National Toxicology Program

Selected toxicity information from HSDB, one of the National Library of Medicine's databases. ¹

Names (NTP)

• Lauryl glycidyl ether
• OXIRANE, ((DODECYLOXY)METHYL)- (9CI)

Human Toxicity Excerpts

• GLYCIDYL ETHERS...CHARACTERISTICALLY...ARE VERY IRRITATING TO THE EYES, SKIN AND RESPIRATORY TRACT. /GLYCIDYL ETHERS/ [Grant, W. M. Toxicology of the Eye. 2nd ed. Springfield, Illinois: Charles C. Thomas, 1974., p. 529]**PEER REVIEWED**
  
• EXAMINATION BY UNSCHEDULED DNA SYNTHESIS USING WI38 CELLS SHOWED THAT ALKYL GLYCIDYL ETHERS C-8 OR HIGHER SHOWED VERY WEAK OR NO MUTAGENIC RESPONSES. DODECYL GLYCIDYL ETHER WAS INCLUDED IN THE ASSAY. [THOMPSON ED ET AL; MUTAGENICITY OF ALKYL GLYCIDYL ETHERS IN THREE SHORT-TERM ASSAYS; MUTAT RES 90(3) 213 (1981)]**PEER REVIEWED**
  

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Non-Human Toxicity Excerpts

• WHEN EXAMINED IN THE SALMONELLA/MAMMALIAN MICROSOME ASSAY & THE L5178Y MOUSE LYMPHOMA ASSAY, ALKYL GLYCIDYL ETHERS C-8 OR HIGHER SHOWED VERY WEAK OR NO MUTAGENIC RESPONSES. DODECYL GLYCIDYL ETHER WAS INCLUDED IN THE ASSAY. [THOMPSON ED ET AL; MUTAGENICITY OF ALKYL GLYCIDYL ETHERS IN THREE SHORT-TERM ASSAYS; MUTAT RES 90(3) 213 (1981)]**PEER REVIEWED**
  

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Human Toxicity Values

• None found

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Non-Human Toxicity Values

• None found

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Absorption, Distribution and Excretion

• None found

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Metabolism/Metabolites

• None found

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TSCA Test Submissions

• None found

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Footnotes

¹ Source: the National Library of Medicine's Hazardous Substance Database, 10/28/2007.