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Analysis of presenting symptom complex & clinical features of HIV-positive subjects in Gujarat - India.

Patel AK; International Conference on AIDS.

Int Conf AIDS. 1996 Jul 7-12; 11: 113 (abstract no. Mo.B.1334).

Municipal Medical College, Ahmedabad, Gujarat, India.

Objective: To determine clinical presentation of HIV disease in Gujarat state-India. Method: 88 patients are selected from first 160 patients(pts.) referred to my clinic during last 18 months. Apart from routine hematological, biochemical & radiological investigations, specific test for suspected opportunistic infection are carried out. Result:Total 88 pts., 59-male, 29-female, M:F=1:0.5. Mode of transmission-sexual-42, blood transfusion-40,vertical transmission-1, unknown-5 pts.81.8% pts. fall into age group 21-40 yrs.Common clinical presentations are;fever-75%, weight loss-60.2%, cough-45.5%, skin disorders-36.4%, diarrhea-31.8%, neurological-22.7%, odynophagia-6.8%. On examination:oral thrush-76.4%, recurrent oral ulcer-8,generalised lymphadenopathy-25%. oral hairy leucoplakia-5.7%, arthropathy-6.8%. Final diagnosis: tuberculosis is found in 59% of pts.(29.5%each pulmonary & extra pulmonary),recurrent pneumonia 5.7%, pneumocystis carinii pneumonia 3.4%, wasting syndrome 15.9%, progressive multifocal leucoencephalopathy 3.4%, neurotoxoplasmosis 2.3%, cryptococcal meningitis 1%, candida esophagitis 6.8%, ? cryptosporidial diarrhea 1%, granulomatous hepatitis 3.4%, adrenal insufficiency 4.5%. Hematological abnormalitis-leucopenia 17%, coombs positive hemolytic anemia 2.3%, I.T.P.1%. 57 patients are regularly followed up, 14 patients lost follow up, & 17 patients died. Conclusion: India has entered in to second phase of HIV epidemic.Awareness regarding various clinical presentations of HIV disease is important to detect & manage such cases. PUO, unexplained weight loss, prolong diarrhea, dermatitis, skin pigmentation, vasculitis, cutanious herpes etc.are common presenting complaints. On exam: oral thrush, lymphadenopathy& T.B.are common associated condition.

Publication Types:
  • Meeting Abstracts
Keywords:
  • Acquired Immunodeficiency Syndrome
  • Candidiasis
  • Candidiasis, Oral
  • Disease Transmission, Vertical
  • Female
  • HIV Infections
  • HIV Seropositivity
  • Humans
  • India
  • Leukoplakia, Hairy
  • Male
  • Research
  • Tuberculosis
  • psychology
  • transmission
Other ID:
  • 96921398
UI: 102217297

From Meeting Abstracts




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