Volume 7, Number 5     September/October 1999

Advanced Technologies


A Technology-Based New Product and Company

ONE DOCTOR'S DREAM OF A MEDICAL VERSION of the HAL computer from the movie 2001: A Space Odyssey has culminated in a successful commercial product, the MDX© Clinical Decision Support Technology. NASA's need was to have a system to help astronauts diagnose their own illnesses during long space voyages.

In 1987, Ralph Grams, M.D., a medical systems specialist at the University of Florida's College of Medicine, started working with Kennedy Space Center's Biomedical Office to develop a computer-based medical information and diagnostic support system known as the Clinical Practice Library of Medicine (CPLM). Now, 12 years later, Dr. Grams has formed a new company, Martek Research, Inc., of Gainesville, Florida, to market MDX© and Smart Charts©, Martek's two initial and copyrighted products.

Potential market sources range from health maintenance organizations (HMOs) and large clinical groups to the primary care physician in solo practice. "We also see a role for our product with existing electronic medical record (EMR) vendors who want the best decision support system (DSS) and chart creation tools in the industry," Grams said.

The MDX innovation, contained in one PC-based CD–ROM, is described as a computer-based physician decision support tool that provides a comprehensive differential diagnosis based on patient signs, symptoms and findings, using the traditional medical diagnostic strategy of pattern recognition. This is the customary method by which a physician compares the known with the unknown to see the degree of fit and conformation. The CD–ROM contains a database of textbooks and journals containing the industry standard patterns, and this allows the MDX program to quickly search all known clinical factoids for fit and conformation.

The use of intelligent medical records, or Smart Charts, could potentially effect any patient who visits a physician or goes to a hospital for treatment, Grams said. The MDX portion of the project provides diagnostic support for tough clinical problems and would be used in situations in which doubt or clinical questions are encountered in the care plan. Both of these technologies can improve physician productivity, enhance outcomes and reduce costs by providing reliable primary care clinical decision support tools. The economic benefits are evident when a doctor has legible, letter-perfect charts that teach as well as document the patient care process in the exam room.

The competitive advantage of the MDX and Smart Charts innovations rests with the databases, which are totally unique and very difficult to duplicate. The size and scope of these medical files allow Martek Research to provide superior clinical data during the patient care examination and to direct and control the entire process. This is a total change in style from the blank page and brain-dead systems used in the past. The computer now knows more medicine than any human could memorize in one's lifetime. The system has no limits as to the size of this knowledge base and can grow and change with the company's professional medical updates. The system supports the simple, routine cases and is totally capable of handling the most complex problems.

The MDX CD–ROM contains the largest structured medical database in the world, according to Grams, and is capable of constant updates. Reference texts and journals are the foundation for all these databases so that the files are fully supported for any legal challenge. The data do not represent any small groups' personal opinions, but display the consensus finding of large clinical peer review panels that publish their disease profiles in major referenced documents.

Martek has a publishing joint venture partner with Facts & Comparisons, a St. Louis company that is a leading provider of authoritative drug information to professionals and students in the health professions. It is part of the Wolters Kluwer International Publishing Division, which also includes Lippincott Williams and Wilkins of Philadelphia, Adis Press of New Zealand and Ovid Technologies of New York, together forming one of the leading international information providers to health care professionals.

For more information, contact Lewis Parrish at Kennedy Space Center.
Call: 407/867-6373, E-mail: ParriLM@kscgws00.ksc.nasa.gov
Please mention you read about it in Innovation.

WEATHER SATELLITES TRACK,
CONTROL DISEASE

Using weather satellites to spot the early signs of rising sea temperatures in the eastern Pacific Ocean, the phenomenon called El Niño, scientists may be able to help save East Africans and their livestock from Rift Valley Fever. This mosquito-borne disease can cause death in livestock populations and flu-like symptoms that can be fatal to humans.

In the July 16 issue of the journal Science, researchers from NASA's Goddard Space Flight Center, Greenbelt, Maryland, and the Department of Defense's Global Disease Infections System, Walter Reed Army Institute of Research, Washington, D.C., reported studying nearly five decades of satellite data. They determined that rising sea-surface temperatures in the western equatorial Indian Ocean, combined with an El Niño in the Pacific, can lead to abnormally heavy rains in East Africa. This favorable habitat for the mosquitoes carrying the Rift Valley Fever virus can be predicted up to six months in advance so pesticides can stem the mosquito season before it starts.

Researchers found that an El Niño episode alone does not ensure an outbreak. According to the report, the decisive factor is the warming of the Indian Ocean along with the Pacific, which occurred in two of five El Niños over the last 17 years.

Satellites help determine areas receiving the most rain and being greener than normal. Aedes mosquitoes lay their eggs in moist soil when floodwaters recede. The area refloods, and the young insects hatch and feed on local livestock. The Culex, a second mosquito prevalent during excessive rains, contracts the virus from infected livestock and spreads it to humans.

For more information, contact Lynn Chandler at Goddard Space Flight Center.
Call: 301/286-5662.
Please mention you read about it in Innovation.

 


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