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TABLE OF CONTENTS
INTRODUCTION
DISEASES CATEGORIZED BY SITE, PATTERN, AND CYTOLOGY
I. DISORDERS MOSTLY LIMITED TO THE EPIDERMIS & STRATUM CORNEUM
A. Hyperkeratosis With Hypogranulosis
1. No inflammation
Ichthyosis vulgaris
B. Hyperkeratosis With Normal or Hypergranulosis
1. No Inflammation
X-linked ichthyosis
Epidermolytic hyperkeratosis
Epidermodysplasia verruciformis
2. Scant Inflammation
Lichen amyloidosis and Macular amyloidosis.
C. Hyperkeratosis With Parakeratosis
1. Scant or No Inflammation
Dermatophytosis
Granular Parakeratosis
D. Localized or Diffuse Hyperpigmentations
1. No Inflammation
Mucosal melanotic macules
Ephelids (Freckles)
2. Scant Inflammation
Pityriasis (tinea) versicolor
E. Localized or Diffuse Hypopigmentations
1. With or Without Slight Inflammation
Vitiligo
References for Section I
II. LOCALIZED SUPERFICIAL EPIDERMAL OR MELANOCYTIC PROLIFERATIONS
A. Localized Irregular Thickening Of The Epidermis
1. Localized Epidermal Proliferations
Actinic keratosis
Eccrine Poroma
Squamous Cell Carcinoma in Situ & Bowen's Disease
Bowenoid papulosis
Clear cell squamous cell carcinoma in situ
Clear cell acanthoma
2. Superficial Melanocytic Proliferations
Superficial melanocytic nevi and melanomas
Pigmented Spindle Cell Nevus
Acral Lentiginous Melanoma
B. Localized Lesions with Thinning of the Epidermis
1. With Melanocytic Proliferation
Lentigo maligna melanoma, in situ or microinvasive
Recurrent ("persistent") nevus, lentiginous patterns.
Superficial atypical melanocytic proliferations of uncertain significance (SAMPUS), lentiginous patterns
2. Without Melanocytic Proliferation
Atrophic actinic keratosis
Porokeratosis
C. Localized Lesions with Elongated Rete Ridges
1. With Melanocytic Proliferation
Actinic lentigo
Lentigo Simplex
Lentiginous junctional nevus
Nevus spilus
Junctional or superficial compound dysplastic nevi
2. Without Melanocytic Proliferation
Epidermal nevus
Seborrheic keratosis
Acanthosis nigricans
D. Localized Lesions with Pagetoid Epithelial Proliferation
1. Keratinocytic Proliferations
Pagetoid squamous cell carcinoma in situ
Clonal seborrheic keratosis
2. Melanocytic Proliferation
Melanoma in situ or microinvasive, superficial spreading type
Recurrent Nevus (Pseudomelanoma), pagetoid patterns
Junctional Spitz tumor (nevus) with pagetoid proliferation.
Superficial/Intraepidermal atypical melanocytic proliferations of uncertain significance (SAMPUS/IAMPUS), pagetoid patterns
3. Glandular Epithelial Proliferations
Paget's Disease
4. Lymphoid Proliferations
E. Localized Papillomatous Epithelial Lesions
1. With Viral Cytopathic Effects
Verruca Vulgaris
Verruca Plana
Deep Palmoplantar Warts (Myrmecia)
Condyloma Acuminatum
Molluscum contagiosum
Parapox virus infections (milkers' nodules, orf)
2. No Viral Cytopathic Effect
Seborrheic Keratosis
Confluent and Reticulated Papillomatosis (Gougerot-Carteaud)
F. Irregular Proliferations Extending into the Superficial Dermis
1. Squamous Differentiation
Inverted follicular keratosis
2. Basaloid Differentiation
Basal cell carcinoma
G. Superficial Polypoid Lesions
1. Melanocytic Lesions
Polypoid dermal and compound nevi
2. Spindle Cell and Stromal Lesions
Neurofibroma
Fibroepithelial polyp
References for Section II
III. DISORDERS OF THE SUPERFICIAL CUTANEOUS REACTIVE UNIT
A. Superficial Perivascular Dermatitis
1. Superficial Perivascular Dermatitis, Mostly Lymphocytes
Viral exanthem
Tinea versicolor
Lupus erythematosus, acute
Guttate parapsoriasis
1a. Superficial Perivascular Dermatitis with Eosinophils
Morbilliform drug eruption
Allergic urticarial reaction (morbilliform drug eruption)
Urticaria
Urticarial bullous pemphigoid.
1b. Superficial Perivascular Dermatitis with Neutrophils
Erysipelas
Erysipelas/Cellulitis
1c. Superficial Perivascular Dermatitis with Plasma Cells
Secondary syphilis
Kaposi's sarcoma, patch stage
1d. Superficial Perivascular Dermatitis, with Extravasated Red Cells
Pityriasis rosea
Pityriasis lichenoides
Pigmented Purpuric Dermatosis
1e. Superficial Perivascular Dermatitis, Melanophages Prominent
Post-inflammatory hyperpigmentation
2. Superficial Perivascular Dermatitis, Mast Cells Predominant
Urticaria pigmentosa
B. Superficial Dermatitis with Spongiosis (Spongiotic Dermatitis)
1. Spongiotic Dermatitis, Lymphocytes Predominant
Nummular dermatitis (eczema)
Meyerson's nevus
1a. Spongiotic Dermatitis, with Eosinophils
Allergic contact dermatitis
Allergic contact dermatitis.
1b. Spongiotic Dermatitis, with Plasma Cells
1c. Spongiotic Dermatitis, with Neutrophils
Seborrheic dermatitis
C. Superficial Dermatitis with Epidermal Atrophy (Atrophic Dermatitis)
1. Atrophic Dermatitis, Scant Inflammatory Infiltrates
Aged skin
Radiation dermatitis (see also VF1)
2. Atrophic Dermatitis, Lymphocytes Predominant
Poikiloderma atrophicans vasculare
Dermatomyositis
3. Atrophic Dermatitis with Papillary Dermal Sclerosis
Lichen sclerosus et atrophicus
D. Superficial Dermatitis with Psoriasiform Proliferation (Psoriasiform Dermatitis)
1. Psoriasiform Dermatitis, Mostly Lymphocytes
Pityriasis rubra pilaris
Mycosis Fungoides, Patch-Plaque stage
Parapsoriasis
1a. Psoriasiform Dermatitis, with Plasma Cells
Lichen simplex chronicus (see also IIIE)
1b. Psoriasiform Dermatitis, with Eosinophils
Chronic allergic dermatitis
2. Psoriasiform Dermatitis, Neutrophils Prominent (Neutrophilic/Pustular Psoriasiform Dermatitis)
Psoriasis Vulgaris
3. Psoriasiform Dermatitis, with Epidermal Pallor and Necrosis ("Nutritional Pattern" Dermatoses)
Necrolytic Migratory Erythema (Glucagonoma Syndrome)
Necrolytic Acral Erythema
Pellagra
E. Superficial Dermatitis with Irregular Epidermal Proliferation ("Hypertrophic Dermatitis")
1. Hypertrophic Dermatitis, Lymphocytes Predominant
Prurigo nodularis
1a. Irregular Epidermal Proliferation, Plasma Cells Present
Actinic keratosis (see also IIA1)
2. Irregular Epidermal Proliferation, Neutrophils Prominent
Keratoacanthoma (see also VIB1)
3. Irregular Epidermal Proliferation, Above A Neoplasm
Verrucous melanoma (see also VIB3)
F. Superficial Dermatitis with Lichenoid Infiltrates (Lichenoid Dermatitis)
1. Lichenoid Dermatitis, Lymphocytes Exclusively
Lichen planus
Graft v host disease
Mycosis fungoides, patch/plaque stage
2. Lichenoid Dermatitis, Lymphocytes Predominant
Lichen planus-like keratosis (benign lichenoid keratosis)
2a. Lichenoid Dermatitis, Eosinophils Present
Lichenoid drug eruptions
2b. Lichenoid Dermatitis, Plasma Cells Present
Lichenoid actinic keratosis
Secondary syphilis
2c. Lichenoid Dermatitis, with Melanophages
3. Lichenoid Dermatitis, Histiocytes Predominant
Lichen Nitidus
4. Lichenoid Dermatitis, Mast Cells Predominant
Urticaria pigmentosa, lichenoid examples (see also IIIA.2)
5. Lichenoid Dermatitis with Dermal Fibroplasia
Mycosis fungoides, patch stage
G. Superficial Vasculitis and Vasculopathies
1. Neutrophilic Vasculitis
Cutaneous necrotizing (leukocytoclastic) vasculitis
Gonococcemia
2. Mixed Cell and Granulomatous Vasculitis
Granuloma Faciale
3. Vasculopathies with Lymphocytic Inflammation
Pigmented purpuric dermatoses
4. Vasculopathies with Scant Inflammation
Stasis Dermatitis
Stasis dermatitis
5. Thrombotic, Embolic and Other Microangiopathies
Lupus anticoagulant & antiocardiolipin syndromes
Cryoglobulinemia.
H. Superficial Dermatitis with Interface Vacuoles (Interface Dermatitis)
1. Vacuolar Dermatitis, Apoptotic/Necrotic Cells Prominent
Erythema multiforme
Fixed drug eruption
Graft versus host disease, acute
2. Vacuolar Dermatitis, Apoptotic Cells usually Absent
Dermatomyositis
3. Vacuolar Dermatitis, Variable Apoptosis
Subacute Cutaneous Lupus Erythematosus
4. Vacuolar Dermatitis, Basement Membranes Thickened
Discoid Lupus Erythematosus
References for Section III
IV. ACANTHOLYTIC, VESICULAR AND PUSTULAR DISORDERS
A. Subcorneal or Intracorneal Separation
1. Sub/Intracorneal Separation, Scant Inflammatory Cells
Pemphigus Foliaceus
2. Sub/Intracorneal Separation, Neutrophils Prominent
Impetigo Contagiosa
Folliculitis with subcorneal pustule formation
Acute generalized exanthematous pustulosis (AGEP)
3. Sub/Intracorneal Separation, Eosinophils Predominant
Erythema Toxicum Neonatorum
B. Intraspinous Keratinocyte Separation, Spongiotic
1. Intraspinous Spongiosis, Scant Inflammatory Cells
Friction blister
2. Intraspinous Spongiosis, Lymphocytes Predominant
Dyshidrotic Dermatitis (Eczema)
2a. Intraspinous Spongiosis, Eosinophils Present
Incontinentia pigmenti
3. Intraspinous Spongiosis, Neutrophils Predominant
C. Intraspinous Keratinocyte Separation, Acantholytic
1. Intraspinous Acantholysis, Scant Inflammatory Cells
Familial benign pemphigus (Hailey-Hailey disease)
Transient Acantholytic Dermatosis (Grover's Disease)
2. Intraspinous Acantholysis, Predominant Lymphocytes
Herpes simplex
Varicella-zoster infection
Toxic epidermal necrolysis and erythema multiforme with intraepidermal vesiculation (see also IIIH1)
Paraneoplastic pemphigus (PNP)
2a. Intraspinous Acantholysis, Eosinophils Present
Pemphigus Vegetans
3. Intraspinous Separation, Neutrophils or Mixed Cell types
IgA Pemphigus
D. Suprabasal Keratinocyte Separation
1. Suprabasal Vesicles, Scant Inflammatory Cells
Keratosis follicularis (Darier's disease)
Warty dyskeratoma
2. Suprabasal Separation, Lymphocytes & Plasma Cells
Acantholytic actinic keratosis
3. Suprabasal Vesicles, Lymphocytes & Eosinophils
Pemphigus Vulgaris
E. Subepidermal Vesicular Dermatitis
1. Subepidermal Vesicles, Scant /No Inflammation
Porphyria cutanea tarda and other porphyrias
2. Subepidermal Vesicles, Lymphocytes Predominant
Bullous lichen planus
Polymorphous (polymorphic) light eruption (PMLE)
Bullous dermatophytosis
3. Subepidermal Vesicles, Eosinophils Prominent
Bullous pemphigoid
4. Subepidermal Vesicles, Neutrophils Prominent
Dermatitis herpetiformis
Linear IgA Dermatosis
Bullous lupus erythematosus
5. Subepidermal Vesicles, Mast Cells Prominent
Bullous mastocytosis
References for Section IV
V. PERIVASCULAR, DIFFUSE & GRANULOMATOUS INFILTRATES OF THE RETICULAR DERMIS
A. Superficial and Deep Perivascular Infiltrates without Vasculitis
1. Perivascular Infiltrates, Lymphocytes Predominant
Erythema annulare centrifugum
Erythema chronicum migrans (see also VA5)
Tumid lupus erythematosus
2. Perivascular infiltrates, Neutrophils Predominant
Cellulitis
3. Perivascular Infiltrates, Lymphocytes and Eosinophils
Papular urticaria
Pruritic urticarial papules and plaques of pregnancy
4. Perivascular Infiltrates, with Plasma Cells
Secondary syphilis
Tertiary syphilis
Morphea (see also VF)
5. Perivascular Infiltrates, Mixed Cell Types
Erythema Chronicum Migrans
B. Vasculitis and Vasculopathies
1. Vascular Damage, Scant Inflammatory Cells
Degos' Syndrome
2. Vasculitis, Lymphocytes Predominant
Pernio
Pityriasis lichenoides
Cytomegalovirus infection
Erythema chronicum migrans
3. Vasculitis, Neutrophils Prominent
Polyarteritis Nodosa and Microscopic Polyangiitis
Leukocytoclastic vasculitis
Erythema elevatum diutinum
4. Vasculitis, Mixed Cell Types and/or Granulomas
Churg-Strauss Syndrome (Allergic granulomatosis)
Papulonecrotic tuberculid
5. Thrombotic and Other Microangiopathies
Calciphylaxis
Livedo Reticularis
C. Diffuse Infiltrates of the Reticular Dermis
1. Diffuse Infiltrates, Lymphocytes Predominant
Jessner's Lymphocytic Infiltration of the Skin
Leukemia cutis
2. Diffuse Infiltrates, Neutrophils Predominant
Acute Febrile Neutrophilic Dermatosis (Sweet's Syndrome)
Neutrophilic Dermatosis of the Dorsal Hands
Erysipelas
3. Diffuse Infiltrates, "Histiocytoid" Cells Predominant
Lepromatous (LL) Leprosy
Langerhans cell histiocytosis (Histiocytosis X)
Xanthelasma
4. Diffuse Infiltrates, Plasma Cells Prominent
Secondary syphilis
5. Diffuse Infiltrates, Mast Cells Predominant
6. Diffuse Infiltrates, Eosinophils Predominant
Eosinophilic cellulitis (Wells' syndrome)
Tick bite
7. Diffuse Infiltrates, Mixed Cell Types
Cutaneous Leishmaniasis
8. Diffuse Infiltrates, Pigment Cells
Nevi of Ota and Ito and Dermal Melanocyte Hamartoma
9. Diffuse Infiltrates, Extensive Necrosis
Gangrenous ischemic necrosis
D. Diffuse or Nodular Infiltrates of the Reticular Dermis with Epidermal Proliferation
1. Epidermal Proliferation with Mixed Cellular Infiltrates
North American blastomycosis
Deep fungal infections-general
E. Nodular Inflammatory Infiltrates of the Reticular Dermis - Granulomas, Abscesses & Ulcers
1. Epithelioid Cell Granulomas without Necrosis
Sarcoidosis
Lupus vulgaris
2. Epithelioid Cell Granulomas with Necrosis
Tuberculosis
Tuberculoid leprosy
Lupus miliaris disseminatus facei (granulomatous rosacea)
3. Palisading Granulomas
Granuloma annulare
Necrobiosis lipoidica diabeticorum (NLD)
Necrobiotic xanthogranuloma with paraproteinemia
Rheumatoid nodules
Palisaded Neutrophilic and Granulomatous Dermatitis
4. Mixed Cell Granulomas
Foreign-body reactions
5. Inflammatory Nodules with Prominent Eosinophils
Angiolymphoid Hyperplasia with Eosinophilia, and Kimura's Disease
Scabetic nodule
6. Inflammatory Nodules with Mixed Cell Types
Sporotrichosis
Atypical mycobacteria
7. Inflammatory Nodules with Necrosis and Neutrophils (Abscesses)
Botryomycosis
Chromoblastomycosis
8. Inflammatory Nodules with Prominent Necrosis
Aspergillosis
9. Chronic Ulcers & Sinuses Involving the Reticular Dermis
Chancroid
Pyoderma Gangrenosum
Chondrodermatitis nodularis helicis
F. Dermal Matrix Fiber Disorders
1. Fiber Disorders, Collagen Increased
Scleroderma
Radiation dermatitis
Nephrogenic Fibrosing Dermopathy
Regressing melanoma
Superficial scar (e.g. biopsy site reaction)
2. Fiber Disorders, Collagen Reduced
Focal dermal hypoplasia syndrome (Goltz)
3. Fiber Disorders, Elastin Increased or Prominent
Pseudoxanthoma elasticum
4. Fiber Disorders, Elastin Reduced
Macular atrophy (anetoderma)
5. Fiber Disorders, Perforating
Elastosis Perforans Serpiginosum
Reactive perforating collagenosis
Perforating folliculitis
G. Deposition of Material in the Dermis
1. Increased Normal Nonfibrous Matrix Constituents
Digital mucous cysts and focal mucinosis
Mucinosis in lupus erythematosus
Myxedema
Scleredema
Scleromyxedema
2. Increased Material Not Normally Present in the Dermis
Gout
Oxalosis
Colloid milium
Idiopathic Calcinosis Cutis
Cryoglobulinemia
Keratin granuloma
Suture granuloma
Minocycline Pigmentation
3. Parasitic Infestations of the Dermis &/or Subcutis
Larva migrans eruption
References for Section V
VI. TUMORS AND CYSTS OF THE DERMIS & SUBCUTIS
A. Small Cell Tumors
1. Tumors of Lymphocytes or Hemopoietic Cells
Cutaneous B Cell Lymphoma
Cutaneous diffuse B cell lymphoma
Cutaneous T cell lymphoma, tumor stage
2. Tumors of Lymphocytes and Mixed Cell Types
B-Cell Cutaneous Lymphoid Hyperplasia (B-CLH, Pseudolymphoma, Lymphocytoma Cutis)
3. Tumors of Plasma Cells
Cutaneous Plasmacytoma and Multiple Myeloma (MM)
4. Small Round Cell Tumors
Cutaneous Small Cell Undifferentiated Carcinoma (Merkel Cell Tumor)
Metastatic small cell carcinoma
B. Large Polygonal & Round Cell Tumors
1. Squamous Cell Tumors
Squamous cell carcinoma, deep
Keratoacanthoma
Inverted follicular keratosis
Pseudoepitheliomatous hyperplasia (PEH)
Proliferating Trichilemmal Cyst (Pilar Tumor)
Prurigo nodularis
2. Adenocarcinomas
Metastatic adenocarcinoma
Metastatic pulmonary adenocarcinoma
Metastatic mammary carcinoma
3. Melanocytic Tumors
3a. Melanocytic Lesions with Little or No Cytologic Atypia.
Melanocytic Nevi, Acquired And Congenital Types
Acquired nevi
Congenital nevus
Acral nevus
Balloon cell nevus
Halo Nevus
Blue nevus
Cellular Blue Nevus
3b. Melanocytic Lesions with Cytologic Atypia
Deep penetrating nevus
Spitz Tumor/Nevus
Nodular Melanoma
Nevoid melanoma
Metastatic Malignant Melanoma
Metastatic malignant melanoma, satellite lesion
Epidermotropic metastatic melanoma
Pigmented Epithelioid Melanocytoma (PEM)/Epithelioid blue nevus
Melanocytic Tumor of Uncertain Malignant Potential
4. Eccrine Tumors
4a. Circumscribed, Symmetrical Eccrine Tumors
Eccrine Spiradenoma
Cylindroma
Poroma
Syringoma
Nodular Hidradenoma
Clear cell syringoma
Chondroid syringoma
4b. Infiltrative, Asymmetrical Eccrine Tumors
Microcystic Adnexal Carcinoma
Mucinous eccrine carcinoma
Digital Papillary Adenocarcinoma
5. Apocrine Tumors
Tubular Apocrine Adenoma
Syringocystadenoma papilliferum
6. Pilar Tumors
Trichoepithelioma
Desmoplastic trichoepithelioma
Dilated pore of Winer
Pilar sheath acanthoma
Trichilemmoma
Trichofolliculoma
Fibrofolliculoma
Trichoadenoma
Pilomatricoma
Trichoblastoma
7. Sebaceous Tumors
Sebaceous Adenoma and Sebaceous Epithelioma (Sebaceoma)
Sebaceous hyperplasia
Nevus sebaceus of Jadassohn
Sebaceous epithelioma
Sebaceous Carcinoma
8. "Histiocytoid" Tumors
Xanthomas and Xanthelasma
Xanthelasma
Eruptive xanthoma
Verruciform xanthoma
Juvenile xanthogranuloma (JXG)
Reticulohistiocytosis
Metastatic renal cell carcinoma
9. Tumors of Large Lymphoid Cells
Cutaneous CD30+ (Ki-1+) Anaplastic Large-Cell Lymphoma (ALCL)
Lymphomatoid Papulosis
Leukemia Cutis
10. Mast Cell Tumors
Urticaria pigmentosa, nodular lesions (see also IIIA.2).
11. Tumors with Prominent Necrosis
Epithelioid sarcoma
12. Miscellaneous & Undifferentiated Epithelial Tumors
Granular cell tumor
Cellular neurothekeoma
Metastatic malignant melanoma
C. Spindle Cell, Pleomorphic & Connective Tissue Tumors
1. Fibrohistiocytic Spindle Cell Tumors
1a. Fibrohistiocytic tumors with minimal or no atypia.
Dermatofibroma
Cellular Dermatofibroma
Sclerosing/angiomatoid Spitz nevus (desmoplastic Spitz nevus)
Dermatofibrosarcoma protuberans
Fibrous papule (angiofibroma),
Recurrent infantile digital fibromatosis
Keloid
Acquired digital fibrokeratoma
Giant cell tumor of tendon sheath
Nodular fasciitis
1b. Fibrohistiocytic tumors with high grade atypia.
Atypical fibroxanthoma
Malignant fibrous histiocytoma
1c. Lesions with myxoid changes.
Mucocele
Digital mucous cyst
Cutaneous myxoma
2. Schwannian/Neural Spindle Cell Tumors
Neurofibromas
Neurofibromatosis
Schwannoma (neurilemmoma)
Palisaded encapsulated neuroma
Accessory digit
3. Spindle Cell Tumors Of Muscle
Leiomyomas
Angioleiomyoma
Smooth muscle hamartoma
Leiomyosarcoma
4. Melanocytic Spindle Cell Tumors
Desmoplastic melanoma
5. Tumors and Proliferations of Angiogenic Cells
Pyogenic Granuloma (Lobular Capillary Hemangioma)
Intravascular Papillary Endothelial Hyperplasia (Masson's Hemangio-Endotheliome Vegetant Intravasculaire)
Stasis Dermatitis with vascular proliferation (acroangiodermatitis, pseudo-Kaposi's sarcoma)
Kaposi's Sarcoma
Diffuse Dermal Angiomatosis
Cutaneous Angiosarcoma
Epithelioid hemangioendothelioma
Targetoid Hemosiderotic Hemangioma (Hobnail Hemangioma)
Angiokeratoma
Arteriovenous hemangioma
Cavernous hemangioma
Cherry hemangioma
Microvenular hemangioma
Cutaneous lymphangioma
Venous lake
Glomangioma
Subungual glomus tumor
6. Tumors of Adipose Tissue
Nevus lipomatosus superficialis
Lipoma
Angiolipomas
Spindle cell lipoma
Pleomorphic lipoma
Liposarcoma
7. Tumors of Cartilaginous Tissue
8. Tumors of Osseous Tissue
Albright's hereditary osteodystrophy & Osteoma cutis
D. Cysts of the Dermis and Subcutis
1. Pilar Differentiation
Epidermal or infundibular cyst
Trichilemmal (pilar) cyst
Steatocystoma
Vellus hair cyst
2. Eccrine and Similar Differentiation
Eccrine Hidrocystoma
Median raphe cyst
Bronchogenic cyst
Cutaneous endometriosis
3. Apocrine Differentiation
Apocrine Hidrocystoma
Hidradenoma Papilliferum
References for Section VI
VII. INFLAMMATORY & OTHER BENIGN DISORDERS OF SKIN APPENDAGES
A. Pathology Involving Hair Follicles
1. Scant Inflammation
Androgenetic alopecia
Trichotillomania
Telogen effluvium
Keratosis pilaris
Scurvy
2. Lymphocytes Predominant
Alopecia areata
Lichen planopilaris
Central Centrifugal Cicatricial Alopecia
Discoid lupus erythematosus of the scalp
Alopecia mucinosa
Rosacea
3. with Prominent Eosinophils
Eosinophilic pustular folliculitis
4. Neutrophils Prominent
Acute deep folliculitis (furuncle)
Tinea capitis
Majocchi's granuloma
Herpes simplex viral folliculitis
4. Plasma Cells Prominent
Folliculitis (acne) keloidalis nuchae
Tinea capitis
5. Fibrosing and Suppurative Follicular Disorders
Follicular occlusion triad (hidradenitis suppurativa, acne conglobata, and perifolliculitis capitis abscedens et suffodiens)
Hidradenitis suppurativa
Dissecting cellulitis of the scalp
Folliculitis decalvans
B. Pathology Involving Sweat Glands
1. Scant inflammation
Eccrine nevus
2. Lymphocytes Predominant
Lichen striatus
2a. with Plasma Cells
Lupus erythematosus
2b. with Eosinophils
Arthropod bite
3. Neutrophils Predominant
Neutrophilic eccrine hidradenitis
Idiopathic Recurrent Palmoplantar Hidradenitis
C. Pathology Involving Nerves
1. Lymphocytic Infiltrates
2. Mixed Inflammatory Infiltrates
Nerve involvement in leprosy
Erythema chronica migrans with nerve involvement
Arthropod bite reaction with nerve involvement
3. Neoplastic Infiltrates
Neurotropic melanoma
D. Pathology of the Nails
1. Lymphocytic Infiltrates
Acral lentiginous melanoma
2. Lymphocytes with Neutrophils
Onychomycosis
3. Vesiculobullous Diseases
Darier's disease
4. Parasitic Infestations
Scabies
References for Section VII
VIII. DISORDERS OF THE SUBCUTIS
A. Subcutaneous Vasculitis & Vasculopathy (Septal or Lobular)
1. Neutrophilic Vasculitis
Subcutaneous polyarteritis nodosa (see also VB3)
2. Lymphocytic "Vasculitis"
3. Granulomatous Vasculitis
Erythema induratum (nodular vasculitis)
B. Septal Panniculitis without Vasculitis
1. Septal Panniculitis, Lymphocytes & Mixed Infiltrates
Erythema nodosum
2. Septal Panniculitis, Granulomatous
Subcutaneous granuloma annulare
3. Septal Panniculitis, Sclerotic
Scleroderma and morphea
C. Lobular Panniculitis without Vasculitis
1. Lobular Panniculitis, Lymphocytes Predominant
Lupus erythematosus panniculitis
2. Lobular Panniculitis, Lymphocytes and Plasma Cells
3. Lobular Panniculitis, Neutrophilic
4. Lobular Panniculitis, Eosinophils Prominent
5. Lobular Panniculitis, Histiocytes Prominent
Histiocytic cytophagic panniculitis (subcutaneous T-cell lymphoma with hemophagocytic syndrome)
6. Lobular Panniculitis, Mixed with Foam Cells
Relapsing febrile nodular nonsuppurative panniculitis (Weber-Christian disease)
7. Lobular Panniculitis, Granulomatous
Subcutaneous sarcoidosis
8. Lobular Panniculitis, Crystal Deposits, Calcifications
Subcutaneous fat necrosis of the newborn
Calcifying panniculitis (calciphylaxis)
9. Lobular Panniculitis, Necrosis Prominent
Subcutaneous nodular fat necrosis in pancreatic disease
10. Lobular Panniculitis, Embryonic Fat Pattern
Localized lipoatrophy and lipodystrophy
11. Lobular Panniculitis, Lipomembranous
Lipomembranous change or lipomembranous panniculitis
D. Mixed Lobular & Septal Panniculitis
1. With Hemorrhage or Sclerosis
Panniculitis due to physical or chemical agents
2. With Many Neutrophils
Necrotizing fasciitis
3. With Many Eosinophils
Eosinophilic fasciitis (Shulman's syndrome)
4. With Many Lymphocytes
Subcutaneous panniculitic or lipotropic T-cell lymphoma
5. With Cytophagic Histiocytes
Sinus histiocytosis with massive lymphadenopathy (SHML, Rosai-Dorfman)
6. With Granulomas
Mycobacterial panniculitis
Erythema nodosum leprosum (Type 2 leprosy reaction)
E. Subcutanous Abscesses
1. With Neutrophils
Phaeohyphomycotic Cyst
References for Section VIII
Library of Congress Subject Headings for this publication:
Skin -- Histopathology.
Skin -- Histopathology -- Atlases.
Skin -- pathology -- Atlases.
Skin Diseases -- pathology -- Atlases.