHFASKAANSPFIGETLKGQVKYTICKGQIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|77408051|ref|ZP_00784799.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae COH1]
gi|77173316|gb|EAO76437.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae COH1]
Length = 430
Score = 227 bits (578), Expect = 1e-57, Method: Composition-based stats.
Identities = 150/420 (35%), Positives = 221/420 (52%), Gaps = 12/420 (2%)
Query: 8 ILKNG-------KFKKV-DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
I+KNG F +V D+LI KI++IS+ ID+ ID ++ V G +D HVH+
Sbjct: 3 IIKNGLIIDPQSGFNQVSDMLIDQGKIKQISKEIDIKGIPIIDASNKIVAPGLVDIHVHF 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG + KE ++T + +AA GGFTTV+ M N NP S E + KQ++ I+
Sbjct: 63 REPGQTHKENIHTGALSAAAGGFTTVLMMANTNPTISSSEIV-KQVKESAAKEAIKIETV 121
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
ITK G++L + E++ + V F+DDG + V+ EAM + K + + H ED
Sbjct: 122 ATITKSLNGKDLVNFEELLEAGVAGFSDDGIPLTDTKVLQEAMNLARKHDVVLSLHEEDP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL ++E + G + E + IARD ++A H+ H+S+ ESV V
Sbjct: 182 SLNGVLGINEHIAQKIYHVCGASGLAEYSMIARDAMIAYQTQAKVHIQHLSSSESVEVVD 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+K +T EVTP H ++ + K+NPPLR +DR ALI G+ G I IIA
Sbjct: 242 FAQKLGANLTAEVTPQHFSKTEDLLLTKGANAKLNPPLRLEKDRQALIDGLKSGVISIIA 301
Query: 299 TDHAP-HTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
+DHAP H ME+ I ++ G+ G ET+ T V T S+ + M+ N A+++
Sbjct: 302 SDHAPHHIMEKAADNISQAPSGMTGLETSLALGITYLVSTKELSMIDFLAKMTCNPAQLY 361
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G L E ADIV+ D +E I EF SK N+P+ +K+ G+ TI NG+I Y
Sbjct: 362 GFDAGYLREGGPADIVIFDQAEERIIKA-EFASKSSNSPFIGDKLKGVVHYTICNGEIVY 420
>gi|148989199|ref|ZP_01820589.1| dihydroorotase [Streptococcus pneumoniae SP6-BS73]
gi|149006173|ref|ZP_01829885.1| dihydroorotase [Streptococcus pneumoniae SP18-BS74]
gi|147761950|gb|EDK68912.1| dihydroorotase [Streptococcus pneumoniae SP18-BS74]
gi|147925422|gb|EDK76500.1| dihydroorotase [Streptococcus pneumoniae SP6-BS73]
Length = 422
Score = 227 bits (578), Expect = 1e-57, Method: Composition-based stats.
Identities = 152/421 (36%), Positives = 222/421 (52%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+G + D+L++D KI KI+ I TID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETIDATGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GGFTTV+ M N +P VETL L+ + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEK-INVKT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
ITK G+ L+D + + + F+DDG ++S+ ++ EAM KLN I H ED
Sbjct: 121 VATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +E I G + E +ARD+++A A H H+ H+S +ESV+ V
Sbjct: 181 PGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ VT EV P H + + KMNPPLR DR A+I G+ G I +I
Sbjct: 241 EFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH ++EK + I K+ G+ G ET+ + T V+ SL L++ M+ N AK+
Sbjct: 301 ATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLGLTYLVEAGELSLMELLEKMTYNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN ADI + D + + ++ F SK N+P+ E + G TI G+I
Sbjct: 361 YNFEAGYLAENGPADITIFDAKADRLVD-SHFASKAANSPFIGETLKGQVKYTICKGQIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|77414500|ref|ZP_00790648.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae 515]
gi|77159450|gb|EAO70613.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae 515]
Length = 430
Score = 226 bits (577), Expect = 2e-57, Method: Composition-based stats.
Identities = 150/420 (35%), Positives = 221/420 (52%), Gaps = 12/420 (2%)
Query: 8 ILKNG-------KFKKV-DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
I+KNG F +V D+LI KI++IS+ ID+ ID ++ V G +D HVH+
Sbjct: 3 IIKNGLIIDPQSGFNQVSDMLIDQGKIKQISKEIDIKGIPIIDASNKIVAPGLVDIHVHF 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG + KE ++T + +AA GGFTTV+ M N NP S+E + KQ++ I+
Sbjct: 63 REPGQTHKENIHTGALSAAAGGFTTVLMMANTNPTISSLEIV-KQVKESAAKEAIKIETV 121
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
ITK G++L + E++ + V F+DDG + V+ EAM + K + + H ED
Sbjct: 122 ATITKSLNGKDLVNFEELLEAGVAGFSDDGIPLTDTKVLQEAMNLARKHDVVLSLHEEDP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL ++E + G + E + IARD ++A H+ H+S+ ESV V
Sbjct: 182 SLNGVLGINEHIAQKIYHVCGASGLAEYSMIARDAMIAYQTQAKVHIQHLSSSESVEVVD 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+K +T EVTP H ++ + K+NPPLR +DR ALI G+ G I IIA
Sbjct: 242 FAQKLGANLTAEVTPQHFSKTEDLLLTKGANAKLNPPLRLEKDRQALIDGLKSGVISIIA 301
Query: 299 TDHAP-HTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
+DHAP H ME+ I + G+ G ET+ T V T S+ + M+ N A+++
Sbjct: 302 SDHAPHHIMEKAADNISQVPSGMTGLETSLALGITYLVSTKELSMIDFLAKMTCNPAQLY 361
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G L E ADIV+ D +E I EF SK N+P+ +K+ G+ TI NG+I Y
Sbjct: 362 GFDAGYLREGGPADIVIFDQAEERIIKA-EFASKSSNSPFIGDKLKGVVHYTICNGEIVY 420
>gi|77406304|ref|ZP_00783369.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae H36B]
gi|77175080|gb|EAO77884.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae H36B]
Length = 430
Score = 226 bits (577), Expect = 2e-57, Method: Composition-based stats.
Identities = 150/420 (35%), Positives = 220/420 (52%), Gaps = 12/420 (2%)
Query: 8 ILKNG-------KFKKV-DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
I+KNG F +V D+LI KI++IS+ ID+ ID ++ V G +D HVH+
Sbjct: 3 IIKNGLIIDPQSGFNQVSDMLIDQGKIKQISKEIDIKGIPIIDASNKIVAPGLVDIHVHF 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG + KE ++T + +AA GGFTTV+ M N NP S E + KQ++ I+
Sbjct: 63 REPGQTHKENIHTGALSAAAGGFTTVLMMANTNPTISSPEIV-KQVKESAAKEAIKIETV 121
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
ITK G++L + E++ + V F+DDG + V+ EAM + K + + H ED
Sbjct: 122 ATITKSLNGKDLVNFEELLEAGVAGFSDDGIPLTDTKVLQEAMNLARKHDVVLSLHEEDP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL ++E + G + E + IARD ++A H+ H+S+ ESV V
Sbjct: 182 SLNGVLGINEHIAQKIYHVCGASGLAEYSMIARDAMIAYQTQAKVHIQHLSSSESVEVVD 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+K +T EVTP H ++ + K+NPPLR +DR ALI G+ G I IIA
Sbjct: 242 FAQKLGANLTAEVTPQHFSKTEDLLLTKGANAKLNPPLRLEKDRQALIDGLKSGVISIIA 301
Query: 299 TDHAP-HTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
+DHAP H ME+ I ++ G+ G ET T V T S+ + M+ N A+++
Sbjct: 302 SDHAPHHIMEKAADNISQAPSGMTGLETTLALGITYLVSTKELSMIDFLAKMTCNPAQLY 361
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G L E ADIV+ D +E I EF SK N+P+ +K+ G+ TI NG+I Y
Sbjct: 362 GFDAGYLREGGPADIVIFDQAQERIIKA-EFASKSSNSPFIGDKLKGVVHYTICNGEIVY 420
>gi|117928507|ref|YP_873058.1| dihydroorotase, multifunctional complex type [Acidothermus
cellulolyticus 11B]
gi|117648970|gb|ABK53072.1| dihydroorotase, multifunctional complex type [Acidothermus
cellulolyticus 11B]
Length = 428
Score = 226 bits (577), Expect = 2e-57, Method: Composition-based stats.
Identities = 144/423 (34%), Positives = 212/423 (50%), Gaps = 8/423 (1%)
Query: 2 LLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWRE 61
LL+ +IL DILI D I +I + +D V G +D H H RE
Sbjct: 5 LLRGGRILGG---DPADILIAGDSIAEIGAGLTAAGAEIVDAGGLVVLPGLVDLHTHLRE 61
Query: 62 PGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGA 121
PG ET+ + + AAA GGFT V M N +PV D+ + + P GA
Sbjct: 62 PGREDAETIESGTLAAALGGFTAVHAMANTDPVADTAGVVEQVWLAGHEAGHCDVAPVGA 121
Query: 122 ITKEEYGRELSDMEDIAD---KVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
+T G L+++ +AD +V F+DDGR V +M A+ + I H ++
Sbjct: 122 VTVGLAGERLAELGAMADSHARVRVFSDDGRCVADPLLMRRALEYVKAFDGVIAQHAQEP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
L ++EG+ SA LG+ G P+ E + IARD+LLA H+CH+S SV +R
Sbjct: 182 RLTEDAQLNEGEVSARLGLAGWPAAAEESIIARDVLLAGHVGSRVHICHVSTAGSVELIR 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
K I VT EVTPHHLL D+ + ++K+NPPLR D AL AG+ DGTID +A
Sbjct: 242 WAKARGIAVTAEVTPHHLLLTDDLAVSYDPVFKVNPPLRTAADVAALRAGLADGTIDAVA 301
Query: 299 TDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFN 358
TDHAPH +E K ++ G++G +TA + + V+T + + MS A+I
Sbjct: 302 TDHAPHPVEAKECEWAAAAPGMIGLQTALSVVALAMVETGLLDWAGVADRMSIRPARIGR 361
Query: 359 L-PYGK-LEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
L +G+ + S A++ +ID + P +SK RNTP+ +++ V T +G
Sbjct: 362 LTTHGRPIAVGSPANLTLIDPTARWVVEPSVLVSKSRNTPFLGKELPVRVVHTFLHGTPT 421
Query: 417 YID 419
+D
Sbjct: 422 VLD 424
>gi|76788409|ref|YP_329756.1| dihydroorotase [Streptococcus agalactiae A909]
gi|76563466|gb|ABA46050.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae A909]
Length = 430
Score = 226 bits (577), Expect = 2e-57, Method: Composition-based stats.
Identities = 150/420 (35%), Positives = 221/420 (52%), Gaps = 12/420 (2%)
Query: 8 ILKNG-------KFKKV-DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
I+KNG F +V D+LI KI++IS+ ID+ ID ++ V G +D HVH+
Sbjct: 3 IIKNGLIIDPQSGFNQVSDMLIDQGKIKQISKEIDIKGIPIIDASNKIVAPGLVDIHVHF 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG + KE ++T + +AA GGFTTV+ M N NP S E + KQ++ I+
Sbjct: 63 REPGQTHKENIHTGALSAAAGGFTTVLMMANTNPTISSPEIV-KQVKESAAKEAIKIETV 121
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
ITK G++L + E++ + V F+DDG + V+ EAM + K + + H ED
Sbjct: 122 ATITKSLNGKDLVNFEELLEAGVAGFSDDGIPLTDTKVLQEAMNLARKHDVVLSLHEEDP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL ++E + G + E + IARD ++A H+ H+S+ ESV V
Sbjct: 182 SLNGVLGINEHIAQKIYHVCGASGLAEYSMIARDAMIAYQTQAKVHIQHLSSSESVEVVD 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+K +T EVTP H ++ + K+NPPLR +DR ALI G+ G I IIA
Sbjct: 242 FAQKLGANLTAEVTPQHFSKTEDLLLTKGANAKLNPPLRLEKDRQALIDGLKRGVISIIA 301
Query: 299 TDHAP-HTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
+DHAP H ME+ I ++ G+ G ET+ T V T S+ + M+ N A+++
Sbjct: 302 SDHAPHHIMEKAADNISQAPSGMTGLETSLALGITYLVSTKELSMIDFLAKMTCNPAQLY 361
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G L E ADIV+ D +E I EF SK N+P+ +K+ G+ TI NG+I Y
Sbjct: 362 GFDAGYLREGGPADIVIFDQAQERIIKA-EFASKSSNSPFIGDKLKGVVHYTICNGEIVY 420
>gi|55821079|ref|YP_139521.1| dihydroorotase [Streptococcus thermophilus LMG 18311]
gi|55823005|ref|YP_141446.1| dihydroorotase [Streptococcus thermophilus CNRZ1066]
gi|73621437|sp|Q5LZQ6|PYRC_STRT1 Dihydroorotase (DHOase)
gi|73621438|sp|Q5M4C1|PYRC_STRT2 Dihydroorotase (DHOase)
gi|55737064|gb|AAV60706.1| dihydroorotase [Streptococcus thermophilus LMG 18311]
gi|55738990|gb|AAV62631.1| dihydroorotase [Streptococcus thermophilus CNRZ1066]
Length = 422
Score = 226 bits (576), Expect = 2e-57, Method: Composition-based stats.
Identities = 150/422 (35%), Positives = 228/422 (54%), Gaps = 8/422 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+G + D+L+ K+ KI+ENID D ID V G +D HVH
Sbjct: 2 LLIKNGRVVDPKSGLDTQADVLVDGKKVVKIAENIDAGDAQVIDATGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSV-IRAI 117
+REPG + KE ++T + AAA GGFTTV+ M N NP ETL + L +++ I+++
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTNPTISDKETLKEVLTSAAKENIHIKSV 121
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
ITK G ++D + + + F+DDG + +A ++ +AM + + N I H E
Sbjct: 122 --ATITKNFDGENITDFKGLLEAGAVGFSDDGIPLTNAGIVKKAMELAKENNTFISLHEE 179
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D L +E E I G + E + IARD+++A H H+ H+S ESV+
Sbjct: 180 DPDLNGVLGFNENIAKKEFHICGATGVAEYSMIARDVMVAYDTQAHVHIQHLSKAESVKV 239
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
V +K +VT EV P H ++ + KMNPPLR DR A+I G+ G I +
Sbjct: 240 VEFAQKLGAQVTAEVAPQHFSKTEDLLLSKGANAKMNPPLRLESDRQAVIEGLKSGVISV 299
Query: 297 IATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IATDHAPH +EK + + K+ G+ G ET+ + T V+ SL L+KLM+ N +
Sbjct: 300 IATDHAPHHADEKNVADVTKAPSGMTGLETSLSLGLTYLVEAGHLSLTELLKLMTSNPSD 359
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
++ G L EN AD+V+ +KE +F SK N+P+ E++ G TI +G+I
Sbjct: 360 LYGFDAGYLAENGPADLVIF-ADKEKRQVTADFKSKAANSPFVGEELTGSVKYTICDGEI 418
Query: 416 AY 417
Y
Sbjct: 419 VY 420
>gi|148985777|ref|ZP_01818905.1| dihydroorotase [Streptococcus pneumoniae SP3-BS71]
gi|147922081|gb|EDK73204.1| dihydroorotase [Streptococcus pneumoniae SP3-BS71]
Length = 422
Score = 226 bits (575), Expect = 3e-57, Method: Composition-based stats.
Identities = 152/421 (36%), Positives = 221/421 (52%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN ++ K+G + D+L++D KI KI+ I TID V G +D HVH
Sbjct: 2 LLIKNGHVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETIDATGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GGFTTV+ M N +P VETL L+ + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEK-INVKT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
ITK G+ L+D + + + F+DDG ++S+ ++ EAM KLN I H ED
Sbjct: 121 VATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +E I G + E +ARD+++A A H H+ H+S +ESV+ V
Sbjct: 181 PGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ VT EV P H + + KMNPPLR DR A+I G+ G I +I
Sbjct: 241 EFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH ++EK + I K+ G+ G ET+ + T V+ SL L++ M+ N AK+
Sbjct: 301 ATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLGLTYLVEAGELSLMELLEKMTYNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN ADI + D + + ++ F SK N+P+ E + G TI G+I
Sbjct: 361 YNFKAGYLAENGPADITIFDAKADRLVD-SHFASKAANSPFIGETLKGQVKYTICKGQIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|116627822|ref|YP_820441.1| Dihydroorotase [Streptococcus thermophilus LMD-9]
gi|116101099|gb|ABJ66245.1| Dihydroorotase [Streptococcus thermophilus LMD-9]
Length = 422
Score = 226 bits (575), Expect = 3e-57, Method: Composition-based stats.
Identities = 150/421 (35%), Positives = 224/421 (53%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+G + D+L+ K+ KI+ENID D ID V G +D HVH
Sbjct: 2 LLIKNGRVVDPKSGLDMQADVLVDGKKVVKIAENIDAGDAQVIDATGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GGFTTV+ M N NP ETL + L ++ I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTNPTISDKETLKEVLTSAAKEN-IHVKS 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
ITK G ++D + + + F+DDG + +A ++ +AM + + N I H ED
Sbjct: 121 VATITKNFDGENITDFKGLLEAGAVGFSDDGIPLTNAGIVKKAMELAKENNTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +E E I G + E + IARD+++A H H+ H+S ESV+ V
Sbjct: 181 PDLNGVLGFNENIAKKEFHICGATGVAEYSMIARDVMVAYDTQAHVHIQHLSKAESVKVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+K +VT EV P H ++ + KMNPPLR DR A+I G+ G I +I
Sbjct: 241 EFAQKLGAQVTAEVAPQHFSKTEDLLLSKGANAKMNPPLRLESDRQAVIEGLKSGVISVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH +EK + + K+ G+ G ET+ + T V+ SL L+KLM+ N + +
Sbjct: 301 ATDHAPHHADEKNVADVTKAPSGMTGLETSLSLGLTYLVEAGHLSLTELLKLMTSNPSDL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L EN AD+V+ +KE +F SK N+P+ E++ G TI +G+I
Sbjct: 361 YGFDAGYLAENGPADLVIF-ADKEKRQVTADFKSKAANSPFVGEELTGSVKYTICDGEIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|83312713|ref|YP_422977.1| Dihydroorotase and related cyclic amidohydrolase [Magnetospirillum
magneticum AMB-1]
gi|82947554|dbj|BAE52418.1| Dihydroorotase and related cyclic amidohydrolase [Magnetospirillum
magneticum AMB-1]
Length = 436
Score = 225 bits (574), Expect = 4e-57, Method: Composition-based stats.
Identities = 124/378 (32%), Positives = 200/378 (52%), Gaps = 2/378 (0%)
Query: 41 IDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVET 100
+D K + G +D V REPG KET+ +A AA GG T+++ +PN NPV D V T
Sbjct: 56 VDCKGLCLAPGLVDMRVQLREPGEEHKETLKSAGEAAVAGGVTSMVCLPNTNPVIDEVAT 115
Query: 101 LNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYE 159
+ + + + PY A TK G+EL++M +A+ FTD + +++A VM
Sbjct: 116 VEFVARRARKIGLAKVYPYAAATKRVEGKELAEMGMLAEAGALGFTDGLKAIRNAQVMRR 175
Query: 160 AMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAA 219
A+ + IV H E+ SL GG M+EG+ + +G+ GIP E+ + RD+ L E
Sbjct: 176 ALTYAATFGLLIVQHPEEPSLAEGGMMNEGELATRMGLSGIPVAAEAIMLERDMRLVEIT 235
Query: 220 NCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGR 279
N YH H++ V +R+ K + VTC+ P + + +K+ K++PPLR
Sbjct: 236 NGRYHAAHVATAAGVEIIRKAKAKGLPVTCDTAPPYFALNELAVKDYRTFAKLSPPLRSE 295
Query: 280 EDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDI 339
DR A++ G+ DGTID +A+DH+P + K + FG VG ET +
Sbjct: 296 TDRQAVVEGLKDGTIDAVASDHSPQDQDSKRVPFAVAEFGGVGLET-LLPVTLDLAHNGH 354
Query: 340 FSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYAN 399
SL ++L++ + I NL G+L+ + AD+V+ D ++ +N + F SK +N+P+ +
Sbjct: 355 MSLIEALRLITCAPSAILNLAAGRLKVGAAADLVLFDPDRGWKVNAKSFHSKSKNSPFDD 414
Query: 400 EKVNGIPVLTISNGKIAY 417
V G+ + TI +G+ Y
Sbjct: 415 RPVQGMVMRTIVDGRTVY 432
>gi|77410438|ref|ZP_00786799.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae CJB111]
gi|77163386|gb|EAO74336.1| dihydroorotase, multifunctional complex type [Streptococcus
agalactiae CJB111]
Length = 430
Score = 225 bits (574), Expect = 4e-57, Method: Composition-based stats.
Identities = 150/420 (35%), Positives = 221/420 (52%), Gaps = 12/420 (2%)
Query: 8 ILKNG-------KFKKV-DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
I+KNG F +V D+LI KI++IS+ ID+ ID ++ V G +D HVH+
Sbjct: 3 IIKNGLIIDPQSGFNQVSDMLIDQGKIKQISKEIDIKGIPIIDASNKIVAPGLVDIHVHF 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG + KE ++T + +AA GGFTTV+ M N NP S E + KQ++ I+
Sbjct: 63 REPGQTHKENIHTGALSAAAGGFTTVLMMANTNPTISSPEIV-KQVKESAAKEAIKIETV 121
Query: 120 GAITKEEYGRELSDMEDIADKVFA-FTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
ITK G++L + E++ + A F+DDG + V+ EAM + K + + H ED
Sbjct: 122 ATITKSLNGKDLVNFEELLEAGAAGFSDDGIPLTDTKVLQEAMNLARKHDVVLSLHEEDP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL ++E + G + E + IARD ++A H+ H+S+ ESV V
Sbjct: 182 SLNGVLGINEHIAQKIYHVCGASGLAEYSMIARDAMIAYQTQAKVHIQHLSSSESVEVVD 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+K +T EVTP H ++ + K+NPPLR +DR ALI G+ G I IIA
Sbjct: 242 FAQKLGANLTAEVTPQHFSKTEDLLLTKGANAKLNPPLRLEKDRQALIDGLKSGVISIIA 301
Query: 299 TDHAP-HTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
+DHAP H ME+ I ++ G+ G ET+ T V T S+ + M+ N A+++
Sbjct: 302 SDHAPHHIMEKAADNISQAPSGMTGLETSLALGITYLVSTKELSMIDFLAKMTCNPAQLY 361
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G L E ADIV+ D +E I EF SK N+P+ +K+ G+ TI NG+I Y
Sbjct: 362 GFDAGYLREGGPADIVIFDQAEERIIKA-EFASKSSNSPFIGDKLKGVVHYTICNGEIVY 420
>gi|149025521|ref|ZP_01836454.1| dihydroorotase [Streptococcus pneumoniae SP23-BS72]
gi|147929393|gb|EDK80390.1| dihydroorotase [Streptococcus pneumoniae SP23-BS72]
Length = 422
Score = 225 bits (574), Expect = 4e-57, Method: Composition-based stats.
Identities = 152/421 (36%), Positives = 222/421 (52%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+G + D+L++D KI KI+ I TID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETIDATGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GGFTTV+ M N +P VETL L+ + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEK-INVKT 120
Query: 119 YGAITKEEYGRELSDMEDIADKVFA-FTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
ITK G+ L+D + + + A F+DDG ++S+ ++ EAM K N I H ED
Sbjct: 121 VATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIVKEAMEEAKKFNTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +E I G + E +ARD+++A A H H+ H+S +ESV+ V
Sbjct: 181 PGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
+ VT EV P H + + KMNPPLR DR A+I G+ G I +I
Sbjct: 241 EFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH ++EK + I K+ G+ G ET+ + T V+ SL L++ M+ N AK+
Sbjct: 301 ATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLGLTYLVEAGELSLMELLEKMTYNPAKL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+N G L EN ADI + D + + ++ F SK N+P+ E + G TI G+I
Sbjct: 361 YNFKAGYLAENGPADITIFDAKADRLVD-SHFASKAANSPFIGETLKGQVKYTICKGQIV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|22537204|ref|NP_688055.1| dihydroorotase [Streptococcus agalactiae 2603V/R]
gi|25011131|ref|NP_735526.1| dihydroorotase [Streptococcus agalactiae NEM316]
gi|76798071|ref|ZP_00780327.1| dihydroorotase [Streptococcus agalactiae 18RS21]
gi|22534069|gb|AAM99927.1|AE014239_19 dihydroorotase, multifunctional complex type [Streptococcus
agalactiae 2603V/R]
gi|23095530|emb|CAD46739.1| Unknown [Streptococcus agalactiae NEM316]
gi|76586576|gb|EAO63078.1| dihydroorotase [Streptococcus agalactiae 18RS21]
Length = 430
Score = 225 bits (573), Expect = 4e-57, Method: Composition-based stats.
Identities = 150/420 (35%), Positives = 220/420 (52%), Gaps = 12/420 (2%)
Query: 8 ILKNG-------KFKKV-DILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHW 59
I+KNG F +V D+LI KI++IS+ ID+ ID ++ V G +D HVH+
Sbjct: 3 IIKNGLIIDPQSGFNQVSDMLIDQGKIKQISKEIDIKGIPIIDASNKIVAPGLVDIHVHF 62
Query: 60 REPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPY 119
REPG + KE ++T + +AA GGFTTV+ M N NP S E + KQ++ I+
Sbjct: 63 REPGQTHKENIHTGALSAAVGGFTTVLMMANTNPTISSPEIV-KQVKESAAKEAIKIETV 121
Query: 120 GAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDN 178
ITK G++L + E++ + V F+DDG + V+ EAM + K + + H ED
Sbjct: 122 ATITKSLNGKDLVNFEELLEAGVAGFSDDGIPLTDTKVLQEAMNLARKHDVVLSLHEEDP 181
Query: 179 SLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVR 238
SL ++E + G + E + IARD ++A H+ H+S+ ESV V
Sbjct: 182 SLNGVLGINEHIAQKIYHVCGASGLAEYSMIARDAMIAYQTQAKVHIQHLSSSESVEVVD 241
Query: 239 EGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIA 298
+K +T EVTP H + + K+NPPLR +DR ALI G+ G I IIA
Sbjct: 242 FAQKLGANLTAEVTPQHFSKTENLLLTKGANAKLNPPLRLEKDRQALIDGLKSGVISIIA 301
Query: 299 TDHAP-HTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIF 357
+DHAP H ME+ I ++ G+ G ET+ T V T S+ + M+ N A+++
Sbjct: 302 SDHAPHHIMEKAADNISQAPSGMTGLETSLALGITYLVSTKELSMIDFLAKMTCNPAQLY 361
Query: 358 NLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G L E ADIV+ D +E I EF SK N+P+ +K+ G+ TI NG+I Y
Sbjct: 362 GFDAGYLREGGPADIVIFDQAEERIIKA-EFASKSSNSPFIGDKLKGVIHYTICNGEIVY 420
>gi|71903354|ref|YP_280157.1| dihydroorotase [Streptococcus pyogenes MGAS6180]
gi|71802449|gb|AAX71802.1| dihydroorotase [Streptococcus pyogenes MGAS6180]
Length = 422
Score = 225 bits (573), Expect = 4e-57, Method: Composition-based stats.
Identities = 141/421 (33%), Positives = 228/421 (54%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + D+LI +I KI+ I+ + ID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GG TTV+ M N NPV VETL + L + I
Sbjct: 62 FREPGQTHKEDIHTGALAAASGGVTTVVMMANTNPVISDVETLQEVLASAAKEK-IHIYT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
++T+ G++++D + + + +F+DDG ++S+ V+ EA + + I H ED
Sbjct: 121 NASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +EG G + E + IARD+++A H H+ H+S ESV+ V
Sbjct: 181 PQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
++ +VT EV+P H + ++ + KMNPPLR + DR A+I G+ G I +I
Sbjct: 241 AFAQQLGAKVTAEVSPQHFSTTEDLLLIVGTSAKMNPPLRTQRDRLAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH +EK + + K+ G+ G ET+ + T V+ +L L++ M+ N A +
Sbjct: 301 ATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L EN AD+V+ ++E I E F SK N+P+ K+ G+ TI++G++
Sbjct: 361 YGFDAGYLAENGPADLVIFADKQERLIT-ENFASKASNSPFIGNKLKGVVKYTIADGEVV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|68235084|ref|ZP_00574123.1| Dihydroorotase multifunctional complex type [Frankia sp. EAN1pec]
gi|68197309|gb|EAN11642.1| Dihydroorotase multifunctional complex type [Frankia sp. EAN1pec]
Length = 451
Score = 224 bits (570), Expect = 1e-56, Method: Composition-based stats.
Identities = 134/392 (34%), Positives = 194/392 (49%), Gaps = 9/392 (2%)
Query: 41 IDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVET 100
+D G +D H H REPG ETV + +RAAA GG+TTV M N +PV D+
Sbjct: 60 VDATGLVALPGLVDLHTHLREPGREDAETVDSGTRAAALGGYTTVFAMANTDPVADTAGV 119
Query: 101 LNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADKVFA---FTDDGRGVQSANVM 157
+ + + ++ P GA+T+ G L+++ +A A F+DDG V A +M
Sbjct: 120 VEQVWRLGQDAGHCDVRPVGAVTRGLAGERLAELGAMASSAAAVRMFSDDGHCVSDALLM 179
Query: 158 YEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAE 217
A+ + I H E+ L G M+EG +A LG+ G P++ E IARD LL
Sbjct: 180 RRALEYVKAFDGVIAQHAEEPRLTAGAQMNEGAMAARLGLPGWPAVAEEAIIARDALLTG 239
Query: 218 AANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLR 277
H+CH+S SV +R K RVT EVTPHHLL +E + + ++K+NPPLR
Sbjct: 240 HVGSRLHICHVSTAGSVELIRWAKAKGWRVTAEVTPHHLLLTEELVASYDPVYKVNPPLR 299
Query: 278 GREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKT 337
D AL AG+ DGTID +ATDHAPH E+K + G++G ETA + + V+T
Sbjct: 300 TAADTEALRAGLADGTIDCVATDHAPHASEDKETEWAAARPGMLGLETALSIVIQTMVET 359
Query: 338 DIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADI------VVIDLEKEITINPEEFLSK 391
+ M+ A+I + + SFA + ++D E I+P S+
Sbjct: 360 GRLDWAGVADRMALAPARIGAVADTPRDPASFAQVGAPATLTLLDPEARRVIDPLAVASR 419
Query: 392 GRNTPYANEKVNGIPVLTISNGKIAYIDKEEI 423
NTPY + G T G+ +D + I
Sbjct: 420 SSNTPYGGRTLPGAIRATFLRGRPTVLDGKII 451
>gi|111224610|ref|YP_715404.1| Dihydroorotase (DHOase) [Frankia alni ACN14a]
gi|111152142|emb|CAJ63870.1| Dihydroorotase (DHOase) [Frankia alni ACN14a]
Length = 436
Score = 223 bits (569), Expect = 1e-56, Method: Composition-based stats.
Identities = 136/388 (35%), Positives = 192/388 (49%), Gaps = 9/388 (2%)
Query: 41 IDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVET 100
+D + G +D H H REPG ETV + +RAAA GG+TTV M N NPV D+
Sbjct: 45 LDTDGLIMLPGLVDLHTHLREPGREDAETVESGTRAAALGGYTTVFAMANTNPVADTAGV 104
Query: 101 LNKQLEIIKNDSVIRAIPYGAITKEEYGR---ELSDMEDIADKVFAFTDDGRGVQSANVM 157
+ + + + P GA+T G EL M A +V F+DDG V A +M
Sbjct: 105 VEQVWRLGLDAGHCDVRPVGAVTVGLAGERLAELGAMATSAAEVRVFSDDGHCVSDALLM 164
Query: 158 YEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAE 217
A+ + I H E+ L G M+EG +A LG+ G P++ E IARD LLA
Sbjct: 165 RRALEYVRAFDGVIAQHAEEPRLTAGAQMNEGVVAARLGLPGWPAVAEEAIIARDALLAG 224
Query: 218 AANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLR 277
HVCH+S SV +R K +VT EVTPHHLL D+ + + ++K+NPPLR
Sbjct: 225 HVGSRLHVCHVSTAGSVELIRWAKAKGWQVTAEVTPHHLLLTDDLVSSYDPVFKVNPPLR 284
Query: 278 GREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKT 337
ED AL AG+ DGTID +ATDHAPH +E+K + G++G ETA + + V
Sbjct: 285 TAEDVAALRAGLADGTIDCVATDHAPHALEDKETEWAAARPGMLGLETALSVVMETMVIP 344
Query: 338 DIFSLEMLVKLMSENVAKIFNLP------YGKLEENSFADIVVIDLEKEITINPEEFLSK 391
+ M+ A+I LP + + + A + ++D + + S+
Sbjct: 345 GHLDWAGVADRMALAPARIGGLPQPAAQRWSSIAVGAPATVTLLDPSPWRVVEADTLASR 404
Query: 392 GRNTPYANEKVNGIPVLTISNGKIAYID 419
RNTPYA + G T G+ +D
Sbjct: 405 SRNTPYAGRSLPGAIRATFLRGRPTVLD 432
>gi|86741887|ref|YP_482287.1| dihydroorotase, multifunctional complex type [Frankia sp. CcI3]
gi|86568749|gb|ABD12558.1| dihydroorotase, multifunctional complex type [Frankia sp. CcI3]
Length = 458
Score = 223 bits (568), Expect = 2e-56, Method: Composition-based stats.
Identities = 135/388 (34%), Positives = 191/388 (49%), Gaps = 9/388 (2%)
Query: 41 IDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVET 100
+D + G +D H H REPG ETV + +RAAA GG+TTV M N NPV D+
Sbjct: 67 LDTDGLILLPGLVDLHTHLREPGREDAETVASGTRAAALGGYTTVFAMANTNPVADTAGV 126
Query: 101 LNKQLEIIKNDSVIRAIPYGAITKEEYGR---ELSDMEDIADKVFAFTDDGRGVQSANVM 157
+ + + + P GA+T G EL M A V F+DDG V A +M
Sbjct: 127 VEQVWRLGLDAGHCDVRPVGAVTVGLAGERLAELGAMASSAAGVRVFSDDGHCVSDALLM 186
Query: 158 YEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAE 217
A+ + I H ++ L M+EG +A LG+ G P++ E IARD LLA
Sbjct: 187 RRALEYVKAFDGVIAQHAQEPRLTENAQMNEGTVAARLGLPGWPAVAEEAIIARDALLAG 246
Query: 218 AANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLR 277
HVCH+S SV +R K VT EVTPHHLL D+ + + ++K+NPPLR
Sbjct: 247 HVGSRLHVCHVSTAGSVEIIRWAKAKGWNVTAEVTPHHLLLTDDLVCSFDPVYKVNPPLR 306
Query: 278 GREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKT 337
ED AL AG+ DGTID +ATDHAPH +E+K + G++G ETA + + V
Sbjct: 307 TAEDVAALRAGLADGTIDCVATDHAPHALEDKETEWAAARPGMLGLETALSVVIETMVIP 366
Query: 338 DIFSLEMLVKLMSENVAKIFNLP------YGKLEENSFADIVVIDLEKEITINPEEFLSK 391
+ + M+ A+I LP + + + A + ++D + P+ S+
Sbjct: 367 GRLDWAGVAERMALAPARIGGLPRTAAEVWSSIAVGAPATVTLLDPAPWRMVEPDALASR 426
Query: 392 GRNTPYANEKVNGIPVLTISNGKIAYID 419
RNTPYA + G T G+ +D
Sbjct: 427 SRNTPYAGRSLPGTIRATFLRGRPTVLD 454
>gi|118048214|ref|ZP_01516829.1| dihydroorotase, multifunctional complex type [Chloroflexus
aggregans DSM 9485]
gi|117995282|gb|EAV09508.1| dihydroorotase, multifunctional complex type [Chloroflexus
aggregans DSM 9485]
Length = 437
Score = 221 bits (563), Expect = 7e-56, Method: Composition-based stats.
Identities = 137/412 (33%), Positives = 204/412 (49%), Gaps = 42/412 (10%)
Query: 18 DILIKDDKIEKISENIDV--------TDENTIDVKDRFVTAGFIDAHVHWREPGFSKKET 69
DIL+ D K+E++ + D+ D I+ + V GF D H H R+PG +ET
Sbjct: 22 DILVADGKVERLYDLADLHSDREPIGPDVEVINARGCVVAPGFTDLHTHLRQPGEEHRET 81
Query: 70 VYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR 129
+ + S AAA GGFTT+ P +P PD+ + + E++ + +R GA+T GR
Sbjct: 82 ITSVSAAAAVGGFTTLCARPTTHPTPDNAAAIRQLRELVAHFGSVRIDVIGALTLGNEGR 141
Query: 130 ELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
LS+M ++A+ AF+D GR + A +M A+ + LN ++ C+D SL GG HE
Sbjct: 142 ILSEMRELAEAGCIAFSDGGRTIADAALMRHALSYAAALNLPVMVTCQDPSLAAGGVAHE 201
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G S LG+ GIP+ E +ARDI LAEA H H+ +S SV +R + +RVT
Sbjct: 202 GAVSVRLGLPGIPAAAEEAIVARDIALAEATGAHLHISRVSTAGSVALIRAARARGVRVT 261
Query: 249 CEVTPHHLLSCDE----DIKEDNGM---------------W-------------KMNPPL 276
EVTPHHL D ++E N + W ++ PPL
Sbjct: 262 AEVTPHHLTLTDRWLLGWLEERNEIETGRAGAHPDLSLPSWLEPSLLPPYDSSTRVEPPL 321
Query: 277 RGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVK 336
R E AL+AG+ DG ID IA DHAP + ++ + GI G ETA T +
Sbjct: 322 RSIEHVEALVAGLRDGVIDAIAVDHAPLALVDRECEYGIAPPGISGLETALALTLTLVHR 381
Query: 337 TDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEF 388
++ + ++ KL +E A++ N L + ADIV+ D E+ ++P
Sbjct: 382 GEMDIVNLIAKL-TEGPAQVLNRSPANLRPGATADIVIFDPERSWVVDPRSL 432
>gi|146318656|ref|YP_001198368.1| dihydroorotase [Streptococcus suis 05ZYH33]
gi|146320862|ref|YP_001200573.1| dihydroorotase [Streptococcus suis 98HAH33]
gi|145689462|gb|ABP89968.1| dihydroorotase [Streptococcus suis 05ZYH33]
gi|145691668|gb|ABP92173.1| dihydroorotase [Streptococcus suis 98HAH33]
Length = 423
Score = 219 bits (559), Expect = 2e-55, Method: Composition-based stats.
Identities = 142/422 (33%), Positives = 226/422 (53%), Gaps = 7/422 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENI-DVTDENTIDVKDRFVTAGFIDAHV 57
+L+KN ++L ++G K DIL+ KI KI+E+I + ++ ID V G +D HV
Sbjct: 2 LLVKNGRVLDPQSGLDKVCDILMDGSKIVKIAESISEDVEQEVIDATGLVVAPGLVDVHV 61
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
H+REPG + KE ++T + +AA GGFT+V+ M N +P ++ETL + L+ K ++ I
Sbjct: 62 HFREPGQTHKEDIHTGALSAAAGGFTSVVMMANTSPTISNIETLKEVLDSAKKEA-IHIY 120
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
IT G+ L+D + + AF+DDG + +A V+ +AM + + I H E
Sbjct: 121 SVATITDHFDGQNLTDFPALLEAGAVAFSDDGIPLTNAGVVRKAMKLAKEQGCLISLHEE 180
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D L ++E + G + E + +ARD+++A H+ H+S ESV+
Sbjct: 181 DPDLNGVLGLNEQVAEKHFHVCGATGVAEYSMVARDVMIAYETGARVHIQHLSKAESVKV 240
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
V + VT EV P H +E + KMNPPLR DR A+I G+ G I +
Sbjct: 241 VEFVQGLGANVTAEVAPQHFSRTEELLLTKGANAKMNPPLRLESDRLAVIDGLKSGVISV 300
Query: 297 IATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IATDHAPH +EK + + ++ G+ G ET+ + T V+ +L L++ M+ N AK
Sbjct: 301 IATDHAPHHPDEKNVEDLTQAPSGMTGLETSLSLGLTHLVEEGHLTLVQLLEKMTINPAK 360
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
++ L G L EN AD+V+ D + +F SK N+P+ + + G + TI+NG+I
Sbjct: 361 LYGLDAGYLAENGPADLVIFDPNANRLVTA-DFASKSANSPFVGDSLKGQVLYTIANGQI 419
Query: 416 AY 417
+
Sbjct: 420 VF 421
>gi|153938072|ref|YP_001392590.1| dihydroorotase, multifunctional complex type [Clostridium botulinum
F str. Langeland]
gi|152933968|gb|ABS39466.1| dihydroorotase, multifunctional complex type [Clostridium botulinum
F str. Langeland]
Length = 396
Score = 219 bits (558), Expect = 2e-55, Method: Composition-based stats.
Identities = 137/417 (32%), Positives = 224/417 (53%), Gaps = 27/417 (6%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN I+ + D+ IK+ IE++ ++++ E D + + FID H H+R
Sbjct: 4 LLIKNVNIIDWCQNFHGDVYIKNGIIEELGKDLNKNCE-IFDGRGLTLLPSFIDMHAHFR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
+PGF+ KE + T SRAA +GG+T V M N P+ S + + LE K ++
Sbjct: 63 DPGFTYKEDILTGSRAAVKGGYTMVNLMANTKPICSSNKEVEYVLEKGKEIGLVDIHQCM 122
Query: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
+ITK+ G ++S ++ I KV ++DG+ V + V+ EAM + + ++ H E++ +
Sbjct: 123 SITKDFSGDDISHLDSIDKKVKIISEDGKDVMNTRVLIEAMFKAKEKDLIVMCHSEEHDV 182
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
+ E+ R+I L+E +C H+ H+S KES+ +++
Sbjct: 183 TNLDT----------------RLSENLMTWRNIALSEFTDCKVHIAHVSTKESMEYIKDA 226
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
KK ++VTCEV PHH+ ++ +++NPPLR ED LI + + +D I TD
Sbjct: 227 KKKGLKVTCEVAPHHIALTNKI------FYRVNPPLREEEDIKVLIEAIKEDLVDCIGTD 280
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPH+ E+K++G S GI G ET+F+ YTK V + SL L K+MS+N A I +
Sbjct: 281 HAPHSKEDKLKG----SPGISGIETSFSTCYTKLVHNNHISLSKLSKIMSKNPADILGVN 336
Query: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+++ AD+V++D ++E + EEF SKG+NTP + G +T G I Y
Sbjct: 337 KGEIKIGREADLVLVDTKEEYKVKSEEFHSKGKNTPMDGMCLKGRVKVTFKAGCIVY 393
>gi|148381188|ref|YP_001255729.1| dihydroorotase [Clostridium botulinum A str. ATCC 3502]
gi|153932193|ref|YP_001385563.1| dihydroorotase, multifunctional complex type [Clostridium botulinum
A str. ATCC 19397]
gi|153936661|ref|YP_001388969.1| dihydroorotase, multifunctional complex type [Clostridium botulinum
A str. Hall]
gi|148290672|emb|CAL84801.1| dihydroorotase [Clostridium botulinum A str. ATCC 3502]
gi|152928237|gb|ABS33737.1| dihydroorotase, multifunctional complex type [Clostridium botulinum
A str. ATCC 19397]
gi|152932575|gb|ABS38074.1| dihydroorotase, multifunctional complex type [Clostridium botulinum
A str. Hall]
Length = 396
Score = 219 bits (557), Expect = 4e-55, Method: Composition-based stats.
Identities = 137/417 (32%), Positives = 223/417 (53%), Gaps = 27/417 (6%)
Query: 1 MLLKNCKILKNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWR 60
+L+KN I+ + D+ IK+ IE++ ++++ E D + + FID H H+R
Sbjct: 4 LLIKNVNIIDWCQNFHGDVYIKNGIIEELGKDLNKNCE-IFDGRGLTLLPSFIDMHAHFR 62
Query: 61 EPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYG 120
+PGF+ KE + T SRAA +GG+T V M N P+ S + + LE K ++
Sbjct: 63 DPGFTYKEDILTGSRAAVKGGYTMVNLMANTKPICSSNKEVEYVLEKGKEIGLVDIHQCM 122
Query: 121 AITKEEYGRELSDMEDIADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSL 180
+ITK+ G ++S ++ I KV ++DG+ V + V+ EAM + + ++ H E++ +
Sbjct: 123 SITKDFSGDDISHLDSIDKKVKIISEDGKDVMNTRVLIEAMFKAKEKDLIVMCHSEEHDV 182
Query: 181 IRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREG 240
+ E+ R+I L+E +C H+ H+S KES+ ++
Sbjct: 183 TNLDT----------------RLSENLMTWRNIALSEFTDCKVHIAHVSTKESMEYIKNA 226
Query: 241 KKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATD 300
KK ++VTCEV PHH+ ++ +++NPPLR ED LI + + +D I TD
Sbjct: 227 KKKGLKVTCEVAPHHIALTNKI------FYRVNPPLREEEDIKVLIEAIKEDLVDCIGTD 280
Query: 301 HAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLP 360
HAPH+ E+K++G S GI G ET+F+ YTK V + SL L K+MS+N A I +
Sbjct: 281 HAPHSKEDKLKG----SPGISGIETSFSTCYTKLVHNNHISLSKLSKIMSKNPADILGVN 336
Query: 361 YGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
G+++ AD+V++D ++E + EEF SKG+NTP + G +T G I Y
Sbjct: 337 NGEIKIGREADLVLVDTKEEYKVKSEEFHSKGKNTPMDGMYLKGRIKVTFKAGCIVY 393
>gi|28493334|ref|NP_787495.1| dihydroorotase [Tropheryma whipplei str. Twist]
gi|28476375|gb|AAO44464.1| dihydroorotase [Tropheryma whipplei str. Twist]
Length = 428
Score = 219 bits (557), Expect = 4e-55, Method: Composition-based stats.
Identities = 132/390 (33%), Positives = 206/390 (52%), Gaps = 9/390 (2%)
Query: 30 SENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMP 89
++N D ID + G +D H H R S+ ++ + AA GG+TTV +MP
Sbjct: 44 TKNTDKASCRVIDAEGFIALPGLVDLHTHLRN---SRDGSIRDVTSAAIAGGYTTVSSMP 100
Query: 90 NLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDG 148
N++PV DS E +N I K D+V P GA+TK G E++DM + D V F+DDG
Sbjct: 101 NMHPVQDSPEAVNILKAIAKEDAVCDIRPVGAVTKGLRGNEITDMHSLLDAGVNIFSDDG 160
Query: 149 RGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGI-PSICEST 207
V +M++A+ + N I H +D +L + + + + K + PSI EST
Sbjct: 161 NCVHDPGIMHQALSFAGRNNCVIAQHAQDPTLTK--SAQGDTQGPIVAPKSLWPSIAEST 218
Query: 208 QIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDN 267
+ARDILLA AAN HVCH+S++ESV A+ GK ++VT EVTPHHLL D + +
Sbjct: 219 IVARDILLARAANARLHVCHVSSQESVYAIAWGKSLGVQVTAEVTPHHLLFYDSLVMTGD 278
Query: 268 GMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAF 327
+K+NPPLR +E L ++ G ID++ATDHAPH K + G+ G E +
Sbjct: 279 TRFKVNPPLRSKESVECLRDALIRGVIDVVATDHAPH--RNKSPFWHSAPNGMTGLEFSV 336
Query: 328 TQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEE 387
+ + FV + + +V++MS A+I + ++E S A+ + + + + ++
Sbjct: 337 SVIQKIFVNSGHLTWPEVVRIMSNKPAEILGMTPNTVKEGSAANFFLYNPDVTRFVTFDD 396
Query: 388 FLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L N+PYA + G + T G++ +
Sbjct: 397 SLGPSVNSPYAGMNLPGKVMYTFYEGRLVF 426
>gi|144898212|emb|CAM75076.1| Dihydroorotase multifunctional complex type [Magnetospirillum
gryphiswaldense MSR-1]
Length = 434
Score = 218 bits (555), Expect = 6e-55, Method: Composition-based stats.
Identities = 121/378 (32%), Positives = 198/378 (52%), Gaps = 2/378 (0%)
Query: 41 IDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVET 100
+D + + G +D V REPG KET+ +A AA GG T+++ +PN +P+ D V T
Sbjct: 56 VDCQGLCLAPGLVDMRVQVREPGEEHKETLKSAGEAAVAGGVTSMVCLPNTDPIMDEVAT 115
Query: 101 LNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYE 159
+ + + + + PY A TK+ G+ELS+M + + AFTD + + A M
Sbjct: 116 VEFVARRARKNGLAKIYPYAAATKKLEGKELSEMGFLKEAGALAFTDGIKAIADAQTMRR 175
Query: 160 AMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAA 219
A+ + + IV H ED SL G M+ G+R+ +G+ GIP E + RD+ L
Sbjct: 176 ALSYAATFDALIVQHPEDPSLAGSGVMNAGERATRMGLSGIPVEAEIIMLERDMRLVAMT 235
Query: 220 NCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGR 279
YH H+S E + +R K + VTC+ P + + ++ K++PPLR
Sbjct: 236 GGRYHAAHVSTAEGIDVIRRAKAKGLPVTCDTAPPYFALNELEVHNYRTFAKLSPPLRSE 295
Query: 280 EDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDI 339
DR A+IAG+ DGTID IA+DHAP + K + + FG +G ET V+T
Sbjct: 296 ADRQAVIAGLADGTIDAIASDHAPQDEDAKRQTFAAAEFGGIGLETLLAAT-IGLVQTGA 354
Query: 340 FSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYAN 399
+L + L++ A I LP G+L+ + AD+V+ D ++ ++P +F SK +N+P+
Sbjct: 355 LALLPALGLLTCGPADILALPAGRLKMGAAADLVLFDPDRGWQVDPVKFKSKSKNSPFDG 414
Query: 400 EKVNGIPVLTISNGKIAY 417
+ G+ + T+ +G+ +
Sbjct: 415 RPMQGVVLRTVVDGRTVH 432
>gi|28572555|ref|NP_789335.1| dihydroorotase [Tropheryma whipplei TW08/27]
gi|28410687|emb|CAD67073.1| dihydroorotase [Tropheryma whipplei TW08/27]
Length = 428
Score = 216 bits (551), Expect = 2e-54, Method: Composition-based stats.
Identities = 131/390 (33%), Positives = 206/390 (52%), Gaps = 9/390 (2%)
Query: 30 SENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRAAARGGFTTVMTMP 89
++N D ID + G +D H H R S+ ++ + AA GG+TTV +MP
Sbjct: 44 TKNTDKASCRVIDAEGFIALPGLVDLHTHLRN---SRDGSIRDVTSAAIAGGYTTVSSMP 100
Query: 90 NLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMEDIADK-VFAFTDDG 148
N++PV DS E +N I K D+V P GA+TK G E++DM + D V F+DDG
Sbjct: 101 NMHPVQDSPEAVNILKAIAKEDAVCDIRPVGAVTKGLRGNEITDMHSLLDAGVNIFSDDG 160
Query: 149 RGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGI-PSICEST 207
V ++++A+ + N I H +D +L + + + + K + PSI EST
Sbjct: 161 NCVYDPGIIHQALSFAGRNNCVIAQHAQDPTLTK--SAQGDTQGPIVAPKSLWPSIAEST 218
Query: 208 QIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDN 267
+ARDILLA AAN HVCH+S++ESV A+ GK ++VT EVTPHHLL D + +
Sbjct: 219 IVARDILLARAANARLHVCHVSSQESVYAIAWGKSLGVQVTAEVTPHHLLFYDSLVMTGD 278
Query: 268 GMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAF 327
+K+NPPLR +E L ++ G ID++ATDHAPH K + G+ G E +
Sbjct: 279 TRFKVNPPLRSKESVECLRDALIRGVIDVVATDHAPH--RNKSPFWHSAPNGMTGLEFSV 336
Query: 328 TQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVIDLEKEITINPEE 387
+ + FV + + +V++MS A+I + ++E S A+ + + + + ++
Sbjct: 337 SVIQKIFVNSGHLTWPEVVRIMSNKPAEILGMTPNTVKEGSAANFFLYNPDVTRFVTFDD 396
Query: 388 FLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
L N+PYA + G + T G++ +
Sbjct: 397 SLGPSVNSPYAGMNLPGKVMYTFYEGRLVF 426
>gi|24379638|ref|NP_721593.1| dihydroorotase [Streptococcus mutans UA159]
gi|24377591|gb|AAN58899.1|AE014958_3 putative dihydroorotase [Streptococcus mutans UA159]
Length = 422
Score = 216 bits (550), Expect = 2e-54, Method: Composition-based stats.
Identities = 148/422 (35%), Positives = 224/422 (53%), Gaps = 8/422 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN ++L K+G + +D+L+ K+ KI+ENI+ D ID + V G +D HVH
Sbjct: 2 LLIKNGRVLDPKSGLDRVLDVLLDGKKVVKIAENIESVDAQVIDAEGLVVAPGLVDVHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSV-IRAI 117
+REPG + KE ++T + AAA GG TTV+ M N P V TL + LE +++ I+ +
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGVTTVVMMANTTPTISDVATLTEVLESAAKENIHIKTV 121
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
ITK G+ L+D E + F+DDG + S+ V+ EA+ + K + I H E
Sbjct: 122 --ATITKHFDGQHLTDFETLLKAGAVGFSDDGIPLTSSKVVKEALDLAKKNDTFISLHEE 179
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D L +E I G + E + IARD+++A H H+ H+S ESV+
Sbjct: 180 DPELNGILGFNEKIAKEHFKICGATGVAEYSMIARDVMIAYDRQAHIHIQHLSKAESVKV 239
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
V +K +VT E P H + + E KMNPPLR DR A+I G+ G I +
Sbjct: 240 VAFAQKLGAQVTAEAAPQHFSKTENLLLEKGANAKMNPPLRLEADRLAVIEGLKSGVISV 299
Query: 297 IATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IATDHAPH +EK + + K+ G+ G ET+ + T V+ SL + M+ N A+
Sbjct: 300 IATDHAPHHADEKNVADVTKAPSGMTGLETSLSLGLTYLVEAGHLSLMDFLAKMTINPAQ 359
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
+++ G L EN AD+V+ +KE + F SK N+P+ E + G TI +G++
Sbjct: 360 LYDFDVGYLAENGPADLVIF-ADKEDRLVSNHFASKAANSPFIGETLKGQVKYTICSGEV 418
Query: 416 AY 417
Y
Sbjct: 419 IY 420
>gi|117923420|ref|YP_864037.1| dihydroorotase, multifunctional complex type [Magnetococcus sp.
MC-1]
gi|117607176|gb|ABK42631.1| dihydroorotase, multifunctional complex type [Magnetococcus sp.
MC-1]
Length = 428
Score = 216 bits (549), Expect = 3e-54, Method: Composition-based stats.
Identities = 136/409 (33%), Positives = 213/409 (52%), Gaps = 4/409 (0%)
Query: 11 NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTA-GFIDAHVHWREPGFSKKET 69
N + + DILI D I +I + +D + D + A G +D HVH REPG+ KET
Sbjct: 19 NERDEIADILIVDGVIREIGK-LDAPAHVPVIEADGLIAAPGLVDMHVHLREPGYEYKET 77
Query: 70 VYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGR 129
+ +RAAA GG T+V MPN PV D L+ + P GA++K G+
Sbjct: 78 IAGGTRAAAAGGVTSVAAMPNTKPVNDDPSVTGYMLDKARVAGFANLFPIGAVSKGLQGK 137
Query: 130 ELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHE 188
E+++M + A AF+DDG + ++ +M A+ I+ H ED+ L+ G M+E
Sbjct: 138 EITEMGLLQAAGCVAFSDDGLPIMNSGLMRRALDYSRAFGGLIIQHAEDSGLVGCGCMNE 197
Query: 189 GKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVT 248
G+ + LG+ GI + E + RDI L E YHV HIS+ +V +V + ++ +RV+
Sbjct: 198 GEVATRLGLSGICNAAEDILVERDIRLVELTGGRYHVAHISSAGAVASVAKAREKGLRVS 257
Query: 249 CEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEE 308
CE PHHL+ D + + KM PPLR + D NA+ + G I +IATDHAPH +
Sbjct: 258 CEAAPHHLVLNDTHVGNYDTNAKMAPPLRNQRDVNAIQEALARGVISVIATDHAPHEEDS 317
Query: 309 KIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENS 368
K +++ G+VG ET + + V+ + L + +S N A++ +P G L N+
Sbjct: 318 KRVPFCQAANGVVGLET-LLPITLELVEAGVLPLAKALAAISCNPARLLGMPRGTLSLNA 376
Query: 369 FADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
D+V+ D ++ T++ +NT +A +V G TI G+I +
Sbjct: 377 VGDVVLFDPQQSWTVDALALHGSSKNTAFAGRQVKGRVKYTILAGRIVH 425
>gi|154487393|ref|ZP_02028800.1| hypothetical protein BIFADO_01245 [Bifidobacterium adolescentis
L2-32]
gi|154083911|gb|EDN82956.1| hypothetical protein BIFADO_01245 [Bifidobacterium adolescentis
L2-32]
Length = 472
Score = 215 bits (548), Expect = 4e-54, Method: Composition-based stats.
Identities = 149/474 (31%), Positives = 229/474 (48%), Gaps = 74/474 (15%)
Query: 19 ILIKDDKIEKISENIDVT----DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTAS 74
+ + D K+ E ID+ + ++D + GF D HVH+R+PG + KE++ +
Sbjct: 3 LTLHDIKVWNTGEVIDLVVPSDTDASVDASAMTIAPGFEDPHVHFRDPGQTYKESMISGC 62
Query: 75 RAAARGGFTTVMTMPNLNPVPDSVETLNKQ---LEII--KNDSVIRAIPY---------- 119
AAA GG+T V+ MPN P D V+ Q E++ + D+VI + +
Sbjct: 63 AAAASGGYTNVLIMPNTVPAMDGVKVEAGQPGASEVLDAEYDTVIDYLQHYEAAHGVKLP 122
Query: 120 -----------GAITKE------------EYGRELSDMEDIADKVFAFTDDGRGVQSANV 156
G E E+G E D +A V A +DDG V + ++
Sbjct: 123 VRYDLCVCASKGRAGHEATEVADWIGYLPEHGDEHKDAYQLAHPVTAISDDGSAV-TPSI 181
Query: 157 MYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLA 216
+ + + ++ HCE + GA+++G S +LG+ GIP E + RDI ++
Sbjct: 182 LEQVFENVKESGLYLIEHCEHHDT---GAVNDGPVSRKLGVPGIPEDTELKIVERDIDMS 238
Query: 217 EAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPL 276
H H H+S S A+R+ K + +TCE PH++ DE + + + KMNPPL
Sbjct: 239 RKTGVHVHFQHVSTAISFDAIRKAKAEGLPITCETAPHYIALNDEALLKYGTLAKMNPPL 298
Query: 277 RGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVK 336
R DR A IA V DGT+D++ATDHAPHTMEEK G + GI+G E A+ + V
Sbjct: 299 RSEADRQATIAAVADGTVDLLATDHAPHTMEEKELGFLDAPNGIIGLECAYGVCHKVLVD 358
Query: 337 TDIFSLEMLVKLMSENVAKIFN--------------------------LPYGKLEENSFA 370
S E L++LMS A++ L G++ E+
Sbjct: 359 GGFISDERLIELMSTGPAELMGHDKTDITAVLDDYADAVPGDDDTKRVLDLGRVPESDQV 418
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY--IDKEE 422
D+VV++ +E T++PE+F S RNTP+ +V G P+ TI K+A+ IDKE+
Sbjct: 419 DLVVLNTGEEWTVDPEKFHSSARNTPFGGWQVTGRPLATIIGSKLAFSRIDKED 472
>gi|157076146|gb|ABV10829.1| dihydroorotase [Streptococcus gordonii str. Challis substr. CH1]
Length = 422
Score = 215 bits (547), Expect = 5e-54, Method: Composition-based stats.
Identities = 143/422 (33%), Positives = 228/422 (54%), Gaps = 8/422 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K G + D+L++ KI KI +++ ID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKTGFNQIADLLVEGKKIVKIGQDLQAEGAKVIDASGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSV-IRAI 117
+REPG + KE ++T + AAA GGFTTV+ M N NP +VETL + LE +++ I+++
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTNPTISTVETLKEVLESASRENIHIKSV 121
Query: 118 PYGAITKEEYGRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
IT+ G+ L+D + + A F+DDG + +A ++ +A++ K + I H E
Sbjct: 122 --ATITENFDGQHLTDFQGLLAAGAVGFSDDGIPLTNAGIVRQALVEARKNDTFISLHEE 179
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D +L +E I G + E + IARD+++A A H H+ H+S ESV+
Sbjct: 180 DPNLNGILGFNEHIAKEHFHICGATGVAEYSMIARDVMIAYDAKAHVHIQHLSKAESVKV 239
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
V +K +VT E P H + + KMNPPLR DR A+I G+ G I +
Sbjct: 240 VEFAQKLGAQVTAEAAPQHFSKTEALLLTKGSNAKMNPPLRLESDRLAVIEGLKSGVISV 299
Query: 297 IATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IATDHAPH +EK + I K+ G+ G ET+ + T V+ SL L++ M+ N A+
Sbjct: 300 IATDHAPHHADEKNVEDITKAPSGMTGLETSLSLGLTYLVEAGHLSLMELLEKMTVNPAR 359
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
++ G + ++ AD+ + D E E + + F SK N+P+ EK+ G TI +G++
Sbjct: 360 LYGFDAGFIAQDGPADLTIFDPE-ESRLVTDHFASKAANSPFVGEKLKGQVKYTICDGEV 418
Query: 416 AY 417
+
Sbjct: 419 VF 420
>gi|119025779|ref|YP_909624.1| dihydroorotase [Bifidobacterium adolescentis ATCC 15703]
gi|118765363|dbj|BAF39542.1| dihydroorotase [Bifidobacterium adolescentis ATCC 15703]
Length = 472
Score = 215 bits (547), Expect = 5e-54, Method: Composition-based stats.
Identities = 149/474 (31%), Positives = 229/474 (48%), Gaps = 74/474 (15%)
Query: 19 ILIKDDKIEKISENIDVT----DENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTAS 74
+ + D K+ E ID+ + ++D + GF D HVH+R+PG + KE++ +
Sbjct: 3 LTLHDIKVWNTGEVIDLVVPSDTDASVDASAMTIAPGFEDPHVHFRDPGQTYKESMISGC 62
Query: 75 RAAARGGFTTVMTMPNLNPVPDSVETLNKQ---LEII--KNDSVIRAIPY---------- 119
AAA GG+T V+ MPN P D V+ Q E++ + D+VI + +
Sbjct: 63 AAAASGGYTNVLIMPNTVPAMDGVKVEAGQPGASEVLDAEYDTVIDYLQHYEAAHGVKLP 122
Query: 120 -----------GAITKE------------EYGRELSDMEDIADKVFAFTDDGRGVQSANV 156
G E E+G E D +A V A +DDG V + ++
Sbjct: 123 VRYDLCVCASKGRAGHEATEVADWIGYLPEHGDEHKDAYQLAHPVTAISDDGSAV-TPSI 181
Query: 157 MYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLA 216
+ + + ++ HCE + GA+++G S +LG+ GIP E + RDI ++
Sbjct: 182 LEQVFENVKESGLYLIEHCEHHDT---GAVNDGPVSRKLGVPGIPEDTELKIVERDIDMS 238
Query: 217 EAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPL 276
H H H+S S A+R+ K + +TCE PH++ DE + + + KMNPPL
Sbjct: 239 RKTGVHVHFQHVSTAISFDAIRKAKAEGLPITCETAPHYIALNDEALLKYGTLAKMNPPL 298
Query: 277 RGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVK 336
R DR A IA V DGT+D++ATDHAPHTMEEK G + GI+G E A+ + V
Sbjct: 299 RSEADRQATIAAVADGTVDLLATDHAPHTMEEKELGFLDAPNGIIGLECAYGVCHKILVD 358
Query: 337 TDIFSLEMLVKLMSENVAKIFN--------------------------LPYGKLEENSFA 370
S E L++LMS A++ L G++ E+
Sbjct: 359 GGFISDERLIELMSTGPAELMGHDKTDITAVLDDYADAVPGDDDTKRVLDLGRVPESDQV 418
Query: 371 DIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY--IDKEE 422
D+VV++ +E T++PE+F S RNTP+ +V G P+ TI K+A+ IDKE+
Sbjct: 419 DLVVLNTGEEWTVDPEKFHSSARNTPFGGWQVTGRPLATIIGSKLAFSRIDKED 472
>gi|94994197|ref|YP_602295.1| Dihydroorotase [Streptococcus pyogenes MGAS10750]
gi|94547705|gb|ABF37751.1| Dihydroorotase [Streptococcus pyogenes MGAS10750]
Length = 422
Score = 215 bits (547), Expect = 5e-54, Method: Composition-based stats.
Identities = 141/421 (33%), Positives = 229/421 (54%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + D+LI +I KI+ I+ + ID V G +D HVH
Sbjct: 2 ILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GG TTV+ M N NPV VETL + L + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEK-IHIYT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
++T+ G++++D + + + +F+DDG ++S+ V+ EA + + I H ED
Sbjct: 121 NASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +EG G + E + IARD+++A H H+ H+S ESV+ V
Sbjct: 181 PQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
++ +VT EV+P H + ++ + KMNPPLR + DR A+I G+ G I +I
Sbjct: 241 AFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH +EK + + K+ G+ G ET+ + T V+ +L L++ M+ N A +
Sbjct: 301 ATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L EN AD+V+ ++E I E F+SK N+P+ K+ G+ TI++G++
Sbjct: 361 YGFDAGYLAENGPADLVIFADKQERLIT-ENFVSKASNSPFIGNKLKGVVKYTIADGEVV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|139473933|ref|YP_001128649.1| putative dihydroorotase [Streptococcus pyogenes str. Manfredo]
gi|134272180|emb|CAM30425.1| putative dihydroorotase [Streptococcus pyogenes str. Manfredo]
Length = 422
Score = 214 bits (546), Expect = 6e-54, Method: Composition-based stats.
Identities = 141/421 (33%), Positives = 229/421 (54%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + D+LI +I KI+ I+ + ID V G +D HVH
Sbjct: 2 ILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GG TTV+ M N NPV VETL + L + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEK-IHIYT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
++T+ G++++D + + + +F+DDG ++S+ V+ EA + + I H ED
Sbjct: 121 NASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLEEAFDLANANQTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +EG G + E + IARD+++A H H+ H+S ESV+ V
Sbjct: 181 PQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
++ +VT EV+P H + ++ + KMNPPLR + DR A+I G+ G I +I
Sbjct: 241 AFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH +EK + + K+ G+ G ET+ + T V+ +L L++ M+ N A +
Sbjct: 301 ATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L EN AD+V+ ++E I E F+SK N+P+ K+ G+ TI++G++
Sbjct: 361 YGFDAGYLAENGPADLVIFADKQERLIT-ENFVSKASNSPFIGNKLKGVVKYTIADGEVV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|125718055|ref|YP_001035188.1| Dihydroorotase, putative [Streptococcus sanguinis SK36]
gi|125497972|gb|ABN44638.1| Dihydroorotase, putative [Streptococcus sanguinis SK36]
Length = 422
Score = 214 bits (545), Expect = 9e-54, Method: Composition-based stats.
Identities = 141/422 (33%), Positives = 229/422 (54%), Gaps = 8/422 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K G + D+L++ KI KI +++ V D ID V G +D HVH
Sbjct: 2 LLIKNGRVMDPKTGFDQIADLLVEGKKIIKIGQDLQVKDAKVIDASGLVVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSV-IRAI 117
+REPG + KE ++T + AAA GGFTTV+ M N NP +VETL + LE +++ I+++
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGFTTVVMMANTNPAISTVETLKEVLESASRENIHIKSV 121
Query: 118 PYGAITKEEYGRELSDMED-IADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
IT+ G+ L+D + +A F+DDG + +A ++ +A++ K + I H E
Sbjct: 122 --ATITENFDGQHLTDFQGLLAAGAVGFSDDGIPLTNAGIVRQALVEARKNDTFISLHEE 179
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
D +L +E I G + E + IARD+++A A H H+ H+S ESV+
Sbjct: 180 DPNLNGILGFNEHIAKEHFHICGATGVAEYSMIARDVMIAFDAKAHVHIQHLSKSESVKV 239
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
V + +VT E P H + + KMNPPLR DR ++I G+ G I +
Sbjct: 240 VEFAQMLGAQVTAEAAPQHFSKTEALLLTKGSNAKMNPPLRLESDRLSVIEGLKSGIISV 299
Query: 297 IATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAK 355
IATDHAPH +EK + I ++ G+ G ET+ + T V+ SL L++ M+ N A+
Sbjct: 300 IATDHAPHHADEKNVADITQAPSGMTGLETSLSLGLTYLVEAGHLSLMELLEKMTFNPAQ 359
Query: 356 IFNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKI 415
++ G + ++ AD+ + D E + + + F SK N+P+ EK+ G TI +G++
Sbjct: 360 LYGFDAGFIAQDGPADLTIFDPEADRLVT-DHFASKAANSPFVGEKLKGQVKFTICDGEV 418
Query: 416 AY 417
+
Sbjct: 419 VF 420
>gi|19745971|ref|NP_607107.1| dihydroorotase [Streptococcus pyogenes MGAS8232]
gi|21910158|ref|NP_664426.1| dihydroorotase [Streptococcus pyogenes MGAS315]
gi|28896143|ref|NP_802493.1| dihydroorotase [Streptococcus pyogenes SSI-1]
gi|50914072|ref|YP_060044.1| dihydroorotase [Streptococcus pyogenes MGAS10394]
gi|94988396|ref|YP_596497.1| dihydroorotase [Streptococcus pyogenes MGAS9429]
gi|94992278|ref|YP_600377.1| Dihydroorotase [Streptococcus pyogenes MGAS2096]
gi|73621431|sp|Q8P1B5|PYRC_STRP3 Dihydroorotase (DHOase)
gi|73621432|sp|Q5XCK2|PYRC_STRP6 Dihydroorotase (DHOase)
gi|73621433|sp|Q7CNB0|PYRC_STRP8 Dihydroorotase (DHOase)
gi|19748131|gb|AAL97606.1| putative dihydroorotase [Streptococcus pyogenes MGAS8232]
gi|21904351|gb|AAM79229.1| putative dihydroorotase [Streptococcus pyogenes MGAS315]
gi|28811393|dbj|BAC64326.1| putative dihydroorotase [Streptococcus pyogenes SSI-1]
gi|50903146|gb|AAT86861.1| Dihydroorotase [Streptococcus pyogenes MGAS10394]
gi|94541904|gb|ABF31953.1| dihydroorotase [Streptococcus pyogenes MGAS9429]
gi|94545786|gb|ABF35833.1| Dihydroorotase [Streptococcus pyogenes MGAS2096]
Length = 422
Score = 214 bits (545), Expect = 1e-53, Method: Composition-based stats.
Identities = 141/421 (33%), Positives = 228/421 (54%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + D+LI +I KI+ I+ + ID V G +D HVH
Sbjct: 2 ILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GG TTV+ M N NPV VETL + L + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEK-IHIYT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
++T+ G++++D + + + +F+DDG ++S+ V+ EA + + I H ED
Sbjct: 121 NASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +EG G + E + IARD+++A H H+ H+S ESV+ V
Sbjct: 181 PQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
++ +VT EV+P H + ++ + KMNPPLR + DR A+I G+ G I +I
Sbjct: 241 AFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH +EK + + K+ G+ G ET+ + T V+ +L L++ M+ N A +
Sbjct: 301 ATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L EN AD+V+ ++E I E F SK N+P+ K+ G+ TI++G++
Sbjct: 361 YGFDAGYLAENGPADLVIFADKQERLIT-ENFASKASNSPFIGNKLKGVVKYTIADGEVV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|94990276|ref|YP_598376.1| Dihydroorotase [Streptococcus pyogenes MGAS10270]
gi|94543784|gb|ABF33832.1| Dihydroorotase [Streptococcus pyogenes MGAS10270]
Length = 422
Score = 213 bits (543), Expect = 1e-53, Method: Composition-based stats.
Identities = 141/421 (33%), Positives = 227/421 (53%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + D+LI +I KI+ I+ + ID V G +D HVH
Sbjct: 2 ILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GG TTV+ M N NPV VETL + L + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEK-IHIYT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
++T+ G++++D + + + +F+DDG ++S+ V+ EA + + I H ED
Sbjct: 121 NASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +EG G + E + IARD+++A H H+ H+S ESV V
Sbjct: 181 PQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVEVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
++ +VT EV+P H + ++ + KMNPPLR + DR A+I G+ G I +I
Sbjct: 241 AFAQRLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH +EK + + K+ G+ G ET+ + T V+ +L L++ M+ N A +
Sbjct: 301 ATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L EN AD+V+ ++E I E F SK N+P+ K+ G+ TI++G++
Sbjct: 361 YGFDAGYLAENGPADLVIFADKQERLIT-ENFASKASNSPFIGNKLKGVVKYTIADGEVV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|71910522|ref|YP_282072.1| dihydroorotase [Streptococcus pyogenes MGAS5005]
gi|71853304|gb|AAZ51327.1| dihydroorotase [Streptococcus pyogenes MGAS5005]
Length = 422
Score = 213 bits (542), Expect = 2e-53, Method: Composition-based stats.
Identities = 141/421 (33%), Positives = 228/421 (54%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + D+LI +I KI+ I+ + ID V G +D HVH
Sbjct: 2 ILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GG TTV+ M N NPV VETL + L + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEK-IHIYT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
++T+ G++++D + + + +F+DDG ++S+ V+ EA + + I H ED
Sbjct: 121 NASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +EG G + E + IARD+++A H H+ H+S ESV+ V
Sbjct: 181 PQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
++ +VT EV+P H + ++ + KMNPPLR + DR A+I G+ G I +I
Sbjct: 241 AFAQQLGAKVTAEVSPQHFSTTEDLLLIAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH +EK + + K+ G+ G ET+ + T V+ +L L++ M+ N A +
Sbjct: 301 ATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L EN AD+V+ ++E I E F SK N+P+ K+ G+ TI++G++
Sbjct: 361 YGFDAGYLAENGPADLVIFADKQERLIT-ENFASKASNSPFIGNKLKGVVKYTIADGEVV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|15674928|ref|NP_269102.1| dihydroorotase [Streptococcus pyogenes M1 GAS]
gi|73621435|sp|Q9A071|PYRC_STRP1 Dihydroorotase (DHOase)
gi|13622070|gb|AAK33823.1| putative dihydroorotase [Streptococcus pyogenes M1 GAS]
Length = 422
Score = 213 bits (542), Expect = 2e-53, Method: Composition-based stats.
Identities = 141/421 (33%), Positives = 228/421 (54%), Gaps = 6/421 (1%)
Query: 1 MLLKNCKIL--KNGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVH 58
+L+KN +++ K+ + + D+LI +I KI+ I+ + ID V G +D HVH
Sbjct: 2 ILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVH 61
Query: 59 WREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIP 118
+REPG + KE ++T + AAA GG TTV+ M N NPV VETL + L + I
Sbjct: 62 FREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEK-IHIYT 120
Query: 119 YGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCED 177
++T+ G++++D + + + +F+DDG ++S+ V+ EA + + I H ED
Sbjct: 121 NASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEED 180
Query: 178 NSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAV 237
L +EG G + E + IARD+++A H H+ H+S ESV+ V
Sbjct: 181 PQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVV 240
Query: 238 REGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDII 297
++ +VT EV+P H + ++ + KMNPPLR + DR A+I G+ G I +I
Sbjct: 241 AFAQQLGAKVTAEVSPQHFSTTEDLLLIAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVI 300
Query: 298 ATDHAPHTMEEK-IRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
ATDHAPH +EK + + K+ G+ G ET+ + T V+ +L L++ M+ N A +
Sbjct: 301 ATDHAPHHKDEKTVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALL 360
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIA 416
+ G L EN AD+V+ ++E I E F SK N+P+ K+ G+ TI++G++
Sbjct: 361 YGFDAGYLAENGPADLVIFADKQERLIT-ENFASKASNSPFIGNKLKGVVKYTIADGEVV 419
Query: 417 Y 417
Y
Sbjct: 420 Y 420
>gi|27380211|ref|NP_771740.1| dihydroorotase [Bradyrhizobium japonicum USDA 110]
gi|27353365|dbj|BAC50365.1| blr5100 [Bradyrhizobium japonicum USDA 110]
Length = 436
Score = 213 bits (541), Expect = 3e-53, Method: Composition-based stats.
Identities = 128/405 (31%), Positives = 205/405 (50%), Gaps = 6/405 (1%)
Query: 18 DILIKDDKIEKISENIDVTD----ENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTA 73
D+LI D I + I + ++ + V G ID EPGFS +ET +A
Sbjct: 30 DVLIADGIIRETRRGIGAAGVPEGTDVVNCAGKIVAPGLIDMKAFVGEPGFSHRETFASA 89
Query: 74 SRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSD 133
S+AAA GG TT++ P+ PV D+ T++ + ++ +++ P A+TK G E+++
Sbjct: 90 SQAAATGGITTIICQPDTEPVIDNSATVDFVMRRARDTAIVNIQPMAALTKGMRGEEMTE 149
Query: 134 MEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRS 192
+ A AF+D R V +A VM A+ + IV H ED L+ G M+EG+ +
Sbjct: 150 FGLLKAAGAIAFSDGDRSVTNAQVMRRALTYARDFDALIVHHTEDPDLVGEGVMNEGEFA 209
Query: 193 AELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVT 252
+ LG+ GIP+ E+ + RD+ L YH +S +S+ ++ + + V+ V+
Sbjct: 210 SRLGLMGIPNAAEAVMLERDMRLVALTGGRYHAASLSCIDSLDILKRARDAGLAVSASVS 269
Query: 253 PHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRG 312
+HL + DI K++PPLR +DR AL+A V G ID+I +DH P +E K
Sbjct: 270 INHLALNENDIGPYRSFLKLSPPLRTEDDRRALVAAVASGLIDVIMSDHNPQDVEVKRLP 329
Query: 313 IEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADI 372
+++ G VG ET + + L+ L++ MS A+I LP G L S AD+
Sbjct: 330 FAEAAPGAVGLETMLPA-GLRLMHNGELDLKTLIQAMSTRPAEILGLPGGTLRAGSPADV 388
Query: 373 VVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
+VID + ++P E S +NTP+ + G V TI G+ +
Sbjct: 389 IVIDPDVPWVVDPAELKSPCKNTPFDEARFTGRVVRTIVGGRTVF 433
>gi|110638193|ref|YP_678402.1| dihydroorotase [Cytophaga hutchinsonii ATCC 33406]
gi|110280874|gb|ABG59060.1| dihydroorotase [Cytophaga hutchinsonii ATCC 33406]
Length = 421
Score = 211 bits (536), Expect = 9e-53, Method: Composition-based stats.
Identities = 128/412 (31%), Positives = 223/412 (54%), Gaps = 14/412 (3%)
Query: 11 NGKFKKVDILIKDDKIEKISENIDVTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETV 70
NGK + ILI++ I+KIS+ +++ + I+ K V+ G++D V +PG KE +
Sbjct: 19 NGKIRS--ILIENGIIKKISDK-ELSADTVIEAKGMKVSLGWMDMRVTTGDPGHEYKEDL 75
Query: 71 YTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKN---DSVIRAIPYGAITKEEY 127
+A AA +GGFT + +PN P S E++ E +K + ++ P A+T
Sbjct: 76 NSACNAAMQGGFTAIAVLPNTTPPMQSKESV----EYVKGKTREKLVDVYPIAALTLNNK 131
Query: 128 GRELSDMEDI-ADKVFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAM 186
G EL+++ D+ A AF+D + + ++++ A+L +N ++ H ED L GG M
Sbjct: 132 GEELTEILDMNASGAIAFSDGVKPIWHSDLLLRALLYMQPINAQLIVHAEDKYLSHGGQM 191
Query: 187 HEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIR 246
+EGK S LG+KGIP + E + RD+ + E H HIS+ +S+ ++E KK +
Sbjct: 192 NEGKTSTMLGLKGIPKLSEQIMVDRDLSILEYTGGKIHFAHISSPKSLELIKEAKKKGLN 251
Query: 247 VTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTM 306
VTC++ + L D + + K+NPPLR + D + + DGT+D+I +DH P
Sbjct: 252 VTCDIASYQLALDDTMLSSFDSNLKVNPPLRSKRDIDVFWKYINDGTVDVIVSDHIPQDT 311
Query: 307 EEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEE 366
E K +++ FG++G ET F+ + T K + L +++ ++ + N+ +L+E
Sbjct: 312 ECKQLEFDQADFGMIGLETMFSVVNTYNTKIE---LAKIIEKITVAPRAVLNINVPQLKE 368
Query: 367 NSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAYI 418
+ A++ V D EKE ++ + SK NTP+ +K+ G V I+N ++ Y+
Sbjct: 369 GAKANLTVFDTEKEWILSAADLRSKSVNTPFIGKKMKGRAVAVINNNQLTYV 420
>gi|86133737|ref|ZP_01052319.1| dihydroorotase, multifunctional complex type [Tenacibaculum sp.
MED152]
gi|85820600|gb|EAQ41747.1| dihydroorotase, multifunctional complex type [Polaribacter
dokdonensis MED152]
Length = 418
Score = 210 bits (535), Expect = 1e-52, Method: Composition-based stats.
Identities = 129/408 (31%), Positives = 215/408 (52%), Gaps = 12/408 (2%)
Query: 2 LLKNCKILKNGK---FKKVDILIKDDKIEKISENIDVTDE-NTIDVKDRFVTAGFIDAHV 57
LLKN I+ ++ DILI + IEKIS++I D N I++++ ++ G+ D V
Sbjct: 4 LLKNATIVDASSPYHHQQKDILINNGIIEKISDSISADDTTNIIELENLHISCGWFDTSV 63
Query: 58 HWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAI 117
EPGF ++ET+ + AA GFT + N NPV DS + + +N V
Sbjct: 64 SLGEPGFEERETIANGLKVAAESGFTAIAVNSNTNPVIDSKSDVEYLINKARNSGVT-LY 122
Query: 118 PYGAITKEEYGRELSDMEDIADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCE 176
P A+T++ G+EL+++ D+ AF+D + V+S N+M A+L + +++ +
Sbjct: 123 PIAALTQKSEGKELAELYDMQQSGAIAFSDYNKPVESDNLMKVALLYAQNFDGLVLSFPK 182
Query: 177 DNSLIRGGAMHEGKRSAELGIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRA 236
+NS+ G ++EG S +LG+KG P++ E QI RD+ L E H+ IS +SV
Sbjct: 183 NNSISGEGIVNEGINSTKLGLKGTPTLAEHIQIDRDLFLLEYTGGKLHIPTISTAKSVDL 242
Query: 237 VREGKKNNIRVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDI 296
++E K ++VTC V+ HHL D ++ + +K NPPLR +DR AL+ G+ G IDI
Sbjct: 243 IKEAKMKGLQVTCSVSAHHLTLTDNELHGFDSRFKTNPPLRTDKDRKALVKGIKSGVIDI 302
Query: 297 IATDHAPHTMEEKIRGIEKSSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKI 356
I +DH P +E K ++ G++G ET F T + L+ L+ ++ I
Sbjct: 303 ITSDHNPIDIEHKKVEFSEAKDGVIGLETLFPATNT------VLDLDDLINALTTKPRAI 356
Query: 357 FNLPYGKLEENSFADIVVIDLEKEITINPEEFLSKGRNTPYANEKVNG 404
F L ++E++ DI + + + + S +N+P+ +K+ G
Sbjct: 357 FGLESTSIKEDNKVDITLFNPDNNFIFTDKHIASTSKNSPFVGKKLKG 404
>gi|89091929|ref|ZP_01164884.1| dihydroorotase, multifunctional complex type [Oceanospirillum sp.
MED92]
gi|89083664|gb|EAR62881.1| dihydroorotase, multifunctional complex type [Oceanospirillum sp.
MED92]
Length = 426
Score = 209 bits (533), Expect = 2e-52, Method: Composition-based stats.
Identities = 127/402 (31%), Positives = 208/402 (51%), Gaps = 3/402 (0%)
Query: 18 DILIKDDKIEKISENID-VTDENTIDVKDRFVTAGFIDAHVHWREPGFSKKETVYTASRA 76
++ I D KI + E D + + ID ++ V GFID H EPG S+K ++ T S A
Sbjct: 22 NLYISDGKILAVGEAPDNFSADQIIDASNKVVCPGFIDLSAHTCEPGPSQKGSIKTESDA 81
Query: 77 AARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKNDSVIRAIPYGAITKEEYGRELSDMED 136
A GG TT+MT P PV D+ + + ++ +P GA+TK G +L+ M
Sbjct: 82 AVAGGVTTLMTPPTTAPVIDTSAVAELIKDRCEEAGKMQILPMGALTKGLDGEQLAPMAA 141
Query: 137 IADK-VFAFTDDGRGVQSANVMYEAMLMGSKLNKAIVAHCEDNSLIRGGAMHEGKRSAEL 195
+A AF++ + V ++ ++ + + + +V +D +L +GG+MH+G L
Sbjct: 142 LASSGCVAFSNCRKPVANSLILMRCLEYAATHDLLVVFQAQDEALAKGGSMHDGSTCTRL 201
Query: 196 GIKGIPSICESTQIARDILLAEAANCHYHVCHISAKESVRAVREGKKNNIRVTCEVTPHH 255
G+ GIP E+ ++AR +L+AE H +S + SVR + E ++ + VT +V+ +
Sbjct: 202 GLNGIPESAETIEVARCLLMAEQTGVRAHFGQLSCERSVRMISEARERGLPVTADVSIQN 261
Query: 256 LLSCDEDIKEDNGMWKMNPPLRGREDRNALIAGVLDGTIDIIATDHAPHTMEEKIRGIEK 315
LL DE++ N + + PPLR + DR LI G+L GTI I +DH PH K
Sbjct: 262 LLLTDENVNGFNNDFHLIPPLRSQLDRAGLIQGLLSGTIQAICSDHQPHERAAKEAPFAD 321
Query: 316 SSFGIVGSETAFTQLYTKFVKTDIFSLEMLVKLMSENVAKIFNLPYGKLEENSFADIVVI 375
+ G++G ET + L V+ ++ L L++ ++ A+I L G L A+I +
Sbjct: 322 TESGMIGLETLLS-LTLILVEQNMLELPQLIEKLTSAPAEILGLETGTLTVGKPANIAIF 380
Query: 376 DLEKEITINPEEFLSKGRNTPYANEKVNGIPVLTISNGKIAY 417
D E E +N E S+G+NTP+ + + G T+ GK+ Y
Sbjct: 381 DQEMEWALNAETCHSRGKNTPFMDYPLKGRVCTTLFKGKVVY 422
Database: nr
Posted date: Sep 17, 2007 11:41 AM
Number of letters in database: 999,999,834
Number of sequences in database: 2,976,859
Database: /nucleus1/users/jsaw/ncbi/db/nr.01
Posted date: Sep 17, 2007 11:48 AM
Number of letters in database: 894,087,890
Number of sequences in database: 2,493,262
Lambda K H
0.316 0.134 0.382
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,512,455,893
Number of Sequences: 5470121
Number of extensions: 63637223
Number of successful extensions: 189951
Number of sequences better than 1.0e-05: 500
Number of HSP's better than 0.0 without gapping: 754
Number of HSP's successfully gapped in prelim test: 551
Number of HSP's that attempted gapping in prelim test: 186037
Number of HSP's gapped (non-prelim): 1588
length of query: 425
length of database: 1,894,087,724
effective HSP length: 136
effective length of query: 289
effective length of database: 1,150,151,268
effective search space: 332393716452
effective search space used: 332393716452
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 131 (55.1 bits)