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| Reference: |
Schuerman GS, Van Meervelt L, Loakes D, Brown DM, Kong Thoo Li, Moore MH, Salisbury SAA thymine-like base analogue forms wobble pairs with adenine in a Z-DNA duplexJ. Mol. Biol. v282, p.1005-1011The DNA hexamer d(CACGPG), in which dP is the ambivalent pyrimidine nucleoside analogue 2"-deoxy-beta-d-ribofuranosyl-(6H,8H-3, 4-dihydropyrimido[4,5-c][1,2]oxazin-7-one), crystallises as a left-handed Z-DNA duplex. X-ray analysis at 1.5 A shows that both P. A base-pairs are of the wobble type. This result appears inconsistent with other evidence from hybridisation and NMR studies of P-containing oligonucleotides, which suggests that, while P can form stable base-pairs with either A or G, thymine-like properties are more pronounced....
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| Description: |
A Thymine-Like Base Analogue Forms Wobble Pairs With Adenine. |
| Deposition: |
1998/7/15   |
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| Author: |
N, Lin PKT, Schuerman MHMooreGS, Van Meervelt L, Loakes D, Brown DM, Lin PKT, Moore MH |
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| Taxonomy: |
synthetic construct |
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Molecular components in the MMDB structure are listed below and may include macromolecular chains, 3D domains, protein classifications (domain families), and ligands, as available. Mouse over each icon for more information on the component. 
Citing MMDB:
Wang Y, Addess KJ, Chen J, Geer LY, He J, He S, Lu S, Madej T, Marchler-Bauer A, Thiessen PA, Zhang N, Bryant SH.
"MMDB: annotating protein sequences with Entrez's 3D-structure database.",
Nucleic Acids Res. 2007 Jan; 35(Database issue): D298-300.
Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH.
"MMDB: Entrez's 3D-structure database", Nucleic Acids Res. 2003 Jan; 31(1): 474-7.
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