Young MA, Pierce P; International Conference on AIDS.
Int Conf AIDS. 1990 Jun 20-23; 6: 186 (abstract no. F.B.432).
Georgetown University Hospital, Washington, D.C., USA
OBJECTIVE: Women comprise 10% of AIDS cases however, few studies are available documenting the natural history of HIV infection in this group. This retrospective review analyzes demographic features and disease progression in an urban cohort of women. METHODS: 56 women HIV positive by ELISA and WB were evaluated at GUH's HIV Clinical Center from 7/87 to 11/89. A retrospective chart review assessed demographic information, absolute T4 cell count, opportunistic infection (OI), other HIV related events and clinical disposition. RESULTS: Of 281 patients evaluated since 7/87, 56 (20%) were women, age range 17-66 yrs. 32/56 were black, 16 caucasian, 3 hispanic, 2 haitian, 3 other. Risk factors were as follows: 25/56 IV drug use (IVDU), 24 heterosexual contact, 4 blood transfusion, 1 artificial insemination, 2 unknown. 39/56 had a total of 66 children. 6/66 children were presumed to be HIV+, one had expired. 22/56 women presented with absolute T4 cell counts less than 200, 20 with T4 200-500, 14 with T4 greater than 500. 18/56 patients had AIDS defining events, all with T4 less than 200. 12/18 (67%) had PCP, 2 (11%) HIV encephalopathy, 1 CMV, 1 candida esophagitis, 1 Toxo, 1 wasting with fever. The mean T4 of those with PCP was 89 (range 13-102). There have been 32 recorded OI's in these 18 patients, 19 PCP, 3 CMV, 2 Candida esophagitis, 4 MAI. No KS or cryptococcal disease was seen. 7 patients have expired (mean T4 44). CONCLUSION: Urban women presenting for + HIV testing were likely to be black (57%), in their twenties (41%), with children (70%), and to have almost equal risk from IVDU (45%) or heterosexual transmission (43%). Women present late in the disease process, 39% with T4 less than 200, 36% T4 200-500. The most common AIDS defining event as in male cohorts is PCP (67%).
Publication Types:
Keywords:
- AIDS Dementia Complex
- Acquired Immunodeficiency Syndrome
- CD4-Positive T-Lymphocytes
- Child
- Disease Progression
- Female
- HIV
- HIV Infections
- HIV Seropositivity
- Haiti
- Humans
- Male
- Natural History
- Risk Factors
- transmission
Other ID:
UI: 102184347
From Meeting Abstracts